Amino acid dipepetide frequency for Solimonas fluminis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	18.412AlaAla: 18.412 ± 0.186	1.353AlaCys: 1.353 ± 0.039	6.456AlaAsp: 6.456 ± 0.073	7.721AlaGlu: 7.721 ± 0.097	3.675AlaPhe: 3.675 ± 0.051	11.397AlaGly: 11.397 ± 0.13	2.133AlaHis: 2.133 ± 0.045	4.73AlaIle: 4.73 ± 0.066	3.435AlaLys: 3.435 ± 0.063	13.954AlaLeu: 13.954 ± 0.138	3.191AlaMet: 3.191 ± 0.053	2.601AlaAsn: 2.601 ± 0.058	6.315AlaPro: 6.315 ± 0.074	5.199AlaGln: 5.199 ± 0.067	9.093AlaArg: 9.093 ± 0.105	5.963AlaSer: 5.963 ± 0.076	5.152AlaThr: 5.152 ± 0.084	8.509AlaVal: 8.509 ± 0.089	1.917AlaTrp: 1.917 ± 0.04	2.591AlaTyr: 2.591 ± 0.049	0.001AlaXaa: 0.001 ± 0.001
Cys	1.136CysAla: 1.136 ± 0.033	0.144CysCys: 0.144 ± 0.012	0.499CysAsp: 0.499 ± 0.021	0.552CysGlu: 0.552 ± 0.018	0.307CysPhe: 0.307 ± 0.014	1.055CysGly: 1.055 ± 0.032	0.307CysHis: 0.307 ± 0.02	0.362CysIle: 0.362 ± 0.016	0.239CysLys: 0.239 ± 0.012	0.887CysLeu: 0.887 ± 0.026	0.177CysMet: 0.177 ± 0.012	0.239CysAsn: 0.239 ± 0.014	0.527CysPro: 0.527 ± 0.024	0.27CysGln: 0.27 ± 0.013	0.754CysArg: 0.754 ± 0.023	0.607CysSer: 0.607 ± 0.021	0.433CysThr: 0.433 ± 0.018	0.672CysVal: 0.672 ± 0.023	0.126CysTrp: 0.126 ± 0.011	0.235CysTyr: 0.235 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	6.568AspAla: 6.568 ± 0.07	0.537AspCys: 0.537 ± 0.021	2.611AspAsp: 2.611 ± 0.046	3.229AspGlu: 3.229 ± 0.046	2.173AspPhe: 2.173 ± 0.041	5.001AspGly: 5.001 ± 0.078	1.1AspHis: 1.1 ± 0.031	2.547AspIle: 2.547 ± 0.058	1.574AspLys: 1.574 ± 0.039	5.668AspLeu: 5.668 ± 0.071	1.007AspMet: 1.007 ± 0.028	1.238AspAsn: 1.238 ± 0.03	3.395AspPro: 3.395 ± 0.054	1.644AspGln: 1.644 ± 0.038	3.743AspArg: 3.743 ± 0.055	2.568AspSer: 2.568 ± 0.05	2.327AspThr: 2.327 ± 0.046	3.492AspVal: 3.492 ± 0.058	1.042AspTrp: 1.042 ± 0.03	1.693AspTyr: 1.693 ± 0.04	0.0AspXaa: 0.0 ± 0.0
Glu	7.446GluAla: 7.446 ± 0.074	0.429GluCys: 0.429 ± 0.019	2.634GluAsp: 2.634 ± 0.043	3.179GluGlu: 3.179 ± 0.059	1.923GluPhe: 1.923 ± 0.04	4.432GluGly: 4.432 ± 0.054	1.275GluHis: 1.275 ± 0.032	2.921GluIle: 2.921 ± 0.042	2.064GluLys: 2.064 ± 0.046	6.725GluLeu: 6.725 ± 0.088	1.308GluMet: 1.308 ± 0.034	1.373GluAsn: 1.373 ± 0.031	2.89GluPro: 2.89 ± 0.059	2.895GluGln: 2.895 ± 0.053	5.164GluArg: 5.164 ± 0.067	2.729GluSer: 2.729 ± 0.046	2.701GluThr: 2.701 ± 0.043	3.895GluVal: 3.895 ± 0.056	0.731GluTrp: 0.731 ± 0.023	1.378GluTyr: 1.378 ± 0.036	0.0GluXaa: 0.0 ± 0.0
Phe	3.895PheAla: 3.895 ± 0.058	0.394PheCys: 0.394 ± 0.017	2.27PheAsp: 2.27 ± 0.049	2.053PheGlu: 2.053 ± 0.043	1.28PhePhe: 1.28 ± 0.035	3.376PheGly: 3.376 ± 0.054	0.781PheHis: 0.781 ± 0.025	1.424PheIle: 1.424 ± 0.032	0.983PheLys: 0.983 ± 0.027	3.29PheLeu: 3.29 ± 0.055	0.768PheMet: 0.768 ± 0.021	1.059PheAsn: 1.059 ± 0.034	1.578PhePro: 1.578 ± 0.036	1.059PheGln: 1.059 ± 0.026	2.391PheArg: 2.391 ± 0.046	2.153PheSer: 2.153 ± 0.045	1.87PheThr: 1.87 ± 0.038	2.395PheVal: 2.395 ± 0.043	0.514PheTrp: 0.514 ± 0.022	0.91PheTyr: 0.91 ± 0.031	0.0PheXaa: 0.0 ± 0.0
Gly	9.203GlyAla: 9.203 ± 0.112	0.977GlyCys: 0.977 ± 0.03	4.476GlyAsp: 4.476 ± 0.087	5.206GlyGlu: 5.206 ± 0.062	3.41GlyPhe: 3.41 ± 0.049	8.066GlyGly: 8.066 ± 0.138	1.92GlyHis: 1.92 ± 0.036	4.265GlyIle: 4.265 ± 0.063	3.294GlyLys: 3.294 ± 0.063	9.641GlyLeu: 9.641 ± 0.094	2.188GlyMet: 2.188 ± 0.048	2.343GlyAsn: 2.343 ± 0.06	3.455GlyPro: 3.455 ± 0.056	3.368GlyGln: 3.368 ± 0.05	6.427GlyArg: 6.427 ± 0.077	5.204GlySer: 5.204 ± 0.095	4.248GlyThr: 4.248 ± 0.092	6.116GlyVal: 6.116 ± 0.064	1.596GlyTrp: 1.596 ± 0.033	2.691GlyTyr: 2.691 ± 0.051	0.001GlyXaa: 0.001 ± 0.001
His	2.418HisAla: 2.418 ± 0.046	0.267HisCys: 0.267 ± 0.013	1.095HisAsp: 1.095 ± 0.03	1.13HisGlu: 1.13 ± 0.027	0.875HisPhe: 0.875 ± 0.029	2.105HisGly: 2.105 ± 0.041	0.639HisHis: 0.639 ± 0.025	0.825HisIle: 0.825 ± 0.022	0.523HisLys: 0.523 ± 0.022	2.098HisLeu: 2.098 ± 0.041	0.438HisMet: 0.438 ± 0.019	0.497HisAsn: 0.497 ± 0.02	1.43HisPro: 1.43 ± 0.035	0.671HisGln: 0.671 ± 0.025	1.633HisArg: 1.633 ± 0.037	1.007HisSer: 1.007 ± 0.031	0.858HisThr: 0.858 ± 0.025	1.333HisVal: 1.333 ± 0.036	0.409HisTrp: 0.409 ± 0.017	0.669HisTyr: 0.669 ± 0.022	0.0HisXaa: 0.0 ± 0.0
Ile	5.525IleAla: 5.525 ± 0.072	0.403IleCys: 0.403 ± 0.017	2.872IleAsp: 2.872 ± 0.046	2.894IleGlu: 2.894 ± 0.056	1.188IlePhe: 1.188 ± 0.029	4.139IleGly: 4.139 ± 0.074	0.88IleHis: 0.88 ± 0.026	1.363IleIle: 1.363 ± 0.036	1.305IleLys: 1.305 ± 0.033	3.595IleLeu: 3.595 ± 0.055	0.654IleMet: 0.654 ± 0.026	1.331IleAsn: 1.331 ± 0.034	2.239IlePro: 2.239 ± 0.049	1.284IleGln: 1.284 ± 0.031	3.062IleArg: 3.062 ± 0.052	2.236IleSer: 2.236 ± 0.037	2.223IleThr: 2.223 ± 0.049	3.197IleVal: 3.197 ± 0.058	0.507IleTrp: 0.507 ± 0.018	0.997IleTyr: 0.997 ± 0.027	0.0IleXaa: 0.0 ± 0.0
Lys	3.932LysAla: 3.932 ± 0.064	0.191LysCys: 0.191 ± 0.013	1.63LysAsp: 1.63 ± 0.044	1.525LysGlu: 1.525 ± 0.041	0.87LysPhe: 0.87 ± 0.026	2.398LysGly: 2.398 ± 0.049	0.623LysHis: 0.623 ± 0.022	1.371LysIle: 1.371 ± 0.035	1.32LysLys: 1.32 ± 0.041	3.789LysLeu: 3.789 ± 0.063	0.712LysMet: 0.712 ± 0.023	0.83LysAsn: 0.83 ± 0.029	2.237LysPro: 2.237 ± 0.047	1.21LysGln: 1.21 ± 0.032	2.191LysArg: 2.191 ± 0.048	1.501LysSer: 1.501 ± 0.036	1.713LysThr: 1.713 ± 0.033	2.208LysVal: 2.208 ± 0.053	0.324LysTrp: 0.324 ± 0.014	0.704LysTyr: 0.704 ± 0.023	0.001LysXaa: 0.001 ± 0.001
Leu	14.477LeuAla: 14.477 ± 0.128	1.033LeuCys: 1.033 ± 0.026	6.206LeuAsp: 6.206 ± 0.069	6.022LeuGlu: 6.022 ± 0.072	3.664LeuPhe: 3.664 ± 0.064	9.149LeuGly: 9.149 ± 0.097	2.253LeuHis: 2.253 ± 0.045	3.824LeuIle: 3.824 ± 0.054	3.767LeuLys: 3.767 ± 0.062	12.601LeuLeu: 12.601 ± 0.154	2.377LeuMet: 2.377 ± 0.039	2.627LeuAsn: 2.627 ± 0.043	6.87LeuPro: 6.87 ± 0.086	4.456LeuGln: 4.456 ± 0.067	9.26LeuArg: 9.26 ± 0.114	6.288LeuSer: 6.288 ± 0.074	4.824LeuThr: 4.824 ± 0.063	7.349LeuVal: 7.349 ± 0.087	1.403LeuTrp: 1.403 ± 0.034	2.242LeuTyr: 2.242 ± 0.041	0.0LeuXaa: 0.0 ± 0.0
Met	2.638MetAla: 2.638 ± 0.047	0.155MetCys: 0.155 ± 0.01	1.112MetAsp: 1.112 ± 0.027	1.14MetGlu: 1.14 ± 0.033	0.641MetPhe: 0.641 ± 0.022	1.676MetGly: 1.676 ± 0.041	0.456MetHis: 0.456 ± 0.019	0.954MetIle: 0.954 ± 0.027	1.017MetLys: 1.017 ± 0.029	2.424MetLeu: 2.424 ± 0.045	0.525MetMet: 0.525 ± 0.022	0.774MetAsn: 0.774 ± 0.025	1.466MetPro: 1.466 ± 0.038	0.939MetGln: 0.939 ± 0.027	1.688MetArg: 1.688 ± 0.035	1.59MetSer: 1.59 ± 0.036	1.362MetThr: 1.362 ± 0.03	1.35MetVal: 1.35 ± 0.034	0.174MetTrp: 0.174 ± 0.012	0.334MetTyr: 0.334 ± 0.015	0.0MetXaa: 0.0 ± 0.0
Asn	2.924AsnAla: 2.924 ± 0.06	0.276AsnCys: 0.276 ± 0.014	1.226AsnAsp: 1.226 ± 0.035	1.132AsnGlu: 1.132 ± 0.032	0.92AsnPhe: 0.92 ± 0.028	2.411AsnGly: 2.411 ± 0.062	0.524AsnHis: 0.524 ± 0.019	1.191AsnIle: 1.191 ± 0.033	0.698AsnLys: 0.698 ± 0.025	2.849AsnLeu: 2.849 ± 0.052	0.473AsnMet: 0.473 ± 0.019	0.776AsnAsn: 0.776 ± 0.03	1.914AsnPro: 1.914 ± 0.053	0.89AsnGln: 0.89 ± 0.03	1.786AsnArg: 1.786 ± 0.035	1.217AsnSer: 1.217 ± 0.044	1.261AsnThr: 1.261 ± 0.038	1.749AsnVal: 1.749 ± 0.037	0.387AsnTrp: 0.387 ± 0.016	0.705AsnTyr: 0.705 ± 0.025	0.0AsnXaa: 0.0 ± 0.0
Pro	7.789ProAla: 7.789 ± 0.093	0.378ProCys: 0.378 ± 0.016	3.314ProAsp: 3.314 ± 0.052	4.025ProGlu: 4.025 ± 0.065	1.736ProPhe: 1.736 ± 0.032	5.281ProGly: 5.281 ± 0.066	1.008ProHis: 1.008 ± 0.03	1.756ProIle: 1.756 ± 0.035	1.589ProLys: 1.589 ± 0.04	5.812ProLeu: 5.812 ± 0.079	1.304ProMet: 1.304 ± 0.029	1.212ProAsn: 1.212 ± 0.033	3.397ProPro: 3.397 ± 0.062	2.394ProGln: 2.394 ± 0.047	3.732ProArg: 3.732 ± 0.062	2.579ProSer: 2.579 ± 0.043	2.18ProThr: 2.18 ± 0.039	4.248ProVal: 4.248 ± 0.059	0.806ProTrp: 0.806 ± 0.023	1.24ProTyr: 1.24 ± 0.033	0.001ProXaa: 0.001 ± 0.001
Gln	5.453GlnAla: 5.453 ± 0.089	0.274GlnCys: 0.274 ± 0.014	1.834GlnAsp: 1.834 ± 0.036	1.896GlnGlu: 1.896 ± 0.043	1.325GlnPhe: 1.325 ± 0.035	3.246GlnGly: 3.246 ± 0.057	0.868GlnHis: 0.868 ± 0.031	1.593GlnIle: 1.593 ± 0.036	1.305GlnLys: 1.305 ± 0.034	4.264GlnLeu: 4.264 ± 0.063	0.887GlnMet: 0.887 ± 0.026	0.853GlnAsn: 0.853 ± 0.03	2.29GlnPro: 2.29 ± 0.046	1.942GlnGln: 1.942 ± 0.044	3.456GlnArg: 3.456 ± 0.058	1.722GlnSer: 1.722 ± 0.04	1.631GlnThr: 1.631 ± 0.036	2.909GlnVal: 2.909 ± 0.045	0.599GlnTrp: 0.599 ± 0.021	0.912GlnTyr: 0.912 ± 0.027	0.0GlnXaa: 0.0 ± 0.0
Arg	7.807ArgAla: 7.807 ± 0.092	0.667ArgCys: 0.667 ± 0.024	4.002ArgAsp: 4.002 ± 0.057	4.991ArgGlu: 4.991 ± 0.076	2.95ArgPhe: 2.95 ± 0.054	5.617ArgGly: 5.617 ± 0.076	1.923ArgHis: 1.923 ± 0.043	3.826ArgIle: 3.826 ± 0.062	2.235ArgLys: 2.235 ± 0.045	9.25ArgLeu: 9.25 ± 0.109	1.891ArgMet: 1.891 ± 0.036	1.952ArgAsn: 1.952 ± 0.041	3.81ArgPro: 3.81 ± 0.061	3.294ArgGln: 3.294 ± 0.055	6.666ArgArg: 6.666 ± 0.098	3.928ArgSer: 3.928 ± 0.057	2.88ArgThr: 2.88 ± 0.043	5.243ArgVal: 5.243 ± 0.062	1.349ArgTrp: 1.349 ± 0.036	2.384ArgTyr: 2.384 ± 0.05	0.0ArgXaa: 0.0 ± 0.0
Ser	6.119SerAla: 6.119 ± 0.099	0.539SerCys: 0.539 ± 0.023	2.524SerAsp: 2.524 ± 0.048	2.607SerGlu: 2.607 ± 0.05	2.137SerPhe: 2.137 ± 0.043	5.588SerGly: 5.588 ± 0.098	1.042SerHis: 1.042 ± 0.025	2.242SerIle: 2.242 ± 0.048	1.431SerLys: 1.431 ± 0.036	5.906SerLeu: 5.906 ± 0.078	1.196SerMet: 1.196 ± 0.03	1.282SerAsn: 1.282 ± 0.033	2.915SerPro: 2.915 ± 0.048	1.774SerGln: 1.774 ± 0.035	3.96SerArg: 3.96 ± 0.057	3.038SerSer: 3.038 ± 0.067	2.446SerThr: 2.446 ± 0.052	3.647SerVal: 3.647 ± 0.063	0.829SerTrp: 0.829 ± 0.024	1.45SerTyr: 1.45 ± 0.032	0.001SerXaa: 0.001 ± 0.001
Thr	5.742ThrAla: 5.742 ± 0.096	0.413ThrCys: 0.413 ± 0.019	2.294ThrAsp: 2.294 ± 0.043	2.354ThrGlu: 2.354 ± 0.04	1.351ThrPhe: 1.351 ± 0.034	4.479ThrGly: 4.479 ± 0.094	0.912ThrHis: 0.912 ± 0.029	1.85ThrIle: 1.85 ± 0.042	1.075ThrLys: 1.075 ± 0.037	5.764ThrLeu: 5.764 ± 0.069	0.905ThrMet: 0.905 ± 0.026	1.048ThrAsn: 1.048 ± 0.035	3.262ThrPro: 3.262 ± 0.054	1.691ThrGln: 1.691 ± 0.041	3.361ThrArg: 3.361 ± 0.054	2.116ThrSer: 2.116 ± 0.046	2.29ThrThr: 2.29 ± 0.05	3.743ThrVal: 3.743 ± 0.065	0.623ThrTrp: 0.623 ± 0.021	1.018ThrTyr: 1.018 ± 0.029	0.0ThrXaa: 0.0 ± 0.0
Val	8.224ValAla: 8.224 ± 0.09	0.694ValCys: 0.694 ± 0.024	3.939ValAsp: 3.939 ± 0.062	4.373ValGlu: 4.373 ± 0.07	2.485ValPhe: 2.485 ± 0.049	5.36ValGly: 5.36 ± 0.08	1.415ValHis: 1.415 ± 0.032	3.27ValIle: 3.27 ± 0.058	2.221ValLys: 2.221 ± 0.052	7.512ValLeu: 7.512 ± 0.081	1.595ValMet: 1.595 ± 0.036	2.066ValAsn: 2.066 ± 0.046	3.756ValPro: 3.756 ± 0.053	2.535ValGln: 2.535 ± 0.044	4.815ValArg: 4.815 ± 0.064	4.0ValSer: 4.0 ± 0.058	3.915ValThr: 3.915 ± 0.079	5.386ValVal: 5.386 ± 0.072	0.854ValTrp: 0.854 ± 0.025	1.648ValTyr: 1.648 ± 0.039	0.001ValXaa: 0.001 ± 0.001
Trp	1.337TrpAla: 1.337 ± 0.032	0.151TrpCys: 0.151 ± 0.011	0.679TrpAsp: 0.679 ± 0.021	0.681TrpGlu: 0.681 ± 0.024	0.57TrpPhe: 0.57 ± 0.022	1.04TrpGly: 1.04 ± 0.026	0.346TrpHis: 0.346 ± 0.015	0.688TrpIle: 0.688 ± 0.019	0.53TrpLys: 0.53 ± 0.02	2.032TrpLeu: 2.032 ± 0.044	0.403TrpMet: 0.403 ± 0.015	0.483TrpAsn: 0.483 ± 0.018	0.726TrpPro: 0.726 ± 0.024	0.778TrpGln: 0.778 ± 0.025	1.237TrpArg: 1.237 ± 0.033	0.842TrpSer: 0.842 ± 0.026	0.786TrpThr: 0.786 ± 0.024	0.925TrpVal: 0.925 ± 0.025	0.281TrpTrp: 0.281 ± 0.016	0.317TrpTyr: 0.317 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.754TyrAla: 2.754 ± 0.044	0.251TyrCys: 0.251 ± 0.012	1.483TyrAsp: 1.483 ± 0.04	1.38TyrGlu: 1.38 ± 0.034	0.964TyrPhe: 0.964 ± 0.027	2.28TyrGly: 2.28 ± 0.043	0.514TyrHis: 0.514 ± 0.021	0.893TyrIle: 0.893 ± 0.024	0.673TyrLys: 0.673 ± 0.024	2.632TyrLeu: 2.632 ± 0.044	0.417TyrMet: 0.417 ± 0.017	0.725TyrAsn: 0.725 ± 0.026	1.305TyrPro: 1.305 ± 0.032	0.965TyrGln: 0.965 ± 0.028	2.246TyrArg: 2.246 ± 0.041	1.388TyrSer: 1.388 ± 0.035	1.192TyrThr: 1.192 ± 0.03	1.698TyrVal: 1.698 ± 0.04	0.363TyrTrp: 0.363 ± 0.016	0.686TyrTyr: 0.686 ± 0.024	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.001XaaGlu: 0.001 ± 0.001	0.0XaaPhe: 0.0 ± 0.0	0.001XaaGly: 0.001 ± 0.001	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.001XaaLeu: 0.001 ± 0.001	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.001XaaPro: 0.001 ± 0.001	0.001XaaGln: 0.001 ± 0.001	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4276 proteins (1399617 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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