Human papillomavirus 11

Taxonomy: Viruses; Monodnaviria; Shotokuvirae; Cossaviricota; Papovaviricetes; Zurhausenvirales; Papillomaviridae; Firstpapillomavirinae; Alphapapillomavirus; Alphapapillomavirus 10

Average proteome isoelectric point is 6.56

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 10 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>sp|P0DKA1|VE8E2_HPV11 Protein E8^E2C OS=Human papillomavirus 11 OX=10580 PE=3 SV=1
MM1 pKa = 7.58HH2 pKa = 7.07GRR4 pKa = 11.84LVTLKK9 pKa = 10.82DD10 pKa = 3.21IVLDD14 pKa = 4.05LQPPDD19 pKa = 3.7PVGLHH24 pKa = 6.81CYY26 pKa = 8.4EE27 pKa = 4.04QLEE30 pKa = 4.49DD31 pKa = 3.73SSEE34 pKa = 4.46DD35 pKa = 3.66EE36 pKa = 3.83VDD38 pKa = 5.0KK39 pKa = 11.44VDD41 pKa = 4.56KK42 pKa = 10.96QDD44 pKa = 3.67AQPLTQHH51 pKa = 5.55YY52 pKa = 10.26QILTCCCGCDD62 pKa = 3.33SNVRR66 pKa = 11.84LVVEE70 pKa = 4.68CTDD73 pKa = 2.97GDD75 pKa = 3.62IRR77 pKa = 11.84QLQDD81 pKa = 3.84LLLGTLNIVCPICAPKK97 pKa = 9.98PP98 pKa = 3.56

Molecular weight: 10.89 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>sp|P69901|VE5B_HPV11 Probable protein E5B OS=Human papillomavirus 11 OX=10580 PE=4 SV=1
MM1 pKa = 8.0AILKK5 pKa = 8.93WKK7 pKa = 9.15LQRR10 pKa = 11.84STVRR14 pKa = 11.84EE15 pKa = 3.8VSIAEE20 pKa = 4.03PTTYY24 pKa = 10.43TPAQTTAPTVSACTTEE40 pKa = 5.05DD41 pKa = 3.67GVSAPPRR48 pKa = 11.84KK49 pKa = 9.19RR50 pKa = 11.84ARR52 pKa = 11.84GPSTNNTLCVANIRR66 pKa = 11.84SVDD69 pKa = 3.46STINNIVTDD78 pKa = 4.35NYY80 pKa = 11.13NKK82 pKa = 9.88HH83 pKa = 4.73QRR85 pKa = 11.84RR86 pKa = 11.84NNCHH90 pKa = 6.05SAATPIVQLQGDD102 pKa = 4.68SNCLKK107 pKa = 10.4CFRR110 pKa = 11.84YY111 pKa = 9.99RR112 pKa = 11.84LNDD115 pKa = 3.26KK116 pKa = 10.27YY117 pKa = 11.47KK118 pKa = 10.76HH119 pKa = 5.65LFEE122 pKa = 5.08LASSTWHH129 pKa = 5.89WASPEE134 pKa = 4.0APHH137 pKa = 6.82KK138 pKa = 10.52NAIVTLTYY146 pKa = 10.53SSEE149 pKa = 3.97EE150 pKa = 3.71QRR152 pKa = 11.84QQFLNSVKK160 pKa = 9.74IPPTIRR166 pKa = 11.84HH167 pKa = 5.49KK168 pKa = 10.91VGFMSLHH175 pKa = 6.16LLL177 pKa = 3.85

Molecular weight: 19.95 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

10

0

10

2652

74

649

265.2

29.72

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

6.222 ± 0.449

2.828 ± 0.665

5.354 ± 0.676

5.053 ± 0.787

3.733 ± 0.381

5.317 ± 0.787

3.017 ± 0.289

5.166 ± 0.709

5.128 ± 0.825

8.522 ± 1.154

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.848 ± 0.292

4.223 ± 0.629

6.373 ± 1.285

4.299 ± 0.359

4.713 ± 0.382

7.504 ± 0.681

8.145 ± 0.803

7.315 ± 0.574

1.621 ± 0.215

3.62 ± 0.396
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski