Amino acid dipepetide frequency for bacteria symbiont BFo1 of Frankliniella occidentalis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	12.143AlaAla: 12.143 ± 0.137	1.071AlaCys: 1.071 ± 0.032	5.338AlaAsp: 5.338 ± 0.073	6.115AlaGlu: 6.115 ± 0.077	3.527AlaPhe: 3.527 ± 0.049	8.288AlaGly: 8.288 ± 0.094	1.832AlaHis: 1.832 ± 0.038	5.785AlaIle: 5.785 ± 0.078	3.647AlaLys: 3.647 ± 0.063	12.824AlaLeu: 12.824 ± 0.125	3.011AlaMet: 3.011 ± 0.049	3.014AlaAsn: 3.014 ± 0.047	3.829AlaPro: 3.829 ± 0.07	5.049AlaGln: 5.049 ± 0.076	5.941AlaArg: 5.941 ± 0.065	6.166AlaSer: 6.166 ± 0.068	4.848AlaThr: 4.848 ± 0.066	7.159AlaVal: 7.159 ± 0.07	1.633AlaTrp: 1.633 ± 0.034	1.992AlaTyr: 1.992 ± 0.036	0.0AlaXaa: 0.0 ± 0.0
Cys	0.949CysAla: 0.949 ± 0.026	0.181CysCys: 0.181 ± 0.011	0.557CysAsp: 0.557 ± 0.022	0.541CysGlu: 0.541 ± 0.022	0.413CysPhe: 0.413 ± 0.017	1.056CysGly: 1.056 ± 0.027	0.295CysHis: 0.295 ± 0.015	0.511CysIle: 0.511 ± 0.02	0.281CysLys: 0.281 ± 0.016	1.005CysLeu: 1.005 ± 0.029	0.216CysMet: 0.216 ± 0.013	0.292CysAsn: 0.292 ± 0.016	0.457CysPro: 0.457 ± 0.017	0.493CysGln: 0.493 ± 0.019	0.633CysArg: 0.633 ± 0.02	0.667CysSer: 0.667 ± 0.023	0.453CysThr: 0.453 ± 0.017	0.682CysVal: 0.682 ± 0.021	0.181CysTrp: 0.181 ± 0.012	0.316CysTyr: 0.316 ± 0.016	0.0CysXaa: 0.0 ± 0.0
Asp	5.433AspAla: 5.433 ± 0.067	0.467AspCys: 0.467 ± 0.019	2.914AspAsp: 2.914 ± 0.06	3.38AspGlu: 3.38 ± 0.057	2.165AspPhe: 2.165 ± 0.035	3.99AspGly: 3.99 ± 0.067	0.965AspHis: 0.965 ± 0.027	3.217AspIle: 3.217 ± 0.048	2.299AspLys: 2.299 ± 0.04	4.704AspLeu: 4.704 ± 0.057	1.258AspMet: 1.258 ± 0.031	2.14AspAsn: 2.14 ± 0.045	2.222AspPro: 2.222 ± 0.042	1.659AspGln: 1.659 ± 0.034	3.042AspArg: 3.042 ± 0.056	3.088AspSer: 3.088 ± 0.052	2.379AspThr: 2.379 ± 0.046	3.602AspVal: 3.602 ± 0.048	0.821AspTrp: 0.821 ± 0.027	1.841AspTyr: 1.841 ± 0.039	0.0AspXaa: 0.0 ± 0.0
Glu	5.275GluAla: 5.275 ± 0.074	0.435GluCys: 0.435 ± 0.019	2.232GluAsp: 2.232 ± 0.045	3.121GluGlu: 3.121 ± 0.063	1.848GluPhe: 1.848 ± 0.04	3.449GluGly: 3.449 ± 0.055	1.272GluHis: 1.272 ± 0.032	3.171GluIle: 3.171 ± 0.054	2.973GluLys: 2.973 ± 0.047	5.902GluLeu: 5.902 ± 0.08	1.728GluMet: 1.728 ± 0.038	2.07GluAsn: 2.07 ± 0.042	1.981GluPro: 1.981 ± 0.039	3.485GluGln: 3.485 ± 0.057	3.589GluArg: 3.589 ± 0.056	2.989GluSer: 2.989 ± 0.044	2.645GluThr: 2.645 ± 0.046	3.816GluVal: 3.816 ± 0.051	0.78GluTrp: 0.78 ± 0.022	1.349GluTyr: 1.349 ± 0.034	0.0GluXaa: 0.0 ± 0.0
Phe	3.713PheAla: 3.713 ± 0.058	0.543PheCys: 0.543 ± 0.019	2.339PheAsp: 2.339 ± 0.039	1.638PheGlu: 1.638 ± 0.037	1.558PhePhe: 1.558 ± 0.042	3.056PheGly: 3.056 ± 0.057	0.78PheHis: 0.78 ± 0.022	2.4PheIle: 2.4 ± 0.039	1.221PheLys: 1.221 ± 0.033	3.126PheLeu: 3.126 ± 0.064	0.944PheMet: 0.944 ± 0.026	1.722PheAsn: 1.722 ± 0.036	1.55PhePro: 1.55 ± 0.035	1.2PheGln: 1.2 ± 0.03	1.856PheArg: 1.856 ± 0.035	3.302PheSer: 3.302 ± 0.052	2.293PheThr: 2.293 ± 0.038	2.339PheVal: 2.339 ± 0.041	0.624PheTrp: 0.624 ± 0.023	1.146PheTyr: 1.146 ± 0.034	0.0PheXaa: 0.0 ± 0.0
Gly	6.621GlyAla: 6.621 ± 0.064	0.949GlyCys: 0.949 ± 0.027	3.706GlyAsp: 3.706 ± 0.063	4.601GlyGlu: 4.601 ± 0.057	3.253GlyPhe: 3.253 ± 0.05	5.683GlyGly: 5.683 ± 0.085	1.637GlyHis: 1.637 ± 0.036	4.854GlyIle: 4.854 ± 0.069	3.849GlyLys: 3.849 ± 0.064	7.518GlyLeu: 7.518 ± 0.08	2.326GlyMet: 2.326 ± 0.04	2.711GlyAsn: 2.711 ± 0.062	2.08GlyPro: 2.08 ± 0.039	3.191GlyGln: 3.191 ± 0.053	4.047GlyArg: 4.047 ± 0.063	4.815GlySer: 4.815 ± 0.075	3.732GlyThr: 3.732 ± 0.067	5.703GlyVal: 5.703 ± 0.068	1.349GlyTrp: 1.349 ± 0.034	2.588GlyTyr: 2.588 ± 0.053	0.0GlyXaa: 0.0 ± 0.0
His	1.986HisAla: 1.986 ± 0.039	0.327HisCys: 0.327 ± 0.016	1.154HisAsp: 1.154 ± 0.028	0.994HisGlu: 0.994 ± 0.026	1.002HisPhe: 1.002 ± 0.024	1.78HisGly: 1.78 ± 0.04	0.754HisHis: 0.754 ± 0.03	1.208HisIle: 1.208 ± 0.031	0.676HisLys: 0.676 ± 0.022	2.243HisLeu: 2.243 ± 0.04	0.512HisMet: 0.512 ± 0.019	0.814HisAsn: 0.814 ± 0.026	1.352HisPro: 1.352 ± 0.032	1.347HisGln: 1.347 ± 0.032	1.247HisArg: 1.247 ± 0.031	1.39HisSer: 1.39 ± 0.036	0.965HisThr: 0.965 ± 0.029	1.164HisVal: 1.164 ± 0.031	0.418HisTrp: 0.418 ± 0.017	0.846HisTyr: 0.846 ± 0.024	0.0HisXaa: 0.0 ± 0.0
Ile	6.469IleAla: 6.469 ± 0.076	0.629IleCys: 0.629 ± 0.022	3.422IleAsp: 3.422 ± 0.05	3.139IleGlu: 3.139 ± 0.046	1.922IlePhe: 1.922 ± 0.044	4.584IleGly: 4.584 ± 0.066	1.123IleHis: 1.123 ± 0.03	2.959IleIle: 2.959 ± 0.063	2.232IleLys: 2.232 ± 0.046	4.446IleLeu: 4.446 ± 0.077	1.134IleMet: 1.134 ± 0.027	2.47IleAsn: 2.47 ± 0.049	2.547IlePro: 2.547 ± 0.04	1.762IleGln: 1.762 ± 0.037	2.8IleArg: 2.8 ± 0.043	3.786IleSer: 3.786 ± 0.055	3.318IleThr: 3.318 ± 0.046	3.721IleVal: 3.721 ± 0.054	0.69IleTrp: 0.69 ± 0.022	1.435IleTyr: 1.435 ± 0.032	0.0IleXaa: 0.0 ± 0.0
Lys	4.054LysAla: 4.054 ± 0.066	0.228LysCys: 0.228 ± 0.013	1.88LysAsp: 1.88 ± 0.043	2.169LysGlu: 2.169 ± 0.041	1.06LysPhe: 1.06 ± 0.029	2.859LysGly: 2.859 ± 0.051	0.772LysHis: 0.772 ± 0.025	2.198LysIle: 2.198 ± 0.043	2.041LysLys: 2.041 ± 0.045	4.068LysLeu: 4.068 ± 0.057	1.216LysMet: 1.216 ± 0.03	1.6LysAsn: 1.6 ± 0.035	2.063LysPro: 2.063 ± 0.044	2.013LysGln: 2.013 ± 0.034	2.477LysArg: 2.477 ± 0.05	2.368LysSer: 2.368 ± 0.05	2.369LysThr: 2.369 ± 0.039	2.844LysVal: 2.844 ± 0.049	0.437LysTrp: 0.437 ± 0.019	1.001LysTyr: 1.001 ± 0.027	0.0LysXaa: 0.0 ± 0.0
Leu	12.264LeuAla: 12.264 ± 0.121	1.22LeuCys: 1.22 ± 0.027	5.484LeuAsp: 5.484 ± 0.071	5.278LeuGlu: 5.278 ± 0.072	4.151LeuPhe: 4.151 ± 0.06	7.279LeuGly: 7.279 ± 0.087	2.345LeuHis: 2.345 ± 0.041	5.673LeuIle: 5.673 ± 0.078	4.552LeuLys: 4.552 ± 0.06	12.733LeuLeu: 12.733 ± 0.146	3.109LeuMet: 3.109 ± 0.047	4.182LeuAsn: 4.182 ± 0.058	5.897LeuPro: 5.897 ± 0.079	4.67LeuGln: 4.67 ± 0.059	6.314LeuArg: 6.314 ± 0.076	7.994LeuSer: 7.994 ± 0.084	6.338LeuThr: 6.338 ± 0.072	7.052LeuVal: 7.052 ± 0.076	1.459LeuTrp: 1.459 ± 0.039	2.518LeuTyr: 2.518 ± 0.043	0.001LeuXaa: 0.001 ± 0.001
Met	2.963MetAla: 2.963 ± 0.048	0.173MetCys: 0.173 ± 0.011	1.155MetAsp: 1.155 ± 0.027	1.199MetGlu: 1.199 ± 0.032	0.814MetPhe: 0.814 ± 0.023	1.762MetGly: 1.762 ± 0.036	0.514MetHis: 0.514 ± 0.019	1.426MetIle: 1.426 ± 0.033	1.425MetLys: 1.425 ± 0.031	3.169MetLeu: 3.169 ± 0.054	0.882MetMet: 0.882 ± 0.022	1.085MetAsn: 1.085 ± 0.031	1.335MetPro: 1.335 ± 0.029	1.256MetGln: 1.256 ± 0.032	1.519MetArg: 1.519 ± 0.033	1.94MetSer: 1.94 ± 0.039	1.709MetThr: 1.709 ± 0.031	1.918MetVal: 1.918 ± 0.04	0.238MetTrp: 0.238 ± 0.014	0.464MetTyr: 0.464 ± 0.018	0.0MetXaa: 0.0 ± 0.0
Asn	3.531AsnAla: 3.531 ± 0.063	0.317AsnCys: 0.317 ± 0.014	1.907AsnAsp: 1.907 ± 0.038	1.696AsnGlu: 1.696 ± 0.034	1.268AsnPhe: 1.268 ± 0.032	3.092AsnGly: 3.092 ± 0.062	0.8AsnHis: 0.8 ± 0.024	2.106AsnIle: 2.106 ± 0.047	1.402AsnLys: 1.402 ± 0.036	3.522AsnLeu: 3.522 ± 0.054	0.832AsnMet: 0.832 ± 0.024	1.493AsnAsn: 1.493 ± 0.038	2.073AsnPro: 2.073 ± 0.038	1.624AsnGln: 1.624 ± 0.034	2.001AsnArg: 2.001 ± 0.035	2.191AsnSer: 2.191 ± 0.045	1.832AsnThr: 1.832 ± 0.046	2.41AsnVal: 2.41 ± 0.045	0.561AsnTrp: 0.561 ± 0.02	1.103AsnTyr: 1.103 ± 0.03	0.0AsnXaa: 0.0 ± 0.0
Pro	5.04ProAla: 5.04 ± 0.071	0.367ProCys: 0.367 ± 0.014	2.812ProAsp: 2.812 ± 0.046	3.223ProGlu: 3.223 ± 0.046	1.752ProPhe: 1.752 ± 0.034	3.598ProGly: 3.598 ± 0.056	1.044ProHis: 1.044 ± 0.027	1.774ProIle: 1.774 ± 0.034	1.448ProLys: 1.448 ± 0.031	5.444ProLeu: 5.444 ± 0.079	1.098ProMet: 1.098 ± 0.027	1.207ProAsn: 1.207 ± 0.033	1.836ProPro: 1.836 ± 0.045	2.586ProGln: 2.586 ± 0.045	1.928ProArg: 1.928 ± 0.035	2.18ProSer: 2.18 ± 0.041	2.078ProThr: 2.078 ± 0.041	3.806ProVal: 3.806 ± 0.057	0.734ProTrp: 0.734 ± 0.022	1.161ProTyr: 1.161 ± 0.031	0.001ProXaa: 0.001 ± 0.001
Gln	5.117GlnAla: 5.117 ± 0.076	0.38GlnCys: 0.38 ± 0.016	1.94GlnAsp: 1.94 ± 0.045	2.132GlnGlu: 2.132 ± 0.043	1.533GlnPhe: 1.533 ± 0.035	3.239GlnGly: 3.239 ± 0.049	1.491GlnHis: 1.491 ± 0.036	2.269GlnIle: 2.269 ± 0.04	1.702GlnLys: 1.702 ± 0.034	5.809GlnLeu: 5.809 ± 0.073	1.308GlnMet: 1.308 ± 0.027	1.396GlnAsn: 1.396 ± 0.031	2.632GlnPro: 2.632 ± 0.056	4.485GlnGln: 4.485 ± 0.094	3.747GlnArg: 3.747 ± 0.059	2.535GlnSer: 2.535 ± 0.046	2.108GlnThr: 2.108 ± 0.038	3.184GlnVal: 3.184 ± 0.055	0.721GlnTrp: 0.721 ± 0.022	1.171GlnTyr: 1.171 ± 0.029	0.0GlnXaa: 0.0 ± 0.0
Arg	5.107ArgAla: 5.107 ± 0.065	0.603ArgCys: 0.603 ± 0.021	3.123ArgAsp: 3.123 ± 0.045	3.64ArgGlu: 3.64 ± 0.058	2.579ArgPhe: 2.579 ± 0.041	3.534ArgGly: 3.534 ± 0.047	1.584ArgHis: 1.584 ± 0.036	3.24ArgIle: 3.24 ± 0.049	2.27ArgLys: 2.27 ± 0.045	6.661ArgLeu: 6.661 ± 0.086	1.554ArgMet: 1.554 ± 0.033	1.985ArgAsn: 1.985 ± 0.038	2.349ArgPro: 2.349 ± 0.04	3.365ArgGln: 3.365 ± 0.055	3.571ArgArg: 3.571 ± 0.054	3.101ArgSer: 3.101 ± 0.047	2.571ArgThr: 2.571 ± 0.041	3.996ArgVal: 3.996 ± 0.053	1.042ArgTrp: 1.042 ± 0.027	2.167ArgTyr: 2.167 ± 0.04	0.0ArgXaa: 0.0 ± 0.0
Ser	6.655SerAla: 6.655 ± 0.076	0.602SerCys: 0.602 ± 0.021	3.394SerAsp: 3.394 ± 0.055	3.367SerGlu: 3.367 ± 0.054	2.383SerPhe: 2.383 ± 0.048	6.047SerGly: 6.047 ± 0.078	1.455SerHis: 1.455 ± 0.026	2.892SerIle: 2.892 ± 0.046	2.053SerLys: 2.053 ± 0.038	7.09SerLeu: 7.09 ± 0.086	1.577SerMet: 1.577 ± 0.031	1.961SerAsn: 1.961 ± 0.044	2.728SerPro: 2.728 ± 0.047	2.824SerGln: 2.824 ± 0.051	3.582SerArg: 3.582 ± 0.057	3.999SerSer: 3.999 ± 0.076	3.101SerThr: 3.101 ± 0.058	4.464SerVal: 4.464 ± 0.067	1.191SerTrp: 1.191 ± 0.032	1.731SerTyr: 1.731 ± 0.036	0.0SerXaa: 0.0 ± 0.0
Thr	5.079ThrAla: 5.079 ± 0.074	0.446ThrCys: 0.446 ± 0.018	2.502ThrAsp: 2.502 ± 0.048	2.397ThrGlu: 2.397 ± 0.042	1.94ThrPhe: 1.94 ± 0.041	4.173ThrGly: 4.173 ± 0.059	1.137ThrHis: 1.137 ± 0.032	2.722ThrIle: 2.722 ± 0.047	1.402ThrLys: 1.402 ± 0.035	7.58ThrLeu: 7.58 ± 0.07	1.033ThrMet: 1.033 ± 0.027	1.437ThrAsn: 1.437 ± 0.038	3.186ThrPro: 3.186 ± 0.059	2.175ThrGln: 2.175 ± 0.038	3.084ThrArg: 3.084 ± 0.047	2.989ThrSer: 2.989 ± 0.055	2.811ThrThr: 2.811 ± 0.061	3.811ThrVal: 3.811 ± 0.062	0.729ThrTrp: 0.729 ± 0.025	1.092ThrTyr: 1.092 ± 0.03	0.001ThrXaa: 0.001 ± 0.001
Val	7.354ValAla: 7.354 ± 0.078	0.696ValCys: 0.696 ± 0.024	3.629ValAsp: 3.629 ± 0.053	3.838ValGlu: 3.838 ± 0.056	2.432ValPhe: 2.432 ± 0.05	4.706ValGly: 4.706 ± 0.067	1.178ValHis: 1.178 ± 0.027	4.234ValIle: 4.234 ± 0.054	2.95ValLys: 2.95 ± 0.043	7.245ValLeu: 7.245 ± 0.077	2.203ValMet: 2.203 ± 0.044	2.743ValAsn: 2.743 ± 0.041	2.984ValPro: 2.984 ± 0.042	2.606ValGln: 2.606 ± 0.044	3.669ValArg: 3.669 ± 0.049	4.937ValSer: 4.937 ± 0.06	4.27ValThr: 4.27 ± 0.064	5.538ValVal: 5.538 ± 0.077	0.913ValTrp: 0.913 ± 0.022	1.622ValTyr: 1.622 ± 0.034	0.0ValXaa: 0.0 ± 0.0
Trp	1.067TrpAla: 1.067 ± 0.029	0.18TrpCys: 0.18 ± 0.011	0.629TrpAsp: 0.629 ± 0.022	0.538TrpGlu: 0.538 ± 0.019	0.667TrpPhe: 0.667 ± 0.026	0.947TrpGly: 0.947 ± 0.027	0.443TrpHis: 0.443 ± 0.016	0.705TrpIle: 0.705 ± 0.024	0.503TrpLys: 0.503 ± 0.02	2.355TrpLeu: 2.355 ± 0.049	0.425TrpMet: 0.425 ± 0.017	0.509TrpAsn: 0.509 ± 0.019	0.678TrpPro: 0.678 ± 0.021	1.342TrpGln: 1.342 ± 0.04	1.092TrpArg: 1.092 ± 0.025	0.898TrpSer: 0.898 ± 0.028	0.584TrpThr: 0.584 ± 0.023	0.915TrpVal: 0.915 ± 0.023	0.238TrpTrp: 0.238 ± 0.014	0.454TrpTyr: 0.454 ± 0.018	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.392TyrAla: 2.392 ± 0.039	0.364TyrCys: 0.364 ± 0.015	1.472TyrAsp: 1.472 ± 0.037	1.104TyrGlu: 1.104 ± 0.027	1.085TyrPhe: 1.085 ± 0.027	2.091TyrGly: 2.091 ± 0.039	0.757TyrHis: 0.757 ± 0.023	1.244TyrIle: 1.244 ± 0.033	0.792TyrLys: 0.792 ± 0.024	3.07TyrLeu: 3.07 ± 0.054	0.575TyrMet: 0.575 ± 0.02	0.93TyrAsn: 0.93 ± 0.026	1.34TyrPro: 1.34 ± 0.029	1.769TyrGln: 1.769 ± 0.043	1.903TyrArg: 1.903 ± 0.039	1.758TyrSer: 1.758 ± 0.034	1.318TyrThr: 1.318 ± 0.033	1.624TyrVal: 1.624 ± 0.037	0.41TyrTrp: 0.41 ± 0.015	0.85TyrTyr: 0.85 ± 0.027	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.001XaaLys: 0.001 ± 0.001	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.001XaaArg: 0.001 ± 0.001	0.0XaaSer: 0.0 ± 0.0	0.001XaaThr: 0.001 ± 0.001	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4649 proteins (1442933 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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