Amino acid dipepetide frequency for Pontibacillus chungwhensis BH030062

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	4.821AlaAla: 4.821 ± 0.093	0.554AlaCys: 0.554 ± 0.025	3.145AlaAsp: 3.145 ± 0.063	4.37AlaGlu: 4.37 ± 0.077	3.363AlaPhe: 3.363 ± 0.06	5.035AlaGly: 5.035 ± 0.083	1.378AlaHis: 1.378 ± 0.041	5.442AlaIle: 5.442 ± 0.073	4.186AlaLys: 4.186 ± 0.076	7.153AlaLeu: 7.153 ± 0.101	2.114AlaMet: 2.114 ± 0.052	2.546AlaAsn: 2.546 ± 0.05	2.189AlaPro: 2.189 ± 0.043	2.398AlaGln: 2.398 ± 0.051	2.605AlaArg: 2.605 ± 0.058	4.405AlaSer: 4.405 ± 0.069	3.519AlaThr: 3.519 ± 0.066	5.04AlaVal: 5.04 ± 0.071	0.66AlaTrp: 0.66 ± 0.026	2.442AlaTyr: 2.442 ± 0.052	0.0AlaXaa: 0.0 ± 0.0
Cys	0.373CysAla: 0.373 ± 0.02	0.078CysCys: 0.078 ± 0.009	0.375CysAsp: 0.375 ± 0.021	0.415CysGlu: 0.415 ± 0.019	0.269CysPhe: 0.269 ± 0.018	0.559CysGly: 0.559 ± 0.025	0.184CysHis: 0.184 ± 0.013	0.366CysIle: 0.366 ± 0.021	0.322CysLys: 0.322 ± 0.017	0.576CysLeu: 0.576 ± 0.024	0.164CysMet: 0.164 ± 0.013	0.24CysAsn: 0.24 ± 0.013	0.301CysPro: 0.301 ± 0.017	0.219CysGln: 0.219 ± 0.013	0.233CysArg: 0.233 ± 0.017	0.437CysSer: 0.437 ± 0.023	0.338CysThr: 0.338 ± 0.018	0.407CysVal: 0.407 ± 0.019	0.05CysTrp: 0.05 ± 0.007	0.255CysTyr: 0.255 ± 0.016	0.0CysXaa: 0.0 ± 0.0
Asp	3.335AspAla: 3.335 ± 0.062	0.323AspCys: 0.323 ± 0.022	2.617AspAsp: 2.617 ± 0.055	5.039AspGlu: 5.039 ± 0.076	2.312AspPhe: 2.312 ± 0.052	3.539AspGly: 3.539 ± 0.062	1.562AspHis: 1.562 ± 0.036	3.687AspIle: 3.687 ± 0.06	2.933AspLys: 2.933 ± 0.052	5.507AspLeu: 5.507 ± 0.083	1.433AspMet: 1.433 ± 0.043	1.635AspAsn: 1.635 ± 0.041	2.317AspPro: 2.317 ± 0.051	2.918AspGln: 2.918 ± 0.069	2.539AspArg: 2.539 ± 0.046	2.673AspSer: 2.673 ± 0.05	2.67AspThr: 2.67 ± 0.05	4.174AspVal: 4.174 ± 0.069	0.671AspTrp: 0.671 ± 0.024	2.372AspTyr: 2.372 ± 0.053	0.0AspXaa: 0.0 ± 0.0
Glu	6.058GluAla: 6.058 ± 0.095	0.35GluCys: 0.35 ± 0.019	4.938GluAsp: 4.938 ± 0.078	8.593GluGlu: 8.593 ± 0.134	2.358GluPhe: 2.358 ± 0.051	5.311GluGly: 5.311 ± 0.083	1.77GluHis: 1.77 ± 0.041	4.823GluIle: 4.823 ± 0.081	5.8GluLys: 5.8 ± 0.088	6.674GluLeu: 6.674 ± 0.095	2.443GluMet: 2.443 ± 0.049	3.353GluAsn: 3.353 ± 0.068	2.204GluPro: 2.204 ± 0.051	3.93GluGln: 3.93 ± 0.101	3.961GluArg: 3.961 ± 0.074	4.06GluSer: 4.06 ± 0.073	4.203GluThr: 4.203 ± 0.075	5.695GluVal: 5.695 ± 0.094	1.02GluTrp: 1.02 ± 0.031	2.362GluTyr: 2.362 ± 0.052	0.0GluXaa: 0.0 ± 0.0
Phe	2.947PheAla: 2.947 ± 0.057	0.289PheCys: 0.289 ± 0.018	2.373PheAsp: 2.373 ± 0.05	2.929PheGlu: 2.929 ± 0.055	2.232PhePhe: 2.232 ± 0.065	3.354PheGly: 3.354 ± 0.066	1.034PheHis: 1.034 ± 0.03	3.545PheIle: 3.545 ± 0.073	2.317PheLys: 2.317 ± 0.052	4.559PheLeu: 4.559 ± 0.088	1.242PheMet: 1.242 ± 0.036	1.724PheAsn: 1.724 ± 0.041	1.687PhePro: 1.687 ± 0.036	1.713PheGln: 1.713 ± 0.035	1.531PheArg: 1.531 ± 0.037	3.163PheSer: 3.163 ± 0.066	2.657PheThr: 2.657 ± 0.042	3.151PheVal: 3.151 ± 0.061	0.469PheTrp: 0.469 ± 0.023	1.684PheTyr: 1.684 ± 0.047	0.0PheXaa: 0.0 ± 0.0
Gly	4.912GlyAla: 4.912 ± 0.084	0.562GlyCys: 0.562 ± 0.022	3.727GlyAsp: 3.727 ± 0.066	5.263GlyGlu: 5.263 ± 0.076	3.397GlyPhe: 3.397 ± 0.068	5.106GlyGly: 5.106 ± 0.088	1.395GlyHis: 1.395 ± 0.039	5.516GlyIle: 5.516 ± 0.075	4.456GlyLys: 4.456 ± 0.072	6.615GlyLeu: 6.615 ± 0.088	2.24GlyMet: 2.24 ± 0.048	2.618GlyAsn: 2.618 ± 0.056	1.799GlyPro: 1.799 ± 0.04	2.363GlyGln: 2.363 ± 0.054	2.681GlyArg: 2.681 ± 0.055	4.352GlySer: 4.352 ± 0.065	4.069GlyThr: 4.069 ± 0.071	5.604GlyVal: 5.604 ± 0.074	0.852GlyTrp: 0.852 ± 0.027	2.881GlyTyr: 2.881 ± 0.058	0.0GlyXaa: 0.0 ± 0.0
His	1.383HisAla: 1.383 ± 0.04	0.192HisCys: 0.192 ± 0.014	1.187HisAsp: 1.187 ± 0.035	1.565HisGlu: 1.565 ± 0.038	1.056HisPhe: 1.056 ± 0.035	1.352HisGly: 1.352 ± 0.039	0.752HisHis: 0.752 ± 0.028	1.595HisIle: 1.595 ± 0.043	1.25HisLys: 1.25 ± 0.029	2.271HisLeu: 2.271 ± 0.053	0.601HisMet: 0.601 ± 0.024	0.91HisAsn: 0.91 ± 0.027	1.199HisPro: 1.199 ± 0.034	0.949HisGln: 0.949 ± 0.032	0.891HisArg: 0.891 ± 0.028	1.342HisSer: 1.342 ± 0.035	1.215HisThr: 1.215 ± 0.031	1.616HisVal: 1.616 ± 0.044	0.245HisTrp: 0.245 ± 0.014	0.983HisTyr: 0.983 ± 0.034	0.0HisXaa: 0.0 ± 0.0
Ile	5.358IleAla: 5.358 ± 0.086	0.467IleCys: 0.467 ± 0.024	3.947IleAsp: 3.947 ± 0.071	5.488IleGlu: 5.488 ± 0.075	2.861IlePhe: 2.861 ± 0.063	5.721IleGly: 5.721 ± 0.082	1.733IleHis: 1.733 ± 0.043	4.907IleIle: 4.907 ± 0.078	3.516IleLys: 3.516 ± 0.054	6.462IleLeu: 6.462 ± 0.095	1.708IleMet: 1.708 ± 0.041	2.707IleAsn: 2.707 ± 0.048	3.167IlePro: 3.167 ± 0.054	3.047IleGln: 3.047 ± 0.047	2.92IleArg: 2.92 ± 0.046	4.439IleSer: 4.439 ± 0.066	4.108IleThr: 4.108 ± 0.07	5.177IleVal: 5.177 ± 0.077	0.628IleTrp: 0.628 ± 0.026	2.265IleTyr: 2.265 ± 0.051	0.0IleXaa: 0.0 ± 0.0
Lys	4.267LysAla: 4.267 ± 0.062	0.249LysCys: 0.249 ± 0.017	3.909LysAsp: 3.909 ± 0.065	6.762LysGlu: 6.762 ± 0.102	1.539LysPhe: 1.539 ± 0.04	4.647LysGly: 4.647 ± 0.063	1.359LysHis: 1.359 ± 0.037	3.397LysIle: 3.397 ± 0.058	4.94LysLys: 4.94 ± 0.084	4.796LysLeu: 4.796 ± 0.063	1.855LysMet: 1.855 ± 0.036	2.515LysAsn: 2.515 ± 0.048	2.118LysPro: 2.118 ± 0.05	3.245LysGln: 3.245 ± 0.067	3.512LysArg: 3.512 ± 0.066	3.424LysSer: 3.424 ± 0.059	3.174LysThr: 3.174 ± 0.06	4.295LysVal: 4.295 ± 0.066	0.898LysTrp: 0.898 ± 0.031	1.745LysTyr: 1.745 ± 0.044	0.0LysXaa: 0.0 ± 0.0
Leu	6.928LeuAla: 6.928 ± 0.092	0.569LeuCys: 0.569 ± 0.027	4.909LeuAsp: 4.909 ± 0.081	6.68LeuGlu: 6.68 ± 0.099	4.822LeuPhe: 4.822 ± 0.1	6.473LeuGly: 6.473 ± 0.083	2.156LeuHis: 2.156 ± 0.053	6.505LeuIle: 6.505 ± 0.103	5.776LeuLys: 5.776 ± 0.082	9.675LeuLeu: 9.675 ± 0.13	2.601LeuMet: 2.601 ± 0.048	4.061LeuAsn: 4.061 ± 0.05	3.915LeuPro: 3.915 ± 0.056	3.758LeuGln: 3.758 ± 0.059	3.589LeuArg: 3.589 ± 0.06	6.936LeuSer: 6.936 ± 0.094	5.541LeuThr: 5.541 ± 0.074	6.219LeuVal: 6.219 ± 0.082	0.933LeuTrp: 0.933 ± 0.033	3.341LeuTyr: 3.341 ± 0.06	0.0LeuXaa: 0.0 ± 0.0
Met	2.039MetAla: 2.039 ± 0.051	0.137MetCys: 0.137 ± 0.011	1.604MetAsp: 1.604 ± 0.035	2.026MetGlu: 2.026 ± 0.042	1.097MetPhe: 1.097 ± 0.037	1.904MetGly: 1.904 ± 0.048	0.436MetHis: 0.436 ± 0.019	2.216MetIle: 2.216 ± 0.044	2.595MetLys: 2.595 ± 0.046	2.46MetLeu: 2.46 ± 0.053	0.96MetMet: 0.96 ± 0.032	1.764MetAsn: 1.764 ± 0.039	1.043MetPro: 1.043 ± 0.042	0.94MetGln: 0.94 ± 0.029	1.192MetArg: 1.192 ± 0.031	1.792MetSer: 1.792 ± 0.039	1.665MetThr: 1.665 ± 0.04	1.965MetVal: 1.965 ± 0.051	0.23MetTrp: 0.23 ± 0.015	0.798MetTyr: 0.798 ± 0.026	0.0MetXaa: 0.0 ± 0.0
Asn	2.486AsnAla: 2.486 ± 0.052	0.213AsnCys: 0.213 ± 0.014	2.269AsnAsp: 2.269 ± 0.047	3.578AsnGlu: 3.578 ± 0.07	1.446AsnPhe: 1.446 ± 0.041	3.288AsnGly: 3.288 ± 0.059	1.036AsnHis: 1.036 ± 0.033	2.746AsnIle: 2.746 ± 0.047	2.444AsnLys: 2.444 ± 0.055	3.453AsnLeu: 3.453 ± 0.056	1.126AsnMet: 1.126 ± 0.03	1.623AsnAsn: 1.623 ± 0.058	1.934AsnPro: 1.934 ± 0.041	2.076AsnGln: 2.076 ± 0.049	1.982AsnArg: 1.982 ± 0.044	2.033AsnSer: 2.033 ± 0.055	2.007AsnThr: 2.007 ± 0.043	3.076AsnVal: 3.076 ± 0.053	0.498AsnTrp: 0.498 ± 0.021	1.392AsnTyr: 1.392 ± 0.04	0.0AsnXaa: 0.0 ± 0.0
Pro	2.192ProAla: 2.192 ± 0.049	0.188ProCys: 0.188 ± 0.014	2.225ProAsp: 2.225 ± 0.042	3.142ProGlu: 3.142 ± 0.065	2.156ProPhe: 2.156 ± 0.05	2.39ProGly: 2.39 ± 0.047	0.874ProHis: 0.874 ± 0.028	2.639ProIle: 2.639 ± 0.052	2.126ProLys: 2.126 ± 0.049	3.482ProLeu: 3.482 ± 0.057	0.915ProMet: 0.915 ± 0.032	1.586ProAsn: 1.586 ± 0.034	1.023ProPro: 1.023 ± 0.036	1.19ProGln: 1.19 ± 0.036	1.153ProArg: 1.153 ± 0.037	2.594ProSer: 2.594 ± 0.049	2.031ProThr: 2.031 ± 0.043	2.858ProVal: 2.858 ± 0.05	0.382ProTrp: 0.382 ± 0.021	1.625ProTyr: 1.625 ± 0.039	0.0ProXaa: 0.0 ± 0.0
Gln	2.879GlnAla: 2.879 ± 0.053	0.179GlnCys: 0.179 ± 0.013	2.286GlnAsp: 2.286 ± 0.05	3.655GlnGlu: 3.655 ± 0.111	1.716GlnPhe: 1.716 ± 0.043	2.417GlnGly: 2.417 ± 0.05	0.882GlnHis: 0.882 ± 0.03	2.346GlnIle: 2.346 ± 0.051	2.787GlnLys: 2.787 ± 0.052	4.082GlnLeu: 4.082 ± 0.074	1.318GlnMet: 1.318 ± 0.037	1.765GlnAsn: 1.765 ± 0.046	1.387GlnPro: 1.387 ± 0.044	2.131GlnGln: 2.131 ± 0.063	1.572GlnArg: 1.572 ± 0.04	2.673GlnSer: 2.673 ± 0.057	2.225GlnThr: 2.225 ± 0.039	2.704GlnVal: 2.704 ± 0.058	0.466GlnTrp: 0.466 ± 0.02	1.585GlnTyr: 1.585 ± 0.045	0.0GlnXaa: 0.0 ± 0.0
Arg	2.441ArgAla: 2.441 ± 0.04	0.254ArgCys: 0.254 ± 0.016	2.213ArgAsp: 2.213 ± 0.052	3.397ArgGlu: 3.397 ± 0.064	1.946ArgPhe: 1.946 ± 0.049	2.448ArgGly: 2.448 ± 0.045	0.84ArgHis: 0.84 ± 0.029	2.985ArgIle: 2.985 ± 0.056	2.985ArgLys: 2.985 ± 0.058	4.013ArgLeu: 4.013 ± 0.064	1.297ArgMet: 1.297 ± 0.031	1.873ArgAsn: 1.873 ± 0.043	1.313ArgPro: 1.313 ± 0.039	1.553ArgGln: 1.553 ± 0.045	1.796ArgArg: 1.796 ± 0.04	2.608ArgSer: 2.608 ± 0.054	2.195ArgThr: 2.195 ± 0.045	2.938ArgVal: 2.938 ± 0.057	0.433ArgTrp: 0.433 ± 0.02	1.709ArgTyr: 1.709 ± 0.043	0.0ArgXaa: 0.0 ± 0.0
Ser	3.552SerAla: 3.552 ± 0.06	0.349SerCys: 0.349 ± 0.017	2.981SerAsp: 2.981 ± 0.052	4.419SerGlu: 4.419 ± 0.064	3.473SerPhe: 3.473 ± 0.067	4.487SerGly: 4.487 ± 0.068	1.32SerHis: 1.32 ± 0.036	5.065SerIle: 5.065 ± 0.064	3.709SerLys: 3.709 ± 0.059	6.554SerLeu: 6.554 ± 0.09	1.921SerMet: 1.921 ± 0.045	2.475SerAsn: 2.475 ± 0.049	2.253SerPro: 2.253 ± 0.044	2.166SerGln: 2.166 ± 0.052	2.318SerArg: 2.318 ± 0.045	4.375SerSer: 4.375 ± 0.079	3.265SerThr: 3.265 ± 0.052	4.581SerVal: 4.581 ± 0.075	0.693SerTrp: 0.693 ± 0.031	2.533SerTyr: 2.533 ± 0.049	0.0SerXaa: 0.0 ± 0.0
Thr	3.546ThrAla: 3.546 ± 0.067	0.339ThrCys: 0.339 ± 0.016	2.757ThrAsp: 2.757 ± 0.055	3.692ThrGlu: 3.692 ± 0.06	2.902ThrPhe: 2.902 ± 0.056	4.064ThrGly: 4.064 ± 0.069	1.168ThrHis: 1.168 ± 0.034	4.476ThrIle: 4.476 ± 0.073	3.173ThrLys: 3.173 ± 0.052	5.562ThrLeu: 5.562 ± 0.076	1.396ThrMet: 1.396 ± 0.038	2.324ThrAsn: 2.324 ± 0.05	2.406ThrPro: 2.406 ± 0.053	1.67ThrGln: 1.67 ± 0.04	1.874ThrArg: 1.874 ± 0.036	3.633ThrSer: 3.633 ± 0.062	3.057ThrThr: 3.057 ± 0.058	4.115ThrVal: 4.115 ± 0.069	0.57ThrTrp: 0.57 ± 0.024	2.224ThrTyr: 2.224 ± 0.045	0.0ThrXaa: 0.0 ± 0.0
Val	5.08ValAla: 5.08 ± 0.074	0.513ValCys: 0.513 ± 0.024	4.134ValAsp: 4.134 ± 0.066	5.265ValGlu: 5.265 ± 0.078	3.223ValPhe: 3.223 ± 0.056	4.893ValGly: 4.893 ± 0.071	1.542ValHis: 1.542 ± 0.033	5.121ValIle: 5.121 ± 0.075	4.359ValLys: 4.359 ± 0.069	6.982ValLeu: 6.982 ± 0.091	2.105ValMet: 2.105 ± 0.04	2.955ValAsn: 2.955 ± 0.05	2.776ValPro: 2.776 ± 0.051	2.734ValGln: 2.734 ± 0.05	2.858ValArg: 2.858 ± 0.055	4.753ValSer: 4.753 ± 0.067	4.469ValThr: 4.469 ± 0.07	5.453ValVal: 5.453 ± 0.074	0.682ValTrp: 0.682 ± 0.028	2.503ValTyr: 2.503 ± 0.055	0.0ValXaa: 0.0 ± 0.0
Trp	0.616TrpAla: 0.616 ± 0.026	0.067TrpCys: 0.067 ± 0.008	0.564TrpAsp: 0.564 ± 0.023	0.751TrpGlu: 0.751 ± 0.027	0.606TrpPhe: 0.606 ± 0.026	0.75TrpGly: 0.75 ± 0.034	0.204TrpHis: 0.204 ± 0.015	0.89TrpIle: 0.89 ± 0.032	0.777TrpLys: 0.777 ± 0.027	1.178TrpLeu: 1.178 ± 0.035	0.418TrpMet: 0.418 ± 0.02	0.512TrpAsn: 0.512 ± 0.022	0.265TrpPro: 0.265 ± 0.015	0.363TrpGln: 0.363 ± 0.02	0.409TrpArg: 0.409 ± 0.021	0.637TrpSer: 0.637 ± 0.023	0.596TrpThr: 0.596 ± 0.026	0.803TrpVal: 0.803 ± 0.03	0.179TrpTrp: 0.179 ± 0.016	0.399TrpTyr: 0.399 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.152TyrAla: 2.152 ± 0.05	0.29TyrCys: 0.29 ± 0.017	2.096TyrAsp: 2.096 ± 0.043	2.876TyrGlu: 2.876 ± 0.057	1.824TyrPhe: 1.824 ± 0.043	2.67TyrGly: 2.67 ± 0.051	0.929TyrHis: 0.929 ± 0.026	2.362TyrIle: 2.362 ± 0.056	2.196TyrLys: 2.196 ± 0.048	3.332TyrLeu: 3.332 ± 0.058	1.004TyrMet: 1.004 ± 0.03	1.519TyrAsn: 1.519 ± 0.039	1.476TyrPro: 1.476 ± 0.039	1.693TyrGln: 1.693 ± 0.041	1.621TyrArg: 1.621 ± 0.043	2.159TyrSer: 2.159 ± 0.05	1.944TyrThr: 1.944 ± 0.05	2.528TyrVal: 2.528 ± 0.055	0.424TyrTrp: 0.424 ± 0.022	1.548TyrTyr: 1.548 ± 0.046	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3684 proteins (1063223 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---