Amino acid dipepetide frequency for Candidatus Pantoea edessiphila

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.854AlaAla: 3.854 ± 0.166
0.74AlaCys: 0.74 ± 0.063
2.31AlaAsp: 2.31 ± 0.099
2.736AlaGlu: 2.736 ± 0.122
1.91AlaPhe: 1.91 ± 0.108
3.511AlaGly: 3.511 ± 0.113
1.001AlaHis: 1.001 ± 0.067
6.26AlaIle: 6.26 ± 0.186
4.063AlaLys: 4.063 ± 0.134
5.881AlaLeu: 5.881 ± 0.182
1.57AlaMet: 1.57 ± 0.075
3.067AlaAsn: 3.067 ± 0.125
1.379AlaPro: 1.379 ± 0.088
1.718AlaGln: 1.718 ± 0.095
2.558AlaArg: 2.558 ± 0.116
3.219AlaSer: 3.219 ± 0.126
2.558AlaThr: 2.558 ± 0.117
3.163AlaVal: 3.163 ± 0.13
0.531AlaTrp: 0.531 ± 0.051
1.662AlaTyr: 1.662 ± 0.087
0.0AlaXaa: 0.0 ± 0.0
Cys
0.718CysAla: 0.718 ± 0.057
0.248CysCys: 0.248 ± 0.031
0.735CysAsp: 0.735 ± 0.064
0.631CysGlu: 0.631 ± 0.049
0.648CysPhe: 0.648 ± 0.052
1.027CysGly: 1.027 ± 0.063
0.344CysHis: 0.344 ± 0.047
1.44CysIle: 1.44 ± 0.089
0.931CysLys: 0.931 ± 0.064
1.301CysLeu: 1.301 ± 0.074
0.322CysMet: 0.322 ± 0.03
1.044CysAsn: 1.044 ± 0.065
0.479CysPro: 0.479 ± 0.048
0.457CysGln: 0.457 ± 0.041
0.505CysArg: 0.505 ± 0.049
1.061CysSer: 1.061 ± 0.063
0.626CysThr: 0.626 ± 0.052
0.666CysVal: 0.666 ± 0.054
0.139CysTrp: 0.139 ± 0.024
0.552CysTyr: 0.552 ± 0.044
0.0CysXaa: 0.0 ± 0.0
Asp
2.279AspAla: 2.279 ± 0.116
0.726AspCys: 0.726 ± 0.062
1.853AspAsp: 1.853 ± 0.088
2.145AspGlu: 2.145 ± 0.109
2.375AspPhe: 2.375 ± 0.105
2.323AspGly: 2.323 ± 0.108
1.014AspHis: 1.014 ± 0.066
5.799AspIle: 5.799 ± 0.152
3.645AspLys: 3.645 ± 0.136
4.972AspLeu: 4.972 ± 0.142
1.175AspMet: 1.175 ± 0.071
3.184AspAsn: 3.184 ± 0.129
1.418AspPro: 1.418 ± 0.085
1.462AspGln: 1.462 ± 0.073
2.066AspArg: 2.066 ± 0.09
2.788AspSer: 2.788 ± 0.112
2.145AspThr: 2.145 ± 0.077
2.671AspVal: 2.671 ± 0.1
0.631AspTrp: 0.631 ± 0.056
1.91AspTyr: 1.91 ± 0.104
0.0AspXaa: 0.0 ± 0.0
Glu
2.897GluAla: 2.897 ± 0.129
0.552GluCys: 0.552 ± 0.045
2.258GluAsp: 2.258 ± 0.106
2.845GluGlu: 2.845 ± 0.127
2.018GluPhe: 2.018 ± 0.093
2.475GluGly: 2.475 ± 0.111
1.001GluHis: 1.001 ± 0.065
6.251GluIle: 6.251 ± 0.167
4.463GluLys: 4.463 ± 0.153
5.238GluLeu: 5.238 ± 0.167
1.266GluMet: 1.266 ± 0.072
3.484GluAsn: 3.484 ± 0.113
1.266GluPro: 1.266 ± 0.076
1.992GluGln: 1.992 ± 0.091
2.519GluArg: 2.519 ± 0.124
3.054GluSer: 3.054 ± 0.121
2.279GluThr: 2.279 ± 0.113
2.945GluVal: 2.945 ± 0.137
0.426GluTrp: 0.426 ± 0.046
1.753GluTyr: 1.753 ± 0.095
0.0GluXaa: 0.0 ± 0.0
Phe
1.905PheAla: 1.905 ± 0.098
0.809PheCys: 0.809 ± 0.064
2.406PheAsp: 2.406 ± 0.114
1.966PheGlu: 1.966 ± 0.103
1.984PhePhe: 1.984 ± 0.109
2.715PheGly: 2.715 ± 0.101
0.909PheHis: 0.909 ± 0.054
4.681PheIle: 4.681 ± 0.172
2.693PheLys: 2.693 ± 0.092
3.793PheLeu: 3.793 ± 0.16
0.987PheMet: 0.987 ± 0.066
3.28PheAsn: 3.28 ± 0.138
1.483PhePro: 1.483 ± 0.083
1.288PheGln: 1.288 ± 0.082
1.562PheArg: 1.562 ± 0.076
3.319PheSer: 3.319 ± 0.152
2.136PheThr: 2.136 ± 0.104
2.171PheVal: 2.171 ± 0.097
0.487PheTrp: 0.487 ± 0.058
1.597PheTyr: 1.597 ± 0.077
0.0PheXaa: 0.0 ± 0.0
Gly
3.358GlyAla: 3.358 ± 0.14
1.07GlyCys: 1.07 ± 0.059
2.68GlyAsp: 2.68 ± 0.108
2.658GlyGlu: 2.658 ± 0.122
2.928GlyPhe: 2.928 ± 0.111
3.937GlyGly: 3.937 ± 0.149
1.27GlyHis: 1.27 ± 0.075
7.086GlyIle: 7.086 ± 0.202
4.537GlyLys: 4.537 ± 0.134
5.516GlyLeu: 5.516 ± 0.172
1.549GlyMet: 1.549 ± 0.073
3.258GlyAsn: 3.258 ± 0.142
1.566GlyPro: 1.566 ± 0.091
1.836GlyGln: 1.836 ± 0.094
2.554GlyArg: 2.554 ± 0.135
3.541GlySer: 3.541 ± 0.114
3.006GlyThr: 3.006 ± 0.127
3.615GlyVal: 3.615 ± 0.135
0.609GlyTrp: 0.609 ± 0.055
2.388GlyTyr: 2.388 ± 0.097
0.0GlyXaa: 0.0 ± 0.0
His
1.079HisAla: 1.079 ± 0.072
0.396HisCys: 0.396 ± 0.04
0.97HisAsp: 0.97 ± 0.069
0.905HisGlu: 0.905 ± 0.062
0.931HisPhe: 0.931 ± 0.066
1.518HisGly: 1.518 ± 0.09
0.574HisHis: 0.574 ± 0.046
2.219HisIle: 2.219 ± 0.098
1.588HisLys: 1.588 ± 0.088
2.119HisLeu: 2.119 ± 0.083
0.509HisMet: 0.509 ± 0.046
1.544HisAsn: 1.544 ± 0.079
1.127HisPro: 1.127 ± 0.084
0.787HisGln: 0.787 ± 0.055
0.909HisArg: 0.909 ± 0.063
1.383HisSer: 1.383 ± 0.088
0.957HisThr: 0.957 ± 0.06
1.053HisVal: 1.053 ± 0.064
0.318HisTrp: 0.318 ± 0.036
0.848HisTyr: 0.848 ± 0.063
0.0HisXaa: 0.0 ± 0.0
Ile
6.691IleAla: 6.691 ± 0.198
1.462IleCys: 1.462 ± 0.077
6.147IleAsp: 6.147 ± 0.169
6.39IleGlu: 6.39 ± 0.185
4.359IlePhe: 4.359 ± 0.168
6.939IleGly: 6.939 ± 0.219
2.14IleHis: 2.14 ± 0.087
11.615IleIle: 11.615 ± 0.266
8.983IleLys: 8.983 ± 0.243
10.201IleLeu: 10.201 ± 0.27
2.279IleMet: 2.279 ± 0.098
9.509IleAsn: 9.509 ± 0.243
4.281IlePro: 4.281 ± 0.134
3.267IleGln: 3.267 ± 0.115
4.368IleArg: 4.368 ± 0.146
7.996IleSer: 7.996 ± 0.17
5.89IleThr: 5.89 ± 0.153
5.612IleVal: 5.612 ± 0.152
1.009IleTrp: 1.009 ± 0.067
3.463IleTyr: 3.463 ± 0.123
0.0IleXaa: 0.0 ± 0.0
Lys
3.532LysAla: 3.532 ± 0.14
0.692LysCys: 0.692 ± 0.059
3.458LysAsp: 3.458 ± 0.14
4.376LysGlu: 4.376 ± 0.145
2.932LysPhe: 2.932 ± 0.115
3.637LysGly: 3.637 ± 0.131
1.679LysHis: 1.679 ± 0.078
9.701LysIle: 9.701 ± 0.208
7.078LysLys: 7.078 ± 0.202
8.178LysLeu: 8.178 ± 0.21
1.923LysMet: 1.923 ± 0.088
6.808LysAsn: 6.808 ± 0.224
2.271LysPro: 2.271 ± 0.099
3.028LysGln: 3.028 ± 0.125
3.093LysArg: 3.093 ± 0.123
4.663LysSer: 4.663 ± 0.139
3.833LysThr: 3.833 ± 0.142
3.467LysVal: 3.467 ± 0.144
0.683LysTrp: 0.683 ± 0.056
3.154LysTyr: 3.154 ± 0.135
0.0LysXaa: 0.0 ± 0.0
Leu
5.812LeuAla: 5.812 ± 0.186
1.309LeuCys: 1.309 ± 0.071
4.485LeuAsp: 4.485 ± 0.146
5.151LeuGlu: 5.151 ± 0.167
4.15LeuPhe: 4.15 ± 0.153
5.821LeuGly: 5.821 ± 0.183
2.414LeuHis: 2.414 ± 0.114
10.801LeuIle: 10.801 ± 0.269
7.926LeuLys: 7.926 ± 0.2
9.897LeuLeu: 9.897 ± 0.287
2.432LeuMet: 2.432 ± 0.122
7.152LeuAsn: 7.152 ± 0.179
4.067LeuPro: 4.067 ± 0.131
3.397LeuGln: 3.397 ± 0.105
4.559LeuArg: 4.559 ± 0.143
7.339LeuSer: 7.339 ± 0.202
4.994LeuThr: 4.994 ± 0.147
5.538LeuVal: 5.538 ± 0.165
0.905LeuTrp: 0.905 ± 0.063
3.171LeuTyr: 3.171 ± 0.118
0.0LeuXaa: 0.0 ± 0.0
Met
1.475MetAla: 1.475 ± 0.082
0.27MetCys: 0.27 ± 0.032
0.848MetAsp: 0.848 ± 0.061
1.005MetGlu: 1.005 ± 0.071
0.9MetPhe: 0.9 ± 0.067
1.47MetGly: 1.47 ± 0.085
0.544MetHis: 0.544 ± 0.046
2.545MetIle: 2.545 ± 0.115
1.84MetLys: 1.84 ± 0.092
2.628MetLeu: 2.628 ± 0.097
0.6MetMet: 0.6 ± 0.055
1.736MetAsn: 1.736 ± 0.088
0.935MetPro: 0.935 ± 0.071
1.022MetGln: 1.022 ± 0.065
1.088MetArg: 1.088 ± 0.073
1.692MetSer: 1.692 ± 0.092
1.122MetThr: 1.122 ± 0.073
1.296MetVal: 1.296 ± 0.068
0.191MetTrp: 0.191 ± 0.03
0.7MetTyr: 0.7 ± 0.053
0.0MetXaa: 0.0 ± 0.0
Asn
3.058AsnAla: 3.058 ± 0.133
0.983AsnCys: 0.983 ± 0.071
3.289AsnAsp: 3.289 ± 0.146
3.454AsnGlu: 3.454 ± 0.14
3.084AsnPhe: 3.084 ± 0.139
3.167AsnGly: 3.167 ± 0.122
1.601AsnHis: 1.601 ± 0.076
9.183AsnIle: 9.183 ± 0.23
6.591AsnLys: 6.591 ± 0.2
6.882AsnLeu: 6.882 ± 0.184
1.753AsnMet: 1.753 ± 0.083
6.377AsnAsn: 6.377 ± 0.223
2.597AsnPro: 2.597 ± 0.135
2.91AsnGln: 2.91 ± 0.128
2.932AsnArg: 2.932 ± 0.107
4.485AsnSer: 4.485 ± 0.166
3.297AsnThr: 3.297 ± 0.143
3.141AsnVal: 3.141 ± 0.13
0.9AsnTrp: 0.9 ± 0.07
2.815AsnTyr: 2.815 ± 0.119
0.0AsnXaa: 0.0 ± 0.0
Pro
1.527ProAla: 1.527 ± 0.069
0.405ProCys: 0.405 ± 0.034
1.583ProAsp: 1.583 ± 0.087
2.123ProGlu: 2.123 ± 0.11
1.518ProPhe: 1.518 ± 0.077
2.162ProGly: 2.162 ± 0.1
0.709ProHis: 0.709 ± 0.056
3.924ProIle: 3.924 ± 0.145
2.262ProLys: 2.262 ± 0.091
3.276ProLeu: 3.276 ± 0.119
0.748ProMet: 0.748 ± 0.056
2.458ProAsn: 2.458 ± 0.157
0.866ProPro: 0.866 ± 0.065
0.979ProGln: 0.979 ± 0.064
1.118ProArg: 1.118 ± 0.068
2.14ProSer: 2.14 ± 0.103
1.644ProThr: 1.644 ± 0.093
2.149ProVal: 2.149 ± 0.092
0.348ProTrp: 0.348 ± 0.046
1.318ProTyr: 1.318 ± 0.082
0.0ProXaa: 0.0 ± 0.0
Gln
1.971GlnAla: 1.971 ± 0.103
0.396GlnCys: 0.396 ± 0.044
1.462GlnAsp: 1.462 ± 0.08
1.91GlnGlu: 1.91 ± 0.094
1.288GlnPhe: 1.288 ± 0.079
2.001GlnGly: 2.001 ± 0.079
0.779GlnHis: 0.779 ± 0.055
3.767GlnIle: 3.767 ± 0.129
2.81GlnLys: 2.81 ± 0.126
4.063GlnLeu: 4.063 ± 0.132
0.818GlnMet: 0.818 ± 0.054
2.223GlnAsn: 2.223 ± 0.102
1.044GlnPro: 1.044 ± 0.061
1.388GlnGln: 1.388 ± 0.087
1.396GlnArg: 1.396 ± 0.066
2.001GlnSer: 2.001 ± 0.105
1.431GlnThr: 1.431 ± 0.073
1.884GlnVal: 1.884 ± 0.085
0.278GlnTrp: 0.278 ± 0.034
1.418GlnTyr: 1.418 ± 0.083
0.0GlnXaa: 0.0 ± 0.0
Arg
2.21ArgAla: 2.21 ± 0.122
0.622ArgCys: 0.622 ± 0.053
1.897ArgAsp: 1.897 ± 0.107
2.419ArgGlu: 2.419 ± 0.105
1.979ArgPhe: 1.979 ± 0.09
2.384ArgGly: 2.384 ± 0.104
0.918ArgHis: 0.918 ± 0.071
4.511ArgIle: 4.511 ± 0.161
3.136ArgLys: 3.136 ± 0.121
4.281ArgLeu: 4.281 ± 0.156
1.018ArgMet: 1.018 ± 0.078
2.823ArgAsn: 2.823 ± 0.123
1.353ArgPro: 1.353 ± 0.076
1.605ArgGln: 1.605 ± 0.088
2.053ArgArg: 2.053 ± 0.111
2.593ArgSer: 2.593 ± 0.1
1.818ArgThr: 1.818 ± 0.1
2.34ArgVal: 2.34 ± 0.113
0.487ArgTrp: 0.487 ± 0.056
1.757ArgTyr: 1.757 ± 0.083
0.0ArgXaa: 0.0 ± 0.0
Ser
3.271SerAla: 3.271 ± 0.12
0.957SerCys: 0.957 ± 0.067
3.089SerAsp: 3.089 ± 0.147
3.176SerGlu: 3.176 ± 0.131
2.941SerPhe: 2.941 ± 0.116
4.407SerGly: 4.407 ± 0.171
1.336SerHis: 1.336 ± 0.084
7.408SerIle: 7.408 ± 0.196
4.781SerLys: 4.781 ± 0.15
7.182SerLeu: 7.182 ± 0.233
1.54SerMet: 1.54 ± 0.081
4.737SerAsn: 4.737 ± 0.162
1.705SerPro: 1.705 ± 0.095
2.062SerGln: 2.062 ± 0.085
2.684SerArg: 2.684 ± 0.105
4.607SerSer: 4.607 ± 0.157
3.215SerThr: 3.215 ± 0.115
3.511SerVal: 3.511 ± 0.12
0.748SerTrp: 0.748 ± 0.058
2.353SerTyr: 2.353 ± 0.095
0.0SerXaa: 0.0 ± 0.0
Thr
2.719ThrAla: 2.719 ± 0.12
0.674ThrCys: 0.674 ± 0.053
2.275ThrAsp: 2.275 ± 0.112
2.362ThrGlu: 2.362 ± 0.119
1.927ThrPhe: 1.927 ± 0.1
3.376ThrGly: 3.376 ± 0.124
1.005ThrHis: 1.005 ± 0.06
5.051ThrIle: 5.051 ± 0.154
3.532ThrLys: 3.532 ± 0.134
5.246ThrLeu: 5.246 ± 0.167
1.031ThrMet: 1.031 ± 0.061
3.032ThrAsn: 3.032 ± 0.111
1.871ThrPro: 1.871 ± 0.082
1.488ThrGln: 1.488 ± 0.071
1.966ThrArg: 1.966 ± 0.086
3.132ThrSer: 3.132 ± 0.116
2.527ThrThr: 2.527 ± 0.104
2.941ThrVal: 2.941 ± 0.105
0.431ThrTrp: 0.431 ± 0.05
1.47ThrTyr: 1.47 ± 0.073
0.0ThrXaa: 0.0 ± 0.0
Val
3.158ValAla: 3.158 ± 0.141
0.757ValCys: 0.757 ± 0.061
2.701ValAsp: 2.701 ± 0.114
2.741ValGlu: 2.741 ± 0.13
2.127ValPhe: 2.127 ± 0.095
3.402ValGly: 3.402 ± 0.122
1.148ValHis: 1.148 ± 0.073
5.834ValIle: 5.834 ± 0.166
3.967ValLys: 3.967 ± 0.142
5.499ValLeu: 5.499 ± 0.179
1.375ValMet: 1.375 ± 0.077
3.498ValAsn: 3.498 ± 0.104
1.84ValPro: 1.84 ± 0.098
1.536ValGln: 1.536 ± 0.086
2.223ValArg: 2.223 ± 0.11
3.593ValSer: 3.593 ± 0.121
2.597ValThr: 2.597 ± 0.104
3.267ValVal: 3.267 ± 0.137
0.518ValTrp: 0.518 ± 0.049
1.801ValTyr: 1.801 ± 0.086
0.0ValXaa: 0.0 ± 0.0
Trp
0.435TrpAla: 0.435 ± 0.044
0.178TrpCys: 0.178 ± 0.03
0.361TrpAsp: 0.361 ± 0.041
0.392TrpGlu: 0.392 ± 0.036
0.535TrpPhe: 0.535 ± 0.056
0.439TrpGly: 0.439 ± 0.043
0.361TrpHis: 0.361 ± 0.045
1.118TrpIle: 1.118 ± 0.082
0.835TrpLys: 0.835 ± 0.062
1.305TrpLeu: 1.305 ± 0.098
0.27TrpMet: 0.27 ± 0.034
0.783TrpAsn: 0.783 ± 0.06
0.339TrpPro: 0.339 ± 0.043
0.492TrpGln: 0.492 ± 0.052
0.439TrpArg: 0.439 ± 0.047
0.574TrpSer: 0.574 ± 0.053
0.4TrpThr: 0.4 ± 0.044
0.439TrpVal: 0.439 ± 0.046
0.109TrpTrp: 0.109 ± 0.021
0.439TrpTyr: 0.439 ± 0.05
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.74TyrAla: 1.74 ± 0.09
0.626TyrCys: 0.626 ± 0.054
1.775TyrAsp: 1.775 ± 0.076
1.601TyrGlu: 1.601 ± 0.098
1.636TyrPhe: 1.636 ± 0.093
2.253TyrGly: 2.253 ± 0.112
0.987TyrHis: 0.987 ± 0.068
3.406TyrIle: 3.406 ± 0.119
2.523TyrLys: 2.523 ± 0.12
3.863TyrLeu: 3.863 ± 0.139
0.74TyrMet: 0.74 ± 0.059
2.501TyrAsn: 2.501 ± 0.102
1.37TyrPro: 1.37 ± 0.084
1.614TyrGln: 1.614 ± 0.091
1.618TyrArg: 1.618 ± 0.079
2.527TyrSer: 2.527 ± 0.109
1.579TyrThr: 1.579 ± 0.082
1.714TyrVal: 1.714 ± 0.085
0.496TyrTrp: 0.496 ± 0.049
1.54TyrTyr: 1.54 ± 0.093
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 689 proteins (229877 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski