Amino acid dipepetide frequency for Uncultured phage WW-nAnB strain 3

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.93AlaAla: 2.93 ± 1.611
2.198AlaCys: 2.198 ± 0.729
3.663AlaAsp: 3.663 ± 0.834
0.733AlaGlu: 0.733 ± 0.686
0.733AlaPhe: 0.733 ± 0.562
3.663AlaGly: 3.663 ± 1.111
0.733AlaHis: 0.733 ± 0.564
2.93AlaIle: 2.93 ± 1.993
1.465AlaLys: 1.465 ± 1.124
6.593AlaLeu: 6.593 ± 2.222
0.733AlaMet: 0.733 ± 0.878
3.663AlaAsn: 3.663 ± 1.627
0.0AlaPro: 0.0 ± 0.0
3.663AlaGln: 3.663 ± 1.387
1.465AlaArg: 1.465 ± 0.834
7.326AlaSer: 7.326 ± 2.845
2.93AlaThr: 2.93 ± 1.702
8.059AlaVal: 8.059 ± 1.883
0.0AlaTrp: 0.0 ± 0.0
2.198AlaTyr: 2.198 ± 0.729
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.733CysCys: 0.733 ± 0.562
2.198CysAsp: 2.198 ± 0.892
0.733CysGlu: 0.733 ± 0.562
1.465CysPhe: 1.465 ± 0.984
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.733CysIle: 0.733 ± 0.878
1.465CysLys: 1.465 ± 0.834
1.465CysLeu: 1.465 ± 1.57
0.733CysMet: 0.733 ± 0.884
1.465CysAsn: 1.465 ± 1.141
2.198CysPro: 2.198 ± 1.104
0.0CysGln: 0.0 ± 0.0
2.198CysArg: 2.198 ± 1.014
0.733CysSer: 0.733 ± 0.884
0.0CysThr: 0.0 ± 0.0
2.198CysVal: 2.198 ± 0.892
0.733CysTrp: 0.733 ± 0.878
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.93AspAla: 2.93 ± 1.248
0.733AspCys: 0.733 ± 0.562
5.861AspAsp: 5.861 ± 3.112
2.93AspGlu: 2.93 ± 0.993
5.128AspPhe: 5.128 ± 1.676
5.128AspGly: 5.128 ± 1.537
0.0AspHis: 0.0 ± 0.0
3.663AspIle: 3.663 ± 1.629
2.93AspLys: 2.93 ± 2.272
4.396AspLeu: 4.396 ± 0.832
3.663AspMet: 3.663 ± 1.373
0.733AspAsn: 0.733 ± 0.878
2.93AspPro: 2.93 ± 2.247
0.0AspGln: 0.0 ± 0.0
1.465AspArg: 1.465 ± 1.033
8.791AspSer: 8.791 ± 2.775
3.663AspThr: 3.663 ± 1.554
2.93AspVal: 2.93 ± 1.236
2.93AspTrp: 2.93 ± 1.261
2.198AspTyr: 2.198 ± 0.729
0.0AspXaa: 0.0 ± 0.0
Glu
3.663GluAla: 3.663 ± 1.511
0.0GluCys: 0.0 ± 0.0
3.663GluAsp: 3.663 ± 1.517
2.93GluGlu: 2.93 ± 1.536
4.396GluPhe: 4.396 ± 1.35
2.198GluGly: 2.198 ± 0.892
0.733GluHis: 0.733 ± 0.878
2.198GluIle: 2.198 ± 1.223
3.663GluLys: 3.663 ± 1.629
7.326GluLeu: 7.326 ± 1.563
1.465GluMet: 1.465 ± 1.124
0.733GluAsn: 0.733 ± 0.562
1.465GluPro: 1.465 ± 1.033
2.93GluGln: 2.93 ± 1.562
3.663GluArg: 3.663 ± 2.08
2.198GluSer: 2.198 ± 0.729
3.663GluThr: 3.663 ± 1.375
3.663GluVal: 3.663 ± 1.224
0.0GluTrp: 0.0 ± 0.0
1.465GluTyr: 1.465 ± 1.755
0.0GluXaa: 0.0 ± 0.0
Phe
2.198PheAla: 2.198 ± 1.284
2.93PheCys: 2.93 ± 1.668
4.396PheAsp: 4.396 ± 0.832
2.198PheGlu: 2.198 ± 0.729
3.663PhePhe: 3.663 ± 2.713
6.593PheGly: 6.593 ± 5.414
1.465PheHis: 1.465 ± 1.128
3.663PheIle: 3.663 ± 3.614
2.198PheLys: 2.198 ± 1.825
5.861PheLeu: 5.861 ± 2.02
1.465PheMet: 1.465 ± 1.06
1.465PheAsn: 1.465 ± 0.909
1.465PhePro: 1.465 ± 0.882
0.733PheGln: 0.733 ± 0.564
1.465PheArg: 1.465 ± 1.124
10.256PheSer: 10.256 ± 3.521
1.465PheThr: 1.465 ± 1.648
5.861PheVal: 5.861 ± 3.735
2.198PheTrp: 2.198 ± 1.104
2.93PheTyr: 2.93 ± 1.346
0.0PheXaa: 0.0 ± 0.0
Gly
1.465GlyAla: 1.465 ± 0.673
0.733GlyCys: 0.733 ± 0.562
5.128GlyAsp: 5.128 ± 1.98
2.198GlyGlu: 2.198 ± 1.108
3.663GlyPhe: 3.663 ± 3.353
2.93GlyGly: 2.93 ± 1.815
2.93GlyHis: 2.93 ± 2.247
3.663GlyIle: 3.663 ± 1.811
1.465GlyLys: 1.465 ± 0.882
4.396GlyLeu: 4.396 ± 1.761
0.0GlyMet: 0.0 ± 0.0
1.465GlyAsn: 1.465 ± 1.544
0.733GlyPro: 0.733 ± 0.564
0.733GlyGln: 0.733 ± 0.878
4.396GlyArg: 4.396 ± 0.739
8.059GlySer: 8.059 ± 1.837
2.198GlyThr: 2.198 ± 1.74
2.93GlyVal: 2.93 ± 1.641
2.198GlyTrp: 2.198 ± 1.014
3.663GlyTyr: 3.663 ± 1.747
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.733HisAsp: 0.733 ± 0.564
0.733HisGlu: 0.733 ± 0.562
1.465HisPhe: 1.465 ± 1.124
0.733HisGly: 0.733 ± 0.562
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
0.733HisLys: 0.733 ± 0.686
3.663HisLeu: 3.663 ± 2.15
0.733HisMet: 0.733 ± 0.884
0.0HisAsn: 0.0 ± 0.0
0.0HisPro: 0.0 ± 0.0
0.0HisGln: 0.0 ± 0.0
1.465HisArg: 1.465 ± 0.834
2.198HisSer: 2.198 ± 0.723
0.733HisThr: 0.733 ± 0.562
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
0.733HisTyr: 0.733 ± 0.564
0.0HisXaa: 0.0 ± 0.0
Ile
2.93IleAla: 2.93 ± 2.066
0.0IleCys: 0.0 ± 0.0
2.93IleAsp: 2.93 ± 1.46
1.465IleGlu: 1.465 ± 1.124
3.663IlePhe: 3.663 ± 2.447
4.396IleGly: 4.396 ± 2.374
0.733IleHis: 0.733 ± 0.562
4.396IleIle: 4.396 ± 1.047
1.465IleLys: 1.465 ± 1.373
5.128IleLeu: 5.128 ± 2.156
0.733IleMet: 0.733 ± 0.686
0.733IleAsn: 0.733 ± 0.564
1.465IlePro: 1.465 ± 0.882
0.733IleGln: 0.733 ± 0.686
3.663IleArg: 3.663 ± 0.943
8.059IleSer: 8.059 ± 1.963
1.465IleThr: 1.465 ± 1.373
2.198IleVal: 2.198 ± 0.723
0.733IleTrp: 0.733 ± 0.686
2.93IleTyr: 2.93 ± 1.691
0.0IleXaa: 0.0 ± 0.0
Lys
3.663LysAla: 3.663 ± 0.753
0.0LysCys: 0.0 ± 0.0
1.465LysAsp: 1.465 ± 1.021
0.0LysGlu: 0.0 ± 0.0
3.663LysPhe: 3.663 ± 1.084
1.465LysGly: 1.465 ± 1.755
0.0LysHis: 0.0 ± 0.0
2.198LysIle: 2.198 ± 1.119
2.93LysLys: 2.93 ± 1.176
4.396LysLeu: 4.396 ± 1.882
2.198LysMet: 2.198 ± 2.111
1.465LysAsn: 1.465 ± 1.033
0.733LysPro: 0.733 ± 0.562
2.93LysGln: 2.93 ± 1.46
0.0LysArg: 0.0 ± 0.0
4.396LysSer: 4.396 ± 1.716
3.663LysThr: 3.663 ± 1.237
2.198LysVal: 2.198 ± 1.157
1.465LysTrp: 1.465 ± 0.834
2.198LysTyr: 2.198 ± 0.723
0.0LysXaa: 0.0 ± 0.0
Leu
4.396LeuAla: 4.396 ± 2.769
4.396LeuCys: 4.396 ± 1.892
6.593LeuAsp: 6.593 ± 3.323
2.198LeuGlu: 2.198 ± 2.633
8.059LeuPhe: 8.059 ± 3.048
4.396LeuGly: 4.396 ± 1.863
2.93LeuHis: 2.93 ± 0.993
5.128LeuIle: 5.128 ± 3.245
2.198LeuLys: 2.198 ± 0.729
9.524LeuLeu: 9.524 ± 3.201
1.465LeuMet: 1.465 ± 0.925
4.396LeuAsn: 4.396 ± 2.164
10.256LeuPro: 10.256 ± 2.318
2.93LeuGln: 2.93 ± 1.205
7.326LeuArg: 7.326 ± 2.049
7.326LeuSer: 7.326 ± 3.458
5.128LeuThr: 5.128 ± 1.253
5.861LeuVal: 5.861 ± 3.706
1.465LeuTrp: 1.465 ± 1.57
2.93LeuTyr: 2.93 ± 1.594
0.0LeuXaa: 0.0 ± 0.0
Met
0.733MetAla: 0.733 ± 0.884
0.0MetCys: 0.0 ± 0.0
2.198MetAsp: 2.198 ± 1.518
3.663MetGlu: 3.663 ± 1.088
0.0MetPhe: 0.0 ± 0.0
0.733MetGly: 0.733 ± 0.878
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.733MetLys: 0.733 ± 0.562
1.465MetLeu: 1.465 ± 1.28
0.733MetMet: 0.733 ± 0.686
0.733MetAsn: 0.733 ± 0.562
0.733MetPro: 0.733 ± 0.878
2.198MetGln: 2.198 ± 1.119
0.733MetArg: 0.733 ± 0.884
2.198MetSer: 2.198 ± 0.892
2.93MetThr: 2.93 ± 1.384
0.733MetVal: 0.733 ± 1.593
0.0MetTrp: 0.0 ± 0.0
1.465MetTyr: 1.465 ± 0.673
0.0MetXaa: 0.0 ± 0.0
Asn
2.198AsnAla: 2.198 ± 0.729
0.0AsnCys: 0.0 ± 0.0
0.0AsnAsp: 0.0 ± 0.0
1.465AsnGlu: 1.465 ± 1.124
2.93AsnPhe: 2.93 ± 2.87
3.663AsnGly: 3.663 ± 1.166
0.0AsnHis: 0.0 ± 0.0
1.465AsnIle: 1.465 ± 1.021
2.93AsnLys: 2.93 ± 0.993
1.465AsnLeu: 1.465 ± 0.771
0.733AsnMet: 0.733 ± 0.878
2.198AsnAsn: 2.198 ± 1.108
3.663AsnPro: 3.663 ± 2.683
1.465AsnGln: 1.465 ± 1.128
2.198AsnArg: 2.198 ± 1.617
5.861AsnSer: 5.861 ± 1.899
2.198AsnThr: 2.198 ± 0.938
2.198AsnVal: 2.198 ± 1.46
0.0AsnTrp: 0.0 ± 0.0
2.198AsnTyr: 2.198 ± 0.723
0.0AsnXaa: 0.0 ± 0.0
Pro
6.593ProAla: 6.593 ± 3.18
0.0ProCys: 0.0 ± 0.0
4.396ProAsp: 4.396 ± 0.832
6.593ProGlu: 6.593 ± 1.741
3.663ProPhe: 3.663 ± 1.224
0.0ProGly: 0.0 ± 0.0
0.733ProHis: 0.733 ± 0.562
0.0ProIle: 0.0 ± 0.0
0.733ProLys: 0.733 ± 0.878
3.663ProLeu: 3.663 ± 1.607
0.733ProMet: 0.733 ± 0.859
2.93ProAsn: 2.93 ± 1.702
0.0ProPro: 0.0 ± 0.0
1.465ProGln: 1.465 ± 0.771
1.465ProArg: 1.465 ± 0.834
5.128ProSer: 5.128 ± 1.912
0.733ProThr: 0.733 ± 0.562
2.198ProVal: 2.198 ± 1.346
0.733ProTrp: 0.733 ± 0.822
5.128ProTyr: 5.128 ± 1.554
0.0ProXaa: 0.0 ± 0.0
Gln
1.465GlnAla: 1.465 ± 1.373
0.733GlnCys: 0.733 ± 0.562
0.733GlnAsp: 0.733 ± 0.562
2.198GlnGlu: 2.198 ± 1.119
1.465GlnPhe: 1.465 ± 1.124
1.465GlnGly: 1.465 ± 1.124
0.733GlnHis: 0.733 ± 0.564
0.733GlnIle: 0.733 ± 0.564
0.733GlnLys: 0.733 ± 0.562
1.465GlnLeu: 1.465 ± 1.373
0.0GlnMet: 0.0 ± 0.0
2.93GlnAsn: 2.93 ± 1.659
0.733GlnPro: 0.733 ± 0.686
1.465GlnGln: 1.465 ± 0.771
1.465GlnArg: 1.465 ± 0.834
0.0GlnSer: 0.0 ± 0.0
2.198GlnThr: 2.198 ± 1.617
3.663GlnVal: 3.663 ± 1.365
0.733GlnTrp: 0.733 ± 0.564
4.396GlnTyr: 4.396 ± 1.701
0.0GlnXaa: 0.0 ± 0.0
Arg
2.93ArgAla: 2.93 ± 1.105
0.733ArgCys: 0.733 ± 0.884
2.93ArgAsp: 2.93 ± 1.764
3.663ArgGlu: 3.663 ± 1.754
0.0ArgPhe: 0.0 ± 0.0
0.733ArgGly: 0.733 ± 1.593
0.0ArgHis: 0.0 ± 0.0
4.396ArgIle: 4.396 ± 1.654
5.128ArgLys: 5.128 ± 1.509
3.663ArgLeu: 3.663 ± 1.38
0.733ArgMet: 0.733 ± 0.686
0.733ArgAsn: 0.733 ± 0.686
2.93ArgPro: 2.93 ± 1.261
0.0ArgGln: 0.0 ± 0.0
2.93ArgArg: 2.93 ± 1.236
5.861ArgSer: 5.861 ± 3.535
3.663ArgThr: 3.663 ± 1.224
1.465ArgVal: 1.465 ± 0.834
2.198ArgTrp: 2.198 ± 1.014
2.93ArgTyr: 2.93 ± 1.649
0.0ArgXaa: 0.0 ± 0.0
Ser
6.593SerAla: 6.593 ± 1.281
0.733SerCys: 0.733 ± 0.878
2.93SerAsp: 2.93 ± 1.624
5.861SerGlu: 5.861 ± 2.637
5.861SerPhe: 5.861 ± 3.62
8.791SerGly: 8.791 ± 3.225
0.733SerHis: 0.733 ± 0.884
5.128SerIle: 5.128 ± 2.151
3.663SerLys: 3.663 ± 2.414
14.652SerLeu: 14.652 ± 3.949
1.465SerMet: 1.465 ± 1.22
5.861SerAsn: 5.861 ± 3.14
9.524SerPro: 9.524 ± 3.797
4.396SerGln: 4.396 ± 1.75
4.396SerArg: 4.396 ± 1.302
11.722SerSer: 11.722 ± 4.71
4.396SerThr: 4.396 ± 1.948
8.059SerVal: 8.059 ± 1.562
0.733SerTrp: 0.733 ± 0.564
5.128SerTyr: 5.128 ± 1.538
0.0SerXaa: 0.0 ± 0.0
Thr
2.198ThrAla: 2.198 ± 1.601
0.733ThrCys: 0.733 ± 0.686
2.93ThrAsp: 2.93 ± 1.893
3.663ThrGlu: 3.663 ± 1.129
6.593ThrPhe: 6.593 ± 2.021
0.0ThrGly: 0.0 ± 0.0
0.0ThrHis: 0.0 ± 0.0
2.198ThrIle: 2.198 ± 1.667
1.465ThrLys: 1.465 ± 0.947
4.396ThrLeu: 4.396 ± 1.732
1.465ThrMet: 1.465 ± 1.755
0.0ThrAsn: 0.0 ± 0.0
2.93ThrPro: 2.93 ± 1.387
0.733ThrGln: 0.733 ± 0.562
0.0ThrArg: 0.0 ± 0.0
8.791ThrSer: 8.791 ± 2.72
2.93ThrThr: 2.93 ± 1.991
7.326ThrVal: 7.326 ± 2.932
1.465ThrTrp: 1.465 ± 1.373
0.733ThrTyr: 0.733 ± 0.564
0.0ThrXaa: 0.0 ± 0.0
Val
5.128ValAla: 5.128 ± 1.69
1.465ValCys: 1.465 ± 1.851
4.396ValAsp: 4.396 ± 1.625
5.128ValGlu: 5.128 ± 1.715
5.861ValPhe: 5.861 ± 2.984
3.663ValGly: 3.663 ± 2.268
0.733ValHis: 0.733 ± 0.686
3.663ValIle: 3.663 ± 1.018
2.198ValLys: 2.198 ± 1.072
5.861ValLeu: 5.861 ± 3.352
0.733ValMet: 0.733 ± 0.562
2.93ValAsn: 2.93 ± 0.993
3.663ValPro: 3.663 ± 1.898
2.198ValGln: 2.198 ± 1.346
3.663ValArg: 3.663 ± 1.018
7.326ValSer: 7.326 ± 1.764
2.93ValThr: 2.93 ± 1.512
4.396ValVal: 4.396 ± 0.883
1.465ValTrp: 1.465 ± 0.673
3.663ValTyr: 3.663 ± 0.778
0.0ValXaa: 0.0 ± 0.0
Trp
1.465TrpAla: 1.465 ± 1.128
1.465TrpCys: 1.465 ± 0.947
1.465TrpAsp: 1.465 ± 1.544
0.733TrpGlu: 0.733 ± 0.562
1.465TrpPhe: 1.465 ± 1.033
0.733TrpGly: 0.733 ± 0.686
0.0TrpHis: 0.0 ± 0.0
1.465TrpIle: 1.465 ± 0.771
0.733TrpLys: 0.733 ± 0.878
2.93TrpLeu: 2.93 ± 1.691
0.733TrpMet: 0.733 ± 0.751
1.465TrpAsn: 1.465 ± 0.673
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
2.198TrpArg: 2.198 ± 0.945
1.465TrpSer: 1.465 ± 0.673
0.0TrpThr: 0.0 ± 0.0
0.733TrpVal: 0.733 ± 0.686
1.465TrpTrp: 1.465 ± 0.979
0.733TrpTyr: 0.733 ± 0.878
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.198TyrAla: 2.198 ± 0.729
1.465TyrCys: 1.465 ± 1.28
4.396TyrAsp: 4.396 ± 1.161
2.93TyrGlu: 2.93 ± 1.075
0.733TyrPhe: 0.733 ± 0.958
3.663TyrGly: 3.663 ± 0.943
1.465TyrHis: 1.465 ± 0.882
2.198TyrIle: 2.198 ± 1.119
2.93TyrLys: 2.93 ± 1.07
6.593TyrLeu: 6.593 ± 2.185
0.733TyrMet: 0.733 ± 0.878
2.93TyrAsn: 2.93 ± 1.649
1.465TyrPro: 1.465 ± 0.673
0.733TyrGln: 0.733 ± 0.562
1.465TyrArg: 1.465 ± 0.834
2.93TyrSer: 2.93 ± 1.153
3.663TyrThr: 3.663 ± 1.414
4.396TyrVal: 4.396 ± 2.044
0.733TyrTrp: 0.733 ± 0.878
1.465TyrTyr: 1.465 ± 1.124
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 8 proteins (1366 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski