Amino acid dipepetide frequency for Elderberry carlavirus B

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.211AlaAla: 3.211 ± 1.079
1.07AlaCys: 1.07 ± 0.517
2.141AlaAsp: 2.141 ± 0.473
3.568AlaGlu: 3.568 ± 0.797
3.211AlaPhe: 3.211 ± 1.195
3.211AlaGly: 3.211 ± 0.896
1.784AlaHis: 1.784 ± 0.543
5.351AlaIle: 5.351 ± 1.902
6.065AlaLys: 6.065 ± 1.215
7.849AlaLeu: 7.849 ± 1.619
1.427AlaMet: 1.427 ± 0.929
2.854AlaAsn: 2.854 ± 1.573
2.497AlaPro: 2.497 ± 0.7
1.427AlaGln: 1.427 ± 0.521
2.854AlaArg: 2.854 ± 1.156
5.351AlaSer: 5.351 ± 1.18
4.638AlaThr: 4.638 ± 1.423
3.211AlaVal: 3.211 ± 1.143
0.714AlaTrp: 0.714 ± 0.374
1.427AlaTyr: 1.427 ± 0.515
0.0AlaXaa: 0.0 ± 0.0
Cys
2.854CysAla: 2.854 ± 0.749
0.357CysCys: 0.357 ± 0.187
1.07CysAsp: 1.07 ± 1.562
1.784CysGlu: 1.784 ± 1.318
2.141CysPhe: 2.141 ± 1.121
3.568CysGly: 3.568 ± 1.317
0.714CysHis: 0.714 ± 0.77
3.568CysIle: 3.568 ± 0.548
1.07CysLys: 1.07 ± 0.487
1.427CysLeu: 1.427 ± 0.81
0.357CysMet: 0.357 ± 0.187
0.714CysAsn: 0.714 ± 0.77
1.427CysPro: 1.427 ± 0.788
0.714CysGln: 0.714 ± 0.9
2.497CysArg: 2.497 ± 0.734
3.924CysSer: 3.924 ± 1.135
2.497CysThr: 2.497 ± 0.932
3.924CysVal: 3.924 ± 0.523
0.0CysTrp: 0.0 ± 0.0
0.714CysTyr: 0.714 ± 0.77
0.0CysXaa: 0.0 ± 0.0
Asp
3.211AspAla: 3.211 ± 0.653
1.07AspCys: 1.07 ± 1.063
3.211AspAsp: 3.211 ± 1.079
3.924AspGlu: 3.924 ± 0.955
4.281AspPhe: 4.281 ± 1.374
3.568AspGly: 3.568 ± 1.317
0.357AspHis: 0.357 ± 0.187
2.854AspIle: 2.854 ± 1.867
2.141AspLys: 2.141 ± 1.172
4.638AspLeu: 4.638 ± 1.031
2.141AspMet: 2.141 ± 1.007
2.141AspAsn: 2.141 ± 0.765
3.568AspPro: 3.568 ± 0.84
0.714AspGln: 0.714 ± 0.374
3.568AspArg: 3.568 ± 2.986
3.568AspSer: 3.568 ± 0.548
2.141AspThr: 2.141 ± 0.871
2.497AspVal: 2.497 ± 0.891
0.357AspTrp: 0.357 ± 0.187
2.854AspTyr: 2.854 ± 0.681
0.0AspXaa: 0.0 ± 0.0
Glu
5.708GluAla: 5.708 ± 1.829
2.141GluCys: 2.141 ± 0.916
3.568GluAsp: 3.568 ± 1.394
4.995GluGlu: 4.995 ± 1.652
3.924GluPhe: 3.924 ± 0.89
4.995GluGly: 4.995 ± 1.981
1.427GluHis: 1.427 ± 0.521
4.281GluIle: 4.281 ± 1.247
4.281GluLys: 4.281 ± 1.158
4.995GluLeu: 4.995 ± 2.111
1.07GluMet: 1.07 ± 0.561
2.141GluAsn: 2.141 ± 0.687
3.568GluPro: 3.568 ± 0.807
2.141GluGln: 2.141 ± 1.176
1.784GluArg: 1.784 ± 0.934
3.211GluSer: 3.211 ± 1.39
2.141GluThr: 2.141 ± 0.742
4.995GluVal: 4.995 ± 1.735
0.714GluTrp: 0.714 ± 0.374
2.141GluTyr: 2.141 ± 1.176
0.0GluXaa: 0.0 ± 0.0
Phe
2.854PheAla: 2.854 ± 0.634
1.427PheCys: 1.427 ± 0.747
3.924PheAsp: 3.924 ± 1.256
4.281PheGlu: 4.281 ± 1.483
2.854PhePhe: 2.854 ± 0.681
4.281PheGly: 4.281 ± 2.854
1.427PheHis: 1.427 ± 1.045
3.568PheIle: 3.568 ± 1.95
2.854PheLys: 2.854 ± 0.979
7.135PheLeu: 7.135 ± 3.029
1.784PheMet: 1.784 ± 0.578
2.854PheAsn: 2.854 ± 0.538
0.714PhePro: 0.714 ± 0.374
1.07PheGln: 1.07 ± 0.487
1.07PheArg: 1.07 ± 0.561
6.065PheSer: 6.065 ± 2.085
3.568PheThr: 3.568 ± 1.178
2.854PheVal: 2.854 ± 0.979
0.357PheTrp: 0.357 ± 1.004
1.784PheTyr: 1.784 ± 0.913
0.0PheXaa: 0.0 ± 0.0
Gly
4.995GlyAla: 4.995 ± 1.129
2.854GlyCys: 2.854 ± 1.003
4.281GlyAsp: 4.281 ± 1.17
3.568GlyGlu: 3.568 ± 1.122
5.351GlyPhe: 5.351 ± 1.126
2.854GlyGly: 2.854 ± 1.106
0.714GlyHis: 0.714 ± 0.9
4.281GlyIle: 4.281 ± 1.031
4.638GlyLys: 4.638 ± 2.268
4.638GlyLeu: 4.638 ± 2.222
0.714GlyMet: 0.714 ± 0.374
2.497GlyAsn: 2.497 ± 0.891
1.427GlyPro: 1.427 ± 0.521
3.211GlyGln: 3.211 ± 0.557
4.638GlyArg: 4.638 ± 0.657
3.211GlySer: 3.211 ± 1.221
3.924GlyThr: 3.924 ± 2.003
3.924GlyVal: 3.924 ± 0.869
0.714GlyTrp: 0.714 ± 0.581
1.07GlyTyr: 1.07 ± 0.561
0.0GlyXaa: 0.0 ± 0.0
His
1.427HisAla: 1.427 ± 0.515
1.427HisCys: 1.427 ± 1.049
0.357HisAsp: 0.357 ± 0.187
1.427HisGlu: 1.427 ± 1.045
0.0HisPhe: 0.0 ± 0.0
0.714HisGly: 0.714 ± 0.9
0.357HisHis: 0.357 ± 0.187
1.07HisIle: 1.07 ± 0.741
1.784HisLys: 1.784 ± 1.073
3.924HisLeu: 3.924 ± 1.571
0.357HisMet: 0.357 ± 0.187
1.07HisAsn: 1.07 ± 0.487
0.714HisPro: 0.714 ± 0.374
0.0HisGln: 0.0 ± 0.0
0.714HisArg: 0.714 ± 0.77
3.211HisSer: 3.211 ± 1.172
0.714HisThr: 0.714 ± 1.176
1.427HisVal: 1.427 ± 0.788
0.0HisTrp: 0.0 ± 0.0
1.427HisTyr: 1.427 ± 0.747
0.0HisXaa: 0.0 ± 0.0
Ile
6.065IleAla: 6.065 ± 3.265
1.784IleCys: 1.784 ± 2.425
4.281IleAsp: 4.281 ± 1.3
4.638IleGlu: 4.638 ± 1.471
3.568IlePhe: 3.568 ± 1.597
3.924IleGly: 3.924 ± 0.898
1.07IleHis: 1.07 ± 0.825
2.497IleIle: 2.497 ± 1.617
4.638IleLys: 4.638 ± 1.298
4.638IleLeu: 4.638 ± 1.132
1.427IleMet: 1.427 ± 0.751
1.427IleAsn: 1.427 ± 0.747
1.427IlePro: 1.427 ± 0.747
1.07IleGln: 1.07 ± 0.487
3.924IleArg: 3.924 ± 2.105
3.211IleSer: 3.211 ± 1.019
3.211IleThr: 3.211 ± 1.453
4.995IleVal: 4.995 ± 2.275
0.0IleTrp: 0.0 ± 0.0
1.784IleTyr: 1.784 ± 0.934
0.0IleXaa: 0.0 ± 0.0
Lys
3.924LysAla: 3.924 ± 0.693
1.427LysCys: 1.427 ± 0.747
2.854LysAsp: 2.854 ± 0.895
3.924LysGlu: 3.924 ± 0.858
2.141LysPhe: 2.141 ± 0.687
4.281LysGly: 4.281 ± 1.883
2.141LysHis: 2.141 ± 1.121
0.714LysIle: 0.714 ± 0.374
5.351LysLys: 5.351 ± 1.649
9.633LysLeu: 9.633 ± 1.285
0.357LysMet: 0.357 ± 0.187
1.07LysAsn: 1.07 ± 0.517
2.854LysPro: 2.854 ± 1.03
2.141LysGln: 2.141 ± 1.033
4.638LysArg: 4.638 ± 0.96
4.638LysSer: 4.638 ± 1.559
4.638LysThr: 4.638 ± 1.99
4.281LysVal: 4.281 ± 0.87
0.357LysTrp: 0.357 ± 0.692
2.497LysTyr: 2.497 ± 0.584
0.0LysXaa: 0.0 ± 0.0
Leu
4.638LeuAla: 4.638 ± 1.35
2.854LeuCys: 2.854 ± 1.041
4.638LeuAsp: 4.638 ± 0.564
5.351LeuGlu: 5.351 ± 1.232
4.281LeuPhe: 4.281 ± 1.749
5.708LeuGly: 5.708 ± 1.091
1.784LeuHis: 1.784 ± 0.934
10.703LeuIle: 10.703 ± 3.621
7.849LeuLys: 7.849 ± 2.048
6.422LeuLeu: 6.422 ± 0.608
1.784LeuMet: 1.784 ± 0.934
6.778LeuAsn: 6.778 ± 2.071
5.708LeuPro: 5.708 ± 2.42
1.427LeuGln: 1.427 ± 1.408
5.351LeuArg: 5.351 ± 1.255
6.778LeuSer: 6.778 ± 2.099
6.778LeuThr: 6.778 ± 1.727
2.854LeuVal: 2.854 ± 1.495
0.357LeuTrp: 0.357 ± 0.187
1.427LeuTyr: 1.427 ± 0.747
0.0LeuXaa: 0.0 ± 0.0
Met
2.141MetAla: 2.141 ± 0.687
2.141MetCys: 2.141 ± 0.592
1.427MetAsp: 1.427 ± 1.802
1.07MetGlu: 1.07 ± 0.561
0.0MetPhe: 0.0 ± 0.0
0.357MetGly: 0.357 ± 0.692
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
1.427MetLys: 1.427 ± 0.515
2.141MetLeu: 2.141 ± 0.687
0.357MetMet: 0.357 ± 0.187
0.714MetAsn: 0.714 ± 0.374
1.784MetPro: 1.784 ± 0.795
1.07MetGln: 1.07 ± 0.561
1.427MetArg: 1.427 ± 0.747
1.427MetSer: 1.427 ± 0.759
0.714MetThr: 0.714 ± 0.374
0.357MetVal: 0.357 ± 0.187
0.714MetTrp: 0.714 ± 1.387
0.357MetTyr: 0.357 ± 0.692
0.0MetXaa: 0.0 ± 0.0
Asn
2.141AsnAla: 2.141 ± 0.687
2.497AsnCys: 2.497 ± 1.51
1.07AsnAsp: 1.07 ± 0.561
3.568AsnGlu: 3.568 ± 1.359
3.568AsnPhe: 3.568 ± 1.317
3.211AsnGly: 3.211 ± 0.828
1.427AsnHis: 1.427 ± 0.81
1.07AsnIle: 1.07 ± 1.561
0.714AsnLys: 0.714 ± 0.374
6.065AsnLeu: 6.065 ± 1.936
0.357AsnMet: 0.357 ± 0.187
2.141AsnAsn: 2.141 ± 1.61
1.427AsnPro: 1.427 ± 1.408
1.07AsnGln: 1.07 ± 0.741
3.211AsnArg: 3.211 ± 1.143
3.211AsnSer: 3.211 ± 1.221
2.497AsnThr: 2.497 ± 1.015
2.141AsnVal: 2.141 ± 1.033
1.07AsnTrp: 1.07 ± 0.805
2.854AsnTyr: 2.854 ± 1.143
0.0AsnXaa: 0.0 ± 0.0
Pro
1.784ProAla: 1.784 ± 1.084
2.141ProCys: 2.141 ± 0.974
3.568ProAsp: 3.568 ± 0.789
2.854ProGlu: 2.854 ± 0.538
1.427ProPhe: 1.427 ± 0.747
2.141ProGly: 2.141 ± 0.889
1.07ProHis: 1.07 ± 1.897
2.141ProIle: 2.141 ± 0.742
3.211ProLys: 3.211 ± 1.079
2.141ProLeu: 2.141 ± 0.765
0.714ProMet: 0.714 ± 1.288
1.784ProAsn: 1.784 ± 1.073
2.141ProPro: 2.141 ± 1.355
0.714ProGln: 0.714 ± 0.374
2.854ProArg: 2.854 ± 1.041
3.924ProSer: 3.924 ± 1.48
3.568ProThr: 3.568 ± 1.594
1.784ProVal: 1.784 ± 2.067
1.427ProTrp: 1.427 ± 0.747
0.714ProTyr: 0.714 ± 0.374
0.0ProXaa: 0.0 ± 0.0
Gln
1.07GlnAla: 1.07 ± 1.562
1.427GlnCys: 1.427 ± 0.788
1.427GlnAsp: 1.427 ± 1.045
1.07GlnGlu: 1.07 ± 0.561
1.07GlnPhe: 1.07 ± 1.091
0.714GlnGly: 0.714 ± 0.77
1.427GlnHis: 1.427 ± 0.747
1.427GlnIle: 1.427 ± 1.401
1.427GlnLys: 1.427 ± 0.747
3.211GlnLeu: 3.211 ± 1.143
0.0GlnMet: 0.0 ± 0.0
1.07GlnAsn: 1.07 ± 0.487
1.427GlnPro: 1.427 ± 1.163
0.357GlnGln: 0.357 ± 0.84
0.357GlnArg: 0.357 ± 0.84
3.568GlnSer: 3.568 ± 0.797
0.714GlnThr: 0.714 ± 0.374
0.357GlnVal: 0.357 ± 0.187
0.0GlnTrp: 0.0 ± 0.0
1.07GlnTyr: 1.07 ± 1.265
0.0GlnXaa: 0.0 ± 0.0
Arg
3.211ArgAla: 3.211 ± 1.726
3.568ArgCys: 3.568 ± 2.226
4.281ArgAsp: 4.281 ± 0.989
3.924ArgGlu: 3.924 ± 0.693
4.638ArgPhe: 4.638 ± 1.031
6.422ArgGly: 6.422 ± 2.28
1.07ArgHis: 1.07 ± 0.487
1.07ArgIle: 1.07 ± 0.487
1.784ArgLys: 1.784 ± 1.252
3.568ArgLeu: 3.568 ± 1.275
1.427ArgMet: 1.427 ± 0.747
3.211ArgAsn: 3.211 ± 0.828
1.427ArgPro: 1.427 ± 1.408
0.357ArgGln: 0.357 ± 0.84
3.568ArgArg: 3.568 ± 1.826
2.141ArgSer: 2.141 ± 0.879
3.211ArgThr: 3.211 ± 2.475
4.995ArgVal: 4.995 ± 2.254
1.07ArgTrp: 1.07 ± 0.561
3.568ArgTyr: 3.568 ± 1.317
0.0ArgXaa: 0.0 ± 0.0
Ser
3.568SerAla: 3.568 ± 1.77
2.497SerCys: 2.497 ± 1.234
2.854SerAsp: 2.854 ± 0.955
5.708SerGlu: 5.708 ± 1.306
4.638SerPhe: 4.638 ± 1.423
4.995SerGly: 4.995 ± 1.056
1.427SerHis: 1.427 ± 0.521
5.351SerIle: 5.351 ± 0.785
6.422SerLys: 6.422 ± 2.286
3.568SerLeu: 3.568 ± 1.317
1.427SerMet: 1.427 ± 0.515
4.995SerAsn: 4.995 ± 2.497
2.141SerPro: 2.141 ± 0.844
2.497SerGln: 2.497 ± 0.825
4.995SerArg: 4.995 ± 1.782
6.422SerSer: 6.422 ± 2.66
6.065SerThr: 6.065 ± 1.468
3.924SerVal: 3.924 ± 0.911
0.0SerTrp: 0.0 ± 0.0
3.568SerTyr: 3.568 ± 1.485
0.0SerXaa: 0.0 ± 0.0
Thr
4.281ThrAla: 4.281 ± 1.483
1.427ThrCys: 1.427 ± 0.521
1.427ThrAsp: 1.427 ± 1.454
2.854ThrGlu: 2.854 ± 0.968
6.422ThrPhe: 6.422 ± 1.973
4.638ThrGly: 4.638 ± 2.139
2.497ThrHis: 2.497 ± 0.825
3.924ThrIle: 3.924 ± 0.898
3.568ThrLys: 3.568 ± 1.013
4.281ThrLeu: 4.281 ± 1.658
0.714ThrMet: 0.714 ± 1.513
2.497ThrAsn: 2.497 ± 0.825
2.854ThrPro: 2.854 ± 0.941
0.357ThrGln: 0.357 ± 0.692
5.351ThrArg: 5.351 ± 5.184
6.778ThrSer: 6.778 ± 0.994
1.784ThrThr: 1.784 ± 0.989
1.784ThrVal: 1.784 ± 1.424
0.357ThrTrp: 0.357 ± 0.187
1.07ThrTyr: 1.07 ± 0.561
0.0ThrXaa: 0.0 ± 0.0
Val
4.281ValAla: 4.281 ± 2.585
1.427ValCys: 1.427 ± 0.515
3.924ValAsp: 3.924 ± 0.869
3.568ValGlu: 3.568 ± 0.797
1.427ValPhe: 1.427 ± 0.661
2.141ValGly: 2.141 ± 0.765
0.714ValHis: 0.714 ± 0.374
3.568ValIle: 3.568 ± 1.69
2.497ValLys: 2.497 ± 1.282
7.492ValLeu: 7.492 ± 2.026
1.427ValMet: 1.427 ± 1.163
3.211ValAsn: 3.211 ± 1.195
3.211ValPro: 3.211 ± 0.96
1.427ValGln: 1.427 ± 0.747
2.497ValArg: 2.497 ± 0.891
3.924ValSer: 3.924 ± 1.471
3.924ValThr: 3.924 ± 0.838
5.351ValVal: 5.351 ± 1.49
0.357ValTrp: 0.357 ± 0.692
1.784ValTyr: 1.784 ± 1.67
0.0ValXaa: 0.0 ± 0.0
Trp
0.357TrpAla: 0.357 ± 0.187
0.357TrpCys: 0.357 ± 0.187
0.357TrpAsp: 0.357 ± 0.692
0.357TrpGlu: 0.357 ± 0.615
1.427TrpPhe: 1.427 ± 0.747
0.357TrpGly: 0.357 ± 0.187
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.714TrpLys: 0.714 ± 0.374
1.427TrpLeu: 1.427 ± 0.747
0.0TrpMet: 0.0 ± 0.0
0.714TrpAsn: 0.714 ± 0.374
0.0TrpPro: 0.0 ± 0.0
1.07TrpGln: 1.07 ± 1.265
0.714TrpArg: 0.714 ± 1.384
0.0TrpSer: 0.0 ± 0.0
0.357TrpThr: 0.357 ± 0.949
0.714TrpVal: 0.714 ± 0.9
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.141TyrAla: 2.141 ± 1.613
1.427TyrCys: 1.427 ± 0.992
2.141TyrAsp: 2.141 ± 1.121
1.784TyrGlu: 1.784 ± 0.934
0.357TyrPhe: 0.357 ± 0.187
1.427TyrGly: 1.427 ± 0.759
0.714TyrHis: 0.714 ± 1.68
2.141TyrIle: 2.141 ± 0.857
1.427TyrLys: 1.427 ± 0.747
4.281TyrLeu: 4.281 ± 1.632
1.427TyrMet: 1.427 ± 0.515
1.427TyrAsn: 1.427 ± 0.747
1.784TyrPro: 1.784 ± 0.934
0.357TyrGln: 0.357 ± 0.187
2.497TyrArg: 2.497 ± 2.057
2.497TyrSer: 2.497 ± 0.825
2.141TyrThr: 2.141 ± 0.473
1.784TyrVal: 1.784 ± 0.543
0.357TyrTrp: 0.357 ± 0.187
0.714TyrTyr: 0.714 ± 0.374
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (2804 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski