Amino acid dipepetide frequency for Citrus leprosis virus N

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.716AlaAla: 4.716 ± 2.584
0.832AlaCys: 0.832 ± 0.47
2.497AlaAsp: 2.497 ± 1.442
3.883AlaGlu: 3.883 ± 1.003
1.387AlaPhe: 1.387 ± 0.626
1.664AlaGly: 1.664 ± 0.816
1.942AlaHis: 1.942 ± 1.249
4.993AlaIle: 4.993 ± 1.328
2.774AlaLys: 2.774 ± 1.229
2.774AlaLeu: 2.774 ± 1.036
0.555AlaMet: 0.555 ± 0.773
1.11AlaAsn: 1.11 ± 0.391
3.329AlaPro: 3.329 ± 2.37
1.664AlaGln: 1.664 ± 0.695
2.219AlaArg: 2.219 ± 0.922
6.935AlaSer: 6.935 ± 1.259
3.606AlaThr: 3.606 ± 0.844
4.161AlaVal: 4.161 ± 1.278
1.387AlaTrp: 1.387 ± 0.519
2.497AlaTyr: 2.497 ± 0.501
0.0AlaXaa: 0.0 ± 0.0
Cys
1.387CysAla: 1.387 ± 0.557
0.0CysCys: 0.0 ± 0.0
1.664CysAsp: 1.664 ± 0.701
1.11CysGlu: 1.11 ± 0.337
1.11CysPhe: 1.11 ± 0.882
0.832CysGly: 0.832 ± 0.588
0.277CysHis: 0.277 ± 0.169
1.942CysIle: 1.942 ± 0.549
1.942CysLys: 1.942 ± 0.842
1.387CysLeu: 1.387 ± 0.41
0.555CysMet: 0.555 ± 0.338
1.11CysAsn: 1.11 ± 0.472
0.277CysPro: 0.277 ± 0.169
1.387CysGln: 1.387 ± 0.872
0.277CysArg: 0.277 ± 0.377
1.387CysSer: 1.387 ± 0.381
0.555CysThr: 0.555 ± 0.376
1.11CysVal: 1.11 ± 0.337
0.0CysTrp: 0.0 ± 0.0
0.555CysTyr: 0.555 ± 0.305
0.0CysXaa: 0.0 ± 0.0
Asp
2.497AspAla: 2.497 ± 0.425
1.11AspCys: 1.11 ± 0.307
3.329AspAsp: 3.329 ± 1.534
3.606AspGlu: 3.606 ± 1.634
1.11AspPhe: 1.11 ± 0.307
3.329AspGly: 3.329 ± 1.219
3.051AspHis: 3.051 ± 1.088
4.716AspIle: 4.716 ± 1.155
2.497AspLys: 2.497 ± 0.885
7.49AspLeu: 7.49 ± 0.488
1.942AspMet: 1.942 ± 0.598
2.219AspAsn: 2.219 ± 0.808
3.329AspPro: 3.329 ± 0.971
1.942AspGln: 1.942 ± 0.857
1.942AspArg: 1.942 ± 0.584
3.606AspSer: 3.606 ± 0.597
4.161AspThr: 4.161 ± 0.802
3.606AspVal: 3.606 ± 1.048
0.555AspTrp: 0.555 ± 0.376
2.219AspTyr: 2.219 ± 0.402
0.0AspXaa: 0.0 ± 0.0
Glu
2.774GluAla: 2.774 ± 0.669
0.555GluCys: 0.555 ± 0.488
3.606GluAsp: 3.606 ± 0.787
4.993GluGlu: 4.993 ± 0.784
1.387GluPhe: 1.387 ± 0.58
3.606GluGly: 3.606 ± 1.168
2.774GluHis: 2.774 ± 1.083
3.606GluIle: 3.606 ± 0.645
3.606GluLys: 3.606 ± 1.345
3.329GluLeu: 3.329 ± 1.325
3.051GluMet: 3.051 ± 0.532
0.832GluAsn: 0.832 ± 0.397
1.387GluPro: 1.387 ± 0.58
0.277GluGln: 0.277 ± 0.477
2.497GluArg: 2.497 ± 1.044
4.438GluSer: 4.438 ± 1.289
3.051GluThr: 3.051 ± 0.542
4.161GluVal: 4.161 ± 1.102
1.11GluTrp: 1.11 ± 0.447
1.387GluTyr: 1.387 ± 0.518
0.0GluXaa: 0.0 ± 0.0
Phe
0.832PheAla: 0.832 ± 0.47
0.832PheCys: 0.832 ± 0.489
0.555PheAsp: 0.555 ± 0.292
1.664PheGlu: 1.664 ± 0.455
1.11PhePhe: 1.11 ± 0.337
1.11PheGly: 1.11 ± 0.337
1.11PheHis: 1.11 ± 0.446
0.832PheIle: 0.832 ± 0.468
2.497PheLys: 2.497 ± 0.905
3.606PheLeu: 3.606 ± 0.854
0.832PheMet: 0.832 ± 0.354
1.942PheAsn: 1.942 ± 0.768
2.219PhePro: 2.219 ± 0.83
0.832PheGln: 0.832 ± 0.397
1.387PheArg: 1.387 ± 0.626
1.664PheSer: 1.664 ± 0.797
2.219PheThr: 2.219 ± 0.635
1.942PheVal: 1.942 ± 0.696
0.832PheTrp: 0.832 ± 0.676
0.832PheTyr: 0.832 ± 0.507
0.0PheXaa: 0.0 ± 0.0
Gly
2.497GlyAla: 2.497 ± 1.321
1.11GlyCys: 1.11 ± 0.548
4.993GlyAsp: 4.993 ± 0.896
3.883GlyGlu: 3.883 ± 1.183
1.942GlyPhe: 1.942 ± 0.597
6.103GlyGly: 6.103 ± 1.487
1.11GlyHis: 1.11 ± 0.472
5.548GlyIle: 5.548 ± 1.416
3.051GlyLys: 3.051 ± 0.545
6.657GlyLeu: 6.657 ± 1.238
2.497GlyMet: 2.497 ± 1.306
3.051GlyAsn: 3.051 ± 0.78
3.051GlyPro: 3.051 ± 1.119
1.387GlyGln: 1.387 ± 0.419
4.716GlyArg: 4.716 ± 1.687
4.716GlySer: 4.716 ± 1.233
2.774GlyThr: 2.774 ± 1.27
2.774GlyVal: 2.774 ± 0.567
0.555GlyTrp: 0.555 ± 0.292
1.387GlyTyr: 1.387 ± 0.876
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.277HisCys: 0.277 ± 0.386
1.942HisAsp: 1.942 ± 0.819
1.664HisGlu: 1.664 ± 0.613
0.277HisPhe: 0.277 ± 0.169
2.774HisGly: 2.774 ± 0.32
1.664HisHis: 1.664 ± 0.823
1.387HisIle: 1.387 ± 0.437
1.11HisLys: 1.11 ± 0.472
5.825HisLeu: 5.825 ± 1.56
0.832HisMet: 0.832 ± 0.489
1.942HisAsn: 1.942 ± 0.817
2.497HisPro: 2.497 ± 0.449
1.11HisGln: 1.11 ± 0.523
1.387HisArg: 1.387 ± 0.519
1.664HisSer: 1.664 ± 0.302
0.555HisThr: 0.555 ± 0.292
1.664HisVal: 1.664 ± 0.479
0.277HisTrp: 0.277 ± 0.169
0.555HisTyr: 0.555 ± 0.292
0.0HisXaa: 0.0 ± 0.0
Ile
4.161IleAla: 4.161 ± 1.463
1.387IleCys: 1.387 ± 0.355
4.438IleAsp: 4.438 ± 1.176
0.555IleGlu: 0.555 ± 0.548
1.664IlePhe: 1.664 ± 0.479
3.329IleGly: 3.329 ± 0.734
1.942IleHis: 1.942 ± 0.545
6.935IleIle: 6.935 ± 1.393
3.883IleLys: 3.883 ± 1.327
5.825IleLeu: 5.825 ± 2.605
3.329IleMet: 3.329 ± 0.832
3.051IleAsn: 3.051 ± 1.164
2.497IlePro: 2.497 ± 1.352
2.497IleGln: 2.497 ± 1.047
4.993IleArg: 4.993 ± 2.061
6.935IleSer: 6.935 ± 2.552
7.49IleThr: 7.49 ± 1.922
3.883IleVal: 3.883 ± 0.914
2.497IleTrp: 2.497 ± 0.67
2.774IleTyr: 2.774 ± 0.82
0.0IleXaa: 0.0 ± 0.0
Lys
3.329LysAla: 3.329 ± 1.659
0.832LysCys: 0.832 ± 0.758
3.051LysAsp: 3.051 ± 0.938
3.883LysGlu: 3.883 ± 0.994
1.664LysPhe: 1.664 ± 0.461
2.497LysGly: 2.497 ± 0.72
2.497LysHis: 2.497 ± 0.648
4.438LysIle: 4.438 ± 1.586
2.774LysLys: 2.774 ± 0.981
3.329LysLeu: 3.329 ± 0.99
1.11LysMet: 1.11 ± 0.417
3.606LysAsn: 3.606 ± 1.323
2.219LysPro: 2.219 ± 0.528
2.219LysGln: 2.219 ± 0.402
3.329LysArg: 3.329 ± 0.953
4.161LysSer: 4.161 ± 1.156
4.716LysThr: 4.716 ± 1.54
3.051LysVal: 3.051 ± 0.919
1.11LysTrp: 1.11 ± 0.536
1.664LysTyr: 1.664 ± 0.551
0.0LysXaa: 0.0 ± 0.0
Leu
5.548LeuAla: 5.548 ± 0.965
1.942LeuCys: 1.942 ± 0.882
3.606LeuAsp: 3.606 ± 0.946
5.548LeuGlu: 5.548 ± 1.391
3.329LeuPhe: 3.329 ± 1.014
5.825LeuGly: 5.825 ± 1.387
1.664LeuHis: 1.664 ± 0.615
6.103LeuIle: 6.103 ± 1.453
5.27LeuLys: 5.27 ± 1.13
6.103LeuLeu: 6.103 ± 1.277
3.329LeuMet: 3.329 ± 1.102
3.329LeuAsn: 3.329 ± 0.993
2.774LeuPro: 2.774 ± 0.553
2.219LeuGln: 2.219 ± 0.633
4.993LeuArg: 4.993 ± 1.079
11.096LeuSer: 11.096 ± 1.807
4.438LeuThr: 4.438 ± 1.227
6.38LeuVal: 6.38 ± 1.739
0.832LeuTrp: 0.832 ± 0.588
3.051LeuTyr: 3.051 ± 1.112
0.0LeuXaa: 0.0 ± 0.0
Met
2.219MetAla: 2.219 ± 0.782
0.555MetCys: 0.555 ± 0.509
2.774MetAsp: 2.774 ± 0.825
2.219MetGlu: 2.219 ± 0.63
1.387MetPhe: 1.387 ± 0.662
3.606MetGly: 3.606 ± 1.611
0.277MetHis: 0.277 ± 0.169
3.606MetIle: 3.606 ± 1.492
0.832MetLys: 0.832 ± 0.354
1.942MetLeu: 1.942 ± 0.752
3.606MetMet: 3.606 ± 0.701
1.387MetAsn: 1.387 ± 0.55
0.555MetPro: 0.555 ± 0.595
0.832MetGln: 0.832 ± 0.354
2.497MetArg: 2.497 ± 0.67
4.438MetSer: 4.438 ± 0.925
3.051MetThr: 3.051 ± 0.683
2.219MetVal: 2.219 ± 0.782
0.277MetTrp: 0.277 ± 0.169
1.387MetTyr: 1.387 ± 0.381
0.0MetXaa: 0.0 ± 0.0
Asn
1.387AsnAla: 1.387 ± 1.347
0.0AsnCys: 0.0 ± 0.0
2.497AsnAsp: 2.497 ± 1.082
2.219AsnGlu: 2.219 ± 0.748
0.0AsnPhe: 0.0 ± 0.0
1.387AsnGly: 1.387 ± 0.922
0.832AsnHis: 0.832 ± 0.507
3.606AsnIle: 3.606 ± 0.72
3.606AsnLys: 3.606 ± 1.606
2.774AsnLeu: 2.774 ± 0.669
3.883AsnMet: 3.883 ± 1.764
1.387AsnAsn: 1.387 ± 0.662
3.329AsnPro: 3.329 ± 0.93
1.387AsnGln: 1.387 ± 0.589
2.497AsnArg: 2.497 ± 1.251
1.11AsnSer: 1.11 ± 0.523
2.774AsnThr: 2.774 ± 0.523
2.219AsnVal: 2.219 ± 1.012
0.555AsnTrp: 0.555 ± 0.292
2.219AsnTyr: 2.219 ± 0.84
0.0AsnXaa: 0.0 ± 0.0
Pro
4.161ProAla: 4.161 ± 1.477
0.832ProCys: 0.832 ± 0.468
3.606ProAsp: 3.606 ± 1.231
1.664ProGlu: 1.664 ± 0.935
1.942ProPhe: 1.942 ± 0.705
2.774ProGly: 2.774 ± 1.829
0.832ProHis: 0.832 ± 0.47
3.051ProIle: 3.051 ± 0.5
2.774ProLys: 2.774 ± 0.605
5.548ProLeu: 5.548 ± 0.824
1.664ProMet: 1.664 ± 0.612
1.387ProAsn: 1.387 ± 0.597
3.606ProPro: 3.606 ± 2.638
0.832ProGln: 0.832 ± 0.895
2.219ProArg: 2.219 ± 0.633
3.051ProSer: 3.051 ± 1.656
2.219ProThr: 2.219 ± 0.906
4.438ProVal: 4.438 ± 0.824
0.555ProTrp: 0.555 ± 0.322
1.387ProTyr: 1.387 ± 0.355
0.0ProXaa: 0.0 ± 0.0
Gln
1.942GlnAla: 1.942 ± 1.0
1.11GlnCys: 1.11 ± 0.506
1.387GlnAsp: 1.387 ± 0.577
1.11GlnGlu: 1.11 ± 0.472
0.0GlnPhe: 0.0 ± 0.0
2.774GlnGly: 2.774 ± 0.673
1.387GlnHis: 1.387 ± 0.949
2.497GlnIle: 2.497 ± 0.808
2.774GlnLys: 2.774 ± 0.7
1.664GlnLeu: 1.664 ± 0.808
1.664GlnMet: 1.664 ± 0.558
0.832GlnAsn: 0.832 ± 0.468
0.832GlnPro: 0.832 ± 0.507
1.11GlnGln: 1.11 ± 0.611
0.555GlnArg: 0.555 ± 0.452
2.219GlnSer: 2.219 ± 1.329
1.387GlnThr: 1.387 ± 0.8
2.219GlnVal: 2.219 ± 0.294
0.0GlnTrp: 0.0 ± 0.0
1.11GlnTyr: 1.11 ± 1.294
0.0GlnXaa: 0.0 ± 0.0
Arg
3.883ArgAla: 3.883 ± 0.977
0.832ArgCys: 0.832 ± 0.307
3.051ArgAsp: 3.051 ± 1.229
2.497ArgGlu: 2.497 ± 0.975
1.942ArgPhe: 1.942 ± 0.985
4.993ArgGly: 4.993 ± 1.495
0.832ArgHis: 0.832 ± 0.507
3.329ArgIle: 3.329 ± 1.193
2.219ArgLys: 2.219 ± 1.263
4.716ArgLeu: 4.716 ± 1.571
1.11ArgMet: 1.11 ± 0.506
2.774ArgAsn: 2.774 ± 1.114
1.942ArgPro: 1.942 ± 1.023
0.555ArgGln: 0.555 ± 0.338
3.606ArgArg: 3.606 ± 0.682
4.438ArgSer: 4.438 ± 1.028
3.329ArgThr: 3.329 ± 0.521
3.051ArgVal: 3.051 ± 0.863
0.277ArgTrp: 0.277 ± 0.169
2.497ArgTyr: 2.497 ± 0.835
0.0ArgXaa: 0.0 ± 0.0
Ser
4.161SerAla: 4.161 ± 1.084
3.329SerCys: 3.329 ± 1.169
4.161SerAsp: 4.161 ± 0.714
3.883SerGlu: 3.883 ± 1.069
2.219SerPhe: 2.219 ± 0.712
7.212SerGly: 7.212 ± 1.978
1.942SerHis: 1.942 ± 0.817
5.548SerIle: 5.548 ± 0.987
4.438SerLys: 4.438 ± 1.273
10.541SerLeu: 10.541 ± 1.946
2.219SerMet: 2.219 ± 0.944
2.497SerAsn: 2.497 ± 0.584
3.883SerPro: 3.883 ± 1.315
2.497SerGln: 2.497 ± 1.399
4.993SerArg: 4.993 ± 1.296
11.096SerSer: 11.096 ± 2.001
5.825SerThr: 5.825 ± 0.837
4.716SerVal: 4.716 ± 0.315
1.387SerTrp: 1.387 ± 1.338
2.774SerTyr: 2.774 ± 0.731
0.0SerXaa: 0.0 ± 0.0
Thr
3.329ThrAla: 3.329 ± 1.502
0.832ThrCys: 0.832 ± 0.574
3.883ThrAsp: 3.883 ± 0.716
3.606ThrGlu: 3.606 ± 0.726
2.774ThrPhe: 2.774 ± 0.738
3.051ThrGly: 3.051 ± 1.55
1.11ThrHis: 1.11 ± 0.446
2.497ThrIle: 2.497 ± 0.58
3.883ThrLys: 3.883 ± 1.499
5.825ThrLeu: 5.825 ± 1.939
2.774ThrMet: 2.774 ± 1.172
2.774ThrAsn: 2.774 ± 0.976
4.438ThrPro: 4.438 ± 2.007
0.832ThrGln: 0.832 ± 0.93
2.774ThrArg: 2.774 ± 0.783
6.38ThrSer: 6.38 ± 0.608
3.051ThrThr: 3.051 ± 0.61
5.548ThrVal: 5.548 ± 1.026
1.664ThrTrp: 1.664 ± 0.443
2.774ThrTyr: 2.774 ± 1.187
0.0ThrXaa: 0.0 ± 0.0
Val
4.161ValAla: 4.161 ± 1.66
2.219ValCys: 2.219 ± 1.088
3.606ValAsp: 3.606 ± 1.379
3.329ValGlu: 3.329 ± 0.71
1.11ValPhe: 1.11 ± 0.865
3.329ValGly: 3.329 ± 0.75
1.11ValHis: 1.11 ± 1.045
4.716ValIle: 4.716 ± 1.099
4.716ValLys: 4.716 ± 1.91
4.438ValLeu: 4.438 ± 1.391
3.329ValMet: 3.329 ± 0.625
2.774ValAsn: 2.774 ± 0.756
4.161ValPro: 4.161 ± 0.785
2.774ValGln: 2.774 ± 1.038
3.051ValArg: 3.051 ± 1.206
5.548ValSer: 5.548 ± 1.372
3.883ValThr: 3.883 ± 1.491
4.161ValVal: 4.161 ± 0.556
1.11ValTrp: 1.11 ± 0.584
1.664ValTyr: 1.664 ± 0.701
0.0ValXaa: 0.0 ± 0.0
Trp
1.942TrpAla: 1.942 ± 0.647
0.0TrpCys: 0.0 ± 0.0
1.11TrpAsp: 1.11 ± 0.472
0.0TrpGlu: 0.0 ± 0.0
0.277TrpPhe: 0.277 ± 0.32
0.832TrpGly: 0.832 ± 0.507
0.277TrpHis: 0.277 ± 0.169
1.664TrpIle: 1.664 ± 0.612
0.277TrpLys: 0.277 ± 0.169
1.664TrpLeu: 1.664 ± 0.978
0.277TrpMet: 0.277 ± 0.377
0.832TrpAsn: 0.832 ± 0.47
0.555TrpPro: 0.555 ± 0.292
0.555TrpGln: 0.555 ± 0.655
0.832TrpArg: 0.832 ± 0.307
1.11TrpSer: 1.11 ± 0.676
1.11TrpThr: 1.11 ± 0.548
1.664TrpVal: 1.664 ± 0.612
0.555TrpTrp: 0.555 ± 0.292
0.277TrpTyr: 0.277 ± 0.169
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.0TyrAla: 0.0 ± 0.0
0.277TyrCys: 0.277 ± 0.377
2.497TyrAsp: 2.497 ± 0.562
1.11TyrGlu: 1.11 ± 0.446
2.219TyrPhe: 2.219 ± 0.748
2.774TyrGly: 2.774 ± 0.593
2.774TyrHis: 2.774 ± 0.605
3.051TyrIle: 3.051 ± 0.949
0.832TyrLys: 0.832 ± 0.354
1.942TyrLeu: 1.942 ± 0.474
0.832TyrMet: 0.832 ± 0.307
0.832TyrAsn: 0.832 ± 0.507
1.664TyrPro: 1.664 ± 1.015
1.664TyrGln: 1.664 ± 0.551
1.11TyrArg: 1.11 ± 0.676
3.329TyrSer: 3.329 ± 1.173
3.606TyrThr: 3.606 ± 0.586
2.219TyrVal: 2.219 ± 1.088
0.277TyrTrp: 0.277 ± 0.169
1.11TyrTyr: 1.11 ± 0.676
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (3606 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski