Amino acid dipepetide frequency for Cacao swollen shoot Ghana M virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.446AlaAla: 4.446 ± 2.044
0.445AlaCys: 0.445 ± 0.21
2.223AlaAsp: 2.223 ± 0.856
4.446AlaGlu: 4.446 ± 1.712
4.002AlaPhe: 4.002 ± 1.107
2.223AlaGly: 2.223 ± 2.351
0.445AlaHis: 0.445 ± 1.258
5.336AlaIle: 5.336 ± 1.74
4.891AlaLys: 4.891 ± 3.446
4.002AlaLeu: 4.002 ± 4.286
1.334AlaMet: 1.334 ± 0.63
1.334AlaAsn: 1.334 ± 1.824
1.779AlaPro: 1.779 ± 0.839
3.557AlaGln: 3.557 ± 1.117
3.557AlaArg: 3.557 ± 0.985
4.446AlaSer: 4.446 ± 2.108
4.002AlaThr: 4.002 ± 1.019
3.557AlaVal: 3.557 ± 3.028
0.0AlaTrp: 0.0 ± 0.0
3.112AlaTyr: 3.112 ± 1.082
0.0AlaXaa: 0.0 ± 0.0
Cys
0.889CysAla: 0.889 ± 0.42
0.445CysCys: 0.445 ± 0.21
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.889CysPhe: 0.889 ± 0.42
0.889CysGly: 0.889 ± 1.231
0.445CysHis: 0.445 ± 0.21
0.889CysIle: 0.889 ± 0.42
2.668CysLys: 2.668 ± 1.259
0.889CysLeu: 0.889 ± 1.135
0.445CysMet: 0.445 ± 0.21
0.889CysAsn: 0.889 ± 0.42
0.445CysPro: 0.445 ± 0.21
0.889CysGln: 0.889 ± 0.42
0.0CysArg: 0.0 ± 0.0
0.889CysSer: 0.889 ± 0.42
0.445CysThr: 0.445 ± 0.21
0.889CysVal: 0.889 ± 0.42
0.445CysTrp: 0.445 ± 0.21
1.334CysTyr: 1.334 ± 0.63
0.0CysXaa: 0.0 ± 0.0
Asp
2.223AspAla: 2.223 ± 1.049
0.445AspCys: 0.445 ± 0.21
3.112AspAsp: 3.112 ± 1.469
4.891AspGlu: 4.891 ± 1.694
0.445AspPhe: 0.445 ± 0.21
2.668AspGly: 2.668 ± 1.031
0.889AspHis: 0.889 ± 1.231
2.223AspIle: 2.223 ± 1.049
2.223AspLys: 2.223 ± 1.049
4.446AspLeu: 4.446 ± 1.288
0.445AspMet: 0.445 ± 0.21
3.557AspAsn: 3.557 ± 1.117
4.446AspPro: 4.446 ± 1.253
3.557AspGln: 3.557 ± 1.094
3.112AspArg: 3.112 ± 3.224
2.223AspSer: 2.223 ± 1.551
3.557AspThr: 3.557 ± 1.679
1.779AspVal: 1.779 ± 0.839
0.445AspTrp: 0.445 ± 0.21
3.112AspTyr: 3.112 ± 1.469
0.0AspXaa: 0.0 ± 0.0
Glu
3.557GluAla: 3.557 ± 1.117
0.889GluCys: 0.889 ± 0.42
6.225GluAsp: 6.225 ± 1.955
10.227GluGlu: 10.227 ± 2.489
1.779GluPhe: 1.779 ± 0.839
5.78GluGly: 5.78 ± 1.735
1.779GluHis: 1.779 ± 0.839
5.336GluIle: 5.336 ± 1.685
7.114GluLys: 7.114 ± 5.653
5.78GluLeu: 5.78 ± 1.769
0.445GluMet: 0.445 ± 0.21
3.557GluAsn: 3.557 ± 1.063
1.779GluPro: 1.779 ± 1.055
4.891GluGln: 4.891 ± 1.503
4.891GluArg: 4.891 ± 1.995
7.114GluSer: 7.114 ± 3.756
5.336GluThr: 5.336 ± 1.811
4.891GluVal: 4.891 ± 1.92
1.779GluTrp: 1.779 ± 0.928
1.779GluTyr: 1.779 ± 0.928
0.0GluXaa: 0.0 ± 0.0
Phe
2.668PheAla: 2.668 ± 1.259
0.889PheCys: 0.889 ± 0.42
2.223PheAsp: 2.223 ± 1.531
1.334PheGlu: 1.334 ± 0.63
0.889PhePhe: 0.889 ± 0.42
0.889PheGly: 0.889 ± 0.42
1.779PheHis: 1.779 ± 0.839
2.223PheIle: 2.223 ± 0.892
4.002PheLys: 4.002 ± 1.019
1.779PheLeu: 1.779 ± 0.839
1.779PheMet: 1.779 ± 0.839
1.334PheAsn: 1.334 ± 0.63
0.889PhePro: 0.889 ± 0.42
0.445PheGln: 0.445 ± 0.21
2.668PheArg: 2.668 ± 1.368
3.112PheSer: 3.112 ± 1.469
0.445PheThr: 0.445 ± 0.21
1.334PheVal: 1.334 ± 0.63
0.445PheTrp: 0.445 ± 0.21
1.334PheTyr: 1.334 ± 0.63
0.0PheXaa: 0.0 ± 0.0
Gly
2.223GlyAla: 2.223 ± 1.022
0.889GlyCys: 0.889 ± 0.42
2.668GlyAsp: 2.668 ± 1.259
2.668GlyGlu: 2.668 ± 1.031
1.779GlyPhe: 1.779 ± 2.27
1.334GlyGly: 1.334 ± 0.63
1.779GlyHis: 1.779 ± 0.839
4.446GlyIle: 4.446 ± 2.192
4.446GlyLys: 4.446 ± 0.935
4.446GlyLeu: 4.446 ± 0.957
0.889GlyMet: 0.889 ± 0.42
3.557GlyAsn: 3.557 ± 1.063
1.334GlyPro: 1.334 ± 0.63
1.334GlyGln: 1.334 ± 1.007
4.891GlyArg: 4.891 ± 0.939
1.779GlySer: 1.779 ± 0.839
5.336GlyThr: 5.336 ± 1.74
3.112GlyVal: 3.112 ± 0.896
1.334GlyTrp: 1.334 ± 0.63
3.557GlyTyr: 3.557 ± 1.679
0.0GlyXaa: 0.0 ± 0.0
His
0.889HisAla: 0.889 ± 0.42
0.445HisCys: 0.445 ± 0.21
0.889HisAsp: 0.889 ± 0.42
1.334HisGlu: 1.334 ± 1.007
1.334HisPhe: 1.334 ± 1.127
1.779HisGly: 1.779 ± 0.839
0.445HisHis: 0.445 ± 0.21
2.668HisIle: 2.668 ± 1.259
1.334HisLys: 1.334 ± 0.63
1.779HisLeu: 1.779 ± 1.646
0.889HisMet: 0.889 ± 0.42
1.334HisAsn: 1.334 ± 1.007
0.0HisPro: 0.0 ± 0.0
1.334HisGln: 1.334 ± 0.63
2.223HisArg: 2.223 ± 1.049
0.445HisSer: 0.445 ± 0.21
1.334HisThr: 1.334 ± 1.007
0.889HisVal: 0.889 ± 0.42
0.889HisTrp: 0.889 ± 0.42
0.445HisTyr: 0.445 ± 0.21
0.0HisXaa: 0.0 ± 0.0
Ile
5.336IleAla: 5.336 ± 0.87
1.779IleCys: 1.779 ± 0.911
3.112IleAsp: 3.112 ± 1.469
4.446IleGlu: 4.446 ± 2.108
3.112IlePhe: 3.112 ± 0.965
3.112IleGly: 3.112 ± 1.469
2.223IleHis: 2.223 ± 0.892
4.002IleIle: 4.002 ± 2.067
6.225IleLys: 6.225 ± 1.134
7.114IleLeu: 7.114 ± 2.548
0.445IleMet: 0.445 ± 0.21
1.779IleAsn: 1.779 ± 1.646
4.446IlePro: 4.446 ± 2.044
4.446IleGln: 4.446 ± 1.34
2.668IleArg: 2.668 ± 1.259
3.557IleSer: 3.557 ± 1.057
4.002IleThr: 4.002 ± 1.107
3.112IleVal: 3.112 ± 0.965
0.445IleTrp: 0.445 ± 0.21
0.889IleTyr: 0.889 ± 0.42
0.0IleXaa: 0.0 ± 0.0
Lys
2.668LysAla: 2.668 ± 3.405
1.334LysCys: 1.334 ± 0.63
4.002LysAsp: 4.002 ± 3.022
7.559LysGlu: 7.559 ± 2.54
1.334LysPhe: 1.334 ± 0.63
3.557LysGly: 3.557 ± 0.985
3.557LysHis: 3.557 ± 1.063
3.112LysIle: 3.112 ± 1.916
7.559LysLys: 7.559 ± 3.746
5.78LysLeu: 5.78 ± 4.337
3.112LysMet: 3.112 ± 1.418
3.557LysAsn: 3.557 ± 1.057
3.557LysPro: 3.557 ± 1.063
4.446LysGln: 4.446 ± 4.773
6.225LysArg: 6.225 ± 1.826
4.891LysSer: 4.891 ± 1.92
2.223LysThr: 2.223 ± 1.049
3.112LysVal: 3.112 ± 0.965
0.445LysTrp: 0.445 ± 0.21
1.334LysTyr: 1.334 ± 0.63
0.0LysXaa: 0.0 ± 0.0
Leu
8.004LeuAla: 8.004 ± 8.655
1.334LeuCys: 1.334 ± 1.127
3.112LeuAsp: 3.112 ± 2.365
8.893LeuGlu: 8.893 ± 4.829
2.223LeuPhe: 2.223 ± 1.049
5.336LeuGly: 5.336 ± 1.811
1.779LeuHis: 1.779 ± 1.055
3.557LeuIle: 3.557 ± 1.822
5.78LeuLys: 5.78 ± 1.687
5.336LeuLeu: 5.336 ± 3.227
0.889LeuMet: 0.889 ± 0.42
1.334LeuAsn: 1.334 ± 0.63
4.002LeuPro: 4.002 ± 1.284
4.891LeuGln: 4.891 ± 2.075
4.002LeuArg: 4.002 ± 1.284
7.114LeuSer: 7.114 ± 1.528
4.002LeuThr: 4.002 ± 1.019
4.446LeuVal: 4.446 ± 1.34
0.445LeuTrp: 0.445 ± 0.21
3.557LeuTyr: 3.557 ± 1.117
0.0LeuXaa: 0.0 ± 0.0
Met
1.779MetAla: 1.779 ± 0.839
0.445MetCys: 0.445 ± 0.21
0.889MetAsp: 0.889 ± 0.42
2.668MetGlu: 2.668 ± 1.031
0.889MetPhe: 0.889 ± 0.42
0.445MetGly: 0.445 ± 0.21
0.0MetHis: 0.0 ± 0.0
1.334MetIle: 1.334 ± 0.63
1.334MetLys: 1.334 ± 0.63
1.779MetLeu: 1.779 ± 0.839
1.334MetMet: 1.334 ± 0.63
1.334MetAsn: 1.334 ± 0.63
1.779MetPro: 1.779 ± 0.839
0.889MetGln: 0.889 ± 0.42
0.445MetArg: 0.445 ± 0.21
0.889MetSer: 0.889 ± 1.12
3.112MetThr: 3.112 ± 0.896
1.779MetVal: 1.779 ± 0.839
0.0MetTrp: 0.0 ± 0.0
0.445MetTyr: 0.445 ± 0.21
0.0MetXaa: 0.0 ± 0.0
Asn
1.334AsnAla: 1.334 ± 1.127
0.889AsnCys: 0.889 ± 0.42
1.334AsnAsp: 1.334 ± 0.63
1.779AsnGlu: 1.779 ± 0.839
0.889AsnPhe: 0.889 ± 0.42
2.223AsnGly: 2.223 ± 1.049
0.889AsnHis: 0.889 ± 0.42
2.223AsnIle: 2.223 ± 1.022
2.668AsnLys: 2.668 ± 0.905
5.336AsnLeu: 5.336 ± 4.478
1.334AsnMet: 1.334 ± 0.63
0.889AsnAsn: 0.889 ± 1.135
2.223AsnPro: 2.223 ± 1.049
4.002AsnGln: 4.002 ± 1.497
1.334AsnArg: 1.334 ± 1.007
1.334AsnSer: 1.334 ± 1.007
3.557AsnThr: 3.557 ± 1.679
1.334AsnVal: 1.334 ± 1.007
0.445AsnTrp: 0.445 ± 0.21
3.112AsnTyr: 3.112 ± 1.082
0.0AsnXaa: 0.0 ± 0.0
Pro
4.002ProAla: 4.002 ± 1.107
0.445ProCys: 0.445 ± 0.21
2.668ProAsp: 2.668 ± 1.259
5.336ProGlu: 5.336 ± 0.967
0.445ProPhe: 0.445 ± 0.21
1.779ProGly: 1.779 ± 1.055
0.889ProHis: 0.889 ± 0.42
3.112ProIle: 3.112 ± 1.082
3.112ProLys: 3.112 ± 1.221
3.112ProLeu: 3.112 ± 0.965
1.334ProMet: 1.334 ± 0.827
2.668ProAsn: 2.668 ± 1.259
4.446ProPro: 4.446 ± 2.099
1.779ProGln: 1.779 ± 0.839
2.223ProArg: 2.223 ± 1.049
2.668ProSer: 2.668 ± 1.259
2.223ProThr: 2.223 ± 1.551
2.668ProVal: 2.668 ± 1.259
0.889ProTrp: 0.889 ± 0.42
1.779ProTyr: 1.779 ± 1.723
0.0ProXaa: 0.0 ± 0.0
Gln
3.557GlnAla: 3.557 ± 1.707
0.445GlnCys: 0.445 ± 0.21
2.223GlnAsp: 2.223 ± 1.022
7.114GlnGlu: 7.114 ± 1.421
1.779GlnPhe: 1.779 ± 0.928
4.446GlnGly: 4.446 ± 0.957
0.0GlnHis: 0.0 ± 0.0
6.225GlnIle: 6.225 ± 1.801
3.112GlnLys: 3.112 ± 1.916
6.225GlnLeu: 6.225 ± 2.83
1.334GlnMet: 1.334 ± 1.435
2.668GlnAsn: 2.668 ± 2.015
3.112GlnPro: 3.112 ± 1.176
6.225GlnGln: 6.225 ± 1.917
1.779GlnArg: 1.779 ± 0.839
2.668GlnSer: 2.668 ± 1.259
3.112GlnThr: 3.112 ± 1.469
3.557GlnVal: 3.557 ± 1.679
2.223GlnTrp: 2.223 ± 0.892
1.779GlnTyr: 1.779 ± 0.839
0.0GlnXaa: 0.0 ± 0.0
Arg
3.112ArgAla: 3.112 ± 3.58
0.0ArgCys: 0.0 ± 0.0
3.557ArgAsp: 3.557 ± 3.476
4.002ArgGlu: 4.002 ± 0.996
1.779ArgPhe: 1.779 ± 0.839
2.668ArgGly: 2.668 ± 1.031
0.889ArgHis: 0.889 ± 0.42
4.891ArgIle: 4.891 ± 1.92
1.334ArgLys: 1.334 ± 0.63
6.225ArgLeu: 6.225 ± 1.144
2.223ArgMet: 2.223 ± 1.049
2.668ArgAsn: 2.668 ± 1.259
2.223ArgPro: 2.223 ± 1.049
3.112ArgGln: 3.112 ± 1.243
4.891ArgArg: 4.891 ± 1.575
4.446ArgSer: 4.446 ± 1.712
3.112ArgThr: 3.112 ± 1.082
5.336ArgVal: 5.336 ± 2.783
1.779ArgTrp: 1.779 ± 0.928
0.889ArgTyr: 0.889 ± 0.42
0.0ArgXaa: 0.0 ± 0.0
Ser
0.889SerAla: 0.889 ± 0.42
0.445SerCys: 0.445 ± 0.21
4.446SerAsp: 4.446 ± 2.002
5.78SerGlu: 5.78 ± 2.732
1.334SerPhe: 1.334 ± 0.63
3.557SerGly: 3.557 ± 0.985
1.334SerHis: 1.334 ± 1.007
4.446SerIle: 4.446 ± 1.34
5.336SerLys: 5.336 ± 1.813
4.891SerLeu: 4.891 ± 2.455
1.334SerMet: 1.334 ± 0.63
1.334SerAsn: 1.334 ± 0.63
2.223SerPro: 2.223 ± 0.856
4.002SerGln: 4.002 ± 1.191
5.336SerArg: 5.336 ± 2.14
4.891SerSer: 4.891 ± 3.257
4.891SerThr: 4.891 ± 4.157
3.557SerVal: 3.557 ± 2.111
0.445SerTrp: 0.445 ± 0.21
1.334SerTyr: 1.334 ± 1.903
0.0SerXaa: 0.0 ± 0.0
Thr
5.78ThrAla: 5.78 ± 0.662
1.334ThrCys: 1.334 ± 0.63
2.668ThrAsp: 2.668 ± 1.259
4.446ThrGlu: 4.446 ± 0.957
1.779ThrPhe: 1.779 ± 0.839
4.446ThrGly: 4.446 ± 2.099
2.223ThrHis: 2.223 ± 1.049
4.002ThrIle: 4.002 ± 1.889
2.668ThrLys: 2.668 ± 0.851
3.112ThrLeu: 3.112 ± 1.082
1.334ThrMet: 1.334 ± 0.63
0.889ThrAsn: 0.889 ± 1.12
4.002ThrPro: 4.002 ± 1.755
4.446ThrGln: 4.446 ± 2.002
4.002ThrArg: 4.002 ± 0.969
2.668ThrSer: 2.668 ± 2.669
6.67ThrThr: 6.67 ± 2.354
5.336ThrVal: 5.336 ± 0.87
0.889ThrTrp: 0.889 ± 0.42
1.779ThrTyr: 1.779 ± 0.839
0.0ThrXaa: 0.0 ± 0.0
Val
3.112ValAla: 3.112 ± 1.082
0.445ValCys: 0.445 ± 0.21
1.779ValAsp: 1.779 ± 0.839
4.446ValGlu: 4.446 ± 2.928
4.446ValPhe: 4.446 ± 1.34
4.002ValGly: 4.002 ± 0.996
1.334ValHis: 1.334 ± 0.63
2.668ValIle: 2.668 ± 0.905
4.446ValLys: 4.446 ± 1.34
3.112ValLeu: 3.112 ± 1.469
1.334ValMet: 1.334 ± 0.63
1.334ValAsn: 1.334 ± 1.007
2.668ValPro: 2.668 ± 0.851
4.002ValGln: 4.002 ± 2.322
2.668ValArg: 2.668 ± 1.259
2.668ValSer: 2.668 ± 3.883
4.891ValThr: 4.891 ± 1.866
1.779ValVal: 1.779 ± 0.839
0.889ValTrp: 0.889 ± 0.42
1.779ValTyr: 1.779 ± 0.839
0.0ValXaa: 0.0 ± 0.0
Trp
0.445TrpAla: 0.445 ± 0.21
0.0TrpCys: 0.0 ± 0.0
0.889TrpAsp: 0.889 ± 0.42
1.779TrpGlu: 1.779 ± 0.928
0.445TrpPhe: 0.445 ± 0.21
0.445TrpGly: 0.445 ± 0.21
0.0TrpHis: 0.0 ± 0.0
1.334TrpIle: 1.334 ± 0.63
0.445TrpLys: 0.445 ± 0.21
1.779TrpLeu: 1.779 ± 0.839
0.445TrpMet: 0.445 ± 0.21
0.0TrpAsn: 0.0 ± 0.0
0.889TrpPro: 0.889 ± 0.42
2.223TrpGln: 2.223 ± 1.049
0.445TrpArg: 0.445 ± 0.21
0.889TrpSer: 0.889 ± 0.42
0.889TrpThr: 0.889 ± 0.42
0.889TrpVal: 0.889 ± 1.12
0.445TrpTrp: 0.445 ± 0.21
0.445TrpTyr: 0.445 ± 1.258
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.223TyrAla: 2.223 ± 1.022
1.334TyrCys: 1.334 ± 0.63
1.779TyrAsp: 1.779 ± 1.055
1.779TyrGlu: 1.779 ± 0.928
0.889TyrPhe: 0.889 ± 0.42
2.223TyrGly: 2.223 ± 0.856
0.0TyrHis: 0.0 ± 0.0
2.223TyrIle: 2.223 ± 1.049
2.668TyrLys: 2.668 ± 1.39
3.112TyrLeu: 3.112 ± 0.965
0.445TyrMet: 0.445 ± 0.21
3.112TyrAsn: 3.112 ± 1.469
1.779TyrPro: 1.779 ± 1.055
3.112TyrGln: 3.112 ± 0.896
1.779TyrArg: 1.779 ± 0.839
3.112TyrSer: 3.112 ± 1.082
1.334TyrThr: 1.334 ± 0.63
0.445TyrVal: 0.445 ± 0.21
0.445TyrTrp: 0.445 ± 0.21
0.889TyrTyr: 0.889 ± 0.42
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (2250 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski