Amino acid dipepetide frequency for Canarypox virus (CNPV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.739AlaAla: 1.739 ± 0.145
0.907AlaCys: 0.907 ± 0.095
2.767AlaAsp: 2.767 ± 0.202
1.748AlaGlu: 1.748 ± 0.155
1.019AlaPhe: 1.019 ± 0.112
1.346AlaGly: 1.346 ± 0.158
0.374AlaHis: 0.374 ± 0.059
3.955AlaIle: 3.955 ± 0.208
2.515AlaLys: 2.515 ± 0.181
2.926AlaLeu: 2.926 ± 0.163
1.028AlaMet: 1.028 ± 0.192
2.365AlaAsn: 2.365 ± 0.168
0.729AlaPro: 0.729 ± 0.086
0.467AlaGln: 0.467 ± 0.06
1.374AlaArg: 1.374 ± 0.127
2.73AlaSer: 2.73 ± 0.176
1.889AlaThr: 1.889 ± 0.148
3.244AlaVal: 3.244 ± 0.213
0.15AlaTrp: 0.15 ± 0.04
1.58AlaTyr: 1.58 ± 0.125
0.0AlaXaa: 0.0 ± 0.0
Cys
0.626CysAla: 0.626 ± 0.078
0.608CysCys: 0.608 ± 0.108
1.262CysAsp: 1.262 ± 0.117
1.084CysGlu: 1.084 ± 0.101
1.019CysPhe: 1.019 ± 0.09
1.094CysGly: 1.094 ± 0.11
0.393CysHis: 0.393 ± 0.064
2.459CysIle: 2.459 ± 0.172
1.926CysLys: 1.926 ± 0.143
1.58CysLeu: 1.58 ± 0.118
0.645CysMet: 0.645 ± 0.07
1.982CysAsn: 1.982 ± 0.142
0.654CysPro: 0.654 ± 0.098
0.29CysGln: 0.29 ± 0.062
0.823CysArg: 0.823 ± 0.101
1.673CysSer: 1.673 ± 0.148
0.972CysThr: 0.972 ± 0.1
1.356CysVal: 1.356 ± 0.156
0.224CysTrp: 0.224 ± 0.045
1.627CysTyr: 1.627 ± 0.145
0.0CysXaa: 0.0 ± 0.0
Asp
2.019AspAla: 2.019 ± 0.138
1.028AspCys: 1.028 ± 0.1
4.347AspAsp: 4.347 ± 0.31
3.487AspGlu: 3.487 ± 0.186
2.777AspPhe: 2.777 ± 0.154
2.094AspGly: 2.094 ± 0.149
0.879AspHis: 0.879 ± 0.085
7.591AspIle: 7.591 ± 0.313
5.609AspLys: 5.609 ± 0.219
4.955AspLeu: 4.955 ± 0.253
1.645AspMet: 1.645 ± 0.112
5.17AspAsn: 5.17 ± 0.28
1.795AspPro: 1.795 ± 0.134
1.075AspGln: 1.075 ± 0.103
2.506AspArg: 2.506 ± 0.16
4.721AspSer: 4.721 ± 0.272
4.431AspThr: 4.431 ± 0.215
4.366AspVal: 4.366 ± 0.239
0.393AspTrp: 0.393 ± 0.057
3.497AspTyr: 3.497 ± 0.164
0.0AspXaa: 0.0 ± 0.0
Glu
1.655GluAla: 1.655 ± 0.138
1.234GluCys: 1.234 ± 0.1
3.936GluAsp: 3.936 ± 0.243
4.179GluGlu: 4.179 ± 0.251
2.291GluPhe: 2.291 ± 0.134
1.991GluGly: 1.991 ± 0.138
1.056GluHis: 1.056 ± 0.115
5.759GluIle: 5.759 ± 0.49
4.852GluLys: 4.852 ± 0.196
6.722GluLeu: 6.722 ± 0.377
1.412GluMet: 1.412 ± 0.163
3.945GluAsn: 3.945 ± 0.246
1.234GluPro: 1.234 ± 0.144
1.337GluGln: 1.337 ± 0.107
2.898GluArg: 2.898 ± 0.38
3.842GluSer: 3.842 ± 0.219
3.272GluThr: 3.272 ± 0.249
3.45GluVal: 3.45 ± 0.196
0.374GluTrp: 0.374 ± 0.062
3.824GluTyr: 3.824 ± 0.198
0.0GluXaa: 0.0 ± 0.0
Phe
1.122PheAla: 1.122 ± 0.106
0.888PheCys: 0.888 ± 0.099
2.057PheAsp: 2.057 ± 0.134
1.907PheGlu: 1.907 ± 0.133
1.748PhePhe: 1.748 ± 0.165
1.43PheGly: 1.43 ± 0.124
0.795PheHis: 0.795 ± 0.077
4.029PheIle: 4.029 ± 0.213
3.328PheLys: 3.328 ± 0.166
3.637PheLeu: 3.637 ± 0.222
1.066PheMet: 1.066 ± 0.103
3.282PheAsn: 3.282 ± 0.221
1.337PhePro: 1.337 ± 0.093
0.673PheGln: 0.673 ± 0.09
1.43PheArg: 1.43 ± 0.125
3.394PheSer: 3.394 ± 0.251
2.823PheThr: 2.823 ± 0.173
2.272PheVal: 2.272 ± 0.141
0.28PheTrp: 0.28 ± 0.053
2.085PheTyr: 2.085 ± 0.134
0.0PheXaa: 0.0 ± 0.0
Gly
2.833GlyAla: 2.833 ± 0.224
0.916GlyCys: 0.916 ± 0.089
2.244GlyAsp: 2.244 ± 0.202
1.702GlyGlu: 1.702 ± 0.152
1.608GlyPhe: 1.608 ± 0.119
1.655GlyGly: 1.655 ± 0.249
0.636GlyHis: 0.636 ± 0.092
3.543GlyIle: 3.543 ± 0.177
3.646GlyLys: 3.646 ± 0.185
2.59GlyLeu: 2.59 ± 0.165
0.869GlyMet: 0.869 ± 0.087
3.253GlyAsn: 3.253 ± 0.318
0.711GlyPro: 0.711 ± 0.091
0.57GlyGln: 0.57 ± 0.071
1.72GlyArg: 1.72 ± 0.15
3.113GlySer: 3.113 ± 0.395
1.702GlyThr: 1.702 ± 0.139
2.132GlyVal: 2.132 ± 0.156
0.262GlyTrp: 0.262 ± 0.076
2.767GlyTyr: 2.767 ± 0.164
0.0GlyXaa: 0.0 ± 0.0
His
0.748HisAla: 0.748 ± 0.092
0.439HisCys: 0.439 ± 0.063
1.028HisAsp: 1.028 ± 0.084
1.028HisGlu: 1.028 ± 0.096
0.729HisPhe: 0.729 ± 0.073
1.141HisGly: 1.141 ± 0.118
0.552HisHis: 0.552 ± 0.083
2.113HisIle: 2.113 ± 0.153
1.3HisLys: 1.3 ± 0.125
1.561HisLeu: 1.561 ± 0.12
0.486HisMet: 0.486 ± 0.074
1.711HisAsn: 1.711 ± 0.145
0.682HisPro: 0.682 ± 0.084
0.542HisGln: 0.542 ± 0.08
0.944HisArg: 0.944 ± 0.093
1.356HisSer: 1.356 ± 0.116
0.86HisThr: 0.86 ± 0.094
1.131HisVal: 1.131 ± 0.107
0.168HisTrp: 0.168 ± 0.038
1.3HisTyr: 1.3 ± 0.133
0.0HisXaa: 0.0 ± 0.0
Ile
3.665IleAla: 3.665 ± 0.201
2.038IleCys: 2.038 ± 0.165
6.787IleAsp: 6.787 ± 0.306
5.965IleGlu: 5.965 ± 0.323
3.291IlePhe: 3.291 ± 0.204
2.917IleGly: 2.917 ± 0.141
1.973IleHis: 1.973 ± 0.14
8.452IleIle: 8.452 ± 0.362
8.246IleLys: 8.246 ± 0.367
8.741IleLeu: 8.741 ± 0.309
2.356IleMet: 2.356 ± 0.167
8.676IleAsn: 8.676 ± 0.379
3.104IlePro: 3.104 ± 0.166
2.076IleGln: 2.076 ± 0.199
4.076IleArg: 4.076 ± 0.206
8.04IleSer: 8.04 ± 0.275
5.993IleThr: 5.993 ± 0.255
5.086IleVal: 5.086 ± 0.215
0.505IleTrp: 0.505 ± 0.072
4.46IleTyr: 4.46 ± 0.228
0.0IleXaa: 0.0 ± 0.0
Lys
2.506LysAla: 2.506 ± 0.184
1.907LysCys: 1.907 ± 0.143
5.965LysAsp: 5.965 ± 0.23
6.264LysGlu: 6.264 ± 0.372
2.992LysPhe: 2.992 ± 0.175
3.029LysGly: 3.029 ± 0.173
1.991LysHis: 1.991 ± 0.132
7.638LysIle: 7.638 ± 0.371
7.433LysLys: 7.433 ± 0.29
7.825LysLeu: 7.825 ± 0.463
1.889LysMet: 1.889 ± 0.142
6.021LysAsn: 6.021 ± 0.301
1.851LysPro: 1.851 ± 0.147
2.104LysGln: 2.104 ± 0.148
3.693LysArg: 3.693 ± 0.221
5.236LysSer: 5.236 ± 0.194
4.329LysThr: 4.329 ± 0.198
4.609LysVal: 4.609 ± 0.239
0.542LysTrp: 0.542 ± 0.065
5.965LysTyr: 5.965 ± 0.289
0.0LysXaa: 0.0 ± 0.0
Leu
2.636LeuAla: 2.636 ± 0.156
2.15LeuCys: 2.15 ± 0.157
5.909LeuAsp: 5.909 ± 0.254
6.161LeuGlu: 6.161 ± 0.275
3.656LeuPhe: 3.656 ± 0.23
3.394LeuGly: 3.394 ± 0.199
3.076LeuHis: 3.076 ± 0.284
7.909LeuIle: 7.909 ± 0.311
7.227LeuLys: 7.227 ± 0.39
11.696LeuLeu: 11.696 ± 0.595
2.384LeuMet: 2.384 ± 0.149
4.647LeuAsn: 4.647 ± 0.208
3.141LeuPro: 3.141 ± 0.288
2.132LeuGln: 2.132 ± 0.135
3.571LeuArg: 3.571 ± 0.174
7.797LeuSer: 7.797 ± 0.316
4.216LeuThr: 4.216 ± 0.254
4.992LeuVal: 4.992 ± 0.246
0.393LeuTrp: 0.393 ± 0.068
4.946LeuTyr: 4.946 ± 0.224
0.0LeuXaa: 0.0 ± 0.0
Met
0.935MetAla: 0.935 ± 0.112
0.57MetCys: 0.57 ± 0.075
1.795MetAsp: 1.795 ± 0.155
1.954MetGlu: 1.954 ± 0.142
1.3MetPhe: 1.3 ± 0.103
0.823MetGly: 0.823 ± 0.082
0.458MetHis: 0.458 ± 0.066
2.253MetIle: 2.253 ± 0.143
2.281MetLys: 2.281 ± 0.136
2.337MetLeu: 2.337 ± 0.156
0.823MetMet: 0.823 ± 0.082
1.711MetAsn: 1.711 ± 0.108
0.757MetPro: 0.757 ± 0.093
0.729MetGln: 0.729 ± 0.324
0.804MetArg: 0.804 ± 0.096
1.917MetSer: 1.917 ± 0.161
1.066MetThr: 1.066 ± 0.113
1.412MetVal: 1.412 ± 0.108
0.14MetTrp: 0.14 ± 0.037
1.645MetTyr: 1.645 ± 0.137
0.0MetXaa: 0.0 ± 0.0
Asn
2.87AsnAla: 2.87 ± 0.19
1.421AsnCys: 1.421 ± 0.136
4.488AsnAsp: 4.488 ± 0.172
3.73AsnGlu: 3.73 ± 0.164
2.739AsnPhe: 2.739 ± 0.166
3.515AsnGly: 3.515 ± 0.201
1.234AsnHis: 1.234 ± 0.114
8.76AsnIle: 8.76 ± 0.363
6.488AsnLys: 6.488 ± 0.343
5.236AsnLeu: 5.236 ± 0.215
2.001AsnMet: 2.001 ± 0.149
7.087AsnAsn: 7.087 ± 0.397
2.066AsnPro: 2.066 ± 0.131
1.122AsnGln: 1.122 ± 0.108
3.141AsnArg: 3.141 ± 0.158
6.142AsnSer: 6.142 ± 0.316
5.179AsnThr: 5.179 ± 0.243
4.413AsnVal: 4.413 ± 0.219
0.486AsnTrp: 0.486 ± 0.061
4.142AsnTyr: 4.142 ± 0.205
0.0AsnXaa: 0.0 ± 0.0
Pro
0.72ProAla: 0.72 ± 0.095
0.729ProCys: 0.729 ± 0.083
2.104ProAsp: 2.104 ± 0.148
1.776ProGlu: 1.776 ± 0.15
1.309ProPhe: 1.309 ± 0.116
1.113ProGly: 1.113 ± 0.136
0.617ProHis: 0.617 ± 0.081
2.749ProIle: 2.749 ± 0.157
1.879ProLys: 1.879 ± 0.167
3.712ProLeu: 3.712 ± 0.282
0.57ProMet: 0.57 ± 0.081
2.234ProAsn: 2.234 ± 0.119
0.991ProPro: 0.991 ± 0.146
0.496ProGln: 0.496 ± 0.085
1.01ProArg: 1.01 ± 0.118
2.375ProSer: 2.375 ± 0.184
1.356ProThr: 1.356 ± 0.188
1.86ProVal: 1.86 ± 0.216
0.234ProTrp: 0.234 ± 0.039
1.468ProTyr: 1.468 ± 0.126
0.0ProXaa: 0.0 ± 0.0
Gln
0.767GlnAla: 0.767 ± 0.064
0.365GlnCys: 0.365 ± 0.058
1.384GlnAsp: 1.384 ± 0.122
1.73GlnGlu: 1.73 ± 0.445
0.57GlnPhe: 0.57 ± 0.082
0.813GlnGly: 0.813 ± 0.097
0.496GlnHis: 0.496 ± 0.064
1.262GlnIle: 1.262 ± 0.102
1.402GlnLys: 1.402 ± 0.135
2.057GlnLeu: 2.057 ± 0.131
0.477GlnMet: 0.477 ± 0.064
1.374GlnAsn: 1.374 ± 0.118
0.449GlnPro: 0.449 ± 0.096
0.692GlnGln: 0.692 ± 0.096
0.72GlnArg: 0.72 ± 0.083
1.561GlnSer: 1.561 ± 0.172
0.701GlnThr: 0.701 ± 0.096
0.991GlnVal: 0.991 ± 0.101
0.122GlnTrp: 0.122 ± 0.039
1.271GlnTyr: 1.271 ± 0.106
0.0GlnXaa: 0.0 ± 0.0
Arg
1.262ArgAla: 1.262 ± 0.198
0.935ArgCys: 0.935 ± 0.098
2.664ArgAsp: 2.664 ± 0.182
2.459ArgGlu: 2.459 ± 0.236
1.692ArgPhe: 1.692 ± 0.134
1.664ArgGly: 1.664 ± 0.131
0.898ArgHis: 0.898 ± 0.092
3.244ArgIle: 3.244 ± 0.202
3.338ArgLys: 3.338 ± 0.171
3.964ArgLeu: 3.964 ± 0.221
1.215ArgMet: 1.215 ± 0.106
3.197ArgAsn: 3.197 ± 0.203
1.01ArgPro: 1.01 ± 0.124
0.944ArgGln: 0.944 ± 0.123
1.982ArgArg: 1.982 ± 0.187
3.141ArgSer: 3.141 ± 0.236
2.057ArgThr: 2.057 ± 0.174
2.328ArgVal: 2.328 ± 0.16
0.43ArgTrp: 0.43 ± 0.07
2.945ArgTyr: 2.945 ± 0.193
0.0ArgXaa: 0.0 ± 0.0
Ser
2.328SerAla: 2.328 ± 0.183
1.645SerCys: 1.645 ± 0.11
4.581SerAsp: 4.581 ± 0.187
4.244SerGlu: 4.244 ± 0.329
3.515SerPhe: 3.515 ± 0.185
3.833SerGly: 3.833 ± 0.542
1.328SerHis: 1.328 ± 0.123
7.788SerIle: 7.788 ± 0.289
6.844SerLys: 6.844 ± 0.256
6.694SerLeu: 6.694 ± 0.292
1.982SerMet: 1.982 ± 0.142
5.796SerAsn: 5.796 ± 0.24
2.459SerPro: 2.459 ± 0.152
1.3SerGln: 1.3 ± 0.127
3.253SerArg: 3.253 ± 0.255
6.787SerSer: 6.787 ± 0.546
4.104SerThr: 4.104 ± 0.291
5.376SerVal: 5.376 ± 0.284
0.533SerTrp: 0.533 ± 0.074
4.394SerTyr: 4.394 ± 0.225
0.0SerXaa: 0.0 ± 0.0
Thr
2.169ThrAla: 2.169 ± 0.156
1.86ThrCys: 1.86 ± 0.181
3.319ThrAsp: 3.319 ± 0.198
3.394ThrGlu: 3.394 ± 0.231
2.076ThrPhe: 2.076 ± 0.151
1.935ThrGly: 1.935 ± 0.163
0.888ThrHis: 0.888 ± 0.085
5.002ThrIle: 5.002 ± 0.22
3.964ThrLys: 3.964 ± 0.214
5.142ThrLeu: 5.142 ± 0.248
1.449ThrMet: 1.449 ± 0.131
3.403ThrAsn: 3.403 ± 0.166
2.87ThrPro: 2.87 ± 0.271
0.841ThrGln: 0.841 ± 0.093
2.431ThrArg: 2.431 ± 0.147
4.581ThrSer: 4.581 ± 0.315
3.001ThrThr: 3.001 ± 0.267
3.571ThrVal: 3.571 ± 0.243
0.43ThrTrp: 0.43 ± 0.067
2.73ThrTyr: 2.73 ± 0.176
0.0ThrXaa: 0.0 ± 0.0
Val
1.879ValAla: 1.879 ± 0.141
1.346ValCys: 1.346 ± 0.116
3.394ValAsp: 3.394 ± 0.223
3.02ValGlu: 3.02 ± 0.186
2.814ValPhe: 2.814 ± 0.208
1.599ValGly: 1.599 ± 0.148
0.926ValHis: 0.926 ± 0.086
5.89ValIle: 5.89 ± 0.277
6.077ValLys: 6.077 ± 0.355
5.31ValLeu: 5.31 ± 0.237
1.496ValMet: 1.496 ± 0.121
5.226ValAsn: 5.226 ± 0.283
1.73ValPro: 1.73 ± 0.176
0.757ValGln: 0.757 ± 0.075
2.403ValArg: 2.403 ± 0.129
5.684ValSer: 5.684 ± 0.238
3.562ValThr: 3.562 ± 0.181
3.188ValVal: 3.188 ± 0.2
0.327ValTrp: 0.327 ± 0.057
2.945ValTyr: 2.945 ± 0.184
0.0ValXaa: 0.0 ± 0.0
Trp
0.178TrpAla: 0.178 ± 0.058
0.159TrpCys: 0.159 ± 0.041
0.309TrpAsp: 0.309 ± 0.054
0.346TrpGlu: 0.346 ± 0.066
0.28TrpPhe: 0.28 ± 0.051
0.122TrpGly: 0.122 ± 0.035
0.103TrpHis: 0.103 ± 0.027
0.86TrpIle: 0.86 ± 0.1
0.608TrpLys: 0.608 ± 0.086
0.711TrpLeu: 0.711 ± 0.096
0.318TrpMet: 0.318 ± 0.055
0.43TrpAsn: 0.43 ± 0.066
0.159TrpPro: 0.159 ± 0.043
0.122TrpGln: 0.122 ± 0.04
0.252TrpArg: 0.252 ± 0.049
0.411TrpSer: 0.411 ± 0.067
0.383TrpThr: 0.383 ± 0.072
0.421TrpVal: 0.421 ± 0.067
0.112TrpTrp: 0.112 ± 0.052
0.299TrpTyr: 0.299 ± 0.048
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.197TyrAla: 2.197 ± 0.145
1.15TyrCys: 1.15 ± 0.114
4.048TyrAsp: 4.048 ± 0.226
3.085TyrGlu: 3.085 ± 0.176
2.16TyrPhe: 2.16 ± 0.126
2.964TyrGly: 2.964 ± 0.186
1.159TyrHis: 1.159 ± 0.098
5.189TyrIle: 5.189 ± 0.257
4.824TyrLys: 4.824 ± 0.233
4.637TyrLeu: 4.637 ± 0.239
1.589TyrMet: 1.589 ± 0.103
4.749TyrAsn: 4.749 ± 0.234
1.571TyrPro: 1.571 ± 0.138
0.935TyrGln: 0.935 ± 0.092
2.337TyrArg: 2.337 ± 0.138
4.282TyrSer: 4.282 ± 0.217
3.16TyrThr: 3.16 ± 0.189
3.375TyrVal: 3.375 ± 0.192
0.477TyrTrp: 0.477 ± 0.063
3.328TyrTyr: 3.328 ± 0.175
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 322 proteins (106963 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski