Amino acid dipepetide frequency for Meleagrid herpesvirus 1 (MeHV-1) (Turkey herpesvirus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.472AlaAla: 7.472 ± 0.658
1.965AlaCys: 1.965 ± 0.213
4.197AlaAsp: 4.197 ± 0.458
4.027AlaGlu: 4.027 ± 0.34
3.882AlaPhe: 3.882 ± 0.302
4.634AlaGly: 4.634 ± 0.478
1.601AlaHis: 1.601 ± 0.173
5.628AlaIle: 5.628 ± 0.377
2.572AlaLys: 2.572 ± 0.266
7.108AlaLeu: 7.108 ± 0.556
2.256AlaMet: 2.256 ± 0.21
2.669AlaAsn: 2.669 ± 0.255
3.396AlaPro: 3.396 ± 0.442
1.722AlaGln: 1.722 ± 0.189
5.531AlaArg: 5.531 ± 0.394
6.769AlaSer: 6.769 ± 0.428
4.658AlaThr: 4.658 ± 0.311
5.289AlaVal: 5.289 ± 0.427
0.97AlaTrp: 0.97 ± 0.146
2.596AlaTyr: 2.596 ± 0.235
0.0AlaXaa: 0.0 ± 0.0
Cys
1.674CysAla: 1.674 ± 0.245
0.679CysCys: 0.679 ± 0.163
1.528CysAsp: 1.528 ± 0.19
1.359CysGlu: 1.359 ± 0.154
1.043CysPhe: 1.043 ± 0.145
1.383CysGly: 1.383 ± 0.198
0.558CysHis: 0.558 ± 0.114
1.625CysIle: 1.625 ± 0.241
0.922CysLys: 0.922 ± 0.143
2.256CysLeu: 2.256 ± 0.229
1.019CysMet: 1.019 ± 0.18
1.334CysAsn: 1.334 ± 0.217
1.067CysPro: 1.067 ± 0.193
0.655CysGln: 0.655 ± 0.135
1.722CysArg: 1.722 ± 0.224
1.674CysSer: 1.674 ± 0.21
1.674CysThr: 1.674 ± 0.218
1.795CysVal: 1.795 ± 0.196
0.218CysTrp: 0.218 ± 0.074
0.655CysTyr: 0.655 ± 0.149
0.0CysXaa: 0.0 ± 0.0
Asp
5.022AspAla: 5.022 ± 0.391
1.286AspCys: 1.286 ± 0.182
2.984AspAsp: 2.984 ± 0.269
2.814AspGlu: 2.814 ± 0.217
1.82AspPhe: 1.82 ± 0.193
4.051AspGly: 4.051 ± 0.245
1.456AspHis: 1.456 ± 0.192
3.542AspIle: 3.542 ± 0.348
1.844AspLys: 1.844 ± 0.227
4.706AspLeu: 4.706 ± 0.389
1.577AspMet: 1.577 ± 0.248
2.038AspAsn: 2.038 ± 0.227
2.96AspPro: 2.96 ± 0.277
1.262AspGln: 1.262 ± 0.138
3.324AspArg: 3.324 ± 0.305
4.803AspSer: 4.803 ± 0.454
3.493AspThr: 3.493 ± 0.312
3.833AspVal: 3.833 ± 0.345
0.728AspTrp: 0.728 ± 0.13
1.941AspTyr: 1.941 ± 0.227
0.0AspXaa: 0.0 ± 0.0
Glu
3.857GluAla: 3.857 ± 0.403
1.601GluCys: 1.601 ± 0.221
2.887GluAsp: 2.887 ± 0.248
2.644GluGlu: 2.644 ± 0.227
1.577GluPhe: 1.577 ± 0.159
2.741GluGly: 2.741 ± 0.274
1.383GluHis: 1.383 ± 0.149
2.766GluIle: 2.766 ± 0.265
2.159GluLys: 2.159 ± 0.206
5.095GluLeu: 5.095 ± 0.476
1.456GluMet: 1.456 ± 0.206
2.596GluAsn: 2.596 ± 0.228
2.523GluPro: 2.523 ± 0.266
1.359GluGln: 1.359 ± 0.163
3.833GluArg: 3.833 ± 0.255
4.197GluSer: 4.197 ± 0.456
3.663GluThr: 3.663 ± 0.245
2.45GluVal: 2.45 ± 0.22
0.655GluTrp: 0.655 ± 0.118
2.256GluTyr: 2.256 ± 0.225
0.0GluXaa: 0.0 ± 0.0
Phe
2.935PheAla: 2.935 ± 0.238
0.873PheCys: 0.873 ± 0.164
2.353PheAsp: 2.353 ± 0.283
1.747PheGlu: 1.747 ± 0.207
1.965PhePhe: 1.965 ± 0.241
2.28PheGly: 2.28 ± 0.301
0.922PheHis: 0.922 ± 0.126
2.353PheIle: 2.353 ± 0.286
1.747PheLys: 1.747 ± 0.187
3.493PheLeu: 3.493 ± 0.363
1.262PheMet: 1.262 ± 0.178
1.747PheAsn: 1.747 ± 0.19
1.698PhePro: 1.698 ± 0.258
1.019PheGln: 1.019 ± 0.147
1.625PheArg: 1.625 ± 0.198
3.372PheSer: 3.372 ± 0.25
2.377PheThr: 2.377 ± 0.203
2.62PheVal: 2.62 ± 0.262
0.461PheTrp: 0.461 ± 0.103
1.65PheTyr: 1.65 ± 0.186
0.0PheXaa: 0.0 ± 0.0
Gly
4.076GlyAla: 4.076 ± 0.264
1.456GlyCys: 1.456 ± 0.204
3.688GlyAsp: 3.688 ± 0.286
3.105GlyGlu: 3.105 ± 0.263
1.917GlyPhe: 1.917 ± 0.206
4.1GlyGly: 4.1 ± 0.493
1.262GlyHis: 1.262 ± 0.211
3.299GlyIle: 3.299 ± 0.3
2.984GlyLys: 2.984 ± 0.347
5.192GlyLeu: 5.192 ± 0.33
1.795GlyMet: 1.795 ± 0.209
2.644GlyAsn: 2.644 ± 0.22
2.596GlyPro: 2.596 ± 0.385
1.844GlyGln: 1.844 ± 0.222
4.318GlyArg: 4.318 ± 0.351
5.143GlySer: 5.143 ± 0.406
4.076GlyThr: 4.076 ± 0.372
3.227GlyVal: 3.227 ± 0.295
0.801GlyTrp: 0.801 ± 0.143
2.111GlyTyr: 2.111 ± 0.308
0.0GlyXaa: 0.0 ± 0.0
His
2.377HisAla: 2.377 ± 0.211
0.34HisCys: 0.34 ± 0.102
1.431HisAsp: 1.431 ± 0.186
0.825HisGlu: 0.825 ± 0.127
1.043HisPhe: 1.043 ± 0.171
1.698HisGly: 1.698 ± 0.229
0.655HisHis: 0.655 ± 0.14
1.334HisIle: 1.334 ± 0.165
1.213HisLys: 1.213 ± 0.162
2.377HisLeu: 2.377 ± 0.177
0.509HisMet: 0.509 ± 0.107
0.995HisAsn: 0.995 ± 0.118
1.262HisPro: 1.262 ± 0.222
0.655HisGln: 0.655 ± 0.118
2.014HisArg: 2.014 ± 0.252
1.965HisSer: 1.965 ± 0.248
1.456HisThr: 1.456 ± 0.187
1.674HisVal: 1.674 ± 0.177
0.146HisTrp: 0.146 ± 0.052
0.607HisTyr: 0.607 ± 0.129
0.0HisXaa: 0.0 ± 0.0
Ile
4.682IleAla: 4.682 ± 0.322
1.65IleCys: 1.65 ± 0.24
3.566IleAsp: 3.566 ± 0.287
3.275IleGlu: 3.275 ± 0.325
2.256IlePhe: 2.256 ± 0.24
3.154IleGly: 3.154 ± 0.267
1.262IleHis: 1.262 ± 0.173
4.44IleIle: 4.44 ± 0.411
2.377IleLys: 2.377 ± 0.256
5.895IleLeu: 5.895 ± 0.422
1.092IleMet: 1.092 ± 0.167
2.693IleAsn: 2.693 ± 0.326
3.348IlePro: 3.348 ± 0.375
1.917IleGln: 1.917 ± 0.287
4.076IleArg: 4.076 ± 0.348
4.949IleSer: 4.949 ± 0.345
3.324IleThr: 3.324 ± 0.322
3.93IleVal: 3.93 ± 0.441
0.631IleTrp: 0.631 ± 0.13
2.499IleTyr: 2.499 ± 0.267
0.0IleXaa: 0.0 ± 0.0
Lys
2.547LysAla: 2.547 ± 0.252
1.116LysCys: 1.116 ± 0.138
1.844LysAsp: 1.844 ± 0.196
2.232LysGlu: 2.232 ± 0.244
1.65LysPhe: 1.65 ± 0.2
1.722LysGly: 1.722 ± 0.201
1.092LysHis: 1.092 ± 0.177
2.45LysIle: 2.45 ± 0.298
1.771LysLys: 1.771 ± 0.216
3.857LysLeu: 3.857 ± 0.349
1.067LysMet: 1.067 ± 0.167
2.086LysAsn: 2.086 ± 0.234
1.674LysPro: 1.674 ± 0.194
1.359LysGln: 1.359 ± 0.165
3.615LysArg: 3.615 ± 0.267
2.887LysSer: 2.887 ± 0.27
2.814LysThr: 2.814 ± 0.263
1.795LysVal: 1.795 ± 0.233
0.607LysTrp: 0.607 ± 0.137
1.941LysTyr: 1.941 ± 0.259
0.0LysXaa: 0.0 ± 0.0
Leu
7.23LeuAla: 7.23 ± 0.5
2.402LeuCys: 2.402 ± 0.232
4.561LeuAsp: 4.561 ± 0.457
5.434LeuGlu: 5.434 ± 0.314
4.197LeuPhe: 4.197 ± 0.356
4.925LeuGly: 4.925 ± 0.378
2.183LeuHis: 2.183 ± 0.244
4.755LeuIle: 4.755 ± 0.391
3.809LeuLys: 3.809 ± 0.4
9.631LeuLeu: 9.631 ± 0.585
2.644LeuMet: 2.644 ± 0.282
3.154LeuAsn: 3.154 ± 0.378
4.609LeuPro: 4.609 ± 0.444
2.984LeuGln: 2.984 ± 0.274
5.968LeuArg: 5.968 ± 0.393
7.812LeuSer: 7.812 ± 0.449
5.483LeuThr: 5.483 ± 0.292
5.483LeuVal: 5.483 ± 0.289
1.286LeuTrp: 1.286 ± 0.165
3.275LeuTyr: 3.275 ± 0.27
0.0LeuXaa: 0.0 ± 0.0
Met
2.45MetAla: 2.45 ± 0.201
0.582MetCys: 0.582 ± 0.112
1.625MetAsp: 1.625 ± 0.173
1.31MetGlu: 1.31 ± 0.18
0.873MetPhe: 0.873 ± 0.165
1.868MetGly: 1.868 ± 0.207
0.752MetHis: 0.752 ± 0.109
1.504MetIle: 1.504 ± 0.176
0.946MetLys: 0.946 ± 0.171
2.523MetLeu: 2.523 ± 0.257
0.582MetMet: 0.582 ± 0.123
1.067MetAsn: 1.067 ± 0.161
1.262MetPro: 1.262 ± 0.206
0.728MetGln: 0.728 ± 0.136
1.989MetArg: 1.989 ± 0.229
2.232MetSer: 2.232 ± 0.215
1.48MetThr: 1.48 ± 0.194
1.334MetVal: 1.334 ± 0.166
0.267MetTrp: 0.267 ± 0.081
1.067MetTyr: 1.067 ± 0.143
0.0MetXaa: 0.0 ± 0.0
Asn
2.911AsnAla: 2.911 ± 0.33
0.849AsnCys: 0.849 ± 0.15
1.989AsnAsp: 1.989 ± 0.219
1.868AsnGlu: 1.868 ± 0.183
1.504AsnPhe: 1.504 ± 0.232
2.669AsnGly: 2.669 ± 0.232
1.019AsnHis: 1.019 ± 0.18
3.033AsnIle: 3.033 ± 0.281
1.795AsnLys: 1.795 ± 0.227
3.445AsnLeu: 3.445 ± 0.288
1.504AsnMet: 1.504 ± 0.197
2.038AsnAsn: 2.038 ± 0.273
2.28AsnPro: 2.28 ± 0.544
0.801AsnGln: 0.801 ± 0.121
2.208AsnArg: 2.208 ± 0.209
3.809AsnSer: 3.809 ± 0.308
2.887AsnThr: 2.887 ± 0.292
3.59AsnVal: 3.59 ± 0.319
0.34AsnTrp: 0.34 ± 0.09
1.334AsnTyr: 1.334 ± 0.208
0.0AsnXaa: 0.0 ± 0.0
Pro
3.493ProAla: 3.493 ± 0.469
1.383ProCys: 1.383 ± 0.185
2.547ProAsp: 2.547 ± 0.258
2.935ProGlu: 2.935 ± 0.317
1.868ProPhe: 1.868 ± 0.228
2.935ProGly: 2.935 ± 0.451
1.528ProHis: 1.528 ± 0.248
3.251ProIle: 3.251 ± 0.261
1.625ProLys: 1.625 ± 0.227
4.246ProLeu: 4.246 ± 0.406
1.043ProMet: 1.043 ± 0.197
2.062ProAsn: 2.062 ± 0.526
4.634ProPro: 4.634 ± 0.706
1.043ProGln: 1.043 ± 0.184
3.663ProArg: 3.663 ± 0.447
5.167ProSer: 5.167 ± 0.511
4.148ProThr: 4.148 ± 0.269
3.008ProVal: 3.008 ± 0.369
0.437ProTrp: 0.437 ± 0.094
1.334ProTyr: 1.334 ± 0.15
0.0ProXaa: 0.0 ± 0.0
Gln
1.82GlnAla: 1.82 ± 0.179
0.849GlnCys: 0.849 ± 0.165
1.164GlnAsp: 1.164 ± 0.126
0.995GlnGlu: 0.995 ± 0.159
1.043GlnPhe: 1.043 ± 0.23
1.286GlnGly: 1.286 ± 0.178
0.801GlnHis: 0.801 ± 0.133
1.431GlnIle: 1.431 ± 0.192
1.359GlnLys: 1.359 ± 0.155
2.669GlnLeu: 2.669 ± 0.234
0.922GlnMet: 0.922 ± 0.166
0.898GlnAsn: 0.898 ± 0.134
1.213GlnPro: 1.213 ± 0.241
1.14GlnGln: 1.14 ± 0.14
1.82GlnArg: 1.82 ± 0.205
2.402GlnSer: 2.402 ± 0.251
2.062GlnThr: 2.062 ± 0.244
1.092GlnVal: 1.092 ± 0.172
0.146GlnTrp: 0.146 ± 0.06
1.164GlnTyr: 1.164 ± 0.172
0.0GlnXaa: 0.0 ± 0.0
Arg
5.07ArgAla: 5.07 ± 0.433
1.674ArgCys: 1.674 ± 0.208
3.954ArgAsp: 3.954 ± 0.331
3.105ArgGlu: 3.105 ± 0.329
2.596ArgPhe: 2.596 ± 0.253
3.979ArgGly: 3.979 ± 0.341
1.941ArgHis: 1.941 ± 0.231
3.299ArgIle: 3.299 ± 0.303
2.96ArgLys: 2.96 ± 0.284
6.308ArgLeu: 6.308 ± 0.354
1.722ArgMet: 1.722 ± 0.218
3.033ArgAsn: 3.033 ± 0.269
3.882ArgPro: 3.882 ± 0.486
1.771ArgGln: 1.771 ± 0.187
6.065ArgArg: 6.065 ± 0.585
5.24ArgSer: 5.24 ± 0.51
3.979ArgThr: 3.979 ± 0.327
3.688ArgVal: 3.688 ± 0.354
0.801ArgTrp: 0.801 ± 0.129
2.693ArgTyr: 2.693 ± 0.236
0.0ArgXaa: 0.0 ± 0.0
Ser
7.618SerAla: 7.618 ± 0.549
1.844SerCys: 1.844 ± 0.235
4.779SerAsp: 4.779 ± 0.314
5.58SerGlu: 5.58 ± 0.407
2.547SerPhe: 2.547 ± 0.275
5.871SerGly: 5.871 ± 0.602
2.062SerHis: 2.062 ± 0.228
4.828SerIle: 4.828 ± 0.39
3.227SerLys: 3.227 ± 0.356
7.23SerLeu: 7.23 ± 0.428
1.722SerMet: 1.722 ± 0.242
3.59SerAsn: 3.59 ± 0.297
4.925SerPro: 4.925 ± 0.899
2.232SerGln: 2.232 ± 0.216
5.822SerArg: 5.822 ± 0.474
8.224SerSer: 8.224 ± 1.011
5.968SerThr: 5.968 ± 0.391
4.634SerVal: 4.634 ± 0.364
0.752SerTrp: 0.752 ± 0.163
2.353SerTyr: 2.353 ± 0.259
0.0SerXaa: 0.0 ± 0.0
Thr
5.507ThrAla: 5.507 ± 0.436
1.456ThrCys: 1.456 ± 0.228
3.76ThrAsp: 3.76 ± 0.334
2.717ThrGlu: 2.717 ± 0.228
2.62ThrPhe: 2.62 ± 0.282
3.227ThrGly: 3.227 ± 0.258
1.674ThrHis: 1.674 ± 0.172
4.367ThrIle: 4.367 ± 0.33
2.28ThrLys: 2.28 ± 0.271
5.604ThrLeu: 5.604 ± 0.395
1.48ThrMet: 1.48 ± 0.188
2.644ThrAsn: 2.644 ± 0.299
3.518ThrPro: 3.518 ± 0.31
1.431ThrGln: 1.431 ± 0.171
3.712ThrArg: 3.712 ± 0.256
6.089ThrSer: 6.089 ± 0.459
4.221ThrThr: 4.221 ± 0.414
4.973ThrVal: 4.973 ± 0.268
0.849ThrTrp: 0.849 ± 0.192
2.208ThrTyr: 2.208 ± 0.263
0.0ThrXaa: 0.0 ± 0.0
Val
4.488ValAla: 4.488 ± 0.334
1.65ValCys: 1.65 ± 0.257
4.148ValAsp: 4.148 ± 0.251
3.251ValGlu: 3.251 ± 0.264
2.305ValPhe: 2.305 ± 0.217
3.882ValGly: 3.882 ± 0.262
1.334ValHis: 1.334 ± 0.161
4.003ValIle: 4.003 ± 0.325
2.28ValLys: 2.28 ± 0.206
5.968ValLeu: 5.968 ± 0.323
1.456ValMet: 1.456 ± 0.193
2.572ValAsn: 2.572 ± 0.261
3.493ValPro: 3.493 ± 0.323
1.262ValGln: 1.262 ± 0.155
3.615ValArg: 3.615 ± 0.262
5.337ValSer: 5.337 ± 0.429
3.372ValThr: 3.372 ± 0.265
3.469ValVal: 3.469 ± 0.276
0.558ValTrp: 0.558 ± 0.121
2.838ValTyr: 2.838 ± 0.287
0.0ValXaa: 0.0 ± 0.0
Trp
0.679TrpAla: 0.679 ± 0.132
0.267TrpCys: 0.267 ± 0.075
0.582TrpAsp: 0.582 ± 0.11
0.437TrpGlu: 0.437 ± 0.1
0.485TrpPhe: 0.485 ± 0.093
0.849TrpGly: 0.849 ± 0.119
0.34TrpHis: 0.34 ± 0.087
0.679TrpIle: 0.679 ± 0.149
0.825TrpLys: 0.825 ± 0.124
0.995TrpLeu: 0.995 ± 0.167
0.315TrpMet: 0.315 ± 0.082
0.509TrpAsn: 0.509 ± 0.106
0.485TrpPro: 0.485 ± 0.108
0.315TrpGln: 0.315 ± 0.082
0.776TrpArg: 0.776 ± 0.145
0.825TrpSer: 0.825 ± 0.16
0.873TrpThr: 0.873 ± 0.14
0.558TrpVal: 0.558 ± 0.105
0.121TrpTrp: 0.121 ± 0.054
0.243TrpTyr: 0.243 ± 0.065
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.033TyrAla: 3.033 ± 0.269
0.922TyrCys: 0.922 ± 0.146
1.892TyrAsp: 1.892 ± 0.238
2.062TyrGlu: 2.062 ± 0.203
1.31TyrPhe: 1.31 ± 0.209
2.377TyrGly: 2.377 ± 0.235
0.752TyrHis: 0.752 ± 0.132
2.426TyrIle: 2.426 ± 0.24
1.431TyrLys: 1.431 ± 0.16
3.227TyrLeu: 3.227 ± 0.315
0.995TyrMet: 0.995 ± 0.152
1.504TyrAsn: 1.504 ± 0.183
1.528TyrPro: 1.528 ± 0.188
0.776TyrGln: 0.776 ± 0.143
2.062TyrArg: 2.062 ± 0.21
2.911TyrSer: 2.911 ± 0.244
2.329TyrThr: 2.329 ± 0.268
2.838TyrVal: 2.838 ± 0.252
0.388TyrTrp: 0.388 ± 0.1
1.31TyrTyr: 1.31 ± 0.172
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 87 proteins (41221 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski