Amino acid dipepetide frequency for Macaca mulata papillomavirus 1 (Rhpv 1) (Rhesus papillomavirus type 1)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.377AlaAla: 6.377 ± 1.876
1.594AlaCys: 1.594 ± 0.899
3.986AlaAsp: 3.986 ± 0.824
2.391AlaGlu: 2.391 ± 0.914
2.391AlaPhe: 2.391 ± 1.101
7.174AlaGly: 7.174 ± 1.203
2.79AlaHis: 2.79 ± 0.853
1.993AlaIle: 1.993 ± 0.714
3.587AlaLys: 3.587 ± 1.408
5.978AlaLeu: 5.978 ± 1.154
1.594AlaMet: 1.594 ± 0.792
2.79AlaAsn: 2.79 ± 1.172
3.587AlaPro: 3.587 ± 1.61
1.993AlaGln: 1.993 ± 1.016
3.189AlaArg: 3.189 ± 0.625
5.58AlaSer: 5.58 ± 2.274
5.181AlaThr: 5.181 ± 1.208
3.587AlaVal: 3.587 ± 0.723
0.0AlaTrp: 0.0 ± 0.0
2.391AlaTyr: 2.391 ± 0.584
0.0AlaXaa: 0.0 ± 0.0
Cys
1.993CysAla: 1.993 ± 0.62
2.391CysCys: 2.391 ± 2.171
1.196CysAsp: 1.196 ± 0.791
0.797CysGlu: 0.797 ± 0.489
2.391CysPhe: 2.391 ± 2.076
2.79CysGly: 2.79 ± 1.289
0.0CysHis: 0.0 ± 0.0
1.196CysIle: 1.196 ± 0.677
2.391CysLys: 2.391 ± 1.307
3.986CysLeu: 3.986 ± 1.571
0.797CysMet: 0.797 ± 0.391
0.399CysAsn: 0.399 ± 0.513
3.189CysPro: 3.189 ± 1.33
0.797CysGln: 0.797 ± 0.519
0.797CysArg: 0.797 ± 0.693
1.196CysSer: 1.196 ± 0.753
1.594CysThr: 1.594 ± 0.692
2.79CysVal: 2.79 ± 0.742
1.196CysTrp: 1.196 ± 0.486
1.993CysTyr: 1.993 ± 1.337
0.0CysXaa: 0.0 ± 0.0
Asp
4.384AspAla: 4.384 ± 0.808
2.79AspCys: 2.79 ± 1.011
3.986AspAsp: 3.986 ± 2.086
1.993AspGlu: 1.993 ± 0.92
2.391AspPhe: 2.391 ± 0.606
3.587AspGly: 3.587 ± 1.056
1.196AspHis: 1.196 ± 0.48
2.391AspIle: 2.391 ± 1.172
1.196AspLys: 1.196 ± 0.791
5.978AspLeu: 5.978 ± 1.396
0.399AspMet: 0.399 ± 0.35
2.391AspAsn: 2.391 ± 1.024
3.587AspPro: 3.587 ± 1.274
2.391AspGln: 2.391 ± 0.727
1.993AspArg: 1.993 ± 1.338
4.783AspSer: 4.783 ± 1.454
3.986AspThr: 3.986 ± 1.189
4.384AspVal: 4.384 ± 2.146
1.594AspTrp: 1.594 ± 0.966
1.196AspTyr: 1.196 ± 0.689
0.0AspXaa: 0.0 ± 0.0
Glu
3.189GluAla: 3.189 ± 1.279
1.594GluCys: 1.594 ± 0.769
5.181GluAsp: 5.181 ± 1.808
3.587GluGlu: 3.587 ± 0.615
0.797GluPhe: 0.797 ± 0.391
1.993GluGly: 1.993 ± 0.961
0.797GluHis: 0.797 ± 0.443
1.993GluIle: 1.993 ± 0.754
2.391GluLys: 2.391 ± 0.75
4.783GluLeu: 4.783 ± 1.546
0.797GluMet: 0.797 ± 0.458
1.993GluAsn: 1.993 ± 0.582
2.79GluPro: 2.79 ± 0.986
1.594GluGln: 1.594 ± 0.596
1.594GluArg: 1.594 ± 0.721
2.79GluSer: 2.79 ± 1.238
2.79GluThr: 2.79 ± 1.758
5.181GluVal: 5.181 ± 1.007
1.196GluTrp: 1.196 ± 0.791
2.391GluTyr: 2.391 ± 0.75
0.0GluXaa: 0.0 ± 0.0
Phe
1.196PheAla: 1.196 ± 0.679
1.993PheCys: 1.993 ± 1.663
1.993PheAsp: 1.993 ± 0.624
0.797PheGlu: 0.797 ± 0.371
1.993PhePhe: 1.993 ± 0.54
2.391PheGly: 2.391 ± 0.487
0.399PheHis: 0.399 ± 0.427
1.594PheIle: 1.594 ± 0.526
3.189PheLys: 3.189 ± 1.311
4.384PheLeu: 4.384 ± 1.514
0.0PheMet: 0.0 ± 0.0
1.993PheAsn: 1.993 ± 1.047
1.993PhePro: 1.993 ± 0.565
0.797PheGln: 0.797 ± 0.391
0.797PheArg: 0.797 ± 0.443
2.79PheSer: 2.79 ± 0.802
1.594PheThr: 1.594 ± 0.741
3.587PheVal: 3.587 ± 1.414
1.594PheTrp: 1.594 ± 0.881
2.79PheTyr: 2.79 ± 1.086
0.0PheXaa: 0.0 ± 0.0
Gly
4.384GlyAla: 4.384 ± 1.101
1.594GlyCys: 1.594 ± 0.452
5.978GlyAsp: 5.978 ± 1.11
3.189GlyGlu: 3.189 ± 0.943
0.797GlyPhe: 0.797 ± 0.526
6.377GlyGly: 6.377 ± 2.068
2.391GlyHis: 2.391 ± 1.212
3.189GlyIle: 3.189 ± 1.161
3.587GlyLys: 3.587 ± 0.725
3.986GlyLeu: 3.986 ± 0.679
0.797GlyMet: 0.797 ± 0.391
3.587GlyAsn: 3.587 ± 1.217
2.391GlyPro: 2.391 ± 0.768
4.783GlyGln: 4.783 ± 1.225
2.79GlyArg: 2.79 ± 1.479
7.174GlySer: 7.174 ± 1.167
3.986GlyThr: 3.986 ± 1.146
6.776GlyVal: 6.776 ± 0.766
0.797GlyTrp: 0.797 ± 0.458
1.594GlyTyr: 1.594 ± 0.322
0.0GlyXaa: 0.0 ± 0.0
His
2.391HisAla: 2.391 ± 0.435
0.399HisCys: 0.399 ± 0.403
0.797HisAsp: 0.797 ± 0.371
1.196HisGlu: 1.196 ± 0.959
1.594HisPhe: 1.594 ± 0.651
1.196HisGly: 1.196 ± 0.459
1.993HisHis: 1.993 ± 1.334
1.594HisIle: 1.594 ± 0.781
1.196HisLys: 1.196 ± 0.791
2.391HisLeu: 2.391 ± 1.149
0.399HisMet: 0.399 ± 0.346
1.993HisAsn: 1.993 ± 0.742
1.993HisPro: 1.993 ± 0.995
1.196HisGln: 1.196 ± 0.563
1.993HisArg: 1.993 ± 1.132
2.391HisSer: 2.391 ± 0.619
1.196HisThr: 1.196 ± 0.747
2.391HisVal: 2.391 ± 0.806
0.797HisTrp: 0.797 ± 0.443
1.196HisTyr: 1.196 ± 0.791
0.0HisXaa: 0.0 ± 0.0
Ile
1.993IleAla: 1.993 ± 0.75
1.196IleCys: 1.196 ± 0.776
1.993IleAsp: 1.993 ± 1.297
3.189IleGlu: 3.189 ± 1.306
0.797IlePhe: 0.797 ± 0.391
1.993IleGly: 1.993 ± 0.754
1.594IleHis: 1.594 ± 0.426
1.594IleIle: 1.594 ± 0.621
0.797IleLys: 0.797 ± 0.391
1.993IleLeu: 1.993 ± 0.868
0.0IleMet: 0.0 ± 0.0
0.797IleAsn: 0.797 ± 0.807
2.391IlePro: 2.391 ± 1.332
1.993IleGln: 1.993 ± 0.805
1.594IleArg: 1.594 ± 1.043
3.189IleSer: 3.189 ± 1.107
1.993IleThr: 1.993 ± 0.625
4.783IleVal: 4.783 ± 1.432
0.0IleTrp: 0.0 ± 0.0
1.993IleTyr: 1.993 ± 0.674
0.0IleXaa: 0.0 ± 0.0
Lys
3.986LysAla: 3.986 ± 1.503
2.391LysCys: 2.391 ± 1.41
1.594LysAsp: 1.594 ± 1.169
2.79LysGlu: 2.79 ± 1.184
1.993LysPhe: 1.993 ± 1.023
3.189LysGly: 3.189 ± 0.826
1.594LysHis: 1.594 ± 0.781
0.797LysIle: 0.797 ± 0.559
2.391LysLys: 2.391 ± 0.939
3.189LysLeu: 3.189 ± 0.937
0.399LysMet: 0.399 ± 0.35
1.594LysAsn: 1.594 ± 1.385
3.587LysPro: 3.587 ± 1.756
1.993LysGln: 1.993 ± 0.909
5.181LysArg: 5.181 ± 1.417
2.79LysSer: 2.79 ± 1.544
1.993LysThr: 1.993 ± 0.967
3.986LysVal: 3.986 ± 1.788
0.0LysTrp: 0.0 ± 0.0
2.391LysTyr: 2.391 ± 0.485
0.0LysXaa: 0.0 ± 0.0
Leu
5.181LeuAla: 5.181 ± 1.464
3.986LeuCys: 3.986 ± 1.898
4.384LeuAsp: 4.384 ± 0.803
4.384LeuGlu: 4.384 ± 1.151
3.189LeuPhe: 3.189 ± 1.027
4.783LeuGly: 4.783 ± 1.698
2.79LeuHis: 2.79 ± 0.75
2.391LeuIle: 2.391 ± 1.227
5.978LeuLys: 5.978 ± 1.43
7.573LeuLeu: 7.573 ± 2.614
1.594LeuMet: 1.594 ± 1.043
3.986LeuAsn: 3.986 ± 0.895
3.189LeuPro: 3.189 ± 0.867
9.964LeuGln: 9.964 ± 1.569
5.978LeuArg: 5.978 ± 1.11
4.783LeuSer: 4.783 ± 1.317
3.189LeuThr: 3.189 ± 0.529
4.384LeuVal: 4.384 ± 0.948
0.797LeuTrp: 0.797 ± 0.559
3.587LeuTyr: 3.587 ± 1.536
0.0LeuXaa: 0.0 ± 0.0
Met
0.797MetAla: 0.797 ± 0.7
1.196MetCys: 1.196 ± 0.629
1.993MetAsp: 1.993 ± 0.905
0.797MetGlu: 0.797 ± 0.807
0.797MetPhe: 0.797 ± 0.391
1.196MetGly: 1.196 ± 0.507
0.797MetHis: 0.797 ± 0.526
0.399MetIle: 0.399 ± 0.355
1.196MetLys: 1.196 ± 0.485
1.196MetLeu: 1.196 ± 0.651
0.399MetMet: 0.399 ± 0.403
0.0MetAsn: 0.0 ± 0.0
0.0MetPro: 0.0 ± 0.0
0.0MetGln: 0.0 ± 0.0
0.399MetArg: 0.399 ± 0.35
1.594MetSer: 1.594 ± 0.966
1.196MetThr: 1.196 ± 0.392
2.391MetVal: 2.391 ± 0.845
0.797MetTrp: 0.797 ± 0.443
0.399MetTyr: 0.399 ± 0.346
0.0MetXaa: 0.0 ± 0.0
Asn
2.391AsnAla: 2.391 ± 1.211
1.196AsnCys: 1.196 ± 0.538
1.196AsnAsp: 1.196 ± 0.753
1.993AsnGlu: 1.993 ± 0.706
1.196AsnPhe: 1.196 ± 0.719
2.79AsnGly: 2.79 ± 1.045
0.797AsnHis: 0.797 ± 0.807
0.797AsnIle: 0.797 ± 0.535
1.993AsnLys: 1.993 ± 1.751
1.196AsnLeu: 1.196 ± 1.039
0.399AsnMet: 0.399 ± 0.35
2.391AsnAsn: 2.391 ± 1.061
3.587AsnPro: 3.587 ± 0.699
1.196AsnGln: 1.196 ± 0.49
1.196AsnArg: 1.196 ± 0.657
2.79AsnSer: 2.79 ± 0.475
5.181AsnThr: 5.181 ± 0.645
1.993AsnVal: 1.993 ± 0.888
0.797AsnTrp: 0.797 ± 0.458
1.594AsnTyr: 1.594 ± 0.677
0.0AsnXaa: 0.0 ± 0.0
Pro
6.377ProAla: 6.377 ± 2.879
0.797ProCys: 0.797 ± 0.391
4.384ProAsp: 4.384 ± 1.383
2.391ProGlu: 2.391 ± 0.958
1.993ProPhe: 1.993 ± 1.142
2.391ProGly: 2.391 ± 0.983
0.0ProHis: 0.0 ± 0.0
3.189ProIle: 3.189 ± 0.735
3.587ProLys: 3.587 ± 0.978
6.377ProLeu: 6.377 ± 1.691
0.399ProMet: 0.399 ± 0.361
1.594ProAsn: 1.594 ± 0.692
8.768ProPro: 8.768 ± 2.143
1.594ProGln: 1.594 ± 0.933
2.391ProArg: 2.391 ± 0.721
5.181ProSer: 5.181 ± 2.104
3.986ProThr: 3.986 ± 1.519
6.776ProVal: 6.776 ± 2.024
0.797ProTrp: 0.797 ± 0.594
1.993ProTyr: 1.993 ± 1.415
0.0ProXaa: 0.0 ± 0.0
Gln
2.79GlnAla: 2.79 ± 1.245
1.594GlnCys: 1.594 ± 0.836
2.391GlnAsp: 2.391 ± 0.784
1.993GlnGlu: 1.993 ± 0.894
2.391GlnPhe: 2.391 ± 0.68
4.384GlnGly: 4.384 ± 1.111
1.594GlnHis: 1.594 ± 0.778
0.797GlnIle: 0.797 ± 0.526
1.594GlnLys: 1.594 ± 0.78
4.384GlnLeu: 4.384 ± 0.831
1.196GlnMet: 1.196 ± 0.651
1.594GlnAsn: 1.594 ± 0.729
4.384GlnPro: 4.384 ± 1.161
2.79GlnGln: 2.79 ± 0.918
2.79GlnArg: 2.79 ± 1.135
1.196GlnSer: 1.196 ± 1.05
1.993GlnThr: 1.993 ± 0.594
2.79GlnVal: 2.79 ± 0.511
1.594GlnTrp: 1.594 ± 0.804
0.399GlnTyr: 0.399 ± 0.35
0.0GlnXaa: 0.0 ± 0.0
Arg
5.181ArgAla: 5.181 ± 1.345
1.993ArgCys: 1.993 ± 1.026
0.399ArgAsp: 0.399 ± 0.346
1.594ArgGlu: 1.594 ± 0.744
2.391ArgPhe: 2.391 ± 0.727
0.399ArgGly: 0.399 ± 0.35
1.993ArgHis: 1.993 ± 0.801
1.993ArgIle: 1.993 ± 1.002
5.181ArgLys: 5.181 ± 1.178
7.174ArgLeu: 7.174 ± 1.126
1.196ArgMet: 1.196 ± 0.398
0.399ArgAsn: 0.399 ± 0.346
4.783ArgPro: 4.783 ± 1.752
2.391ArgGln: 2.391 ± 0.825
2.79ArgArg: 2.79 ± 0.834
2.79ArgSer: 2.79 ± 0.712
3.986ArgThr: 3.986 ± 1.418
2.391ArgVal: 2.391 ± 0.817
1.196ArgTrp: 1.196 ± 0.544
0.797ArgTyr: 0.797 ± 0.489
0.0ArgXaa: 0.0 ± 0.0
Ser
4.384SerAla: 4.384 ± 1.728
0.797SerCys: 0.797 ± 0.71
5.58SerAsp: 5.58 ± 1.46
3.986SerGlu: 3.986 ± 1.248
3.189SerPhe: 3.189 ± 0.821
7.174SerGly: 7.174 ± 2.151
2.391SerHis: 2.391 ± 0.445
3.587SerIle: 3.587 ± 0.831
2.391SerLys: 2.391 ± 0.635
3.986SerLeu: 3.986 ± 0.921
1.993SerMet: 1.993 ± 1.373
3.587SerAsn: 3.587 ± 1.711
3.587SerPro: 3.587 ± 0.935
1.196SerGln: 1.196 ± 0.459
6.377SerArg: 6.377 ± 1.501
6.377SerSer: 6.377 ± 1.993
5.58SerThr: 5.58 ± 1.442
6.377SerVal: 6.377 ± 0.965
0.0SerTrp: 0.0 ± 0.0
2.79SerTyr: 2.79 ± 1.2
0.0SerXaa: 0.0 ± 0.0
Thr
1.594ThrAla: 1.594 ± 0.979
3.189ThrCys: 3.189 ± 1.052
1.594ThrAsp: 1.594 ± 0.665
3.587ThrGlu: 3.587 ± 0.756
2.79ThrPhe: 2.79 ± 1.029
5.181ThrGly: 5.181 ± 1.295
1.993ThrHis: 1.993 ± 0.754
1.196ThrIle: 1.196 ± 0.734
0.399ThrLys: 0.399 ± 0.35
6.776ThrLeu: 6.776 ± 1.374
1.993ThrMet: 1.993 ± 0.884
1.594ThrAsn: 1.594 ± 0.519
4.783ThrPro: 4.783 ± 0.861
3.587ThrGln: 3.587 ± 0.719
2.391ThrArg: 2.391 ± 0.799
5.58ThrSer: 5.58 ± 1.913
4.384ThrThr: 4.384 ± 1.838
7.573ThrVal: 7.573 ± 3.263
0.797ThrTrp: 0.797 ± 0.458
0.797ThrTyr: 0.797 ± 0.449
0.0ThrXaa: 0.0 ± 0.0
Val
5.978ValAla: 5.978 ± 1.458
2.391ValCys: 2.391 ± 1.51
5.58ValAsp: 5.58 ± 1.218
4.384ValGlu: 4.384 ± 0.673
2.391ValPhe: 2.391 ± 1.262
4.783ValGly: 4.783 ± 0.965
3.986ValHis: 3.986 ± 1.456
2.79ValIle: 2.79 ± 0.841
2.391ValLys: 2.391 ± 0.869
5.978ValLeu: 5.978 ± 2.033
2.391ValMet: 2.391 ± 1.01
1.594ValAsn: 1.594 ± 0.881
5.181ValPro: 5.181 ± 1.707
3.587ValGln: 3.587 ± 2.347
3.189ValArg: 3.189 ± 1.064
8.768ValSer: 8.768 ± 1.41
5.978ValThr: 5.978 ± 2.162
4.384ValVal: 4.384 ± 1.064
1.196ValTrp: 1.196 ± 0.771
3.587ValTyr: 3.587 ± 0.791
0.0ValXaa: 0.0 ± 0.0
Trp
1.196TrpAla: 1.196 ± 0.392
0.0TrpCys: 0.0 ± 0.0
0.399TrpAsp: 0.399 ± 0.427
0.797TrpGlu: 0.797 ± 0.443
0.797TrpPhe: 0.797 ± 0.489
2.391TrpGly: 2.391 ± 1.069
0.399TrpHis: 0.399 ± 0.403
0.797TrpIle: 0.797 ± 0.693
0.797TrpLys: 0.797 ± 0.458
1.196TrpLeu: 1.196 ± 0.537
0.399TrpMet: 0.399 ± 0.346
0.797TrpAsn: 0.797 ± 0.449
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
1.594TrpArg: 1.594 ± 0.452
1.993TrpSer: 1.993 ± 0.959
1.196TrpThr: 1.196 ± 0.769
0.797TrpVal: 0.797 ± 0.458
0.0TrpTrp: 0.0 ± 0.0
0.399TrpTyr: 0.399 ± 0.346
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.391TyrAla: 2.391 ± 0.845
0.797TyrCys: 0.797 ± 0.854
1.993TyrAsp: 1.993 ± 0.622
3.587TyrGlu: 3.587 ± 1.152
1.594TyrPhe: 1.594 ± 0.81
3.986TyrGly: 3.986 ± 0.855
0.797TyrHis: 0.797 ± 0.449
1.594TyrIle: 1.594 ± 0.586
1.594TyrLys: 1.594 ± 0.452
3.587TyrLeu: 3.587 ± 1.184
0.0TyrMet: 0.0 ± 0.0
1.594TyrAsn: 1.594 ± 0.322
1.196TyrPro: 1.196 ± 0.871
0.797TyrGln: 0.797 ± 0.371
1.993TyrArg: 1.993 ± 0.748
1.594TyrSer: 1.594 ± 0.982
1.196TyrThr: 1.196 ± 0.771
3.189TyrVal: 3.189 ± 1.026
0.797TyrTrp: 0.797 ± 0.391
1.196TyrTyr: 1.196 ± 0.689
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 8 proteins (2510 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski