Amino acid dipepetide frequency for Allium cepa amalgavirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.838AlaAla: 4.838 ± 1.436
0.0AlaCys: 0.0 ± 0.0
6.22AlaAsp: 6.22 ± 2.031
6.911AlaGlu: 6.911 ± 1.682
4.147AlaPhe: 4.147 ± 0.492
5.529AlaGly: 5.529 ± 0.205
0.691AlaHis: 0.691 ± 0.349
2.764AlaIle: 2.764 ± 0.103
9.675AlaLys: 9.675 ± 4.165
5.529AlaLeu: 5.529 ± 0.205
0.691AlaMet: 0.691 ± 0.349
4.147AlaAsn: 4.147 ± 0.492
2.764AlaPro: 2.764 ± 1.19
2.764AlaGln: 2.764 ± 0.103
6.22AlaArg: 6.22 ± 0.554
6.22AlaSer: 6.22 ± 2.031
2.764AlaThr: 2.764 ± 0.103
4.147AlaVal: 4.147 ± 0.492
2.073AlaTrp: 2.073 ± 1.047
2.764AlaTyr: 2.764 ± 0.103
0.0AlaXaa: 0.0 ± 0.0
Cys
2.073CysAla: 2.073 ± 0.246
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
1.382CysGlu: 1.382 ± 0.698
0.691CysPhe: 0.691 ± 0.349
1.382CysGly: 1.382 ± 0.595
0.691CysHis: 0.691 ± 0.349
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
2.764CysLeu: 2.764 ± 0.103
0.691CysMet: 0.691 ± 0.349
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
1.382CysVal: 1.382 ± 0.698
1.382CysTrp: 1.382 ± 0.595
0.691CysTyr: 0.691 ± 0.349
0.0CysXaa: 0.0 ± 0.0
Asp
8.293AspAla: 8.293 ± 0.308
0.0AspCys: 0.0 ± 0.0
2.764AspAsp: 2.764 ± 1.395
8.293AspGlu: 8.293 ± 3.57
4.838AspPhe: 4.838 ± 0.143
2.764AspGly: 2.764 ± 1.395
0.0AspHis: 0.0 ± 0.0
3.455AspIle: 3.455 ± 1.744
1.382AspLys: 1.382 ± 0.698
5.529AspLeu: 5.529 ± 1.498
2.073AspMet: 2.073 ± 1.539
3.455AspAsn: 3.455 ± 0.452
2.764AspPro: 2.764 ± 1.19
2.073AspGln: 2.073 ± 0.246
2.764AspArg: 2.764 ± 1.19
3.455AspSer: 3.455 ± 0.452
2.073AspThr: 2.073 ± 0.246
2.764AspVal: 2.764 ± 0.103
1.382AspTrp: 1.382 ± 0.698
1.382AspTyr: 1.382 ± 0.698
0.0AspXaa: 0.0 ± 0.0
Glu
6.22GluAla: 6.22 ± 0.554
2.073GluCys: 2.073 ± 0.246
4.147GluAsp: 4.147 ± 0.8
5.529GluGlu: 5.529 ± 2.38
2.764GluPhe: 2.764 ± 0.103
2.764GluGly: 2.764 ± 0.103
0.691GluHis: 0.691 ± 0.944
2.764GluIle: 2.764 ± 1.19
3.455GluLys: 3.455 ± 0.841
8.293GluLeu: 8.293 ± 2.277
1.382GluMet: 1.382 ± 0.698
0.0GluAsn: 0.0 ± 0.0
2.764GluPro: 2.764 ± 1.19
4.838GluGln: 4.838 ± 1.149
5.529GluArg: 5.529 ± 0.205
4.147GluSer: 4.147 ± 0.8
1.382GluThr: 1.382 ± 0.595
3.455GluVal: 3.455 ± 0.841
1.382GluTrp: 1.382 ± 0.595
1.382GluTyr: 1.382 ± 0.595
0.0GluXaa: 0.0 ± 0.0
Phe
4.147PheAla: 4.147 ± 0.492
1.382PheCys: 1.382 ± 0.595
2.073PheAsp: 2.073 ± 1.047
0.691PheGlu: 0.691 ± 0.349
1.382PhePhe: 1.382 ± 0.698
0.691PheGly: 0.691 ± 0.349
0.0PheHis: 0.0 ± 0.0
3.455PheIle: 3.455 ± 1.744
2.764PheLys: 2.764 ± 0.103
2.764PheLeu: 2.764 ± 1.395
0.0PheMet: 0.0 ± 0.0
0.691PheAsn: 0.691 ± 0.349
1.382PhePro: 1.382 ± 0.698
0.691PheGln: 0.691 ± 0.349
4.147PheArg: 4.147 ± 0.8
2.073PheSer: 2.073 ± 1.047
4.147PheThr: 4.147 ± 0.492
2.764PheVal: 2.764 ± 0.103
1.382PheTrp: 1.382 ± 0.698
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
1.382GlyAla: 1.382 ± 0.595
0.0GlyCys: 0.0 ± 0.0
1.382GlyAsp: 1.382 ± 0.595
2.073GlyGlu: 2.073 ± 1.047
1.382GlyPhe: 1.382 ± 0.698
6.22GlyGly: 6.22 ± 1.847
0.0GlyHis: 0.0 ± 0.0
4.147GlyIle: 4.147 ± 2.093
3.455GlyLys: 3.455 ± 2.134
5.529GlyLeu: 5.529 ± 1.087
2.073GlyMet: 2.073 ± 1.243
2.764GlyAsn: 2.764 ± 1.395
2.764GlyPro: 2.764 ± 0.103
2.073GlyGln: 2.073 ± 0.246
2.073GlyArg: 2.073 ± 1.047
2.764GlySer: 2.764 ± 1.19
3.455GlyThr: 3.455 ± 0.452
4.838GlyVal: 4.838 ± 1.436
0.691GlyTrp: 0.691 ± 0.349
1.382GlyTyr: 1.382 ± 0.698
0.0GlyXaa: 0.0 ± 0.0
His
1.382HisAla: 1.382 ± 0.595
0.691HisCys: 0.691 ± 0.349
1.382HisAsp: 1.382 ± 0.595
1.382HisGlu: 1.382 ± 0.595
0.0HisPhe: 0.0 ± 0.0
2.073HisGly: 2.073 ± 0.246
2.073HisHis: 2.073 ± 1.047
0.0HisIle: 0.0 ± 0.0
3.455HisLys: 3.455 ± 0.841
2.073HisLeu: 2.073 ± 0.246
0.0HisMet: 0.0 ± 0.0
0.691HisAsn: 0.691 ± 0.349
0.691HisPro: 0.691 ± 0.349
0.691HisGln: 0.691 ± 0.349
4.838HisArg: 4.838 ± 1.149
0.0HisSer: 0.0 ± 0.0
0.0HisThr: 0.0 ± 0.0
1.382HisVal: 1.382 ± 0.698
0.691HisTrp: 0.691 ± 0.349
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
1.382IleAla: 1.382 ± 0.595
0.691IleCys: 0.691 ± 0.349
8.984IleAsp: 8.984 ± 1.95
2.764IleGlu: 2.764 ± 1.395
1.382IlePhe: 1.382 ± 0.595
2.764IleGly: 2.764 ± 1.395
2.073IleHis: 2.073 ± 1.047
3.455IleIle: 3.455 ± 1.744
5.529IleLys: 5.529 ± 0.205
2.764IleLeu: 2.764 ± 0.103
0.691IleMet: 0.691 ± 0.349
1.382IleAsn: 1.382 ± 0.595
2.764IlePro: 2.764 ± 0.103
3.455IleGln: 3.455 ± 0.841
5.529IleArg: 5.529 ± 0.205
4.147IleSer: 4.147 ± 0.8
1.382IleThr: 1.382 ± 0.595
2.073IleVal: 2.073 ± 1.047
0.691IleTrp: 0.691 ± 0.349
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
7.602LysAla: 7.602 ± 1.333
2.073LysCys: 2.073 ± 0.246
4.838LysAsp: 4.838 ± 0.143
4.147LysGlu: 4.147 ± 0.492
2.764LysPhe: 2.764 ± 1.395
2.073LysGly: 2.073 ± 1.539
0.691LysHis: 0.691 ± 0.349
5.529LysIle: 5.529 ± 1.087
4.838LysLys: 4.838 ± 2.729
5.529LysLeu: 5.529 ± 1.087
1.382LysMet: 1.382 ± 0.273
0.0LysAsn: 0.0 ± 0.0
6.22LysPro: 6.22 ± 0.554
2.764LysGln: 2.764 ± 2.483
6.911LysArg: 6.911 ± 1.682
4.147LysSer: 4.147 ± 1.785
4.147LysThr: 4.147 ± 1.785
8.984LysVal: 8.984 ± 1.928
0.0LysTrp: 0.0 ± 0.0
2.764LysTyr: 2.764 ± 0.103
0.0LysXaa: 0.0 ± 0.0
Leu
4.838LeuAla: 4.838 ± 2.729
0.691LeuCys: 0.691 ± 0.349
3.455LeuAsp: 3.455 ± 0.452
6.911LeuGlu: 6.911 ± 0.39
2.764LeuPhe: 2.764 ± 1.395
2.764LeuGly: 2.764 ± 0.103
3.455LeuHis: 3.455 ± 0.452
3.455LeuIle: 3.455 ± 0.841
7.602LeuLys: 7.602 ± 1.333
8.293LeuLeu: 8.293 ± 1.601
1.382LeuMet: 1.382 ± 0.595
5.529LeuAsn: 5.529 ± 0.205
4.838LeuPro: 4.838 ± 1.149
8.293LeuGln: 8.293 ± 0.984
6.22LeuArg: 6.22 ± 0.554
10.366LeuSer: 10.366 ± 0.062
4.838LeuThr: 4.838 ± 1.149
5.529LeuVal: 5.529 ± 0.205
1.382LeuTrp: 1.382 ± 0.698
3.455LeuTyr: 3.455 ± 0.452
0.0LeuXaa: 0.0 ± 0.0
Met
0.691MetAla: 0.691 ± 0.349
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
0.691MetGlu: 0.691 ± 0.944
1.382MetPhe: 1.382 ± 0.698
0.0MetGly: 0.0 ± 0.0
2.073MetHis: 2.073 ± 0.246
1.382MetIle: 1.382 ± 0.698
0.691MetLys: 0.691 ± 0.349
2.764MetLeu: 2.764 ± 1.395
0.691MetMet: 0.691 ± 0.349
0.691MetAsn: 0.691 ± 0.349
2.073MetPro: 2.073 ± 0.246
0.0MetGln: 0.0 ± 0.0
1.382MetArg: 1.382 ± 0.698
1.382MetSer: 1.382 ± 0.595
1.382MetThr: 1.382 ± 0.595
2.073MetVal: 2.073 ± 1.047
0.0MetTrp: 0.0 ± 0.0
2.073MetTyr: 2.073 ± 0.246
0.0MetXaa: 0.0 ± 0.0
Asn
5.529AsnAla: 5.529 ± 0.205
0.691AsnCys: 0.691 ± 0.349
0.691AsnAsp: 0.691 ± 0.349
1.382AsnGlu: 1.382 ± 0.698
1.382AsnPhe: 1.382 ± 0.698
0.0AsnGly: 0.0 ± 0.0
2.764AsnHis: 2.764 ± 0.103
3.455AsnIle: 3.455 ± 0.841
2.764AsnLys: 2.764 ± 0.103
2.073AsnLeu: 2.073 ± 0.246
1.382AsnMet: 1.382 ± 0.698
2.073AsnAsn: 2.073 ± 1.047
3.455AsnPro: 3.455 ± 1.744
2.073AsnGln: 2.073 ± 0.246
0.0AsnArg: 0.0 ± 0.0
0.691AsnSer: 0.691 ± 0.944
2.073AsnThr: 2.073 ± 0.246
4.147AsnVal: 4.147 ± 0.8
0.691AsnTrp: 0.691 ± 0.349
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
3.455ProAla: 3.455 ± 2.134
0.691ProCys: 0.691 ± 0.349
3.455ProAsp: 3.455 ± 0.841
3.455ProGlu: 3.455 ± 0.452
1.382ProPhe: 1.382 ± 0.698
1.382ProGly: 1.382 ± 0.698
0.691ProHis: 0.691 ± 0.944
3.455ProIle: 3.455 ± 1.744
2.764ProLys: 2.764 ± 0.103
6.911ProLeu: 6.911 ± 0.903
0.691ProMet: 0.691 ± 0.349
0.0ProAsn: 0.0 ± 0.0
4.147ProPro: 4.147 ± 0.8
2.764ProGln: 2.764 ± 0.103
2.073ProArg: 2.073 ± 0.246
4.838ProSer: 4.838 ± 1.436
4.147ProThr: 4.147 ± 0.8
2.764ProVal: 2.764 ± 0.103
0.0ProTrp: 0.0 ± 0.0
2.764ProTyr: 2.764 ± 1.395
0.0ProXaa: 0.0 ± 0.0
Gln
6.22GlnAla: 6.22 ± 0.738
0.0GlnCys: 0.0 ± 0.0
2.764GlnAsp: 2.764 ± 1.19
1.382GlnGlu: 1.382 ± 0.595
0.691GlnPhe: 0.691 ± 0.349
1.382GlnGly: 1.382 ± 0.698
2.764GlnHis: 2.764 ± 1.19
3.455GlnIle: 3.455 ± 0.841
4.147GlnLys: 4.147 ± 1.785
6.911GlnLeu: 6.911 ± 0.39
0.691GlnMet: 0.691 ± 0.349
1.382GlnAsn: 1.382 ± 0.595
0.691GlnPro: 0.691 ± 0.349
2.764GlnGln: 2.764 ± 1.19
4.147GlnArg: 4.147 ± 1.785
2.764GlnSer: 2.764 ± 0.103
0.0GlnThr: 0.0 ± 0.0
2.073GlnVal: 2.073 ± 1.047
0.0GlnTrp: 0.0 ± 0.0
2.764GlnTyr: 2.764 ± 0.103
0.0GlnXaa: 0.0 ± 0.0
Arg
4.838ArgAla: 4.838 ± 0.143
2.073ArgCys: 2.073 ± 1.047
2.764ArgAsp: 2.764 ± 1.19
5.529ArgGlu: 5.529 ± 1.087
3.455ArgPhe: 3.455 ± 0.452
5.529ArgGly: 5.529 ± 1.498
0.691ArgHis: 0.691 ± 0.349
2.764ArgIle: 2.764 ± 0.103
8.984ArgLys: 8.984 ± 3.221
4.147ArgLeu: 4.147 ± 0.8
1.382ArgMet: 1.382 ± 0.595
3.455ArgAsn: 3.455 ± 1.744
4.147ArgPro: 4.147 ± 2.093
1.382ArgGln: 1.382 ± 0.698
4.147ArgArg: 4.147 ± 1.785
2.764ArgSer: 2.764 ± 0.103
2.764ArgThr: 2.764 ± 0.103
5.529ArgVal: 5.529 ± 1.087
2.073ArgTrp: 2.073 ± 0.246
1.382ArgTyr: 1.382 ± 0.698
0.0ArgXaa: 0.0 ± 0.0
Ser
8.293SerAla: 8.293 ± 3.57
0.691SerCys: 0.691 ± 0.349
4.147SerAsp: 4.147 ± 0.8
0.691SerGlu: 0.691 ± 0.349
1.382SerPhe: 1.382 ± 0.595
5.529SerGly: 5.529 ± 2.38
2.764SerHis: 2.764 ± 0.103
2.764SerIle: 2.764 ± 1.395
6.911SerLys: 6.911 ± 2.975
4.147SerLeu: 4.147 ± 0.8
1.382SerMet: 1.382 ± 0.698
3.455SerAsn: 3.455 ± 0.841
1.382SerPro: 1.382 ± 0.595
2.073SerGln: 2.073 ± 0.246
4.147SerArg: 4.147 ± 2.093
6.22SerSer: 6.22 ± 3.324
2.073SerThr: 2.073 ± 1.047
3.455SerVal: 3.455 ± 0.452
1.382SerTrp: 1.382 ± 0.698
0.0SerTyr: 0.0 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
4.838ThrAla: 4.838 ± 1.149
0.0ThrCys: 0.0 ± 0.0
4.147ThrAsp: 4.147 ± 0.8
4.838ThrGlu: 4.838 ± 0.143
0.691ThrPhe: 0.691 ± 0.349
2.764ThrGly: 2.764 ± 0.103
0.691ThrHis: 0.691 ± 0.349
1.382ThrIle: 1.382 ± 0.595
3.455ThrLys: 3.455 ± 0.452
3.455ThrLeu: 3.455 ± 0.452
1.382ThrMet: 1.382 ± 0.595
0.691ThrAsn: 0.691 ± 0.349
2.073ThrPro: 2.073 ± 0.246
2.073ThrGln: 2.073 ± 1.539
3.455ThrArg: 3.455 ± 0.841
2.073ThrSer: 2.073 ± 0.246
2.764ThrThr: 2.764 ± 1.395
1.382ThrVal: 1.382 ± 0.595
0.691ThrTrp: 0.691 ± 0.349
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
2.073ValAla: 2.073 ± 1.047
1.382ValCys: 1.382 ± 0.595
6.22ValAsp: 6.22 ± 0.554
4.838ValGlu: 4.838 ± 1.436
2.073ValPhe: 2.073 ± 1.047
4.147ValGly: 4.147 ± 0.492
0.0ValHis: 0.0 ± 0.0
2.764ValIle: 2.764 ± 1.395
3.455ValLys: 3.455 ± 0.452
8.984ValLeu: 8.984 ± 1.928
2.764ValMet: 2.764 ± 1.395
2.073ValAsn: 2.073 ± 1.047
6.22ValPro: 6.22 ± 0.738
4.147ValGln: 4.147 ± 1.785
3.455ValArg: 3.455 ± 0.841
4.147ValSer: 4.147 ± 2.093
1.382ValThr: 1.382 ± 0.698
0.691ValVal: 0.691 ± 0.349
3.455ValTrp: 3.455 ± 0.841
0.691ValTyr: 0.691 ± 0.349
0.0ValXaa: 0.0 ± 0.0
Trp
2.073TrpAla: 2.073 ± 0.246
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
1.382TrpGlu: 1.382 ± 0.698
1.382TrpPhe: 1.382 ± 0.698
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
1.382TrpIle: 1.382 ± 0.698
2.073TrpLys: 2.073 ± 1.047
2.764TrpLeu: 2.764 ± 0.103
0.0TrpMet: 0.0 ± 0.0
2.764TrpAsn: 2.764 ± 1.19
0.0TrpPro: 0.0 ± 0.0
0.691TrpGln: 0.691 ± 0.349
1.382TrpArg: 1.382 ± 0.698
0.691TrpSer: 0.691 ± 0.349
2.073TrpThr: 2.073 ± 0.246
1.382TrpVal: 1.382 ± 0.698
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.691TyrAla: 0.691 ± 0.349
0.0TyrCys: 0.0 ± 0.0
2.073TyrAsp: 2.073 ± 0.246
0.691TyrGlu: 0.691 ± 0.349
0.691TyrPhe: 0.691 ± 0.349
1.382TyrGly: 1.382 ± 0.698
0.691TyrHis: 0.691 ± 0.349
2.073TyrIle: 2.073 ± 0.246
0.0TyrLys: 0.0 ± 0.0
4.838TyrLeu: 4.838 ± 0.143
0.0TyrMet: 0.0 ± 0.0
2.073TyrAsn: 2.073 ± 1.047
0.691TyrPro: 0.691 ± 0.349
1.382TyrGln: 1.382 ± 0.595
1.382TyrArg: 1.382 ± 0.698
0.0TyrSer: 0.0 ± 0.0
0.0TyrThr: 0.0 ± 0.0
4.147TyrVal: 4.147 ± 0.8
0.691TyrTrp: 0.691 ± 0.349
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1448 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski