Amino acid dipepetide frequency for Bruguierivorax albus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
12.675AlaAla: 12.675 ± 0.14
1.21AlaCys: 1.21 ± 0.034
5.783AlaAsp: 5.783 ± 0.067
5.741AlaGlu: 5.741 ± 0.07
3.657AlaPhe: 3.657 ± 0.056
9.247AlaGly: 9.247 ± 0.104
2.002AlaHis: 2.002 ± 0.041
6.029AlaIle: 6.029 ± 0.07
3.475AlaLys: 3.475 ± 0.053
12.987AlaLeu: 12.987 ± 0.104
3.165AlaMet: 3.165 ± 0.046
2.932AlaAsn: 2.932 ± 0.052
4.156AlaPro: 4.156 ± 0.062
4.292AlaGln: 4.292 ± 0.058
6.818AlaArg: 6.818 ± 0.082
5.375AlaSer: 5.375 ± 0.078
4.748AlaThr: 4.748 ± 0.068
7.459AlaVal: 7.459 ± 0.075
1.444AlaTrp: 1.444 ± 0.039
2.414AlaTyr: 2.414 ± 0.039
0.0AlaXaa: 0.0 ± 0.0
Cys
1.124CysAla: 1.124 ± 0.03
0.189CysCys: 0.189 ± 0.013
0.611CysAsp: 0.611 ± 0.022
0.562CysGlu: 0.562 ± 0.02
0.453CysPhe: 0.453 ± 0.017
1.127CysGly: 1.127 ± 0.03
0.339CysHis: 0.339 ± 0.015
0.527CysIle: 0.527 ± 0.021
0.283CysLys: 0.283 ± 0.014
1.224CysLeu: 1.224 ± 0.029
0.237CysMet: 0.237 ± 0.012
0.288CysAsn: 0.288 ± 0.013
0.543CysPro: 0.543 ± 0.024
0.459CysGln: 0.459 ± 0.018
0.925CysArg: 0.925 ± 0.025
0.596CysSer: 0.596 ± 0.02
0.421CysThr: 0.421 ± 0.016
0.729CysVal: 0.729 ± 0.02
0.179CysTrp: 0.179 ± 0.01
0.371CysTyr: 0.371 ± 0.015
0.0CysXaa: 0.0 ± 0.0
Asp
5.391AspAla: 5.391 ± 0.064
0.561AspCys: 0.561 ± 0.02
3.063AspAsp: 3.063 ± 0.044
3.289AspGlu: 3.289 ± 0.053
2.106AspPhe: 2.106 ± 0.039
4.227AspGly: 4.227 ± 0.059
1.097AspHis: 1.097 ± 0.026
3.877AspIle: 3.877 ± 0.053
2.238AspLys: 2.238 ± 0.039
4.767AspLeu: 4.767 ± 0.058
1.446AspMet: 1.446 ± 0.029
2.22AspAsn: 2.22 ± 0.038
2.527AspPro: 2.527 ± 0.037
1.747AspGln: 1.747 ± 0.038
3.199AspArg: 3.199 ± 0.05
2.796AspSer: 2.796 ± 0.045
2.587AspThr: 2.587 ± 0.041
3.66AspVal: 3.66 ± 0.052
0.89AspTrp: 0.89 ± 0.025
1.967AspTyr: 1.967 ± 0.043
0.0AspXaa: 0.0 ± 0.0
Glu
4.879GluAla: 4.879 ± 0.063
0.469GluCys: 0.469 ± 0.019
2.35GluAsp: 2.35 ± 0.039
2.729GluGlu: 2.729 ± 0.057
1.657GluPhe: 1.657 ± 0.033
3.22GluGly: 3.22 ± 0.049
1.359GluHis: 1.359 ± 0.034
3.165GluIle: 3.165 ± 0.047
2.609GluLys: 2.609 ± 0.045
5.361GluLeu: 5.361 ± 0.07
1.555GluMet: 1.555 ± 0.032
2.23GluAsn: 2.23 ± 0.039
2.044GluPro: 2.044 ± 0.036
3.092GluGln: 3.092 ± 0.055
4.002GluArg: 4.002 ± 0.064
2.629GluSer: 2.629 ± 0.043
2.827GluThr: 2.827 ± 0.047
3.021GluVal: 3.021 ± 0.046
0.673GluTrp: 0.673 ± 0.023
1.37GluTyr: 1.37 ± 0.036
0.0GluXaa: 0.0 ± 0.0
Phe
3.839PheAla: 3.839 ± 0.057
0.543PheCys: 0.543 ± 0.018
2.3PheAsp: 2.3 ± 0.041
1.577PheGlu: 1.577 ± 0.033
1.664PhePhe: 1.664 ± 0.042
3.123PheGly: 3.123 ± 0.051
0.899PheHis: 0.899 ± 0.023
2.513PheIle: 2.513 ± 0.051
1.099PheLys: 1.099 ± 0.024
3.433PheLeu: 3.433 ± 0.051
0.911PheMet: 0.911 ± 0.025
1.528PheAsn: 1.528 ± 0.029
1.647PhePro: 1.647 ± 0.036
1.145PheGln: 1.145 ± 0.028
2.046PheArg: 2.046 ± 0.032
2.861PheSer: 2.861 ± 0.045
2.174PheThr: 2.174 ± 0.036
2.382PheVal: 2.382 ± 0.042
0.55PheTrp: 0.55 ± 0.021
1.224PheTyr: 1.224 ± 0.03
0.0PheXaa: 0.0 ± 0.0
Gly
7.126GlyAla: 7.126 ± 0.078
1.04GlyCys: 1.04 ± 0.027
4.052GlyAsp: 4.052 ± 0.062
4.435GlyGlu: 4.435 ± 0.062
3.312GlyPhe: 3.312 ± 0.05
6.052GlyGly: 6.052 ± 0.086
1.843GlyHis: 1.843 ± 0.036
5.255GlyIle: 5.255 ± 0.068
3.572GlyLys: 3.572 ± 0.051
8.092GlyLeu: 8.092 ± 0.084
2.403GlyMet: 2.403 ± 0.038
2.665GlyAsn: 2.665 ± 0.047
2.481GlyPro: 2.481 ± 0.041
3.132GlyGln: 3.132 ± 0.043
5.067GlyArg: 5.067 ± 0.074
4.033GlySer: 4.033 ± 0.058
3.644GlyThr: 3.644 ± 0.058
5.744GlyVal: 5.744 ± 0.057
1.245GlyTrp: 1.245 ± 0.031
2.674GlyTyr: 2.674 ± 0.038
0.0GlyXaa: 0.0 ± 0.0
His
2.107HisAla: 2.107 ± 0.041
0.36HisCys: 0.36 ± 0.015
1.249HisAsp: 1.249 ± 0.03
1.078HisGlu: 1.078 ± 0.029
1.024HisPhe: 1.024 ± 0.025
1.841HisGly: 1.841 ± 0.034
0.726HisHis: 0.726 ± 0.024
1.497HisIle: 1.497 ± 0.03
0.694HisLys: 0.694 ± 0.024
2.378HisLeu: 2.378 ± 0.039
0.553HisMet: 0.553 ± 0.021
0.79HisAsn: 0.79 ± 0.027
1.427HisPro: 1.427 ± 0.032
1.019HisGln: 1.019 ± 0.025
1.549HisArg: 1.549 ± 0.033
1.223HisSer: 1.223 ± 0.029
1.04HisThr: 1.04 ± 0.024
1.321HisVal: 1.321 ± 0.03
0.455HisTrp: 0.455 ± 0.019
0.914HisTyr: 0.914 ± 0.027
0.0HisXaa: 0.0 ± 0.0
Ile
6.798IleAla: 6.798 ± 0.069
0.696IleCys: 0.696 ± 0.025
3.621IleAsp: 3.621 ± 0.045
3.095IleGlu: 3.095 ± 0.049
2.004IlePhe: 2.004 ± 0.052
4.887IleGly: 4.887 ± 0.064
1.261IleHis: 1.261 ± 0.03
3.586IleIle: 3.586 ± 0.057
2.246IleLys: 2.246 ± 0.043
5.393IleLeu: 5.393 ± 0.062
1.335IleMet: 1.335 ± 0.028
2.442IleAsn: 2.442 ± 0.038
2.756IlePro: 2.756 ± 0.047
1.673IleGln: 1.673 ± 0.032
3.489IleArg: 3.489 ± 0.049
3.629IleSer: 3.629 ± 0.054
3.396IleThr: 3.396 ± 0.05
3.673IleVal: 3.673 ± 0.055
0.652IleTrp: 0.652 ± 0.019
1.559IleTyr: 1.559 ± 0.032
0.0IleXaa: 0.0 ± 0.0
Lys
3.551LysAla: 3.551 ± 0.05
0.236LysCys: 0.236 ± 0.013
1.762LysAsp: 1.762 ± 0.034
1.844LysGlu: 1.844 ± 0.033
1.024LysPhe: 1.024 ± 0.026
2.456LysGly: 2.456 ± 0.039
0.782LysHis: 0.782 ± 0.024
2.342LysIle: 2.342 ± 0.04
1.879LysLys: 1.879 ± 0.048
3.549LysLeu: 3.549 ± 0.06
0.998LysMet: 0.998 ± 0.026
1.561LysAsn: 1.561 ± 0.037
1.861LysPro: 1.861 ± 0.035
1.619LysGln: 1.619 ± 0.035
2.389LysArg: 2.389 ± 0.039
2.092LysSer: 2.092 ± 0.037
2.372LysThr: 2.372 ± 0.036
2.379LysVal: 2.379 ± 0.04
0.405LysTrp: 0.405 ± 0.017
1.036LysTyr: 1.036 ± 0.022
0.0LysXaa: 0.0 ± 0.0
Leu
13.13LeuAla: 13.13 ± 0.103
1.402LeuCys: 1.402 ± 0.03
5.747LeuAsp: 5.747 ± 0.057
5.137LeuGlu: 5.137 ± 0.061
4.241LeuPhe: 4.241 ± 0.066
7.882LeuGly: 7.882 ± 0.086
2.266LeuHis: 2.266 ± 0.038
5.809LeuIle: 5.809 ± 0.072
3.906LeuLys: 3.906 ± 0.049
12.459LeuLeu: 12.459 ± 0.143
2.831LeuMet: 2.831 ± 0.047
3.859LeuAsn: 3.859 ± 0.062
6.183LeuPro: 6.183 ± 0.07
3.767LeuGln: 3.767 ± 0.053
7.094LeuArg: 7.094 ± 0.072
7.574LeuSer: 7.574 ± 0.072
6.469LeuThr: 6.469 ± 0.069
6.862LeuVal: 6.862 ± 0.076
1.376LeuTrp: 1.376 ± 0.035
2.828LeuTyr: 2.828 ± 0.042
0.0LeuXaa: 0.0 ± 0.0
Met
3.136MetAla: 3.136 ± 0.049
0.191MetCys: 0.191 ± 0.01
1.281MetAsp: 1.281 ± 0.026
1.152MetGlu: 1.152 ± 0.032
0.784MetPhe: 0.784 ± 0.025
1.822MetGly: 1.822 ± 0.038
0.494MetHis: 0.494 ± 0.018
1.416MetIle: 1.416 ± 0.033
1.141MetLys: 1.141 ± 0.025
3.053MetLeu: 3.053 ± 0.051
0.76MetMet: 0.76 ± 0.025
1.001MetAsn: 1.001 ± 0.027
1.447MetPro: 1.447 ± 0.029
1.037MetGln: 1.037 ± 0.025
1.621MetArg: 1.621 ± 0.034
1.716MetSer: 1.716 ± 0.037
1.735MetThr: 1.735 ± 0.031
1.731MetVal: 1.731 ± 0.036
0.199MetTrp: 0.199 ± 0.012
0.483MetTyr: 0.483 ± 0.017
0.0MetXaa: 0.0 ± 0.0
Asn
3.54AsnAla: 3.54 ± 0.055
0.323AsnCys: 0.323 ± 0.016
1.873AsnAsp: 1.873 ± 0.038
1.629AsnGlu: 1.629 ± 0.036
1.146AsnPhe: 1.146 ± 0.027
2.92AsnGly: 2.92 ± 0.052
0.831AsnHis: 0.831 ± 0.024
2.24AsnIle: 2.24 ± 0.039
1.261AsnLys: 1.261 ± 0.027
3.365AsnLeu: 3.365 ± 0.055
0.777AsnMet: 0.777 ± 0.024
1.408AsnAsn: 1.408 ± 0.04
2.007AsnPro: 2.007 ± 0.037
1.402AsnGln: 1.402 ± 0.036
2.206AsnArg: 2.206 ± 0.034
1.796AsnSer: 1.796 ± 0.041
1.825AsnThr: 1.825 ± 0.043
2.212AsnVal: 2.212 ± 0.039
0.489AsnTrp: 0.489 ± 0.019
1.045AsnTyr: 1.045 ± 0.028
0.0AsnXaa: 0.0 ± 0.0
Pro
5.63ProAla: 5.63 ± 0.071
0.436ProCys: 0.436 ± 0.02
3.065ProAsp: 3.065 ± 0.049
3.056ProGlu: 3.056 ± 0.047
1.838ProPhe: 1.838 ± 0.034
3.789ProGly: 3.789 ± 0.057
1.099ProHis: 1.099 ± 0.026
2.145ProIle: 2.145 ± 0.043
1.321ProLys: 1.321 ± 0.028
5.475ProLeu: 5.475 ± 0.064
1.102ProMet: 1.102 ± 0.027
1.233ProAsn: 1.233 ± 0.028
2.23ProPro: 2.23 ± 0.048
1.955ProGln: 1.955 ± 0.038
2.445ProArg: 2.445 ± 0.046
2.59ProSer: 2.59 ± 0.043
2.219ProThr: 2.219 ± 0.038
3.911ProVal: 3.911 ± 0.049
0.738ProTrp: 0.738 ± 0.024
1.383ProTyr: 1.383 ± 0.031
0.0ProXaa: 0.0 ± 0.0
Gln
4.649GlnAla: 4.649 ± 0.06
0.418GlnCys: 0.418 ± 0.018
1.865GlnAsp: 1.865 ± 0.037
1.872GlnGlu: 1.872 ± 0.037
1.367GlnPhe: 1.367 ± 0.034
3.172GlnGly: 3.172 ± 0.048
1.041GlnHis: 1.041 ± 0.023
2.118GlnIle: 2.118 ± 0.039
1.42GlnLys: 1.42 ± 0.032
4.457GlnLeu: 4.457 ± 0.066
1.043GlnMet: 1.043 ± 0.03
1.287GlnAsn: 1.287 ± 0.028
2.076GlnPro: 2.076 ± 0.034
2.528GlnGln: 2.528 ± 0.052
3.196GlnArg: 3.196 ± 0.055
2.312GlnSer: 2.312 ± 0.044
2.187GlnThr: 2.187 ± 0.046
2.765GlnVal: 2.765 ± 0.047
0.723GlnTrp: 0.723 ± 0.025
1.093GlnTyr: 1.093 ± 0.027
0.0GlnXaa: 0.0 ± 0.0
Arg
5.742ArgAla: 5.742 ± 0.065
0.71ArgCys: 0.71 ± 0.024
3.651ArgAsp: 3.651 ± 0.05
3.927ArgGlu: 3.927 ± 0.061
2.736ArgPhe: 2.736 ± 0.039
4.098ArgGly: 4.098 ± 0.05
2.134ArgHis: 2.134 ± 0.04
3.756ArgIle: 3.756 ± 0.051
2.254ArgLys: 2.254 ± 0.039
7.978ArgLeu: 7.978 ± 0.098
1.649ArgMet: 1.649 ± 0.031
2.013ArgAsn: 2.013 ± 0.041
2.983ArgPro: 2.983 ± 0.048
4.035ArgGln: 4.035 ± 0.053
5.485ArgArg: 5.485 ± 0.081
2.89ArgSer: 2.89 ± 0.048
2.697ArgThr: 2.697 ± 0.041
4.216ArgVal: 4.216 ± 0.057
1.058ArgTrp: 1.058 ± 0.031
2.352ArgTyr: 2.352 ± 0.039
0.0ArgXaa: 0.0 ± 0.0
Ser
5.989SerAla: 5.989 ± 0.074
0.583SerCys: 0.583 ± 0.02
2.859SerAsp: 2.859 ± 0.047
2.602SerGlu: 2.602 ± 0.041
2.113SerPhe: 2.113 ± 0.038
5.417SerGly: 5.417 ± 0.071
1.415SerHis: 1.415 ± 0.029
2.842SerIle: 2.842 ± 0.043
1.62SerLys: 1.62 ± 0.037
6.916SerLeu: 6.916 ± 0.079
1.405SerMet: 1.405 ± 0.03
1.578SerAsn: 1.578 ± 0.041
2.904SerPro: 2.904 ± 0.044
2.318SerGln: 2.318 ± 0.043
3.771SerArg: 3.771 ± 0.053
3.316SerSer: 3.316 ± 0.067
2.671SerThr: 2.671 ± 0.051
4.018SerVal: 4.018 ± 0.052
0.825SerTrp: 0.825 ± 0.023
1.566SerTyr: 1.566 ± 0.033
0.0SerXaa: 0.0 ± 0.0
Thr
5.477ThrAla: 5.477 ± 0.073
0.457ThrCys: 0.457 ± 0.017
2.708ThrAsp: 2.708 ± 0.044
2.453ThrGlu: 2.453 ± 0.042
1.907ThrPhe: 1.907 ± 0.036
4.591ThrGly: 4.591 ± 0.054
1.216ThrHis: 1.216 ± 0.028
2.424ThrIle: 2.424 ± 0.043
1.275ThrLys: 1.275 ± 0.032
7.306ThrLeu: 7.306 ± 0.08
1.011ThrMet: 1.011 ± 0.026
1.317ThrAsn: 1.317 ± 0.036
3.131ThrPro: 3.131 ± 0.045
1.814ThrGln: 1.814 ± 0.038
3.237ThrArg: 3.237 ± 0.05
2.631ThrSer: 2.631 ± 0.045
2.607ThrThr: 2.607 ± 0.055
3.988ThrVal: 3.988 ± 0.06
0.647ThrTrp: 0.647 ± 0.022
1.2ThrTyr: 1.2 ± 0.032
0.0ThrXaa: 0.0 ± 0.0
Val
7.251ValAla: 7.251 ± 0.078
0.767ValCys: 0.767 ± 0.024
3.621ValAsp: 3.621 ± 0.051
3.423ValGlu: 3.423 ± 0.056
2.645ValPhe: 2.645 ± 0.045
4.801ValGly: 4.801 ± 0.062
1.18ValHis: 1.18 ± 0.027
4.52ValIle: 4.52 ± 0.06
2.682ValLys: 2.682 ± 0.043
7.108ValLeu: 7.108 ± 0.087
2.087ValMet: 2.087 ± 0.039
2.605ValAsn: 2.605 ± 0.039
3.035ValPro: 3.035 ± 0.046
2.03ValGln: 2.03 ± 0.036
4.051ValArg: 4.051 ± 0.055
4.319ValSer: 4.319 ± 0.053
3.891ValThr: 3.891 ± 0.057
5.102ValVal: 5.102 ± 0.074
0.865ValTrp: 0.865 ± 0.024
1.722ValTyr: 1.722 ± 0.036
0.0ValXaa: 0.0 ± 0.0
Trp
0.971TrpAla: 0.971 ± 0.026
0.182TrpCys: 0.182 ± 0.009
0.602TrpAsp: 0.602 ± 0.021
0.521TrpGlu: 0.521 ± 0.017
0.561TrpPhe: 0.561 ± 0.019
0.895TrpGly: 0.895 ± 0.025
0.435TrpHis: 0.435 ± 0.016
0.673TrpIle: 0.673 ± 0.02
0.382TrpLys: 0.382 ± 0.018
2.221TrpLeu: 2.221 ± 0.047
0.363TrpMet: 0.363 ± 0.015
0.406TrpAsn: 0.406 ± 0.018
0.712TrpPro: 0.712 ± 0.023
0.967TrpGln: 0.967 ± 0.03
1.439TrpArg: 1.439 ± 0.035
0.745TrpSer: 0.745 ± 0.024
0.557TrpThr: 0.557 ± 0.021
0.852TrpVal: 0.852 ± 0.025
0.215TrpTrp: 0.215 ± 0.015
0.391TrpTyr: 0.391 ± 0.017
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.607TyrAla: 2.607 ± 0.042
0.412TyrCys: 0.412 ± 0.015
1.594TyrAsp: 1.594 ± 0.034
1.122TyrGlu: 1.122 ± 0.028
1.221TyrPhe: 1.221 ± 0.032
2.3TyrGly: 2.3 ± 0.044
0.826TyrHis: 0.826 ± 0.023
1.458TyrIle: 1.458 ± 0.037
0.779TyrLys: 0.779 ± 0.023
3.296TyrLeu: 3.296 ± 0.047
0.567TyrMet: 0.567 ± 0.018
0.934TyrAsn: 0.934 ± 0.024
1.51TyrPro: 1.51 ± 0.032
1.557TyrGln: 1.557 ± 0.034
2.337TyrArg: 2.337 ± 0.043
1.604TyrSer: 1.604 ± 0.034
1.328TyrThr: 1.328 ± 0.029
1.675TyrVal: 1.675 ± 0.035
0.464TyrTrp: 0.464 ± 0.017
0.974TyrTyr: 0.974 ± 0.03
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4973 proteins (1568136 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski