Amino acid dipepetide frequency for Syncephalastrum racemosum (Filamentous fungus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.585AlaAla: 8.585 ± 0.078	1.229AlaCys: 1.229 ± 0.017	4.123AlaAsp: 4.123 ± 0.029	4.619AlaGlu: 4.619 ± 0.042	3.128AlaPhe: 3.128 ± 0.036	4.499AlaGly: 4.499 ± 0.042	1.964AlaHis: 1.964 ± 0.023	4.172AlaIle: 4.172 ± 0.035	4.086AlaLys: 4.086 ± 0.035	7.681AlaLeu: 7.681 ± 0.048	2.185AlaMet: 2.185 ± 0.025	2.9AlaAsn: 2.9 ± 0.026	4.168AlaPro: 4.168 ± 0.038	3.491AlaGln: 3.491 ± 0.032	4.51AlaArg: 4.51 ± 0.04	6.883AlaSer: 6.883 ± 0.044	5.094AlaThr: 5.094 ± 0.038	5.09AlaVal: 5.09 ± 0.043	0.978AlaTrp: 0.978 ± 0.017	2.347AlaTyr: 2.347 ± 0.025	0.0AlaXaa: 0.0 ± 0.0
Cys	0.988CysAla: 0.988 ± 0.015	0.345CysCys: 0.345 ± 0.012	0.738CysAsp: 0.738 ± 0.013	0.666CysGlu: 0.666 ± 0.015	0.694CysPhe: 0.694 ± 0.014	0.93CysGly: 0.93 ± 0.016	0.472CysHis: 0.472 ± 0.014	0.876CysIle: 0.876 ± 0.014	0.631CysLys: 0.631 ± 0.012	1.48CysLeu: 1.48 ± 0.022	0.38CysMet: 0.38 ± 0.01	0.507CysAsn: 0.507 ± 0.013	0.75CysPro: 0.75 ± 0.016	0.585CysGln: 0.585 ± 0.014	0.879CysArg: 0.879 ± 0.017	1.039CysSer: 1.039 ± 0.017	0.779CysThr: 0.779 ± 0.014	0.963CysVal: 0.963 ± 0.017	0.186CysTrp: 0.186 ± 0.007	0.475CysTyr: 0.475 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	4.775AspAla: 4.775 ± 0.036	0.684AspCys: 0.684 ± 0.014	4.83AspAsp: 4.83 ± 0.054	4.698AspGlu: 4.698 ± 0.048	2.17AspPhe: 2.17 ± 0.025	3.197AspGly: 3.197 ± 0.029	1.488AspHis: 1.488 ± 0.02	3.271AspIle: 3.271 ± 0.028	2.919AspLys: 2.919 ± 0.03	5.238AspLeu: 5.238 ± 0.04	1.665AspMet: 1.665 ± 0.019	2.184AspAsn: 2.184 ± 0.024	3.077AspPro: 3.077 ± 0.027	2.338AspGln: 2.338 ± 0.028	3.03AspArg: 3.03 ± 0.034	3.507AspSer: 3.507 ± 0.029	3.513AspThr: 3.513 ± 0.031	3.587AspVal: 3.587 ± 0.029	0.785AspTrp: 0.785 ± 0.014	1.902AspTyr: 1.902 ± 0.026	0.0AspXaa: 0.0 ± 0.0
Glu	4.919GluAla: 4.919 ± 0.045	0.712GluCys: 0.712 ± 0.014	4.336GluAsp: 4.336 ± 0.046	5.855GluGlu: 5.855 ± 0.072	1.917GluPhe: 1.917 ± 0.023	2.976GluGly: 2.976 ± 0.028	1.67GluHis: 1.67 ± 0.022	2.843GluIle: 2.843 ± 0.028	3.94GluLys: 3.94 ± 0.042	5.305GluLeu: 5.305 ± 0.044	1.451GluMet: 1.451 ± 0.017	2.52GluAsn: 2.52 ± 0.028	2.632GluPro: 2.632 ± 0.029	3.287GluGln: 3.287 ± 0.031	3.921GluArg: 3.921 ± 0.04	3.803GluSer: 3.803 ± 0.035	3.448GluThr: 3.448 ± 0.033	3.065GluVal: 3.065 ± 0.038	0.703GluTrp: 0.703 ± 0.012	1.878GluTyr: 1.878 ± 0.023	0.0GluXaa: 0.0 ± 0.0
Phe	2.939PheAla: 2.939 ± 0.03	0.747PheCys: 0.747 ± 0.025	2.412PheAsp: 2.412 ± 0.02	2.221PheGlu: 2.221 ± 0.026	1.769PhePhe: 1.769 ± 0.027	2.616PheGly: 2.616 ± 0.031	0.979PheHis: 0.979 ± 0.014	1.923PheIle: 1.923 ± 0.027	1.649PheLys: 1.649 ± 0.023	3.657PheLeu: 3.657 ± 0.037	0.995PheMet: 0.995 ± 0.019	1.397PheAsn: 1.397 ± 0.02	1.674PhePro: 1.674 ± 0.017	1.41PheGln: 1.41 ± 0.02	1.922PheArg: 1.922 ± 0.023	2.921PheSer: 2.921 ± 0.03	1.996PheThr: 1.996 ± 0.022	2.592PheVal: 2.592 ± 0.027	0.565PheTrp: 0.565 ± 0.013	1.346PheTyr: 1.346 ± 0.02	0.0PheXaa: 0.0 ± 0.0
Gly	4.203GlyAla: 4.203 ± 0.045	0.837GlyCys: 0.837 ± 0.016	3.048GlyAsp: 3.048 ± 0.03	2.935GlyGlu: 2.935 ± 0.028	2.375GlyPhe: 2.375 ± 0.027	4.128GlyGly: 4.128 ± 0.062	1.554GlyHis: 1.554 ± 0.02	2.984GlyIle: 2.984 ± 0.031	3.036GlyLys: 3.036 ± 0.029	4.918GlyLeu: 4.918 ± 0.037	1.404GlyMet: 1.404 ± 0.021	2.133GlyAsn: 2.133 ± 0.024	2.297GlyPro: 2.297 ± 0.026	2.323GlyGln: 2.323 ± 0.026	3.236GlyArg: 3.236 ± 0.03	4.407GlySer: 4.407 ± 0.038	3.179GlyThr: 3.179 ± 0.031	3.561GlyVal: 3.561 ± 0.034	0.875GlyTrp: 0.875 ± 0.016	1.992GlyTyr: 1.992 ± 0.025	0.0GlyXaa: 0.0 ± 0.0
His	2.152HisAla: 2.152 ± 0.025	0.432HisCys: 0.432 ± 0.01	1.591HisAsp: 1.591 ± 0.024	1.501HisGlu: 1.501 ± 0.02	1.054HisPhe: 1.054 ± 0.017	1.591HisGly: 1.591 ± 0.023	1.463HisHis: 1.463 ± 0.032	1.449HisIle: 1.449 ± 0.02	1.189HisLys: 1.189 ± 0.018	2.616HisLeu: 2.616 ± 0.027	0.688HisMet: 0.688 ± 0.013	1.023HisAsn: 1.023 ± 0.018	1.89HisPro: 1.89 ± 0.023	1.44HisGln: 1.44 ± 0.025	1.751HisArg: 1.751 ± 0.019	1.911HisSer: 1.911 ± 0.022	1.596HisThr: 1.596 ± 0.02	1.767HisVal: 1.767 ± 0.02	0.333HisTrp: 0.333 ± 0.009	0.939HisTyr: 0.939 ± 0.014	0.0HisXaa: 0.0 ± 0.0
Ile	3.958IleAla: 3.958 ± 0.032	0.816IleCys: 0.816 ± 0.015	2.977IleAsp: 2.977 ± 0.029	2.921IleGlu: 2.921 ± 0.03	1.976IlePhe: 1.976 ± 0.029	2.752IleGly: 2.752 ± 0.027	1.462IleHis: 1.462 ± 0.024	2.491IleIle: 2.491 ± 0.032	2.613IleLys: 2.613 ± 0.028	4.7IleLeu: 4.7 ± 0.039	1.272IleMet: 1.272 ± 0.016	1.835IleAsn: 1.835 ± 0.025	2.744IlePro: 2.744 ± 0.025	2.246IleGln: 2.246 ± 0.025	2.893IleArg: 2.893 ± 0.026	3.362IleSer: 3.362 ± 0.029	2.747IleThr: 2.747 ± 0.025	3.275IleVal: 3.275 ± 0.026	0.608IleTrp: 0.608 ± 0.017	1.611IleTyr: 1.611 ± 0.019	0.0IleXaa: 0.0 ± 0.0
Lys	4.172LysAla: 4.172 ± 0.038	0.594LysCys: 0.594 ± 0.013	3.13LysAsp: 3.13 ± 0.033	3.737LysGlu: 3.737 ± 0.042	1.488LysPhe: 1.488 ± 0.018	2.466LysGly: 2.466 ± 0.028	1.446LysHis: 1.446 ± 0.02	2.384LysIle: 2.384 ± 0.028	4.027LysLys: 4.027 ± 0.049	4.397LysLeu: 4.397 ± 0.03	1.217LysMet: 1.217 ± 0.016	2.043LysAsn: 2.043 ± 0.022	2.593LysPro: 2.593 ± 0.027	2.681LysGln: 2.681 ± 0.028	3.871LysArg: 3.871 ± 0.038	3.441LysSer: 3.441 ± 0.03	3.012LysThr: 3.012 ± 0.028	2.924LysVal: 2.924 ± 0.026	0.522LysTrp: 0.522 ± 0.01	1.662LysTyr: 1.662 ± 0.022	0.0LysXaa: 0.0 ± 0.0
Leu	7.555LeuAla: 7.555 ± 0.049	1.525LeuCys: 1.525 ± 0.019	5.469LeuAsp: 5.469 ± 0.037	5.58LeuGlu: 5.58 ± 0.044	3.663LeuPhe: 3.663 ± 0.035	5.075LeuGly: 5.075 ± 0.041	2.469LeuHis: 2.469 ± 0.024	4.028LeuIle: 4.028 ± 0.036	4.57LeuLys: 4.57 ± 0.04	8.989LeuLeu: 8.989 ± 0.065	2.177LeuMet: 2.177 ± 0.023	3.285LeuAsn: 3.285 ± 0.029	5.08LeuPro: 5.08 ± 0.039	4.477LeuGln: 4.477 ± 0.038	5.581LeuArg: 5.581 ± 0.039	7.212LeuSer: 7.212 ± 0.04	5.047LeuThr: 5.047 ± 0.042	5.719LeuVal: 5.719 ± 0.042	1.102LeuTrp: 1.102 ± 0.016	2.813LeuTyr: 2.813 ± 0.026	0.0LeuXaa: 0.0 ± 0.0
Met	2.285MetAla: 2.285 ± 0.026	0.315MetCys: 0.315 ± 0.009	1.621MetAsp: 1.621 ± 0.019	1.497MetGlu: 1.497 ± 0.018	0.828MetPhe: 0.828 ± 0.014	1.348MetGly: 1.348 ± 0.02	0.654MetHis: 0.654 ± 0.011	1.18MetIle: 1.18 ± 0.018	1.091MetLys: 1.091 ± 0.017	2.312MetLeu: 2.312 ± 0.023	0.787MetMet: 0.787 ± 0.016	0.965MetAsn: 0.965 ± 0.016	1.45MetPro: 1.45 ± 0.019	1.157MetGln: 1.157 ± 0.017	1.497MetArg: 1.497 ± 0.018	1.98MetSer: 1.98 ± 0.022	1.63MetThr: 1.63 ± 0.017	1.585MetVal: 1.585 ± 0.023	0.261MetTrp: 0.261 ± 0.008	0.713MetTyr: 0.713 ± 0.012	0.0MetXaa: 0.0 ± 0.0
Asn	3.179AsnAla: 3.179 ± 0.025	0.473AsnCys: 0.473 ± 0.011	2.371AsnAsp: 2.371 ± 0.025	2.312AsnGlu: 2.312 ± 0.024	1.314AsnPhe: 1.314 ± 0.02	2.365AsnGly: 2.365 ± 0.022	1.015AsnHis: 1.015 ± 0.017	2.0AsnIle: 2.0 ± 0.023	2.074AsnLys: 2.074 ± 0.024	3.185AsnLeu: 3.185 ± 0.028	1.054AsnMet: 1.054 ± 0.015	1.971AsnAsn: 1.971 ± 0.031	2.088AsnPro: 2.088 ± 0.022	1.581AsnGln: 1.581 ± 0.018	1.963AsnArg: 1.963 ± 0.022	2.421AsnSer: 2.421 ± 0.023	2.337AsnThr: 2.337 ± 0.025	2.505AsnVal: 2.505 ± 0.026	0.462AsnTrp: 0.462 ± 0.011	1.197AsnTyr: 1.197 ± 0.018	0.0AsnXaa: 0.0 ± 0.0
Pro	4.712ProAla: 4.712 ± 0.04	0.571ProCys: 0.571 ± 0.011	2.905ProAsp: 2.905 ± 0.029	3.348ProGlu: 3.348 ± 0.03	2.005ProPhe: 2.005 ± 0.02	2.668ProGly: 2.668 ± 0.027	1.482ProHis: 1.482 ± 0.02	2.371ProIle: 2.371 ± 0.022	2.439ProLys: 2.439 ± 0.029	4.482ProLeu: 4.482 ± 0.033	1.184ProMet: 1.184 ± 0.016	2.026ProAsn: 2.026 ± 0.021	5.193ProPro: 5.193 ± 0.08	2.574ProGln: 2.574 ± 0.034	2.936ProArg: 2.936 ± 0.027	5.69ProSer: 5.69 ± 0.052	3.585ProThr: 3.585 ± 0.031	3.444ProVal: 3.444 ± 0.031	0.569ProTrp: 0.569 ± 0.01	1.601ProTyr: 1.601 ± 0.021	0.0ProXaa: 0.0 ± 0.0
Gln	3.564GlnAla: 3.564 ± 0.036	0.575GlnCys: 0.575 ± 0.013	2.521GlnAsp: 2.521 ± 0.031	3.045GlnGlu: 3.045 ± 0.032	1.459GlnPhe: 1.459 ± 0.019	2.245GlnGly: 2.245 ± 0.025	1.745GlnHis: 1.745 ± 0.023	1.981GlnIle: 1.981 ± 0.021	2.5GlnLys: 2.5 ± 0.026	4.205GlnLeu: 4.205 ± 0.036	1.111GlnMet: 1.111 ± 0.016	1.649GlnAsn: 1.649 ± 0.02	2.879GlnPro: 2.879 ± 0.037	5.806GlnGln: 5.806 ± 0.107	3.166GlnArg: 3.166 ± 0.034	3.135GlnSer: 3.135 ± 0.026	2.483GlnThr: 2.483 ± 0.028	2.582GlnVal: 2.582 ± 0.026	0.562GlnTrp: 0.562 ± 0.011	1.42GlnTyr: 1.42 ± 0.019	0.0GlnXaa: 0.0 ± 0.0
Arg	4.31ArgAla: 4.31 ± 0.04	0.831ArgCys: 0.831 ± 0.016	3.157ArgAsp: 3.157 ± 0.032	3.416ArgGlu: 3.416 ± 0.034	2.216ArgPhe: 2.216 ± 0.023	2.913ArgGly: 2.913 ± 0.035	1.936ArgHis: 1.936 ± 0.025	3.076ArgIle: 3.076 ± 0.028	3.547ArgLys: 3.547 ± 0.038	5.697ArgLeu: 5.697 ± 0.043	1.462ArgMet: 1.462 ± 0.016	2.218ArgAsn: 2.218 ± 0.025	3.166ArgPro: 3.166 ± 0.029	3.056ArgGln: 3.056 ± 0.034	5.124ArgArg: 5.124 ± 0.058	4.487ArgSer: 4.487 ± 0.044	3.193ArgThr: 3.193 ± 0.029	3.42ArgVal: 3.42 ± 0.029	0.817ArgTrp: 0.817 ± 0.015	1.864ArgTyr: 1.864 ± 0.024	0.0ArgXaa: 0.0 ± 0.0
Ser	6.232SerAla: 6.232 ± 0.038	0.973SerCys: 0.973 ± 0.017	4.022SerAsp: 4.022 ± 0.034	3.766SerGlu: 3.766 ± 0.034	2.957SerPhe: 2.957 ± 0.028	4.338SerGly: 4.338 ± 0.035	1.994SerHis: 1.994 ± 0.024	3.768SerIle: 3.768 ± 0.038	3.602SerLys: 3.602 ± 0.032	6.875SerLeu: 6.875 ± 0.049	1.985SerMet: 1.985 ± 0.02	3.007SerAsn: 3.007 ± 0.03	4.956SerPro: 4.956 ± 0.055	3.244SerGln: 3.244 ± 0.032	4.286SerArg: 4.286 ± 0.038	9.405SerSer: 9.405 ± 0.092	5.37SerThr: 5.37 ± 0.047	4.464SerVal: 4.464 ± 0.035	0.881SerTrp: 0.881 ± 0.015	2.101SerTyr: 2.101 ± 0.026	0.0SerXaa: 0.0 ± 0.0
Thr	5.063ThrAla: 5.063 ± 0.037	0.866ThrCys: 0.866 ± 0.013	3.04ThrAsp: 3.04 ± 0.029	3.105ThrGlu: 3.105 ± 0.038	2.287ThrPhe: 2.287 ± 0.025	3.415ThrGly: 3.415 ± 0.03	1.59ThrHis: 1.59 ± 0.019	3.058ThrIle: 3.058 ± 0.036	2.701ThrLys: 2.701 ± 0.026	5.56ThrLeu: 5.56 ± 0.041	1.433ThrMet: 1.433 ± 0.022	2.111ThrAsn: 2.111 ± 0.026	3.827ThrPro: 3.827 ± 0.035	2.299ThrGln: 2.299 ± 0.025	3.201ThrArg: 3.201 ± 0.034	5.128ThrSer: 5.128 ± 0.044	4.564ThrThr: 4.564 ± 0.06	3.846ThrVal: 3.846 ± 0.037	0.726ThrTrp: 0.726 ± 0.014	1.715ThrTyr: 1.715 ± 0.022	0.0ThrXaa: 0.0 ± 0.0
Val	4.957ValAla: 4.957 ± 0.041	1.051ValCys: 1.051 ± 0.02	3.811ValAsp: 3.811 ± 0.031	3.588ValGlu: 3.588 ± 0.028	2.542ValPhe: 2.542 ± 0.029	3.284ValGly: 3.284 ± 0.034	1.667ValHis: 1.667 ± 0.018	3.09ValIle: 3.09 ± 0.03	3.033ValLys: 3.033 ± 0.035	5.906ValLeu: 5.906 ± 0.038	1.538ValMet: 1.538 ± 0.018	2.27ValAsn: 2.27 ± 0.024	3.301ValPro: 3.301 ± 0.028	2.679ValGln: 2.679 ± 0.028	3.463ValArg: 3.463 ± 0.034	4.551ValSer: 4.551 ± 0.039	3.412ValThr: 3.412 ± 0.037	4.212ValVal: 4.212 ± 0.037	0.763ValTrp: 0.763 ± 0.015	2.033ValTyr: 2.033 ± 0.023	0.0ValXaa: 0.0 ± 0.0
Trp	0.832TrpAla: 0.832 ± 0.016	0.225TrpCys: 0.225 ± 0.008	0.757TrpAsp: 0.757 ± 0.017	0.621TrpGlu: 0.621 ± 0.012	0.522TrpPhe: 0.522 ± 0.013	0.62TrpGly: 0.62 ± 0.014	0.355TrpHis: 0.355 ± 0.01	0.698TrpIle: 0.698 ± 0.014	0.672TrpLys: 0.672 ± 0.012	1.214TrpLeu: 1.214 ± 0.018	0.36TrpMet: 0.36 ± 0.01	0.513TrpAsn: 0.513 ± 0.013	0.464TrpPro: 0.464 ± 0.01	0.601TrpGln: 0.601 ± 0.012	0.859TrpArg: 0.859 ± 0.015	0.952TrpSer: 0.952 ± 0.017	0.768TrpThr: 0.768 ± 0.017	0.693TrpVal: 0.693 ± 0.014	0.219TrpTrp: 0.219 ± 0.009	0.392TrpTyr: 0.392 ± 0.01	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.353TyrAla: 2.353 ± 0.025	0.564TyrCys: 0.564 ± 0.013	1.995TyrAsp: 1.995 ± 0.024	1.749TyrGlu: 1.749 ± 0.021	1.363TyrPhe: 1.363 ± 0.019	1.997TyrGly: 1.997 ± 0.023	0.974TyrHis: 0.974 ± 0.019	1.617TyrIle: 1.617 ± 0.023	1.489TyrLys: 1.489 ± 0.017	2.999TyrLeu: 2.999 ± 0.032	0.808TyrMet: 0.808 ± 0.014	1.309TyrAsn: 1.309 ± 0.016	1.556TyrPro: 1.556 ± 0.023	1.358TyrGln: 1.358 ± 0.018	1.819TyrArg: 1.819 ± 0.024	1.991TyrSer: 1.991 ± 0.024	1.784TyrThr: 1.784 ± 0.021	1.859TyrVal: 1.859 ± 0.023	0.417TyrTrp: 0.417 ± 0.011	1.257TyrTyr: 1.257 ± 0.019	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 11037 proteins (4486539 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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