Amino acid dipepetide frequency for Avian metaavulavirus 6

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.067AlaAla: 7.067 ± 0.966
1.039AlaCys: 1.039 ± 0.424
3.326AlaAsp: 3.326 ± 0.702
3.326AlaGlu: 3.326 ± 1.417
1.039AlaPhe: 1.039 ± 0.495
4.157AlaGly: 4.157 ± 0.466
0.624AlaHis: 0.624 ± 0.332
5.612AlaIle: 5.612 ± 0.712
4.365AlaLys: 4.365 ± 1.479
8.106AlaLeu: 8.106 ± 1.548
2.494AlaMet: 2.494 ± 0.834
2.286AlaAsn: 2.286 ± 0.455
3.534AlaPro: 3.534 ± 1.797
3.534AlaGln: 3.534 ± 0.606
3.741AlaArg: 3.741 ± 0.984
5.612AlaSer: 5.612 ± 1.009
6.859AlaThr: 6.859 ± 1.261
5.196AlaVal: 5.196 ± 1.129
0.624AlaTrp: 0.624 ± 0.218
2.494AlaTyr: 2.494 ± 0.539
0.0AlaXaa: 0.0 ± 0.0
Cys
1.455CysAla: 1.455 ± 0.555
0.624CysCys: 0.624 ± 0.335
1.247CysAsp: 1.247 ± 0.408
1.455CysGlu: 1.455 ± 0.384
0.831CysPhe: 0.831 ± 0.208
0.416CysGly: 0.416 ± 0.32
1.247CysHis: 1.247 ± 0.408
0.831CysIle: 0.831 ± 0.334
0.831CysLys: 0.831 ± 0.372
2.079CysLeu: 2.079 ± 0.585
0.208CysMet: 0.208 ± 0.243
0.624CysAsn: 0.624 ± 0.535
0.831CysPro: 0.831 ± 0.294
0.624CysGln: 0.624 ± 0.22
0.831CysArg: 0.831 ± 0.3
2.286CysSer: 2.286 ± 0.641
1.455CysThr: 1.455 ± 0.358
2.079CysVal: 2.079 ± 0.418
0.0CysTrp: 0.0 ± 0.0
0.624CysTyr: 0.624 ± 0.535
0.0CysXaa: 0.0 ± 0.0
Asp
2.702AspAla: 2.702 ± 0.89
0.416AspCys: 0.416 ± 0.175
2.079AspAsp: 2.079 ± 0.636
1.039AspGlu: 1.039 ± 0.275
1.871AspPhe: 1.871 ± 0.583
3.118AspGly: 3.118 ± 0.494
1.247AspHis: 1.247 ± 0.445
3.949AspIle: 3.949 ± 0.781
2.702AspLys: 2.702 ± 0.614
4.781AspLeu: 4.781 ± 0.634
2.079AspMet: 2.079 ± 0.421
2.91AspAsn: 2.91 ± 0.64
4.157AspPro: 4.157 ± 0.777
1.455AspGln: 1.455 ± 0.408
2.702AspArg: 2.702 ± 0.771
2.702AspSer: 2.702 ± 0.728
4.157AspThr: 4.157 ± 0.531
1.455AspVal: 1.455 ± 0.574
0.416AspTrp: 0.416 ± 0.175
1.455AspTyr: 1.455 ± 0.362
0.0AspXaa: 0.0 ± 0.0
Glu
3.326GluAla: 3.326 ± 1.404
0.624GluCys: 0.624 ± 0.239
3.949GluAsp: 3.949 ± 1.266
3.118GluGlu: 3.118 ± 0.567
1.663GluPhe: 1.663 ± 0.893
3.118GluGly: 3.118 ± 0.291
1.455GluHis: 1.455 ± 0.411
3.118GluIle: 3.118 ± 0.771
1.247GluLys: 1.247 ± 0.28
6.651GluLeu: 6.651 ± 1.001
1.455GluMet: 1.455 ± 0.288
2.91GluAsn: 2.91 ± 0.381
1.663GluPro: 1.663 ± 0.437
1.455GluGln: 1.455 ± 0.555
2.494GluArg: 2.494 ± 0.498
6.028GluSer: 6.028 ± 1.006
3.326GluThr: 3.326 ± 1.082
3.741GluVal: 3.741 ± 0.669
0.208GluTrp: 0.208 ± 0.112
2.286GluTyr: 2.286 ± 0.427
0.0GluXaa: 0.0 ± 0.0
Phe
1.455PheAla: 1.455 ± 0.526
1.039PheCys: 1.039 ± 0.285
2.286PheAsp: 2.286 ± 0.864
2.079PheGlu: 2.079 ± 1.117
1.871PhePhe: 1.871 ± 0.473
1.247PheGly: 1.247 ± 0.439
0.831PheHis: 0.831 ± 0.312
2.079PheIle: 2.079 ± 0.598
1.871PheLys: 1.871 ± 0.473
4.157PheLeu: 4.157 ± 1.186
0.624PheMet: 0.624 ± 0.401
1.455PheAsn: 1.455 ± 0.661
0.624PhePro: 0.624 ± 0.451
0.624PheGln: 0.624 ± 0.227
1.247PheArg: 1.247 ± 0.408
2.702PheSer: 2.702 ± 0.772
2.286PheThr: 2.286 ± 0.474
2.494PheVal: 2.494 ± 0.727
0.0PheTrp: 0.0 ± 0.0
0.624PheTyr: 0.624 ± 0.219
0.0PheXaa: 0.0 ± 0.0
Gly
4.157GlyAla: 4.157 ± 0.928
1.871GlyCys: 1.871 ± 0.689
4.365GlyAsp: 4.365 ± 0.424
3.326GlyGlu: 3.326 ± 0.7
2.286GlyPhe: 2.286 ± 1.06
3.118GlyGly: 3.118 ± 0.793
2.079GlyHis: 2.079 ± 0.699
5.196GlyIle: 5.196 ± 0.615
3.949GlyLys: 3.949 ± 0.893
5.82GlyLeu: 5.82 ± 1.049
1.247GlyMet: 1.247 ± 0.284
2.702GlyAsn: 2.702 ± 0.847
1.871GlyPro: 1.871 ± 0.534
1.871GlyGln: 1.871 ± 0.631
3.741GlyArg: 3.741 ± 0.534
4.365GlySer: 4.365 ± 0.905
2.702GlyThr: 2.702 ± 0.69
3.741GlyVal: 3.741 ± 0.914
0.0GlyTrp: 0.0 ± 0.0
2.286GlyTyr: 2.286 ± 0.577
0.0GlyXaa: 0.0 ± 0.0
His
1.663HisAla: 1.663 ± 0.705
0.208HisCys: 0.208 ± 0.112
0.624HisAsp: 0.624 ± 0.249
0.416HisGlu: 0.416 ± 0.223
0.416HisPhe: 0.416 ± 0.279
0.831HisGly: 0.831 ± 0.435
0.831HisHis: 0.831 ± 0.447
1.455HisIle: 1.455 ± 0.782
0.208HisLys: 0.208 ± 0.112
3.949HisLeu: 3.949 ± 0.99
0.208HisMet: 0.208 ± 0.169
1.039HisAsn: 1.039 ± 0.39
2.494HisPro: 2.494 ± 0.574
1.039HisGln: 1.039 ± 0.268
2.079HisArg: 2.079 ± 0.348
1.663HisSer: 1.663 ± 0.44
1.247HisThr: 1.247 ± 0.387
1.247HisVal: 1.247 ± 0.492
0.624HisTrp: 0.624 ± 0.343
0.208HisTyr: 0.208 ± 0.112
0.0HisXaa: 0.0 ± 0.0
Ile
5.196IleAla: 5.196 ± 0.687
0.624IleCys: 0.624 ± 0.211
3.118IleAsp: 3.118 ± 0.653
4.157IleGlu: 4.157 ± 0.447
2.702IlePhe: 2.702 ± 0.754
3.118IleGly: 3.118 ± 0.733
2.286IleHis: 2.286 ± 1.057
4.157IleIle: 4.157 ± 0.838
4.365IleLys: 4.365 ± 0.933
5.196IleLeu: 5.196 ± 0.944
2.079IleMet: 2.079 ± 0.418
2.702IleAsn: 2.702 ± 0.609
2.286IlePro: 2.286 ± 0.567
2.91IleGln: 2.91 ± 0.53
4.157IleArg: 4.157 ± 1.096
6.859IleSer: 6.859 ± 1.405
5.404IleThr: 5.404 ± 1.136
4.989IleVal: 4.989 ± 0.835
1.247IleTrp: 1.247 ± 0.262
0.416IleTyr: 0.416 ± 0.372
0.0IleXaa: 0.0 ± 0.0
Lys
2.286LysAla: 2.286 ± 0.546
1.039LysCys: 1.039 ± 0.498
1.663LysAsp: 1.663 ± 0.313
2.702LysGlu: 2.702 ± 0.499
1.871LysPhe: 1.871 ± 0.463
3.741LysGly: 3.741 ± 1.221
1.247LysHis: 1.247 ± 0.441
1.663LysIle: 1.663 ± 0.388
2.702LysLys: 2.702 ± 0.758
4.781LysLeu: 4.781 ± 1.176
1.871LysMet: 1.871 ± 0.708
1.247LysAsn: 1.247 ± 0.438
1.871LysPro: 1.871 ± 0.479
1.455LysGln: 1.455 ± 0.456
2.079LysArg: 2.079 ± 0.572
3.534LysSer: 3.534 ± 0.398
2.702LysThr: 2.702 ± 0.805
3.949LysVal: 3.949 ± 0.706
0.208LysTrp: 0.208 ± 0.26
2.079LysTyr: 2.079 ± 0.482
0.0LysXaa: 0.0 ± 0.0
Leu
8.73LeuAla: 8.73 ± 1.266
2.702LeuCys: 2.702 ± 0.72
4.365LeuAsp: 4.365 ± 0.591
6.859LeuGlu: 6.859 ± 1.619
3.326LeuPhe: 3.326 ± 0.911
5.404LeuGly: 5.404 ± 0.681
2.494LeuHis: 2.494 ± 0.538
5.82LeuIle: 5.82 ± 0.801
4.573LeuLys: 4.573 ± 0.868
10.601LeuLeu: 10.601 ± 1.712
2.079LeuMet: 2.079 ± 0.549
5.404LeuAsn: 5.404 ± 0.803
2.91LeuPro: 2.91 ± 0.597
4.781LeuGln: 4.781 ± 0.567
4.781LeuArg: 4.781 ± 1.131
7.483LeuSer: 7.483 ± 1.253
7.691LeuThr: 7.691 ± 1.12
6.859LeuVal: 6.859 ± 1.064
2.494LeuTrp: 2.494 ± 0.803
3.534LeuTyr: 3.534 ± 0.76
0.0LeuXaa: 0.0 ± 0.0
Met
2.702MetAla: 2.702 ± 0.417
0.208MetCys: 0.208 ± 0.112
0.624MetAsp: 0.624 ± 0.218
0.416MetGlu: 0.416 ± 0.175
0.624MetPhe: 0.624 ± 0.26
2.494MetGly: 2.494 ± 0.681
0.416MetHis: 0.416 ± 0.234
1.663MetIle: 1.663 ± 0.454
1.039MetLys: 1.039 ± 0.495
1.871MetLeu: 1.871 ± 0.522
0.416MetMet: 0.416 ± 0.372
0.624MetAsn: 0.624 ± 0.332
0.416MetPro: 0.416 ± 0.223
1.039MetGln: 1.039 ± 0.57
2.079MetArg: 2.079 ± 0.65
3.118MetSer: 3.118 ± 0.542
1.663MetThr: 1.663 ± 0.348
1.455MetVal: 1.455 ± 0.402
0.416MetTrp: 0.416 ± 0.22
1.039MetTyr: 1.039 ± 0.391
0.0MetXaa: 0.0 ± 0.0
Asn
3.118AsnAla: 3.118 ± 1.215
1.247AsnCys: 1.247 ± 0.363
2.286AsnAsp: 2.286 ± 0.738
1.039AsnGlu: 1.039 ± 0.527
1.247AsnPhe: 1.247 ± 0.421
3.534AsnGly: 3.534 ± 0.607
0.624AsnHis: 0.624 ± 0.227
4.573AsnIle: 4.573 ± 1.197
1.455AsnLys: 1.455 ± 0.27
4.989AsnLeu: 4.989 ± 1.03
0.416AsnMet: 0.416 ± 0.486
1.039AsnAsn: 1.039 ± 0.404
2.91AsnPro: 2.91 ± 0.67
2.702AsnGln: 2.702 ± 0.717
2.702AsnArg: 2.702 ± 0.399
3.741AsnSer: 3.741 ± 0.835
2.702AsnThr: 2.702 ± 0.69
1.455AsnVal: 1.455 ± 0.295
1.247AsnTrp: 1.247 ± 0.454
1.247AsnTyr: 1.247 ± 0.391
0.0AsnXaa: 0.0 ± 0.0
Pro
3.741ProAla: 3.741 ± 0.539
0.624ProCys: 0.624 ± 0.335
2.286ProAsp: 2.286 ± 0.74
2.702ProGlu: 2.702 ± 0.754
1.247ProPhe: 1.247 ± 0.281
4.781ProGly: 4.781 ± 0.558
0.831ProHis: 0.831 ± 0.274
2.702ProIle: 2.702 ± 0.509
1.455ProLys: 1.455 ± 0.555
3.949ProLeu: 3.949 ± 0.684
1.039ProMet: 1.039 ± 0.418
2.079ProAsn: 2.079 ± 0.55
2.494ProPro: 2.494 ± 1.003
3.326ProGln: 3.326 ± 0.802
1.663ProArg: 1.663 ± 0.36
2.91ProSer: 2.91 ± 0.713
3.118ProThr: 3.118 ± 1.19
2.079ProVal: 2.079 ± 0.515
0.208ProTrp: 0.208 ± 0.186
1.455ProTyr: 1.455 ± 0.457
0.0ProXaa: 0.0 ± 0.0
Gln
2.702GlnAla: 2.702 ± 0.926
0.416GlnCys: 0.416 ± 0.179
2.91GlnAsp: 2.91 ± 0.609
2.494GlnGlu: 2.494 ± 0.773
1.039GlnPhe: 1.039 ± 0.377
3.118GlnGly: 3.118 ± 0.663
1.039GlnHis: 1.039 ± 0.243
3.118GlnIle: 3.118 ± 1.207
1.455GlnLys: 1.455 ± 0.387
4.365GlnLeu: 4.365 ± 0.619
0.416GlnMet: 0.416 ± 0.214
1.455GlnAsn: 1.455 ± 0.494
2.494GlnPro: 2.494 ± 1.286
1.663GlnGln: 1.663 ± 0.548
2.286GlnArg: 2.286 ± 0.571
3.326GlnSer: 3.326 ± 0.55
2.079GlnThr: 2.079 ± 0.639
4.365GlnVal: 4.365 ± 0.947
0.0GlnTrp: 0.0 ± 0.0
2.079GlnTyr: 2.079 ± 0.549
0.0GlnXaa: 0.0 ± 0.0
Arg
3.741ArgAla: 3.741 ± 0.671
1.455ArgCys: 1.455 ± 0.397
2.286ArgAsp: 2.286 ± 0.885
3.326ArgGlu: 3.326 ± 1.401
1.663ArgPhe: 1.663 ± 0.488
2.702ArgGly: 2.702 ± 0.67
1.039ArgHis: 1.039 ± 0.268
2.91ArgIle: 2.91 ± 0.426
2.494ArgLys: 2.494 ± 0.702
6.859ArgLeu: 6.859 ± 0.895
1.247ArgMet: 1.247 ± 0.396
2.702ArgAsn: 2.702 ± 0.473
1.455ArgPro: 1.455 ± 0.495
2.702ArgGln: 2.702 ± 0.69
3.118ArgArg: 3.118 ± 0.695
3.534ArgSer: 3.534 ± 1.247
2.702ArgThr: 2.702 ± 0.77
5.612ArgVal: 5.612 ± 0.848
0.416ArgTrp: 0.416 ± 0.486
1.247ArgTyr: 1.247 ± 0.423
0.0ArgXaa: 0.0 ± 0.0
Ser
6.444SerAla: 6.444 ± 1.356
1.455SerCys: 1.455 ± 0.31
3.326SerAsp: 3.326 ± 0.713
5.196SerGlu: 5.196 ± 0.754
2.494SerPhe: 2.494 ± 0.715
4.365SerGly: 4.365 ± 0.683
2.286SerHis: 2.286 ± 0.641
7.483SerIle: 7.483 ± 1.169
3.326SerLys: 3.326 ± 0.815
8.73SerLeu: 8.73 ± 1.251
2.286SerMet: 2.286 ± 0.359
4.157SerAsn: 4.157 ± 0.857
3.534SerPro: 3.534 ± 0.657
3.949SerGln: 3.949 ± 0.609
3.949SerArg: 3.949 ± 0.933
6.651SerSer: 6.651 ± 0.889
4.573SerThr: 4.573 ± 0.653
3.326SerVal: 3.326 ± 0.631
1.247SerTrp: 1.247 ± 0.309
2.079SerTyr: 2.079 ± 0.549
0.0SerXaa: 0.0 ± 0.0
Thr
4.157ThrAla: 4.157 ± 0.694
1.455ThrCys: 1.455 ± 0.468
3.741ThrAsp: 3.741 ± 0.66
4.157ThrGlu: 4.157 ± 0.491
1.455ThrPhe: 1.455 ± 0.375
3.949ThrGly: 3.949 ± 0.514
1.247ThrHis: 1.247 ± 0.454
5.612ThrIle: 5.612 ± 0.755
3.118ThrLys: 3.118 ± 0.647
6.651ThrLeu: 6.651 ± 0.636
1.871ThrMet: 1.871 ± 0.648
3.326ThrAsn: 3.326 ± 0.65
4.573ThrPro: 4.573 ± 0.699
3.326ThrGln: 3.326 ± 2.088
2.91ThrArg: 2.91 ± 0.686
4.157ThrSer: 4.157 ± 0.783
4.781ThrThr: 4.781 ± 0.411
5.612ThrVal: 5.612 ± 1.229
1.247ThrTrp: 1.247 ± 0.432
0.624ThrTyr: 0.624 ± 0.227
0.208ThrXaa: 0.208 ± 0.233
Val
6.651ValAla: 6.651 ± 0.643
1.871ValCys: 1.871 ± 0.407
1.455ValAsp: 1.455 ± 0.296
4.573ValGlu: 4.573 ± 0.561
2.286ValPhe: 2.286 ± 0.472
5.612ValGly: 5.612 ± 0.812
0.416ValHis: 0.416 ± 0.352
3.326ValIle: 3.326 ± 0.738
2.286ValLys: 2.286 ± 0.509
6.236ValLeu: 6.236 ± 1.253
1.455ValMet: 1.455 ± 0.413
3.118ValAsn: 3.118 ± 1.012
1.871ValPro: 1.871 ± 0.522
2.91ValGln: 2.91 ± 0.56
4.365ValArg: 4.365 ± 0.665
6.028ValSer: 6.028 ± 0.368
5.404ValThr: 5.404 ± 0.588
4.157ValVal: 4.157 ± 1.062
0.624ValTrp: 0.624 ± 0.366
2.079ValTyr: 2.079 ± 0.432
0.0ValXaa: 0.0 ± 0.0
Trp
0.831TrpAla: 0.831 ± 0.286
0.624TrpCys: 0.624 ± 0.211
0.624TrpAsp: 0.624 ± 0.335
0.416TrpGlu: 0.416 ± 0.212
0.416TrpPhe: 0.416 ± 0.223
1.039TrpGly: 1.039 ± 0.285
0.0TrpHis: 0.0 ± 0.0
0.831TrpIle: 0.831 ± 0.294
0.416TrpLys: 0.416 ± 0.22
0.831TrpLeu: 0.831 ± 0.22
0.208TrpMet: 0.208 ± 0.112
0.624TrpAsn: 0.624 ± 0.227
0.416TrpPro: 0.416 ± 0.175
0.0TrpGln: 0.0 ± 0.0
0.831TrpArg: 0.831 ± 0.35
0.831TrpSer: 0.831 ± 0.344
0.624TrpThr: 0.624 ± 0.227
1.039TrpVal: 1.039 ± 0.614
0.416TrpTrp: 0.416 ± 0.175
0.624TrpTyr: 0.624 ± 0.335
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.91TyrAla: 2.91 ± 0.713
1.039TyrCys: 1.039 ± 0.396
0.831TyrAsp: 0.831 ± 0.303
1.247TyrGlu: 1.247 ± 0.299
1.247TyrPhe: 1.247 ± 0.329
0.831TyrGly: 0.831 ± 0.294
0.208TyrHis: 0.208 ± 0.217
1.871TyrIle: 1.871 ± 0.807
0.831TyrLys: 0.831 ± 0.334
2.079TyrLeu: 2.079 ± 0.501
0.416TyrMet: 0.416 ± 0.214
1.871TyrAsn: 1.871 ± 0.281
2.286TyrPro: 2.286 ± 0.503
1.455TyrGln: 1.455 ± 0.549
1.455TyrArg: 1.455 ± 0.458
3.326TyrSer: 3.326 ± 0.719
2.702TyrThr: 2.702 ± 0.511
1.871TyrVal: 1.871 ± 0.559
0.0TyrTrp: 0.0 ± 0.0
1.039TyrTyr: 1.039 ± 0.394
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.208XaaLeu: 0.208 ± 0.233
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
6.444XaaXaa: 6.444 ± 7.209
Statistics based on 7 proteins (4812 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski