Amino acid dipepetide frequency for Carrot red leaf virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.658AlaAla: 2.658 ± 1.181
1.329AlaCys: 1.329 ± 0.684
0.664AlaAsp: 0.664 ± 0.385
3.322AlaGlu: 3.322 ± 0.759
3.322AlaPhe: 3.322 ± 0.616
4.983AlaGly: 4.983 ± 1.346
0.664AlaHis: 0.664 ± 0.662
2.658AlaIle: 2.658 ± 1.025
3.987AlaLys: 3.987 ± 1.363
6.645AlaLeu: 6.645 ± 1.649
1.661AlaMet: 1.661 ± 0.681
1.993AlaAsn: 1.993 ± 0.679
3.654AlaPro: 3.654 ± 0.677
2.658AlaGln: 2.658 ± 1.679
6.645AlaArg: 6.645 ± 1.174
2.99AlaSer: 2.99 ± 0.633
4.651AlaThr: 4.651 ± 0.7
1.993AlaVal: 1.993 ± 0.98
0.0AlaTrp: 0.0 ± 0.0
3.322AlaTyr: 3.322 ± 0.905
0.0AlaXaa: 0.0 ± 0.0
Cys
0.332CysAla: 0.332 ± 0.507
0.0CysCys: 0.0 ± 0.0
0.332CysAsp: 0.332 ± 0.247
3.322CysGlu: 3.322 ± 0.576
0.664CysPhe: 0.664 ± 0.662
1.329CysGly: 1.329 ± 0.746
0.332CysHis: 0.332 ± 0.507
0.664CysIle: 0.664 ± 0.485
0.332CysLys: 0.332 ± 0.507
2.658CysLeu: 2.658 ± 0.708
0.0CysMet: 0.0 ± 0.0
0.332CysAsn: 0.332 ± 0.316
0.997CysPro: 0.997 ± 0.483
0.0CysGln: 0.0 ± 0.0
0.664CysArg: 0.664 ± 0.342
1.661CysSer: 1.661 ± 0.659
0.997CysThr: 0.997 ± 0.49
1.329CysVal: 1.329 ± 0.684
0.0CysTrp: 0.0 ± 0.0
0.664CysTyr: 0.664 ± 0.342
0.0CysXaa: 0.0 ± 0.0
Asp
3.654AspAla: 3.654 ± 0.935
0.997AspCys: 0.997 ± 0.741
2.658AspAsp: 2.658 ± 0.657
3.987AspGlu: 3.987 ± 1.19
0.664AspPhe: 0.664 ± 0.565
3.654AspGly: 3.654 ± 0.637
0.664AspHis: 0.664 ± 0.493
1.993AspIle: 1.993 ± 0.814
2.99AspLys: 2.99 ± 0.886
3.987AspLeu: 3.987 ± 1.383
1.329AspMet: 1.329 ± 0.337
2.658AspAsn: 2.658 ± 1.785
2.658AspPro: 2.658 ± 1.128
1.661AspGln: 1.661 ± 0.329
1.661AspArg: 1.661 ± 0.897
3.654AspSer: 3.654 ± 1.302
0.997AspThr: 0.997 ± 0.55
1.329AspVal: 1.329 ± 0.512
0.997AspTrp: 0.997 ± 0.741
1.329AspTyr: 1.329 ± 1.128
0.0AspXaa: 0.0 ± 0.0
Glu
3.987GluAla: 3.987 ± 1.207
0.332GluCys: 0.332 ± 0.247
3.654GluAsp: 3.654 ± 1.356
3.654GluGlu: 3.654 ± 1.242
1.993GluPhe: 1.993 ± 0.753
3.987GluGly: 3.987 ± 1.607
0.664GluHis: 0.664 ± 0.286
2.326GluIle: 2.326 ± 0.451
2.99GluLys: 2.99 ± 0.76
6.977GluLeu: 6.977 ± 0.751
0.332GluMet: 0.332 ± 0.585
4.319GluAsn: 4.319 ± 0.626
2.326GluPro: 2.326 ± 1.466
2.658GluGln: 2.658 ± 0.933
1.993GluArg: 1.993 ± 0.679
4.651GluSer: 4.651 ± 1.526
1.993GluThr: 1.993 ± 0.738
4.319GluVal: 4.319 ± 0.947
0.997GluTrp: 0.997 ± 0.721
2.326GluTyr: 2.326 ± 0.932
0.0GluXaa: 0.0 ± 0.0
Phe
1.993PheAla: 1.993 ± 0.948
0.664PheCys: 0.664 ± 0.494
2.658PheAsp: 2.658 ± 0.675
2.99PheGlu: 2.99 ± 0.839
1.329PhePhe: 1.329 ± 0.385
3.654PheGly: 3.654 ± 1.017
1.993PheHis: 1.993 ± 0.592
0.664PheIle: 0.664 ± 0.565
2.326PheLys: 2.326 ± 0.695
3.654PheLeu: 3.654 ± 0.447
0.997PheMet: 0.997 ± 0.47
1.993PheAsn: 1.993 ± 0.76
0.997PhePro: 0.997 ± 0.265
1.993PheGln: 1.993 ± 0.52
2.326PheArg: 2.326 ± 0.687
4.319PheSer: 4.319 ± 0.541
1.993PheThr: 1.993 ± 0.966
2.326PheVal: 2.326 ± 0.729
0.332PheTrp: 0.332 ± 0.316
1.329PheTyr: 1.329 ± 1.517
0.0PheXaa: 0.0 ± 0.0
Gly
3.987GlyAla: 3.987 ± 1.556
0.664GlyCys: 0.664 ± 0.286
2.99GlyAsp: 2.99 ± 0.813
3.987GlyGlu: 3.987 ± 1.665
3.322GlyPhe: 3.322 ± 1.319
6.312GlyGly: 6.312 ± 1.938
2.658GlyHis: 2.658 ± 0.731
3.654GlyIle: 3.654 ± 1.243
6.312GlyLys: 6.312 ± 1.741
7.641GlyLeu: 7.641 ± 0.567
0.332GlyMet: 0.332 ± 0.316
3.322GlyAsn: 3.322 ± 1.017
3.322GlyPro: 3.322 ± 1.273
1.661GlyGln: 1.661 ± 0.89
4.319GlyArg: 4.319 ± 1.253
10.631GlySer: 10.631 ± 3.427
2.326GlyThr: 2.326 ± 0.821
3.654GlyVal: 3.654 ± 1.023
1.329GlyTrp: 1.329 ± 0.697
3.322GlyTyr: 3.322 ± 0.905
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.332HisCys: 0.332 ± 0.247
1.661HisAsp: 1.661 ± 1.435
1.329HisGlu: 1.329 ± 0.964
0.332HisPhe: 0.332 ± 0.316
1.661HisGly: 1.661 ± 0.681
0.332HisHis: 0.332 ± 0.507
0.664HisIle: 0.664 ± 0.286
0.332HisLys: 0.332 ± 0.247
0.664HisLeu: 0.664 ± 0.482
0.0HisMet: 0.0 ± 0.0
1.661HisAsn: 1.661 ± 0.963
2.326HisPro: 2.326 ± 0.492
1.661HisGln: 1.661 ± 0.976
1.329HisArg: 1.329 ± 0.746
5.648HisSer: 5.648 ± 1.48
0.664HisThr: 0.664 ± 0.342
1.993HisVal: 1.993 ± 0.412
0.0HisTrp: 0.0 ± 0.0
0.664HisTyr: 0.664 ± 0.493
0.0HisXaa: 0.0 ± 0.0
Ile
2.99IleAla: 2.99 ± 0.571
0.664IleCys: 0.664 ± 0.342
0.997IleAsp: 0.997 ± 0.431
2.658IleGlu: 2.658 ± 1.368
1.661IlePhe: 1.661 ± 0.808
1.993IleGly: 1.993 ± 0.966
1.993IleHis: 1.993 ± 0.437
2.326IleIle: 2.326 ± 0.844
2.99IleLys: 2.99 ± 0.707
2.99IleLeu: 2.99 ± 0.895
0.997IleMet: 0.997 ± 0.49
2.326IleAsn: 2.326 ± 0.754
4.319IlePro: 4.319 ± 1.023
1.661IleGln: 1.661 ± 1.069
1.993IleArg: 1.993 ± 0.967
4.983IleSer: 4.983 ± 1.025
2.658IleThr: 2.658 ± 1.065
1.329IleVal: 1.329 ± 0.657
1.661IleTrp: 1.661 ± 0.666
1.993IleTyr: 1.993 ± 0.406
0.0IleXaa: 0.0 ± 0.0
Lys
2.99LysAla: 2.99 ± 1.239
0.332LysCys: 0.332 ± 0.247
3.322LysAsp: 3.322 ± 1.019
2.326LysGlu: 2.326 ± 0.729
1.661LysPhe: 1.661 ± 1.194
2.326LysGly: 2.326 ± 0.451
1.661LysHis: 1.661 ± 0.808
6.312LysIle: 6.312 ± 1.53
0.332LysLys: 0.332 ± 0.341
8.306LysLeu: 8.306 ± 2.005
0.997LysMet: 0.997 ± 0.636
2.658LysAsn: 2.658 ± 0.751
5.648LysPro: 5.648 ± 1.255
3.987LysGln: 3.987 ± 1.059
3.987LysArg: 3.987 ± 1.457
4.651LysSer: 4.651 ± 1.013
1.993LysThr: 1.993 ± 0.53
1.329LysVal: 1.329 ± 0.684
0.997LysTrp: 0.997 ± 0.49
1.993LysTyr: 1.993 ± 0.379
0.332LysXaa: 0.332 ± 0.316
Leu
7.973LeuAla: 7.973 ± 1.844
3.654LeuCys: 3.654 ± 1.543
6.977LeuAsp: 6.977 ± 1.576
4.983LeuGlu: 4.983 ± 1.752
4.651LeuPhe: 4.651 ± 1.313
2.99LeuGly: 2.99 ± 0.953
1.993LeuHis: 1.993 ± 0.786
4.319LeuIle: 4.319 ± 0.855
3.987LeuLys: 3.987 ± 1.459
6.977LeuLeu: 6.977 ± 1.588
1.993LeuMet: 1.993 ± 0.857
1.661LeuAsn: 1.661 ± 0.503
5.316LeuPro: 5.316 ± 1.539
2.326LeuGln: 2.326 ± 0.975
4.319LeuArg: 4.319 ± 0.961
8.306LeuSer: 8.306 ± 0.979
6.977LeuThr: 6.977 ± 1.467
5.648LeuVal: 5.648 ± 0.982
3.322LeuTrp: 3.322 ± 0.294
1.661LeuTyr: 1.661 ± 0.905
0.0LeuXaa: 0.0 ± 0.0
Met
2.99MetAla: 2.99 ± 0.839
0.0MetCys: 0.0 ± 0.0
0.997MetAsp: 0.997 ± 0.799
1.661MetGlu: 1.661 ± 0.529
1.329MetPhe: 1.329 ± 0.473
2.658MetGly: 2.658 ± 0.524
0.0MetHis: 0.0 ± 0.0
1.329MetIle: 1.329 ± 0.684
0.0MetLys: 0.0 ± 0.0
0.664MetLeu: 0.664 ± 0.485
0.332MetMet: 0.332 ± 0.341
0.664MetAsn: 0.664 ± 0.286
0.0MetPro: 0.0 ± 0.0
0.664MetGln: 0.664 ± 0.342
0.664MetArg: 0.664 ± 0.493
1.661MetSer: 1.661 ± 0.362
1.329MetThr: 1.329 ± 0.697
1.661MetVal: 1.661 ± 0.439
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.329AsnAla: 1.329 ± 0.697
0.0AsnCys: 0.0 ± 0.0
1.993AsnAsp: 1.993 ± 1.525
1.661AsnGlu: 1.661 ± 0.524
2.99AsnPhe: 2.99 ± 0.904
6.645AsnGly: 6.645 ± 1.509
0.0AsnHis: 0.0 ± 0.0
2.326AsnIle: 2.326 ± 0.479
3.322AsnLys: 3.322 ± 0.8
4.983AsnLeu: 4.983 ± 1.438
1.661AsnMet: 1.661 ± 0.516
0.664AsnAsn: 0.664 ± 0.565
2.99AsnPro: 2.99 ± 0.736
2.326AsnGln: 2.326 ± 0.473
2.99AsnArg: 2.99 ± 0.99
4.651AsnSer: 4.651 ± 1.053
3.987AsnThr: 3.987 ± 0.982
1.661AsnVal: 1.661 ± 0.861
1.329AsnTrp: 1.329 ± 0.572
1.661AsnTyr: 1.661 ± 0.433
0.0AsnXaa: 0.0 ± 0.0
Pro
2.99ProAla: 2.99 ± 1.239
1.329ProCys: 1.329 ± 2.029
1.661ProAsp: 1.661 ± 0.513
4.651ProGlu: 4.651 ± 0.654
1.993ProPhe: 1.993 ± 0.738
3.654ProGly: 3.654 ± 1.095
1.329ProHis: 1.329 ± 0.724
1.661ProIle: 1.661 ± 0.364
4.651ProLys: 4.651 ± 1.064
2.658ProLeu: 2.658 ± 0.745
1.661ProMet: 1.661 ± 0.496
1.993ProAsn: 1.993 ± 1.195
4.983ProPro: 4.983 ± 1.659
2.99ProGln: 2.99 ± 0.794
3.654ProArg: 3.654 ± 1.541
7.309ProSer: 7.309 ± 1.411
3.654ProThr: 3.654 ± 1.404
4.651ProVal: 4.651 ± 1.309
0.997ProTrp: 0.997 ± 0.428
0.332ProTyr: 0.332 ± 0.507
0.0ProXaa: 0.0 ± 0.0
Gln
2.99GlnAla: 2.99 ± 0.571
0.0GlnCys: 0.0 ± 0.0
0.332GlnAsp: 0.332 ± 0.316
1.661GlnGlu: 1.661 ± 0.81
0.997GlnPhe: 0.997 ± 0.444
3.322GlnGly: 3.322 ± 0.736
0.664GlnHis: 0.664 ± 0.286
1.993GlnIle: 1.993 ± 0.948
3.654GlnLys: 3.654 ± 0.759
1.993GlnLeu: 1.993 ± 0.948
0.332GlnMet: 0.332 ± 0.29
4.319GlnAsn: 4.319 ± 0.741
1.661GlnPro: 1.661 ± 0.818
0.664GlnGln: 0.664 ± 0.392
1.993GlnArg: 1.993 ± 0.459
2.326GlnSer: 2.326 ± 0.728
3.987GlnThr: 3.987 ± 0.97
2.326GlnVal: 2.326 ± 0.628
1.661GlnTrp: 1.661 ± 0.362
0.664GlnTyr: 0.664 ± 0.493
0.0GlnXaa: 0.0 ± 0.0
Arg
4.319ArgAla: 4.319 ± 1.49
0.664ArgCys: 0.664 ± 0.562
1.329ArgAsp: 1.329 ± 0.487
2.658ArgGlu: 2.658 ± 1.145
1.993ArgPhe: 1.993 ± 0.759
5.316ArgGly: 5.316 ± 0.942
0.664ArgHis: 0.664 ± 0.392
1.993ArgIle: 1.993 ± 0.651
2.326ArgLys: 2.326 ± 0.685
5.648ArgLeu: 5.648 ± 1.663
0.997ArgMet: 0.997 ± 0.695
3.654ArgAsn: 3.654 ± 1.062
1.993ArgPro: 1.993 ± 0.995
0.664ArgGln: 0.664 ± 0.286
10.963ArgArg: 10.963 ± 4.008
2.99ArgSer: 2.99 ± 1.176
4.651ArgThr: 4.651 ± 2.149
4.319ArgVal: 4.319 ± 0.6
0.664ArgTrp: 0.664 ± 0.494
1.993ArgTyr: 1.993 ± 0.428
0.0ArgXaa: 0.0 ± 0.0
Ser
5.648SerAla: 5.648 ± 0.605
1.993SerCys: 1.993 ± 0.472
5.648SerAsp: 5.648 ± 1.844
3.654SerGlu: 3.654 ± 1.057
3.654SerPhe: 3.654 ± 1.365
9.967SerGly: 9.967 ± 1.617
2.658SerHis: 2.658 ± 0.938
2.99SerIle: 2.99 ± 0.403
4.319SerLys: 4.319 ± 1.425
8.638SerLeu: 8.638 ± 0.945
0.997SerMet: 0.997 ± 0.581
4.983SerAsn: 4.983 ± 1.127
3.322SerPro: 3.322 ± 1.058
4.983SerGln: 4.983 ± 1.088
5.98SerArg: 5.98 ± 1.696
9.635SerSer: 9.635 ± 2.084
6.312SerThr: 6.312 ± 1.227
4.651SerVal: 4.651 ± 1.647
2.658SerTrp: 2.658 ± 0.456
4.319SerTyr: 4.319 ± 0.685
0.0SerXaa: 0.0 ± 0.0
Thr
4.319ThrAla: 4.319 ± 0.541
2.326ThrCys: 2.326 ± 0.683
3.322ThrAsp: 3.322 ± 0.612
1.329ThrGlu: 1.329 ± 0.85
2.658ThrPhe: 2.658 ± 0.453
4.319ThrGly: 4.319 ± 0.773
1.329ThrHis: 1.329 ± 0.729
1.993ThrIle: 1.993 ± 0.437
4.983ThrLys: 4.983 ± 0.873
4.983ThrLeu: 4.983 ± 0.566
1.661ThrMet: 1.661 ± 0.496
2.99ThrAsn: 2.99 ± 1.135
6.977ThrPro: 6.977 ± 1.042
0.664ThrGln: 0.664 ± 0.342
1.329ThrArg: 1.329 ± 0.657
4.983ThrSer: 4.983 ± 0.985
5.316ThrThr: 5.316 ± 2.236
4.651ThrVal: 4.651 ± 0.937
0.332ThrTrp: 0.332 ± 0.247
1.661ThrTyr: 1.661 ± 0.508
0.0ThrXaa: 0.0 ± 0.0
Val
1.329ValAla: 1.329 ± 0.724
0.997ValCys: 0.997 ± 0.483
2.326ValAsp: 2.326 ± 0.685
4.319ValGlu: 4.319 ± 1.316
2.99ValPhe: 2.99 ± 0.651
3.654ValGly: 3.654 ± 0.765
1.661ValHis: 1.661 ± 0.681
2.658ValIle: 2.658 ± 0.715
1.993ValLys: 1.993 ± 0.448
5.648ValLeu: 5.648 ± 0.817
1.661ValMet: 1.661 ± 0.433
4.651ValAsn: 4.651 ± 0.64
3.322ValPro: 3.322 ± 1.16
2.658ValGln: 2.658 ± 0.643
0.997ValArg: 0.997 ± 0.444
5.98ValSer: 5.98 ± 1.084
3.654ValThr: 3.654 ± 1.079
7.641ValVal: 7.641 ± 1.715
0.0ValTrp: 0.0 ± 0.0
0.664ValTyr: 0.664 ± 0.286
0.0ValXaa: 0.0 ± 0.0
Trp
2.326TrpAla: 2.326 ± 0.554
0.332TrpCys: 0.332 ± 0.507
0.0TrpAsp: 0.0 ± 0.0
1.329TrpGlu: 1.329 ± 0.512
0.0TrpPhe: 0.0 ± 0.0
0.664TrpGly: 0.664 ± 0.485
0.664TrpHis: 0.664 ± 0.493
0.0TrpIle: 0.0 ± 0.0
1.993TrpLys: 1.993 ± 0.472
2.99TrpLeu: 2.99 ± 1.327
0.0TrpMet: 0.0 ± 0.0
0.332TrpAsn: 0.332 ± 0.316
0.997TrpPro: 0.997 ± 0.741
0.664TrpGln: 0.664 ± 0.342
0.664TrpArg: 0.664 ± 0.286
1.993TrpSer: 1.993 ± 0.428
1.661TrpThr: 1.661 ± 0.529
0.332TrpVal: 0.332 ± 0.247
0.0TrpTrp: 0.0 ± 0.0
0.332TrpTyr: 0.332 ± 0.37
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.997TyrAla: 0.997 ± 0.49
0.0TyrCys: 0.0 ± 0.0
0.0TyrAsp: 0.0 ± 0.0
1.329TyrGlu: 1.329 ± 0.34
2.326TyrPhe: 2.326 ± 0.483
2.658TyrGly: 2.658 ± 0.645
1.329TyrHis: 1.329 ± 0.697
2.658TyrIle: 2.658 ± 0.86
4.319TyrLys: 4.319 ± 0.884
1.329TyrLeu: 1.329 ± 0.487
0.332TyrMet: 0.332 ± 0.316
1.993TyrAsn: 1.993 ± 0.929
0.997TyrPro: 0.997 ± 0.483
0.997TyrGln: 0.997 ± 0.704
1.329TyrArg: 1.329 ± 0.929
3.987TyrSer: 3.987 ± 0.776
2.326TyrThr: 2.326 ± 0.454
1.329TyrVal: 1.329 ± 1.128
0.0TyrTrp: 0.0 ± 0.0
0.997TyrTyr: 0.997 ± 0.578
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.332XaaVal: 0.332 ± 0.316
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (3011 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski