Amino acid dipepetide frequency for Bosea caraganae

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	18.726AlaAla: 18.726 ± 0.143	1.037AlaCys: 1.037 ± 0.025	6.362AlaAsp: 6.362 ± 0.057	7.998AlaGlu: 7.998 ± 0.08	4.747AlaPhe: 4.747 ± 0.058	12.04AlaGly: 12.04 ± 0.117	2.185AlaHis: 2.185 ± 0.04	6.981AlaIle: 6.981 ± 0.075	4.502AlaLys: 4.502 ± 0.071	15.212AlaLeu: 15.212 ± 0.135	3.65AlaMet: 3.65 ± 0.044	2.985AlaAsn: 2.985 ± 0.044	6.064AlaPro: 6.064 ± 0.07	4.335AlaGln: 4.335 ± 0.06	9.109AlaArg: 9.109 ± 0.099	6.925AlaSer: 6.925 ± 0.069	6.44AlaThr: 6.44 ± 0.083	9.157AlaVal: 9.157 ± 0.085	1.537AlaTrp: 1.537 ± 0.032	2.607AlaTyr: 2.607 ± 0.039	0.0AlaXaa: 0.0 ± 0.0
Cys	0.916CysAla: 0.916 ± 0.023	0.102CysCys: 0.102 ± 0.008	0.462CysAsp: 0.462 ± 0.017	0.421CysGlu: 0.421 ± 0.017	0.31CysPhe: 0.31 ± 0.014	0.85CysGly: 0.85 ± 0.023	0.191CysHis: 0.191 ± 0.01	0.374CysIle: 0.374 ± 0.014	0.163CysLys: 0.163 ± 0.009	0.791CysLeu: 0.791 ± 0.021	0.131CysMet: 0.131 ± 0.008	0.177CysAsn: 0.177 ± 0.011	0.379CysPro: 0.379 ± 0.016	0.198CysGln: 0.198 ± 0.011	0.573CysArg: 0.573 ± 0.021	0.396CysSer: 0.396 ± 0.016	0.361CysThr: 0.361 ± 0.016	0.557CysVal: 0.557 ± 0.019	0.096CysTrp: 0.096 ± 0.008	0.156CysTyr: 0.156 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	6.761AspAla: 6.761 ± 0.077	0.409AspCys: 0.409 ± 0.017	2.753AspAsp: 2.753 ± 0.053	3.352AspGlu: 3.352 ± 0.049	2.061AspPhe: 2.061 ± 0.037	5.233AspGly: 5.233 ± 0.068	1.097AspHis: 1.097 ± 0.026	2.94AspIle: 2.94 ± 0.043	1.74AspLys: 1.74 ± 0.034	5.702AspLeu: 5.702 ± 0.059	1.105AspMet: 1.105 ± 0.025	1.089AspAsn: 1.089 ± 0.025	3.377AspPro: 3.377 ± 0.046	1.541AspGln: 1.541 ± 0.031	3.795AspArg: 3.795 ± 0.048	2.056AspSer: 2.056 ± 0.035	2.223AspThr: 2.223 ± 0.041	3.85AspVal: 3.85 ± 0.046	0.9AspTrp: 0.9 ± 0.025	1.338AspTyr: 1.338 ± 0.031	0.0AspXaa: 0.0 ± 0.0
Glu	8.261GluAla: 8.261 ± 0.088	0.323GluCys: 0.323 ± 0.014	2.352GluAsp: 2.352 ± 0.04	2.829GluGlu: 2.829 ± 0.054	1.739GluPhe: 1.739 ± 0.032	4.032GluGly: 4.032 ± 0.05	1.109GluHis: 1.109 ± 0.025	3.478GluIle: 3.478 ± 0.047	1.933GluLys: 1.933 ± 0.04	5.446GluLeu: 5.446 ± 0.056	1.427GluMet: 1.427 ± 0.032	1.284GluAsn: 1.284 ± 0.027	2.984GluPro: 2.984 ± 0.042	2.009GluGln: 2.009 ± 0.032	5.297GluArg: 5.297 ± 0.066	2.295GluSer: 2.295 ± 0.037	3.324GluThr: 3.324 ± 0.045	3.566GluVal: 3.566 ± 0.048	0.588GluTrp: 0.588 ± 0.018	0.879GluTyr: 0.879 ± 0.023	0.0GluXaa: 0.0 ± 0.0
Phe	4.973PheAla: 4.973 ± 0.056	0.362PheCys: 0.362 ± 0.013	2.527PheAsp: 2.527 ± 0.04	2.058PheGlu: 2.058 ± 0.032	1.349PhePhe: 1.349 ± 0.033	3.85PheGly: 3.85 ± 0.052	0.73PheHis: 0.73 ± 0.02	1.679PheIle: 1.679 ± 0.031	1.09PheLys: 1.09 ± 0.025	3.284PheLeu: 3.284 ± 0.047	0.815PheMet: 0.815 ± 0.024	1.022PheAsn: 1.022 ± 0.026	1.618PhePro: 1.618 ± 0.03	1.014PheGln: 1.014 ± 0.025	2.26PheArg: 2.26 ± 0.038	2.124PheSer: 2.124 ± 0.039	1.931PheThr: 1.931 ± 0.038	2.968PheVal: 2.968 ± 0.042	0.563PheTrp: 0.563 ± 0.018	0.81PheTyr: 0.81 ± 0.022	0.0PheXaa: 0.0 ± 0.0
Gly	10.236GlyAla: 10.236 ± 0.126	0.796GlyCys: 0.796 ± 0.019	4.301GlyAsp: 4.301 ± 0.063	5.001GlyGlu: 5.001 ± 0.054	3.792GlyPhe: 3.792 ± 0.052	8.078GlyGly: 8.078 ± 0.165	1.864GlyHis: 1.864 ± 0.04	4.715GlyIle: 4.715 ± 0.053	3.386GlyLys: 3.386 ± 0.049	9.857GlyLeu: 9.857 ± 0.083	2.195GlyMet: 2.195 ± 0.04	2.234GlyAsn: 2.234 ± 0.059	3.766GlyPro: 3.766 ± 0.052	2.943GlyGln: 2.943 ± 0.047	6.462GlyArg: 6.462 ± 0.073	5.111GlySer: 5.111 ± 0.089	4.807GlyThr: 4.807 ± 0.114	6.051GlyVal: 6.051 ± 0.061	1.369GlyTrp: 1.369 ± 0.032	2.323GlyTyr: 2.323 ± 0.039	0.0GlyXaa: 0.0 ± 0.0
His	2.3HisAla: 2.3 ± 0.036	0.186HisCys: 0.186 ± 0.011	1.209HisAsp: 1.209 ± 0.027	1.011HisGlu: 1.011 ± 0.024	0.753HisPhe: 0.753 ± 0.024	1.902HisGly: 1.902 ± 0.036	0.504HisHis: 0.504 ± 0.019	0.819HisIle: 0.819 ± 0.021	0.437HisLys: 0.437 ± 0.018	2.03HisLeu: 2.03 ± 0.037	0.4HisMet: 0.4 ± 0.017	0.395HisAsn: 0.395 ± 0.014	1.213HisPro: 1.213 ± 0.026	0.499HisGln: 0.499 ± 0.018	1.271HisArg: 1.271 ± 0.029	0.83HisSer: 0.83 ± 0.021	0.699HisThr: 0.699 ± 0.021	1.485HisVal: 1.485 ± 0.035	0.319HisTrp: 0.319 ± 0.014	0.483HisTyr: 0.483 ± 0.018	0.0HisXaa: 0.0 ± 0.0
Ile	8.051IleAla: 8.051 ± 0.072	0.483IleCys: 0.483 ± 0.017	3.443IleAsp: 3.443 ± 0.05	3.391IleGlu: 3.391 ± 0.043	1.629IlePhe: 1.629 ± 0.032	5.384IleGly: 5.384 ± 0.066	0.839IleHis: 0.839 ± 0.02	2.239IleIle: 2.239 ± 0.047	1.479IleLys: 1.479 ± 0.03	4.495IleLeu: 4.495 ± 0.055	0.954IleMet: 0.954 ± 0.025	1.256IleAsn: 1.256 ± 0.029	2.38IlePro: 2.38 ± 0.039	1.159IleGln: 1.159 ± 0.026	3.17IleArg: 3.17 ± 0.041	2.854IleSer: 2.854 ± 0.043	2.593IleThr: 2.593 ± 0.039	4.571IleVal: 4.571 ± 0.06	0.598IleTrp: 0.598 ± 0.016	1.051IleTyr: 1.051 ± 0.021	0.0IleXaa: 0.0 ± 0.0
Lys	4.703LysAla: 4.703 ± 0.06	0.126LysCys: 0.126 ± 0.01	1.6LysAsp: 1.6 ± 0.031	1.478LysGlu: 1.478 ± 0.035	0.841LysPhe: 0.841 ± 0.023	2.635LysGly: 2.635 ± 0.041	0.537LysHis: 0.537 ± 0.017	1.613LysIle: 1.613 ± 0.034	1.026LysLys: 1.026 ± 0.028	3.782LysLeu: 3.782 ± 0.045	0.617LysMet: 0.617 ± 0.02	0.759LysAsn: 0.759 ± 0.02	2.391LysPro: 2.391 ± 0.044	1.043LysGln: 1.043 ± 0.027	2.387LysArg: 2.387 ± 0.042	1.702LysSer: 1.702 ± 0.033	1.837LysThr: 1.837 ± 0.039	2.462LysVal: 2.462 ± 0.043	0.301LysTrp: 0.301 ± 0.013	0.522LysTyr: 0.522 ± 0.019	0.0LysXaa: 0.0 ± 0.0
Leu	15.36LeuAla: 15.36 ± 0.113	0.839LeuCys: 0.839 ± 0.023	6.234LeuAsp: 6.234 ± 0.072	4.823LeuGlu: 4.823 ± 0.062	3.656LeuPhe: 3.656 ± 0.056	9.194LeuGly: 9.194 ± 0.083	1.748LeuHis: 1.748 ± 0.033	5.37LeuIle: 5.37 ± 0.062	3.819LeuLys: 3.819 ± 0.045	10.066LeuLeu: 10.066 ± 0.135	2.252LeuMet: 2.252 ± 0.035	2.531LeuAsn: 2.531 ± 0.043	6.015LeuPro: 6.015 ± 0.068	2.664LeuGln: 2.664 ± 0.036	7.044LeuArg: 7.044 ± 0.07	6.644LeuSer: 6.644 ± 0.058	5.729LeuThr: 5.729 ± 0.065	8.005LeuVal: 8.005 ± 0.085	1.213LeuTrp: 1.213 ± 0.028	2.01LeuTyr: 2.01 ± 0.033	0.0LeuXaa: 0.0 ± 0.0
Met	3.084MetAla: 3.084 ± 0.043	0.132MetCys: 0.132 ± 0.009	0.963MetAsp: 0.963 ± 0.025	0.883MetGlu: 0.883 ± 0.023	0.631MetPhe: 0.631 ± 0.019	1.675MetGly: 1.675 ± 0.027	0.392MetHis: 0.392 ± 0.016	1.311MetIle: 1.311 ± 0.03	0.848MetLys: 0.848 ± 0.023	2.564MetLeu: 2.564 ± 0.044	0.569MetMet: 0.569 ± 0.021	0.682MetAsn: 0.682 ± 0.019	1.479MetPro: 1.479 ± 0.029	0.752MetGln: 0.752 ± 0.021	1.838MetArg: 1.838 ± 0.033	1.631MetSer: 1.631 ± 0.029	1.759MetThr: 1.759 ± 0.03	1.64MetVal: 1.64 ± 0.031	0.177MetTrp: 0.177 ± 0.01	0.278MetTyr: 0.278 ± 0.012	0.0MetXaa: 0.0 ± 0.0
Asn	3.174AsnAla: 3.174 ± 0.044	0.184AsnCys: 0.184 ± 0.012	1.267AsnAsp: 1.267 ± 0.036	1.149AsnGlu: 1.149 ± 0.028	0.885AsnPhe: 0.885 ± 0.023	2.366AsnGly: 2.366 ± 0.053	0.434AsnHis: 0.434 ± 0.015	1.186AsnIle: 1.186 ± 0.03	0.667AsnLys: 0.667 ± 0.018	2.623AsnLeu: 2.623 ± 0.043	0.494AsnMet: 0.494 ± 0.017	0.696AsnAsn: 0.696 ± 0.025	1.737AsnPro: 1.737 ± 0.03	0.703AsnGln: 0.703 ± 0.02	1.633AsnArg: 1.633 ± 0.03	1.203AsnSer: 1.203 ± 0.029	1.161AsnThr: 1.161 ± 0.036	1.842AsnVal: 1.842 ± 0.038	0.433AsnTrp: 0.433 ± 0.018	0.624AsnTyr: 0.624 ± 0.016	0.0AsnXaa: 0.0 ± 0.0
Pro	7.175ProAla: 7.175 ± 0.07	0.289ProCys: 0.289 ± 0.015	3.403ProAsp: 3.403 ± 0.046	3.723ProGlu: 3.723 ± 0.062	2.039ProPhe: 2.039 ± 0.034	4.851ProGly: 4.851 ± 0.056	1.007ProHis: 1.007 ± 0.025	2.381ProIle: 2.381 ± 0.036	1.708ProLys: 1.708 ± 0.032	5.049ProLeu: 5.049 ± 0.06	1.182ProMet: 1.182 ± 0.026	1.37ProAsn: 1.37 ± 0.03	2.796ProPro: 2.796 ± 0.055	1.726ProGln: 1.726 ± 0.029	3.185ProArg: 3.185 ± 0.05	2.89ProSer: 2.89 ± 0.042	2.457ProThr: 2.457 ± 0.036	4.252ProVal: 4.252 ± 0.05	0.676ProTrp: 0.676 ± 0.023	1.197ProTyr: 1.197 ± 0.032	0.0ProXaa: 0.0 ± 0.0
Gln	4.525GlnAla: 4.525 ± 0.059	0.17GlnCys: 0.17 ± 0.011	1.39GlnAsp: 1.39 ± 0.027	1.332GlnGlu: 1.332 ± 0.029	1.05GlnPhe: 1.05 ± 0.024	2.472GlnGly: 2.472 ± 0.041	0.572GlnHis: 0.572 ± 0.019	1.767GlnIle: 1.767 ± 0.032	0.998GlnLys: 0.998 ± 0.026	2.883GlnLeu: 2.883 ± 0.046	0.783GlnMet: 0.783 ± 0.021	0.845GlnAsn: 0.845 ± 0.025	1.829GlnPro: 1.829 ± 0.033	1.217GlnGln: 1.217 ± 0.032	2.6GlnArg: 2.6 ± 0.046	1.704GlnSer: 1.704 ± 0.034	1.561GlnThr: 1.561 ± 0.029	2.293GlnVal: 2.293 ± 0.038	0.335GlnTrp: 0.335 ± 0.015	0.552GlnTyr: 0.552 ± 0.019	0.0GlnXaa: 0.0 ± 0.0
Arg	8.015ArgAla: 8.015 ± 0.084	0.508ArgCys: 0.508 ± 0.018	3.975ArgAsp: 3.975 ± 0.059	4.191ArgGlu: 4.191 ± 0.058	3.015ArgPhe: 3.015 ± 0.039	5.011ArgGly: 5.011 ± 0.053	1.636ArgHis: 1.636 ± 0.032	3.976ArgIle: 3.976 ± 0.046	2.234ArgLys: 2.234 ± 0.042	8.122ArgLeu: 8.122 ± 0.068	1.792ArgMet: 1.792 ± 0.037	1.771ArgAsn: 1.771 ± 0.032	3.796ArgPro: 3.796 ± 0.055	2.623ArgGln: 2.623 ± 0.041	5.728ArgArg: 5.728 ± 0.078	3.86ArgSer: 3.86 ± 0.055	3.175ArgThr: 3.175 ± 0.04	4.66ArgVal: 4.66 ± 0.054	0.961ArgTrp: 0.961 ± 0.025	1.662ArgTyr: 1.662 ± 0.029	0.0ArgXaa: 0.0 ± 0.0
Ser	6.541SerAla: 6.541 ± 0.073	0.395SerCys: 0.395 ± 0.018	2.8SerAsp: 2.8 ± 0.043	2.782SerGlu: 2.782 ± 0.042	2.508SerPhe: 2.508 ± 0.039	5.901SerGly: 5.901 ± 0.09	1.023SerHis: 1.023 ± 0.023	2.588SerIle: 2.588 ± 0.04	1.511SerLys: 1.511 ± 0.031	5.783SerLeu: 5.783 ± 0.062	1.19SerMet: 1.19 ± 0.022	1.288SerAsn: 1.288 ± 0.028	2.822SerPro: 2.822 ± 0.046	1.661SerGln: 1.661 ± 0.038	3.66SerArg: 3.66 ± 0.048	2.968SerSer: 2.968 ± 0.047	2.659SerThr: 2.659 ± 0.046	4.017SerVal: 4.017 ± 0.05	0.794SerTrp: 0.794 ± 0.021	1.302SerTyr: 1.302 ± 0.029	0.0SerXaa: 0.0 ± 0.0
Thr	6.279ThrAla: 6.279 ± 0.076	0.398ThrCys: 0.398 ± 0.016	2.43ThrAsp: 2.43 ± 0.039	2.558ThrGlu: 2.558 ± 0.046	1.871ThrPhe: 1.871 ± 0.035	5.142ThrGly: 5.142 ± 0.095	0.931ThrHis: 0.931 ± 0.025	3.128ThrIle: 3.128 ± 0.043	1.417ThrLys: 1.417 ± 0.03	6.114ThrLeu: 6.114 ± 0.079	1.185ThrMet: 1.185 ± 0.027	1.21ThrAsn: 1.21 ± 0.034	3.128ThrPro: 3.128 ± 0.042	1.471ThrGln: 1.471 ± 0.027	3.294ThrArg: 3.294 ± 0.042	2.72ThrSer: 2.72 ± 0.041	2.824ThrThr: 2.824 ± 0.051	4.114ThrVal: 4.114 ± 0.057	0.653ThrTrp: 0.653 ± 0.022	1.145ThrTyr: 1.145 ± 0.025	0.0ThrXaa: 0.0 ± 0.0
Val	9.816ValAla: 9.816 ± 0.073	0.537ValCys: 0.537 ± 0.018	3.913ValAsp: 3.913 ± 0.053	4.47ValGlu: 4.47 ± 0.052	2.789ValPhe: 2.789 ± 0.041	5.603ValGly: 5.603 ± 0.052	1.239ValHis: 1.239 ± 0.03	4.038ValIle: 4.038 ± 0.054	2.415ValLys: 2.415 ± 0.043	7.563ValLeu: 7.563 ± 0.085	1.862ValMet: 1.862 ± 0.031	1.906ValAsn: 1.906 ± 0.037	3.768ValPro: 3.768 ± 0.045	2.087ValGln: 2.087 ± 0.038	4.53ValArg: 4.53 ± 0.048	4.391ValSer: 4.391 ± 0.045	4.68ValThr: 4.68 ± 0.056	5.975ValVal: 5.975 ± 0.072	0.8ValTrp: 0.8 ± 0.02	1.361ValTyr: 1.361 ± 0.029	0.0ValXaa: 0.0 ± 0.0
Trp	1.176TrpAla: 1.176 ± 0.027	0.121TrpCys: 0.121 ± 0.007	0.566TrpAsp: 0.566 ± 0.021	0.515TrpGlu: 0.515 ± 0.018	0.522TrpPhe: 0.522 ± 0.02	0.954TrpGly: 0.954 ± 0.028	0.297TrpHis: 0.297 ± 0.013	0.643TrpIle: 0.643 ± 0.021	0.419TrpLys: 0.419 ± 0.016	1.688TrpLeu: 1.688 ± 0.036	0.302TrpMet: 0.302 ± 0.012	0.42TrpAsn: 0.42 ± 0.015	0.726TrpPro: 0.726 ± 0.022	0.565TrpGln: 0.565 ± 0.019	1.174TrpArg: 1.174 ± 0.027	0.805TrpSer: 0.805 ± 0.024	0.788TrpThr: 0.788 ± 0.02	0.714TrpVal: 0.714 ± 0.018	0.229TrpTrp: 0.229 ± 0.01	0.28TrpTyr: 0.28 ± 0.014	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.529TyrAla: 2.529 ± 0.041	0.208TyrCys: 0.208 ± 0.011	1.372TyrAsp: 1.372 ± 0.027	1.19TyrGlu: 1.19 ± 0.027	0.838TyrPhe: 0.838 ± 0.023	2.114TyrGly: 2.114 ± 0.038	0.41TyrHis: 0.41 ± 0.014	0.792TyrIle: 0.792 ± 0.022	0.57TyrLys: 0.57 ± 0.021	2.16TyrLeu: 2.16 ± 0.035	0.382TyrMet: 0.382 ± 0.014	0.538TyrAsn: 0.538 ± 0.018	1.087TyrPro: 1.087 ± 0.029	0.667TyrGln: 0.667 ± 0.018	1.704TyrArg: 1.704 ± 0.03	1.085TyrSer: 1.085 ± 0.027	1.006TyrThr: 1.006 ± 0.027	1.565TyrVal: 1.565 ± 0.031	0.364TyrTrp: 0.364 ± 0.015	0.527TyrTyr: 0.527 ± 0.019	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 5639 proteins (1791978 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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