Amino acid dipepetide frequency for Facklamia ignava CCUG 37419

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.953AlaAla: 4.953 ± 0.125
0.493AlaCys: 0.493 ± 0.037
3.509AlaAsp: 3.509 ± 0.083
4.693AlaGlu: 4.693 ± 0.098
2.77AlaPhe: 2.77 ± 0.083
4.738AlaGly: 4.738 ± 0.119
1.468AlaHis: 1.468 ± 0.058
5.898AlaIle: 5.898 ± 0.141
3.936AlaLys: 3.936 ± 0.09
7.202AlaLeu: 7.202 ± 0.155
2.25AlaMet: 2.25 ± 0.074
3.081AlaAsn: 3.081 ± 0.084
1.911AlaPro: 1.911 ± 0.07
3.379AlaGln: 3.379 ± 0.099
2.819AlaArg: 2.819 ± 0.087
4.019AlaSer: 4.019 ± 0.086
3.84AlaThr: 3.84 ± 0.085
4.525AlaVal: 4.525 ± 0.113
0.502AlaTrp: 0.502 ± 0.031
2.758AlaTyr: 2.758 ± 0.069
0.0AlaXaa: 0.0 ± 0.0
Cys
0.428CysAla: 0.428 ± 0.032
0.073CysCys: 0.073 ± 0.012
0.404CysAsp: 0.404 ± 0.03
0.362CysGlu: 0.362 ± 0.033
0.28CysPhe: 0.28 ± 0.022
0.575CysGly: 0.575 ± 0.038
0.223CysHis: 0.223 ± 0.025
0.388CysIle: 0.388 ± 0.029
0.225CysLys: 0.225 ± 0.021
0.628CysLeu: 0.628 ± 0.036
0.122CysMet: 0.122 ± 0.017
0.232CysAsn: 0.232 ± 0.023
0.307CysPro: 0.307 ± 0.027
0.327CysGln: 0.327 ± 0.024
0.264CysArg: 0.264 ± 0.025
0.357CysSer: 0.357 ± 0.031
0.264CysThr: 0.264 ± 0.021
0.433CysVal: 0.433 ± 0.03
0.047CysTrp: 0.047 ± 0.009
0.319CysTyr: 0.319 ± 0.027
0.0CysXaa: 0.0 ± 0.0
Asp
3.749AspAla: 3.749 ± 0.087
0.412AspCys: 0.412 ± 0.027
2.764AspAsp: 2.764 ± 0.082
4.787AspGlu: 4.787 ± 0.134
2.748AspPhe: 2.748 ± 0.079
3.42AspGly: 3.42 ± 0.103
1.387AspHis: 1.387 ± 0.095
4.271AspIle: 4.271 ± 0.101
2.878AspLys: 2.878 ± 0.105
5.569AspLeu: 5.569 ± 0.11
1.247AspMet: 1.247 ± 0.052
2.149AspAsn: 2.149 ± 0.065
2.106AspPro: 2.106 ± 0.076
3.247AspGln: 3.247 ± 0.085
2.502AspArg: 2.502 ± 0.07
3.134AspSer: 3.134 ± 0.079
2.736AspThr: 2.736 ± 0.076
3.593AspVal: 3.593 ± 0.099
0.688AspTrp: 0.688 ± 0.041
3.148AspTyr: 3.148 ± 0.088
0.0AspXaa: 0.0 ± 0.0
Glu
6.172GluAla: 6.172 ± 0.142
0.376GluCys: 0.376 ± 0.03
4.24GluAsp: 4.24 ± 0.117
6.753GluGlu: 6.753 ± 0.175
2.543GluPhe: 2.543 ± 0.073
4.098GluGly: 4.098 ± 0.11
1.59GluHis: 1.59 ± 0.053
5.841GluIle: 5.841 ± 0.125
4.224GluLys: 4.224 ± 0.111
7.494GluLeu: 7.494 ± 0.161
2.22GluMet: 2.22 ± 0.068
3.231GluAsn: 3.231 ± 0.088
2.224GluPro: 2.224 ± 0.082
3.873GluGln: 3.873 ± 0.112
3.946GluArg: 3.946 ± 0.104
4.275GluSer: 4.275 ± 0.103
4.052GluThr: 4.052 ± 0.111
5.648GluVal: 5.648 ± 0.112
0.703GluTrp: 0.703 ± 0.036
2.73GluTyr: 2.73 ± 0.073
0.0GluXaa: 0.0 ± 0.0
Phe
2.506PheAla: 2.506 ± 0.08
0.266PheCys: 0.266 ± 0.025
2.784PheAsp: 2.784 ± 0.067
3.044PheGlu: 3.044 ± 0.084
1.7PhePhe: 1.7 ± 0.068
2.691PheGly: 2.691 ± 0.091
0.699PheHis: 0.699 ± 0.034
3.649PheIle: 3.649 ± 0.115
2.342PheLys: 2.342 ± 0.069
3.503PheLeu: 3.503 ± 0.099
1.019PheMet: 1.019 ± 0.051
2.242PheAsn: 2.242 ± 0.058
1.377PhePro: 1.377 ± 0.052
1.47PheGln: 1.47 ± 0.046
1.397PheArg: 1.397 ± 0.047
2.565PheSer: 2.565 ± 0.076
2.279PheThr: 2.279 ± 0.079
2.679PheVal: 2.679 ± 0.08
0.362PheTrp: 0.362 ± 0.029
1.606PheTyr: 1.606 ± 0.06
0.0PheXaa: 0.0 ± 0.0
Gly
4.216GlyAla: 4.216 ± 0.118
0.455GlyCys: 0.455 ± 0.031
3.26GlyAsp: 3.26 ± 0.087
4.679GlyGlu: 4.679 ± 0.133
2.764GlyPhe: 2.764 ± 0.081
4.104GlyGly: 4.104 ± 0.127
1.369GlyHis: 1.369 ± 0.056
5.315GlyIle: 5.315 ± 0.12
3.542GlyLys: 3.542 ± 0.088
6.186GlyLeu: 6.186 ± 0.13
1.81GlyMet: 1.81 ± 0.072
2.35GlyAsn: 2.35 ± 0.078
1.548GlyPro: 1.548 ± 0.055
2.79GlyGln: 2.79 ± 0.062
2.831GlyArg: 2.831 ± 0.083
3.526GlySer: 3.526 ± 0.081
3.81GlyThr: 3.81 ± 0.1
4.73GlyVal: 4.73 ± 0.117
0.597GlyTrp: 0.597 ± 0.033
2.888GlyTyr: 2.888 ± 0.077
0.0GlyXaa: 0.0 ± 0.0
His
1.296HisAla: 1.296 ± 0.048
0.177HisCys: 0.177 ± 0.024
1.243HisAsp: 1.243 ± 0.094
1.389HisGlu: 1.389 ± 0.051
1.099HisPhe: 1.099 ± 0.044
1.308HisGly: 1.308 ± 0.057
0.82HisHis: 0.82 ± 0.044
1.576HisIle: 1.576 ± 0.051
0.849HisLys: 0.849 ± 0.036
2.445HisLeu: 2.445 ± 0.079
0.414HisMet: 0.414 ± 0.029
0.762HisAsn: 0.762 ± 0.045
1.355HisPro: 1.355 ± 0.064
1.564HisGln: 1.564 ± 0.056
1.186HisArg: 1.186 ± 0.048
1.275HisSer: 1.275 ± 0.044
1.052HisThr: 1.052 ± 0.046
1.202HisVal: 1.202 ± 0.053
0.26HisTrp: 0.26 ± 0.022
1.259HisTyr: 1.259 ± 0.054
0.0HisXaa: 0.0 ± 0.0
Ile
5.847IleAla: 5.847 ± 0.124
0.573IleCys: 0.573 ± 0.035
5.435IleAsp: 5.435 ± 0.116
6.649IleGlu: 6.649 ± 0.135
3.046IlePhe: 3.046 ± 0.104
5.437IleGly: 5.437 ± 0.137
1.816IleHis: 1.816 ± 0.065
6.46IleIle: 6.46 ± 0.141
4.013IleLys: 4.013 ± 0.098
7.12IleLeu: 7.12 ± 0.145
1.692IleMet: 1.692 ± 0.063
3.777IleAsn: 3.777 ± 0.094
3.339IlePro: 3.339 ± 0.084
4.167IleGln: 4.167 ± 0.124
3.373IleArg: 3.373 ± 0.092
4.724IleSer: 4.724 ± 0.117
4.169IleThr: 4.169 ± 0.092
5.357IleVal: 5.357 ± 0.107
0.556IleTrp: 0.556 ± 0.035
2.953IleTyr: 2.953 ± 0.078
0.0IleXaa: 0.0 ± 0.0
Lys
3.603LysAla: 3.603 ± 0.098
0.248LysCys: 0.248 ± 0.022
3.3LysAsp: 3.3 ± 0.116
4.819LysGlu: 4.819 ± 0.122
1.649LysPhe: 1.649 ± 0.06
3.02LysGly: 3.02 ± 0.089
1.074LysHis: 1.074 ± 0.047
3.92LysIle: 3.92 ± 0.096
3.099LysLys: 3.099 ± 0.095
4.793LysLeu: 4.793 ± 0.092
1.588LysMet: 1.588 ± 0.06
2.528LysAsn: 2.528 ± 0.084
1.777LysPro: 1.777 ± 0.071
2.658LysGln: 2.658 ± 0.073
2.695LysArg: 2.695 ± 0.096
3.03LysSer: 3.03 ± 0.079
2.904LysThr: 2.904 ± 0.074
3.794LysVal: 3.794 ± 0.121
0.439LysTrp: 0.439 ± 0.028
2.169LysTyr: 2.169 ± 0.075
0.0LysXaa: 0.0 ± 0.0
Leu
7.289LeuAla: 7.289 ± 0.145
0.656LeuCys: 0.656 ± 0.035
5.621LeuAsp: 5.621 ± 0.098
7.035LeuGlu: 7.035 ± 0.118
3.905LeuPhe: 3.905 ± 0.11
6.028LeuGly: 6.028 ± 0.132
1.82LeuHis: 1.82 ± 0.064
8.148LeuIle: 8.148 ± 0.159
5.875LeuLys: 5.875 ± 0.124
9.372LeuLeu: 9.372 ± 0.18
2.738LeuMet: 2.738 ± 0.076
5.079LeuAsn: 5.079 ± 0.111
3.875LeuPro: 3.875 ± 0.093
3.381LeuGln: 3.381 ± 0.099
3.81LeuArg: 3.81 ± 0.097
7.112LeuSer: 7.112 ± 0.129
5.93LeuThr: 5.93 ± 0.098
5.973LeuVal: 5.973 ± 0.128
0.768LeuTrp: 0.768 ± 0.048
3.438LeuTyr: 3.438 ± 0.086
0.0LeuXaa: 0.0 ± 0.0
Met
1.942MetAla: 1.942 ± 0.065
0.138MetCys: 0.138 ± 0.016
1.596MetAsp: 1.596 ± 0.057
1.757MetGlu: 1.757 ± 0.065
0.794MetPhe: 0.794 ± 0.051
1.68MetGly: 1.68 ± 0.062
0.5MetHis: 0.5 ± 0.032
2.307MetIle: 2.307 ± 0.069
1.795MetLys: 1.795 ± 0.067
2.386MetLeu: 2.386 ± 0.075
0.881MetMet: 0.881 ± 0.046
1.631MetAsn: 1.631 ± 0.06
0.916MetPro: 0.916 ± 0.046
1.034MetGln: 1.034 ± 0.047
1.19MetArg: 1.19 ± 0.049
1.712MetSer: 1.712 ± 0.059
1.773MetThr: 1.773 ± 0.06
1.805MetVal: 1.805 ± 0.056
0.102MetTrp: 0.102 ± 0.014
0.719MetTyr: 0.719 ± 0.038
0.0MetXaa: 0.0 ± 0.0
Asn
2.703AsnAla: 2.703 ± 0.075
0.286AsnCys: 0.286 ± 0.022
2.336AsnAsp: 2.336 ± 0.073
3.434AsnGlu: 3.434 ± 0.085
1.903AsnPhe: 1.903 ± 0.059
2.73AsnGly: 2.73 ± 0.08
1.355AsnHis: 1.355 ± 0.045
3.532AsnIle: 3.532 ± 0.094
2.429AsnLys: 2.429 ± 0.079
4.224AsnLeu: 4.224 ± 0.096
1.131AsnMet: 1.131 ± 0.047
2.092AsnAsn: 2.092 ± 0.077
2.518AsnPro: 2.518 ± 0.065
3.168AsnGln: 3.168 ± 0.094
2.171AsnArg: 2.171 ± 0.081
2.232AsnSer: 2.232 ± 0.08
2.134AsnThr: 2.134 ± 0.072
2.638AsnVal: 2.638 ± 0.08
0.429AsnTrp: 0.429 ± 0.033
2.112AsnTyr: 2.112 ± 0.066
0.0AsnXaa: 0.0 ± 0.0
Pro
2.405ProAla: 2.405 ± 0.086
0.171ProCys: 0.171 ± 0.019
2.122ProAsp: 2.122 ± 0.087
3.394ProGlu: 3.394 ± 0.093
1.606ProPhe: 1.606 ± 0.062
2.299ProGly: 2.299 ± 0.075
0.869ProHis: 0.869 ± 0.042
3.0ProIle: 3.0 ± 0.08
1.832ProLys: 1.832 ± 0.065
3.146ProLeu: 3.146 ± 0.085
0.999ProMet: 0.999 ± 0.039
1.903ProAsn: 1.903 ± 0.069
0.892ProPro: 0.892 ± 0.043
1.45ProGln: 1.45 ± 0.059
1.237ProArg: 1.237 ± 0.047
2.376ProSer: 2.376 ± 0.059
2.321ProThr: 2.321 ± 0.067
2.768ProVal: 2.768 ± 0.086
0.309ProTrp: 0.309 ± 0.024
1.592ProTyr: 1.592 ± 0.058
0.0ProXaa: 0.0 ± 0.0
Gln
4.1GlnAla: 4.1 ± 0.115
0.238GlnCys: 0.238 ± 0.022
2.155GlnAsp: 2.155 ± 0.07
3.321GlnGlu: 3.321 ± 0.095
1.907GlnPhe: 1.907 ± 0.07
2.715GlnGly: 2.715 ± 0.078
1.131GlnHis: 1.131 ± 0.046
3.763GlnIle: 3.763 ± 0.107
2.096GlnLys: 2.096 ± 0.073
5.883GlnLeu: 5.883 ± 0.147
1.342GlnMet: 1.342 ± 0.053
1.891GlnAsn: 1.891 ± 0.06
1.905GlnPro: 1.905 ± 0.062
2.904GlnGln: 2.904 ± 0.112
2.545GlnArg: 2.545 ± 0.073
3.302GlnSer: 3.302 ± 0.113
2.593GlnThr: 2.593 ± 0.079
3.609GlnVal: 3.609 ± 0.091
0.625GlnTrp: 0.625 ± 0.032
1.883GlnTyr: 1.883 ± 0.062
0.0GlnXaa: 0.0 ± 0.0
Arg
2.539ArgAla: 2.539 ± 0.081
0.292ArgCys: 0.292 ± 0.027
2.336ArgAsp: 2.336 ± 0.081
3.353ArgGlu: 3.353 ± 0.083
1.803ArgPhe: 1.803 ± 0.06
2.466ArgGly: 2.466 ± 0.066
1.04ArgHis: 1.04 ± 0.044
3.597ArgIle: 3.597 ± 0.093
2.553ArgLys: 2.553 ± 0.064
4.624ArgLeu: 4.624 ± 0.105
1.265ArgMet: 1.265 ± 0.052
1.962ArgAsn: 1.962 ± 0.072
1.535ArgPro: 1.535 ± 0.063
2.565ArgGln: 2.565 ± 0.078
2.461ArgArg: 2.461 ± 0.072
2.427ArgSer: 2.427 ± 0.066
2.134ArgThr: 2.134 ± 0.065
2.959ArgVal: 2.959 ± 0.077
0.506ArgTrp: 0.506 ± 0.04
2.09ArgTyr: 2.09 ± 0.074
0.0ArgXaa: 0.0 ± 0.0
Ser
3.607SerAla: 3.607 ± 0.096
0.323SerCys: 0.323 ± 0.027
3.284SerAsp: 3.284 ± 0.092
4.504SerGlu: 4.504 ± 0.102
2.595SerPhe: 2.595 ± 0.078
4.145SerGly: 4.145 ± 0.105
1.336SerHis: 1.336 ± 0.05
5.022SerIle: 5.022 ± 0.107
3.331SerLys: 3.331 ± 0.1
5.849SerLeu: 5.849 ± 0.125
1.7SerMet: 1.7 ± 0.062
2.801SerAsn: 2.801 ± 0.075
2.094SerPro: 2.094 ± 0.077
3.01SerGln: 3.01 ± 0.09
2.551SerArg: 2.551 ± 0.073
3.727SerSer: 3.727 ± 0.109
3.251SerThr: 3.251 ± 0.078
3.771SerVal: 3.771 ± 0.08
0.532SerTrp: 0.532 ± 0.037
2.348SerTyr: 2.348 ± 0.071
0.0SerXaa: 0.0 ± 0.0
Thr
3.625ThrAla: 3.625 ± 0.083
0.292ThrCys: 0.292 ± 0.025
3.01ThrAsp: 3.01 ± 0.075
3.731ThrGlu: 3.731 ± 0.121
2.248ThrPhe: 2.248 ± 0.059
3.836ThrGly: 3.836 ± 0.101
1.33ThrHis: 1.33 ± 0.05
4.596ThrIle: 4.596 ± 0.104
2.579ThrLys: 2.579 ± 0.084
5.847ThrLeu: 5.847 ± 0.11
1.263ThrMet: 1.263 ± 0.048
2.336ThrAsn: 2.336 ± 0.071
2.492ThrPro: 2.492 ± 0.099
2.589ThrGln: 2.589 ± 0.066
2.183ThrArg: 2.183 ± 0.07
3.241ThrSer: 3.241 ± 0.081
3.457ThrThr: 3.457 ± 0.149
3.891ThrVal: 3.891 ± 0.101
0.429ThrTrp: 0.429 ± 0.028
2.228ThrTyr: 2.228 ± 0.068
0.0ThrXaa: 0.0 ± 0.0
Val
4.84ValAla: 4.84 ± 0.106
0.386ValCys: 0.386 ± 0.03
4.133ValAsp: 4.133 ± 0.084
5.27ValGlu: 5.27 ± 0.13
2.494ValPhe: 2.494 ± 0.085
4.468ValGly: 4.468 ± 0.113
1.271ValHis: 1.271 ± 0.045
5.711ValIle: 5.711 ± 0.1
3.65ValLys: 3.65 ± 0.094
5.902ValLeu: 5.902 ± 0.129
1.899ValMet: 1.899 ± 0.069
3.227ValAsn: 3.227 ± 0.083
2.522ValPro: 2.522 ± 0.076
2.681ValGln: 2.681 ± 0.081
2.693ValArg: 2.693 ± 0.08
3.97ValSer: 3.97 ± 0.101
4.175ValThr: 4.175 ± 0.105
4.754ValVal: 4.754 ± 0.114
0.504ValTrp: 0.504 ± 0.027
2.498ValTyr: 2.498 ± 0.073
0.0ValXaa: 0.0 ± 0.0
Trp
0.485TrpAla: 0.485 ± 0.033
0.055TrpCys: 0.055 ± 0.011
0.471TrpAsp: 0.471 ± 0.03
0.605TrpGlu: 0.605 ± 0.04
0.424TrpPhe: 0.424 ± 0.037
0.522TrpGly: 0.522 ± 0.031
0.227TrpHis: 0.227 ± 0.023
0.741TrpIle: 0.741 ± 0.036
0.349TrpLys: 0.349 ± 0.029
1.125TrpLeu: 1.125 ± 0.053
0.292TrpMet: 0.292 ± 0.029
0.426TrpAsn: 0.426 ± 0.032
0.246TrpPro: 0.246 ± 0.025
0.623TrpGln: 0.623 ± 0.038
0.355TrpArg: 0.355 ± 0.025
0.451TrpSer: 0.451 ± 0.031
0.374TrpThr: 0.374 ± 0.028
0.611TrpVal: 0.611 ± 0.043
0.091TrpTrp: 0.091 ± 0.014
0.323TrpTyr: 0.323 ± 0.028
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.437TyrAla: 2.437 ± 0.07
0.349TyrCys: 0.349 ± 0.026
2.533TyrAsp: 2.533 ± 0.077
2.658TyrGlu: 2.658 ± 0.066
1.903TyrPhe: 1.903 ± 0.072
2.49TyrGly: 2.49 ± 0.076
1.208TyrHis: 1.208 ± 0.044
2.766TyrIle: 2.766 ± 0.073
1.509TyrLys: 1.509 ± 0.062
4.555TyrLeu: 4.555 ± 0.121
0.786TyrMet: 0.786 ± 0.038
1.856TyrAsn: 1.856 ± 0.064
1.751TyrPro: 1.751 ± 0.049
3.03TyrGln: 3.03 ± 0.096
2.299TyrArg: 2.299 ± 0.073
2.327TyrSer: 2.327 ± 0.074
1.956TyrThr: 1.956 ± 0.066
2.309TyrVal: 2.309 ± 0.067
0.341TyrTrp: 0.341 ± 0.028
2.074TyrTyr: 2.074 ± 0.08
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1621 proteins (507603 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski