Amino acid dipepetide frequency for Sida mottle Alagoas virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.27AlaAla: 6.27 ± 4.514
1.045AlaCys: 1.045 ± 0.902
1.045AlaAsp: 1.045 ± 0.752
4.18AlaGlu: 4.18 ± 1.606
1.045AlaPhe: 1.045 ± 1.077
2.09AlaGly: 2.09 ± 1.805
1.045AlaHis: 1.045 ± 0.752
0.0AlaIle: 0.0 ± 0.0
6.27AlaLys: 6.27 ± 1.551
8.359AlaLeu: 8.359 ± 2.148
0.0AlaMet: 0.0 ± 0.0
0.0AlaAsn: 0.0 ± 0.0
4.18AlaPro: 4.18 ± 1.093
1.045AlaGln: 1.045 ± 0.752
5.225AlaArg: 5.225 ± 2.108
6.27AlaSer: 6.27 ± 2.015
5.225AlaThr: 5.225 ± 1.346
2.09AlaVal: 2.09 ± 1.536
1.045AlaTrp: 1.045 ± 0.752
0.0AlaTyr: 0.0 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
1.045CysGlu: 1.045 ± 0.902
0.0CysPhe: 0.0 ± 0.0
1.045CysGly: 1.045 ± 1.201
0.0CysHis: 0.0 ± 0.0
2.09CysIle: 2.09 ± 0.738
2.09CysLys: 2.09 ± 0.738
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
1.045CysAsn: 1.045 ± 0.752
1.045CysPro: 1.045 ± 1.131
2.09CysGln: 2.09 ± 1.505
1.045CysArg: 1.045 ± 0.752
3.135CysSer: 3.135 ± 1.529
4.18CysThr: 4.18 ± 2.018
1.045CysVal: 1.045 ± 0.902
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.135AspAla: 3.135 ± 1.186
2.09AspCys: 2.09 ± 1.151
6.27AspAsp: 6.27 ± 3.058
2.09AspGlu: 2.09 ± 0.738
3.135AspPhe: 3.135 ± 1.186
3.135AspGly: 3.135 ± 2.257
0.0AspHis: 0.0 ± 0.0
2.09AspIle: 2.09 ± 1.349
3.135AspLys: 3.135 ± 2.23
4.18AspLeu: 4.18 ± 2.496
1.045AspMet: 1.045 ± 0.752
2.09AspAsn: 2.09 ± 1.349
1.045AspPro: 1.045 ± 1.077
1.045AspGln: 1.045 ± 1.077
4.18AspArg: 4.18 ± 1.548
5.225AspSer: 5.225 ± 1.264
1.045AspThr: 1.045 ± 0.752
4.18AspVal: 4.18 ± 1.475
1.045AspTrp: 1.045 ± 0.752
1.045AspTyr: 1.045 ± 0.752
0.0AspXaa: 0.0 ± 0.0
Glu
4.18GluAla: 4.18 ± 1.844
0.0GluCys: 0.0 ± 0.0
1.045GluAsp: 1.045 ± 1.077
5.225GluGlu: 5.225 ± 2.212
1.045GluPhe: 1.045 ± 0.752
4.18GluGly: 4.18 ± 1.844
0.0GluHis: 0.0 ± 0.0
1.045GluIle: 1.045 ± 1.077
3.135GluLys: 3.135 ± 2.257
4.18GluLeu: 4.18 ± 1.606
1.045GluMet: 1.045 ± 0.752
7.315GluAsn: 7.315 ± 2.713
3.135GluPro: 3.135 ± 1.186
2.09GluGln: 2.09 ± 1.805
1.045GluArg: 1.045 ± 0.752
2.09GluSer: 2.09 ± 1.151
1.045GluThr: 1.045 ± 1.131
2.09GluVal: 2.09 ± 2.262
4.18GluTrp: 4.18 ± 1.021
1.045GluTyr: 1.045 ± 0.752
0.0GluXaa: 0.0 ± 0.0
Phe
1.045PheAla: 1.045 ± 1.077
2.09PheCys: 2.09 ± 0.738
2.09PheAsp: 2.09 ± 0.738
1.045PheGlu: 1.045 ± 0.752
1.045PhePhe: 1.045 ± 0.752
2.09PheGly: 2.09 ± 0.738
2.09PheHis: 2.09 ± 1.505
2.09PheIle: 2.09 ± 1.505
1.045PheLys: 1.045 ± 1.077
4.18PheLeu: 4.18 ± 2.104
0.0PheMet: 0.0 ± 0.0
4.18PheAsn: 4.18 ± 1.913
1.045PhePro: 1.045 ± 0.752
5.225PheGln: 5.225 ± 1.891
2.09PheArg: 2.09 ± 1.499
3.135PheSer: 3.135 ± 0.93
2.09PheThr: 2.09 ± 1.151
0.0PheVal: 0.0 ± 0.0
3.135PheTrp: 3.135 ± 1.955
3.135PheTyr: 3.135 ± 2.027
0.0PheXaa: 0.0 ± 0.0
Gly
4.18GlyAla: 4.18 ± 3.009
3.135GlyCys: 3.135 ± 0.93
2.09GlyAsp: 2.09 ± 1.505
5.225GlyGlu: 5.225 ± 2.108
1.045GlyPhe: 1.045 ± 1.201
3.135GlyGly: 3.135 ± 1.186
2.09GlyHis: 2.09 ± 1.151
4.18GlyIle: 4.18 ± 1.426
7.315GlyLys: 7.315 ± 2.844
1.045GlyLeu: 1.045 ± 1.077
0.0GlyMet: 0.0 ± 0.0
3.135GlyAsn: 3.135 ± 1.717
3.135GlyPro: 3.135 ± 1.467
3.135GlyGln: 3.135 ± 1.957
4.18GlyArg: 4.18 ± 2.302
4.18GlySer: 4.18 ± 2.51
4.18GlyThr: 4.18 ± 2.105
2.09GlyVal: 2.09 ± 2.154
0.0GlyTrp: 0.0 ± 0.0
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
1.045HisAla: 1.045 ± 0.902
1.045HisCys: 1.045 ± 1.201
2.09HisAsp: 2.09 ± 0.738
0.0HisGlu: 0.0 ± 0.0
1.045HisPhe: 1.045 ± 0.752
1.045HisGly: 1.045 ± 1.201
1.045HisHis: 1.045 ± 1.201
2.09HisIle: 2.09 ± 1.499
2.09HisLys: 2.09 ± 1.349
4.18HisLeu: 4.18 ± 1.428
1.045HisMet: 1.045 ± 1.018
4.18HisAsn: 4.18 ± 2.104
2.09HisPro: 2.09 ± 1.151
2.09HisGln: 2.09 ± 1.349
4.18HisArg: 4.18 ± 2.654
1.045HisSer: 1.045 ± 1.077
2.09HisThr: 2.09 ± 1.805
2.09HisVal: 2.09 ± 0.738
1.045HisTrp: 1.045 ± 0.752
1.045HisTyr: 1.045 ± 0.752
0.0HisXaa: 0.0 ± 0.0
Ile
1.045IleAla: 1.045 ± 1.201
1.045IleCys: 1.045 ± 0.752
1.045IleAsp: 1.045 ± 0.752
0.0IleGlu: 0.0 ± 0.0
2.09IlePhe: 2.09 ± 1.505
4.18IleGly: 4.18 ± 1.009
0.0IleHis: 0.0 ± 0.0
2.09IleIle: 2.09 ± 1.057
7.315IleLys: 7.315 ± 1.767
2.09IleLeu: 2.09 ± 0.738
1.045IleMet: 1.045 ± 0.902
2.09IleAsn: 2.09 ± 1.349
3.135IlePro: 3.135 ± 1.529
2.09IleGln: 2.09 ± 1.057
5.225IleArg: 5.225 ± 3.338
5.225IleSer: 5.225 ± 2.267
4.18IleThr: 4.18 ± 2.385
2.09IleVal: 2.09 ± 1.505
2.09IleTrp: 2.09 ± 1.349
4.18IleTyr: 4.18 ± 1.426
0.0IleXaa: 0.0 ± 0.0
Lys
5.225LysAla: 5.225 ± 1.606
0.0LysCys: 0.0 ± 0.0
3.135LysAsp: 3.135 ± 2.257
5.225LysGlu: 5.225 ± 3.762
5.225LysPhe: 5.225 ± 1.606
3.135LysGly: 3.135 ± 1.682
1.045LysHis: 1.045 ± 0.752
6.27LysIle: 6.27 ± 2.015
2.09LysLys: 2.09 ± 1.151
2.09LysLeu: 2.09 ± 0.738
0.0LysMet: 0.0 ± 0.0
3.135LysAsn: 3.135 ± 1.467
3.135LysPro: 3.135 ± 0.93
0.0LysGln: 0.0 ± 0.0
5.225LysArg: 5.225 ± 2.807
5.225LysSer: 5.225 ± 1.888
3.135LysThr: 3.135 ± 1.682
6.27LysVal: 6.27 ± 4.428
0.0LysTrp: 0.0 ± 0.0
3.135LysTyr: 3.135 ± 1.186
0.0LysXaa: 0.0 ± 0.0
Leu
1.045LeuAla: 1.045 ± 1.077
2.09LeuCys: 2.09 ± 1.505
7.315LeuAsp: 7.315 ± 2.603
2.09LeuGlu: 2.09 ± 1.499
3.135LeuPhe: 3.135 ± 2.23
4.18LeuGly: 4.18 ± 1.009
4.18LeuHis: 4.18 ± 2.104
4.18LeuIle: 4.18 ± 1.606
6.27LeuLys: 6.27 ± 2.371
4.18LeuLeu: 4.18 ± 1.475
1.045LeuMet: 1.045 ± 0.902
9.404LeuAsn: 9.404 ± 2.833
1.045LeuPro: 1.045 ± 1.201
3.135LeuGln: 3.135 ± 1.682
3.135LeuArg: 3.135 ± 2.027
2.09LeuSer: 2.09 ± 1.505
3.135LeuThr: 3.135 ± 1.682
3.135LeuVal: 3.135 ± 2.027
0.0LeuTrp: 0.0 ± 0.0
4.18LeuTyr: 4.18 ± 1.009
0.0LeuXaa: 0.0 ± 0.0
Met
2.09MetAla: 2.09 ± 1.805
1.045MetCys: 1.045 ± 0.902
3.135MetAsp: 3.135 ± 2.027
1.045MetGlu: 1.045 ± 0.752
2.09MetPhe: 2.09 ± 1.805
1.045MetGly: 1.045 ± 1.131
1.045MetHis: 1.045 ± 0.902
0.0MetIle: 0.0 ± 0.0
0.0MetLys: 0.0 ± 0.0
1.045MetLeu: 1.045 ± 1.201
1.045MetMet: 1.045 ± 1.077
1.045MetAsn: 1.045 ± 0.902
2.09MetPro: 2.09 ± 0.738
1.045MetGln: 1.045 ± 0.752
0.0MetArg: 0.0 ± 0.0
0.0MetSer: 0.0 ± 0.0
1.045MetThr: 1.045 ± 1.077
1.045MetVal: 1.045 ± 0.752
1.045MetTrp: 1.045 ± 0.752
2.09MetTyr: 2.09 ± 1.349
0.0MetXaa: 0.0 ± 0.0
Asn
5.225AsnAla: 5.225 ± 1.803
2.09AsnCys: 2.09 ± 1.151
3.135AsnAsp: 3.135 ± 0.93
2.09AsnGlu: 2.09 ± 1.805
3.135AsnPhe: 3.135 ± 2.269
3.135AsnGly: 3.135 ± 1.598
6.27AsnHis: 6.27 ± 3.298
2.09AsnIle: 2.09 ± 0.738
3.135AsnLys: 3.135 ± 0.93
4.18AsnLeu: 4.18 ± 2.104
1.045AsnMet: 1.045 ± 1.701
4.18AsnAsn: 4.18 ± 1.009
4.18AsnPro: 4.18 ± 1.093
2.09AsnGln: 2.09 ± 1.536
2.09AsnArg: 2.09 ± 0.738
6.27AsnSer: 6.27 ± 2.104
0.0AsnThr: 0.0 ± 0.0
3.135AsnVal: 3.135 ± 1.485
0.0AsnTrp: 0.0 ± 0.0
3.135AsnTyr: 3.135 ± 1.186
0.0AsnXaa: 0.0 ± 0.0
Pro
0.0ProAla: 0.0 ± 0.0
1.045ProCys: 1.045 ± 0.902
3.135ProAsp: 3.135 ± 0.93
4.18ProGlu: 4.18 ± 2.118
0.0ProPhe: 0.0 ± 0.0
1.045ProGly: 1.045 ± 0.752
4.18ProHis: 4.18 ± 2.118
1.045ProIle: 1.045 ± 0.752
2.09ProLys: 2.09 ± 1.805
3.135ProLeu: 3.135 ± 1.278
2.09ProMet: 2.09 ± 1.805
1.045ProAsn: 1.045 ± 0.752
3.135ProPro: 3.135 ± 1.278
5.225ProGln: 5.225 ± 3.888
7.315ProArg: 7.315 ± 1.724
5.225ProSer: 5.225 ± 1.888
3.135ProThr: 3.135 ± 2.229
3.135ProVal: 3.135 ± 1.186
3.135ProTrp: 3.135 ± 1.054
2.09ProTyr: 2.09 ± 1.349
0.0ProXaa: 0.0 ± 0.0
Gln
3.135GlnAla: 3.135 ± 0.971
1.045GlnCys: 1.045 ± 0.752
3.135GlnAsp: 3.135 ± 2.23
3.135GlnGlu: 3.135 ± 1.186
2.09GlnPhe: 2.09 ± 1.505
4.18GlnGly: 4.18 ± 2.51
2.09GlnHis: 2.09 ± 1.711
4.18GlnIle: 4.18 ± 2.104
1.045GlnLys: 1.045 ± 0.752
2.09GlnLeu: 2.09 ± 1.536
0.0GlnMet: 0.0 ± 0.0
0.0GlnAsn: 0.0 ± 0.0
2.09GlnPro: 2.09 ± 2.403
2.09GlnGln: 2.09 ± 2.262
2.09GlnArg: 2.09 ± 1.319
2.09GlnSer: 2.09 ± 0.738
2.09GlnThr: 2.09 ± 1.505
5.225GlnVal: 5.225 ± 2.227
0.0GlnTrp: 0.0 ± 0.0
1.045GlnTyr: 1.045 ± 0.902
0.0GlnXaa: 0.0 ± 0.0
Arg
5.225ArgAla: 5.225 ± 1.869
1.045ArgCys: 1.045 ± 0.752
3.135ArgAsp: 3.135 ± 2.707
3.135ArgGlu: 3.135 ± 1.565
6.27ArgPhe: 6.27 ± 3.137
6.27ArgGly: 6.27 ± 1.859
4.18ArgHis: 4.18 ± 1.876
6.27ArgIle: 6.27 ± 1.197
3.135ArgLys: 3.135 ± 1.054
3.135ArgLeu: 3.135 ± 1.717
0.0ArgMet: 0.0 ± 0.0
0.0ArgAsn: 0.0 ± 0.0
5.225ArgPro: 5.225 ± 1.426
0.0ArgGln: 0.0 ± 0.0
5.225ArgArg: 5.225 ± 3.573
6.27ArgSer: 6.27 ± 1.215
5.225ArgThr: 5.225 ± 1.96
4.18ArgVal: 4.18 ± 2.38
0.0ArgTrp: 0.0 ± 0.0
1.045ArgTyr: 1.045 ± 0.902
0.0ArgXaa: 0.0 ± 0.0
Ser
2.09SerAla: 2.09 ± 1.505
0.0SerCys: 0.0 ± 0.0
3.135SerAsp: 3.135 ± 1.186
1.045SerGlu: 1.045 ± 0.902
3.135SerPhe: 3.135 ± 1.529
4.18SerGly: 4.18 ± 1.009
1.045SerHis: 1.045 ± 0.902
7.315SerIle: 7.315 ± 3.289
3.135SerLys: 3.135 ± 1.054
6.27SerLeu: 6.27 ± 2.795
3.135SerMet: 3.135 ± 1.297
7.315SerAsn: 7.315 ± 2.01
6.27SerPro: 6.27 ± 2.045
2.09SerGln: 2.09 ± 1.505
5.225SerArg: 5.225 ± 2.062
13.584SerSer: 13.584 ± 7.077
6.27SerThr: 6.27 ± 4.17
3.135SerVal: 3.135 ± 1.955
0.0SerTrp: 0.0 ± 0.0
4.18SerTyr: 4.18 ± 1.093
0.0SerXaa: 0.0 ± 0.0
Thr
4.18ThrAla: 4.18 ± 2.385
0.0ThrCys: 0.0 ± 0.0
2.09ThrAsp: 2.09 ± 1.499
2.09ThrGlu: 2.09 ± 1.319
2.09ThrPhe: 2.09 ± 1.22
4.18ThrGly: 4.18 ± 1.009
4.18ThrHis: 4.18 ± 2.697
0.0ThrIle: 0.0 ± 0.0
2.09ThrLys: 2.09 ± 1.505
3.135ThrLeu: 3.135 ± 1.054
2.09ThrMet: 2.09 ± 1.505
4.18ThrAsn: 4.18 ± 1.093
6.27ThrPro: 6.27 ± 1.197
1.045ThrGln: 1.045 ± 0.752
4.18ThrArg: 4.18 ± 1.913
8.359ThrSer: 8.359 ± 2.988
6.27ThrThr: 6.27 ± 2.43
2.09ThrVal: 2.09 ± 1.349
1.045ThrTrp: 1.045 ± 1.131
1.045ThrTyr: 1.045 ± 1.077
0.0ThrXaa: 0.0 ± 0.0
Val
1.045ValAla: 1.045 ± 1.131
0.0ValCys: 0.0 ± 0.0
2.09ValAsp: 2.09 ± 1.151
3.135ValGlu: 3.135 ± 1.485
1.045ValPhe: 1.045 ± 0.902
2.09ValGly: 2.09 ± 1.805
1.045ValHis: 1.045 ± 1.201
3.135ValIle: 3.135 ± 1.997
4.18ValLys: 4.18 ± 2.321
4.18ValLeu: 4.18 ± 1.606
4.18ValMet: 4.18 ± 2.834
4.18ValAsn: 4.18 ± 1.548
3.135ValPro: 3.135 ± 0.93
3.135ValGln: 3.135 ± 0.93
3.135ValArg: 3.135 ± 1.607
2.09ValSer: 2.09 ± 0.738
3.135ValThr: 3.135 ± 1.467
1.045ValVal: 1.045 ± 0.902
1.045ValTrp: 1.045 ± 1.077
5.225ValTyr: 5.225 ± 3.324
0.0ValXaa: 0.0 ± 0.0
Trp
3.135TrpAla: 3.135 ± 2.257
1.045TrpCys: 1.045 ± 1.131
1.045TrpAsp: 1.045 ± 1.201
1.045TrpGlu: 1.045 ± 1.077
0.0TrpPhe: 0.0 ± 0.0
1.045TrpGly: 1.045 ± 0.752
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
2.09TrpLys: 2.09 ± 0.738
1.045TrpLeu: 1.045 ± 0.902
1.045TrpMet: 1.045 ± 0.902
1.045TrpAsn: 1.045 ± 1.131
0.0TrpPro: 0.0 ± 0.0
1.045TrpGln: 1.045 ± 0.752
2.09TrpArg: 2.09 ± 1.349
0.0TrpSer: 0.0 ± 0.0
2.09TrpThr: 2.09 ± 1.057
1.045TrpVal: 1.045 ± 0.902
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.135TyrAla: 3.135 ± 2.707
0.0TyrCys: 0.0 ± 0.0
1.045TyrAsp: 1.045 ± 0.902
2.09TyrGlu: 2.09 ± 1.805
4.18TyrPhe: 4.18 ± 1.093
2.09TyrGly: 2.09 ± 0.738
1.045TyrHis: 1.045 ± 1.077
2.09TyrIle: 2.09 ± 1.349
1.045TyrLys: 1.045 ± 0.752
6.27TyrLeu: 6.27 ± 2.233
2.09TyrMet: 2.09 ± 1.207
2.09TyrAsn: 2.09 ± 0.738
0.0TyrPro: 0.0 ± 0.0
3.135TyrGln: 3.135 ± 0.93
2.09TyrArg: 2.09 ± 1.805
1.045TyrSer: 1.045 ± 0.752
1.045TyrThr: 1.045 ± 1.077
3.135TyrVal: 3.135 ± 0.971
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (958 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski