Amino acid dipepetide frequency for Beihai picorna-like virus 99

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.82AlaAla: 3.82 ± 0.0
0.955AlaCys: 0.955 ± 0.0
2.865AlaAsp: 2.865 ± 0.0
2.865AlaGlu: 2.865 ± 0.0
1.91AlaPhe: 1.91 ± 0.0
3.82AlaGly: 3.82 ± 0.0
1.433AlaHis: 1.433 ± 0.0
4.776AlaIle: 4.776 ± 0.0
5.253AlaLys: 5.253 ± 0.0
7.641AlaLeu: 7.641 ± 0.0
1.91AlaMet: 1.91 ± 0.0
3.82AlaAsn: 3.82 ± 0.0
4.776AlaPro: 4.776 ± 0.0
4.298AlaGln: 4.298 ± 0.0
2.388AlaArg: 2.388 ± 0.0
4.776AlaSer: 4.776 ± 0.0
5.253AlaThr: 5.253 ± 0.0
5.731AlaVal: 5.731 ± 0.0
0.0AlaTrp: 0.0 ± 0.0
3.82AlaTyr: 3.82 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
3.82CysAla: 3.82 ± 0.0
0.478CysCys: 0.478 ± 0.0
1.433CysAsp: 1.433 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.955CysPhe: 0.955 ± 0.0
0.955CysGly: 0.955 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.478CysIle: 0.478 ± 0.0
0.478CysLys: 0.478 ± 0.0
0.0CysLeu: 0.0 ± 0.0
0.478CysMet: 0.478 ± 0.0
0.955CysAsn: 0.955 ± 0.0
1.433CysPro: 1.433 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
2.388CysSer: 2.388 ± 0.0
0.478CysThr: 0.478 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.955CysTyr: 0.955 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
5.253AspAla: 5.253 ± 0.0
0.955AspCys: 0.955 ± 0.0
3.82AspAsp: 3.82 ± 0.0
4.776AspGlu: 4.776 ± 0.0
1.91AspPhe: 1.91 ± 0.0
1.91AspGly: 1.91 ± 0.0
0.955AspHis: 0.955 ± 0.0
2.388AspIle: 2.388 ± 0.0
3.343AspLys: 3.343 ± 0.0
8.118AspLeu: 8.118 ± 0.0
1.433AspMet: 1.433 ± 0.0
1.433AspAsn: 1.433 ± 0.0
3.82AspPro: 3.82 ± 0.0
0.955AspGln: 0.955 ± 0.0
0.955AspArg: 0.955 ± 0.0
4.298AspSer: 4.298 ± 0.0
4.298AspThr: 4.298 ± 0.0
3.82AspVal: 3.82 ± 0.0
2.388AspTrp: 2.388 ± 0.0
2.388AspTyr: 2.388 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
4.298GluAla: 4.298 ± 0.0
1.433GluCys: 1.433 ± 0.0
1.433GluAsp: 1.433 ± 0.0
3.82GluGlu: 3.82 ± 0.0
1.91GluPhe: 1.91 ± 0.0
5.253GluGly: 5.253 ± 0.0
1.91GluHis: 1.91 ± 0.0
2.865GluIle: 2.865 ± 0.0
4.298GluLys: 4.298 ± 0.0
3.82GluLeu: 3.82 ± 0.0
0.955GluMet: 0.955 ± 0.0
1.91GluAsn: 1.91 ± 0.0
0.955GluPro: 0.955 ± 0.0
2.865GluGln: 2.865 ± 0.0
1.91GluArg: 1.91 ± 0.0
1.91GluSer: 1.91 ± 0.0
1.433GluThr: 1.433 ± 0.0
3.82GluVal: 3.82 ± 0.0
0.955GluTrp: 0.955 ± 0.0
3.343GluTyr: 3.343 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
2.865PheAla: 2.865 ± 0.0
1.433PheCys: 1.433 ± 0.0
4.776PheAsp: 4.776 ± 0.0
1.91PheGlu: 1.91 ± 0.0
2.388PhePhe: 2.388 ± 0.0
4.776PheGly: 4.776 ± 0.0
0.955PheHis: 0.955 ± 0.0
1.433PheIle: 1.433 ± 0.0
2.865PheLys: 2.865 ± 0.0
3.343PheLeu: 3.343 ± 0.0
2.388PheMet: 2.388 ± 0.0
1.433PheAsn: 1.433 ± 0.0
0.478PhePro: 0.478 ± 0.0
4.776PheGln: 4.776 ± 0.0
3.343PheArg: 3.343 ± 0.0
3.343PheSer: 3.343 ± 0.0
2.865PheThr: 2.865 ± 0.0
4.298PheVal: 4.298 ± 0.0
0.955PheTrp: 0.955 ± 0.0
1.433PheTyr: 1.433 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
5.731GlyAla: 5.731 ± 0.0
0.955GlyCys: 0.955 ± 0.0
3.82GlyAsp: 3.82 ± 0.0
1.433GlyGlu: 1.433 ± 0.0
2.388GlyPhe: 2.388 ± 0.0
3.82GlyGly: 3.82 ± 0.0
0.478GlyHis: 0.478 ± 0.0
3.343GlyIle: 3.343 ± 0.0
5.253GlyLys: 5.253 ± 0.0
5.731GlyLeu: 5.731 ± 0.0
0.955GlyMet: 0.955 ± 0.0
0.955GlyAsn: 0.955 ± 0.0
3.343GlyPro: 3.343 ± 0.0
1.91GlyGln: 1.91 ± 0.0
1.91GlyArg: 1.91 ± 0.0
3.343GlySer: 3.343 ± 0.0
3.82GlyThr: 3.82 ± 0.0
6.686GlyVal: 6.686 ± 0.0
1.91GlyTrp: 1.91 ± 0.0
1.433GlyTyr: 1.433 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
0.478HisAla: 0.478 ± 0.0
0.955HisCys: 0.955 ± 0.0
0.955HisAsp: 0.955 ± 0.0
0.478HisGlu: 0.478 ± 0.0
1.433HisPhe: 1.433 ± 0.0
0.478HisGly: 0.478 ± 0.0
0.955HisHis: 0.955 ± 0.0
1.433HisIle: 1.433 ± 0.0
0.478HisLys: 0.478 ± 0.0
2.388HisLeu: 2.388 ± 0.0
0.955HisMet: 0.955 ± 0.0
0.0HisAsn: 0.0 ± 0.0
1.91HisPro: 1.91 ± 0.0
0.478HisGln: 0.478 ± 0.0
0.478HisArg: 0.478 ± 0.0
0.0HisSer: 0.0 ± 0.0
2.388HisThr: 2.388 ± 0.0
3.343HisVal: 3.343 ± 0.0
0.478HisTrp: 0.478 ± 0.0
0.955HisTyr: 0.955 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
4.298IleAla: 4.298 ± 0.0
0.478IleCys: 0.478 ± 0.0
1.433IleAsp: 1.433 ± 0.0
4.298IleGlu: 4.298 ± 0.0
2.865IlePhe: 2.865 ± 0.0
2.865IleGly: 2.865 ± 0.0
1.91IleHis: 1.91 ± 0.0
1.433IleIle: 1.433 ± 0.0
1.433IleLys: 1.433 ± 0.0
5.253IleLeu: 5.253 ± 0.0
0.955IleMet: 0.955 ± 0.0
4.298IleAsn: 4.298 ± 0.0
3.82IlePro: 3.82 ± 0.0
1.433IleGln: 1.433 ± 0.0
1.91IleArg: 1.91 ± 0.0
2.388IleSer: 2.388 ± 0.0
3.82IleThr: 3.82 ± 0.0
4.298IleVal: 4.298 ± 0.0
0.0IleTrp: 0.0 ± 0.0
1.433IleTyr: 1.433 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
2.388LysAla: 2.388 ± 0.0
1.433LysCys: 1.433 ± 0.0
3.343LysAsp: 3.343 ± 0.0
2.388LysGlu: 2.388 ± 0.0
2.865LysPhe: 2.865 ± 0.0
4.298LysGly: 4.298 ± 0.0
0.478LysHis: 0.478 ± 0.0
4.776LysIle: 4.776 ± 0.0
5.253LysLys: 5.253 ± 0.0
5.731LysLeu: 5.731 ± 0.0
2.865LysMet: 2.865 ± 0.0
3.343LysAsn: 3.343 ± 0.0
2.388LysPro: 2.388 ± 0.0
2.865LysGln: 2.865 ± 0.0
4.298LysArg: 4.298 ± 0.0
3.343LysSer: 3.343 ± 0.0
2.865LysThr: 2.865 ± 0.0
3.82LysVal: 3.82 ± 0.0
0.478LysTrp: 0.478 ± 0.0
0.478LysTyr: 0.478 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
5.731LeuAla: 5.731 ± 0.0
0.955LeuCys: 0.955 ± 0.0
5.253LeuAsp: 5.253 ± 0.0
5.731LeuGlu: 5.731 ± 0.0
3.343LeuPhe: 3.343 ± 0.0
4.776LeuGly: 4.776 ± 0.0
1.91LeuHis: 1.91 ± 0.0
4.298LeuIle: 4.298 ± 0.0
7.641LeuLys: 7.641 ± 0.0
4.776LeuLeu: 4.776 ± 0.0
2.388LeuMet: 2.388 ± 0.0
3.343LeuAsn: 3.343 ± 0.0
7.163LeuPro: 7.163 ± 0.0
0.955LeuGln: 0.955 ± 0.0
3.343LeuArg: 3.343 ± 0.0
9.551LeuSer: 9.551 ± 0.0
4.298LeuThr: 4.298 ± 0.0
5.731LeuVal: 5.731 ± 0.0
0.0LeuTrp: 0.0 ± 0.0
4.298LeuTyr: 4.298 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
1.433MetAla: 1.433 ± 0.0
0.478MetCys: 0.478 ± 0.0
1.91MetAsp: 1.91 ± 0.0
3.82MetGlu: 3.82 ± 0.0
2.388MetPhe: 2.388 ± 0.0
0.955MetGly: 0.955 ± 0.0
1.433MetHis: 1.433 ± 0.0
0.0MetIle: 0.0 ± 0.0
2.388MetLys: 2.388 ± 0.0
2.388MetLeu: 2.388 ± 0.0
0.478MetMet: 0.478 ± 0.0
2.865MetAsn: 2.865 ± 0.0
1.433MetPro: 1.433 ± 0.0
0.478MetGln: 0.478 ± 0.0
0.478MetArg: 0.478 ± 0.0
0.955MetSer: 0.955 ± 0.0
2.388MetThr: 2.388 ± 0.0
1.433MetVal: 1.433 ± 0.0
0.478MetTrp: 0.478 ± 0.0
1.433MetTyr: 1.433 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.343AsnAla: 3.343 ± 0.0
0.0AsnCys: 0.0 ± 0.0
3.343AsnAsp: 3.343 ± 0.0
2.865AsnGlu: 2.865 ± 0.0
2.865AsnPhe: 2.865 ± 0.0
3.343AsnGly: 3.343 ± 0.0
0.0AsnHis: 0.0 ± 0.0
1.91AsnIle: 1.91 ± 0.0
2.388AsnLys: 2.388 ± 0.0
3.82AsnLeu: 3.82 ± 0.0
1.433AsnMet: 1.433 ± 0.0
0.478AsnAsn: 0.478 ± 0.0
2.865AsnPro: 2.865 ± 0.0
1.91AsnGln: 1.91 ± 0.0
1.91AsnArg: 1.91 ± 0.0
1.91AsnSer: 1.91 ± 0.0
2.865AsnThr: 2.865 ± 0.0
4.298AsnVal: 4.298 ± 0.0
0.478AsnTrp: 0.478 ± 0.0
1.433AsnTyr: 1.433 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
5.253ProAla: 5.253 ± 0.0
0.478ProCys: 0.478 ± 0.0
2.865ProAsp: 2.865 ± 0.0
2.865ProGlu: 2.865 ± 0.0
2.865ProPhe: 2.865 ± 0.0
1.91ProGly: 1.91 ± 0.0
1.91ProHis: 1.91 ± 0.0
3.82ProIle: 3.82 ± 0.0
0.955ProLys: 0.955 ± 0.0
3.82ProLeu: 3.82 ± 0.0
1.91ProMet: 1.91 ± 0.0
0.478ProAsn: 0.478 ± 0.0
2.388ProPro: 2.388 ± 0.0
0.478ProGln: 0.478 ± 0.0
2.388ProArg: 2.388 ± 0.0
4.298ProSer: 4.298 ± 0.0
4.776ProThr: 4.776 ± 0.0
2.388ProVal: 2.388 ± 0.0
1.91ProTrp: 1.91 ± 0.0
2.865ProTyr: 2.865 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
3.343GlnAla: 3.343 ± 0.0
0.478GlnCys: 0.478 ± 0.0
1.91GlnAsp: 1.91 ± 0.0
2.388GlnGlu: 2.388 ± 0.0
0.955GlnPhe: 0.955 ± 0.0
2.388GlnGly: 2.388 ± 0.0
0.478GlnHis: 0.478 ± 0.0
1.91GlnIle: 1.91 ± 0.0
2.388GlnLys: 2.388 ± 0.0
1.91GlnLeu: 1.91 ± 0.0
0.478GlnMet: 0.478 ± 0.0
3.343GlnAsn: 3.343 ± 0.0
1.433GlnPro: 1.433 ± 0.0
2.388GlnGln: 2.388 ± 0.0
0.955GlnArg: 0.955 ± 0.0
1.91GlnSer: 1.91 ± 0.0
2.388GlnThr: 2.388 ± 0.0
3.343GlnVal: 3.343 ± 0.0
0.955GlnTrp: 0.955 ± 0.0
2.865GlnTyr: 2.865 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
0.478ArgAla: 0.478 ± 0.0
0.478ArgCys: 0.478 ± 0.0
0.955ArgAsp: 0.955 ± 0.0
0.955ArgGlu: 0.955 ± 0.0
4.298ArgPhe: 4.298 ± 0.0
1.433ArgGly: 1.433 ± 0.0
0.955ArgHis: 0.955 ± 0.0
1.433ArgIle: 1.433 ± 0.0
2.865ArgLys: 2.865 ± 0.0
4.298ArgLeu: 4.298 ± 0.0
2.865ArgMet: 2.865 ± 0.0
2.388ArgAsn: 2.388 ± 0.0
1.433ArgPro: 1.433 ± 0.0
1.91ArgGln: 1.91 ± 0.0
1.91ArgArg: 1.91 ± 0.0
2.865ArgSer: 2.865 ± 0.0
2.388ArgThr: 2.388 ± 0.0
5.253ArgVal: 5.253 ± 0.0
0.478ArgTrp: 0.478 ± 0.0
2.865ArgTyr: 2.865 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
5.253SerAla: 5.253 ± 0.0
0.955SerCys: 0.955 ± 0.0
3.82SerAsp: 3.82 ± 0.0
2.388SerGlu: 2.388 ± 0.0
6.686SerPhe: 6.686 ± 0.0
2.865SerGly: 2.865 ± 0.0
0.955SerHis: 0.955 ± 0.0
3.343SerIle: 3.343 ± 0.0
3.343SerLys: 3.343 ± 0.0
4.298SerLeu: 4.298 ± 0.0
2.388SerMet: 2.388 ± 0.0
3.343SerAsn: 3.343 ± 0.0
2.388SerPro: 2.388 ± 0.0
2.865SerGln: 2.865 ± 0.0
1.91SerArg: 1.91 ± 0.0
4.776SerSer: 4.776 ± 0.0
5.253SerThr: 5.253 ± 0.0
4.776SerVal: 4.776 ± 0.0
1.433SerTrp: 1.433 ± 0.0
3.82SerTyr: 3.82 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
4.776ThrAla: 4.776 ± 0.0
0.0ThrCys: 0.0 ± 0.0
3.82ThrAsp: 3.82 ± 0.0
3.82ThrGlu: 3.82 ± 0.0
4.776ThrPhe: 4.776 ± 0.0
3.82ThrGly: 3.82 ± 0.0
1.433ThrHis: 1.433 ± 0.0
2.388ThrIle: 2.388 ± 0.0
3.343ThrLys: 3.343 ± 0.0
3.82ThrLeu: 3.82 ± 0.0
2.388ThrMet: 2.388 ± 0.0
1.433ThrAsn: 1.433 ± 0.0
4.776ThrPro: 4.776 ± 0.0
1.91ThrGln: 1.91 ± 0.0
2.865ThrArg: 2.865 ± 0.0
4.298ThrSer: 4.298 ± 0.0
2.865ThrThr: 2.865 ± 0.0
6.208ThrVal: 6.208 ± 0.0
0.478ThrTrp: 0.478 ± 0.0
3.343ThrTyr: 3.343 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
5.731ValAla: 5.731 ± 0.0
1.91ValCys: 1.91 ± 0.0
7.641ValAsp: 7.641 ± 0.0
2.865ValGlu: 2.865 ± 0.0
3.82ValPhe: 3.82 ± 0.0
5.253ValGly: 5.253 ± 0.0
0.955ValHis: 0.955 ± 0.0
2.865ValIle: 2.865 ± 0.0
3.343ValLys: 3.343 ± 0.0
5.253ValLeu: 5.253 ± 0.0
1.433ValMet: 1.433 ± 0.0
4.776ValAsn: 4.776 ± 0.0
2.865ValPro: 2.865 ± 0.0
2.865ValGln: 2.865 ± 0.0
5.253ValArg: 5.253 ± 0.0
5.253ValSer: 5.253 ± 0.0
4.776ValThr: 4.776 ± 0.0
6.208ValVal: 6.208 ± 0.0
0.955ValTrp: 0.955 ± 0.0
3.82ValTyr: 3.82 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
1.433TrpAla: 1.433 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
0.955TrpPhe: 0.955 ± 0.0
1.91TrpGly: 1.91 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.955TrpIle: 0.955 ± 0.0
0.478TrpLys: 0.478 ± 0.0
1.91TrpLeu: 1.91 ± 0.0
0.478TrpMet: 0.478 ± 0.0
0.955TrpAsn: 0.955 ± 0.0
0.478TrpPro: 0.478 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.955TrpArg: 0.955 ± 0.0
0.955TrpSer: 0.955 ± 0.0
0.955TrpThr: 0.955 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
2.865TrpTyr: 2.865 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.388TyrAla: 2.388 ± 0.0
0.478TyrCys: 0.478 ± 0.0
3.82TyrAsp: 3.82 ± 0.0
1.433TyrGlu: 1.433 ± 0.0
0.478TyrPhe: 0.478 ± 0.0
2.388TyrGly: 2.388 ± 0.0
1.91TyrHis: 1.91 ± 0.0
4.776TyrIle: 4.776 ± 0.0
1.91TyrLys: 1.91 ± 0.0
7.163TyrLeu: 7.163 ± 0.0
0.0TyrMet: 0.0 ± 0.0
1.91TyrAsn: 1.91 ± 0.0
0.478TyrPro: 0.478 ± 0.0
2.865TyrGln: 2.865 ± 0.0
3.343TyrArg: 3.343 ± 0.0
4.776TyrSer: 4.776 ± 0.0
2.388TyrThr: 2.388 ± 0.0
2.388TyrVal: 2.388 ± 0.0
0.955TyrTrp: 0.955 ± 0.0
1.433TyrTyr: 1.433 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1 proteins (2095 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski