Amino acid dipepetide frequency for Propithecus coquereli (Coquerel s sifaka) (Propithecus verreauxi coquereli)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.179AlaAla: 7.179 ± 0.045	1.411AlaCys: 1.411 ± 0.013	3.013AlaAsp: 3.013 ± 0.015	4.899AlaGlu: 4.899 ± 0.029	2.624AlaPhe: 2.624 ± 0.015	4.913AlaGly: 4.913 ± 0.028	1.562AlaHis: 1.562 ± 0.011	2.773AlaIle: 2.773 ± 0.015	3.506AlaLys: 3.506 ± 0.026	7.239AlaLeu: 7.239 ± 0.03	1.524AlaMet: 1.524 ± 0.01	2.045AlaAsn: 2.045 ± 0.013	4.292AlaPro: 4.292 ± 0.03	3.33AlaGln: 3.33 ± 0.019	3.82AlaArg: 3.82 ± 0.02	5.744AlaSer: 5.744 ± 0.024	3.625AlaThr: 3.625 ± 0.02	4.744AlaVal: 4.744 ± 0.02	0.815AlaTrp: 0.815 ± 0.008	1.568AlaTyr: 1.568 ± 0.009	0.001AlaXaa: 0.001 ± 0.0
Cys	1.276CysAla: 1.276 ± 0.012	0.652CysCys: 0.652 ± 0.009	1.013CysAsp: 1.013 ± 0.013	1.27CysGlu: 1.27 ± 0.015	0.842CysPhe: 0.842 ± 0.007	1.709CysGly: 1.709 ± 0.018	0.666CysHis: 0.666 ± 0.007	0.939CysIle: 0.939 ± 0.009	1.137CysLys: 1.137 ± 0.01	2.148CysLeu: 2.148 ± 0.015	0.409CysMet: 0.409 ± 0.005	0.804CysAsn: 0.804 ± 0.009	1.389CysPro: 1.389 ± 0.018	1.054CysGln: 1.054 ± 0.013	1.312CysArg: 1.312 ± 0.012	1.955CysSer: 1.955 ± 0.017	1.057CysThr: 1.057 ± 0.01	1.327CysVal: 1.327 ± 0.013	0.289CysTrp: 0.289 ± 0.005	0.568CysTyr: 0.568 ± 0.007	0.0CysXaa: 0.0 ± 0.0
Asp	2.966AspAla: 2.966 ± 0.014	1.076AspCys: 1.076 ± 0.014	2.701AspAsp: 2.701 ± 0.017	3.519AspGlu: 3.519 ± 0.021	2.137AspPhe: 2.137 ± 0.011	3.399AspGly: 3.399 ± 0.022	1.14AspHis: 1.14 ± 0.009	2.597AspIle: 2.597 ± 0.013	2.571AspLys: 2.571 ± 0.014	5.022AspLeu: 5.022 ± 0.019	1.131AspMet: 1.131 ± 0.01	1.705AspAsn: 1.705 ± 0.011	2.963AspPro: 2.963 ± 0.017	1.835AspGln: 1.835 ± 0.01	2.481AspArg: 2.481 ± 0.018	4.156AspSer: 4.156 ± 0.017	2.452AspThr: 2.452 ± 0.012	3.122AspVal: 3.122 ± 0.017	0.636AspTrp: 0.636 ± 0.006	1.53AspTyr: 1.53 ± 0.011	0.0AspXaa: 0.0 ± 0.0
Glu	5.297GluAla: 5.297 ± 0.033	1.394GluCys: 1.394 ± 0.02	4.478GluAsp: 4.478 ± 0.019	7.99GluGlu: 7.99 ± 0.047	2.066GluPhe: 2.066 ± 0.012	4.225GluGly: 4.225 ± 0.021	1.518GluHis: 1.518 ± 0.012	3.138GluIle: 3.138 ± 0.019	5.317GluLys: 5.317 ± 0.035	6.504GluLeu: 6.504 ± 0.033	1.667GluMet: 1.667 ± 0.013	3.09GluAsn: 3.09 ± 0.017	3.28GluPro: 3.28 ± 0.019	3.179GluGln: 3.179 ± 0.019	4.105GluArg: 4.105 ± 0.031	4.302GluSer: 4.302 ± 0.018	3.355GluThr: 3.355 ± 0.02	4.192GluVal: 4.192 ± 0.017	0.699GluTrp: 0.699 ± 0.008	1.634GluTyr: 1.634 ± 0.012	0.0GluXaa: 0.0 ± 0.0
Phe	2.029PheAla: 2.029 ± 0.012	0.913PheCys: 0.913 ± 0.008	1.719PheAsp: 1.719 ± 0.011	2.035PheGlu: 2.035 ± 0.013	1.591PhePhe: 1.591 ± 0.012	2.214PheGly: 2.214 ± 0.013	1.029PheHis: 1.029 ± 0.009	1.8PheIle: 1.8 ± 0.012	1.792PheLys: 1.792 ± 0.012	4.053PheLeu: 4.053 ± 0.02	0.77PheMet: 0.77 ± 0.007	1.359PheAsn: 1.359 ± 0.01	2.007PhePro: 2.007 ± 0.013	1.788PheGln: 1.788 ± 0.011	1.983PheArg: 1.983 ± 0.012	3.389PheSer: 3.389 ± 0.016	1.991PheThr: 1.991 ± 0.012	2.181PheVal: 2.181 ± 0.013	0.488PheTrp: 0.488 ± 0.005	1.175PheTyr: 1.175 ± 0.009	0.0PheXaa: 0.0 ± 0.0
Gly	4.73GlyAla: 4.73 ± 0.028	1.273GlyCys: 1.273 ± 0.011	3.235GlyAsp: 3.235 ± 0.019	4.2GlyGlu: 4.2 ± 0.026	2.416GlyPhe: 2.416 ± 0.015	5.28GlyGly: 5.28 ± 0.038	1.699GlyHis: 1.699 ± 0.013	2.724GlyIle: 2.724 ± 0.015	3.796GlyLys: 3.796 ± 0.023	5.951GlyLeu: 5.951 ± 0.024	1.322GlyMet: 1.322 ± 0.011	2.333GlyAsn: 2.333 ± 0.014	4.45GlyPro: 4.45 ± 0.053	2.803GlyGln: 2.803 ± 0.017	3.887GlyArg: 3.887 ± 0.02	5.833GlySer: 5.833 ± 0.033	3.603GlyThr: 3.603 ± 0.019	3.598GlyVal: 3.598 ± 0.019	0.809GlyTrp: 0.809 ± 0.009	1.768GlyTyr: 1.768 ± 0.013	0.001GlyXaa: 0.001 ± 0.0
His	1.356HisAla: 1.356 ± 0.01	0.722HisCys: 0.722 ± 0.009	0.884HisAsp: 0.884 ± 0.009	1.326HisGlu: 1.326 ± 0.01	1.078HisPhe: 1.078 ± 0.01	1.565HisGly: 1.565 ± 0.009	0.906HisHis: 0.906 ± 0.011	1.231HisIle: 1.231 ± 0.009	1.243HisLys: 1.243 ± 0.008	2.869HisLeu: 2.869 ± 0.014	0.584HisMet: 0.584 ± 0.007	0.848HisAsn: 0.848 ± 0.007	1.662HisPro: 1.662 ± 0.011	1.326HisGln: 1.326 ± 0.012	1.614HisArg: 1.614 ± 0.011	2.256HisSer: 2.256 ± 0.012	1.469HisThr: 1.469 ± 0.012	1.514HisVal: 1.514 ± 0.01	0.337HisTrp: 0.337 ± 0.005	0.811HisTyr: 0.811 ± 0.007	0.0HisXaa: 0.0 ± 0.0
Ile	2.586IleAla: 2.586 ± 0.014	1.05IleCys: 1.05 ± 0.009	2.044IleAsp: 2.044 ± 0.013	2.612IleGlu: 2.612 ± 0.017	1.876IlePhe: 1.876 ± 0.011	2.22IleGly: 2.22 ± 0.014	1.305IleHis: 1.305 ± 0.011	2.309IleIle: 2.309 ± 0.016	2.598IleLys: 2.598 ± 0.016	4.453IleLeu: 4.453 ± 0.022	0.971IleMet: 0.971 ± 0.008	1.815IleAsn: 1.815 ± 0.012	2.577IlePro: 2.577 ± 0.014	2.25IleGln: 2.25 ± 0.015	2.406IleArg: 2.406 ± 0.015	3.585IleSer: 3.585 ± 0.015	2.509IleThr: 2.509 ± 0.015	2.516IleVal: 2.516 ± 0.014	0.497IleTrp: 0.497 ± 0.006	1.365IleTyr: 1.365 ± 0.01	0.0IleXaa: 0.0 ± 0.0
Lys	4.001LysAla: 4.001 ± 0.023	1.131LysCys: 1.131 ± 0.01	3.168LysAsp: 3.168 ± 0.018	5.038LysGlu: 5.038 ± 0.032	1.752LysPhe: 1.752 ± 0.01	3.272LysGly: 3.272 ± 0.022	1.403LysHis: 1.403 ± 0.011	2.75LysIle: 2.75 ± 0.017	4.665LysLys: 4.665 ± 0.029	5.134LysLeu: 5.134 ± 0.026	1.425LysMet: 1.425 ± 0.01	2.4LysAsn: 2.4 ± 0.016	3.057LysPro: 3.057 ± 0.017	2.593LysGln: 2.593 ± 0.017	3.328LysArg: 3.328 ± 0.017	3.826LysSer: 3.826 ± 0.021	3.041LysThr: 3.041 ± 0.017	3.457LysVal: 3.457 ± 0.016	0.603LysTrp: 0.603 ± 0.007	1.586LysTyr: 1.586 ± 0.013	0.0LysXaa: 0.0 ± 0.0
Leu	6.901LeuAla: 6.901 ± 0.026	2.188LeuCys: 2.188 ± 0.014	4.78LeuAsp: 4.78 ± 0.019	7.14LeuGlu: 7.14 ± 0.034	3.393LeuPhe: 3.393 ± 0.019	5.964LeuGly: 5.964 ± 0.024	2.728LeuHis: 2.728 ± 0.015	3.809LeuIle: 3.809 ± 0.019	5.734LeuLys: 5.734 ± 0.028	10.783LeuLeu: 10.783 ± 0.044	1.995LeuMet: 1.995 ± 0.012	3.462LeuAsn: 3.462 ± 0.018	5.995LeuPro: 5.995 ± 0.028	5.779LeuGln: 5.779 ± 0.029	6.042LeuArg: 6.042 ± 0.027	7.828LeuSer: 7.828 ± 0.025	5.014LeuThr: 5.014 ± 0.019	5.523LeuVal: 5.523 ± 0.024	1.128LeuTrp: 1.128 ± 0.009	2.537LeuTyr: 2.537 ± 0.015	0.001LeuXaa: 0.001 ± 0.0
Met	1.932MetAla: 1.932 ± 0.012	0.398MetCys: 0.398 ± 0.005	1.26MetAsp: 1.26 ± 0.009	1.854MetGlu: 1.854 ± 0.012	0.74MetPhe: 0.74 ± 0.007	1.294MetGly: 1.294 ± 0.012	0.461MetHis: 0.461 ± 0.005	0.825MetIle: 0.825 ± 0.006	1.434MetLys: 1.434 ± 0.01	1.951MetLeu: 1.951 ± 0.012	0.567MetMet: 0.567 ± 0.006	0.898MetAsn: 0.898 ± 0.009	1.093MetPro: 1.093 ± 0.009	0.914MetGln: 0.914 ± 0.009	1.067MetArg: 1.067 ± 0.008	1.551MetSer: 1.551 ± 0.01	1.088MetThr: 1.088 ± 0.007	1.397MetVal: 1.397 ± 0.009	0.24MetTrp: 0.24 ± 0.004	0.567MetTyr: 0.567 ± 0.006	0.0MetXaa: 0.0 ± 0.0
Asn	2.06AsnAla: 2.06 ± 0.013	0.823AsnCys: 0.823 ± 0.009	1.522AsnAsp: 1.522 ± 0.012	2.185AsnGlu: 2.185 ± 0.015	1.481AsnPhe: 1.481 ± 0.009	2.499AsnGly: 2.499 ± 0.02	0.944AsnHis: 0.944 ± 0.008	2.099AsnIle: 2.099 ± 0.013	2.177AsnLys: 2.177 ± 0.015	3.711AsnLeu: 3.711 ± 0.02	0.913AsnMet: 0.913 ± 0.009	1.527AsnAsn: 1.527 ± 0.012	2.178AsnPro: 2.178 ± 0.015	1.646AsnGln: 1.646 ± 0.01	1.843AsnArg: 1.843 ± 0.011	3.073AsnSer: 3.073 ± 0.019	1.925AsnThr: 1.925 ± 0.013	2.178AsnVal: 2.178 ± 0.014	0.446AsnTrp: 0.446 ± 0.005	1.122AsnTyr: 1.122 ± 0.01	0.0AsnXaa: 0.0 ± 0.0
Pro	5.051ProAla: 5.051 ± 0.033	1.14ProCys: 1.14 ± 0.015	2.818ProAsp: 2.818 ± 0.016	4.464ProGlu: 4.464 ± 0.023	1.91ProPhe: 1.91 ± 0.012	5.504ProGly: 5.504 ± 0.062	1.461ProHis: 1.461 ± 0.011	1.853ProIle: 1.853 ± 0.012	2.744ProLys: 2.744 ± 0.017	5.233ProLeu: 5.233 ± 0.026	1.039ProMet: 1.039 ± 0.01	1.822ProAsn: 1.822 ± 0.013	6.309ProPro: 6.309 ± 0.054	2.84ProGln: 2.84 ± 0.02	3.416ProArg: 3.416 ± 0.022	5.709ProSer: 5.709 ± 0.034	3.112ProThr: 3.112 ± 0.019	3.807ProVal: 3.807 ± 0.019	0.707ProTrp: 0.707 ± 0.007	1.512ProTyr: 1.512 ± 0.013	0.001ProXaa: 0.001 ± 0.0
Gln	3.567GlnAla: 3.567 ± 0.022	0.937GlnCys: 0.937 ± 0.012	2.337GlnAsp: 2.337 ± 0.012	3.866GlnGlu: 3.866 ± 0.023	1.386GlnPhe: 1.386 ± 0.009	2.89GlnGly: 2.89 ± 0.02	1.301GlnHis: 1.301 ± 0.01	1.983GlnIle: 1.983 ± 0.012	2.895GlnLys: 2.895 ± 0.018	4.749GlnLeu: 4.749 ± 0.023	1.111GlnMet: 1.111 ± 0.011	1.822GlnAsn: 1.822 ± 0.013	2.833GlnPro: 2.833 ± 0.022	3.152GlnGln: 3.152 ± 0.032	2.996GlnArg: 2.996 ± 0.019	3.095GlnSer: 3.095 ± 0.019	2.266GlnThr: 2.266 ± 0.014	2.827GlnVal: 2.827 ± 0.016	0.543GlnTrp: 0.543 ± 0.006	1.147GlnTyr: 1.147 ± 0.008	0.001GlnXaa: 0.001 ± 0.0
Arg	4.001ArgAla: 4.001 ± 0.021	1.262ArgCys: 1.262 ± 0.014	2.858ArgAsp: 2.858 ± 0.016	4.065ArgGlu: 4.065 ± 0.025	1.878ArgPhe: 1.878 ± 0.012	3.741ArgGly: 3.741 ± 0.025	1.544ArgHis: 1.544 ± 0.011	2.447ArgIle: 2.447 ± 0.013	3.689ArgLys: 3.689 ± 0.016	5.534ArgLeu: 5.534 ± 0.027	1.212ArgMet: 1.212 ± 0.01	2.118ArgAsn: 2.118 ± 0.012	3.296ArgPro: 3.296 ± 0.02	2.677ArgGln: 2.677 ± 0.015	4.456ArgArg: 4.456 ± 0.026	4.29ArgSer: 4.29 ± 0.024	2.848ArgThr: 2.848 ± 0.013	3.218ArgVal: 3.218 ± 0.016	0.705ArgTrp: 0.705 ± 0.007	1.475ArgTyr: 1.475 ± 0.01	0.001ArgXaa: 0.001 ± 0.0
Ser	5.349SerAla: 5.349 ± 0.02	1.812SerCys: 1.812 ± 0.015	3.893SerAsp: 3.893 ± 0.024	5.102SerGlu: 5.102 ± 0.022	2.996SerPhe: 2.996 ± 0.016	5.627SerGly: 5.627 ± 0.028	2.058SerHis: 2.058 ± 0.011	3.144SerIle: 3.144 ± 0.015	4.016SerLys: 4.016 ± 0.018	8.066SerLeu: 8.066 ± 0.028	1.559SerMet: 1.559 ± 0.011	2.665SerAsn: 2.665 ± 0.016	6.063SerPro: 6.063 ± 0.039	3.809SerGln: 3.809 ± 0.019	4.57SerArg: 4.57 ± 0.026	9.123SerSer: 9.123 ± 0.045	4.31SerThr: 4.31 ± 0.023	4.829SerVal: 4.829 ± 0.02	1.049SerTrp: 1.049 ± 0.01	2.073SerTyr: 2.073 ± 0.015	0.001SerXaa: 0.001 ± 0.0
Thr	3.762ThrAla: 3.762 ± 0.017	1.273ThrCys: 1.273 ± 0.014	2.441ThrAsp: 2.441 ± 0.014	3.471ThrGlu: 3.471 ± 0.021	2.074ThrPhe: 2.074 ± 0.012	3.523ThrGly: 3.523 ± 0.019	1.266ThrHis: 1.266 ± 0.01	2.336ThrIle: 2.336 ± 0.015	2.629ThrLys: 2.629 ± 0.014	5.245ThrLeu: 5.245 ± 0.02	1.102ThrMet: 1.102 ± 0.008	1.721ThrAsn: 1.721 ± 0.01	3.54ThrPro: 3.54 ± 0.022	2.225ThrGln: 2.225 ± 0.013	2.482ThrArg: 2.482 ± 0.013	4.504ThrSer: 4.504 ± 0.022	2.969ThrThr: 2.969 ± 0.022	3.82ThrVal: 3.82 ± 0.021	0.673ThrTrp: 0.673 ± 0.007	1.413ThrTyr: 1.413 ± 0.011	0.0ThrXaa: 0.0 ± 0.0
Val	4.347ValAla: 4.347 ± 0.02	1.439ValCys: 1.439 ± 0.014	2.997ValAsp: 2.997 ± 0.015	3.868ValGlu: 3.868 ± 0.018	2.402ValPhe: 2.402 ± 0.014	3.443ValGly: 3.443 ± 0.018	1.55ValHis: 1.55 ± 0.011	2.888ValIle: 2.888 ± 0.015	3.379ValLys: 3.379 ± 0.016	6.22ValLeu: 6.22 ± 0.021	1.307ValMet: 1.307 ± 0.009	2.269ValAsn: 2.269 ± 0.012	3.66ValPro: 3.66 ± 0.019	2.718ValGln: 2.718 ± 0.015	3.13ValArg: 3.13 ± 0.015	4.846ValSer: 4.846 ± 0.021	3.737ValThr: 3.737 ± 0.019	4.001ValVal: 4.001 ± 0.019	0.722ValTrp: 0.722 ± 0.007	1.64ValTyr: 1.64 ± 0.011	0.0ValXaa: 0.0 ± 0.0
Trp	0.809TrpAla: 0.809 ± 0.007	0.247TrpCys: 0.247 ± 0.004	0.655TrpAsp: 0.655 ± 0.007	0.808TrpGlu: 0.808 ± 0.008	0.444TrpPhe: 0.444 ± 0.006	0.738TrpGly: 0.738 ± 0.009	0.306TrpHis: 0.306 ± 0.005	0.535TrpIle: 0.535 ± 0.006	0.799TrpLys: 0.799 ± 0.007	1.217TrpLeu: 1.217 ± 0.009	0.315TrpMet: 0.315 ± 0.005	0.536TrpAsn: 0.536 ± 0.006	0.518TrpPro: 0.518 ± 0.006	0.532TrpGln: 0.532 ± 0.007	0.734TrpArg: 0.734 ± 0.007	0.86TrpSer: 0.86 ± 0.008	0.658TrpThr: 0.658 ± 0.007	0.704TrpVal: 0.704 ± 0.007	0.2TrpTrp: 0.2 ± 0.004	0.334TrpTyr: 0.334 ± 0.005	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.424TyrAla: 1.424 ± 0.009	0.677TyrCys: 0.677 ± 0.007	1.322TyrAsp: 1.322 ± 0.01	1.717TyrGlu: 1.717 ± 0.013	1.22TyrPhe: 1.22 ± 0.009	1.691TyrGly: 1.691 ± 0.013	0.758TyrHis: 0.758 ± 0.006	1.364TyrIle: 1.364 ± 0.01	1.507TyrLys: 1.507 ± 0.022	2.64TyrLeu: 2.64 ± 0.011	0.606TyrMet: 0.606 ± 0.006	1.112TyrAsn: 1.112 ± 0.009	1.292TyrPro: 1.292 ± 0.01	1.253TyrGln: 1.253 ± 0.008	1.643TyrArg: 1.643 ± 0.013	2.19TyrSer: 2.19 ± 0.013	1.441TyrThr: 1.441 ± 0.011	1.606TyrVal: 1.606 ± 0.012	0.365TyrTrp: 0.365 ± 0.006	0.957TyrTyr: 0.957 ± 0.009	0.001TyrXaa: 0.001 ± 0.0
Xaa	0.001XaaAla: 0.001 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.001XaaAsp: 0.001 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.001XaaGly: 0.001 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.001XaaAsn: 0.001 ± 0.0	0.001XaaPro: 0.001 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.001XaaSer: 0.001 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.001XaaVal: 0.001 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.236XaaXaa: 0.236 ± 0.043

Statistics based on 32115 proteins (17273278 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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