Amino acid dipepetide frequency for Halovirus HRTV-7

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.991AlaAla: 7.991 ± 0.897
0.585AlaCys: 0.585 ± 0.198
6.188AlaAsp: 6.188 ± 0.658
10.184AlaGlu: 10.184 ± 0.852
2.631AlaPhe: 2.631 ± 0.335
4.97AlaGly: 4.97 ± 0.542
1.413AlaHis: 1.413 ± 0.269
4.386AlaIle: 4.386 ± 0.454
2.68AlaLys: 2.68 ± 0.364
6.042AlaLeu: 6.042 ± 0.486
2.339AlaMet: 2.339 ± 0.299
2.729AlaAsn: 2.729 ± 0.338
2.875AlaPro: 2.875 ± 0.495
2.485AlaGln: 2.485 ± 0.387
4.58AlaArg: 4.58 ± 0.448
4.288AlaSer: 4.288 ± 0.477
4.483AlaThr: 4.483 ± 0.452
5.945AlaVal: 5.945 ± 0.553
0.78AlaTrp: 0.78 ± 0.207
2.29AlaTyr: 2.29 ± 0.331
0.0AlaXaa: 0.0 ± 0.0
Cys
0.439CysAla: 0.439 ± 0.141
0.195CysCys: 0.195 ± 0.11
0.731CysAsp: 0.731 ± 0.222
0.828CysGlu: 0.828 ± 0.233
0.195CysPhe: 0.195 ± 0.109
0.975CysGly: 0.975 ± 0.218
0.244CysHis: 0.244 ± 0.12
0.439CysIle: 0.439 ± 0.137
0.146CysLys: 0.146 ± 0.079
0.39CysLeu: 0.39 ± 0.143
0.195CysMet: 0.195 ± 0.102
0.292CysAsn: 0.292 ± 0.122
0.78CysPro: 0.78 ± 0.231
0.244CysGln: 0.244 ± 0.107
0.341CysArg: 0.341 ± 0.129
0.244CysSer: 0.244 ± 0.137
0.195CysThr: 0.195 ± 0.101
0.341CysVal: 0.341 ± 0.13
0.049CysTrp: 0.049 ± 0.053
0.292CysTyr: 0.292 ± 0.11
0.0CysXaa: 0.0 ± 0.0
Asp
7.991AspAla: 7.991 ± 0.787
0.341AspCys: 0.341 ± 0.149
9.112AspAsp: 9.112 ± 0.803
9.502AspGlu: 9.502 ± 0.694
4.093AspPhe: 4.093 ± 0.476
8.527AspGly: 8.527 ± 0.741
1.559AspHis: 1.559 ± 0.273
3.947AspIle: 3.947 ± 0.414
2.241AspLys: 2.241 ± 0.314
6.822AspLeu: 6.822 ± 0.498
1.316AspMet: 1.316 ± 0.257
3.119AspAsn: 3.119 ± 0.422
4.142AspPro: 4.142 ± 0.476
1.559AspGln: 1.559 ± 0.281
5.019AspArg: 5.019 ± 0.536
5.165AspSer: 5.165 ± 0.599
3.752AspThr: 3.752 ± 0.468
4.97AspVal: 4.97 ± 0.46
1.852AspTrp: 1.852 ± 0.291
3.752AspTyr: 3.752 ± 0.418
0.0AspXaa: 0.0 ± 0.0
Glu
9.258GluAla: 9.258 ± 0.891
0.78GluCys: 0.78 ± 0.202
8.576GluAsp: 8.576 ± 0.77
7.602GluGlu: 7.602 ± 0.652
3.947GluPhe: 3.947 ± 0.549
7.163GluGly: 7.163 ± 0.579
1.9GluHis: 1.9 ± 0.321
4.58GluIle: 4.58 ± 0.466
3.119GluLys: 3.119 ± 0.358
7.845GluLeu: 7.845 ± 0.432
3.557GluMet: 3.557 ± 0.491
4.044GluAsn: 4.044 ± 0.53
4.483GluPro: 4.483 ± 0.434
4.191GluGln: 4.191 ± 0.504
5.75GluArg: 5.75 ± 0.584
4.239GluSer: 4.239 ± 0.476
5.36GluThr: 5.36 ± 0.58
8.04GluVal: 8.04 ± 0.547
1.754GluTrp: 1.754 ± 0.296
2.826GluTyr: 2.826 ± 0.391
0.0GluXaa: 0.0 ± 0.0
Phe
3.021PheAla: 3.021 ± 0.353
0.39PheCys: 0.39 ± 0.144
3.07PheAsp: 3.07 ± 0.368
3.947PheGlu: 3.947 ± 0.505
1.267PhePhe: 1.267 ± 0.233
3.021PheGly: 3.021 ± 0.399
1.364PheHis: 1.364 ± 0.226
1.657PheIle: 1.657 ± 0.307
1.9PheLys: 1.9 ± 0.425
1.803PheLeu: 1.803 ± 0.292
0.585PheMet: 0.585 ± 0.17
1.462PheAsn: 1.462 ± 0.292
1.9PhePro: 1.9 ± 0.357
1.169PheGln: 1.169 ± 0.163
2.144PheArg: 2.144 ± 0.314
1.9PheSer: 1.9 ± 0.356
2.144PheThr: 2.144 ± 0.38
1.949PheVal: 1.949 ± 0.267
0.146PheTrp: 0.146 ± 0.079
1.218PheTyr: 1.218 ± 0.265
0.0PheXaa: 0.0 ± 0.0
Gly
5.506GlyAla: 5.506 ± 0.749
0.487GlyCys: 0.487 ± 0.191
7.017GlyAsp: 7.017 ± 0.734
7.943GlyGlu: 7.943 ± 0.622
3.216GlyPhe: 3.216 ± 0.376
8.674GlyGly: 8.674 ± 2.007
1.998GlyHis: 1.998 ± 0.366
3.655GlyIle: 3.655 ± 0.48
2.972GlyLys: 2.972 ± 0.364
4.678GlyLeu: 4.678 ± 0.489
2.144GlyMet: 2.144 ± 0.312
3.119GlyAsn: 3.119 ± 0.412
2.241GlyPro: 2.241 ± 0.331
2.388GlyGln: 2.388 ± 0.37
3.801GlyArg: 3.801 ± 0.447
4.824GlySer: 4.824 ± 0.806
3.411GlyThr: 3.411 ± 0.369
5.263GlyVal: 5.263 ± 0.518
1.267GlyTrp: 1.267 ± 0.262
2.972GlyTyr: 2.972 ± 0.316
0.0GlyXaa: 0.0 ± 0.0
His
1.511HisAla: 1.511 ± 0.293
0.097HisCys: 0.097 ± 0.072
1.754HisAsp: 1.754 ± 0.31
2.339HisGlu: 2.339 ± 0.423
0.585HisPhe: 0.585 ± 0.184
1.803HisGly: 1.803 ± 0.365
0.536HisHis: 0.536 ± 0.172
1.364HisIle: 1.364 ± 0.286
0.78HisLys: 0.78 ± 0.263
1.803HisLeu: 1.803 ± 0.333
0.341HisMet: 0.341 ± 0.116
1.121HisAsn: 1.121 ± 0.257
1.9HisPro: 1.9 ± 0.276
0.585HisGln: 0.585 ± 0.155
1.754HisArg: 1.754 ± 0.346
0.975HisSer: 0.975 ± 0.232
0.926HisThr: 0.926 ± 0.19
1.754HisVal: 1.754 ± 0.293
0.244HisTrp: 0.244 ± 0.12
0.926HisTyr: 0.926 ± 0.204
0.0HisXaa: 0.0 ± 0.0
Ile
3.46IleAla: 3.46 ± 0.489
0.39IleCys: 0.39 ± 0.145
4.824IleAsp: 4.824 ± 0.478
6.042IleGlu: 6.042 ± 0.629
1.023IlePhe: 1.023 ± 0.225
2.924IleGly: 2.924 ± 0.348
0.731IleHis: 0.731 ± 0.189
2.144IleIle: 2.144 ± 0.373
1.413IleLys: 1.413 ± 0.294
3.119IleLeu: 3.119 ± 0.428
0.731IleMet: 0.731 ± 0.174
1.803IleAsn: 1.803 ± 0.342
2.339IlePro: 2.339 ± 0.348
1.511IleGln: 1.511 ± 0.27
2.875IleArg: 2.875 ± 0.414
3.167IleSer: 3.167 ± 0.436
3.167IleThr: 3.167 ± 0.386
2.534IleVal: 2.534 ± 0.323
0.292IleTrp: 0.292 ± 0.105
1.169IleTyr: 1.169 ± 0.237
0.0IleXaa: 0.0 ± 0.0
Lys
3.021LysAla: 3.021 ± 0.496
0.39LysCys: 0.39 ± 0.188
2.972LysAsp: 2.972 ± 0.376
2.778LysGlu: 2.778 ± 0.437
1.608LysPhe: 1.608 ± 0.321
1.608LysGly: 1.608 ± 0.234
0.926LysHis: 0.926 ± 0.24
0.975LysIle: 0.975 ± 0.239
1.657LysLys: 1.657 ± 0.467
1.998LysLeu: 1.998 ± 0.344
1.413LysMet: 1.413 ± 0.224
1.803LysAsn: 1.803 ± 0.327
2.241LysPro: 2.241 ± 0.27
1.462LysGln: 1.462 ± 0.279
2.778LysArg: 2.778 ± 0.405
2.631LysSer: 2.631 ± 0.416
2.095LysThr: 2.095 ± 0.304
2.485LysVal: 2.485 ± 0.349
0.682LysTrp: 0.682 ± 0.165
1.316LysTyr: 1.316 ± 0.288
0.0LysXaa: 0.0 ± 0.0
Leu
4.922LeuAla: 4.922 ± 0.414
0.78LeuCys: 0.78 ± 0.179
6.822LeuAsp: 6.822 ± 0.654
5.994LeuGlu: 5.994 ± 0.55
2.144LeuPhe: 2.144 ± 0.361
4.532LeuGly: 4.532 ± 0.702
2.095LeuHis: 2.095 ± 0.339
3.265LeuIle: 3.265 ± 0.436
2.972LeuLys: 2.972 ± 0.448
4.922LeuLeu: 4.922 ± 0.507
1.657LeuMet: 1.657 ± 0.206
2.826LeuAsn: 2.826 ± 0.372
3.167LeuPro: 3.167 ± 0.354
1.705LeuGln: 1.705 ± 0.261
5.311LeuArg: 5.311 ± 0.589
3.996LeuSer: 3.996 ± 0.481
4.191LeuThr: 4.191 ± 0.493
4.775LeuVal: 4.775 ± 0.48
1.072LeuTrp: 1.072 ± 0.225
1.803LeuTyr: 1.803 ± 0.226
0.0LeuXaa: 0.0 ± 0.0
Met
1.852MetAla: 1.852 ± 0.369
0.049MetCys: 0.049 ± 0.051
1.754MetAsp: 1.754 ± 0.384
2.095MetGlu: 2.095 ± 0.298
0.536MetPhe: 0.536 ± 0.156
1.608MetGly: 1.608 ± 0.243
0.439MetHis: 0.439 ± 0.155
0.487MetIle: 0.487 ± 0.169
1.267MetLys: 1.267 ± 0.262
1.608MetLeu: 1.608 ± 0.261
0.439MetMet: 0.439 ± 0.144
1.413MetAsn: 1.413 ± 0.292
1.608MetPro: 1.608 ± 0.256
0.39MetGln: 0.39 ± 0.121
1.267MetArg: 1.267 ± 0.262
2.29MetSer: 2.29 ± 0.346
2.193MetThr: 2.193 ± 0.267
1.803MetVal: 1.803 ± 0.303
0.487MetTrp: 0.487 ± 0.153
0.585MetTyr: 0.585 ± 0.168
0.0MetXaa: 0.0 ± 0.0
Asn
3.167AsnAla: 3.167 ± 0.406
0.244AsnCys: 0.244 ± 0.098
3.411AsnAsp: 3.411 ± 0.473
2.972AsnGlu: 2.972 ± 0.37
1.511AsnPhe: 1.511 ± 0.272
3.411AsnGly: 3.411 ± 0.475
1.023AsnHis: 1.023 ± 0.231
2.193AsnIle: 2.193 ± 0.386
1.267AsnLys: 1.267 ± 0.252
2.144AsnLeu: 2.144 ± 0.303
1.023AsnMet: 1.023 ± 0.24
1.803AsnAsn: 1.803 ± 0.443
2.534AsnPro: 2.534 ± 0.301
1.072AsnGln: 1.072 ± 0.258
2.631AsnArg: 2.631 ± 0.389
2.047AsnSer: 2.047 ± 0.277
2.29AsnThr: 2.29 ± 0.428
2.241AsnVal: 2.241 ± 0.373
0.487AsnTrp: 0.487 ± 0.145
1.657AsnTyr: 1.657 ± 0.378
0.0AsnXaa: 0.0 ± 0.0
Pro
3.119ProAla: 3.119 ± 0.408
0.097ProCys: 0.097 ± 0.067
6.383ProAsp: 6.383 ± 0.59
5.701ProGlu: 5.701 ± 0.513
1.803ProPhe: 1.803 ± 0.353
3.655ProGly: 3.655 ± 0.357
1.218ProHis: 1.218 ± 0.254
2.241ProIle: 2.241 ± 0.263
1.608ProLys: 1.608 ± 0.279
2.388ProLeu: 2.388 ± 0.406
1.608ProMet: 1.608 ± 0.254
2.095ProAsn: 2.095 ± 0.295
2.388ProPro: 2.388 ± 0.333
1.413ProGln: 1.413 ± 0.241
2.583ProArg: 2.583 ± 0.363
2.339ProSer: 2.339 ± 0.367
2.826ProThr: 2.826 ± 0.477
3.314ProVal: 3.314 ± 0.41
0.585ProTrp: 0.585 ± 0.215
1.023ProTyr: 1.023 ± 0.226
0.0ProXaa: 0.0 ± 0.0
Gln
2.436GlnAla: 2.436 ± 0.273
0.195GlnCys: 0.195 ± 0.119
1.462GlnAsp: 1.462 ± 0.268
2.972GlnGlu: 2.972 ± 0.349
1.267GlnPhe: 1.267 ± 0.224
1.803GlnGly: 1.803 ± 0.289
0.731GlnHis: 0.731 ± 0.21
1.413GlnIle: 1.413 ± 0.248
1.608GlnLys: 1.608 ± 0.283
1.803GlnLeu: 1.803 ± 0.291
0.828GlnMet: 0.828 ± 0.224
1.072GlnAsn: 1.072 ± 0.275
1.608GlnPro: 1.608 ± 0.266
1.559GlnGln: 1.559 ± 0.27
2.241GlnArg: 2.241 ± 0.351
1.754GlnSer: 1.754 ± 0.295
1.803GlnThr: 1.803 ± 0.345
2.485GlnVal: 2.485 ± 0.354
0.487GlnTrp: 0.487 ± 0.167
1.169GlnTyr: 1.169 ± 0.236
0.0GlnXaa: 0.0 ± 0.0
Arg
4.873ArgAla: 4.873 ± 0.528
0.487ArgCys: 0.487 ± 0.144
4.58ArgAsp: 4.58 ± 0.404
5.555ArgGlu: 5.555 ± 0.53
2.29ArgPhe: 2.29 ± 0.305
3.898ArgGly: 3.898 ± 0.401
1.754ArgHis: 1.754 ± 0.349
2.826ArgIle: 2.826 ± 0.4
2.29ArgLys: 2.29 ± 0.393
4.97ArgLeu: 4.97 ± 0.476
1.316ArgMet: 1.316 ± 0.24
2.193ArgAsn: 2.193 ± 0.307
2.29ArgPro: 2.29 ± 0.355
2.193ArgGln: 2.193 ± 0.34
5.847ArgArg: 5.847 ± 0.746
3.85ArgSer: 3.85 ± 0.457
3.703ArgThr: 3.703 ± 0.405
4.239ArgVal: 4.239 ± 0.416
0.926ArgTrp: 0.926 ± 0.218
2.485ArgTyr: 2.485 ± 0.347
0.0ArgXaa: 0.0 ± 0.0
Ser
4.191SerAla: 4.191 ± 0.435
0.536SerCys: 0.536 ± 0.188
4.288SerAsp: 4.288 ± 0.497
6.53SerGlu: 6.53 ± 0.667
1.852SerPhe: 1.852 ± 0.329
5.263SerGly: 5.263 ± 0.825
1.072SerHis: 1.072 ± 0.248
2.778SerIle: 2.778 ± 0.375
2.631SerLys: 2.631 ± 0.35
4.386SerLeu: 4.386 ± 0.493
1.023SerMet: 1.023 ± 0.2
1.803SerAsn: 1.803 ± 0.384
3.362SerPro: 3.362 ± 0.332
1.9SerGln: 1.9 ± 0.346
3.606SerArg: 3.606 ± 0.399
3.265SerSer: 3.265 ± 0.438
2.68SerThr: 2.68 ± 0.361
3.752SerVal: 3.752 ± 0.525
1.169SerTrp: 1.169 ± 0.219
1.511SerTyr: 1.511 ± 0.256
0.0SerXaa: 0.0 ± 0.0
Thr
4.434ThrAla: 4.434 ± 0.465
0.439ThrCys: 0.439 ± 0.137
4.288ThrAsp: 4.288 ± 0.466
4.922ThrGlu: 4.922 ± 0.618
2.095ThrPhe: 2.095 ± 0.335
4.97ThrGly: 4.97 ± 0.492
1.462ThrHis: 1.462 ± 0.278
2.778ThrIle: 2.778 ± 0.349
2.144ThrLys: 2.144 ± 0.39
4.434ThrLeu: 4.434 ± 0.427
1.608ThrMet: 1.608 ± 0.315
1.511ThrAsn: 1.511 ± 0.272
3.314ThrPro: 3.314 ± 0.467
1.608ThrGln: 1.608 ± 0.309
3.411ThrArg: 3.411 ± 0.343
2.875ThrSer: 2.875 ± 0.403
3.85ThrThr: 3.85 ± 0.468
4.386ThrVal: 4.386 ± 0.498
0.536ThrTrp: 0.536 ± 0.146
1.949ThrTyr: 1.949 ± 0.335
0.0ThrXaa: 0.0 ± 0.0
Val
5.701ValAla: 5.701 ± 0.559
0.536ValCys: 0.536 ± 0.166
6.335ValAsp: 6.335 ± 0.579
6.724ValGlu: 6.724 ± 0.61
2.388ValPhe: 2.388 ± 0.386
5.165ValGly: 5.165 ± 0.515
1.657ValHis: 1.657 ± 0.292
2.631ValIle: 2.631 ± 0.299
2.339ValLys: 2.339 ± 0.374
4.58ValLeu: 4.58 ± 0.444
1.218ValMet: 1.218 ± 0.211
2.631ValAsn: 2.631 ± 0.385
3.167ValPro: 3.167 ± 0.355
2.144ValGln: 2.144 ± 0.359
4.044ValArg: 4.044 ± 0.526
4.386ValSer: 4.386 ± 0.432
4.824ValThr: 4.824 ± 0.501
5.847ValVal: 5.847 ± 0.514
0.536ValTrp: 0.536 ± 0.151
2.534ValTyr: 2.534 ± 0.382
0.0ValXaa: 0.0 ± 0.0
Trp
0.78TrpAla: 0.78 ± 0.2
0.146TrpCys: 0.146 ± 0.074
1.169TrpAsp: 1.169 ± 0.249
1.072TrpGlu: 1.072 ± 0.249
0.828TrpPhe: 0.828 ± 0.196
1.023TrpGly: 1.023 ± 0.193
0.244TrpHis: 0.244 ± 0.112
0.39TrpIle: 0.39 ± 0.122
0.78TrpLys: 0.78 ± 0.191
1.316TrpLeu: 1.316 ± 0.275
0.487TrpMet: 0.487 ± 0.156
0.828TrpAsn: 0.828 ± 0.212
0.341TrpPro: 0.341 ± 0.124
0.244TrpGln: 0.244 ± 0.112
0.633TrpArg: 0.633 ± 0.157
1.023TrpSer: 1.023 ± 0.216
1.072TrpThr: 1.072 ± 0.234
1.218TrpVal: 1.218 ± 0.246
0.244TrpTrp: 0.244 ± 0.116
0.487TrpTyr: 0.487 ± 0.153
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.193TyrAla: 2.193 ± 0.342
0.39TyrCys: 0.39 ± 0.148
4.044TyrAsp: 4.044 ± 0.527
3.314TyrGlu: 3.314 ± 0.413
0.78TyrPhe: 0.78 ± 0.196
2.583TyrGly: 2.583 ± 0.376
0.731TyrHis: 0.731 ± 0.201
1.511TyrIle: 1.511 ± 0.282
1.023TyrLys: 1.023 ± 0.183
1.949TyrLeu: 1.949 ± 0.326
0.292TyrMet: 0.292 ± 0.112
1.462TyrAsn: 1.462 ± 0.271
1.705TyrPro: 1.705 ± 0.339
0.877TyrGln: 0.877 ± 0.208
1.949TyrArg: 1.949 ± 0.32
2.339TyrSer: 2.339 ± 0.373
2.047TyrThr: 2.047 ± 0.348
2.047TyrVal: 2.047 ± 0.294
0.731TyrTrp: 0.731 ± 0.199
1.364TyrTyr: 1.364 ± 0.233
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 105 proteins (20523 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski