Amino acid dipepetide frequency for Mariniblastus fucicola

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.216AlaAla: 9.216 ± 0.099	1.005AlaCys: 1.005 ± 0.026	5.853AlaAsp: 5.853 ± 0.073	6.039AlaGlu: 6.039 ± 0.076	3.495AlaPhe: 3.495 ± 0.048	6.592AlaGly: 6.592 ± 0.087	1.37AlaHis: 1.37 ± 0.028	6.046AlaIle: 6.046 ± 0.066	4.563AlaLys: 4.563 ± 0.058	6.87AlaLeu: 6.87 ± 0.073	2.556AlaMet: 2.556 ± 0.038	3.782AlaAsn: 3.782 ± 0.062	3.105AlaPro: 3.105 ± 0.05	3.038AlaGln: 3.038 ± 0.044	4.422AlaArg: 4.422 ± 0.052	6.155AlaSer: 6.155 ± 0.058	5.412AlaThr: 5.412 ± 0.088	6.083AlaVal: 6.083 ± 0.078	1.301AlaTrp: 1.301 ± 0.03	1.741AlaTyr: 1.741 ± 0.033	0.0AlaXaa: 0.0 ± 0.0
Cys	0.792CysAla: 0.792 ± 0.023	0.249CysCys: 0.249 ± 0.012	0.752CysAsp: 0.752 ± 0.024	0.759CysGlu: 0.759 ± 0.023	0.536CysPhe: 0.536 ± 0.015	1.01CysGly: 1.01 ± 0.034	0.35CysHis: 0.35 ± 0.016	0.519CysIle: 0.519 ± 0.015	0.413CysLys: 0.413 ± 0.017	1.069CysLeu: 1.069 ± 0.025	0.244CysMet: 0.244 ± 0.013	0.385CysAsn: 0.385 ± 0.015	0.536CysPro: 0.536 ± 0.017	0.397CysGln: 0.397 ± 0.013	0.717CysArg: 0.717 ± 0.021	0.77CysSer: 0.77 ± 0.022	0.457CysThr: 0.457 ± 0.015	0.811CysVal: 0.811 ± 0.021	0.155CysTrp: 0.155 ± 0.01	0.296CysTyr: 0.296 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	5.905AspAla: 5.905 ± 0.092	0.66AspCys: 0.66 ± 0.019	4.474AspAsp: 4.474 ± 0.075	4.508AspGlu: 4.508 ± 0.056	2.982AspPhe: 2.982 ± 0.049	5.839AspGly: 5.839 ± 0.126	1.342AspHis: 1.342 ± 0.03	2.886AspIle: 2.886 ± 0.048	2.212AspLys: 2.212 ± 0.04	5.613AspLeu: 5.613 ± 0.062	1.148AspMet: 1.148 ± 0.028	2.037AspAsn: 2.037 ± 0.048	3.294AspPro: 3.294 ± 0.061	2.539AspGln: 2.539 ± 0.038	4.049AspArg: 4.049 ± 0.057	4.907AspSer: 4.907 ± 0.078	2.641AspThr: 2.641 ± 0.056	4.496AspVal: 4.496 ± 0.056	1.045AspTrp: 1.045 ± 0.024	1.68AspTyr: 1.68 ± 0.045	0.0AspXaa: 0.0 ± 0.0
Glu	5.362GluAla: 5.362 ± 0.077	0.529GluCys: 0.529 ± 0.02	3.451GluAsp: 3.451 ± 0.05	3.832GluGlu: 3.832 ± 0.07	2.901GluPhe: 2.901 ± 0.049	3.792GluGly: 3.792 ± 0.06	1.271GluHis: 1.271 ± 0.031	4.145GluIle: 4.145 ± 0.053	3.602GluLys: 3.602 ± 0.06	6.905GluLeu: 6.905 ± 0.067	1.732GluMet: 1.732 ± 0.027	2.837GluAsn: 2.837 ± 0.05	2.726GluPro: 2.726 ± 0.048	2.885GluGln: 2.885 ± 0.049	3.373GluArg: 3.373 ± 0.05	5.521GluSer: 5.521 ± 0.065	4.116GluThr: 4.116 ± 0.052	4.497GluVal: 4.497 ± 0.056	0.63GluTrp: 0.63 ± 0.019	1.452GluTyr: 1.452 ± 0.031	0.0GluXaa: 0.0 ± 0.0
Phe	4.145PheAla: 4.145 ± 0.053	0.613PheCys: 0.613 ± 0.02	3.336PheAsp: 3.336 ± 0.051	3.194PheGlu: 3.194 ± 0.053	1.758PhePhe: 1.758 ± 0.038	3.69PheGly: 3.69 ± 0.047	0.811PheHis: 0.811 ± 0.021	1.704PheIle: 1.704 ± 0.029	1.462PheLys: 1.462 ± 0.031	3.753PheLeu: 3.753 ± 0.054	0.787PheMet: 0.787 ± 0.022	1.577PheAsn: 1.577 ± 0.035	1.652PhePro: 1.652 ± 0.033	1.485PheGln: 1.485 ± 0.025	2.528PheArg: 2.528 ± 0.039	3.071PheSer: 3.071 ± 0.044	2.15PheThr: 2.15 ± 0.052	3.236PheVal: 3.236 ± 0.04	0.63PheTrp: 0.63 ± 0.022	1.039PheTyr: 1.039 ± 0.027	0.0PheXaa: 0.0 ± 0.0
Gly	5.356GlyAla: 5.356 ± 0.08	1.018GlyCys: 1.018 ± 0.032	5.091GlyAsp: 5.091 ± 0.093	4.571GlyGlu: 4.571 ± 0.056	3.351GlyPhe: 3.351 ± 0.049	6.19GlyGly: 6.19 ± 0.122	1.498GlyHis: 1.498 ± 0.037	4.241GlyIle: 4.241 ± 0.048	4.118GlyLys: 4.118 ± 0.063	6.477GlyLeu: 6.477 ± 0.072	1.997GlyMet: 1.997 ± 0.039	3.154GlyAsn: 3.154 ± 0.06	2.529GlyPro: 2.529 ± 0.039	2.953GlyGln: 2.953 ± 0.058	3.991GlyArg: 3.991 ± 0.059	5.478GlySer: 5.478 ± 0.109	4.434GlyThr: 4.434 ± 0.103	5.175GlyVal: 5.175 ± 0.066	1.147GlyTrp: 1.147 ± 0.026	2.069GlyTyr: 2.069 ± 0.039	0.0GlyXaa: 0.0 ± 0.0
His	1.606HisAla: 1.606 ± 0.039	0.307HisCys: 0.307 ± 0.011	1.23HisAsp: 1.23 ± 0.027	1.281HisGlu: 1.281 ± 0.028	0.981HisPhe: 0.981 ± 0.023	1.537HisGly: 1.537 ± 0.033	0.574HisHis: 0.574 ± 0.019	0.875HisIle: 0.875 ± 0.023	0.619HisLys: 0.619 ± 0.022	1.846HisLeu: 1.846 ± 0.036	0.37HisMet: 0.37 ± 0.014	0.659HisAsn: 0.659 ± 0.021	1.162HisPro: 1.162 ± 0.028	0.789HisGln: 0.789 ± 0.021	1.39HisArg: 1.39 ± 0.03	1.268HisSer: 1.268 ± 0.028	0.804HisThr: 0.804 ± 0.023	1.425HisVal: 1.425 ± 0.032	0.363HisTrp: 0.363 ± 0.014	0.544HisTyr: 0.544 ± 0.016	0.0HisXaa: 0.0 ± 0.0
Ile	5.885IleAla: 5.885 ± 0.067	0.733IleCys: 0.733 ± 0.02	4.321IleAsp: 4.321 ± 0.05	4.642IleGlu: 4.642 ± 0.05	1.932IlePhe: 1.932 ± 0.032	4.689IleGly: 4.689 ± 0.053	1.069IleHis: 1.069 ± 0.023	2.165IleIle: 2.165 ± 0.036	2.165IleLys: 2.165 ± 0.047	4.449IleLeu: 4.449 ± 0.053	0.825IleMet: 0.825 ± 0.022	1.976IleAsn: 1.976 ± 0.038	2.504IlePro: 2.504 ± 0.036	1.898IleGln: 1.898 ± 0.033	3.365IleArg: 3.365 ± 0.047	3.719IleSer: 3.719 ± 0.05	2.62IleThr: 2.62 ± 0.05	4.508IleVal: 4.508 ± 0.054	0.685IleTrp: 0.685 ± 0.021	1.3IleTyr: 1.3 ± 0.025	0.0IleXaa: 0.0 ± 0.0
Lys	3.736LysAla: 3.736 ± 0.057	0.401LysCys: 0.401 ± 0.014	2.27LysAsp: 2.27 ± 0.048	2.628LysGlu: 2.628 ± 0.053	1.899LysPhe: 1.899 ± 0.033	2.452LysGly: 2.452 ± 0.046	0.973LysHis: 0.973 ± 0.024	2.628LysIle: 2.628 ± 0.041	2.807LysLys: 2.807 ± 0.083	4.794LysLeu: 4.794 ± 0.065	1.241LysMet: 1.241 ± 0.03	1.591LysAsn: 1.591 ± 0.035	2.548LysPro: 2.548 ± 0.051	2.003LysGln: 2.003 ± 0.035	2.885LysArg: 2.885 ± 0.045	3.347LysSer: 3.347 ± 0.055	2.759LysThr: 2.759 ± 0.051	3.084LysVal: 3.084 ± 0.048	0.648LysTrp: 0.648 ± 0.019	1.077LysTyr: 1.077 ± 0.028	0.0LysXaa: 0.0 ± 0.0
Leu	9.107LeuAla: 9.107 ± 0.088	1.033LeuCys: 1.033 ± 0.026	5.776LeuAsp: 5.776 ± 0.066	5.93LeuGlu: 5.93 ± 0.071	3.688LeuPhe: 3.688 ± 0.049	6.56LeuGly: 6.56 ± 0.074	1.662LeuHis: 1.662 ± 0.033	5.12LeuIle: 5.12 ± 0.058	4.535LeuLys: 4.535 ± 0.064	8.885LeuLeu: 8.885 ± 0.103	2.155LeuMet: 2.155 ± 0.038	3.452LeuAsn: 3.452 ± 0.047	4.462LeuPro: 4.462 ± 0.055	3.35LeuGln: 3.35 ± 0.046	5.119LeuArg: 5.119 ± 0.066	6.458LeuSer: 6.458 ± 0.066	5.124LeuThr: 5.124 ± 0.06	6.543LeuVal: 6.543 ± 0.067	0.978LeuTrp: 0.978 ± 0.027	1.952LeuTyr: 1.952 ± 0.032	0.0LeuXaa: 0.0 ± 0.0
Met	2.188MetAla: 2.188 ± 0.036	0.209MetCys: 0.209 ± 0.01	1.117MetAsp: 1.117 ± 0.025	1.237MetGlu: 1.237 ± 0.029	0.919MetPhe: 0.919 ± 0.02	1.486MetGly: 1.486 ± 0.04	0.461MetHis: 0.461 ± 0.018	1.391MetIle: 1.391 ± 0.033	1.345MetLys: 1.345 ± 0.028	2.545MetLeu: 2.545 ± 0.042	0.662MetMet: 0.662 ± 0.018	1.002MetAsn: 1.002 ± 0.022	1.272MetPro: 1.272 ± 0.025	1.004MetGln: 1.004 ± 0.022	1.272MetArg: 1.272 ± 0.028	1.726MetSer: 1.726 ± 0.03	1.463MetThr: 1.463 ± 0.03	1.613MetVal: 1.613 ± 0.032	0.246MetTrp: 0.246 ± 0.011	0.453MetTyr: 0.453 ± 0.014	0.0MetXaa: 0.0 ± 0.0
Asn	3.332AsnAla: 3.332 ± 0.053	0.436AsnCys: 0.436 ± 0.014	2.488AsnAsp: 2.488 ± 0.054	2.515AsnGlu: 2.515 ± 0.033	1.634AsnPhe: 1.634 ± 0.036	3.312AsnGly: 3.312 ± 0.069	0.814AsnHis: 0.814 ± 0.023	1.722AsnIle: 1.722 ± 0.034	1.18AsnLys: 1.18 ± 0.025	3.446AsnLeu: 3.446 ± 0.045	0.785AsnMet: 0.785 ± 0.019	1.318AsnAsn: 1.318 ± 0.037	2.174AsnPro: 2.174 ± 0.043	1.623AsnGln: 1.623 ± 0.034	2.644AsnArg: 2.644 ± 0.04	2.745AsnSer: 2.745 ± 0.045	1.701AsnThr: 1.701 ± 0.039	2.94AsnVal: 2.94 ± 0.047	0.65AsnTrp: 0.65 ± 0.02	1.011AsnTyr: 1.011 ± 0.025	0.0AsnXaa: 0.0 ± 0.0
Pro	4.057ProAla: 4.057 ± 0.053	0.338ProCys: 0.338 ± 0.014	3.239ProAsp: 3.239 ± 0.04	3.696ProGlu: 3.696 ± 0.057	1.842ProPhe: 1.842 ± 0.036	3.423ProGly: 3.423 ± 0.044	0.861ProHis: 0.861 ± 0.023	2.524ProIle: 2.524 ± 0.038	2.092ProLys: 2.092 ± 0.045	3.58ProLeu: 3.58 ± 0.045	1.03ProMet: 1.03 ± 0.027	1.946ProAsn: 1.946 ± 0.03	1.918ProPro: 1.918 ± 0.045	1.654ProGln: 1.654 ± 0.034	2.052ProArg: 2.052 ± 0.037	2.855ProSer: 2.855 ± 0.04	2.81ProThr: 2.81 ± 0.047	3.699ProVal: 3.699 ± 0.059	0.642ProTrp: 0.642 ± 0.019	1.011ProTyr: 1.011 ± 0.024	0.0ProXaa: 0.0 ± 0.0
Gln	3.146GlnAla: 3.146 ± 0.045	0.378GlnCys: 0.378 ± 0.013	1.726GlnAsp: 1.726 ± 0.031	1.958GlnGlu: 1.958 ± 0.034	1.788GlnPhe: 1.788 ± 0.034	2.063GlnGly: 2.063 ± 0.056	0.823GlnHis: 0.823 ± 0.022	2.491GlnIle: 2.491 ± 0.032	1.879GlnLys: 1.879 ± 0.037	4.207GlnLeu: 4.207 ± 0.058	1.037GlnMet: 1.037 ± 0.024	1.534GlnAsn: 1.534 ± 0.03	2.018GlnPro: 2.018 ± 0.041	2.205GlnGln: 2.205 ± 0.046	2.57GlnArg: 2.57 ± 0.045	2.852GlnSer: 2.852 ± 0.041	2.426GlnThr: 2.426 ± 0.046	2.415GlnVal: 2.415 ± 0.039	0.654GlnTrp: 0.654 ± 0.018	0.956GlnTyr: 0.956 ± 0.025	0.0GlnXaa: 0.0 ± 0.0
Arg	3.926ArgAla: 3.926 ± 0.055	0.606ArgCys: 0.606 ± 0.018	3.396ArgAsp: 3.396 ± 0.049	3.75ArgGlu: 3.75 ± 0.061	2.832ArgPhe: 2.832 ± 0.044	3.622ArgGly: 3.622 ± 0.058	1.202ArgHis: 1.202 ± 0.028	3.65ArgIle: 3.65 ± 0.048	3.153ArgLys: 3.153 ± 0.05	5.732ArgLeu: 5.732 ± 0.074	1.652ArgMet: 1.652 ± 0.035	2.451ArgAsn: 2.451 ± 0.038	2.328ArgPro: 2.328 ± 0.042	2.437ArgGln: 2.437 ± 0.046	3.854ArgArg: 3.854 ± 0.06	3.866ArgSer: 3.866 ± 0.059	3.011ArgThr: 3.011 ± 0.042	3.865ArgVal: 3.865 ± 0.047	0.934ArgTrp: 0.934 ± 0.025	1.579ArgTyr: 1.579 ± 0.027	0.0ArgXaa: 0.0 ± 0.0
Ser	5.822SerAla: 5.822 ± 0.06	0.701SerCys: 0.701 ± 0.023	4.823SerAsp: 4.823 ± 0.074	4.372SerGlu: 4.372 ± 0.057	3.002SerPhe: 3.002 ± 0.043	6.083SerGly: 6.083 ± 0.1	1.343SerHis: 1.343 ± 0.027	4.329SerIle: 4.329 ± 0.052	3.143SerLys: 3.143 ± 0.048	6.595SerLeu: 6.595 ± 0.069	1.72SerMet: 1.72 ± 0.033	2.87SerAsn: 2.87 ± 0.05	3.263SerPro: 3.263 ± 0.041	2.797SerGln: 2.797 ± 0.04	4.065SerArg: 4.065 ± 0.063	4.926SerSer: 4.926 ± 0.067	3.872SerThr: 3.872 ± 0.061	5.06SerVal: 5.06 ± 0.056	1.017SerTrp: 1.017 ± 0.026	1.475SerTyr: 1.475 ± 0.031	0.0SerXaa: 0.0 ± 0.0
Thr	4.893ThrAla: 4.893 ± 0.09	0.532ThrCys: 0.532 ± 0.015	3.481ThrAsp: 3.481 ± 0.073	3.326ThrGlu: 3.326 ± 0.049	2.414ThrPhe: 2.414 ± 0.058	4.621ThrGly: 4.621 ± 0.083	1.001ThrHis: 1.001 ± 0.025	3.458ThrIle: 3.458 ± 0.077	2.101ThrLys: 2.101 ± 0.04	5.139ThrLeu: 5.139 ± 0.054	1.232ThrMet: 1.232 ± 0.026	1.942ThrAsn: 1.942 ± 0.04	2.931ThrPro: 2.931 ± 0.047	1.863ThrGln: 1.863 ± 0.033	2.905ThrArg: 2.905 ± 0.046	3.662ThrSer: 3.662 ± 0.056	3.236ThrThr: 3.236 ± 0.088	4.214ThrVal: 4.214 ± 0.089	0.761ThrTrp: 0.761 ± 0.022	1.229ThrTyr: 1.229 ± 0.029	0.0ThrXaa: 0.0 ± 0.0
Val	7.323ValAla: 7.323 ± 0.073	0.931ValCys: 0.931 ± 0.023	5.041ValAsp: 5.041 ± 0.065	5.052ValGlu: 5.052 ± 0.062	2.891ValPhe: 2.891 ± 0.037	5.225ValGly: 5.225 ± 0.065	1.321ValHis: 1.321 ± 0.028	3.796ValIle: 3.796 ± 0.054	2.792ValLys: 2.792 ± 0.05	6.145ValLeu: 6.145 ± 0.068	1.604ValMet: 1.604 ± 0.032	2.548ValAsn: 2.548 ± 0.045	3.198ValPro: 3.198 ± 0.056	2.415ValGln: 2.415 ± 0.04	3.975ValArg: 3.975 ± 0.046	5.276ValSer: 5.276 ± 0.07	4.05ValThr: 4.05 ± 0.09	5.861ValVal: 5.861 ± 0.073	0.915ValTrp: 0.915 ± 0.022	1.642ValTyr: 1.642 ± 0.032	0.0ValXaa: 0.0 ± 0.0
Trp	0.94TrpAla: 0.94 ± 0.025	0.184TrpCys: 0.184 ± 0.011	0.76TrpAsp: 0.76 ± 0.024	0.672TrpGlu: 0.672 ± 0.018	0.676TrpPhe: 0.676 ± 0.017	0.755TrpGly: 0.755 ± 0.024	0.367TrpHis: 0.367 ± 0.015	0.872TrpIle: 0.872 ± 0.023	0.75TrpLys: 0.75 ± 0.022	1.611TrpLeu: 1.611 ± 0.036	0.418TrpMet: 0.418 ± 0.015	0.619TrpAsn: 0.619 ± 0.021	0.604TrpPro: 0.604 ± 0.019	0.683TrpGln: 0.683 ± 0.018	0.842TrpArg: 0.842 ± 0.022	1.044TrpSer: 1.044 ± 0.027	0.794TrpThr: 0.794 ± 0.026	0.841TrpVal: 0.841 ± 0.022	0.253TrpTrp: 0.253 ± 0.013	0.371TrpTyr: 0.371 ± 0.015	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.906TyrAla: 1.906 ± 0.035	0.352TyrCys: 0.352 ± 0.013	1.633TyrAsp: 1.633 ± 0.035	1.598TyrGlu: 1.598 ± 0.032	1.099TyrPhe: 1.099 ± 0.026	1.897TyrGly: 1.897 ± 0.035	0.515TyrHis: 0.515 ± 0.018	0.888TyrIle: 0.888 ± 0.023	0.838TyrLys: 0.838 ± 0.023	2.226TyrLeu: 2.226 ± 0.032	0.42TyrMet: 0.42 ± 0.014	0.791TyrAsn: 0.791 ± 0.023	1.045TyrPro: 1.045 ± 0.026	1.11TyrGln: 1.11 ± 0.026	1.829TyrArg: 1.829 ± 0.036	1.631TyrSer: 1.631 ± 0.031	1.065TyrThr: 1.065 ± 0.036	1.631TyrVal: 1.631 ± 0.03	0.402TyrTrp: 0.402 ± 0.015	0.664TyrTyr: 0.664 ± 0.019	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 5083 proteins (1929523 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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