Amino acid dipepetide frequency for Hubei sobemo-like virus 18

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.941AlaAla: 2.941 ± 1.647
0.0AlaCys: 0.0 ± 0.0
6.863AlaAsp: 6.863 ± 3.554
0.98AlaGlu: 0.98 ± 0.549
1.961AlaPhe: 1.961 ± 0.381
1.961AlaGly: 1.961 ± 0.381
0.0AlaHis: 0.0 ± 0.0
6.863AlaIle: 6.863 ± 2.363
4.902AlaLys: 4.902 ± 1.265
1.961AlaLeu: 1.961 ± 0.381
5.882AlaMet: 5.882 ± 3.293
0.0AlaAsn: 0.0 ± 0.0
0.98AlaPro: 0.98 ± 0.93
0.0AlaGln: 0.0 ± 0.0
3.922AlaArg: 3.922 ± 0.763
4.902AlaSer: 4.902 ± 0.214
1.961AlaThr: 1.961 ± 1.098
1.961AlaVal: 1.961 ± 1.098
1.961AlaTrp: 1.961 ± 0.381
0.98AlaTyr: 0.98 ± 0.549
0.0AlaXaa: 0.0 ± 0.0
Cys
0.98CysAla: 0.98 ± 0.549
0.0CysCys: 0.0 ± 0.0
0.98CysAsp: 0.98 ± 0.549
0.98CysGlu: 0.98 ± 0.549
0.0CysPhe: 0.0 ± 0.0
3.922CysGly: 3.922 ± 2.195
0.0CysHis: 0.0 ± 0.0
0.98CysIle: 0.98 ± 0.93
0.0CysLys: 0.0 ± 0.0
1.961CysLeu: 1.961 ± 0.381
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.98CysGln: 0.98 ± 0.549
0.98CysArg: 0.98 ± 0.549
1.961CysSer: 1.961 ± 0.381
0.98CysThr: 0.98 ± 0.93
0.98CysVal: 0.98 ± 0.93
0.0CysTrp: 0.0 ± 0.0
0.98CysTyr: 0.98 ± 0.93
0.0CysXaa: 0.0 ± 0.0
Asp
3.922AspAla: 3.922 ± 0.763
0.0AspCys: 0.0 ± 0.0
2.941AspAsp: 2.941 ± 0.167
0.98AspGlu: 0.98 ± 0.93
3.922AspPhe: 3.922 ± 0.716
2.941AspGly: 2.941 ± 1.312
0.98AspHis: 0.98 ± 0.93
1.961AspIle: 1.961 ± 0.381
5.882AspLys: 5.882 ± 0.335
10.784AspLeu: 10.784 ± 1.358
1.961AspMet: 1.961 ± 1.098
1.961AspAsn: 1.961 ± 0.381
2.941AspPro: 2.941 ± 2.791
1.961AspGln: 1.961 ± 1.861
1.961AspArg: 1.961 ± 0.381
1.961AspSer: 1.961 ± 1.861
1.961AspThr: 1.961 ± 0.381
1.961AspVal: 1.961 ± 1.098
1.961AspTrp: 1.961 ± 1.861
5.882AspTyr: 5.882 ± 0.335
0.0AspXaa: 0.0 ± 0.0
Glu
1.961GluAla: 1.961 ± 1.098
0.0GluCys: 0.0 ± 0.0
2.941GluAsp: 2.941 ± 0.167
4.902GluGlu: 4.902 ± 1.265
1.961GluPhe: 1.961 ± 0.381
3.922GluGly: 3.922 ± 0.716
0.0GluHis: 0.0 ± 0.0
0.98GluIle: 0.98 ± 0.549
8.824GluLys: 8.824 ± 3.461
3.922GluLeu: 3.922 ± 0.763
0.98GluMet: 0.98 ± 0.598
4.902GluAsn: 4.902 ± 2.744
4.902GluPro: 4.902 ± 1.693
0.98GluGln: 0.98 ± 0.549
1.961GluArg: 1.961 ± 0.381
3.922GluSer: 3.922 ± 2.195
0.98GluThr: 0.98 ± 0.93
6.863GluVal: 6.863 ± 0.884
0.98GluTrp: 0.98 ± 0.549
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
1.961PheAla: 1.961 ± 0.381
0.0PheCys: 0.0 ± 0.0
3.922PheAsp: 3.922 ± 2.242
3.922PheGlu: 3.922 ± 0.763
1.961PhePhe: 1.961 ± 1.098
1.961PheGly: 1.961 ± 0.381
0.0PheHis: 0.0 ± 0.0
1.961PheIle: 1.961 ± 1.861
4.902PheLys: 4.902 ± 1.265
4.902PheLeu: 4.902 ± 0.214
0.98PheMet: 0.98 ± 0.93
2.941PheAsn: 2.941 ± 0.167
1.961PhePro: 1.961 ± 1.098
0.98PheGln: 0.98 ± 0.549
2.941PheArg: 2.941 ± 1.312
0.0PheSer: 0.0 ± 0.0
0.0PheThr: 0.0 ± 0.0
5.882PheVal: 5.882 ± 1.814
0.0PheTrp: 0.0 ± 0.0
0.98PheTyr: 0.98 ± 0.549
0.0PheXaa: 0.0 ± 0.0
Gly
2.941GlyAla: 2.941 ± 0.167
1.961GlyCys: 1.961 ± 1.861
2.941GlyAsp: 2.941 ± 0.167
7.843GlyGlu: 7.843 ± 1.433
5.882GlyPhe: 5.882 ± 1.144
5.882GlyGly: 5.882 ± 2.623
0.0GlyHis: 0.0 ± 0.0
0.98GlyIle: 0.98 ± 0.549
4.902GlyLys: 4.902 ± 0.214
3.922GlyLeu: 3.922 ± 0.716
2.941GlyMet: 2.941 ± 0.167
1.961GlyAsn: 1.961 ± 1.098
0.0GlyPro: 0.0 ± 0.0
2.941GlyGln: 2.941 ± 1.647
0.0GlyArg: 0.0 ± 0.0
5.882GlySer: 5.882 ± 0.335
0.98GlyThr: 0.98 ± 0.549
5.882GlyVal: 5.882 ± 0.335
2.941GlyTrp: 2.941 ± 1.312
0.98GlyTyr: 0.98 ± 0.93
0.0GlyXaa: 0.0 ± 0.0
His
3.922HisAla: 3.922 ± 0.763
0.98HisCys: 0.98 ± 0.549
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
3.922HisGly: 3.922 ± 2.242
0.0HisHis: 0.0 ± 0.0
0.98HisIle: 0.98 ± 0.93
1.961HisLys: 1.961 ± 0.381
0.98HisLeu: 0.98 ± 0.549
1.961HisMet: 1.961 ± 0.381
0.0HisAsn: 0.0 ± 0.0
1.961HisPro: 1.961 ± 1.098
0.0HisGln: 0.0 ± 0.0
2.941HisArg: 2.941 ± 1.312
0.0HisSer: 0.0 ± 0.0
0.0HisThr: 0.0 ± 0.0
2.941HisVal: 2.941 ± 1.647
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
4.902IleAla: 4.902 ± 0.214
0.98IleCys: 0.98 ± 0.549
2.941IleAsp: 2.941 ± 2.791
1.961IleGlu: 1.961 ± 0.381
0.98IlePhe: 0.98 ± 0.93
0.98IleGly: 0.98 ± 0.93
0.98IleHis: 0.98 ± 0.549
1.961IleIle: 1.961 ± 0.381
4.902IleLys: 4.902 ± 0.214
2.941IleLeu: 2.941 ± 0.167
1.961IleMet: 1.961 ± 0.381
1.961IleAsn: 1.961 ± 1.098
2.941IlePro: 2.941 ± 1.647
1.961IleGln: 1.961 ± 1.098
2.941IleArg: 2.941 ± 0.167
5.882IleSer: 5.882 ± 1.814
1.961IleThr: 1.961 ± 0.381
2.941IleVal: 2.941 ± 0.167
2.941IleTrp: 2.941 ± 1.647
0.98IleTyr: 0.98 ± 0.93
0.0IleXaa: 0.0 ± 0.0
Lys
0.98LysAla: 0.98 ± 0.549
3.922LysCys: 3.922 ± 2.195
3.922LysAsp: 3.922 ± 2.195
7.843LysGlu: 7.843 ± 2.912
0.0LysPhe: 0.0 ± 0.0
2.941LysGly: 2.941 ± 0.167
2.941LysHis: 2.941 ± 0.167
7.843LysIle: 7.843 ± 2.912
6.863LysLys: 6.863 ± 2.363
4.902LysLeu: 4.902 ± 1.693
2.941LysMet: 2.941 ± 1.312
2.941LysAsn: 2.941 ± 0.167
2.941LysPro: 2.941 ± 0.167
3.922LysGln: 3.922 ± 2.242
4.902LysArg: 4.902 ± 1.693
8.824LysSer: 8.824 ± 0.977
3.922LysThr: 3.922 ± 0.716
6.863LysVal: 6.863 ± 0.595
0.0LysTrp: 0.0 ± 0.0
2.941LysTyr: 2.941 ± 0.167
0.0LysXaa: 0.0 ± 0.0
Leu
7.843LeuAla: 7.843 ± 0.046
1.961LeuCys: 1.961 ± 1.861
5.882LeuAsp: 5.882 ± 4.102
6.863LeuGlu: 6.863 ± 2.363
5.882LeuPhe: 5.882 ± 2.623
2.941LeuGly: 2.941 ± 1.647
3.922LeuHis: 3.922 ± 2.242
2.941LeuIle: 2.941 ± 1.312
4.902LeuLys: 4.902 ± 1.693
11.765LeuLeu: 11.765 ± 2.288
0.98LeuMet: 0.98 ± 0.549
2.941LeuAsn: 2.941 ± 0.167
3.922LeuPro: 3.922 ± 0.716
1.961LeuGln: 1.961 ± 1.861
5.882LeuArg: 5.882 ± 3.293
8.824LeuSer: 8.824 ± 0.977
3.922LeuThr: 3.922 ± 2.195
8.824LeuVal: 8.824 ± 0.502
1.961LeuTrp: 1.961 ± 1.861
2.941LeuTyr: 2.941 ± 1.312
0.0LeuXaa: 0.0 ± 0.0
Met
1.961MetAla: 1.961 ± 0.381
0.0MetCys: 0.0 ± 0.0
0.98MetAsp: 0.98 ± 0.549
0.98MetGlu: 0.98 ± 0.549
0.0MetPhe: 0.0 ± 0.0
1.961MetGly: 1.961 ± 0.381
0.98MetHis: 0.98 ± 0.549
2.941MetIle: 2.941 ± 0.167
1.961MetLys: 1.961 ± 1.098
4.902MetLeu: 4.902 ± 0.214
2.941MetMet: 2.941 ± 0.167
0.98MetAsn: 0.98 ± 0.93
0.98MetPro: 0.98 ± 0.93
1.961MetGln: 1.961 ± 1.861
4.902MetArg: 4.902 ± 4.651
2.941MetSer: 2.941 ± 1.647
0.98MetThr: 0.98 ± 0.549
0.98MetVal: 0.98 ± 0.549
0.98MetTrp: 0.98 ± 0.549
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.961AsnAla: 1.961 ± 1.098
0.0AsnCys: 0.0 ± 0.0
4.902AsnAsp: 4.902 ± 0.214
1.961AsnGlu: 1.961 ± 1.098
2.941AsnPhe: 2.941 ± 0.167
3.922AsnGly: 3.922 ± 0.716
0.98AsnHis: 0.98 ± 0.549
0.98AsnIle: 0.98 ± 0.549
2.941AsnLys: 2.941 ± 0.167
6.863AsnLeu: 6.863 ± 2.363
0.0AsnMet: 0.0 ± 0.46
3.922AsnAsn: 3.922 ± 2.195
1.961AsnPro: 1.961 ± 0.381
2.941AsnGln: 2.941 ± 1.647
1.961AsnArg: 1.961 ± 1.861
2.941AsnSer: 2.941 ± 1.312
1.961AsnThr: 1.961 ± 0.381
2.941AsnVal: 2.941 ± 1.647
0.0AsnTrp: 0.0 ± 0.0
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
0.98ProAla: 0.98 ± 0.549
0.98ProCys: 0.98 ± 0.549
0.98ProAsp: 0.98 ± 0.549
3.922ProGlu: 3.922 ± 0.763
0.98ProPhe: 0.98 ± 0.549
1.961ProGly: 1.961 ± 0.381
0.98ProHis: 0.98 ± 0.93
2.941ProIle: 2.941 ± 1.312
4.902ProLys: 4.902 ± 0.214
0.98ProLeu: 0.98 ± 0.93
0.0ProMet: 0.0 ± 0.0
0.98ProAsn: 0.98 ± 0.93
0.98ProPro: 0.98 ± 0.549
2.941ProGln: 2.941 ± 1.647
0.98ProArg: 0.98 ± 0.549
2.941ProSer: 2.941 ± 1.312
3.922ProThr: 3.922 ± 2.195
2.941ProVal: 2.941 ± 0.167
0.0ProTrp: 0.0 ± 0.0
1.961ProTyr: 1.961 ± 1.861
0.0ProXaa: 0.0 ± 0.0
Gln
2.941GlnAla: 2.941 ± 2.791
0.0GlnCys: 0.0 ± 0.0
0.98GlnAsp: 0.98 ± 0.549
0.0GlnGlu: 0.0 ± 0.0
1.961GlnPhe: 1.961 ± 0.381
0.98GlnGly: 0.98 ± 0.549
0.0GlnHis: 0.0 ± 0.0
0.98GlnIle: 0.98 ± 0.549
2.941GlnLys: 2.941 ± 2.791
5.882GlnLeu: 5.882 ± 1.144
0.98GlnMet: 0.98 ± 0.93
4.902GlnAsn: 4.902 ± 0.214
0.98GlnPro: 0.98 ± 0.549
0.98GlnGln: 0.98 ± 0.93
2.941GlnArg: 2.941 ± 1.647
2.941GlnSer: 2.941 ± 1.312
0.98GlnThr: 0.98 ± 0.549
3.922GlnVal: 3.922 ± 2.195
0.0GlnTrp: 0.0 ± 0.0
0.98GlnTyr: 0.98 ± 0.549
0.0GlnXaa: 0.0 ± 0.0
Arg
0.98ArgAla: 0.98 ± 0.93
0.98ArgCys: 0.98 ± 0.549
1.961ArgAsp: 1.961 ± 0.381
2.941ArgGlu: 2.941 ± 0.167
2.941ArgPhe: 2.941 ± 0.167
3.922ArgGly: 3.922 ± 0.763
0.98ArgHis: 0.98 ± 0.93
3.922ArgIle: 3.922 ± 0.716
2.941ArgLys: 2.941 ± 1.647
3.922ArgLeu: 3.922 ± 0.716
0.98ArgMet: 0.98 ± 0.549
1.961ArgAsn: 1.961 ± 1.098
0.98ArgPro: 0.98 ± 0.549
3.922ArgGln: 3.922 ± 3.721
0.98ArgArg: 0.98 ± 0.549
4.902ArgSer: 4.902 ± 0.214
1.961ArgThr: 1.961 ± 0.381
3.922ArgVal: 3.922 ± 0.763
1.961ArgTrp: 1.961 ± 1.861
2.941ArgTyr: 2.941 ± 2.791
0.0ArgXaa: 0.0 ± 0.0
Ser
5.882SerAla: 5.882 ± 3.293
0.0SerCys: 0.0 ± 0.0
5.882SerAsp: 5.882 ± 0.335
0.98SerGlu: 0.98 ± 0.549
1.961SerPhe: 1.961 ± 1.861
6.863SerGly: 6.863 ± 0.595
1.961SerHis: 1.961 ± 1.098
5.882SerIle: 5.882 ± 1.144
7.843SerLys: 7.843 ± 0.046
8.824SerLeu: 8.824 ± 0.502
3.922SerMet: 3.922 ± 2.242
5.882SerAsn: 5.882 ± 1.144
0.98SerPro: 0.98 ± 0.549
4.902SerGln: 4.902 ± 2.744
1.961SerArg: 1.961 ± 1.098
9.804SerSer: 9.804 ± 0.428
2.941SerThr: 2.941 ± 0.167
3.922SerVal: 3.922 ± 2.242
3.922SerTrp: 3.922 ± 2.242
1.961SerTyr: 1.961 ± 0.381
0.0SerXaa: 0.0 ± 0.0
Thr
0.0ThrAla: 0.0 ± 0.0
0.98ThrCys: 0.98 ± 0.549
0.98ThrAsp: 0.98 ± 0.549
1.961ThrGlu: 1.961 ± 1.098
1.961ThrPhe: 1.961 ± 1.098
0.98ThrGly: 0.98 ± 0.549
0.98ThrHis: 0.98 ± 0.549
1.961ThrIle: 1.961 ± 0.381
3.922ThrLys: 3.922 ± 0.716
2.941ThrLeu: 2.941 ± 0.167
1.961ThrMet: 1.961 ± 1.861
0.98ThrAsn: 0.98 ± 0.549
0.98ThrPro: 0.98 ± 0.549
0.0ThrGln: 0.0 ± 0.0
0.98ThrArg: 0.98 ± 0.93
8.824ThrSer: 8.824 ± 1.982
4.902ThrThr: 4.902 ± 2.744
2.941ThrVal: 2.941 ± 0.167
0.0ThrTrp: 0.0 ± 0.0
1.961ThrTyr: 1.961 ± 1.098
0.0ThrXaa: 0.0 ± 0.0
Val
0.98ValAla: 0.98 ± 0.549
1.961ValCys: 1.961 ± 0.381
3.922ValAsp: 3.922 ± 0.763
5.882ValGlu: 5.882 ± 0.335
2.941ValPhe: 2.941 ± 1.647
8.824ValGly: 8.824 ± 1.982
3.922ValHis: 3.922 ± 2.195
2.941ValIle: 2.941 ± 1.647
4.902ValLys: 4.902 ± 1.265
4.902ValLeu: 4.902 ± 3.172
0.98ValMet: 0.98 ± 0.549
4.902ValAsn: 4.902 ± 1.265
2.941ValPro: 2.941 ± 0.167
1.961ValGln: 1.961 ± 1.861
3.922ValArg: 3.922 ± 0.716
4.902ValSer: 4.902 ± 0.214
2.941ValThr: 2.941 ± 1.647
8.824ValVal: 8.824 ± 3.461
2.941ValTrp: 2.941 ± 1.647
2.941ValTyr: 2.941 ± 0.167
0.0ValXaa: 0.0 ± 0.0
Trp
1.961TrpAla: 1.961 ± 1.098
0.0TrpCys: 0.0 ± 0.0
2.941TrpAsp: 2.941 ± 2.791
0.0TrpGlu: 0.0 ± 0.0
2.941TrpPhe: 2.941 ± 0.167
0.0TrpGly: 0.0 ± 0.0
0.98TrpHis: 0.98 ± 0.93
0.0TrpIle: 0.0 ± 0.0
0.98TrpLys: 0.98 ± 0.93
5.882TrpLeu: 5.882 ± 1.144
0.0TrpMet: 0.0 ± 0.0
0.98TrpAsn: 0.98 ± 0.549
0.98TrpPro: 0.98 ± 0.93
0.0TrpGln: 0.0 ± 0.0
0.98TrpArg: 0.98 ± 0.549
1.961TrpSer: 1.961 ± 0.381
0.98TrpThr: 0.98 ± 0.93
0.98TrpVal: 0.98 ± 0.549
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.98TyrAla: 0.98 ± 0.549
1.961TyrCys: 1.961 ± 0.381
1.961TyrAsp: 1.961 ± 0.381
0.98TyrGlu: 0.98 ± 0.93
0.98TyrPhe: 0.98 ± 0.549
0.98TyrGly: 0.98 ± 0.549
1.961TyrHis: 1.961 ± 1.861
0.0TyrIle: 0.0 ± 0.0
0.98TyrLys: 0.98 ± 0.93
3.922TyrLeu: 3.922 ± 2.242
0.98TyrMet: 0.98 ± 0.93
1.961TyrAsn: 1.961 ± 1.098
2.941TyrPro: 2.941 ± 1.312
0.98TyrGln: 0.98 ± 0.549
1.961TyrArg: 1.961 ± 1.861
1.961TyrSer: 1.961 ± 0.381
1.961TyrThr: 1.961 ± 1.098
1.961TyrVal: 1.961 ± 1.098
0.0TyrTrp: 0.0 ± 0.0
0.98TyrTyr: 0.98 ± 0.549
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1021 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski