Amino acid dipepetide frequency for Chitinophaga ginsengisegetis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.072AlaAla: 9.072 ± 0.09	0.737AlaCys: 0.737 ± 0.016	4.597AlaAsp: 4.597 ± 0.047	4.071AlaGlu: 4.071 ± 0.04	3.569AlaPhe: 3.569 ± 0.041	7.037AlaGly: 7.037 ± 0.073	1.374AlaHis: 1.374 ± 0.021	5.26AlaIle: 5.26 ± 0.046	4.038AlaLys: 4.038 ± 0.047	7.56AlaLeu: 7.56 ± 0.061	1.886AlaMet: 1.886 ± 0.029	3.665AlaAsn: 3.665 ± 0.053	3.093AlaPro: 3.093 ± 0.046	3.155AlaGln: 3.155 ± 0.033	3.16AlaArg: 3.16 ± 0.038	4.659AlaSer: 4.659 ± 0.05	5.211AlaThr: 5.211 ± 0.075	5.626AlaVal: 5.626 ± 0.056	1.052AlaTrp: 1.052 ± 0.023	3.116AlaTyr: 3.116 ± 0.032	0.0AlaXaa: 0.0 ± 0.0
Cys	0.512CysAla: 0.512 ± 0.018	0.136CysCys: 0.136 ± 0.008	0.336CysAsp: 0.336 ± 0.013	0.362CysGlu: 0.362 ± 0.014	0.415CysPhe: 0.415 ± 0.013	0.623CysGly: 0.623 ± 0.018	0.185CysHis: 0.185 ± 0.01	0.595CysIle: 0.595 ± 0.018	0.448CysLys: 0.448 ± 0.016	0.773CysLeu: 0.773 ± 0.017	0.211CysMet: 0.211 ± 0.009	0.399CysAsn: 0.399 ± 0.013	0.29CysPro: 0.29 ± 0.011	0.21CysGln: 0.21 ± 0.01	0.396CysArg: 0.396 ± 0.013	0.504CysSer: 0.504 ± 0.015	0.451CysThr: 0.451 ± 0.015	0.453CysVal: 0.453 ± 0.012	0.119CysTrp: 0.119 ± 0.008	0.356CysTyr: 0.356 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	4.265AspAla: 4.265 ± 0.041	0.333AspCys: 0.333 ± 0.014	2.334AspAsp: 2.334 ± 0.048	2.864AspGlu: 2.864 ± 0.038	2.682AspPhe: 2.682 ± 0.036	3.785AspGly: 3.785 ± 0.054	0.999AspHis: 0.999 ± 0.023	3.894AspIle: 3.894 ± 0.042	3.525AspLys: 3.525 ± 0.038	4.52AspLeu: 4.52 ± 0.041	1.207AspMet: 1.207 ± 0.021	2.788AspAsn: 2.788 ± 0.033	2.318AspPro: 2.318 ± 0.033	1.761AspGln: 1.761 ± 0.028	2.074AspArg: 2.074 ± 0.032	2.95AspSer: 2.95 ± 0.049	2.78AspThr: 2.78 ± 0.038	3.278AspVal: 3.278 ± 0.037	0.789AspTrp: 0.789 ± 0.02	2.426AspTyr: 2.426 ± 0.032	0.0AspXaa: 0.0 ± 0.0
Glu	4.284GluAla: 4.284 ± 0.049	0.319GluCys: 0.319 ± 0.013	2.516GluAsp: 2.516 ± 0.041	3.533GluGlu: 3.533 ± 0.055	2.02GluPhe: 2.02 ± 0.034	3.272GluGly: 3.272 ± 0.044	1.091GluHis: 1.091 ± 0.022	3.766GluIle: 3.766 ± 0.045	4.418GluLys: 4.418 ± 0.056	5.155GluLeu: 5.155 ± 0.066	1.509GluMet: 1.509 ± 0.027	2.878GluAsn: 2.878 ± 0.035	1.62GluPro: 1.62 ± 0.029	2.477GluGln: 2.477 ± 0.036	2.383GluArg: 2.383 ± 0.032	2.539GluSer: 2.539 ± 0.032	2.763GluThr: 2.763 ± 0.036	3.608GluVal: 3.608 ± 0.045	0.703GluTrp: 0.703 ± 0.019	1.945GluTyr: 1.945 ± 0.03	0.0GluXaa: 0.0 ± 0.0
Phe	3.126PheAla: 3.126 ± 0.04	0.412PheCys: 0.412 ± 0.014	2.592PheAsp: 2.592 ± 0.035	2.351PheGlu: 2.351 ± 0.03	2.277PhePhe: 2.277 ± 0.041	3.06PheGly: 3.06 ± 0.038	0.849PheHis: 0.849 ± 0.018	3.03PheIle: 3.03 ± 0.043	2.54PheLys: 2.54 ± 0.034	4.223PheLeu: 4.223 ± 0.051	1.184PheMet: 1.184 ± 0.024	2.794PheAsn: 2.794 ± 0.038	1.905PhePro: 1.905 ± 0.029	1.433PheGln: 1.433 ± 0.028	2.275PheArg: 2.275 ± 0.029	3.573PheSer: 3.573 ± 0.043	3.259PheThr: 3.259 ± 0.042	2.596PheVal: 2.596 ± 0.032	0.568PheTrp: 0.568 ± 0.017	1.998PheTyr: 1.998 ± 0.032	0.0PheXaa: 0.0 ± 0.0
Gly	5.382GlyAla: 5.382 ± 0.057	0.634GlyCys: 0.634 ± 0.02	3.395GlyAsp: 3.395 ± 0.042	3.343GlyGlu: 3.343 ± 0.046	3.486GlyPhe: 3.486 ± 0.042	5.281GlyGly: 5.281 ± 0.083	1.3GlyHis: 1.3 ± 0.022	5.34GlyIle: 5.34 ± 0.047	5.23GlyLys: 5.23 ± 0.062	6.106GlyLeu: 6.106 ± 0.059	1.881GlyMet: 1.881 ± 0.031	4.237GlyAsn: 4.237 ± 0.06	1.864GlyPro: 1.864 ± 0.034	2.465GlyGln: 2.465 ± 0.039	2.906GlyArg: 2.906 ± 0.035	4.514GlySer: 4.514 ± 0.06	4.656GlyThr: 4.656 ± 0.09	4.763GlyVal: 4.763 ± 0.055	1.13GlyTrp: 1.13 ± 0.025	3.393GlyTyr: 3.393 ± 0.047	0.0GlyXaa: 0.0 ± 0.0
His	1.336HisAla: 1.336 ± 0.025	0.196HisCys: 0.196 ± 0.009	0.846HisAsp: 0.846 ± 0.022	0.959HisGlu: 0.959 ± 0.022	1.216HisPhe: 1.216 ± 0.023	1.182HisGly: 1.182 ± 0.024	0.62HisHis: 0.62 ± 0.019	1.405HisIle: 1.405 ± 0.028	0.976HisLys: 0.976 ± 0.02	2.054HisLeu: 2.054 ± 0.036	0.412HisMet: 0.412 ± 0.013	0.913HisAsn: 0.913 ± 0.02	1.177HisPro: 1.177 ± 0.028	0.821HisGln: 0.821 ± 0.017	0.872HisArg: 0.872 ± 0.018	1.04HisSer: 1.04 ± 0.026	1.231HisThr: 1.231 ± 0.025	1.002HisVal: 1.002 ± 0.021	0.283HisTrp: 0.283 ± 0.012	0.95HisTyr: 0.95 ± 0.02	0.0HisXaa: 0.0 ± 0.0
Ile	5.63IleAla: 5.63 ± 0.056	0.63IleCys: 0.63 ± 0.019	3.507IleAsp: 3.507 ± 0.04	3.067IleGlu: 3.067 ± 0.046	2.798IlePhe: 2.798 ± 0.044	4.459IleGly: 4.459 ± 0.05	1.314IleHis: 1.314 ± 0.028	4.384IleIle: 4.384 ± 0.053	3.725IleLys: 3.725 ± 0.044	5.686IleLeu: 5.686 ± 0.056	1.347IleMet: 1.347 ± 0.026	3.686IleAsn: 3.686 ± 0.048	3.228IlePro: 3.228 ± 0.042	2.237IleGln: 2.237 ± 0.03	3.439IleArg: 3.439 ± 0.043	4.877IleSer: 4.877 ± 0.044	4.892IleThr: 4.892 ± 0.065	3.871IleVal: 3.871 ± 0.042	0.742IleTrp: 0.742 ± 0.018	2.509IleTyr: 2.509 ± 0.037	0.0IleXaa: 0.0 ± 0.0
Lys	4.882LysAla: 4.882 ± 0.048	0.297LysCys: 0.297 ± 0.013	3.871LysAsp: 3.871 ± 0.043	4.221LysGlu: 4.221 ± 0.055	2.023LysPhe: 2.023 ± 0.031	4.387LysGly: 4.387 ± 0.052	1.13LysHis: 1.13 ± 0.023	4.011LysIle: 4.011 ± 0.046	4.551LysLys: 4.551 ± 0.061	5.228LysLeu: 5.228 ± 0.05	1.767LysMet: 1.767 ± 0.028	3.334LysAsn: 3.334 ± 0.038	2.525LysPro: 2.525 ± 0.035	2.708LysGln: 2.708 ± 0.036	2.506LysArg: 2.506 ± 0.037	3.234LysSer: 3.234 ± 0.037	3.582LysThr: 3.582 ± 0.04	4.102LysVal: 4.102 ± 0.048	0.792LysTrp: 0.792 ± 0.021	2.541LysTyr: 2.541 ± 0.033	0.0LysXaa: 0.0 ± 0.0
Leu	7.047LeuAla: 7.047 ± 0.072	0.84LeuCys: 0.84 ± 0.019	4.495LeuAsp: 4.495 ± 0.046	4.956LeuGlu: 4.956 ± 0.05	4.453LeuPhe: 4.453 ± 0.05	5.681LeuGly: 5.681 ± 0.05	2.028LeuHis: 2.028 ± 0.034	5.505LeuIle: 5.505 ± 0.057	6.19LeuLys: 6.19 ± 0.057	10.525LeuLeu: 10.525 ± 0.097	2.192LeuMet: 2.192 ± 0.032	4.767LeuAsn: 4.767 ± 0.051	4.783LeuPro: 4.783 ± 0.049	4.756LeuGln: 4.756 ± 0.057	4.193LeuArg: 4.193 ± 0.042	6.642LeuSer: 6.642 ± 0.061	5.688LeuThr: 5.688 ± 0.051	5.565LeuVal: 5.565 ± 0.053	1.029LeuTrp: 1.029 ± 0.022	3.486LeuTyr: 3.486 ± 0.047	0.0LeuXaa: 0.0 ± 0.0
Met	1.941MetAla: 1.941 ± 0.032	0.143MetCys: 0.143 ± 0.008	1.311MetAsp: 1.311 ± 0.023	1.519MetGlu: 1.519 ± 0.027	0.824MetPhe: 0.824 ± 0.019	1.62MetGly: 1.62 ± 0.032	0.463MetHis: 0.463 ± 0.013	1.475MetIle: 1.475 ± 0.029	2.004MetLys: 2.004 ± 0.03	2.294MetLeu: 2.294 ± 0.035	0.673MetMet: 0.673 ± 0.019	1.352MetAsn: 1.352 ± 0.022	1.209MetPro: 1.209 ± 0.022	1.185MetGln: 1.185 ± 0.025	1.084MetArg: 1.084 ± 0.021	1.387MetSer: 1.387 ± 0.026	1.151MetThr: 1.151 ± 0.025	1.397MetVal: 1.397 ± 0.026	0.224MetTrp: 0.224 ± 0.009	0.737MetTyr: 0.737 ± 0.018	0.0MetXaa: 0.0 ± 0.0
Asn	4.116AsnAla: 4.116 ± 0.054	0.368AsnCys: 0.368 ± 0.014	2.685AsnAsp: 2.685 ± 0.04	2.609AsnGlu: 2.609 ± 0.034	2.27AsnPhe: 2.27 ± 0.036	4.36AsnGly: 4.36 ± 0.071	0.858AsnHis: 0.858 ± 0.018	3.992AsnIle: 3.992 ± 0.051	3.258AsnLys: 3.258 ± 0.038	4.205AsnLeu: 4.205 ± 0.052	1.215AsnMet: 1.215 ± 0.019	3.307AsnAsn: 3.307 ± 0.052	2.676AsnPro: 2.676 ± 0.04	1.765AsnGln: 1.765 ± 0.031	2.449AsnArg: 2.449 ± 0.033	3.088AsnSer: 3.088 ± 0.044	3.592AsnThr: 3.592 ± 0.062	3.222AsnVal: 3.222 ± 0.046	0.741AsnTrp: 0.741 ± 0.02	2.479AsnTyr: 2.479 ± 0.04	0.0AsnXaa: 0.0 ± 0.0
Pro	4.702ProAla: 4.702 ± 0.071	0.234ProCys: 0.234 ± 0.012	2.914ProAsp: 2.914 ± 0.037	2.982ProGlu: 2.982 ± 0.041	2.026ProPhe: 2.026 ± 0.029	3.818ProGly: 3.818 ± 0.041	0.771ProHis: 0.771 ± 0.018	1.927ProIle: 1.927 ± 0.027	1.781ProLys: 1.781 ± 0.03	3.817ProLeu: 3.817 ± 0.04	0.839ProMet: 0.839 ± 0.02	1.736ProAsn: 1.736 ± 0.03	1.447ProPro: 1.447 ± 0.03	1.506ProGln: 1.506 ± 0.026	1.403ProArg: 1.403 ± 0.024	2.237ProSer: 2.237 ± 0.032	1.951ProThr: 1.951 ± 0.034	4.175ProVal: 4.175 ± 0.053	0.51ProTrp: 0.51 ± 0.016	1.684ProTyr: 1.684 ± 0.029	0.0ProXaa: 0.0 ± 0.0
Gln	2.924GlnAla: 2.924 ± 0.038	0.236GlnCys: 0.236 ± 0.01	1.637GlnAsp: 1.637 ± 0.032	2.249GlnGlu: 2.249 ± 0.035	1.721GlnPhe: 1.721 ± 0.026	2.225GlnGly: 2.225 ± 0.03	1.08GlnHis: 1.08 ± 0.022	2.146GlnIle: 2.146 ± 0.031	2.182GlnLys: 2.182 ± 0.031	4.816GlnLeu: 4.816 ± 0.055	0.953GlnMet: 0.953 ± 0.021	1.719GlnAsn: 1.719 ± 0.035	1.941GlnPro: 1.941 ± 0.031	3.061GlnGln: 3.061 ± 0.051	1.872GlnArg: 1.872 ± 0.031	2.183GlnSer: 2.183 ± 0.031	2.192GlnThr: 2.192 ± 0.036	2.735GlnVal: 2.735 ± 0.04	0.578GlnTrp: 0.578 ± 0.016	1.808GlnTyr: 1.808 ± 0.028	0.0GlnXaa: 0.0 ± 0.0
Arg	2.78ArgAla: 2.78 ± 0.03	0.266ArgCys: 0.266 ± 0.009	2.083ArgAsp: 2.083 ± 0.031	2.662ArgGlu: 2.662 ± 0.039	2.339ArgPhe: 2.339 ± 0.034	2.333ArgGly: 2.333 ± 0.033	0.873ArgHis: 0.873 ± 0.022	3.293ArgIle: 3.293 ± 0.036	3.058ArgLys: 3.058 ± 0.036	4.295ArgLeu: 4.295 ± 0.046	1.225ArgMet: 1.225 ± 0.023	2.589ArgAsn: 2.589 ± 0.04	1.534ArgPro: 1.534 ± 0.026	1.944ArgGln: 1.944 ± 0.03	1.946ArgArg: 1.946 ± 0.032	2.432ArgSer: 2.432 ± 0.031	2.3ArgThr: 2.3 ± 0.03	2.6ArgVal: 2.6 ± 0.033	0.722ArgTrp: 0.722 ± 0.016	2.179ArgTyr: 2.179 ± 0.035	0.0ArgXaa: 0.0 ± 0.0
Ser	4.988SerAla: 4.988 ± 0.059	0.565SerCys: 0.565 ± 0.016	2.886SerAsp: 2.886 ± 0.033	2.62SerGlu: 2.62 ± 0.04	3.374SerPhe: 3.374 ± 0.039	5.128SerGly: 5.128 ± 0.059	1.086SerHis: 1.086 ± 0.022	4.08SerIle: 4.08 ± 0.042	3.069SerLys: 3.069 ± 0.035	6.263SerLeu: 6.263 ± 0.049	1.429SerMet: 1.429 ± 0.024	3.056SerAsn: 3.056 ± 0.045	2.538SerPro: 2.538 ± 0.034	2.003SerGln: 2.003 ± 0.032	2.818SerArg: 2.818 ± 0.036	3.936SerSer: 3.936 ± 0.056	3.571SerThr: 3.571 ± 0.044	4.11SerVal: 4.11 ± 0.049	0.951SerTrp: 0.951 ± 0.021	2.777SerTyr: 2.777 ± 0.043	0.0SerXaa: 0.0 ± 0.0
Thr	5.842ThrAla: 5.842 ± 0.08	0.385ThrCys: 0.385 ± 0.014	3.558ThrAsp: 3.558 ± 0.048	2.667ThrGlu: 2.667 ± 0.032	2.807ThrPhe: 2.807 ± 0.037	5.715ThrGly: 5.715 ± 0.077	1.094ThrHis: 1.094 ± 0.021	4.13ThrIle: 4.13 ± 0.053	2.793ThrLys: 2.793 ± 0.03	5.717ThrLeu: 5.717 ± 0.06	1.13ThrMet: 1.13 ± 0.021	2.893ThrAsn: 2.893 ± 0.058	3.149ThrPro: 3.149 ± 0.038	1.971ThrGln: 1.971 ± 0.03	2.431ThrArg: 2.431 ± 0.032	3.583ThrSer: 3.583 ± 0.06	4.04ThrThr: 4.04 ± 0.058	4.379ThrVal: 4.379 ± 0.078	0.822ThrTrp: 0.822 ± 0.02	2.459ThrTyr: 2.459 ± 0.041	0.0ThrXaa: 0.0 ± 0.0
Val	5.172ValAla: 5.172 ± 0.053	0.554ValCys: 0.554 ± 0.017	3.007ValAsp: 3.007 ± 0.035	2.915ValGlu: 2.915 ± 0.042	2.976ValPhe: 2.976 ± 0.037	3.493ValGly: 3.493 ± 0.042	1.157ValHis: 1.157 ± 0.027	4.623ValIle: 4.623 ± 0.05	4.527ValLys: 4.527 ± 0.051	6.251ValLeu: 6.251 ± 0.058	1.669ValMet: 1.669 ± 0.029	3.792ValAsn: 3.792 ± 0.054	2.894ValPro: 2.894 ± 0.04	2.373ValGln: 2.373 ± 0.032	2.553ValArg: 2.553 ± 0.035	4.466ValSer: 4.466 ± 0.047	4.641ValThr: 4.641 ± 0.08	4.331ValVal: 4.331 ± 0.05	0.757ValTrp: 0.757 ± 0.019	2.668ValTyr: 2.668 ± 0.033	0.0ValXaa: 0.0 ± 0.0
Trp	0.844TrpAla: 0.844 ± 0.02	0.136TrpCys: 0.136 ± 0.008	0.686TrpAsp: 0.686 ± 0.02	0.793TrpGlu: 0.793 ± 0.02	0.576TrpPhe: 0.576 ± 0.014	0.938TrpGly: 0.938 ± 0.021	0.301TrpHis: 0.301 ± 0.011	0.784TrpIle: 0.784 ± 0.018	0.95TrpLys: 0.95 ± 0.021	1.391TrpLeu: 1.391 ± 0.026	0.405TrpMet: 0.405 ± 0.014	0.762TrpAsn: 0.762 ± 0.018	0.415TrpPro: 0.415 ± 0.013	0.728TrpGln: 0.728 ± 0.018	0.605TrpArg: 0.605 ± 0.017	0.765TrpSer: 0.765 ± 0.018	0.715TrpThr: 0.715 ± 0.019	0.734TrpVal: 0.734 ± 0.019	0.272TrpTrp: 0.272 ± 0.012	0.568TrpTyr: 0.568 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	3.093TyrAla: 3.093 ± 0.037	0.355TyrCys: 0.355 ± 0.013	2.314TyrAsp: 2.314 ± 0.04	2.055TyrGlu: 2.055 ± 0.033	2.195TyrPhe: 2.195 ± 0.033	2.907TyrGly: 2.907 ± 0.037	0.917TyrHis: 0.917 ± 0.019	2.389TyrIle: 2.389 ± 0.034	2.43TyrLys: 2.43 ± 0.033	3.943TyrLeu: 3.943 ± 0.045	0.859TyrMet: 0.859 ± 0.021	2.588TyrAsn: 2.588 ± 0.039	1.855TyrPro: 1.855 ± 0.027	1.698TyrGln: 1.698 ± 0.027	2.088TyrArg: 2.088 ± 0.031	2.64TyrSer: 2.64 ± 0.039	2.897TyrThr: 2.897 ± 0.05	2.269TyrVal: 2.269 ± 0.035	0.586TyrTrp: 0.586 ± 0.017	2.037TyrTyr: 2.037 ± 0.038	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 6304 proteins (2401850 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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