Amino acid dipepetide frequency for Desulfallas thermosapovorans DSM 6562

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.576AlaAla: 9.576 ± 0.15	1.16AlaCys: 1.16 ± 0.041	4.132AlaAsp: 4.132 ± 0.076	5.515AlaGlu: 5.515 ± 0.093	2.644AlaPhe: 2.644 ± 0.07	9.309AlaGly: 9.309 ± 0.151	1.392AlaHis: 1.392 ± 0.043	5.206AlaIle: 5.206 ± 0.096	3.799AlaLys: 3.799 ± 0.085	9.454AlaLeu: 9.454 ± 0.131	2.669AlaMet: 2.669 ± 0.067	2.696AlaAsn: 2.696 ± 0.055	2.912AlaPro: 2.912 ± 0.061	2.722AlaGln: 2.722 ± 0.055	6.323AlaArg: 6.323 ± 0.092	3.804AlaSer: 3.804 ± 0.076	3.777AlaThr: 3.777 ± 0.084	7.915AlaVal: 7.915 ± 0.109	0.735AlaTrp: 0.735 ± 0.027	2.263AlaTyr: 2.263 ± 0.057	0.0AlaXaa: 0.0 ± 0.0
Cys	1.015CysAla: 1.015 ± 0.039	0.26CysCys: 0.26 ± 0.019	0.576CysAsp: 0.576 ± 0.025	0.513CysGlu: 0.513 ± 0.027	0.406CysPhe: 0.406 ± 0.022	1.354CysGly: 1.354 ± 0.047	0.308CysHis: 0.308 ± 0.02	0.667CysIle: 0.667 ± 0.031	0.476CysLys: 0.476 ± 0.025	1.169CysLeu: 1.169 ± 0.035	0.315CysMet: 0.315 ± 0.018	0.448CysAsn: 0.448 ± 0.022	0.821CysPro: 0.821 ± 0.038	0.391CysGln: 0.391 ± 0.022	0.944CysArg: 0.944 ± 0.034	0.757CysSer: 0.757 ± 0.033	0.665CysThr: 0.665 ± 0.028	0.722CysVal: 0.722 ± 0.03	0.094CysTrp: 0.094 ± 0.01	0.379CysTyr: 0.379 ± 0.022	0.0CysXaa: 0.0 ± 0.0
Asp	3.652AspAla: 3.652 ± 0.062	0.605AspCys: 0.605 ± 0.027	2.336AspAsp: 2.336 ± 0.052	3.541AspGlu: 3.541 ± 0.073	2.179AspPhe: 2.179 ± 0.044	3.67AspGly: 3.67 ± 0.087	0.924AspHis: 0.924 ± 0.033	4.337AspIle: 4.337 ± 0.078	3.032AspLys: 3.032 ± 0.067	5.056AspLeu: 5.056 ± 0.077	1.61AspMet: 1.61 ± 0.045	2.173AspAsn: 2.173 ± 0.056	2.451AspPro: 2.451 ± 0.054	1.447AspGln: 1.447 ± 0.046	3.005AspArg: 3.005 ± 0.07	2.08AspSer: 2.08 ± 0.052	2.466AspThr: 2.466 ± 0.055	3.733AspVal: 3.733 ± 0.071	0.526AspTrp: 0.526 ± 0.026	2.033AspTyr: 2.033 ± 0.053	0.0AspXaa: 0.0 ± 0.0
Glu	5.54GluAla: 5.54 ± 0.082	0.571GluCys: 0.571 ± 0.03	2.942GluAsp: 2.942 ± 0.066	5.009GluGlu: 5.009 ± 0.086	2.017GluPhe: 2.017 ± 0.054	4.032GluGly: 4.032 ± 0.065	1.343GluHis: 1.343 ± 0.037	5.099GluIle: 5.099 ± 0.09	4.969GluLys: 4.969 ± 0.081	7.145GluLeu: 7.145 ± 0.104	1.908GluMet: 1.908 ± 0.048	2.88GluAsn: 2.88 ± 0.061	2.304GluPro: 2.304 ± 0.06	3.244GluGln: 3.244 ± 0.074	3.62GluArg: 3.62 ± 0.08	2.577GluSer: 2.577 ± 0.052	3.0GluThr: 3.0 ± 0.059	4.888GluVal: 4.888 ± 0.081	0.54GluTrp: 0.54 ± 0.027	2.0GluTyr: 2.0 ± 0.054	0.0GluXaa: 0.0 ± 0.0
Phe	2.961PheAla: 2.961 ± 0.066	0.533PheCys: 0.533 ± 0.026	1.931PheAsp: 1.931 ± 0.053	1.899PheGlu: 1.899 ± 0.048	1.588PhePhe: 1.588 ± 0.044	2.875PheGly: 2.875 ± 0.062	0.671PheHis: 0.671 ± 0.027	2.837PheIle: 2.837 ± 0.066	1.964PheLys: 1.964 ± 0.049	3.353PheLeu: 3.353 ± 0.069	1.043PheMet: 1.043 ± 0.038	1.751PheAsn: 1.751 ± 0.046	1.437PhePro: 1.437 ± 0.042	0.959PheGln: 0.959 ± 0.033	1.607PheArg: 1.607 ± 0.046	2.142PheSer: 2.142 ± 0.054	2.21PheThr: 2.21 ± 0.051	2.472PheVal: 2.472 ± 0.053	0.435PheTrp: 0.435 ± 0.023	1.38PheTyr: 1.38 ± 0.048	0.0PheXaa: 0.0 ± 0.0
Gly	6.591GlyAla: 6.591 ± 0.109	1.173GlyCys: 1.173 ± 0.039	4.141GlyAsp: 4.141 ± 0.09	5.063GlyGlu: 5.063 ± 0.098	3.149GlyPhe: 3.149 ± 0.072	6.461GlyGly: 6.461 ± 0.118	1.688GlyHis: 1.688 ± 0.045	5.797GlyIle: 5.797 ± 0.099	4.827GlyLys: 4.827 ± 0.071	8.27GlyLeu: 8.27 ± 0.114	2.427GlyMet: 2.427 ± 0.054	2.911GlyAsn: 2.911 ± 0.058	2.601GlyPro: 2.601 ± 0.052	3.153GlyGln: 3.153 ± 0.063	4.632GlyArg: 4.632 ± 0.08	3.813GlySer: 3.813 ± 0.071	4.418GlyThr: 4.418 ± 0.089	6.527GlyVal: 6.527 ± 0.105	0.878GlyTrp: 0.878 ± 0.033	2.933GlyTyr: 2.933 ± 0.057	0.0GlyXaa: 0.0 ± 0.0
His	1.381HisAla: 1.381 ± 0.038	0.308HisCys: 0.308 ± 0.019	0.965HisAsp: 0.965 ± 0.036	0.961HisGlu: 0.961 ± 0.035	0.75HisPhe: 0.75 ± 0.03	1.617HisGly: 1.617 ± 0.047	0.492HisHis: 0.492 ± 0.026	1.369HisIle: 1.369 ± 0.039	0.874HisLys: 0.874 ± 0.033	1.874HisLeu: 1.874 ± 0.048	0.565HisMet: 0.565 ± 0.026	0.813HisAsn: 0.813 ± 0.031	1.132HisPro: 1.132 ± 0.036	0.622HisGln: 0.622 ± 0.03	1.348HisArg: 1.348 ± 0.045	0.884HisSer: 0.884 ± 0.034	1.043HisThr: 1.043 ± 0.039	1.207HisVal: 1.207 ± 0.037	0.232HisTrp: 0.232 ± 0.019	0.739HisTyr: 0.739 ± 0.03	0.0HisXaa: 0.0 ± 0.0
Ile	5.831IleAla: 5.831 ± 0.091	0.839IleCys: 0.839 ± 0.029	3.647IleAsp: 3.647 ± 0.06	3.979IleGlu: 3.979 ± 0.087	2.502IlePhe: 2.502 ± 0.055	4.502IleGly: 4.502 ± 0.087	1.199IleHis: 1.199 ± 0.043	5.281IleIle: 5.281 ± 0.102	4.578IleLys: 4.578 ± 0.065	5.942IleLeu: 5.942 ± 0.087	1.868IleMet: 1.868 ± 0.048	3.598IleAsn: 3.598 ± 0.069	3.215IlePro: 3.215 ± 0.06	1.778IleGln: 1.778 ± 0.042	3.193IleArg: 3.193 ± 0.059	4.006IleSer: 4.006 ± 0.071	4.363IleThr: 4.363 ± 0.075	4.22IleVal: 4.22 ± 0.072	0.555IleTrp: 0.555 ± 0.029	2.135IleTyr: 2.135 ± 0.044	0.0IleXaa: 0.0 ± 0.0
Lys	4.304LysAla: 4.304 ± 0.078	0.57LysCys: 0.57 ± 0.032	2.799LysAsp: 2.799 ± 0.061	4.201LysGlu: 4.201 ± 0.077	1.62LysPhe: 1.62 ± 0.045	3.654LysGly: 3.654 ± 0.069	1.042LysHis: 1.042 ± 0.036	4.077LysIle: 4.077 ± 0.078	3.878LysLys: 3.878 ± 0.084	5.095LysLeu: 5.095 ± 0.075	1.696LysMet: 1.696 ± 0.048	2.538LysAsn: 2.538 ± 0.059	2.461LysPro: 2.461 ± 0.054	2.113LysGln: 2.113 ± 0.049	2.807LysArg: 2.807 ± 0.062	2.478LysSer: 2.478 ± 0.063	2.865LysThr: 2.865 ± 0.059	4.045LysVal: 4.045 ± 0.078	0.443LysTrp: 0.443 ± 0.024	1.993LysTyr: 1.993 ± 0.051	0.0LysXaa: 0.0 ± 0.0
Leu	10.716LeuAla: 10.716 ± 0.121	1.139LeuCys: 1.139 ± 0.039	5.321LeuAsp: 5.321 ± 0.077	6.793LeuGlu: 6.793 ± 0.102	3.503LeuPhe: 3.503 ± 0.072	7.801LeuGly: 7.801 ± 0.126	1.917LeuHis: 1.917 ± 0.05	5.529LeuIle: 5.529 ± 0.1	5.374LeuLys: 5.374 ± 0.088	10.174LeuLeu: 10.174 ± 0.138	2.373LeuMet: 2.373 ± 0.061	3.847LeuAsn: 3.847 ± 0.066	4.952LeuPro: 4.952 ± 0.076	3.808LeuGln: 3.808 ± 0.078	5.142LeuArg: 5.142 ± 0.076	5.244LeuSer: 5.244 ± 0.073	5.126LeuThr: 5.126 ± 0.068	8.25LeuVal: 8.25 ± 0.116	0.892LeuTrp: 0.892 ± 0.032	2.765LeuTyr: 2.765 ± 0.059	0.0LeuXaa: 0.0 ± 0.0
Met	2.943MetAla: 2.943 ± 0.077	0.287MetCys: 0.287 ± 0.02	1.565MetAsp: 1.565 ± 0.044	2.005MetGlu: 2.005 ± 0.053	0.878MetPhe: 0.878 ± 0.031	2.229MetGly: 2.229 ± 0.059	0.561MetHis: 0.561 ± 0.024	1.56MetIle: 1.56 ± 0.044	1.313MetLys: 1.313 ± 0.039	2.795MetLeu: 2.795 ± 0.055	0.609MetMet: 0.609 ± 0.028	1.0MetAsn: 1.0 ± 0.032	1.302MetPro: 1.302 ± 0.041	1.144MetGln: 1.144 ± 0.036	1.411MetArg: 1.411 ± 0.046	1.468MetSer: 1.468 ± 0.041	1.319MetThr: 1.319 ± 0.036	2.266MetVal: 2.266 ± 0.055	0.164MetTrp: 0.164 ± 0.013	0.67MetTyr: 0.67 ± 0.028	0.0MetXaa: 0.0 ± 0.0
Asn	2.909AsnAla: 2.909 ± 0.063	0.558AsnCys: 0.558 ± 0.028	1.802AsnAsp: 1.802 ± 0.052	2.241AsnGlu: 2.241 ± 0.055	1.428AsnPhe: 1.428 ± 0.042	2.675AsnGly: 2.675 ± 0.055	0.763AsnHis: 0.763 ± 0.028	3.322AsnIle: 3.322 ± 0.066	2.362AsnLys: 2.362 ± 0.058	3.967AsnLeu: 3.967 ± 0.073	1.192AsnMet: 1.192 ± 0.043	1.944AsnAsn: 1.944 ± 0.056	2.364AsnPro: 2.364 ± 0.055	1.406AsnGln: 1.406 ± 0.048	2.346AsnArg: 2.346 ± 0.052	1.937AsnSer: 1.937 ± 0.056	2.046AsnThr: 2.046 ± 0.05	2.627AsnVal: 2.627 ± 0.055	0.447AsnTrp: 0.447 ± 0.026	1.468AsnTyr: 1.468 ± 0.042	0.0AsnXaa: 0.0 ± 0.0
Pro	3.95ProAla: 3.95 ± 0.08	0.451ProCys: 0.451 ± 0.025	2.557ProAsp: 2.557 ± 0.059	3.65ProGlu: 3.65 ± 0.068	1.547ProPhe: 1.547 ± 0.048	5.137ProGly: 5.137 ± 0.095	0.847ProHis: 0.847 ± 0.031	1.816ProIle: 1.816 ± 0.045	1.803ProLys: 1.803 ± 0.052	4.011ProLeu: 4.011 ± 0.07	0.896ProMet: 0.896 ± 0.031	1.348ProAsn: 1.348 ± 0.04	1.895ProPro: 1.895 ± 0.053	1.358ProGln: 1.358 ± 0.043	2.566ProArg: 2.566 ± 0.051	1.791ProSer: 1.791 ± 0.05	1.76ProThr: 1.76 ± 0.056	4.809ProVal: 4.809 ± 0.073	0.426ProTrp: 0.426 ± 0.021	1.292ProTyr: 1.292 ± 0.04	0.0ProXaa: 0.0 ± 0.0
Gln	3.403GlnAla: 3.403 ± 0.068	0.404GlnCys: 0.404 ± 0.021	1.502GlnAsp: 1.502 ± 0.039	2.453GlnGlu: 2.453 ± 0.056	1.157GlnPhe: 1.157 ± 0.037	2.385GlnGly: 2.385 ± 0.059	0.651GlnHis: 0.651 ± 0.029	2.318GlnIle: 2.318 ± 0.05	2.164GlnLys: 2.164 ± 0.062	3.652GlnLeu: 3.652 ± 0.069	1.044GlnMet: 1.044 ± 0.033	1.421GlnAsn: 1.421 ± 0.047	1.381GlnPro: 1.381 ± 0.042	1.752GlnGln: 1.752 ± 0.057	2.123GlnArg: 2.123 ± 0.057	1.64GlnSer: 1.64 ± 0.049	1.636GlnThr: 1.636 ± 0.046	3.155GlnVal: 3.155 ± 0.062	0.393GlnTrp: 0.393 ± 0.023	1.116GlnTyr: 1.116 ± 0.037	0.0GlnXaa: 0.0 ± 0.0
Arg	4.596ArgAla: 4.596 ± 0.088	0.71ArgCys: 0.71 ± 0.031	3.254ArgAsp: 3.254 ± 0.061	5.027ArgGlu: 5.027 ± 0.094	2.038ArgPhe: 2.038 ± 0.052	4.097ArgGly: 4.097 ± 0.065	1.159ArgHis: 1.159 ± 0.037	3.434ArgIle: 3.434 ± 0.068	2.942ArgLys: 2.942 ± 0.061	5.986ArgLeu: 5.986 ± 0.098	1.585ArgMet: 1.585 ± 0.047	1.993ArgAsn: 1.993 ± 0.048	2.312ArgPro: 2.312 ± 0.054	2.554ArgGln: 2.554 ± 0.067	3.663ArgArg: 3.663 ± 0.078	2.468ArgSer: 2.468 ± 0.053	2.368ArgThr: 2.368 ± 0.053	4.8ArgVal: 4.8 ± 0.083	0.676ArgTrp: 0.676 ± 0.032	1.977ArgTyr: 1.977 ± 0.06	0.0ArgXaa: 0.0 ± 0.0
Ser	3.772SerAla: 3.772 ± 0.068	0.656SerCys: 0.656 ± 0.034	2.302SerAsp: 2.302 ± 0.06	2.619SerGlu: 2.619 ± 0.063	2.122SerPhe: 2.122 ± 0.057	4.902SerGly: 4.902 ± 0.083	0.931SerHis: 0.931 ± 0.033	3.38SerIle: 3.38 ± 0.075	2.284SerLys: 2.284 ± 0.051	4.955SerLeu: 4.955 ± 0.077	1.36SerMet: 1.36 ± 0.038	1.784SerAsn: 1.784 ± 0.049	2.317SerPro: 2.317 ± 0.053	1.505SerGln: 1.505 ± 0.049	3.017SerArg: 3.017 ± 0.068	2.722SerSer: 2.722 ± 0.075	2.509SerThr: 2.509 ± 0.051	3.352SerVal: 3.352 ± 0.069	0.451SerTrp: 0.451 ± 0.024	1.514SerTyr: 1.514 ± 0.044	0.0SerXaa: 0.0 ± 0.0
Thr	4.727ThrAla: 4.727 ± 0.072	0.571ThrCys: 0.571 ± 0.03	2.371ThrAsp: 2.371 ± 0.06	2.638ThrGlu: 2.638 ± 0.053	1.764ThrPhe: 1.764 ± 0.046	6.2ThrGly: 6.2 ± 0.102	0.869ThrHis: 0.869 ± 0.033	3.201ThrIle: 3.201 ± 0.066	2.031ThrLys: 2.031 ± 0.055	4.92ThrLeu: 4.92 ± 0.076	1.262ThrMet: 1.262 ± 0.042	1.701ThrAsn: 1.701 ± 0.048	2.548ThrPro: 2.548 ± 0.058	1.229ThrGln: 1.229 ± 0.045	2.939ThrArg: 2.939 ± 0.057	2.545ThrSer: 2.545 ± 0.059	2.695ThrThr: 2.695 ± 0.06	4.608ThrVal: 4.608 ± 0.089	0.474ThrTrp: 0.474 ± 0.025	1.402ThrTyr: 1.402 ± 0.043	0.0ThrXaa: 0.0 ± 0.0
Val	7.023ValAla: 7.023 ± 0.089	0.943ValCys: 0.943 ± 0.039	4.511ValAsp: 4.511 ± 0.082	5.2ValGlu: 5.2 ± 0.086	3.012ValPhe: 3.012 ± 0.054	5.297ValGly: 5.297 ± 0.083	1.437ValHis: 1.437 ± 0.046	5.409ValIle: 5.409 ± 0.097	4.091ValLys: 4.091 ± 0.073	8.236ValLeu: 8.236 ± 0.118	2.073ValMet: 2.073 ± 0.042	3.148ValAsn: 3.148 ± 0.061	3.607ValPro: 3.607 ± 0.068	2.781ValGln: 2.781 ± 0.06	4.167ValArg: 4.167 ± 0.074	4.009ValSer: 4.009 ± 0.068	4.384ValThr: 4.384 ± 0.073	6.47ValVal: 6.47 ± 0.104	0.596ValTrp: 0.596 ± 0.029	2.364ValTyr: 2.364 ± 0.056	0.0ValXaa: 0.0 ± 0.0
Trp	0.692TrpAla: 0.692 ± 0.028	0.107TrpCys: 0.107 ± 0.013	0.538TrpAsp: 0.538 ± 0.027	0.677TrpGlu: 0.677 ± 0.03	0.384TrpPhe: 0.384 ± 0.022	0.746TrpGly: 0.746 ± 0.031	0.237TrpHis: 0.237 ± 0.016	0.479TrpIle: 0.479 ± 0.028	0.387TrpLys: 0.387 ± 0.024	1.163TrpLeu: 1.163 ± 0.049	0.236TrpMet: 0.236 ± 0.018	0.328TrpAsn: 0.328 ± 0.019	0.429TrpPro: 0.429 ± 0.022	0.511TrpGln: 0.511 ± 0.028	0.564TrpArg: 0.564 ± 0.027	0.482TrpSer: 0.482 ± 0.025	0.371TrpThr: 0.371 ± 0.024	0.676TrpVal: 0.676 ± 0.028	0.143TrpTrp: 0.143 ± 0.015	0.319TrpTyr: 0.319 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.421TyrAla: 2.421 ± 0.053	0.436TyrCys: 0.436 ± 0.025	1.666TyrAsp: 1.666 ± 0.044	1.647TyrGlu: 1.647 ± 0.047	1.36TyrPhe: 1.36 ± 0.037	2.51TyrGly: 2.51 ± 0.053	0.747TyrHis: 0.747 ± 0.03	2.11TyrIle: 2.11 ± 0.049	1.532TyrLys: 1.532 ± 0.048	3.451TyrLeu: 3.451 ± 0.072	0.759TyrMet: 0.759 ± 0.032	1.483TyrAsn: 1.483 ± 0.043	1.47TyrPro: 1.47 ± 0.043	1.272TyrGln: 1.272 ± 0.039	2.224TyrArg: 2.224 ± 0.058	1.603TyrSer: 1.603 ± 0.046	1.671TyrThr: 1.671 ± 0.043	2.013TyrVal: 2.013 ± 0.056	0.368TyrTrp: 0.368 ± 0.021	1.277TyrTyr: 1.277 ± 0.044	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2860 proteins (839009 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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