Human papillomavirus 30

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae; Alphapapillomavirus; Alphapapillomavirus 6

Average proteome isoelectric point is 6.44

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 6 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>sp|Q02515|VL1_HPV30 Major capsid protein L1 OS=Human papillomavirus 30 OX=10611 GN=L1 PE=3 SV=2
MM1 pKa = 7.26HH2 pKa = 7.26GKK4 pKa = 8.24VTTIPEE10 pKa = 4.49YY11 pKa = 10.61ILDD14 pKa = 4.54LVPQTEE20 pKa = 4.41IDD22 pKa = 3.62LHH24 pKa = 8.58CYY26 pKa = 8.12EE27 pKa = 4.66QLNSSEE33 pKa = 4.99EE34 pKa = 4.03EE35 pKa = 4.57DD36 pKa = 3.66EE37 pKa = 5.83DD38 pKa = 5.47EE39 pKa = 5.06VDD41 pKa = 4.34NLQKK45 pKa = 10.46QPQQARR51 pKa = 11.84QEE53 pKa = 4.29EE54 pKa = 4.25QHH56 pKa = 6.44PCYY59 pKa = 10.46LINTQCCRR67 pKa = 11.84CASAVQLAVQSPTKK81 pKa = 9.77EE82 pKa = 3.81LRR84 pKa = 11.84ALQQMLMGALEE95 pKa = 4.51LVCPLCATRR104 pKa = 11.84RR105 pKa = 3.74

Molecular weight: 12.0 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>sp|P36826|VE7_HPV30 Protein E7 OS=Human papillomavirus 30 OX=10611 GN=E7 PE=3 SV=1
MM1 pKa = 7.57AFKK4 pKa = 10.8FEE6 pKa = 4.42NTGEE10 pKa = 4.11RR11 pKa = 11.84PRR13 pKa = 11.84TVHH16 pKa = 6.46HH17 pKa = 6.37LCEE20 pKa = 4.14VQEE23 pKa = 4.21TSLLEE28 pKa = 4.01LQLQCVYY35 pKa = 10.43CKK37 pKa = 10.54KK38 pKa = 9.84EE39 pKa = 3.85LSSSEE44 pKa = 4.34VYY46 pKa = 10.79NFACKK51 pKa = 10.17DD52 pKa = 3.18LRR54 pKa = 11.84LVYY57 pKa = 10.56RR58 pKa = 11.84EE59 pKa = 4.06DD60 pKa = 3.34SPYY63 pKa = 11.08AVCNFCLLFYY73 pKa = 11.06SKK75 pKa = 10.31VRR77 pKa = 11.84KK78 pKa = 8.81IRR80 pKa = 11.84HH81 pKa = 5.34YY82 pKa = 10.9NYY84 pKa = 10.5SLYY87 pKa = 10.65GASLVALTKK96 pKa = 10.53KK97 pKa = 10.4EE98 pKa = 4.11LFDD101 pKa = 4.82LLIRR105 pKa = 11.84CYY107 pKa = 10.36RR108 pKa = 11.84CQQPLTPEE116 pKa = 4.31EE117 pKa = 4.21KK118 pKa = 10.1QLHH121 pKa = 5.89CEE123 pKa = 3.91YY124 pKa = 10.6KK125 pKa = 10.49KK126 pKa = 10.36RR127 pKa = 11.84FHH129 pKa = 6.96RR130 pKa = 11.84ISRR133 pKa = 11.84TWTGLCLQCWRR144 pKa = 11.84HH145 pKa = 4.3TTSTEE150 pKa = 3.93TAVV153 pKa = 3.15

Molecular weight: 18.27 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

6

0

6

2238

105

631

373.0

42.05

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

5.853 ± 0.543

2.86 ± 0.742

5.541 ± 0.694

5.183 ± 0.78

3.798 ± 0.653

5.496 ± 0.61

2.636 ± 0.333

4.647 ± 0.584

5.362 ± 0.914

7.373 ± 0.872

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.877 ± 0.304

4.558 ± 0.74

5.853 ± 1.101

5.273 ± 0.867

4.96 ± 0.406

7.328 ± 0.675

8.222 ± 1.061

7.373 ± 0.818

1.519 ± 0.248

4.29 ± 0.601
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski