Schistosoma margrebowiei

Taxonomy: cellular organisms; Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Protostomia; Spiralia; Lophotrochozoa; Platyhelminthes; Trematoda; Digenea; Strigeidida; Schistosomatoidea; Schistosomatidae; Schistosoma

Average proteome isoelectric point is 7.03

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 25527 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A183LRR1|A0A183LRR1_9TREM Uncharacterized protein OS=Schistosoma margrebowiei OX=48269 GN=SMRZ_LOCUS6486 PE=4 SV=1
FF1 pKa = 7.13SAGISEE7 pKa = 4.57IPVSTTANTSHH18 pKa = 7.43LDD20 pKa = 3.61YY21 pKa = 11.31SQLDD25 pKa = 3.91LNDD28 pKa = 4.35DD29 pKa = 4.25LVAKK33 pKa = 10.14DD34 pKa = 4.18LQLTDD39 pKa = 4.6SDD41 pKa = 5.57DD42 pKa = 4.62DD43 pKa = 5.6DD44 pKa = 6.39GDD46 pKa = 4.07SSLTGQGGEE55 pKa = 4.23LCTDD59 pKa = 3.51EE60 pKa = 5.55NDD62 pKa = 3.72ATVMSYY68 pKa = 11.05NIDD71 pKa = 3.53QDD73 pKa = 4.18NDD75 pKa = 3.72DD76 pKa = 5.89DD77 pKa = 5.46DD78 pKa = 6.14DD79 pKa = 4.23QMHH82 pKa = 7.24RR83 pKa = 11.84NTILQYY89 pKa = 10.09TEE91 pKa = 3.69YY92 pKa = 9.75HH93 pKa = 5.65QNEE96 pKa = 4.66SEE98 pKa = 4.41MISHH102 pKa = 7.23NDD104 pKa = 3.37NSFTTYY110 pKa = 10.25NVQHH114 pKa = 6.56RR115 pKa = 11.84QRR117 pKa = 11.84LDD119 pKa = 3.34HH120 pKa = 7.74DD121 pKa = 4.62DD122 pKa = 3.85SNNNNNHH129 pKa = 5.79NNSHH133 pKa = 5.85PTFFISDD140 pKa = 4.42DD141 pKa = 4.31DD142 pKa = 6.05DD143 pKa = 6.0DD144 pKa = 6.07DD145 pKa = 3.9NN146 pKa = 5.8

Molecular weight: 16.54 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A3P8CR17|A0A3P8CR17_9TREM Uncharacterized protein OS=Schistosoma margrebowiei OX=48269 GN=SMRZ_LOCUS9523 PE=4 SV=1
MM1 pKa = 7.73LILLRR6 pKa = 11.84LILLLLLQRR15 pKa = 11.84LLRR18 pKa = 11.84LPRR21 pKa = 11.84LLLLQRR27 pKa = 11.84LLRR30 pKa = 11.84LLPRR34 pKa = 11.84LILLVLLLLLLLLLLLRR51 pKa = 11.84LPLLRR56 pKa = 11.84LLLLLLRR63 pKa = 11.84LLLLLLLLLLLIRR76 pKa = 11.84LLLLLYY82 pKa = 10.7LLLRR86 pKa = 11.84RR87 pKa = 11.84RR88 pKa = 11.84LLLLRR93 pKa = 11.84LLRR96 pKa = 11.84LLLLLLLLLLLRR108 pKa = 11.84LLLLRR113 pKa = 11.84ILLILLLLLLLLLLLLLLLRR133 pKa = 11.84LLLLLRR139 pKa = 11.84LLRR142 pKa = 11.84LLLLLLLRR150 pKa = 11.84LLLLLQLLLLLRR162 pKa = 11.84LLLRR166 pKa = 11.84LLLLLLLLLLILLLLLLLLLLIIIIILLLLLLLLLILLLLRR207 pKa = 11.84LIRR210 pKa = 11.84LQLLLLLLLILYY222 pKa = 9.87YY223 pKa = 10.46YY224 pKa = 10.52DD225 pKa = 3.32YY226 pKa = 11.11YY227 pKa = 11.68YY228 pKa = 10.49PLLLLQLLLLLLLPLLRR245 pKa = 11.84LLLLPRR251 pKa = 11.84LLRR254 pKa = 11.84LQRR257 pKa = 11.84LQLLLLRR264 pKa = 11.84LLLLLLLLLLLPLRR278 pKa = 11.84LRR280 pKa = 11.84LLLLLLLLLLLILLLLLLLLLLLLLLILLLLRR312 pKa = 11.84LLLLLVLLLLLLLLLRR328 pKa = 11.84LLLLRR333 pKa = 11.84LLLRR337 pKa = 11.84VLLLLLLLLRR347 pKa = 11.84LLLLLLLLLLLLLLLIIIIILLLLLLLLILLLLRR381 pKa = 11.84LIRR384 pKa = 11.84LQPLLLLLLLLLLLLLLLLLLRR406 pKa = 11.84LLLLRR411 pKa = 11.84LLLRR415 pKa = 11.84LLLLLRR421 pKa = 11.84LLRR424 pKa = 11.84ILLLLLLLLLLLLLLLILQRR444 pKa = 11.84VVPLRR449 pKa = 11.84LLLLLLLLIIIILIIIIIILLLLLLPLSRR478 pKa = 11.84LLRR481 pKa = 11.84LQRR484 pKa = 11.84LILLLRR490 pKa = 11.84LLLLLLLLLLLLQRR504 pKa = 11.84LLRR507 pKa = 11.84LLLLQRR513 pKa = 11.84ILRR516 pKa = 11.84LQRR519 pKa = 11.84LLLILLLLLPLLRR532 pKa = 11.84LLLLLLLLLLLIRR545 pKa = 11.84LLLLRR550 pKa = 11.84LLLLLRR556 pKa = 11.84LLRR559 pKa = 11.84LLLLLRR565 pKa = 11.84LLLLLLLLLLLLLRR579 pKa = 11.84LLQRR583 pKa = 11.84LLRR586 pKa = 11.84LLLILLLLLLLRR598 pKa = 11.84QLLILLLLLILLLLLLLLLLLLLRR622 pKa = 11.84LLLLRR627 pKa = 11.84LLLRR631 pKa = 11.84LLRR634 pKa = 11.84ILLLLLLLLLLLLLRR649 pKa = 11.84LLLLLLLLIIIIIIILLPLLLLLLLLLLLILQRR682 pKa = 11.84LVPLRR687 pKa = 11.84LLLLLLLIIIIIIIIIIIKK706 pKa = 10.11IIIKK710 pKa = 10.25IILLLLLLLLLLLLLRR726 pKa = 11.84LILLLRR732 pKa = 11.84LLPLLLLLLLLLLLLLLRR750 pKa = 11.84ILPLPRR756 pKa = 11.84LLRR759 pKa = 11.84LQCLIILLRR768 pKa = 11.84LLLLLLLLLLLLQRR782 pKa = 11.84LPRR785 pKa = 11.84LLLLQRR791 pKa = 11.84ILRR794 pKa = 11.84LQRR797 pKa = 11.84LLLLLLLLLPLLRR810 pKa = 11.84LLLLLLLLLIIIIILLPLQHH830 pKa = 7.1LLLLLLLLLLLILLLLLLLLLLLILLLLLLLLLLLLLLLRR870 pKa = 11.84LLLLLLLLLLLLLLLLLLLLPLLRR894 pKa = 11.84LLLLLLLLLLRR905 pKa = 11.84LLQRR909 pKa = 11.84LLRR912 pKa = 11.84LLVLLLLLILILLLLLLLLLLRR934 pKa = 11.84LLLLLRR940 pKa = 11.84LLPLLLLLLLLLLLLRR956 pKa = 11.84LLPLPRR962 pKa = 11.84LLRR965 pKa = 11.84LQQ967 pKa = 3.56

Molecular weight: 113.8 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

25527

0

25527

6596622

29

5872

258.4

29.29

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

4.618 ± 0.018

2.033 ± 0.011

5.219 ± 0.014

5.551 ± 0.019

3.714 ± 0.013

4.522 ± 0.021

2.901 ± 0.01

6.739 ± 0.019

6.001 ± 0.019

9.515 ± 0.023

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.165 ± 0.007

7.219 ± 0.03

4.269 ± 0.017

4.386 ± 0.013

5.15 ± 0.017

9.651 ± 0.031

6.768 ± 0.027

5.318 ± 0.015

1.153 ± 0.007

3.103 ± 0.01
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski