Amino acid dipepetide frequency for Microplitis demolitor bracovirus (isolate Webb) (MdBV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
1.767AlaAla: 1.767 ± 0.422
0.883AlaCys: 0.883 ± 0.315
2.749AlaAsp: 2.749 ± 0.494
3.73AlaGlu: 3.73 ± 0.717
2.356AlaPhe: 2.356 ± 0.426
1.767AlaGly: 1.767 ± 0.528
0.491AlaHis: 0.491 ± 0.225
4.025AlaIle: 4.025 ± 0.743
2.65AlaLys: 2.65 ± 0.558
3.534AlaLeu: 3.534 ± 0.581
0.393AlaMet: 0.393 ± 0.181
3.828AlaAsn: 3.828 ± 0.693
1.08AlaPro: 1.08 ± 0.34
2.454AlaGln: 2.454 ± 0.703
2.061AlaArg: 2.061 ± 0.679
4.221AlaSer: 4.221 ± 0.718
3.043AlaThr: 3.043 ± 0.656
3.338AlaVal: 3.338 ± 0.453
0.785AlaTrp: 0.785 ± 0.259
2.454AlaTyr: 2.454 ± 0.541
0.0AlaXaa: 0.0 ± 0.0
Cys
0.982CysAla: 0.982 ± 0.348
0.294CysCys: 0.294 ± 0.175
0.982CysAsp: 0.982 ± 0.355
1.669CysGlu: 1.669 ± 0.461
1.178CysPhe: 1.178 ± 0.327
0.687CysGly: 0.687 ± 0.25
0.687CysHis: 0.687 ± 0.243
2.454CysIle: 2.454 ± 0.497
1.08CysLys: 1.08 ± 0.378
1.963CysLeu: 1.963 ± 0.442
0.589CysMet: 0.589 ± 0.236
1.571CysAsn: 1.571 ± 0.396
0.393CysPro: 0.393 ± 0.197
1.276CysGln: 1.276 ± 0.335
2.16CysArg: 2.16 ± 0.545
2.356CysSer: 2.356 ± 0.488
1.472CysThr: 1.472 ± 0.274
1.767CysVal: 1.767 ± 0.383
0.982CysTrp: 0.982 ± 0.304
1.472CysTyr: 1.472 ± 0.323
0.0CysXaa: 0.0 ± 0.0
Asp
1.374AspAla: 1.374 ± 0.39
1.178AspCys: 1.178 ± 0.335
1.963AspAsp: 1.963 ± 0.459
5.694AspGlu: 5.694 ± 1.016
2.945AspPhe: 2.945 ± 0.576
4.025AspGly: 4.025 ± 0.716
1.276AspHis: 1.276 ± 0.404
3.828AspIle: 3.828 ± 0.575
2.16AspLys: 2.16 ± 0.501
5.301AspLeu: 5.301 ± 0.825
0.785AspMet: 0.785 ± 0.246
3.141AspAsn: 3.141 ± 0.565
1.08AspPro: 1.08 ± 0.289
1.963AspGln: 1.963 ± 0.499
1.472AspArg: 1.472 ± 0.586
5.792AspSer: 5.792 ± 0.742
2.061AspThr: 2.061 ± 0.461
2.356AspVal: 2.356 ± 0.433
0.589AspTrp: 0.589 ± 0.239
2.65AspTyr: 2.65 ± 0.444
0.0AspXaa: 0.0 ± 0.0
Glu
2.258GluAla: 2.258 ± 0.406
1.374GluCys: 1.374 ± 0.423
5.301GluAsp: 5.301 ± 0.833
5.694GluGlu: 5.694 ± 0.758
1.767GluPhe: 1.767 ± 0.471
3.632GluGly: 3.632 ± 0.496
2.749GluHis: 2.749 ± 0.52
5.595GluIle: 5.595 ± 0.922
4.712GluLys: 4.712 ± 0.741
4.908GluLeu: 4.908 ± 0.952
1.276GluMet: 1.276 ± 0.308
7.264GluAsn: 7.264 ± 1.175
1.276GluPro: 1.276 ± 0.376
1.472GluGln: 1.472 ± 0.394
3.73GluArg: 3.73 ± 0.792
3.239GluSer: 3.239 ± 0.71
7.068GluThr: 7.068 ± 1.697
2.356GluVal: 2.356 ± 0.557
1.472GluTrp: 1.472 ± 0.326
3.239GluTyr: 3.239 ± 0.676
0.0GluXaa: 0.0 ± 0.0
Phe
1.374PheAla: 1.374 ± 0.4
2.16PheCys: 2.16 ± 0.469
1.08PheAsp: 1.08 ± 0.332
1.374PheGlu: 1.374 ± 0.361
2.258PhePhe: 2.258 ± 0.498
3.73PheGly: 3.73 ± 0.612
0.883PheHis: 0.883 ± 0.298
3.043PheIle: 3.043 ± 0.516
2.356PheLys: 2.356 ± 0.528
3.239PheLeu: 3.239 ± 0.483
1.276PheMet: 1.276 ± 0.31
3.141PheAsn: 3.141 ± 0.716
1.08PhePro: 1.08 ± 0.341
1.571PheGln: 1.571 ± 0.367
1.669PheArg: 1.669 ± 0.342
3.239PheSer: 3.239 ± 0.552
1.571PheThr: 1.571 ± 0.308
2.258PheVal: 2.258 ± 0.538
1.767PheTrp: 1.767 ± 0.455
0.785PheTyr: 0.785 ± 0.262
0.0PheXaa: 0.0 ± 0.0
Gly
2.945GlyAla: 2.945 ± 0.664
0.589GlyCys: 0.589 ± 0.213
2.454GlyAsp: 2.454 ± 0.604
2.749GlyGlu: 2.749 ± 0.617
1.767GlyPhe: 1.767 ± 0.438
1.374GlyGly: 1.374 ± 0.347
0.393GlyHis: 0.393 ± 0.207
4.81GlyIle: 4.81 ± 1.125
3.043GlyLys: 3.043 ± 0.651
1.571GlyLeu: 1.571 ± 0.376
0.883GlyMet: 0.883 ± 0.261
2.552GlyAsn: 2.552 ± 0.503
1.669GlyPro: 1.669 ± 0.358
1.767GlyGln: 1.767 ± 0.627
1.963GlyArg: 1.963 ± 0.439
2.847GlySer: 2.847 ± 0.489
3.338GlyThr: 3.338 ± 0.601
2.16GlyVal: 2.16 ± 0.604
0.785GlyTrp: 0.785 ± 0.253
1.669GlyTyr: 1.669 ± 0.282
0.0GlyXaa: 0.0 ± 0.0
His
1.08HisAla: 1.08 ± 0.313
0.883HisCys: 0.883 ± 0.251
1.472HisAsp: 1.472 ± 0.379
1.865HisGlu: 1.865 ± 0.433
1.767HisPhe: 1.767 ± 0.386
0.883HisGly: 0.883 ± 0.316
1.374HisHis: 1.374 ± 0.322
2.945HisIle: 2.945 ± 0.602
1.08HisLys: 1.08 ± 0.341
1.178HisLeu: 1.178 ± 0.352
0.491HisMet: 0.491 ± 0.253
1.178HisAsn: 1.178 ± 0.353
0.883HisPro: 0.883 ± 0.276
0.785HisGln: 0.785 ± 0.257
1.669HisArg: 1.669 ± 0.373
2.16HisSer: 2.16 ± 0.526
2.061HisThr: 2.061 ± 0.449
0.785HisVal: 0.785 ± 0.281
0.491HisTrp: 0.491 ± 0.192
1.276HisTyr: 1.276 ± 0.335
0.0HisXaa: 0.0 ± 0.0
Ile
4.319IleAla: 4.319 ± 0.735
2.258IleCys: 2.258 ± 0.383
3.436IleAsp: 3.436 ± 0.647
4.123IleGlu: 4.123 ± 0.546
2.356IlePhe: 2.356 ± 0.462
1.374IleGly: 1.374 ± 0.399
2.16IleHis: 2.16 ± 0.498
7.46IleIle: 7.46 ± 0.975
3.534IleLys: 3.534 ± 0.679
6.381IleLeu: 6.381 ± 0.756
3.239IleMet: 3.239 ± 0.591
7.657IleAsn: 7.657 ± 1.077
2.454IlePro: 2.454 ± 0.456
1.865IleGln: 1.865 ± 0.54
3.828IleArg: 3.828 ± 0.516
5.203IleSer: 5.203 ± 1.012
4.123IleThr: 4.123 ± 0.727
6.086IleVal: 6.086 ± 0.633
0.294IleTrp: 0.294 ± 0.171
1.472IleTyr: 1.472 ± 0.353
0.0IleXaa: 0.0 ± 0.0
Lys
1.178LysAla: 1.178 ± 0.365
0.982LysCys: 0.982 ± 0.298
2.847LysAsp: 2.847 ± 0.577
4.516LysGlu: 4.516 ± 0.893
4.221LysPhe: 4.221 ± 0.752
2.552LysGly: 2.552 ± 0.424
0.687LysHis: 0.687 ± 0.227
5.694LysIle: 5.694 ± 0.684
6.97LysLys: 6.97 ± 0.926
5.89LysLeu: 5.89 ± 0.811
2.749LysMet: 2.749 ± 0.638
5.105LysAsn: 5.105 ± 0.645
4.614LysPro: 4.614 ± 1.297
1.865LysGln: 1.865 ± 0.425
3.141LysArg: 3.141 ± 0.633
6.086LysSer: 6.086 ± 0.875
5.595LysThr: 5.595 ± 0.789
2.847LysVal: 2.847 ± 0.567
0.687LysTrp: 0.687 ± 0.369
2.258LysTyr: 2.258 ± 0.535
0.098LysXaa: 0.098 ± 0.106
Leu
3.534LeuAla: 3.534 ± 0.548
2.945LeuCys: 2.945 ± 0.561
4.614LeuAsp: 4.614 ± 0.876
6.675LeuGlu: 6.675 ± 1.002
2.749LeuPhe: 2.749 ± 0.5
1.767LeuGly: 1.767 ± 0.694
3.436LeuHis: 3.436 ± 0.626
4.319LeuIle: 4.319 ± 0.635
6.283LeuLys: 6.283 ± 0.686
8.54LeuLeu: 8.54 ± 1.031
2.061LeuMet: 2.061 ± 0.583
5.694LeuAsn: 5.694 ± 1.04
2.061LeuPro: 2.061 ± 0.434
3.239LeuGln: 3.239 ± 0.559
3.828LeuArg: 3.828 ± 0.617
4.516LeuSer: 4.516 ± 0.66
6.675LeuThr: 6.675 ± 1.082
5.105LeuVal: 5.105 ± 0.946
0.785LeuTrp: 0.785 ± 0.272
1.767LeuTyr: 1.767 ± 0.425
0.098LeuXaa: 0.098 ± 0.106
Met
2.552MetAla: 2.552 ± 0.563
0.294MetCys: 0.294 ± 0.145
0.883MetAsp: 0.883 ± 0.257
2.356MetGlu: 2.356 ± 0.473
0.196MetPhe: 0.196 ± 0.13
0.785MetGly: 0.785 ± 0.254
0.491MetHis: 0.491 ± 0.232
1.08MetIle: 1.08 ± 0.276
2.258MetLys: 2.258 ± 0.41
1.963MetLeu: 1.963 ± 0.456
1.963MetMet: 1.963 ± 0.603
1.276MetAsn: 1.276 ± 0.372
1.08MetPro: 1.08 ± 0.304
0.687MetGln: 0.687 ± 0.26
2.061MetArg: 2.061 ± 0.479
2.454MetSer: 2.454 ± 0.465
0.982MetThr: 0.982 ± 0.269
1.669MetVal: 1.669 ± 0.401
0.196MetTrp: 0.196 ± 0.15
0.589MetTyr: 0.589 ± 0.213
0.0MetXaa: 0.0 ± 0.0
Asn
2.356AsnAla: 2.356 ± 0.471
1.178AsnCys: 1.178 ± 0.391
4.417AsnAsp: 4.417 ± 0.721
4.614AsnGlu: 4.614 ± 1.003
2.945AsnPhe: 2.945 ± 0.632
4.319AsnGly: 4.319 ± 0.867
1.08AsnHis: 1.08 ± 0.364
4.221AsnIle: 4.221 ± 0.511
5.203AsnLys: 5.203 ± 0.798
5.497AsnLeu: 5.497 ± 0.899
1.08AsnMet: 1.08 ± 0.35
4.417AsnAsn: 4.417 ± 0.807
1.571AsnPro: 1.571 ± 0.453
2.454AsnGln: 2.454 ± 0.539
3.632AsnArg: 3.632 ± 0.679
9.326AsnSer: 9.326 ± 1.832
4.81AsnThr: 4.81 ± 1.147
3.338AsnVal: 3.338 ± 0.52
0.196AsnTrp: 0.196 ± 0.139
3.73AsnTyr: 3.73 ± 0.708
0.0AsnXaa: 0.0 ± 0.0
Pro
2.454ProAla: 2.454 ± 0.701
0.883ProCys: 0.883 ± 0.274
1.767ProAsp: 1.767 ± 0.404
3.927ProGlu: 3.927 ± 0.857
0.491ProPhe: 0.491 ± 0.233
1.865ProGly: 1.865 ± 0.448
0.883ProHis: 0.883 ± 0.297
3.73ProIle: 3.73 ± 0.612
1.767ProLys: 1.767 ± 0.356
3.239ProLeu: 3.239 ± 0.621
0.982ProMet: 0.982 ± 0.285
1.963ProAsn: 1.963 ± 0.463
1.08ProPro: 1.08 ± 0.31
1.178ProGln: 1.178 ± 0.288
0.589ProArg: 0.589 ± 0.238
2.356ProSer: 2.356 ± 0.526
2.16ProThr: 2.16 ± 0.475
1.472ProVal: 1.472 ± 0.457
0.294ProTrp: 0.294 ± 0.172
1.178ProTyr: 1.178 ± 0.295
0.0ProXaa: 0.0 ± 0.0
Gln
2.552GlnAla: 2.552 ± 0.639
1.08GlnCys: 1.08 ± 0.335
0.982GlnAsp: 0.982 ± 0.268
3.436GlnGlu: 3.436 ± 0.517
1.374GlnPhe: 1.374 ± 0.374
1.08GlnGly: 1.08 ± 0.334
0.294GlnHis: 0.294 ± 0.156
1.669GlnIle: 1.669 ± 0.429
4.516GlnLys: 4.516 ± 1.02
2.847GlnLeu: 2.847 ± 0.606
0.785GlnMet: 0.785 ± 0.267
1.374GlnAsn: 1.374 ± 0.389
3.141GlnPro: 3.141 ± 0.914
2.061GlnGln: 2.061 ± 0.464
1.276GlnArg: 1.276 ± 0.372
2.65GlnSer: 2.65 ± 0.68
2.258GlnThr: 2.258 ± 0.454
1.669GlnVal: 1.669 ± 0.401
0.294GlnTrp: 0.294 ± 0.179
2.454GlnTyr: 2.454 ± 0.481
0.0GlnXaa: 0.0 ± 0.0
Arg
2.945ArgAla: 2.945 ± 0.506
0.883ArgCys: 0.883 ± 0.296
2.65ArgAsp: 2.65 ± 0.656
2.945ArgGlu: 2.945 ± 0.518
1.276ArgPhe: 1.276 ± 0.321
0.883ArgGly: 0.883 ± 0.301
2.16ArgHis: 2.16 ± 0.576
3.043ArgIle: 3.043 ± 0.54
7.46ArgLys: 7.46 ± 1.239
2.454ArgLeu: 2.454 ± 0.522
1.571ArgMet: 1.571 ± 0.494
4.417ArgAsn: 4.417 ± 0.649
1.08ArgPro: 1.08 ± 0.386
2.552ArgGln: 2.552 ± 0.57
2.552ArgArg: 2.552 ± 0.675
3.141ArgSer: 3.141 ± 0.713
2.454ArgThr: 2.454 ± 0.449
2.356ArgVal: 2.356 ± 0.577
0.294ArgTrp: 0.294 ± 0.183
2.454ArgTyr: 2.454 ± 0.543
0.098ArgXaa: 0.098 ± 0.109
Ser
5.694SerAla: 5.694 ± 0.913
2.16SerCys: 2.16 ± 0.466
4.417SerAsp: 4.417 ± 0.821
5.203SerGlu: 5.203 ± 0.728
3.043SerPhe: 3.043 ± 0.689
3.043SerGly: 3.043 ± 0.676
3.141SerHis: 3.141 ± 0.507
4.123SerIle: 4.123 ± 0.537
5.203SerLys: 5.203 ± 0.618
4.81SerLeu: 4.81 ± 0.657
1.571SerMet: 1.571 ± 0.369
5.006SerAsn: 5.006 ± 0.774
2.945SerPro: 2.945 ± 0.711
3.927SerGln: 3.927 ± 0.664
4.614SerArg: 4.614 ± 0.943
9.718SerSer: 9.718 ± 1.397
6.479SerThr: 6.479 ± 1.537
3.534SerVal: 3.534 ± 0.996
1.865SerTrp: 1.865 ± 0.622
1.276SerTyr: 1.276 ± 0.338
0.0SerXaa: 0.0 ± 0.0
Thr
2.454ThrAla: 2.454 ± 0.596
2.258ThrCys: 2.258 ± 0.404
3.632ThrAsp: 3.632 ± 0.786
3.632ThrGlu: 3.632 ± 0.57
2.061ThrPhe: 2.061 ± 0.337
4.123ThrGly: 4.123 ± 0.638
1.276ThrHis: 1.276 ± 0.316
4.025ThrIle: 4.025 ± 0.693
4.025ThrLys: 4.025 ± 0.693
7.166ThrLeu: 7.166 ± 0.776
0.982ThrMet: 0.982 ± 0.261
3.436ThrAsn: 3.436 ± 0.673
2.258ThrPro: 2.258 ± 0.57
4.025ThrGln: 4.025 ± 0.907
4.712ThrArg: 4.712 ± 1.186
4.908ThrSer: 4.908 ± 0.753
4.123ThrThr: 4.123 ± 0.919
3.828ThrVal: 3.828 ± 0.679
0.785ThrTrp: 0.785 ± 0.259
2.356ThrTyr: 2.356 ± 0.553
0.0ThrXaa: 0.0 ± 0.0
Val
2.552ValAla: 2.552 ± 0.449
1.571ValCys: 1.571 ± 0.439
3.436ValAsp: 3.436 ± 0.641
2.65ValGlu: 2.65 ± 0.785
3.141ValPhe: 3.141 ± 0.832
1.472ValGly: 1.472 ± 0.29
1.669ValHis: 1.669 ± 0.392
3.73ValIle: 3.73 ± 0.644
3.141ValLys: 3.141 ± 0.405
5.105ValLeu: 5.105 ± 0.712
1.963ValMet: 1.963 ± 0.436
3.828ValAsn: 3.828 ± 0.637
2.552ValPro: 2.552 ± 0.482
0.687ValGln: 0.687 ± 0.307
2.749ValArg: 2.749 ± 0.589
5.006ValSer: 5.006 ± 0.593
3.338ValThr: 3.338 ± 0.756
3.141ValVal: 3.141 ± 0.542
0.785ValTrp: 0.785 ± 0.285
1.472ValTyr: 1.472 ± 0.366
0.0ValXaa: 0.0 ± 0.0
Trp
1.472TrpAla: 1.472 ± 0.571
0.687TrpCys: 0.687 ± 0.261
0.785TrpAsp: 0.785 ± 0.247
0.687TrpGlu: 0.687 ± 0.221
0.687TrpPhe: 0.687 ± 0.31
0.294TrpGly: 0.294 ± 0.17
0.098TrpHis: 0.098 ± 0.117
0.883TrpIle: 0.883 ± 0.302
1.276TrpLys: 1.276 ± 0.357
2.061TrpLeu: 2.061 ± 0.596
0.589TrpMet: 0.589 ± 0.209
0.687TrpAsn: 0.687 ± 0.234
1.08TrpPro: 1.08 ± 0.324
0.393TrpGln: 0.393 ± 0.176
0.785TrpArg: 0.785 ± 0.297
1.178TrpSer: 1.178 ± 0.316
0.294TrpThr: 0.294 ± 0.156
0.294TrpVal: 0.294 ± 0.15
0.0TrpTrp: 0.0 ± 0.0
0.687TrpTyr: 0.687 ± 0.234
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.767TyrAla: 1.767 ± 0.558
1.374TyrCys: 1.374 ± 0.35
1.767TyrAsp: 1.767 ± 0.446
2.847TyrGlu: 2.847 ± 0.481
1.276TyrPhe: 1.276 ± 0.277
1.669TyrGly: 1.669 ± 0.455
0.982TyrHis: 0.982 ± 0.273
2.945TyrIle: 2.945 ± 0.479
1.865TyrLys: 1.865 ± 0.443
3.043TyrLeu: 3.043 ± 0.519
0.491TyrMet: 0.491 ± 0.173
2.847TyrAsn: 2.847 ± 0.414
0.883TyrPro: 0.883 ± 0.288
1.571TyrGln: 1.571 ± 0.462
1.178TyrArg: 1.178 ± 0.274
1.374TyrSer: 1.374 ± 0.51
2.16TyrThr: 2.16 ± 0.444
3.632TyrVal: 3.632 ± 0.501
1.571TyrTrp: 1.571 ± 0.381
1.767TyrTyr: 1.767 ± 0.443
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.098XaaCys: 0.098 ± 0.106
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.098XaaHis: 0.098 ± 0.109
0.0XaaIle: 0.0 ± 0.0
0.098XaaLys: 0.098 ± 0.106
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 53 proteins (10188 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski