Amino acid dipepetide frequency for Candidatus Ornithobacterium hominis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	4.138AlaAla: 4.138 ± 0.114	0.529AlaCys: 0.529 ± 0.031	3.281AlaAsp: 3.281 ± 0.074	4.961AlaGlu: 4.961 ± 0.113	3.039AlaPhe: 3.039 ± 0.081	4.201AlaGly: 4.201 ± 0.106	1.255AlaHis: 1.255 ± 0.049	4.819AlaIle: 4.819 ± 0.121	5.112AlaLys: 5.112 ± 0.096	6.174AlaLeu: 6.174 ± 0.118	1.588AlaMet: 1.588 ± 0.052	3.248AlaAsn: 3.248 ± 0.085	1.776AlaPro: 1.776 ± 0.06	3.124AlaGln: 3.124 ± 0.064	2.204AlaArg: 2.204 ± 0.059	3.612AlaSer: 3.612 ± 0.086	3.031AlaThr: 3.031 ± 0.069	3.881AlaVal: 3.881 ± 0.098	0.675AlaTrp: 0.675 ± 0.034	2.56AlaTyr: 2.56 ± 0.07	0.0AlaXaa: 0.0 ± 0.0
Cys	0.434CysAla: 0.434 ± 0.03	0.085CysCys: 0.085 ± 0.012	0.299CysAsp: 0.299 ± 0.024	0.425CysGlu: 0.425 ± 0.024	0.382CysPhe: 0.382 ± 0.025	0.533CysGly: 0.533 ± 0.033	0.191CysHis: 0.191 ± 0.021	0.519CysIle: 0.519 ± 0.035	0.375CysLys: 0.375 ± 0.029	0.594CysLeu: 0.594 ± 0.033	0.141CysMet: 0.141 ± 0.016	0.319CysAsn: 0.319 ± 0.026	0.349CysPro: 0.349 ± 0.034	0.245CysGln: 0.245 ± 0.022	0.257CysArg: 0.257 ± 0.024	0.444CysSer: 0.444 ± 0.029	0.363CysThr: 0.363 ± 0.031	0.422CysVal: 0.422 ± 0.028	0.069CysTrp: 0.069 ± 0.012	0.238CysTyr: 0.238 ± 0.02	0.0CysXaa: 0.0 ± 0.0
Asp	3.244AspAla: 3.244 ± 0.076	0.319AspCys: 0.319 ± 0.023	2.425AspAsp: 2.425 ± 0.075	4.463AspGlu: 4.463 ± 0.092	4.034AspPhe: 4.034 ± 0.088	3.036AspGly: 3.036 ± 0.088	0.677AspHis: 0.677 ± 0.035	3.767AspIle: 3.767 ± 0.093	4.046AspLys: 4.046 ± 0.093	5.749AspLeu: 5.749 ± 0.111	1.0AspMet: 1.0 ± 0.042	2.534AspAsn: 2.534 ± 0.073	1.557AspPro: 1.557 ± 0.061	1.397AspGln: 1.397 ± 0.05	1.849AspArg: 1.849 ± 0.062	2.854AspSer: 2.854 ± 0.085	2.168AspThr: 2.168 ± 0.068	3.166AspVal: 3.166 ± 0.083	0.792AspTrp: 0.792 ± 0.042	2.77AspTyr: 2.77 ± 0.071	0.0AspXaa: 0.0 ± 0.0
Glu	4.445GluAla: 4.445 ± 0.102	0.316GluCys: 0.316 ± 0.023	3.517GluAsp: 3.517 ± 0.083	5.942GluGlu: 5.942 ± 0.145	3.388GluPhe: 3.388 ± 0.087	3.515GluGly: 3.515 ± 0.083	1.186GluHis: 1.186 ± 0.049	7.268GluIle: 7.268 ± 0.123	7.867GluLys: 7.867 ± 0.149	6.429GluLeu: 6.429 ± 0.121	1.786GluMet: 1.786 ± 0.061	6.223GluAsn: 6.223 ± 0.114	1.68GluPro: 1.68 ± 0.063	2.491GluGln: 2.491 ± 0.073	2.92GluArg: 2.92 ± 0.08	3.367GluSer: 3.367 ± 0.071	3.237GluThr: 3.237 ± 0.078	4.156GluVal: 4.156 ± 0.087	0.698GluTrp: 0.698 ± 0.034	2.415GluTyr: 2.415 ± 0.067	0.0GluXaa: 0.0 ± 0.0
Phe	2.953PheAla: 2.953 ± 0.075	0.444PheCys: 0.444 ± 0.028	3.149PheAsp: 3.149 ± 0.075	3.513PheGlu: 3.513 ± 0.083	3.076PhePhe: 3.076 ± 0.089	3.529PheGly: 3.529 ± 0.082	1.081PheHis: 1.081 ± 0.042	4.26PheIle: 4.26 ± 0.118	3.678PheLys: 3.678 ± 0.097	5.461PheLeu: 5.461 ± 0.128	1.196PheMet: 1.196 ± 0.042	3.154PheAsn: 3.154 ± 0.086	1.85PhePro: 1.85 ± 0.057	1.857PheGln: 1.857 ± 0.065	1.817PheArg: 1.817 ± 0.056	4.239PheSer: 4.239 ± 0.097	2.871PheThr: 2.871 ± 0.072	2.861PheVal: 2.861 ± 0.08	0.644PheTrp: 0.644 ± 0.034	2.395PheTyr: 2.395 ± 0.067	0.0PheXaa: 0.0 ± 0.0
Gly	3.996GlyAla: 3.996 ± 0.108	0.493GlyCys: 0.493 ± 0.034	3.114GlyAsp: 3.114 ± 0.089	4.324GlyGlu: 4.324 ± 0.088	3.567GlyPhe: 3.567 ± 0.084	4.504GlyGly: 4.504 ± 0.109	1.094GlyHis: 1.094 ± 0.047	5.282GlyIle: 5.282 ± 0.113	5.404GlyLys: 5.404 ± 0.103	5.707GlyLeu: 5.707 ± 0.11	1.524GlyMet: 1.524 ± 0.054	3.602GlyAsn: 3.602 ± 0.108	1.168GlyPro: 1.168 ± 0.047	1.864GlyGln: 1.864 ± 0.059	2.3GlyArg: 2.3 ± 0.082	3.637GlySer: 3.637 ± 0.089	3.185GlyThr: 3.185 ± 0.077	4.055GlyVal: 4.055 ± 0.097	0.722GlyTrp: 0.722 ± 0.042	2.73GlyTyr: 2.73 ± 0.078	0.0GlyXaa: 0.0 ± 0.0
His	1.064HisAla: 1.064 ± 0.044	0.156HisCys: 0.156 ± 0.017	0.816HisAsp: 0.816 ± 0.036	1.09HisGlu: 1.09 ± 0.049	1.255HisPhe: 1.255 ± 0.053	1.095HisGly: 1.095 ± 0.042	0.552HisHis: 0.552 ± 0.035	1.305HisIle: 1.305 ± 0.047	1.111HisLys: 1.111 ± 0.048	2.111HisLeu: 2.111 ± 0.06	0.354HisMet: 0.354 ± 0.023	0.847HisAsn: 0.847 ± 0.043	0.981HisPro: 0.981 ± 0.046	1.17HisGln: 1.17 ± 0.053	0.809HisArg: 0.809 ± 0.041	1.187HisSer: 1.187 ± 0.046	0.88HisThr: 0.88 ± 0.044	0.925HisVal: 0.925 ± 0.04	0.267HisTrp: 0.267 ± 0.02	0.899HisTyr: 0.899 ± 0.036	0.0HisXaa: 0.0 ± 0.0
Ile	5.135IleAla: 5.135 ± 0.106	0.588IleCys: 0.588 ± 0.035	4.541IleAsp: 4.541 ± 0.094	5.817IleGlu: 5.817 ± 0.113	4.411IlePhe: 4.411 ± 0.091	4.688IleGly: 4.688 ± 0.112	1.595IleHis: 1.595 ± 0.057	6.159IleIle: 6.159 ± 0.134	6.022IleLys: 6.022 ± 0.106	7.797IleLeu: 7.797 ± 0.162	1.323IleMet: 1.323 ± 0.06	4.635IleAsn: 4.635 ± 0.094	3.454IlePro: 3.454 ± 0.081	3.69IleGln: 3.69 ± 0.08	2.696IleArg: 2.696 ± 0.073	5.808IleSer: 5.808 ± 0.111	3.893IleThr: 3.893 ± 0.083	3.968IleVal: 3.968 ± 0.11	0.651IleTrp: 0.651 ± 0.036	2.998IleTyr: 2.998 ± 0.078	0.0IleXaa: 0.0 ± 0.0
Lys	5.174LysAla: 5.174 ± 0.087	0.345LysCys: 0.345 ± 0.025	4.312LysAsp: 4.312 ± 0.094	6.693LysGlu: 6.693 ± 0.131	3.604LysPhe: 3.604 ± 0.084	4.631LysGly: 4.631 ± 0.098	1.295LysHis: 1.295 ± 0.052	7.891LysIle: 7.891 ± 0.126	8.15LysLys: 8.15 ± 0.145	6.527LysLeu: 6.527 ± 0.114	2.014LysMet: 2.014 ± 0.061	6.862LysAsn: 6.862 ± 0.106	2.59LysPro: 2.59 ± 0.07	2.543LysGln: 2.543 ± 0.067	2.791LysArg: 2.791 ± 0.069	4.772LysSer: 4.772 ± 0.092	4.199LysThr: 4.199 ± 0.094	4.317LysVal: 4.317 ± 0.092	0.684LysTrp: 0.684 ± 0.037	3.072LysTyr: 3.072 ± 0.075	0.0LysXaa: 0.0 ± 0.0
Leu	6.266LeuAla: 6.266 ± 0.143	0.562LeuCys: 0.562 ± 0.032	4.883LeuAsp: 4.883 ± 0.091	6.579LeuGlu: 6.579 ± 0.124	4.787LeuPhe: 4.787 ± 0.114	6.195LeuGly: 6.195 ± 0.14	1.802LeuHis: 1.802 ± 0.06	7.12LeuIle: 7.12 ± 0.131	8.412LeuLys: 8.412 ± 0.138	8.509LeuLeu: 8.509 ± 0.179	2.185LeuMet: 2.185 ± 0.058	6.417LeuAsn: 6.417 ± 0.108	3.796LeuPro: 3.796 ± 0.075	3.624LeuGln: 3.624 ± 0.082	3.404LeuArg: 3.404 ± 0.072	6.761LeuSer: 6.761 ± 0.104	4.345LeuThr: 4.345 ± 0.092	5.01LeuVal: 5.01 ± 0.102	0.835LeuTrp: 0.835 ± 0.042	3.178LeuTyr: 3.178 ± 0.069	0.0LeuXaa: 0.0 ± 0.0
Met	1.562MetAla: 1.562 ± 0.061	0.111MetCys: 0.111 ± 0.013	0.996MetAsp: 0.996 ± 0.049	1.462MetGlu: 1.462 ± 0.056	0.802MetPhe: 0.802 ± 0.04	1.432MetGly: 1.432 ± 0.057	0.399MetHis: 0.399 ± 0.028	1.606MetIle: 1.606 ± 0.051	2.272MetLys: 2.272 ± 0.061	1.974MetLeu: 1.974 ± 0.061	0.606MetMet: 0.606 ± 0.035	1.458MetAsn: 1.458 ± 0.052	0.871MetPro: 0.871 ± 0.039	0.908MetGln: 0.908 ± 0.039	1.038MetArg: 1.038 ± 0.048	1.269MetSer: 1.269 ± 0.044	0.988MetThr: 0.988 ± 0.038	1.212MetVal: 1.212 ± 0.051	0.191MetTrp: 0.191 ± 0.021	0.627MetTyr: 0.627 ± 0.035	0.0MetXaa: 0.0 ± 0.0
Asn	3.845AsnAla: 3.845 ± 0.092	0.377AsnCys: 0.377 ± 0.027	2.859AsnAsp: 2.859 ± 0.084	3.973AsnGlu: 3.973 ± 0.088	3.866AsnPhe: 3.866 ± 0.103	3.774AsnGly: 3.774 ± 0.09	1.331AsnHis: 1.331 ± 0.051	5.015AsnIle: 5.015 ± 0.098	4.31AsnLys: 4.31 ± 0.106	6.391AsnLeu: 6.391 ± 0.12	1.121AsnMet: 1.121 ± 0.044	3.479AsnAsn: 3.479 ± 0.105	2.982AsnPro: 2.982 ± 0.067	3.47AsnGln: 3.47 ± 0.091	2.191AsnArg: 2.191 ± 0.07	3.571AsnSer: 3.571 ± 0.091	2.876AsnThr: 2.876 ± 0.079	3.218AsnVal: 3.218 ± 0.076	0.755AsnTrp: 0.755 ± 0.037	2.958AsnTyr: 2.958 ± 0.088	0.0AsnXaa: 0.0 ± 0.0
Pro	2.003ProAla: 2.003 ± 0.072	0.26ProCys: 0.26 ± 0.021	1.842ProAsp: 1.842 ± 0.06	2.973ProGlu: 2.973 ± 0.078	1.833ProPhe: 1.833 ± 0.062	1.885ProGly: 1.885 ± 0.064	0.79ProHis: 0.79 ± 0.045	2.638ProIle: 2.638 ± 0.068	2.736ProLys: 2.736 ± 0.081	3.032ProLeu: 3.032 ± 0.071	0.795ProMet: 0.795 ± 0.034	2.128ProAsn: 2.128 ± 0.059	0.922ProPro: 0.922 ± 0.051	1.613ProGln: 1.613 ± 0.051	1.128ProArg: 1.128 ± 0.044	2.196ProSer: 2.196 ± 0.067	1.857ProThr: 1.857 ± 0.058	2.253ProVal: 2.253 ± 0.06	0.328ProTrp: 0.328 ± 0.025	1.541ProTyr: 1.541 ± 0.055	0.0ProXaa: 0.0 ± 0.0
Gln	2.599GlnAla: 2.599 ± 0.074	0.22GlnCys: 0.22 ± 0.018	1.847GlnAsp: 1.847 ± 0.052	3.1GlnGlu: 3.1 ± 0.076	1.687GlnPhe: 1.687 ± 0.054	2.092GlnGly: 2.092 ± 0.06	0.752GlnHis: 0.752 ± 0.038	3.21GlnIle: 3.21 ± 0.076	4.109GlnLys: 4.109 ± 0.097	3.671GlnLeu: 3.671 ± 0.079	1.078GlnMet: 1.078 ± 0.045	3.015GlnAsn: 3.015 ± 0.077	1.33GlnPro: 1.33 ± 0.047	1.882GlnGln: 1.882 ± 0.073	1.68GlnArg: 1.68 ± 0.054	2.222GlnSer: 2.222 ± 0.069	1.812GlnThr: 1.812 ± 0.052	2.199GlnVal: 2.199 ± 0.059	0.469GlnTrp: 0.469 ± 0.028	1.409GlnTyr: 1.409 ± 0.052	0.0GlnXaa: 0.0 ± 0.0
Arg	2.284ArgAla: 2.284 ± 0.061	0.222ArgCys: 0.222 ± 0.02	1.873ArgAsp: 1.873 ± 0.057	2.727ArgGlu: 2.727 ± 0.066	2.008ArgPhe: 2.008 ± 0.061	2.194ArgGly: 2.194 ± 0.068	0.627ArgHis: 0.627 ± 0.038	2.868ArgIle: 2.868 ± 0.068	3.093ArgLys: 3.093 ± 0.073	3.586ArgLeu: 3.586 ± 0.084	0.962ArgMet: 0.962 ± 0.039	2.468ArgAsn: 2.468 ± 0.064	1.165ArgPro: 1.165 ± 0.048	1.265ArgGln: 1.265 ± 0.051	1.545ArgArg: 1.545 ± 0.059	1.838ArgSer: 1.838 ± 0.054	1.573ArgThr: 1.573 ± 0.056	2.196ArgVal: 2.196 ± 0.061	0.434ArgTrp: 0.434 ± 0.026	1.611ArgTyr: 1.611 ± 0.062	0.0ArgXaa: 0.0 ± 0.0
Ser	3.991SerAla: 3.991 ± 0.083	0.594SerCys: 0.594 ± 0.035	3.295SerAsp: 3.295 ± 0.086	3.958SerGlu: 3.958 ± 0.085	3.626SerPhe: 3.626 ± 0.085	4.277SerGly: 4.277 ± 0.099	1.118SerHis: 1.118 ± 0.043	4.966SerIle: 4.966 ± 0.105	4.515SerLys: 4.515 ± 0.093	6.218SerLeu: 6.218 ± 0.132	1.153SerMet: 1.153 ± 0.052	3.005SerAsn: 3.005 ± 0.076	2.328SerPro: 2.328 ± 0.071	2.421SerGln: 2.421 ± 0.068	2.062SerArg: 2.062 ± 0.067	4.031SerSer: 4.031 ± 0.098	3.104SerThr: 3.104 ± 0.078	3.788SerVal: 3.788 ± 0.078	0.686SerTrp: 0.686 ± 0.039	2.572SerTyr: 2.572 ± 0.073	0.0SerXaa: 0.0 ± 0.0
Thr	3.177ThrAla: 3.177 ± 0.074	0.304ThrCys: 0.304 ± 0.024	2.609ThrAsp: 2.609 ± 0.069	3.418ThrGlu: 3.418 ± 0.074	2.388ThrPhe: 2.388 ± 0.066	3.576ThrGly: 3.576 ± 0.078	1.01ThrHis: 1.01 ± 0.044	3.426ThrIle: 3.426 ± 0.074	3.308ThrLys: 3.308 ± 0.064	4.64ThrLeu: 4.64 ± 0.093	0.831ThrMet: 0.831 ± 0.034	2.597ThrAsn: 2.597 ± 0.075	2.328ThrPro: 2.328 ± 0.064	2.201ThrGln: 2.201 ± 0.065	1.64ThrArg: 1.64 ± 0.052	3.079ThrSer: 3.079 ± 0.07	2.493ThrThr: 2.493 ± 0.067	2.562ThrVal: 2.562 ± 0.073	0.545ThrTrp: 0.545 ± 0.032	2.022ThrTyr: 2.022 ± 0.059	0.0ThrXaa: 0.0 ± 0.0
Val	3.748ValAla: 3.748 ± 0.108	0.398ValCys: 0.398 ± 0.026	3.361ValAsp: 3.361 ± 0.092	4.162ValGlu: 4.162 ± 0.1	3.097ValPhe: 3.097 ± 0.083	3.786ValGly: 3.786 ± 0.086	0.944ValHis: 0.944 ± 0.045	4.383ValIle: 4.383 ± 0.088	4.249ValLys: 4.249 ± 0.078	5.136ValLeu: 5.136 ± 0.101	1.199ValMet: 1.199 ± 0.045	3.274ValAsn: 3.274 ± 0.084	1.979ValPro: 1.979 ± 0.071	1.949ValGln: 1.949 ± 0.055	2.05ValArg: 2.05 ± 0.054	3.673ValSer: 3.673 ± 0.088	2.694ValThr: 2.694 ± 0.067	3.583ValVal: 3.583 ± 0.1	0.514ValTrp: 0.514 ± 0.031	2.199ValTyr: 2.199 ± 0.061	0.0ValXaa: 0.0 ± 0.0
Trp	0.703TrpAla: 0.703 ± 0.035	0.099TrpCys: 0.099 ± 0.014	0.608TrpAsp: 0.608 ± 0.028	0.765TrpGlu: 0.765 ± 0.034	0.575TrpPhe: 0.575 ± 0.03	0.684TrpGly: 0.684 ± 0.037	0.203TrpHis: 0.203 ± 0.021	0.651TrpIle: 0.651 ± 0.04	0.771TrpLys: 0.771 ± 0.037	0.993TrpLeu: 0.993 ± 0.044	0.273TrpMet: 0.273 ± 0.021	0.668TrpAsn: 0.668 ± 0.033	0.241TrpPro: 0.241 ± 0.022	0.545TrpGln: 0.545 ± 0.031	0.46TrpArg: 0.46 ± 0.034	0.554TrpSer: 0.554 ± 0.033	0.455TrpThr: 0.455 ± 0.028	0.776TrpVal: 0.776 ± 0.039	0.163TrpTrp: 0.163 ± 0.017	0.429TrpTyr: 0.429 ± 0.03	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.449TyrAla: 2.449 ± 0.071	0.259TyrCys: 0.259 ± 0.021	2.224TyrAsp: 2.224 ± 0.075	2.5TyrGlu: 2.5 ± 0.072	2.604TyrPhe: 2.604 ± 0.087	2.645TyrGly: 2.645 ± 0.072	0.974TyrHis: 0.974 ± 0.046	2.717TyrIle: 2.717 ± 0.069	2.927TyrLys: 2.927 ± 0.086	3.972TyrLeu: 3.972 ± 0.087	0.653TyrMet: 0.653 ± 0.033	2.428TyrAsn: 2.428 ± 0.082	1.408TyrPro: 1.408 ± 0.052	2.121TyrGln: 2.121 ± 0.073	1.698TyrArg: 1.698 ± 0.051	2.592TyrSer: 2.592 ± 0.077	2.133TyrThr: 2.133 ± 0.066	1.831TyrVal: 1.831 ± 0.058	0.493TyrTrp: 0.493 ± 0.033	1.941TyrTyr: 1.941 ± 0.078	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 1744 proteins (576101 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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