Amino acid dipepetide frequency for Wenzhou picorna-like virus 48

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.122AlaAla: 4.122 ± 0.0
1.268AlaCys: 1.268 ± 0.0
3.171AlaAsp: 3.171 ± 0.0
2.219AlaGlu: 2.219 ± 0.0
2.854AlaPhe: 2.854 ± 0.0
4.756AlaGly: 4.756 ± 0.0
1.268AlaHis: 1.268 ± 0.0
5.073AlaIle: 5.073 ± 0.0
2.536AlaLys: 2.536 ± 0.0
5.073AlaLeu: 5.073 ± 0.0
1.585AlaMet: 1.585 ± 0.0
1.902AlaAsn: 1.902 ± 0.0
2.219AlaPro: 2.219 ± 0.0
1.268AlaGln: 1.268 ± 0.0
2.219AlaArg: 2.219 ± 0.0
6.024AlaSer: 6.024 ± 0.0
2.536AlaThr: 2.536 ± 0.0
3.171AlaVal: 3.171 ± 0.0
0.317AlaTrp: 0.317 ± 0.0
3.171AlaTyr: 3.171 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
0.317CysAla: 0.317 ± 0.0
0.317CysCys: 0.317 ± 0.0
0.951CysAsp: 0.951 ± 0.0
1.902CysGlu: 1.902 ± 0.0
2.219CysPhe: 2.219 ± 0.0
1.585CysGly: 1.585 ± 0.0
0.951CysHis: 0.951 ± 0.0
1.268CysIle: 1.268 ± 0.0
1.902CysLys: 1.902 ± 0.0
1.268CysLeu: 1.268 ± 0.0
0.951CysMet: 0.951 ± 0.0
1.268CysAsn: 1.268 ± 0.0
0.951CysPro: 0.951 ± 0.0
0.317CysGln: 0.317 ± 0.0
0.634CysArg: 0.634 ± 0.0
1.268CysSer: 1.268 ± 0.0
0.951CysThr: 0.951 ± 0.0
1.585CysVal: 1.585 ± 0.0
1.268CysTrp: 1.268 ± 0.0
1.585CysTyr: 1.585 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.219AspAla: 2.219 ± 0.0
1.902AspCys: 1.902 ± 0.0
3.488AspAsp: 3.488 ± 0.0
5.073AspGlu: 5.073 ± 0.0
4.756AspPhe: 4.756 ± 0.0
3.171AspGly: 3.171 ± 0.0
1.268AspHis: 1.268 ± 0.0
3.171AspIle: 3.171 ± 0.0
2.536AspLys: 2.536 ± 0.0
2.854AspLeu: 2.854 ± 0.0
0.634AspMet: 0.634 ± 0.0
3.171AspAsn: 3.171 ± 0.0
1.585AspPro: 1.585 ± 0.0
3.171AspGln: 3.171 ± 0.0
1.585AspArg: 1.585 ± 0.0
2.536AspSer: 2.536 ± 0.0
3.171AspThr: 3.171 ± 0.0
6.341AspVal: 6.341 ± 0.0
0.317AspTrp: 0.317 ± 0.0
3.488AspTyr: 3.488 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
2.854GluAla: 2.854 ± 0.0
2.219GluCys: 2.219 ± 0.0
3.805GluAsp: 3.805 ± 0.0
5.707GluGlu: 5.707 ± 0.0
2.854GluPhe: 2.854 ± 0.0
3.171GluGly: 3.171 ± 0.0
2.219GluHis: 2.219 ± 0.0
5.39GluIle: 5.39 ± 0.0
4.122GluLys: 4.122 ± 0.0
4.122GluLeu: 4.122 ± 0.0
2.219GluMet: 2.219 ± 0.0
2.854GluAsn: 2.854 ± 0.0
1.902GluPro: 1.902 ± 0.0
3.171GluGln: 3.171 ± 0.0
3.488GluArg: 3.488 ± 0.0
4.122GluSer: 4.122 ± 0.0
3.805GluThr: 3.805 ± 0.0
4.439GluVal: 4.439 ± 0.0
1.585GluTrp: 1.585 ± 0.0
1.902GluTyr: 1.902 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
2.536PheAla: 2.536 ± 0.0
0.317PheCys: 0.317 ± 0.0
2.854PheAsp: 2.854 ± 0.0
4.122PheGlu: 4.122 ± 0.0
2.536PhePhe: 2.536 ± 0.0
2.219PheGly: 2.219 ± 0.0
2.536PheHis: 2.536 ± 0.0
2.854PheIle: 2.854 ± 0.0
2.854PheLys: 2.854 ± 0.0
3.171PheLeu: 3.171 ± 0.0
1.902PheMet: 1.902 ± 0.0
3.171PheAsn: 3.171 ± 0.0
1.902PhePro: 1.902 ± 0.0
3.171PheGln: 3.171 ± 0.0
2.854PheArg: 2.854 ± 0.0
3.171PheSer: 3.171 ± 0.0
2.536PheThr: 2.536 ± 0.0
2.854PheVal: 2.854 ± 0.0
1.268PheTrp: 1.268 ± 0.0
1.902PheTyr: 1.902 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
4.756GlyAla: 4.756 ± 0.0
1.902GlyCys: 1.902 ± 0.0
3.171GlyAsp: 3.171 ± 0.0
5.707GlyGlu: 5.707 ± 0.0
4.756GlyPhe: 4.756 ± 0.0
1.902GlyGly: 1.902 ± 0.0
0.634GlyHis: 0.634 ± 0.0
4.122GlyIle: 4.122 ± 0.0
4.756GlyLys: 4.756 ± 0.0
2.854GlyLeu: 2.854 ± 0.0
0.951GlyMet: 0.951 ± 0.0
2.219GlyAsn: 2.219 ± 0.0
2.854GlyPro: 2.854 ± 0.0
2.854GlyGln: 2.854 ± 0.0
2.219GlyArg: 2.219 ± 0.0
6.341GlySer: 6.341 ± 0.0
4.439GlyThr: 4.439 ± 0.0
4.122GlyVal: 4.122 ± 0.0
0.0GlyTrp: 0.0 ± 0.0
2.219GlyTyr: 2.219 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
2.219HisAla: 2.219 ± 0.0
0.317HisCys: 0.317 ± 0.0
1.902HisAsp: 1.902 ± 0.0
0.951HisGlu: 0.951 ± 0.0
0.951HisPhe: 0.951 ± 0.0
2.536HisGly: 2.536 ± 0.0
0.0HisHis: 0.0 ± 0.0
0.634HisIle: 0.634 ± 0.0
2.536HisLys: 2.536 ± 0.0
3.171HisLeu: 3.171 ± 0.0
0.317HisMet: 0.317 ± 0.0
0.634HisAsn: 0.634 ± 0.0
1.268HisPro: 1.268 ± 0.0
1.268HisGln: 1.268 ± 0.0
1.585HisArg: 1.585 ± 0.0
1.268HisSer: 1.268 ± 0.0
1.585HisThr: 1.585 ± 0.0
1.585HisVal: 1.585 ± 0.0
0.951HisTrp: 0.951 ± 0.0
0.951HisTyr: 0.951 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
3.488IleAla: 3.488 ± 0.0
1.902IleCys: 1.902 ± 0.0
2.854IleAsp: 2.854 ± 0.0
4.439IleGlu: 4.439 ± 0.0
1.902IlePhe: 1.902 ± 0.0
4.122IleGly: 4.122 ± 0.0
1.268IleHis: 1.268 ± 0.0
2.219IleIle: 2.219 ± 0.0
3.805IleLys: 3.805 ± 0.0
3.488IleLeu: 3.488 ± 0.0
0.951IleMet: 0.951 ± 0.0
2.854IleAsn: 2.854 ± 0.0
4.439IlePro: 4.439 ± 0.0
3.488IleGln: 3.488 ± 0.0
2.536IleArg: 2.536 ± 0.0
4.756IleSer: 4.756 ± 0.0
3.805IleThr: 3.805 ± 0.0
3.171IleVal: 3.171 ± 0.0
0.0IleTrp: 0.0 ± 0.0
3.171IleTyr: 3.171 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
1.585LysAla: 1.585 ± 0.0
0.951LysCys: 0.951 ± 0.0
2.536LysAsp: 2.536 ± 0.0
6.341LysGlu: 6.341 ± 0.0
0.951LysPhe: 0.951 ± 0.0
1.902LysGly: 1.902 ± 0.0
2.536LysHis: 2.536 ± 0.0
3.805LysIle: 3.805 ± 0.0
5.39LysLys: 5.39 ± 0.0
4.122LysLeu: 4.122 ± 0.0
1.268LysMet: 1.268 ± 0.0
2.854LysAsn: 2.854 ± 0.0
2.219LysPro: 2.219 ± 0.0
0.634LysGln: 0.634 ± 0.0
3.805LysArg: 3.805 ± 0.0
3.488LysSer: 3.488 ± 0.0
4.756LysThr: 4.756 ± 0.0
5.707LysVal: 5.707 ± 0.0
0.634LysTrp: 0.634 ± 0.0
4.439LysTyr: 4.439 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
4.439LeuAla: 4.439 ± 0.0
1.268LeuCys: 1.268 ± 0.0
8.244LeuAsp: 8.244 ± 0.0
2.536LeuGlu: 2.536 ± 0.0
4.439LeuPhe: 4.439 ± 0.0
5.39LeuGly: 5.39 ± 0.0
1.902LeuHis: 1.902 ± 0.0
3.488LeuIle: 3.488 ± 0.0
4.756LeuLys: 4.756 ± 0.0
7.926LeuLeu: 7.926 ± 0.0
2.854LeuMet: 2.854 ± 0.0
1.268LeuAsn: 1.268 ± 0.0
4.439LeuPro: 4.439 ± 0.0
1.902LeuGln: 1.902 ± 0.0
3.171LeuArg: 3.171 ± 0.0
6.658LeuSer: 6.658 ± 0.0
5.073LeuThr: 5.073 ± 0.0
3.171LeuVal: 3.171 ± 0.0
0.634LeuTrp: 0.634 ± 0.0
5.39LeuTyr: 5.39 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
2.219MetAla: 2.219 ± 0.0
0.951MetCys: 0.951 ± 0.0
1.585MetAsp: 1.585 ± 0.0
0.951MetGlu: 0.951 ± 0.0
1.585MetPhe: 1.585 ± 0.0
1.268MetGly: 1.268 ± 0.0
0.317MetHis: 0.317 ± 0.0
0.317MetIle: 0.317 ± 0.0
1.585MetLys: 1.585 ± 0.0
2.219MetLeu: 2.219 ± 0.0
0.317MetMet: 0.317 ± 0.0
0.634MetAsn: 0.634 ± 0.0
1.902MetPro: 1.902 ± 0.0
0.951MetGln: 0.951 ± 0.0
0.634MetArg: 0.634 ± 0.0
1.268MetSer: 1.268 ± 0.0
1.585MetThr: 1.585 ± 0.0
0.951MetVal: 0.951 ± 0.0
0.0MetTrp: 0.0 ± 0.0
1.268MetTyr: 1.268 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.854AsnAla: 2.854 ± 0.0
0.634AsnCys: 0.634 ± 0.0
0.634AsnAsp: 0.634 ± 0.0
2.536AsnGlu: 2.536 ± 0.0
3.171AsnPhe: 3.171 ± 0.0
1.902AsnGly: 1.902 ± 0.0
0.634AsnHis: 0.634 ± 0.0
1.902AsnIle: 1.902 ± 0.0
2.536AsnLys: 2.536 ± 0.0
3.805AsnLeu: 3.805 ± 0.0
0.634AsnMet: 0.634 ± 0.0
2.219AsnAsn: 2.219 ± 0.0
3.488AsnPro: 3.488 ± 0.0
1.585AsnGln: 1.585 ± 0.0
2.536AsnArg: 2.536 ± 0.0
3.171AsnSer: 3.171 ± 0.0
1.902AsnThr: 1.902 ± 0.0
4.756AsnVal: 4.756 ± 0.0
1.268AsnTrp: 1.268 ± 0.0
1.902AsnTyr: 1.902 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
1.902ProAla: 1.902 ± 0.0
0.317ProCys: 0.317 ± 0.0
3.488ProAsp: 3.488 ± 0.0
2.219ProGlu: 2.219 ± 0.0
1.268ProPhe: 1.268 ± 0.0
3.171ProGly: 3.171 ± 0.0
0.951ProHis: 0.951 ± 0.0
2.536ProIle: 2.536 ± 0.0
3.488ProLys: 3.488 ± 0.0
5.073ProLeu: 5.073 ± 0.0
1.268ProMet: 1.268 ± 0.0
1.268ProAsn: 1.268 ± 0.0
4.756ProPro: 4.756 ± 0.0
1.902ProGln: 1.902 ± 0.0
1.585ProArg: 1.585 ± 0.0
4.439ProSer: 4.439 ± 0.0
2.536ProThr: 2.536 ± 0.0
4.122ProVal: 4.122 ± 0.0
0.317ProTrp: 0.317 ± 0.0
2.219ProTyr: 2.219 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
2.219GlnAla: 2.219 ± 0.0
0.634GlnCys: 0.634 ± 0.0
1.268GlnAsp: 1.268 ± 0.0
2.219GlnGlu: 2.219 ± 0.0
1.902GlnPhe: 1.902 ± 0.0
3.805GlnGly: 3.805 ± 0.0
1.268GlnHis: 1.268 ± 0.0
1.902GlnIle: 1.902 ± 0.0
1.902GlnLys: 1.902 ± 0.0
3.805GlnLeu: 3.805 ± 0.0
0.317GlnMet: 0.317 ± 0.0
1.268GlnAsn: 1.268 ± 0.0
2.536GlnPro: 2.536 ± 0.0
0.951GlnGln: 0.951 ± 0.0
2.219GlnArg: 2.219 ± 0.0
3.488GlnSer: 3.488 ± 0.0
1.585GlnThr: 1.585 ± 0.0
1.902GlnVal: 1.902 ± 0.0
0.951GlnTrp: 0.951 ± 0.0
1.585GlnTyr: 1.585 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
3.805ArgAla: 3.805 ± 0.0
1.268ArgCys: 1.268 ± 0.0
1.902ArgAsp: 1.902 ± 0.0
4.756ArgGlu: 4.756 ± 0.0
1.585ArgPhe: 1.585 ± 0.0
2.536ArgGly: 2.536 ± 0.0
0.951ArgHis: 0.951 ± 0.0
2.854ArgIle: 2.854 ± 0.0
3.488ArgLys: 3.488 ± 0.0
4.756ArgLeu: 4.756 ± 0.0
0.317ArgMet: 0.317 ± 0.0
0.951ArgAsn: 0.951 ± 0.0
0.634ArgPro: 0.634 ± 0.0
1.902ArgGln: 1.902 ± 0.0
4.439ArgArg: 4.439 ± 0.0
3.171ArgSer: 3.171 ± 0.0
2.219ArgThr: 2.219 ± 0.0
4.122ArgVal: 4.122 ± 0.0
0.0ArgTrp: 0.0 ± 0.0
1.585ArgTyr: 1.585 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
5.073SerAla: 5.073 ± 0.0
1.902SerCys: 1.902 ± 0.0
5.39SerAsp: 5.39 ± 0.0
3.805SerGlu: 3.805 ± 0.0
4.122SerPhe: 4.122 ± 0.0
6.024SerGly: 6.024 ± 0.0
2.536SerHis: 2.536 ± 0.0
3.488SerIle: 3.488 ± 0.0
2.536SerLys: 2.536 ± 0.0
7.926SerLeu: 7.926 ± 0.0
1.268SerMet: 1.268 ± 0.0
3.488SerAsn: 3.488 ± 0.0
1.585SerPro: 1.585 ± 0.0
2.536SerGln: 2.536 ± 0.0
3.171SerArg: 3.171 ± 0.0
4.439SerSer: 4.439 ± 0.0
3.805SerThr: 3.805 ± 0.0
4.122SerVal: 4.122 ± 0.0
0.634SerTrp: 0.634 ± 0.0
1.902SerTyr: 1.902 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
3.488ThrAla: 3.488 ± 0.0
1.268ThrCys: 1.268 ± 0.0
2.536ThrAsp: 2.536 ± 0.0
2.536ThrGlu: 2.536 ± 0.0
2.219ThrPhe: 2.219 ± 0.0
3.171ThrGly: 3.171 ± 0.0
0.951ThrHis: 0.951 ± 0.0
3.805ThrIle: 3.805 ± 0.0
3.805ThrLys: 3.805 ± 0.0
4.439ThrLeu: 4.439 ± 0.0
1.268ThrMet: 1.268 ± 0.0
3.488ThrAsn: 3.488 ± 0.0
4.439ThrPro: 4.439 ± 0.0
1.902ThrGln: 1.902 ± 0.0
2.536ThrArg: 2.536 ± 0.0
3.488ThrSer: 3.488 ± 0.0
5.073ThrThr: 5.073 ± 0.0
4.756ThrVal: 4.756 ± 0.0
0.634ThrTrp: 0.634 ± 0.0
1.585ThrTyr: 1.585 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
2.536ValAla: 2.536 ± 0.0
2.536ValCys: 2.536 ± 0.0
3.488ValAsp: 3.488 ± 0.0
3.805ValGlu: 3.805 ± 0.0
2.854ValPhe: 2.854 ± 0.0
6.024ValGly: 6.024 ± 0.0
2.219ValHis: 2.219 ± 0.0
6.024ValIle: 6.024 ± 0.0
3.171ValLys: 3.171 ± 0.0
5.707ValLeu: 5.707 ± 0.0
0.951ValMet: 0.951 ± 0.0
5.073ValAsn: 5.073 ± 0.0
3.805ValPro: 3.805 ± 0.0
1.902ValGln: 1.902 ± 0.0
2.854ValArg: 2.854 ± 0.0
3.805ValSer: 3.805 ± 0.0
2.854ValThr: 2.854 ± 0.0
5.39ValVal: 5.39 ± 0.0
1.902ValTrp: 1.902 ± 0.0
2.536ValTyr: 2.536 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
1.268TrpAla: 1.268 ± 0.0
0.634TrpCys: 0.634 ± 0.0
0.317TrpAsp: 0.317 ± 0.0
1.268TrpGlu: 1.268 ± 0.0
0.951TrpPhe: 0.951 ± 0.0
0.634TrpGly: 0.634 ± 0.0
0.634TrpHis: 0.634 ± 0.0
1.585TrpIle: 1.585 ± 0.0
0.317TrpLys: 0.317 ± 0.0
0.0TrpLeu: 0.0 ± 0.0
0.634TrpMet: 0.634 ± 0.0
0.951TrpAsn: 0.951 ± 0.0
0.317TrpPro: 0.317 ± 0.0
0.317TrpGln: 0.317 ± 0.0
0.317TrpArg: 0.317 ± 0.0
0.634TrpSer: 0.634 ± 0.0
1.268TrpThr: 1.268 ± 0.0
0.634TrpVal: 0.634 ± 0.0
0.317TrpTrp: 0.317 ± 0.0
1.268TrpTyr: 1.268 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.854TyrAla: 2.854 ± 0.0
0.951TyrCys: 0.951 ± 0.0
2.854TyrAsp: 2.854 ± 0.0
2.854TyrGlu: 2.854 ± 0.0
2.854TyrPhe: 2.854 ± 0.0
3.488TyrGly: 3.488 ± 0.0
1.585TyrHis: 1.585 ± 0.0
2.219TyrIle: 2.219 ± 0.0
1.902TyrLys: 1.902 ± 0.0
3.171TyrLeu: 3.171 ± 0.0
1.585TyrMet: 1.585 ± 0.0
2.536TyrAsn: 2.536 ± 0.0
1.585TyrPro: 1.585 ± 0.0
2.536TyrGln: 2.536 ± 0.0
2.854TyrArg: 2.854 ± 0.0
2.219TyrSer: 2.219 ± 0.0
2.219TyrThr: 2.219 ± 0.0
2.536TyrVal: 2.536 ± 0.0
1.268TyrTrp: 1.268 ± 0.0
4.439TyrTyr: 4.439 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1 proteins (3155 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski