Amino acid dipepetide frequency for Wenzhou picorna-like virus 13

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.302AlaAla: 7.302 ± 0.0
1.739AlaCys: 1.739 ± 0.0
3.477AlaAsp: 3.477 ± 0.0
2.782AlaGlu: 2.782 ± 0.0
3.129AlaPhe: 3.129 ± 0.0
6.954AlaGly: 6.954 ± 0.0
2.434AlaHis: 2.434 ± 0.0
3.129AlaIle: 3.129 ± 0.0
2.782AlaLys: 2.782 ± 0.0
3.129AlaLeu: 3.129 ± 0.0
2.434AlaMet: 2.434 ± 0.0
3.477AlaAsn: 3.477 ± 0.0
5.216AlaPro: 5.216 ± 0.0
4.172AlaGln: 4.172 ± 0.0
3.477AlaArg: 3.477 ± 0.0
6.259AlaSer: 6.259 ± 0.0
5.563AlaThr: 5.563 ± 0.0
6.259AlaVal: 6.259 ± 0.0
0.695AlaTrp: 0.695 ± 0.0
3.477AlaTyr: 3.477 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
2.086CysAla: 2.086 ± 0.0
1.043CysCys: 1.043 ± 0.0
0.348CysAsp: 0.348 ± 0.0
1.391CysGlu: 1.391 ± 0.0
1.739CysPhe: 1.739 ± 0.0
1.391CysGly: 1.391 ± 0.0
0.348CysHis: 0.348 ± 0.0
2.086CysIle: 2.086 ± 0.0
0.0CysLys: 0.0 ± 0.0
1.739CysLeu: 1.739 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.695CysAsn: 0.695 ± 0.0
1.043CysPro: 1.043 ± 0.0
0.348CysGln: 0.348 ± 0.0
0.695CysArg: 0.695 ± 0.0
0.348CysSer: 0.348 ± 0.0
1.739CysThr: 1.739 ± 0.0
3.129CysVal: 3.129 ± 0.0
0.0CysTrp: 0.0 ± 0.0
0.695CysTyr: 0.695 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
6.259AspAla: 6.259 ± 0.0
0.0AspCys: 0.0 ± 0.0
4.172AspAsp: 4.172 ± 0.0
5.216AspGlu: 5.216 ± 0.0
2.086AspPhe: 2.086 ± 0.0
4.868AspGly: 4.868 ± 0.0
1.739AspHis: 1.739 ± 0.0
2.086AspIle: 2.086 ± 0.0
3.825AspLys: 3.825 ± 0.0
7.65AspLeu: 7.65 ± 0.0
1.391AspMet: 1.391 ± 0.0
1.739AspAsn: 1.739 ± 0.0
3.477AspPro: 3.477 ± 0.0
1.043AspGln: 1.043 ± 0.0
3.129AspArg: 3.129 ± 0.0
4.52AspSer: 4.52 ± 0.0
3.825AspThr: 3.825 ± 0.0
3.129AspVal: 3.129 ± 0.0
1.043AspTrp: 1.043 ± 0.0
2.782AspTyr: 2.782 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
2.086GluAla: 2.086 ± 0.0
1.739GluCys: 1.739 ± 0.0
2.782GluAsp: 2.782 ± 0.0
2.434GluGlu: 2.434 ± 0.0
2.086GluPhe: 2.086 ± 0.0
3.477GluGly: 3.477 ± 0.0
2.434GluHis: 2.434 ± 0.0
3.825GluIle: 3.825 ± 0.0
2.086GluLys: 2.086 ± 0.0
3.825GluLeu: 3.825 ± 0.0
2.782GluMet: 2.782 ± 0.0
1.391GluAsn: 1.391 ± 0.0
2.434GluPro: 2.434 ± 0.0
4.868GluGln: 4.868 ± 0.0
3.129GluArg: 3.129 ± 0.0
3.129GluSer: 3.129 ± 0.0
3.825GluThr: 3.825 ± 0.0
2.434GluVal: 2.434 ± 0.0
0.695GluTrp: 0.695 ± 0.0
2.086GluTyr: 2.086 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
4.172PheAla: 4.172 ± 0.0
2.086PheCys: 2.086 ± 0.0
3.477PheAsp: 3.477 ± 0.0
2.434PheGlu: 2.434 ± 0.0
2.086PhePhe: 2.086 ± 0.0
5.563PheGly: 5.563 ± 0.0
0.348PheHis: 0.348 ± 0.0
1.739PheIle: 1.739 ± 0.0
2.086PheLys: 2.086 ± 0.0
3.825PheLeu: 3.825 ± 0.0
1.739PheMet: 1.739 ± 0.0
2.086PheAsn: 2.086 ± 0.0
2.434PhePro: 2.434 ± 0.0
1.739PheGln: 1.739 ± 0.0
4.52PheArg: 4.52 ± 0.0
4.172PheSer: 4.172 ± 0.0
1.043PheThr: 1.043 ± 0.0
2.782PheVal: 2.782 ± 0.0
0.348PheTrp: 0.348 ± 0.0
2.434PheTyr: 2.434 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
2.782GlyAla: 2.782 ± 0.0
1.391GlyCys: 1.391 ± 0.0
4.52GlyAsp: 4.52 ± 0.0
3.825GlyGlu: 3.825 ± 0.0
2.782GlyPhe: 2.782 ± 0.0
3.825GlyGly: 3.825 ± 0.0
0.695GlyHis: 0.695 ± 0.0
5.216GlyIle: 5.216 ± 0.0
2.782GlyLys: 2.782 ± 0.0
5.563GlyLeu: 5.563 ± 0.0
1.739GlyMet: 1.739 ± 0.0
3.129GlyAsn: 3.129 ± 0.0
3.129GlyPro: 3.129 ± 0.0
1.043GlyGln: 1.043 ± 0.0
2.086GlyArg: 2.086 ± 0.0
7.65GlySer: 7.65 ± 0.0
6.606GlyThr: 6.606 ± 0.0
3.825GlyVal: 3.825 ± 0.0
0.0GlyTrp: 0.0 ± 0.0
1.391GlyTyr: 1.391 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
1.043HisAla: 1.043 ± 0.0
0.348HisCys: 0.348 ± 0.0
0.695HisAsp: 0.695 ± 0.0
1.739HisGlu: 1.739 ± 0.0
1.043HisPhe: 1.043 ± 0.0
0.695HisGly: 0.695 ± 0.0
0.348HisHis: 0.348 ± 0.0
1.043HisIle: 1.043 ± 0.0
1.391HisLys: 1.391 ± 0.0
0.695HisLeu: 0.695 ± 0.0
0.0HisMet: 0.0 ± 0.0
0.695HisAsn: 0.695 ± 0.0
0.695HisPro: 0.695 ± 0.0
0.0HisGln: 0.0 ± 0.0
1.739HisArg: 1.739 ± 0.0
1.739HisSer: 1.739 ± 0.0
1.391HisThr: 1.391 ± 0.0
2.782HisVal: 2.782 ± 0.0
0.0HisTrp: 0.0 ± 0.0
1.739HisTyr: 1.739 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
5.911IleAla: 5.911 ± 0.0
0.348IleCys: 0.348 ± 0.0
5.563IleAsp: 5.563 ± 0.0
2.782IleGlu: 2.782 ± 0.0
2.434IlePhe: 2.434 ± 0.0
3.825IleGly: 3.825 ± 0.0
0.0IleHis: 0.0 ± 0.0
3.129IleIle: 3.129 ± 0.0
1.043IleLys: 1.043 ± 0.0
3.129IleLeu: 3.129 ± 0.0
1.391IleMet: 1.391 ± 0.0
3.129IleAsn: 3.129 ± 0.0
2.086IlePro: 2.086 ± 0.0
1.391IleGln: 1.391 ± 0.0
3.477IleArg: 3.477 ± 0.0
1.739IleSer: 1.739 ± 0.0
4.868IleThr: 4.868 ± 0.0
4.172IleVal: 4.172 ± 0.0
1.391IleTrp: 1.391 ± 0.0
1.391IleTyr: 1.391 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
2.086LysAla: 2.086 ± 0.0
0.348LysCys: 0.348 ± 0.0
3.825LysAsp: 3.825 ± 0.0
2.086LysGlu: 2.086 ± 0.0
3.477LysPhe: 3.477 ± 0.0
1.391LysGly: 1.391 ± 0.0
0.348LysHis: 0.348 ± 0.0
2.782LysIle: 2.782 ± 0.0
3.129LysLys: 3.129 ± 0.0
3.129LysLeu: 3.129 ± 0.0
1.739LysMet: 1.739 ± 0.0
1.739LysAsn: 1.739 ± 0.0
1.739LysPro: 1.739 ± 0.0
1.391LysGln: 1.391 ± 0.0
4.868LysArg: 4.868 ± 0.0
3.129LysSer: 3.129 ± 0.0
3.129LysThr: 3.129 ± 0.0
2.782LysVal: 2.782 ± 0.0
0.348LysTrp: 0.348 ± 0.0
0.348LysTyr: 0.348 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
8.693LeuAla: 8.693 ± 0.0
2.086LeuCys: 2.086 ± 0.0
5.563LeuAsp: 5.563 ± 0.0
5.216LeuGlu: 5.216 ± 0.0
2.086LeuPhe: 2.086 ± 0.0
3.129LeuGly: 3.129 ± 0.0
1.739LeuHis: 1.739 ± 0.0
3.825LeuIle: 3.825 ± 0.0
5.911LeuLys: 5.911 ± 0.0
6.606LeuLeu: 6.606 ± 0.0
2.086LeuMet: 2.086 ± 0.0
2.086LeuAsn: 2.086 ± 0.0
3.477LeuPro: 3.477 ± 0.0
2.086LeuGln: 2.086 ± 0.0
4.172LeuArg: 4.172 ± 0.0
4.172LeuSer: 4.172 ± 0.0
6.954LeuThr: 6.954 ± 0.0
2.782LeuVal: 2.782 ± 0.0
1.043LeuTrp: 1.043 ± 0.0
2.434LeuTyr: 2.434 ± 0.0
0.0LeuXaa: 0.0 ± 0.0
Met
2.434MetAla: 2.434 ± 0.0
1.739MetCys: 1.739 ± 0.0
1.043MetAsp: 1.043 ± 0.0
0.348MetGlu: 0.348 ± 0.0
0.695MetPhe: 0.695 ± 0.0
1.739MetGly: 1.739 ± 0.0
1.391MetHis: 1.391 ± 0.0
1.043MetIle: 1.043 ± 0.0
2.086MetLys: 2.086 ± 0.0
2.434MetLeu: 2.434 ± 0.0
1.739MetMet: 1.739 ± 0.0
1.391MetAsn: 1.391 ± 0.0
2.086MetPro: 2.086 ± 0.0
1.043MetGln: 1.043 ± 0.0
0.695MetArg: 0.695 ± 0.0
2.086MetSer: 2.086 ± 0.0
1.391MetThr: 1.391 ± 0.0
3.129MetVal: 3.129 ± 0.0
0.695MetTrp: 0.695 ± 0.0
1.391MetTyr: 1.391 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.739AsnAla: 1.739 ± 0.0
0.695AsnCys: 0.695 ± 0.0
3.129AsnAsp: 3.129 ± 0.0
2.086AsnGlu: 2.086 ± 0.0
2.434AsnPhe: 2.434 ± 0.0
3.825AsnGly: 3.825 ± 0.0
0.348AsnHis: 0.348 ± 0.0
2.086AsnIle: 2.086 ± 0.0
1.739AsnLys: 1.739 ± 0.0
2.086AsnLeu: 2.086 ± 0.0
1.043AsnMet: 1.043 ± 0.0
0.695AsnAsn: 0.695 ± 0.0
2.086AsnPro: 2.086 ± 0.0
1.739AsnGln: 1.739 ± 0.0
1.391AsnArg: 1.391 ± 0.0
2.782AsnSer: 2.782 ± 0.0
2.086AsnThr: 2.086 ± 0.0
3.825AsnVal: 3.825 ± 0.0
0.695AsnTrp: 0.695 ± 0.0
1.739AsnTyr: 1.739 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
4.172ProAla: 4.172 ± 0.0
0.695ProCys: 0.695 ± 0.0
3.825ProAsp: 3.825 ± 0.0
2.086ProGlu: 2.086 ± 0.0
3.825ProPhe: 3.825 ± 0.0
2.086ProGly: 2.086 ± 0.0
2.434ProHis: 2.434 ± 0.0
2.434ProIle: 2.434 ± 0.0
1.391ProLys: 1.391 ± 0.0
1.739ProLeu: 1.739 ± 0.0
0.695ProMet: 0.695 ± 0.0
1.391ProAsn: 1.391 ± 0.0
1.043ProPro: 1.043 ± 0.0
2.086ProGln: 2.086 ± 0.0
2.782ProArg: 2.782 ± 0.0
3.477ProSer: 3.477 ± 0.0
2.086ProThr: 2.086 ± 0.0
4.172ProVal: 4.172 ± 0.0
1.043ProTrp: 1.043 ± 0.0
2.086ProTyr: 2.086 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
2.434GlnAla: 2.434 ± 0.0
0.0GlnCys: 0.0 ± 0.0
0.695GlnAsp: 0.695 ± 0.0
1.739GlnGlu: 1.739 ± 0.0
1.739GlnPhe: 1.739 ± 0.0
1.391GlnGly: 1.391 ± 0.0
1.043GlnHis: 1.043 ± 0.0
2.086GlnIle: 2.086 ± 0.0
2.086GlnLys: 2.086 ± 0.0
3.477GlnLeu: 3.477 ± 0.0
1.391GlnMet: 1.391 ± 0.0
1.391GlnAsn: 1.391 ± 0.0
0.348GlnPro: 0.348 ± 0.0
0.695GlnGln: 0.695 ± 0.0
2.434GlnArg: 2.434 ± 0.0
4.172GlnSer: 4.172 ± 0.0
1.391GlnThr: 1.391 ± 0.0
1.739GlnVal: 1.739 ± 0.0
1.043GlnTrp: 1.043 ± 0.0
1.043GlnTyr: 1.043 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
3.129ArgAla: 3.129 ± 0.0
1.391ArgCys: 1.391 ± 0.0
4.52ArgAsp: 4.52 ± 0.0
2.434ArgGlu: 2.434 ± 0.0
5.563ArgPhe: 5.563 ± 0.0
3.825ArgGly: 3.825 ± 0.0
0.695ArgHis: 0.695 ± 0.0
2.782ArgIle: 2.782 ± 0.0
1.391ArgLys: 1.391 ± 0.0
4.172ArgLeu: 4.172 ± 0.0
2.086ArgMet: 2.086 ± 0.0
1.739ArgAsn: 1.739 ± 0.0
2.782ArgPro: 2.782 ± 0.0
1.739ArgGln: 1.739 ± 0.0
3.129ArgArg: 3.129 ± 0.0
6.259ArgSer: 6.259 ± 0.0
5.563ArgThr: 5.563 ± 0.0
5.563ArgVal: 5.563 ± 0.0
1.739ArgTrp: 1.739 ± 0.0
2.782ArgTyr: 2.782 ± 0.0
0.0ArgXaa: 0.0 ± 0.0
Ser
5.911SerAla: 5.911 ± 0.0
2.434SerCys: 2.434 ± 0.0
6.954SerAsp: 6.954 ± 0.0
3.825SerGlu: 3.825 ± 0.0
3.477SerPhe: 3.477 ± 0.0
4.52SerGly: 4.52 ± 0.0
1.043SerHis: 1.043 ± 0.0
6.259SerIle: 6.259 ± 0.0
1.739SerLys: 1.739 ± 0.0
7.997SerLeu: 7.997 ± 0.0
1.739SerMet: 1.739 ± 0.0
3.825SerAsn: 3.825 ± 0.0
3.129SerPro: 3.129 ± 0.0
1.739SerGln: 1.739 ± 0.0
4.52SerArg: 4.52 ± 0.0
2.782SerSer: 2.782 ± 0.0
3.477SerThr: 3.477 ± 0.0
4.52SerVal: 4.52 ± 0.0
0.695SerTrp: 0.695 ± 0.0
2.086SerTyr: 2.086 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
4.172ThrAla: 4.172 ± 0.0
1.043ThrCys: 1.043 ± 0.0
2.782ThrAsp: 2.782 ± 0.0
4.52ThrGlu: 4.52 ± 0.0
4.868ThrPhe: 4.868 ± 0.0
2.782ThrGly: 2.782 ± 0.0
0.695ThrHis: 0.695 ± 0.0
2.086ThrIle: 2.086 ± 0.0
2.782ThrLys: 2.782 ± 0.0
4.868ThrLeu: 4.868 ± 0.0
2.434ThrMet: 2.434 ± 0.0
2.782ThrAsn: 2.782 ± 0.0
4.868ThrPro: 4.868 ± 0.0
1.391ThrGln: 1.391 ± 0.0
5.563ThrArg: 5.563 ± 0.0
3.825ThrSer: 3.825 ± 0.0
3.477ThrThr: 3.477 ± 0.0
5.216ThrVal: 5.216 ± 0.0
1.739ThrTrp: 1.739 ± 0.0
5.216ThrTyr: 5.216 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
6.606ValAla: 6.606 ± 0.0
1.391ValCys: 1.391 ± 0.0
4.52ValAsp: 4.52 ± 0.0
2.434ValGlu: 2.434 ± 0.0
3.477ValPhe: 3.477 ± 0.0
4.172ValGly: 4.172 ± 0.0
0.348ValHis: 0.348 ± 0.0
3.129ValIle: 3.129 ± 0.0
2.782ValLys: 2.782 ± 0.0
4.52ValLeu: 4.52 ± 0.0
2.434ValMet: 2.434 ± 0.0
3.129ValAsn: 3.129 ± 0.0
3.129ValPro: 3.129 ± 0.0
1.739ValGln: 1.739 ± 0.0
5.216ValArg: 5.216 ± 0.0
6.606ValSer: 6.606 ± 0.0
5.911ValThr: 5.911 ± 0.0
4.172ValVal: 4.172 ± 0.0
1.739ValTrp: 1.739 ± 0.0
2.782ValTyr: 2.782 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
1.391TrpAla: 1.391 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.695TrpAsp: 0.695 ± 0.0
1.391TrpGlu: 1.391 ± 0.0
1.043TrpPhe: 1.043 ± 0.0
0.348TrpGly: 0.348 ± 0.0
0.348TrpHis: 0.348 ± 0.0
0.695TrpIle: 0.695 ± 0.0
1.043TrpLys: 1.043 ± 0.0
1.391TrpLeu: 1.391 ± 0.0
0.0TrpMet: 0.0 ± 0.0
0.695TrpAsn: 0.695 ± 0.0
0.348TrpPro: 0.348 ± 0.0
0.695TrpGln: 0.695 ± 0.0
2.086TrpArg: 2.086 ± 0.0
1.043TrpSer: 1.043 ± 0.0
1.043TrpThr: 1.043 ± 0.0
1.739TrpVal: 1.739 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.348TrpTyr: 0.348 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.477TyrAla: 3.477 ± 0.0
0.348TyrCys: 0.348 ± 0.0
1.391TyrAsp: 1.391 ± 0.0
2.782TyrGlu: 2.782 ± 0.0
1.043TyrPhe: 1.043 ± 0.0
4.172TyrGly: 4.172 ± 0.0
1.043TyrHis: 1.043 ± 0.0
1.739TyrIle: 1.739 ± 0.0
1.739TyrLys: 1.739 ± 0.0
4.172TyrLeu: 4.172 ± 0.0
1.391TyrMet: 1.391 ± 0.0
1.043TyrAsn: 1.043 ± 0.0
0.348TyrPro: 0.348 ± 0.0
1.391TyrGln: 1.391 ± 0.0
4.172TyrArg: 4.172 ± 0.0
2.782TyrSer: 2.782 ± 0.0
1.739TyrThr: 1.739 ± 0.0
2.086TyrVal: 2.086 ± 0.0
1.391TyrTrp: 1.391 ± 0.0
1.043TyrTyr: 1.043 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1 proteins (2877 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski