Amino acid dipepetide frequency for Tortoise microvirus 45

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.436AlaAla: 3.436 ± 2.063
1.145AlaCys: 1.145 ± 0.558
4.009AlaAsp: 4.009 ± 1.049
4.009AlaGlu: 4.009 ± 1.444
4.009AlaPhe: 4.009 ± 1.612
4.009AlaGly: 4.009 ± 1.533
1.145AlaHis: 1.145 ± 0.902
1.718AlaIle: 1.718 ± 0.852
5.155AlaLys: 5.155 ± 2.115
8.591AlaLeu: 8.591 ± 1.205
2.864AlaMet: 2.864 ± 1.405
4.582AlaAsn: 4.582 ± 3.202
4.582AlaPro: 4.582 ± 1.371
3.436AlaGln: 3.436 ± 1.103
2.864AlaArg: 2.864 ± 0.63
4.582AlaSer: 4.582 ± 1.129
4.009AlaThr: 4.009 ± 1.277
5.155AlaVal: 5.155 ± 1.428
0.0AlaTrp: 0.0 ± 0.0
2.864AlaTyr: 2.864 ± 0.963
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
1.718CysCys: 1.718 ± 1.306
1.718CysAsp: 1.718 ± 0.942
0.0CysGlu: 0.0 ± 0.0
2.291CysPhe: 2.291 ± 1.595
1.145CysGly: 1.145 ± 0.902
0.0CysHis: 0.0 ± 0.0
0.573CysIle: 0.573 ± 0.604
2.291CysLys: 2.291 ± 1.349
2.864CysLeu: 2.864 ± 1.841
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.573CysPro: 0.573 ± 0.711
0.573CysGln: 0.573 ± 0.381
1.145CysArg: 1.145 ± 0.558
0.0CysSer: 0.0 ± 0.0
1.145CysThr: 1.145 ± 0.728
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
1.145CysTyr: 1.145 ± 0.902
0.0CysXaa: 0.0 ± 0.0
Asp
4.009AspAla: 4.009 ± 2.44
2.864AspCys: 2.864 ± 1.216
6.873AspAsp: 6.873 ± 1.786
3.436AspGlu: 3.436 ± 0.796
5.155AspPhe: 5.155 ± 1.495
2.291AspGly: 2.291 ± 1.319
0.573AspHis: 0.573 ± 0.711
6.873AspIle: 6.873 ± 2.119
2.291AspLys: 2.291 ± 1.212
4.009AspLeu: 4.009 ± 0.711
0.573AspMet: 0.573 ± 0.381
4.009AspAsn: 4.009 ± 0.9
1.718AspPro: 1.718 ± 0.705
1.718AspGln: 1.718 ± 0.852
3.436AspArg: 3.436 ± 0.716
4.582AspSer: 4.582 ± 2.869
4.009AspThr: 4.009 ± 1.399
2.864AspVal: 2.864 ± 1.724
0.573AspTrp: 0.573 ± 0.549
5.727AspTyr: 5.727 ± 1.783
0.0AspXaa: 0.0 ± 0.0
Glu
4.009GluAla: 4.009 ± 2.095
0.0GluCys: 0.0 ± 0.0
1.718GluAsp: 1.718 ± 0.672
1.145GluGlu: 1.145 ± 0.961
0.573GluPhe: 0.573 ± 0.711
0.573GluGly: 0.573 ± 0.711
0.0GluHis: 0.0 ± 0.0
3.436GluIle: 3.436 ± 0.709
1.718GluLys: 1.718 ± 0.871
8.591GluLeu: 8.591 ± 1.547
1.718GluMet: 1.718 ± 1.096
1.145GluAsn: 1.145 ± 0.674
2.291GluPro: 2.291 ± 1.262
0.573GluGln: 0.573 ± 0.48
3.436GluArg: 3.436 ± 1.108
4.009GluSer: 4.009 ± 1.931
2.864GluThr: 2.864 ± 0.963
2.864GluVal: 2.864 ± 1.567
0.573GluTrp: 0.573 ± 0.69
2.291GluTyr: 2.291 ± 1.735
0.0GluXaa: 0.0 ± 0.0
Phe
5.155PheAla: 5.155 ± 1.492
1.718PheCys: 1.718 ± 1.541
6.3PheAsp: 6.3 ± 2.763
1.718PheGlu: 1.718 ± 0.686
2.864PhePhe: 2.864 ± 1.121
2.864PheGly: 2.864 ± 0.63
1.145PheHis: 1.145 ± 0.846
1.145PheIle: 1.145 ± 0.558
3.436PheLys: 3.436 ± 1.336
4.009PheLeu: 4.009 ± 1.033
1.718PheMet: 1.718 ± 1.338
2.864PheAsn: 2.864 ± 0.984
2.864PhePro: 2.864 ± 0.651
2.291PheGln: 2.291 ± 0.595
4.009PheArg: 4.009 ± 1.195
2.864PheSer: 2.864 ± 0.962
4.009PheThr: 4.009 ± 1.433
2.864PheVal: 2.864 ± 1.424
0.0PheTrp: 0.0 ± 0.0
4.582PheTyr: 4.582 ± 1.323
0.0PheXaa: 0.0 ± 0.0
Gly
4.009GlyAla: 4.009 ± 1.273
0.573GlyCys: 0.573 ± 0.381
1.718GlyAsp: 1.718 ± 1.274
2.291GlyGlu: 2.291 ± 1.497
4.009GlyPhe: 4.009 ± 1.643
2.864GlyGly: 2.864 ± 1.776
1.145GlyHis: 1.145 ± 0.68
5.727GlyIle: 5.727 ± 2.129
3.436GlyLys: 3.436 ± 1.089
6.873GlyLeu: 6.873 ± 2.019
0.0GlyMet: 0.0 ± 0.0
1.145GlyAsn: 1.145 ± 0.763
0.0GlyPro: 0.0 ± 0.0
0.573GlyGln: 0.573 ± 0.48
1.718GlyArg: 1.718 ± 0.474
8.018GlySer: 8.018 ± 1.896
2.864GlyThr: 2.864 ± 1.444
1.718GlyVal: 1.718 ± 0.686
0.573GlyTrp: 0.573 ± 0.381
4.582GlyTyr: 4.582 ± 0.867
0.0GlyXaa: 0.0 ± 0.0
His
2.864HisAla: 2.864 ± 0.916
0.0HisCys: 0.0 ± 0.0
0.573HisAsp: 0.573 ± 0.724
0.573HisGlu: 0.573 ± 0.69
0.573HisPhe: 0.573 ± 0.604
1.718HisGly: 1.718 ± 1.338
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
0.0HisLys: 0.0 ± 0.0
1.145HisLeu: 1.145 ± 0.453
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
0.573HisPro: 0.573 ± 0.678
0.0HisGln: 0.0 ± 0.0
1.145HisArg: 1.145 ± 0.68
2.864HisSer: 2.864 ± 1.305
1.145HisThr: 1.145 ± 0.763
0.0HisVal: 0.0 ± 0.0
0.573HisTrp: 0.573 ± 0.549
1.718HisTyr: 1.718 ± 1.541
0.0HisXaa: 0.0 ± 0.0
Ile
5.155IleAla: 5.155 ± 1.668
0.0IleCys: 0.0 ± 0.0
2.291IleAsp: 2.291 ± 2.044
2.864IleGlu: 2.864 ± 1.76
2.291IlePhe: 2.291 ± 0.779
2.291IleGly: 2.291 ± 1.146
1.718IleHis: 1.718 ± 0.686
0.573IleIle: 0.573 ± 0.381
1.145IleLys: 1.145 ± 0.863
4.009IleLeu: 4.009 ± 1.33
2.291IleMet: 2.291 ± 1.398
2.291IleAsn: 2.291 ± 0.864
4.009IlePro: 4.009 ± 1.772
0.573IleGln: 0.573 ± 0.48
3.436IleArg: 3.436 ± 1.358
5.727IleSer: 5.727 ± 1.922
1.145IleThr: 1.145 ± 0.68
2.291IleVal: 2.291 ± 0.99
0.573IleTrp: 0.573 ± 0.381
3.436IleTyr: 3.436 ± 1.715
0.0IleXaa: 0.0 ± 0.0
Lys
2.864LysAla: 2.864 ± 1.203
0.0LysCys: 0.0 ± 0.0
2.864LysAsp: 2.864 ± 1.435
2.291LysGlu: 2.291 ± 0.668
1.145LysPhe: 1.145 ± 0.788
2.864LysGly: 2.864 ± 0.815
0.573LysHis: 0.573 ± 0.724
0.573LysIle: 0.573 ± 0.678
1.145LysLys: 1.145 ± 0.95
4.009LysLeu: 4.009 ± 2.058
1.145LysMet: 1.145 ± 0.841
2.864LysAsn: 2.864 ± 1.532
0.573LysPro: 0.573 ± 0.678
1.145LysGln: 1.145 ± 0.846
4.009LysArg: 4.009 ± 2.177
2.864LysSer: 2.864 ± 1.373
2.864LysThr: 2.864 ± 0.756
4.009LysVal: 4.009 ± 0.821
0.0LysTrp: 0.0 ± 0.0
1.145LysTyr: 1.145 ± 1.098
0.0LysXaa: 0.0 ± 0.0
Leu
6.873LeuAla: 6.873 ± 2.092
0.573LeuCys: 0.573 ± 0.678
6.873LeuAsp: 6.873 ± 1.69
4.582LeuGlu: 4.582 ± 0.819
5.155LeuPhe: 5.155 ± 2.152
5.155LeuGly: 5.155 ± 1.929
1.718LeuHis: 1.718 ± 0.837
3.436LeuIle: 3.436 ± 1.791
5.727LeuLys: 5.727 ± 1.936
3.436LeuLeu: 3.436 ± 1.009
1.718LeuMet: 1.718 ± 0.852
2.864LeuAsn: 2.864 ± 1.444
6.873LeuPro: 6.873 ± 2.25
1.718LeuGln: 1.718 ± 1.144
6.873LeuArg: 6.873 ± 1.209
10.882LeuSer: 10.882 ± 1.973
7.446LeuThr: 7.446 ± 1.267
5.727LeuVal: 5.727 ± 1.058
1.145LeuTrp: 1.145 ± 0.763
4.582LeuTyr: 4.582 ± 1.336
0.0LeuXaa: 0.0 ± 0.0
Met
1.718MetAla: 1.718 ± 0.729
0.573MetCys: 0.573 ± 0.711
2.291MetAsp: 2.291 ± 0.595
1.145MetGlu: 1.145 ± 0.863
1.145MetPhe: 1.145 ± 0.622
1.718MetGly: 1.718 ± 0.733
0.0MetHis: 0.0 ± 0.0
0.573MetIle: 0.573 ± 0.604
1.145MetLys: 1.145 ± 1.09
4.582MetLeu: 4.582 ± 1.444
1.718MetMet: 1.718 ± 0.674
1.718MetAsn: 1.718 ± 0.686
1.145MetPro: 1.145 ± 0.453
1.718MetGln: 1.718 ± 1.441
1.718MetArg: 1.718 ± 0.782
2.864MetSer: 2.864 ± 0.747
2.291MetThr: 2.291 ± 1.497
0.0MetVal: 0.0 ± 0.0
0.573MetTrp: 0.573 ± 0.381
0.573MetTyr: 0.573 ± 0.381
0.0MetXaa: 0.0 ± 0.0
Asn
4.009AsnAla: 4.009 ± 1.37
0.0AsnCys: 0.0 ± 0.0
2.864AsnAsp: 2.864 ± 1.444
0.0AsnGlu: 0.0 ± 0.0
1.718AsnPhe: 1.718 ± 0.845
2.291AsnGly: 2.291 ± 1.565
0.573AsnHis: 0.573 ± 0.69
2.291AsnIle: 2.291 ± 0.906
2.864AsnLys: 2.864 ± 0.88
5.155AsnLeu: 5.155 ± 1.284
1.718AsnMet: 1.718 ± 0.782
2.291AsnAsn: 2.291 ± 0.906
2.864AsnPro: 2.864 ± 0.963
3.436AsnGln: 3.436 ± 0.716
2.291AsnArg: 2.291 ± 1.567
1.145AsnSer: 1.145 ± 0.763
2.864AsnThr: 2.864 ± 1.068
0.0AsnVal: 0.0 ± 0.0
0.0AsnTrp: 0.0 ± 0.0
3.436AsnTyr: 3.436 ± 1.003
0.0AsnXaa: 0.0 ± 0.0
Pro
0.573ProAla: 0.573 ± 0.381
1.145ProCys: 1.145 ± 1.038
3.436ProAsp: 3.436 ± 1.427
2.291ProGlu: 2.291 ± 1.595
3.436ProPhe: 3.436 ± 0.914
1.145ProGly: 1.145 ± 0.961
0.573ProHis: 0.573 ± 0.48
3.436ProIle: 3.436 ± 1.634
1.145ProLys: 1.145 ± 0.846
8.018ProLeu: 8.018 ± 1.273
0.573ProMet: 0.573 ± 0.381
1.718ProAsn: 1.718 ± 0.942
0.573ProPro: 0.573 ± 0.678
2.291ProGln: 2.291 ± 0.906
2.291ProArg: 2.291 ± 0.888
6.873ProSer: 6.873 ± 2.759
4.009ProThr: 4.009 ± 1.828
1.718ProVal: 1.718 ± 0.734
0.0ProTrp: 0.0 ± 0.0
2.291ProTyr: 2.291 ± 1.525
0.0ProXaa: 0.0 ± 0.0
Gln
3.436GlnAla: 3.436 ± 2.249
0.0GlnCys: 0.0 ± 0.0
1.718GlnAsp: 1.718 ± 0.686
1.718GlnGlu: 1.718 ± 1.441
2.864GlnPhe: 2.864 ± 0.747
0.573GlnGly: 0.573 ± 0.381
0.0GlnHis: 0.0 ± 0.0
1.718GlnIle: 1.718 ± 0.686
1.145GlnLys: 1.145 ± 0.961
0.573GlnLeu: 0.573 ± 0.48
1.718GlnMet: 1.718 ± 0.474
1.718GlnAsn: 1.718 ± 0.782
1.145GlnPro: 1.145 ± 0.763
5.155GlnGln: 5.155 ± 3.68
5.727GlnArg: 5.727 ± 1.813
4.582GlnSer: 4.582 ± 1.476
4.009GlnThr: 4.009 ± 1.366
1.718GlnVal: 1.718 ± 0.856
0.573GlnTrp: 0.573 ± 0.48
0.573GlnTyr: 0.573 ± 0.48
0.0GlnXaa: 0.0 ± 0.0
Arg
5.155ArgAla: 5.155 ± 1.012
1.718ArgCys: 1.718 ± 1.146
4.009ArgAsp: 4.009 ± 1.193
4.009ArgGlu: 4.009 ± 1.398
3.436ArgPhe: 3.436 ± 1.866
2.864ArgGly: 2.864 ± 1.358
0.0ArgHis: 0.0 ± 0.0
2.864ArgIle: 2.864 ± 1.122
1.718ArgLys: 1.718 ± 1.501
5.727ArgLeu: 5.727 ± 1.528
3.436ArgMet: 3.436 ± 1.025
4.009ArgAsn: 4.009 ± 1.284
3.436ArgPro: 3.436 ± 0.975
2.864ArgGln: 2.864 ± 1.776
3.436ArgArg: 3.436 ± 0.973
6.873ArgSer: 6.873 ± 2.113
0.573ArgThr: 0.573 ± 0.48
1.718ArgVal: 1.718 ± 1.237
1.145ArgTrp: 1.145 ± 0.453
3.436ArgTyr: 3.436 ± 0.832
0.0ArgXaa: 0.0 ± 0.0
Ser
6.873SerAla: 6.873 ± 2.264
1.145SerCys: 1.145 ± 0.558
6.3SerAsp: 6.3 ± 1.157
6.3SerGlu: 6.3 ± 2.057
5.727SerPhe: 5.727 ± 1.554
8.591SerGly: 8.591 ± 2.624
3.436SerHis: 3.436 ± 0.975
5.727SerIle: 5.727 ± 1.297
0.573SerLys: 0.573 ± 0.381
5.155SerLeu: 5.155 ± 1.501
4.009SerMet: 4.009 ± 1.836
4.582SerAsn: 4.582 ± 1.729
5.155SerPro: 5.155 ± 2.78
2.864SerGln: 2.864 ± 1.098
5.727SerArg: 5.727 ± 0.769
14.318SerSer: 14.318 ± 3.297
5.727SerThr: 5.727 ± 1.059
4.582SerVal: 4.582 ± 2.38
1.145SerTrp: 1.145 ± 0.948
4.009SerTyr: 4.009 ± 0.956
0.0SerXaa: 0.0 ± 0.0
Thr
5.727ThrAla: 5.727 ± 1.524
1.145ThrCys: 1.145 ± 0.748
2.291ThrAsp: 2.291 ± 1.311
0.573ThrGlu: 0.573 ± 0.711
5.727ThrPhe: 5.727 ± 2.063
4.582ThrGly: 4.582 ± 1.201
0.0ThrHis: 0.0 ± 0.0
3.436ThrIle: 3.436 ± 0.982
1.145ThrLys: 1.145 ± 0.453
4.009ThrLeu: 4.009 ± 1.258
1.145ThrMet: 1.145 ± 0.696
2.291ThrAsn: 2.291 ± 0.881
2.864ThrPro: 2.864 ± 1.561
4.009ThrGln: 4.009 ± 1.717
2.864ThrArg: 2.864 ± 1.418
6.3ThrSer: 6.3 ± 1.664
4.009ThrThr: 4.009 ± 2.107
3.436ThrVal: 3.436 ± 0.696
0.573ThrTrp: 0.573 ± 0.381
3.436ThrTyr: 3.436 ± 1.06
0.0ThrXaa: 0.0 ± 0.0
Val
3.436ValAla: 3.436 ± 1.097
1.145ValCys: 1.145 ± 1.09
5.155ValAsp: 5.155 ± 1.61
2.864ValGlu: 2.864 ± 1.893
1.718ValPhe: 1.718 ± 0.978
2.864ValGly: 2.864 ± 1.254
0.573ValHis: 0.573 ± 0.678
1.145ValIle: 1.145 ± 0.453
1.718ValLys: 1.718 ± 0.783
4.582ValLeu: 4.582 ± 2.153
0.573ValMet: 0.573 ± 0.693
0.0ValAsn: 0.0 ± 0.0
4.582ValPro: 4.582 ± 1.729
1.145ValGln: 1.145 ± 0.674
2.291ValArg: 2.291 ± 1.215
6.873ValSer: 6.873 ± 1.344
1.718ValThr: 1.718 ± 1.144
3.436ValVal: 3.436 ± 1.335
0.573ValTrp: 0.573 ± 0.711
0.573ValTyr: 0.573 ± 0.381
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.573TrpCys: 0.573 ± 0.711
0.0TrpAsp: 0.0 ± 0.0
0.573TrpGlu: 0.573 ± 0.69
0.573TrpPhe: 0.573 ± 0.381
0.573TrpGly: 0.573 ± 0.381
0.573TrpHis: 0.573 ± 0.711
0.573TrpIle: 0.573 ± 0.381
0.0TrpLys: 0.0 ± 0.0
1.718TrpLeu: 1.718 ± 1.07
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.573TrpPro: 0.573 ± 0.381
0.0TrpGln: 0.0 ± 0.0
2.291TrpArg: 2.291 ± 0.772
0.573TrpSer: 0.573 ± 0.381
0.573TrpThr: 0.573 ± 0.381
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.864TyrAla: 2.864 ± 1.389
1.145TyrCys: 1.145 ± 0.86
4.582TyrAsp: 4.582 ± 2.206
1.145TyrGlu: 1.145 ± 0.863
4.009TyrPhe: 4.009 ± 1.367
2.864TyrGly: 2.864 ± 1.023
1.718TyrHis: 1.718 ± 0.733
2.291TyrIle: 2.291 ± 1.146
1.145TyrLys: 1.145 ± 0.902
6.3TyrLeu: 6.3 ± 2.029
1.718TyrMet: 1.718 ± 0.667
1.718TyrAsn: 1.718 ± 0.871
1.145TyrPro: 1.145 ± 0.95
4.582TyrGln: 4.582 ± 1.294
1.718TyrArg: 1.718 ± 0.474
5.155TyrSer: 5.155 ± 1.929
2.291TyrThr: 2.291 ± 0.864
3.436TyrVal: 3.436 ± 1.528
0.573TyrTrp: 0.573 ± 0.381
1.718TyrTyr: 1.718 ± 0.782
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 8 proteins (1747 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski