Amino acid dipepetide frequency for Litchfieldia salsus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	4.507AlaAla: 4.507 ± 0.074	0.51AlaCys: 0.51 ± 0.023	2.835AlaAsp: 2.835 ± 0.054	4.021AlaGlu: 4.021 ± 0.063	2.974AlaPhe: 2.974 ± 0.053	4.644AlaGly: 4.644 ± 0.077	1.134AlaHis: 1.134 ± 0.032	5.6AlaIle: 5.6 ± 0.071	4.164AlaLys: 4.164 ± 0.07	6.345AlaLeu: 6.345 ± 0.073	1.767AlaMet: 1.767 ± 0.041	2.699AlaAsn: 2.699 ± 0.048	1.867AlaPro: 1.867 ± 0.045	1.888AlaGln: 1.888 ± 0.044	2.324AlaArg: 2.324 ± 0.043	3.75AlaSer: 3.75 ± 0.054	3.394AlaThr: 3.394 ± 0.06	4.536AlaVal: 4.536 ± 0.066	0.588AlaTrp: 0.588 ± 0.023	2.048AlaTyr: 2.048 ± 0.037	0.0AlaXaa: 0.0 ± 0.0
Cys	0.379CysAla: 0.379 ± 0.019	0.111CysCys: 0.111 ± 0.008	0.367CysAsp: 0.367 ± 0.019	0.479CysGlu: 0.479 ± 0.019	0.312CysPhe: 0.312 ± 0.015	0.601CysGly: 0.601 ± 0.021	0.196CysHis: 0.196 ± 0.013	0.575CysIle: 0.575 ± 0.021	0.383CysLys: 0.383 ± 0.019	0.652CysLeu: 0.652 ± 0.024	0.161CysMet: 0.161 ± 0.012	0.305CysAsn: 0.305 ± 0.014	0.32CysPro: 0.32 ± 0.016	0.21CysGln: 0.21 ± 0.013	0.277CysArg: 0.277 ± 0.016	0.552CysSer: 0.552 ± 0.021	0.372CysThr: 0.372 ± 0.018	0.382CysVal: 0.382 ± 0.018	0.076CysTrp: 0.076 ± 0.008	0.285CysTyr: 0.285 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	2.849AspAla: 2.849 ± 0.055	0.396AspCys: 0.396 ± 0.02	2.424AspAsp: 2.424 ± 0.047	4.364AspGlu: 4.364 ± 0.063	2.41AspPhe: 2.41 ± 0.048	3.44AspGly: 3.44 ± 0.072	1.241AspHis: 1.241 ± 0.033	4.161AspIle: 4.161 ± 0.057	3.135AspLys: 3.135 ± 0.047	5.248AspLeu: 5.248 ± 0.069	1.217AspMet: 1.217 ± 0.027	1.875AspAsn: 1.875 ± 0.041	2.024AspPro: 2.024 ± 0.055	2.158AspGln: 2.158 ± 0.044	2.142AspArg: 2.142 ± 0.038	2.907AspSer: 2.907 ± 0.049	2.496AspThr: 2.496 ± 0.042	3.677AspVal: 3.677 ± 0.051	0.662AspTrp: 0.662 ± 0.021	2.241AspTyr: 2.241 ± 0.048	0.0AspXaa: 0.0 ± 0.0
Glu	4.731GluAla: 4.731 ± 0.069	0.386GluCys: 0.386 ± 0.021	3.925GluAsp: 3.925 ± 0.06	7.126GluGlu: 7.126 ± 0.088	2.778GluPhe: 2.778 ± 0.045	4.445GluGly: 4.445 ± 0.059	1.564GluHis: 1.564 ± 0.038	6.232GluIle: 6.232 ± 0.072	6.129GluLys: 6.129 ± 0.073	7.533GluLeu: 7.533 ± 0.086	2.281GluMet: 2.281 ± 0.044	3.932GluAsn: 3.932 ± 0.058	1.896GluPro: 1.896 ± 0.041	3.27GluGln: 3.27 ± 0.06	3.225GluArg: 3.225 ± 0.057	3.756GluSer: 3.756 ± 0.053	3.949GluThr: 3.949 ± 0.053	5.375GluVal: 5.375 ± 0.069	0.826GluTrp: 0.826 ± 0.025	2.536GluTyr: 2.536 ± 0.044	0.0GluXaa: 0.0 ± 0.0
Phe	2.776PheAla: 2.776 ± 0.048	0.361PheCys: 0.361 ± 0.016	2.492PheAsp: 2.492 ± 0.045	3.02PheGlu: 3.02 ± 0.046	2.495PhePhe: 2.495 ± 0.055	3.24PheGly: 3.24 ± 0.059	0.972PheHis: 0.972 ± 0.029	4.303PheIle: 4.303 ± 0.079	2.661PheLys: 2.661 ± 0.044	4.663PheLeu: 4.663 ± 0.075	1.191PheMet: 1.191 ± 0.032	2.227PheAsn: 2.227 ± 0.041	1.667PhePro: 1.667 ± 0.036	1.511PheGln: 1.511 ± 0.036	1.465PheArg: 1.465 ± 0.038	3.317PheSer: 3.317 ± 0.053	2.651PheThr: 2.651 ± 0.05	3.082PheVal: 3.082 ± 0.05	0.5PheTrp: 0.5 ± 0.023	1.769PheTyr: 1.769 ± 0.041	0.0PheXaa: 0.0 ± 0.0
Gly	4.36GlyAla: 4.36 ± 0.071	0.615GlyCys: 0.615 ± 0.024	3.221GlyAsp: 3.221 ± 0.054	4.542GlyGlu: 4.542 ± 0.065	3.451GlyPhe: 3.451 ± 0.058	4.669GlyGly: 4.669 ± 0.081	1.335GlyHis: 1.335 ± 0.029	6.077GlyIle: 6.077 ± 0.073	4.861GlyLys: 4.861 ± 0.068	6.631GlyLeu: 6.631 ± 0.085	1.933GlyMet: 1.933 ± 0.043	2.869GlyAsn: 2.869 ± 0.06	1.706GlyPro: 1.706 ± 0.05	2.211GlyGln: 2.211 ± 0.046	2.463GlyArg: 2.463 ± 0.046	4.002GlySer: 4.002 ± 0.057	3.964GlyThr: 3.964 ± 0.066	4.946GlyVal: 4.946 ± 0.074	0.837GlyTrp: 0.837 ± 0.032	2.899GlyTyr: 2.899 ± 0.053	0.0GlyXaa: 0.0 ± 0.0
His	1.156HisAla: 1.156 ± 0.03	0.194HisCys: 0.194 ± 0.012	1.026HisAsp: 1.026 ± 0.027	1.389HisGlu: 1.389 ± 0.035	1.116HisPhe: 1.116 ± 0.03	1.373HisGly: 1.373 ± 0.035	0.668HisHis: 0.668 ± 0.022	1.521HisIle: 1.521 ± 0.034	1.08HisLys: 1.08 ± 0.033	2.13HisLeu: 2.13 ± 0.035	0.432HisMet: 0.432 ± 0.017	0.878HisAsn: 0.878 ± 0.028	1.052HisPro: 1.052 ± 0.029	0.829HisGln: 0.829 ± 0.024	0.795HisArg: 0.795 ± 0.023	1.323HisSer: 1.323 ± 0.031	1.098HisThr: 1.098 ± 0.029	1.349HisVal: 1.349 ± 0.03	0.23HisTrp: 0.23 ± 0.014	0.883HisTyr: 0.883 ± 0.024	0.0HisXaa: 0.0 ± 0.0
Ile	5.715IleAla: 5.715 ± 0.086	0.637IleCys: 0.637 ± 0.024	4.702IleAsp: 4.702 ± 0.069	6.449IleGlu: 6.449 ± 0.068	3.474IlePhe: 3.474 ± 0.059	6.217IleGly: 6.217 ± 0.09	1.716IleHis: 1.716 ± 0.033	6.817IleIle: 6.817 ± 0.107	5.2IleLys: 5.2 ± 0.061	7.651IleLeu: 7.651 ± 0.104	1.856IleMet: 1.856 ± 0.038	4.014IleAsn: 4.014 ± 0.056	3.452IlePro: 3.452 ± 0.055	2.843IleGln: 2.843 ± 0.05	3.057IleArg: 3.057 ± 0.048	5.772IleSer: 5.772 ± 0.066	4.836IleThr: 4.836 ± 0.059	5.776IleVal: 5.776 ± 0.075	0.701IleTrp: 0.701 ± 0.024	2.79IleTyr: 2.79 ± 0.048	0.0IleXaa: 0.0 ± 0.0
Lys	4.07LysAla: 4.07 ± 0.062	0.338LysCys: 0.338 ± 0.017	3.819LysAsp: 3.819 ± 0.057	6.86LysGlu: 6.86 ± 0.082	1.987LysPhe: 1.987 ± 0.043	4.403LysGly: 4.403 ± 0.06	1.335LysHis: 1.335 ± 0.034	5.009LysIle: 5.009 ± 0.068	5.655LysLys: 5.655 ± 0.082	5.878LysLeu: 5.878 ± 0.074	2.133LysMet: 2.133 ± 0.041	3.575LysAsn: 3.575 ± 0.053	2.126LysPro: 2.126 ± 0.04	2.958LysGln: 2.958 ± 0.047	3.054LysArg: 3.054 ± 0.049	3.882LysSer: 3.882 ± 0.065	3.456LysThr: 3.456 ± 0.05	4.933LysVal: 4.933 ± 0.066	0.792LysTrp: 0.792 ± 0.022	2.3LysTyr: 2.3 ± 0.045	0.0LysXaa: 0.0 ± 0.0
Leu	6.478LeuAla: 6.478 ± 0.075	0.67LeuCys: 0.67 ± 0.025	4.769LeuAsp: 4.769 ± 0.064	6.763LeuGlu: 6.763 ± 0.086	5.07LeuPhe: 5.07 ± 0.088	6.351LeuGly: 6.351 ± 0.086	1.828LeuHis: 1.828 ± 0.037	7.947LeuIle: 7.947 ± 0.115	6.617LeuLys: 6.617 ± 0.081	10.266LeuLeu: 10.266 ± 0.122	2.434LeuMet: 2.434 ± 0.045	4.772LeuAsn: 4.772 ± 0.057	3.722LeuPro: 3.722 ± 0.055	3.387LeuGln: 3.387 ± 0.052	3.439LeuArg: 3.439 ± 0.056	7.197LeuSer: 7.197 ± 0.086	5.803LeuThr: 5.803 ± 0.071	6.507LeuVal: 6.507 ± 0.079	0.842LeuTrp: 0.842 ± 0.029	3.291LeuTyr: 3.291 ± 0.053	0.0LeuXaa: 0.0 ± 0.0
Met	1.716MetAla: 1.716 ± 0.039	0.134MetCys: 0.134 ± 0.01	1.354MetAsp: 1.354 ± 0.035	1.818MetGlu: 1.818 ± 0.037	1.099MetPhe: 1.099 ± 0.032	1.643MetGly: 1.643 ± 0.036	0.388MetHis: 0.388 ± 0.016	2.427MetIle: 2.427 ± 0.047	2.441MetLys: 2.441 ± 0.045	2.364MetLeu: 2.364 ± 0.047	0.817MetMet: 0.817 ± 0.03	1.714MetAsn: 1.714 ± 0.035	0.845MetPro: 0.845 ± 0.03	0.749MetGln: 0.749 ± 0.027	0.975MetArg: 0.975 ± 0.028	1.734MetSer: 1.734 ± 0.037	1.612MetThr: 1.612 ± 0.036	1.816MetVal: 1.816 ± 0.04	0.186MetTrp: 0.186 ± 0.012	0.758MetTyr: 0.758 ± 0.023	0.0MetXaa: 0.0 ± 0.0
Asn	2.521AsnAla: 2.521 ± 0.043	0.311AsnCys: 0.311 ± 0.015	2.519AsnAsp: 2.519 ± 0.05	4.133AsnGlu: 4.133 ± 0.062	1.757AsnPhe: 1.757 ± 0.042	3.56AsnGly: 3.56 ± 0.064	1.272AsnHis: 1.272 ± 0.03	3.749AsnIle: 3.749 ± 0.056	3.276AsnLys: 3.276 ± 0.046	4.221AsnLeu: 4.221 ± 0.058	1.268AsnMet: 1.268 ± 0.03	2.399AsnAsn: 2.399 ± 0.045	2.257AsnPro: 2.257 ± 0.044	2.244AsnGln: 2.244 ± 0.046	2.069AsnArg: 2.069 ± 0.046	2.795AsnSer: 2.795 ± 0.05	2.452AsnThr: 2.452 ± 0.05	3.175AsnVal: 3.175 ± 0.048	0.587AsnTrp: 0.587 ± 0.021	1.847AsnTyr: 1.847 ± 0.044	0.0AsnXaa: 0.0 ± 0.0
Pro	1.907ProAla: 1.907 ± 0.046	0.209ProCys: 0.209 ± 0.013	1.837ProAsp: 1.837 ± 0.038	2.744ProGlu: 2.744 ± 0.046	1.92ProPhe: 1.92 ± 0.04	2.202ProGly: 2.202 ± 0.057	0.724ProHis: 0.724 ± 0.024	2.979ProIle: 2.979 ± 0.048	2.11ProLys: 2.11 ± 0.04	3.411ProLeu: 3.411 ± 0.049	0.819ProMet: 0.819 ± 0.029	1.81ProAsn: 1.81 ± 0.041	0.937ProPro: 0.937 ± 0.03	1.052ProGln: 1.052 ± 0.031	1.041ProArg: 1.041 ± 0.026	2.397ProSer: 2.397 ± 0.042	2.177ProThr: 2.177 ± 0.046	2.695ProVal: 2.695 ± 0.051	0.358ProTrp: 0.358 ± 0.018	1.46ProTyr: 1.46 ± 0.038	0.0ProXaa: 0.0 ± 0.0
Gln	2.347GlnAla: 2.347 ± 0.046	0.19GlnCys: 0.19 ± 0.012	1.709GlnAsp: 1.709 ± 0.041	2.722GlnGlu: 2.722 ± 0.051	1.629GlnPhe: 1.629 ± 0.038	2.161GlnGly: 2.161 ± 0.046	0.748GlnHis: 0.748 ± 0.021	2.757GlnIle: 2.757 ± 0.049	2.565GlnLys: 2.565 ± 0.049	3.961GlnLeu: 3.961 ± 0.069	1.081GlnMet: 1.081 ± 0.029	1.633GlnAsn: 1.633 ± 0.039	1.176GlnPro: 1.176 ± 0.034	1.697GlnGln: 1.697 ± 0.05	1.35GlnArg: 1.35 ± 0.032	2.273GlnSer: 2.273 ± 0.047	1.993GlnThr: 1.993 ± 0.037	2.398GlnVal: 2.398 ± 0.044	0.382GlnTrp: 0.382 ± 0.019	1.368GlnTyr: 1.368 ± 0.03	0.0GlnXaa: 0.0 ± 0.0
Arg	2.168ArgAla: 2.168 ± 0.034	0.241ArgCys: 0.241 ± 0.013	2.009ArgAsp: 2.009 ± 0.036	2.977ArgGlu: 2.977 ± 0.047	1.822ArgPhe: 1.822 ± 0.036	2.227ArgGly: 2.227 ± 0.046	0.735ArgHis: 0.735 ± 0.024	3.046ArgIle: 3.046 ± 0.054	2.973ArgLys: 2.973 ± 0.054	3.767ArgLeu: 3.767 ± 0.052	1.135ArgMet: 1.135 ± 0.03	1.94ArgAsn: 1.94 ± 0.045	1.174ArgPro: 1.174 ± 0.03	1.331ArgGln: 1.331 ± 0.037	1.563ArgArg: 1.563 ± 0.039	2.168ArgSer: 2.168 ± 0.045	1.952ArgThr: 1.952 ± 0.037	2.463ArgVal: 2.463 ± 0.045	0.406ArgTrp: 0.406 ± 0.017	1.553ArgTyr: 1.553 ± 0.037	0.0ArgXaa: 0.0 ± 0.0
Ser	3.449SerAla: 3.449 ± 0.048	0.398SerCys: 0.398 ± 0.02	2.959SerAsp: 2.959 ± 0.049	4.424SerGlu: 4.424 ± 0.066	3.473SerPhe: 3.473 ± 0.059	4.322SerGly: 4.322 ± 0.058	1.278SerHis: 1.278 ± 0.033	5.909SerIle: 5.909 ± 0.071	4.195SerLys: 4.195 ± 0.063	6.396SerLeu: 6.396 ± 0.076	1.723SerMet: 1.723 ± 0.036	3.097SerAsn: 3.097 ± 0.051	2.171SerPro: 2.171 ± 0.039	2.129SerGln: 2.129 ± 0.044	2.235SerArg: 2.235 ± 0.037	4.46SerSer: 4.46 ± 0.066	3.622SerThr: 3.622 ± 0.062	4.349SerVal: 4.349 ± 0.059	0.709SerTrp: 0.709 ± 0.026	2.49SerTyr: 2.49 ± 0.048	0.0SerXaa: 0.0 ± 0.0
Thr	3.439ThrAla: 3.439 ± 0.057	0.372ThrCys: 0.372 ± 0.015	2.77ThrAsp: 2.77 ± 0.054	3.693ThrGlu: 3.693 ± 0.058	2.855ThrPhe: 2.855 ± 0.045	4.073ThrGly: 4.073 ± 0.059	1.058ThrHis: 1.058 ± 0.027	5.038ThrIle: 5.038 ± 0.059	3.437ThrLys: 3.437 ± 0.057	5.428ThrLeu: 5.428 ± 0.07	1.331ThrMet: 1.331 ± 0.031	2.858ThrAsn: 2.858 ± 0.049	2.248ThrPro: 2.248 ± 0.044	1.614ThrGln: 1.614 ± 0.033	1.787ThrArg: 1.787 ± 0.035	3.601ThrSer: 3.601 ± 0.064	3.172ThrThr: 3.172 ± 0.055	4.139ThrVal: 4.139 ± 0.055	0.543ThrTrp: 0.543 ± 0.018	2.13ThrTyr: 2.13 ± 0.048	0.0ThrXaa: 0.0 ± 0.0
Val	4.497ValAla: 4.497 ± 0.068	0.534ValCys: 0.534 ± 0.024	3.731ValAsp: 3.731 ± 0.062	5.02ValGlu: 5.02 ± 0.068	3.248ValPhe: 3.248 ± 0.052	4.756ValGly: 4.756 ± 0.072	1.238ValHis: 1.238 ± 0.027	5.996ValIle: 5.996 ± 0.07	4.64ValLys: 4.64 ± 0.054	6.719ValLeu: 6.719 ± 0.083	1.784ValMet: 1.784 ± 0.041	3.41ValAsn: 3.41 ± 0.065	2.469ValPro: 2.469 ± 0.047	2.176ValGln: 2.176 ± 0.037	2.431ValArg: 2.431 ± 0.035	4.785ValSer: 4.785 ± 0.064	4.127ValThr: 4.127 ± 0.062	4.955ValVal: 4.955 ± 0.066	0.61ValTrp: 0.61 ± 0.025	2.253ValTyr: 2.253 ± 0.044	0.0ValXaa: 0.0 ± 0.0
Trp	0.612TrpAla: 0.612 ± 0.023	0.078TrpCys: 0.078 ± 0.008	0.57TrpAsp: 0.57 ± 0.021	0.732TrpGlu: 0.732 ± 0.026	0.514TrpPhe: 0.514 ± 0.017	0.729TrpGly: 0.729 ± 0.023	0.193TrpHis: 0.193 ± 0.013	0.85TrpIle: 0.85 ± 0.025	0.731TrpLys: 0.731 ± 0.026	1.096TrpLeu: 1.096 ± 0.032	0.352TrpMet: 0.352 ± 0.017	0.616TrpAsn: 0.616 ± 0.022	0.242TrpPro: 0.242 ± 0.016	0.323TrpGln: 0.323 ± 0.014	0.394TrpArg: 0.394 ± 0.018	0.686TrpSer: 0.686 ± 0.025	0.497TrpThr: 0.497 ± 0.02	0.637TrpVal: 0.637 ± 0.026	0.152TrpTrp: 0.152 ± 0.01	0.391TrpTyr: 0.391 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.917TyrAla: 1.917 ± 0.035	0.312TyrCys: 0.312 ± 0.015	2.026TyrAsp: 2.026 ± 0.053	2.618TyrGlu: 2.618 ± 0.043	1.978TyrPhe: 1.978 ± 0.037	2.537TyrGly: 2.537 ± 0.055	0.896TyrHis: 0.896 ± 0.03	2.683TyrIle: 2.683 ± 0.05	2.312TyrLys: 2.312 ± 0.05	3.79TyrLeu: 3.79 ± 0.053	0.876TyrMet: 0.876 ± 0.026	1.786TyrAsn: 1.786 ± 0.043	1.438TyrPro: 1.438 ± 0.039	1.561TyrGln: 1.561 ± 0.036	1.564TyrArg: 1.564 ± 0.034	2.433TyrSer: 2.433 ± 0.046	1.964TyrThr: 1.964 ± 0.045	2.188TyrVal: 2.188 ± 0.042	0.412TyrTrp: 0.412 ± 0.017	1.551TyrTyr: 1.551 ± 0.04	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4559 proteins (1338924 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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