Amino acid dipepetide frequency for Sphingomonas palmae

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	21.771AlaAla: 21.771 ± 0.221	1.128AlaCys: 1.128 ± 0.043	8.164AlaAsp: 8.164 ± 0.113	7.481AlaGlu: 7.481 ± 0.117	4.511AlaPhe: 4.511 ± 0.075	12.563AlaGly: 12.563 ± 0.143	2.569AlaHis: 2.569 ± 0.053	6.872AlaIle: 6.872 ± 0.09	3.849AlaLys: 3.849 ± 0.069	14.805AlaLeu: 14.805 ± 0.173	3.878AlaMet: 3.878 ± 0.07	3.291AlaAsn: 3.291 ± 0.061	6.929AlaPro: 6.929 ± 0.101	4.792AlaGln: 4.792 ± 0.082	11.436AlaArg: 11.436 ± 0.146	6.856AlaSer: 6.856 ± 0.091	7.7AlaThr: 7.7 ± 0.082	9.503AlaVal: 9.503 ± 0.105	1.804AlaTrp: 1.804 ± 0.051	2.58AlaTyr: 2.58 ± 0.057	0.0AlaXaa: 0.0 ± 0.0
Cys	1.018CysAla: 1.018 ± 0.033	0.081CysCys: 0.081 ± 0.011	0.489CysAsp: 0.489 ± 0.025	0.341CysGlu: 0.341 ± 0.019	0.254CysPhe: 0.254 ± 0.018	0.804CysGly: 0.804 ± 0.03	0.173CysHis: 0.173 ± 0.013	0.276CysIle: 0.276 ± 0.018	0.116CysLys: 0.116 ± 0.012	0.6CysLeu: 0.6 ± 0.028	0.125CysMet: 0.125 ± 0.011	0.182CysAsn: 0.182 ± 0.012	0.379CysPro: 0.379 ± 0.021	0.153CysGln: 0.153 ± 0.011	0.555CysArg: 0.555 ± 0.023	0.386CysSer: 0.386 ± 0.019	0.412CysThr: 0.412 ± 0.021	0.585CysVal: 0.585 ± 0.026	0.102CysTrp: 0.102 ± 0.01	0.148CysTyr: 0.148 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	9.201AspAla: 9.201 ± 0.11	0.415AspCys: 0.415 ± 0.022	3.706AspAsp: 3.706 ± 0.082	3.474AspGlu: 3.474 ± 0.066	1.947AspPhe: 1.947 ± 0.046	5.434AspGly: 5.434 ± 0.091	1.399AspHis: 1.399 ± 0.041	2.263AspIle: 2.263 ± 0.048	1.569AspLys: 1.569 ± 0.043	5.864AspLeu: 5.864 ± 0.079	1.288AspMet: 1.288 ± 0.038	1.237AspAsn: 1.237 ± 0.042	3.633AspPro: 3.633 ± 0.062	1.96AspGln: 1.96 ± 0.045	5.179AspArg: 5.179 ± 0.081	1.832AspSer: 1.832 ± 0.049	3.064AspThr: 3.064 ± 0.061	4.503AspVal: 4.503 ± 0.062	1.151AspTrp: 1.151 ± 0.034	1.686AspTyr: 1.686 ± 0.042	0.0AspXaa: 0.0 ± 0.0
Glu	7.564GluAla: 7.564 ± 0.119	0.281GluCys: 0.281 ± 0.016	2.51GluAsp: 2.51 ± 0.058	2.636GluGlu: 2.636 ± 0.066	1.218GluPhe: 1.218 ± 0.037	4.016GluGly: 4.016 ± 0.071	1.207GluHis: 1.207 ± 0.039	2.469GluIle: 2.469 ± 0.055	1.505GluLys: 1.505 ± 0.043	4.704GluLeu: 4.704 ± 0.076	1.198GluMet: 1.198 ± 0.034	1.15GluAsn: 1.15 ± 0.038	2.506GluPro: 2.506 ± 0.057	2.271GluGln: 2.271 ± 0.054	5.407GluArg: 5.407 ± 0.096	1.718GluSer: 1.718 ± 0.043	2.795GluThr: 2.795 ± 0.057	3.793GluVal: 3.793 ± 0.071	0.738GluTrp: 0.738 ± 0.027	0.863GluTyr: 0.863 ± 0.032	0.0GluXaa: 0.0 ± 0.0
Phe	4.985PheAla: 4.985 ± 0.067	0.29PheCys: 0.29 ± 0.016	2.629PheAsp: 2.629 ± 0.055	1.753PheGlu: 1.753 ± 0.047	1.156PhePhe: 1.156 ± 0.039	3.439PheGly: 3.439 ± 0.07	0.665PheHis: 0.665 ± 0.026	1.187PheIle: 1.187 ± 0.04	0.755PheLys: 0.755 ± 0.03	2.873PheLeu: 2.873 ± 0.063	0.651PheMet: 0.651 ± 0.025	0.935PheAsn: 0.935 ± 0.033	1.375PhePro: 1.375 ± 0.034	0.785PheGln: 0.785 ± 0.025	2.119PheArg: 2.119 ± 0.042	1.689PheSer: 1.689 ± 0.041	2.072PheThr: 2.072 ± 0.053	2.709PheVal: 2.709 ± 0.06	0.473PheTrp: 0.473 ± 0.025	0.862PheTyr: 0.862 ± 0.033	0.0PheXaa: 0.0 ± 0.0
Gly	10.886GlyAla: 10.886 ± 0.125	0.786GlyCys: 0.786 ± 0.032	5.199GlyAsp: 5.199 ± 0.077	4.775GlyGlu: 4.775 ± 0.071	3.363GlyPhe: 3.363 ± 0.063	8.221GlyGly: 8.221 ± 0.15	1.835GlyHis: 1.835 ± 0.05	4.026GlyIle: 4.026 ± 0.078	2.789GlyLys: 2.789 ± 0.061	8.042GlyLeu: 8.042 ± 0.107	2.214GlyMet: 2.214 ± 0.053	2.214GlyAsn: 2.214 ± 0.051	3.257GlyPro: 3.257 ± 0.062	2.966GlyGln: 2.966 ± 0.067	6.774GlyArg: 6.774 ± 0.081	4.718GlySer: 4.718 ± 0.083	5.13GlyThr: 5.13 ± 0.087	7.106GlyVal: 7.106 ± 0.097	1.688GlyTrp: 1.688 ± 0.048	2.402GlyTyr: 2.402 ± 0.05	0.0GlyXaa: 0.0 ± 0.0
His	2.862HisAla: 2.862 ± 0.071	0.178HisCys: 0.178 ± 0.012	1.365HisAsp: 1.365 ± 0.037	0.948HisGlu: 0.948 ± 0.032	0.718HisPhe: 0.718 ± 0.028	1.927HisGly: 1.927 ± 0.048	0.587HisHis: 0.587 ± 0.03	0.712HisIle: 0.712 ± 0.029	0.363HisLys: 0.363 ± 0.019	1.925HisLeu: 1.925 ± 0.044	0.38HisMet: 0.38 ± 0.019	0.444HisAsn: 0.444 ± 0.021	1.302HisPro: 1.302 ± 0.038	0.542HisGln: 0.542 ± 0.026	1.52HisArg: 1.52 ± 0.04	0.768HisSer: 0.768 ± 0.029	0.707HisThr: 0.707 ± 0.027	1.583HisVal: 1.583 ± 0.042	0.348HisTrp: 0.348 ± 0.017	0.511HisTyr: 0.511 ± 0.024	0.0HisXaa: 0.0 ± 0.0
Ile	7.778IleAla: 7.778 ± 0.094	0.341IleCys: 0.341 ± 0.018	3.87IleAsp: 3.87 ± 0.062	3.142IleGlu: 3.142 ± 0.061	1.23IlePhe: 1.23 ± 0.04	4.798IleGly: 4.798 ± 0.077	0.81IleHis: 0.81 ± 0.029	1.603IleIle: 1.603 ± 0.045	1.116IleLys: 1.116 ± 0.038	3.304IleLeu: 3.304 ± 0.057	0.693IleMet: 0.693 ± 0.032	1.239IleAsn: 1.239 ± 0.046	1.902IlePro: 1.902 ± 0.045	1.033IleGln: 1.033 ± 0.03	2.925IleArg: 2.925 ± 0.06	1.993IleSer: 1.993 ± 0.049	2.479IleThr: 2.479 ± 0.054	4.13IleVal: 4.13 ± 0.071	0.492IleTrp: 0.492 ± 0.025	0.889IleTyr: 0.889 ± 0.035	0.0IleXaa: 0.0 ± 0.0
Lys	3.448LysAla: 3.448 ± 0.062	0.12LysCys: 0.12 ± 0.011	1.305LysAsp: 1.305 ± 0.039	1.019LysGlu: 1.019 ± 0.038	0.693LysPhe: 0.693 ± 0.028	2.193LysGly: 2.193 ± 0.053	0.461LysHis: 0.461 ± 0.022	1.13LysIle: 1.13 ± 0.035	0.975LysLys: 0.975 ± 0.039	2.81LysLeu: 2.81 ± 0.058	0.634LysMet: 0.634 ± 0.026	0.658LysAsn: 0.658 ± 0.03	1.895LysPro: 1.895 ± 0.05	0.884LysGln: 0.884 ± 0.032	2.182LysArg: 2.182 ± 0.049	1.353LysSer: 1.353 ± 0.04	1.517LysThr: 1.517 ± 0.045	1.999LysVal: 1.999 ± 0.055	0.349LysTrp: 0.349 ± 0.022	0.497LysTyr: 0.497 ± 0.019	0.0LysXaa: 0.0 ± 0.0
Leu	14.436LeuAla: 14.436 ± 0.142	0.688LeuCys: 0.688 ± 0.03	6.258LeuAsp: 6.258 ± 0.084	4.219LeuGlu: 4.219 ± 0.081	3.524LeuPhe: 3.524 ± 0.065	8.321LeuGly: 8.321 ± 0.096	1.82LeuHis: 1.82 ± 0.04	4.503LeuIle: 4.503 ± 0.074	2.548LeuLys: 2.548 ± 0.058	9.735LeuLeu: 9.735 ± 0.119	1.986LeuMet: 1.986 ± 0.046	2.348LeuAsn: 2.348 ± 0.053	5.761LeuPro: 5.761 ± 0.08	2.29LeuGln: 2.29 ± 0.051	7.073LeuArg: 7.073 ± 0.088	6.069LeuSer: 6.069 ± 0.082	5.702LeuThr: 5.702 ± 0.072	7.712LeuVal: 7.712 ± 0.117	1.178LeuTrp: 1.178 ± 0.038	1.847LeuTyr: 1.847 ± 0.039	0.0LeuXaa: 0.0 ± 0.0
Met	2.929MetAla: 2.929 ± 0.055	0.151MetCys: 0.151 ± 0.012	0.939MetAsp: 0.939 ± 0.032	0.88MetGlu: 0.88 ± 0.032	0.639MetPhe: 0.639 ± 0.026	1.627MetGly: 1.627 ± 0.045	0.395MetHis: 0.395 ± 0.02	1.263MetIle: 1.263 ± 0.036	0.814MetLys: 0.814 ± 0.033	2.534MetLeu: 2.534 ± 0.055	0.584MetMet: 0.584 ± 0.03	0.702MetAsn: 0.702 ± 0.03	1.362MetPro: 1.362 ± 0.034	0.73MetGln: 0.73 ± 0.031	1.822MetArg: 1.822 ± 0.052	1.424MetSer: 1.424 ± 0.033	1.841MetThr: 1.841 ± 0.042	1.521MetVal: 1.521 ± 0.038	0.206MetTrp: 0.206 ± 0.015	0.257MetTyr: 0.257 ± 0.016	0.0MetXaa: 0.0 ± 0.0
Asn	3.348AsnAla: 3.348 ± 0.067	0.206AsnCys: 0.206 ± 0.016	1.42AsnAsp: 1.42 ± 0.042	1.101AsnGlu: 1.101 ± 0.037	0.844AsnPhe: 0.844 ± 0.036	2.432AsnGly: 2.432 ± 0.065	0.427AsnHis: 0.427 ± 0.024	1.087AsnIle: 1.087 ± 0.038	0.615AsnLys: 0.615 ± 0.026	2.364AsnLeu: 2.364 ± 0.05	0.467AsnMet: 0.467 ± 0.023	0.681AsnAsn: 0.681 ± 0.036	1.608AsnPro: 1.608 ± 0.048	0.716AsnGln: 0.716 ± 0.032	1.794AsnArg: 1.794 ± 0.042	1.086AsnSer: 1.086 ± 0.043	1.286AsnThr: 1.286 ± 0.044	1.921AsnVal: 1.921 ± 0.053	0.377AsnTrp: 0.377 ± 0.019	0.641AsnTyr: 0.641 ± 0.028	0.0AsnXaa: 0.0 ± 0.0
Pro	7.763ProAla: 7.763 ± 0.1	0.286ProCys: 0.286 ± 0.018	3.669ProAsp: 3.669 ± 0.061	3.159ProGlu: 3.159 ± 0.058	1.868ProPhe: 1.868 ± 0.05	4.682ProGly: 4.682 ± 0.071	1.013ProHis: 1.013 ± 0.032	2.41ProIle: 2.41 ± 0.038	1.391ProLys: 1.391 ± 0.037	4.959ProLeu: 4.959 ± 0.079	1.122ProMet: 1.122 ± 0.033	1.27ProAsn: 1.27 ± 0.036	2.75ProPro: 2.75 ± 0.074	1.584ProGln: 1.584 ± 0.038	3.389ProArg: 3.389 ± 0.063	2.636ProSer: 2.636 ± 0.057	2.925ProThr: 2.925 ± 0.06	4.386ProVal: 4.386 ± 0.067	0.669ProTrp: 0.669 ± 0.024	1.055ProTyr: 1.055 ± 0.038	0.0ProXaa: 0.0 ± 0.0
Gln	4.447GlnAla: 4.447 ± 0.074	0.189GlnCys: 0.189 ± 0.014	1.254GlnAsp: 1.254 ± 0.035	1.182GlnGlu: 1.182 ± 0.033	0.945GlnPhe: 0.945 ± 0.035	2.391GlnGly: 2.391 ± 0.053	0.62GlnHis: 0.62 ± 0.025	1.527GlnIle: 1.527 ± 0.038	0.739GlnLys: 0.739 ± 0.031	3.182GlnLeu: 3.182 ± 0.059	0.789GlnMet: 0.789 ± 0.027	0.702GlnAsn: 0.702 ± 0.03	1.874GlnPro: 1.874 ± 0.044	1.3GlnGln: 1.3 ± 0.043	2.811GlnArg: 2.811 ± 0.054	1.604GlnSer: 1.604 ± 0.048	1.664GlnThr: 1.664 ± 0.046	2.728GlnVal: 2.728 ± 0.052	0.402GlnTrp: 0.402 ± 0.019	0.577GlnTyr: 0.577 ± 0.028	0.0GlnXaa: 0.0 ± 0.0
Arg	10.693ArgAla: 10.693 ± 0.129	0.507ArgCys: 0.507 ± 0.025	4.937ArgAsp: 4.937 ± 0.083	4.036ArgGlu: 4.036 ± 0.07	3.161ArgPhe: 3.161 ± 0.065	5.754ArgGly: 5.754 ± 0.08	1.711ArgHis: 1.711 ± 0.049	3.777ArgIle: 3.777 ± 0.063	1.625ArgLys: 1.625 ± 0.046	8.357ArgLeu: 8.357 ± 0.12	2.057ArgMet: 2.057 ± 0.038	1.68ArgAsn: 1.68 ± 0.047	3.768ArgPro: 3.768 ± 0.061	2.439ArgGln: 2.439 ± 0.05	6.52ArgArg: 6.52 ± 0.087	3.711ArgSer: 3.711 ± 0.059	3.802ArgThr: 3.802 ± 0.064	6.306ArgVal: 6.306 ± 0.101	1.322ArgTrp: 1.322 ± 0.039	2.01ArgTyr: 2.01 ± 0.044	0.0ArgXaa: 0.0 ± 0.0
Ser	6.6SerAla: 6.6 ± 0.088	0.346SerCys: 0.346 ± 0.02	3.106SerAsp: 3.106 ± 0.055	2.26SerGlu: 2.26 ± 0.051	1.923SerPhe: 1.923 ± 0.045	5.264SerGly: 5.264 ± 0.085	0.858SerHis: 0.858 ± 0.033	2.427SerIle: 2.427 ± 0.054	1.233SerLys: 1.233 ± 0.037	4.715SerLeu: 4.715 ± 0.078	1.018SerMet: 1.018 ± 0.034	1.37SerAsn: 1.37 ± 0.045	2.798SerPro: 2.798 ± 0.057	1.31SerGln: 1.31 ± 0.035	3.361SerArg: 3.361 ± 0.056	2.664SerSer: 2.664 ± 0.063	2.756SerThr: 2.756 ± 0.058	3.799SerVal: 3.799 ± 0.065	0.686SerTrp: 0.686 ± 0.026	1.272SerTyr: 1.272 ± 0.036	0.0SerXaa: 0.0 ± 0.0
Thr	7.043ThrAla: 7.043 ± 0.087	0.382ThrCys: 0.382 ± 0.021	3.04ThrAsp: 3.04 ± 0.062	2.111ThrGlu: 2.111 ± 0.049	1.942ThrPhe: 1.942 ± 0.051	5.513ThrGly: 5.513 ± 0.09	0.99ThrHis: 0.99 ± 0.031	3.129ThrIle: 3.129 ± 0.054	1.362ThrLys: 1.362 ± 0.042	6.319ThrLeu: 6.319 ± 0.083	1.17ThrMet: 1.17 ± 0.033	1.346ThrAsn: 1.346 ± 0.038	3.868ThrPro: 3.868 ± 0.077	1.708ThrGln: 1.708 ± 0.049	4.241ThrArg: 4.241 ± 0.066	2.796ThrSer: 2.796 ± 0.061	3.094ThrThr: 3.094 ± 0.074	4.122ThrVal: 4.122 ± 0.067	0.723ThrTrp: 0.723 ± 0.026	1.133ThrTyr: 1.133 ± 0.04	0.0ThrXaa: 0.0 ± 0.0
Val	11.536ValAla: 11.536 ± 0.128	0.502ValCys: 0.502 ± 0.023	4.689ValAsp: 4.689 ± 0.071	4.474ValGlu: 4.474 ± 0.084	2.151ValPhe: 2.151 ± 0.05	5.969ValGly: 5.969 ± 0.091	1.325ValHis: 1.325 ± 0.042	3.765ValIle: 3.765 ± 0.069	1.864ValLys: 1.864 ± 0.05	7.17ValLeu: 7.17 ± 0.1	1.652ValMet: 1.652 ± 0.041	1.927ValAsn: 1.927 ± 0.05	4.245ValPro: 4.245 ± 0.073	2.114ValGln: 2.114 ± 0.051	5.712ValArg: 5.712 ± 0.072	4.403ValSer: 4.403 ± 0.079	5.168ValThr: 5.168 ± 0.074	6.154ValVal: 6.154 ± 0.103	0.897ValTrp: 0.897 ± 0.029	1.305ValTyr: 1.305 ± 0.037	0.0ValXaa: 0.0 ± 0.0
Trp	1.35TrpAla: 1.35 ± 0.038	0.125TrpCys: 0.125 ± 0.013	0.667TrpAsp: 0.667 ± 0.028	0.53TrpGlu: 0.53 ± 0.024	0.557TrpPhe: 0.557 ± 0.025	0.968TrpGly: 0.968 ± 0.032	0.359TrpHis: 0.359 ± 0.017	0.649TrpIle: 0.649 ± 0.027	0.394TrpLys: 0.394 ± 0.021	1.69TrpLeu: 1.69 ± 0.046	0.356TrpMet: 0.356 ± 0.019	0.457TrpAsn: 0.457 ± 0.023	0.738TrpPro: 0.738 ± 0.026	0.66TrpGln: 0.66 ± 0.029	1.459TrpArg: 1.459 ± 0.041	0.948TrpSer: 0.948 ± 0.03	0.864TrpThr: 0.864 ± 0.028	0.874TrpVal: 0.874 ± 0.031	0.315TrpTrp: 0.315 ± 0.019	0.299TrpTyr: 0.299 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.824TyrAla: 2.824 ± 0.055	0.179TyrCys: 0.179 ± 0.015	1.59TyrAsp: 1.59 ± 0.044	1.026TyrGlu: 1.026 ± 0.034	0.753TyrPhe: 0.753 ± 0.031	2.075TyrGly: 2.075 ± 0.055	0.469TyrHis: 0.469 ± 0.02	0.693TyrIle: 0.693 ± 0.027	0.496TyrLys: 0.496 ± 0.027	2.066TyrLeu: 2.066 ± 0.05	0.358TyrMet: 0.358 ± 0.02	0.591TyrAsn: 0.591 ± 0.024	1.036TyrPro: 1.036 ± 0.027	0.69TyrGln: 0.69 ± 0.028	1.894TyrArg: 1.894 ± 0.05	1.111TyrSer: 1.111 ± 0.036	1.053TyrThr: 1.053 ± 0.036	1.588TyrVal: 1.588 ± 0.043	0.339TyrTrp: 0.339 ± 0.018	0.56TyrTyr: 0.56 ± 0.026	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3122 proteins (994220 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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