Amino acid dipepetide frequency for Candidatus Uzinura diaspidicola str. ASNER

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.575AlaAla: 2.575 ± 0.211
0.489AlaCys: 0.489 ± 0.078
1.862AlaAsp: 1.862 ± 0.151
2.68AlaGlu: 2.68 ± 0.199
2.575AlaPhe: 2.575 ± 0.165
3.116AlaGly: 3.116 ± 0.23
1.056AlaHis: 1.056 ± 0.111
5.823AlaIle: 5.823 ± 0.323
4.331AlaLys: 4.331 ± 0.25
4.938AlaLeu: 4.938 ± 0.247
1.268AlaMet: 1.268 ± 0.133
2.311AlaAsn: 2.311 ± 0.161
1.307AlaPro: 1.307 ± 0.124
1.545AlaGln: 1.545 ± 0.138
2.02AlaArg: 2.02 ± 0.152
3.327AlaSer: 3.327 ± 0.233
2.007AlaThr: 2.007 ± 0.16
2.337AlaVal: 2.337 ± 0.17
0.343AlaTrp: 0.343 ± 0.067
1.69AlaTyr: 1.69 ± 0.154
0.0AlaXaa: 0.0 ± 0.0
Cys
0.423CysAla: 0.423 ± 0.076
0.066CysCys: 0.066 ± 0.033
0.528CysAsp: 0.528 ± 0.081
0.647CysGlu: 0.647 ± 0.106
0.396CysPhe: 0.396 ± 0.065
0.713CysGly: 0.713 ± 0.099
0.277CysHis: 0.277 ± 0.057
1.413CysIle: 1.413 ± 0.141
0.964CysLys: 0.964 ± 0.111
1.004CysLeu: 1.004 ± 0.105
0.264CysMet: 0.264 ± 0.056
0.687CysAsn: 0.687 ± 0.11
0.462CysPro: 0.462 ± 0.082
0.29CysGln: 0.29 ± 0.072
0.515CysArg: 0.515 ± 0.071
0.792CysSer: 0.792 ± 0.096
0.594CysThr: 0.594 ± 0.082
0.541CysVal: 0.541 ± 0.084
0.053CysTrp: 0.053 ± 0.027
0.568CysTyr: 0.568 ± 0.09
0.0CysXaa: 0.0 ± 0.0
Asp
2.337AspAla: 2.337 ± 0.155
0.343AspCys: 0.343 ± 0.07
2.073AspAsp: 2.073 ± 0.183
2.654AspGlu: 2.654 ± 0.205
2.945AspPhe: 2.945 ± 0.195
2.245AspGly: 2.245 ± 0.164
1.03AspHis: 1.03 ± 0.1
5.757AspIle: 5.757 ± 0.285
4.027AspLys: 4.027 ± 0.272
4.529AspLeu: 4.529 ± 0.28
0.779AspMet: 0.779 ± 0.087
2.39AspAsn: 2.39 ± 0.181
1.386AspPro: 1.386 ± 0.134
0.964AspGln: 0.964 ± 0.117
1.994AspArg: 1.994 ± 0.186
2.68AspSer: 2.68 ± 0.195
2.126AspThr: 2.126 ± 0.17
2.654AspVal: 2.654 ± 0.206
0.383AspTrp: 0.383 ± 0.07
2.007AspTyr: 2.007 ± 0.163
0.0AspXaa: 0.0 ± 0.0
Glu
3.724GluAla: 3.724 ± 0.227
0.7GluCys: 0.7 ± 0.108
3.103GluAsp: 3.103 ± 0.208
5.44GluGlu: 5.44 ± 0.277
2.416GluPhe: 2.416 ± 0.185
3.75GluGly: 3.75 ± 0.288
1.083GluHis: 1.083 ± 0.108
7.975GluIle: 7.975 ± 0.398
7.315GluLys: 7.315 ± 0.314
5.519GluLeu: 5.519 ± 0.255
1.281GluMet: 1.281 ± 0.143
4.186GluAsn: 4.186 ± 0.256
1.307GluPro: 1.307 ± 0.149
1.69GluGln: 1.69 ± 0.14
3.037GluArg: 3.037 ± 0.187
3.856GluSer: 3.856 ± 0.273
2.826GluThr: 2.826 ± 0.196
3.697GluVal: 3.697 ± 0.233
0.449GluTrp: 0.449 ± 0.07
2.179GluTyr: 2.179 ± 0.162
0.0GluXaa: 0.0 ± 0.0
Phe
1.584PheAla: 1.584 ± 0.142
0.885PheCys: 0.885 ± 0.11
2.113PheAsp: 2.113 ± 0.147
2.72PheGlu: 2.72 ± 0.156
2.667PhePhe: 2.667 ± 0.202
2.733PheGly: 2.733 ± 0.18
1.096PheHis: 1.096 ± 0.115
4.516PheIle: 4.516 ± 0.211
4.001PheLys: 4.001 ± 0.232
5.242PheLeu: 5.242 ± 0.287
1.083PheMet: 1.083 ± 0.108
2.601PheAsn: 2.601 ± 0.212
2.113PhePro: 2.113 ± 0.158
1.69PheGln: 1.69 ± 0.162
1.954PheArg: 1.954 ± 0.173
4.793PheSer: 4.793 ± 0.236
2.245PheThr: 2.245 ± 0.196
1.835PheVal: 1.835 ± 0.152
0.396PheTrp: 0.396 ± 0.082
2.905PheTyr: 2.905 ± 0.244
0.0PheXaa: 0.0 ± 0.0
Gly
3.38GlyAla: 3.38 ± 0.225
0.673GlyCys: 0.673 ± 0.103
2.931GlyAsp: 2.931 ± 0.213
3.341GlyGlu: 3.341 ± 0.181
3.222GlyPhe: 3.222 ± 0.206
4.001GlyGly: 4.001 ± 0.294
1.202GlyHis: 1.202 ± 0.134
7.051GlyIle: 7.051 ± 0.329
5.81GlyLys: 5.81 ± 0.303
5.15GlyLeu: 5.15 ± 0.238
1.611GlyMet: 1.611 ± 0.188
2.905GlyAsn: 2.905 ± 0.207
1.386GlyPro: 1.386 ± 0.138
1.624GlyGln: 1.624 ± 0.174
2.852GlyArg: 2.852 ± 0.195
4.04GlySer: 4.04 ± 0.293
2.826GlyThr: 2.826 ± 0.169
3.618GlyVal: 3.618 ± 0.254
0.528GlyTrp: 0.528 ± 0.1
2.773GlyTyr: 2.773 ± 0.189
0.0GlyXaa: 0.0 ± 0.0
His
1.043HisAla: 1.043 ± 0.121
0.304HisCys: 0.304 ± 0.061
0.634HisAsp: 0.634 ± 0.092
0.832HisGlu: 0.832 ± 0.105
0.99HisPhe: 0.99 ± 0.117
1.36HisGly: 1.36 ± 0.149
0.7HisHis: 0.7 ± 0.093
2.892HisIle: 2.892 ± 0.191
1.769HisLys: 1.769 ± 0.161
2.548HisLeu: 2.548 ± 0.202
0.172HisMet: 0.172 ± 0.041
1.096HisAsn: 1.096 ± 0.136
1.254HisPro: 1.254 ± 0.137
0.66HisGln: 0.66 ± 0.092
1.03HisArg: 1.03 ± 0.119
1.492HisSer: 1.492 ± 0.125
0.937HisThr: 0.937 ± 0.099
0.937HisVal: 0.937 ± 0.121
0.317HisTrp: 0.317 ± 0.073
1.017HisTyr: 1.017 ± 0.112
0.0HisXaa: 0.0 ± 0.0
Ile
5.453IleAla: 5.453 ± 0.294
1.505IleCys: 1.505 ± 0.163
5.902IleAsp: 5.902 ± 0.266
8.187IleGlu: 8.187 ± 0.318
5.519IlePhe: 5.519 ± 0.274
7.051IleGly: 7.051 ± 0.298
2.694IleHis: 2.694 ± 0.182
10.233IleIle: 10.233 ± 0.334
10.167IleLys: 10.167 ± 0.448
10.114IleLeu: 10.114 ± 0.347
1.743IleMet: 1.743 ± 0.158
5.453IleAsn: 5.453 ± 0.291
3.79IlePro: 3.79 ± 0.275
3.658IleGln: 3.658 ± 0.197
4.489IleArg: 4.489 ± 0.254
9.084IleSer: 9.084 ± 0.371
5.123IleThr: 5.123 ± 0.256
5.123IleVal: 5.123 ± 0.273
0.555IleTrp: 0.555 ± 0.087
4.265IleTyr: 4.265 ± 0.205
0.0IleXaa: 0.0 ± 0.0
Lys
4.476LysAla: 4.476 ± 0.232
0.832LysCys: 0.832 ± 0.097
3.75LysAsp: 3.75 ± 0.235
8.292LysGlu: 8.292 ± 0.422
3.42LysPhe: 3.42 ± 0.205
5.546LysGly: 5.546 ± 0.245
1.32LysHis: 1.32 ± 0.136
11.554LysIle: 11.554 ± 0.384
12.425LysLys: 12.425 ± 0.473
6.985LysLeu: 6.985 ± 0.303
1.967LysMet: 1.967 ± 0.151
7.051LysAsn: 7.051 ± 0.4
2.073LysPro: 2.073 ± 0.173
2.588LysGln: 2.588 ± 0.212
4.529LysArg: 4.529 ± 0.279
5.546LysSer: 5.546 ± 0.248
4.608LysThr: 4.608 ± 0.277
5.031LysVal: 5.031 ± 0.278
0.647LysTrp: 0.647 ± 0.093
4.437LysTyr: 4.437 ± 0.225
0.0LysXaa: 0.0 ± 0.0
Leu
4.291LeuAla: 4.291 ± 0.245
0.964LeuCys: 0.964 ± 0.121
4.555LeuAsp: 4.555 ± 0.26
6.483LeuGlu: 6.483 ± 0.271
4.225LeuPhe: 4.225 ± 0.26
5.929LeuGly: 5.929 ± 0.261
2.628LeuHis: 2.628 ± 0.207
7.658LeuIle: 7.658 ± 0.346
8.635LeuLys: 8.635 ± 0.364
8.86LeuLeu: 8.86 ± 0.377
1.664LeuMet: 1.664 ± 0.145
5.202LeuAsn: 5.202 ± 0.293
3.354LeuPro: 3.354 ± 0.21
3.222LeuGln: 3.222 ± 0.242
4.529LeuArg: 4.529 ± 0.277
7.606LeuSer: 7.606 ± 0.319
3.433LeuThr: 3.433 ± 0.216
4.503LeuVal: 4.503 ± 0.227
0.528LeuTrp: 0.528 ± 0.072
4.014LeuTyr: 4.014 ± 0.252
0.0LeuXaa: 0.0 ± 0.0
Met
1.373MetAla: 1.373 ± 0.134
0.145MetCys: 0.145 ± 0.043
0.937MetAsp: 0.937 ± 0.125
1.215MetGlu: 1.215 ± 0.125
0.819MetPhe: 0.819 ± 0.106
1.334MetGly: 1.334 ± 0.132
0.489MetHis: 0.489 ± 0.077
2.02MetIle: 2.02 ± 0.152
2.231MetLys: 2.231 ± 0.178
1.835MetLeu: 1.835 ± 0.154
0.528MetMet: 0.528 ± 0.088
1.413MetAsn: 1.413 ± 0.146
0.911MetPro: 0.911 ± 0.099
0.673MetGln: 0.673 ± 0.083
0.977MetArg: 0.977 ± 0.11
1.175MetSer: 1.175 ± 0.14
0.792MetThr: 0.792 ± 0.103
0.898MetVal: 0.898 ± 0.1
0.04MetTrp: 0.04 ± 0.024
0.739MetTyr: 0.739 ± 0.103
0.0MetXaa: 0.0 ± 0.0
Asn
2.509AsnAla: 2.509 ± 0.176
0.792AsnCys: 0.792 ± 0.096
2.271AsnAsp: 2.271 ± 0.173
3.195AsnGlu: 3.195 ± 0.184
2.958AsnPhe: 2.958 ± 0.179
2.878AsnGly: 2.878 ± 0.204
1.149AsnHis: 1.149 ± 0.117
7.236AsnIle: 7.236 ± 0.338
5.533AsnLys: 5.533 ± 0.26
5.282AsnLeu: 5.282 ± 0.311
1.413AsnMet: 1.413 ± 0.127
3.222AsnAsn: 3.222 ± 0.212
2.073AsnPro: 2.073 ± 0.149
1.32AsnGln: 1.32 ± 0.131
2.284AsnArg: 2.284 ± 0.169
3.354AsnSer: 3.354 ± 0.252
2.958AsnThr: 2.958 ± 0.191
2.482AsnVal: 2.482 ± 0.144
0.673AsnTrp: 0.673 ± 0.103
2.403AsnTyr: 2.403 ± 0.148
0.0AsnXaa: 0.0 ± 0.0
Pro
1.03ProAla: 1.03 ± 0.113
0.357ProCys: 0.357 ± 0.079
1.202ProAsp: 1.202 ± 0.133
1.835ProGlu: 1.835 ± 0.159
1.664ProPhe: 1.664 ± 0.142
1.928ProGly: 1.928 ± 0.162
0.713ProHis: 0.713 ± 0.087
4.146ProIle: 4.146 ± 0.221
2.601ProLys: 2.601 ± 0.196
3.235ProLeu: 3.235 ± 0.181
0.568ProMet: 0.568 ± 0.081
1.783ProAsn: 1.783 ± 0.133
0.634ProPro: 0.634 ± 0.102
0.964ProGln: 0.964 ± 0.121
0.924ProArg: 0.924 ± 0.114
2.535ProSer: 2.535 ± 0.191
1.584ProThr: 1.584 ± 0.13
1.532ProVal: 1.532 ± 0.148
0.238ProTrp: 0.238 ± 0.075
1.466ProTyr: 1.466 ± 0.107
0.0ProXaa: 0.0 ± 0.0
Gln
1.598GlnAla: 1.598 ± 0.162
0.251GlnCys: 0.251 ± 0.052
1.228GlnAsp: 1.228 ± 0.111
2.205GlnGlu: 2.205 ± 0.186
1.373GlnPhe: 1.373 ± 0.157
1.703GlnGly: 1.703 ± 0.137
0.647GlnHis: 0.647 ± 0.09
3.182GlnIle: 3.182 ± 0.189
2.852GlnLys: 2.852 ± 0.185
3.09GlnLeu: 3.09 ± 0.201
0.713GlnMet: 0.713 ± 0.089
1.36GlnAsn: 1.36 ± 0.128
0.621GlnPro: 0.621 ± 0.096
0.726GlnGln: 0.726 ± 0.091
1.4GlnArg: 1.4 ± 0.125
1.584GlnSer: 1.584 ± 0.142
1.215GlnThr: 1.215 ± 0.134
1.796GlnVal: 1.796 ± 0.142
0.264GlnTrp: 0.264 ± 0.068
1.386GlnTyr: 1.386 ± 0.138
0.0GlnXaa: 0.0 ± 0.0
Arg
1.756ArgAla: 1.756 ± 0.143
0.29ArgCys: 0.29 ± 0.06
2.007ArgAsp: 2.007 ± 0.19
2.535ArgGlu: 2.535 ± 0.203
2.231ArgPhe: 2.231 ± 0.16
2.271ArgGly: 2.271 ± 0.207
0.819ArgHis: 0.819 ± 0.099
4.727ArgIle: 4.727 ± 0.279
4.938ArgLys: 4.938 ± 0.287
3.644ArgLeu: 3.644 ± 0.24
1.268ArgMet: 1.268 ± 0.141
2.997ArgAsn: 2.997 ± 0.197
1.149ArgPro: 1.149 ± 0.139
1.426ArgGln: 1.426 ± 0.148
2.205ArgArg: 2.205 ± 0.168
3.116ArgSer: 3.116 ± 0.193
1.994ArgThr: 1.994 ± 0.149
2.456ArgVal: 2.456 ± 0.166
0.277ArgTrp: 0.277 ± 0.063
2.324ArgTyr: 2.324 ± 0.18
0.0ArgXaa: 0.0 ± 0.0
Ser
2.799SerAla: 2.799 ± 0.179
0.792SerCys: 0.792 ± 0.1
2.68SerAsp: 2.68 ± 0.18
3.671SerGlu: 3.671 ± 0.213
4.225SerPhe: 4.225 ± 0.231
4.952SerGly: 4.952 ± 0.276
1.532SerHis: 1.532 ± 0.166
8.873SerIle: 8.873 ± 0.33
5.968SerLys: 5.968 ± 0.28
6.866SerLeu: 6.866 ± 0.328
1.466SerMet: 1.466 ± 0.168
3.473SerAsn: 3.473 ± 0.224
2.324SerPro: 2.324 ± 0.184
1.849SerGln: 1.849 ± 0.166
3.037SerArg: 3.037 ± 0.237
6.074SerSer: 6.074 ± 0.31
3.209SerThr: 3.209 ± 0.191
3.684SerVal: 3.684 ± 0.222
0.607SerTrp: 0.607 ± 0.115
3.565SerTyr: 3.565 ± 0.201
0.0SerXaa: 0.0 ± 0.0
Thr
2.06ThrAla: 2.06 ± 0.146
0.357ThrCys: 0.357 ± 0.085
2.099ThrAsp: 2.099 ± 0.157
2.852ThrGlu: 2.852 ± 0.199
2.469ThrPhe: 2.469 ± 0.174
3.156ThrGly: 3.156 ± 0.198
1.07ThrHis: 1.07 ± 0.134
4.819ThrIle: 4.819 ± 0.292
4.291ThrLys: 4.291 ± 0.202
4.305ThrLeu: 4.305 ± 0.207
0.885ThrMet: 0.885 ± 0.108
2.245ThrAsn: 2.245 ± 0.16
1.822ThrPro: 1.822 ± 0.138
1.215ThrGln: 1.215 ± 0.107
1.677ThrArg: 1.677 ± 0.154
3.341ThrSer: 3.341 ± 0.203
2.192ThrThr: 2.192 ± 0.167
2.086ThrVal: 2.086 ± 0.165
0.185ThrTrp: 0.185 ± 0.049
1.558ThrTyr: 1.558 ± 0.157
0.0ThrXaa: 0.0 ± 0.0
Val
3.063ValAla: 3.063 ± 0.257
0.515ValCys: 0.515 ± 0.086
2.931ValAsp: 2.931 ± 0.202
3.592ValGlu: 3.592 ± 0.217
2.271ValPhe: 2.271 ± 0.172
3.288ValGly: 3.288 ± 0.229
1.122ValHis: 1.122 ± 0.15
5.453ValIle: 5.453 ± 0.256
4.199ValLys: 4.199 ± 0.222
4.437ValLeu: 4.437 ± 0.217
0.779ValMet: 0.779 ± 0.093
2.72ValAsn: 2.72 ± 0.143
1.518ValPro: 1.518 ± 0.138
1.307ValGln: 1.307 ± 0.125
2.284ValArg: 2.284 ± 0.181
4.067ValSer: 4.067 ± 0.24
1.796ValThr: 1.796 ± 0.147
3.235ValVal: 3.235 ± 0.201
0.37ValTrp: 0.37 ± 0.073
1.862ValTyr: 1.862 ± 0.155
0.0ValXaa: 0.0 ± 0.0
Trp
0.317TrpAla: 0.317 ± 0.071
0.119TrpCys: 0.119 ± 0.041
0.277TrpAsp: 0.277 ± 0.065
0.528TrpGlu: 0.528 ± 0.082
0.304TrpPhe: 0.304 ± 0.075
0.396TrpGly: 0.396 ± 0.074
0.211TrpHis: 0.211 ± 0.06
0.805TrpIle: 0.805 ± 0.101
0.766TrpLys: 0.766 ± 0.132
0.607TrpLeu: 0.607 ± 0.09
0.224TrpMet: 0.224 ± 0.052
0.383TrpAsn: 0.383 ± 0.073
0.172TrpPro: 0.172 ± 0.05
0.238TrpGln: 0.238 ± 0.061
0.449TrpArg: 0.449 ± 0.088
0.317TrpSer: 0.317 ± 0.06
0.304TrpThr: 0.304 ± 0.067
0.502TrpVal: 0.502 ± 0.084
0.106TrpTrp: 0.106 ± 0.034
0.343TrpTyr: 0.343 ± 0.074
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.809TyrAla: 1.809 ± 0.161
0.819TyrCys: 0.819 ± 0.081
2.218TyrAsp: 2.218 ± 0.156
2.628TyrGlu: 2.628 ± 0.217
2.482TyrPhe: 2.482 ± 0.22
2.575TyrGly: 2.575 ± 0.193
1.149TyrHis: 1.149 ± 0.154
3.988TyrIle: 3.988 ± 0.233
4.252TyrLys: 4.252 ± 0.294
4.093TyrLeu: 4.093 ± 0.188
0.858TyrMet: 0.858 ± 0.106
2.509TyrAsn: 2.509 ± 0.178
1.281TyrPro: 1.281 ± 0.13
1.545TyrGln: 1.545 ± 0.147
2.245TyrArg: 2.245 ± 0.162
2.865TyrSer: 2.865 ± 0.204
1.915TyrThr: 1.915 ± 0.164
1.862TyrVal: 1.862 ± 0.153
0.409TyrTrp: 0.409 ± 0.088
1.717TyrTyr: 1.717 ± 0.168
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 227 proteins (75735 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski