Amino acid dipepetide frequency for Tapirape virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.539AlaAla: 2.539 ± 2.44
2.285AlaCys: 2.285 ± 1.316
3.046AlaAsp: 3.046 ± 0.695
3.046AlaGlu: 3.046 ± 0.261
1.777AlaPhe: 1.777 ± 0.537
2.539AlaGly: 2.539 ± 3.164
0.762AlaHis: 0.762 ± 0.475
4.824AlaIle: 4.824 ± 3.607
5.077AlaLys: 5.077 ± 1.035
4.062AlaLeu: 4.062 ± 0.944
2.031AlaMet: 2.031 ± 1.457
2.031AlaAsn: 2.031 ± 0.472
1.269AlaPro: 1.269 ± 0.678
1.777AlaGln: 1.777 ± 0.581
2.285AlaArg: 2.285 ± 0.564
1.523AlaSer: 1.523 ± 0.627
3.046AlaThr: 3.046 ± 0.86
1.777AlaVal: 1.777 ± 1.471
0.508AlaTrp: 0.508 ± 0.317
1.015AlaTyr: 1.015 ± 0.268
0.0AlaXaa: 0.0 ± 0.0
Cys
0.508CysAla: 0.508 ± 0.317
0.0CysCys: 0.0 ± 0.0
1.269CysAsp: 1.269 ± 1.112
2.031CysGlu: 2.031 ± 0.472
2.793CysPhe: 2.793 ± 1.113
2.031CysGly: 2.031 ± 1.779
1.269CysHis: 1.269 ± 0.768
2.031CysIle: 2.031 ± 0.783
2.285CysLys: 2.285 ± 1.654
2.539CysLeu: 2.539 ± 1.208
1.015CysMet: 1.015 ± 0.704
2.285CysAsn: 2.285 ± 0.711
2.031CysPro: 2.031 ± 0.783
0.508CysGln: 0.508 ± 0.317
1.015CysArg: 1.015 ± 0.548
2.539CysSer: 2.539 ± 0.907
1.015CysThr: 1.015 ± 0.268
1.015CysVal: 1.015 ± 0.548
0.0CysTrp: 0.0 ± 0.0
1.269CysTyr: 1.269 ± 0.289
0.0CysXaa: 0.0 ± 0.0
Asp
2.793AspAla: 2.793 ± 1.238
1.015AspCys: 1.015 ± 0.548
3.554AspAsp: 3.554 ± 1.189
4.062AspGlu: 4.062 ± 1.879
2.793AspPhe: 2.793 ± 0.434
2.539AspGly: 2.539 ± 0.907
0.762AspHis: 0.762 ± 0.191
4.824AspIle: 4.824 ± 0.44
3.3AspLys: 3.3 ± 0.974
6.601AspLeu: 6.601 ± 0.569
2.285AspMet: 2.285 ± 0.543
2.285AspAsn: 2.285 ± 1.448
2.539AspPro: 2.539 ± 0.697
2.285AspGln: 2.285 ± 0.796
2.031AspArg: 2.031 ± 0.649
3.554AspSer: 3.554 ± 0.415
1.777AspThr: 1.777 ± 0.597
4.062AspVal: 4.062 ± 0.329
1.015AspTrp: 1.015 ± 1.652
3.554AspTyr: 3.554 ± 1.566
0.0AspXaa: 0.0 ± 0.0
Glu
2.539GluAla: 2.539 ± 0.697
2.031GluCys: 2.031 ± 0.783
3.046GluAsp: 3.046 ± 0.86
4.57GluGlu: 4.57 ± 1.982
3.3GluPhe: 3.3 ± 1.727
1.523GluGly: 1.523 ± 0.662
1.777GluHis: 1.777 ± 0.828
6.855GluIle: 6.855 ± 1.723
4.57GluLys: 4.57 ± 2.719
5.839GluLeu: 5.839 ± 0.947
1.523GluMet: 1.523 ± 1.21
2.793GluAsn: 2.793 ± 0.659
1.523GluPro: 1.523 ± 0.627
2.285GluGln: 2.285 ± 0.852
4.062GluArg: 4.062 ± 1.298
6.855GluSer: 6.855 ± 1.067
4.062GluThr: 4.062 ± 0.942
2.539GluVal: 2.539 ± 0.669
0.508GluTrp: 0.508 ± 0.134
3.554GluTyr: 3.554 ± 0.768
0.0GluXaa: 0.0 ± 0.0
Phe
2.031PheAla: 2.031 ± 0.535
2.285PheCys: 2.285 ± 0.796
3.3PheAsp: 3.3 ± 1.12
3.554PheGlu: 3.554 ± 1.488
3.3PhePhe: 3.3 ± 0.858
1.269PheGly: 1.269 ± 0.289
1.015PheHis: 1.015 ± 0.268
4.062PheIle: 4.062 ± 0.329
5.077PheLys: 5.077 ± 0.812
5.331PheLeu: 5.331 ± 1.167
1.015PheMet: 1.015 ± 0.548
2.539PheAsn: 2.539 ± 1.304
1.015PhePro: 1.015 ± 0.795
1.523PheGln: 1.523 ± 0.627
1.523PheArg: 1.523 ± 0.95
4.824PheSer: 4.824 ± 0.948
2.793PheThr: 2.793 ± 1.113
2.031PheVal: 2.031 ± 0.489
0.254PheTrp: 0.254 ± 0.158
2.285PheTyr: 2.285 ± 0.535
0.0PheXaa: 0.0 ± 0.0
Gly
1.269GlyAla: 1.269 ± 0.861
2.539GlyCys: 2.539 ± 0.406
2.031GlyAsp: 2.031 ± 0.528
4.062GlyGlu: 4.062 ± 2.117
1.777GlyPhe: 1.777 ± 0.878
2.539GlyGly: 2.539 ± 0.406
1.269GlyHis: 1.269 ± 0.289
3.046GlyIle: 3.046 ± 1.324
3.3GlyLys: 3.3 ± 0.308
5.331GlyLeu: 5.331 ± 0.28
1.015GlyMet: 1.015 ± 0.468
2.285GlyAsn: 2.285 ± 0.535
1.777GlyPro: 1.777 ± 0.409
2.031GlyGln: 2.031 ± 0.939
2.031GlyArg: 2.031 ± 0.535
3.046GlySer: 3.046 ± 1.369
2.539GlyThr: 2.539 ± 0.985
3.046GlyVal: 3.046 ± 2.225
0.508GlyTrp: 0.508 ± 0.134
1.269GlyTyr: 1.269 ± 0.453
0.0GlyXaa: 0.0 ± 0.0
His
1.015HisAla: 1.015 ± 0.268
0.762HisCys: 0.762 ± 0.191
0.762HisAsp: 0.762 ± 0.191
1.269HisGlu: 1.269 ± 0.474
1.269HisPhe: 1.269 ± 0.861
1.777HisGly: 1.777 ± 0.581
0.254HisHis: 0.254 ± 0.158
1.523HisIle: 1.523 ± 0.724
1.015HisLys: 1.015 ± 0.548
2.793HisLeu: 2.793 ± 0.664
0.508HisMet: 0.508 ± 0.445
1.015HisAsn: 1.015 ± 0.325
0.762HisPro: 0.762 ± 0.331
0.508HisGln: 0.508 ± 0.134
1.015HisArg: 1.015 ± 0.268
0.762HisSer: 0.762 ± 0.774
1.269HisThr: 1.269 ± 0.289
1.269HisVal: 1.269 ± 0.453
0.0HisTrp: 0.0 ± 0.0
1.015HisTyr: 1.015 ± 0.548
0.0HisXaa: 0.0 ± 0.0
Ile
3.808IleAla: 3.808 ± 1.214
2.285IleCys: 2.285 ± 1.316
6.347IleAsp: 6.347 ± 1.365
5.331IleGlu: 5.331 ± 1.323
3.3IlePhe: 3.3 ± 1.184
3.554IleGly: 3.554 ± 0.849
2.031IleHis: 2.031 ± 1.096
6.855IleIle: 6.855 ± 1.562
7.616IleLys: 7.616 ± 1.689
7.362IleLeu: 7.362 ± 0.797
2.285IleMet: 2.285 ± 0.537
4.57IleAsn: 4.57 ± 1.147
2.031IlePro: 2.031 ± 0.489
2.793IleGln: 2.793 ± 0.302
5.839IleArg: 5.839 ± 2.355
7.362IleSer: 7.362 ± 0.243
3.808IleThr: 3.808 ± 0.193
3.554IleVal: 3.554 ± 0.352
0.762IleTrp: 0.762 ± 0.475
2.031IleTyr: 2.031 ± 0.535
0.0IleXaa: 0.0 ± 0.0
Lys
3.046LysAla: 3.046 ± 1.182
3.046LysCys: 3.046 ± 1.978
4.824LysAsp: 4.824 ± 1.191
7.108LysGlu: 7.108 ± 1.536
2.539LysPhe: 2.539 ± 0.406
5.077LysGly: 5.077 ± 1.667
3.046LysHis: 3.046 ± 1.182
6.093LysIle: 6.093 ± 1.6
5.585LysLys: 5.585 ± 0.655
4.316LysLeu: 4.316 ± 1.865
2.793LysMet: 2.793 ± 1.238
3.046LysAsn: 3.046 ± 1.447
2.793LysPro: 2.793 ± 1.1
3.046LysGln: 3.046 ± 1.369
4.316LysArg: 4.316 ± 1.038
5.585LysSer: 5.585 ± 1.472
5.585LysThr: 5.585 ± 0.687
4.57LysVal: 4.57 ± 1.334
0.508LysTrp: 0.508 ± 0.317
1.777LysTyr: 1.777 ± 0.409
0.0LysXaa: 0.0 ± 0.0
Leu
5.585LeuAla: 5.585 ± 3.404
2.031LeuCys: 2.031 ± 0.535
6.347LeuAsp: 6.347 ± 0.549
4.062LeuGlu: 4.062 ± 0.329
6.347LeuPhe: 6.347 ± 0.765
5.585LeuGly: 5.585 ± 0.412
1.777LeuHis: 1.777 ± 0.509
7.616LeuIle: 7.616 ± 0.83
6.347LeuLys: 6.347 ± 2.296
6.601LeuLeu: 6.601 ± 2.239
3.808LeuMet: 3.808 ± 0.193
4.57LeuAsn: 4.57 ± 0.991
2.539LeuPro: 2.539 ± 0.697
2.285LeuGln: 2.285 ± 0.537
3.046LeuArg: 3.046 ± 0.261
7.87LeuSer: 7.87 ± 1.948
4.316LeuThr: 4.316 ± 1.201
3.554LeuVal: 3.554 ± 1.755
0.508LeuTrp: 0.508 ± 0.134
3.3LeuTyr: 3.3 ± 1.167
0.0LeuXaa: 0.0 ± 0.0
Met
3.046MetAla: 3.046 ± 2.111
0.0MetCys: 0.0 ± 0.0
1.523MetAsp: 1.523 ± 0.887
2.285MetGlu: 2.285 ± 0.535
1.269MetPhe: 1.269 ± 0.678
1.269MetGly: 1.269 ± 0.289
0.254MetHis: 0.254 ± 0.222
2.539MetIle: 2.539 ± 0.394
2.031MetLys: 2.031 ± 1.576
3.554MetLeu: 3.554 ± 0.13
1.015MetMet: 1.015 ± 0.325
1.015MetAsn: 1.015 ± 0.325
1.777MetPro: 1.777 ± 0.581
1.269MetGln: 1.269 ± 0.289
0.762MetArg: 0.762 ± 0.475
2.285MetSer: 2.285 ± 0.535
2.031MetThr: 2.031 ± 0.528
1.015MetVal: 1.015 ± 0.268
0.0MetTrp: 0.0 ± 0.0
1.015MetTyr: 1.015 ± 0.325
0.0MetXaa: 0.0 ± 0.0
Asn
4.316AsnAla: 4.316 ± 0.123
0.762AsnCys: 0.762 ± 0.331
4.062AsnAsp: 4.062 ± 1.076
2.285AsnGlu: 2.285 ± 0.537
2.031AsnPhe: 2.031 ± 0.528
1.523AsnGly: 1.523 ± 0.401
0.762AsnHis: 0.762 ± 0.191
4.062AsnIle: 4.062 ± 1.128
2.031AsnLys: 2.031 ± 0.939
3.554AsnLeu: 3.554 ± 1.162
1.777AsnMet: 1.777 ± 0.409
3.3AsnAsn: 3.3 ± 0.794
2.793AsnPro: 2.793 ± 2.25
2.031AsnGln: 2.031 ± 0.939
2.285AsnArg: 2.285 ± 0.564
1.777AsnSer: 1.777 ± 0.509
4.57AsnThr: 4.57 ± 0.991
3.046AsnVal: 3.046 ± 0.522
1.523AsnTrp: 1.523 ± 0.382
2.539AsnTyr: 2.539 ± 0.697
0.0AsnXaa: 0.0 ± 0.0
Pro
0.762ProAla: 0.762 ± 0.793
0.762ProCys: 0.762 ± 0.331
2.031ProAsp: 2.031 ± 1.407
2.793ProGlu: 2.793 ± 0.832
1.523ProPhe: 1.523 ± 0.382
2.285ProGly: 2.285 ± 0.796
0.254ProHis: 0.254 ± 0.222
3.3ProIle: 3.3 ± 0.974
2.285ProLys: 2.285 ± 1.316
3.808ProLeu: 3.808 ± 2.035
0.508ProMet: 0.508 ± 0.317
1.523ProAsn: 1.523 ± 0.887
1.015ProPro: 1.015 ± 0.325
0.762ProGln: 0.762 ± 0.191
1.523ProArg: 1.523 ± 0.95
3.3ProSer: 3.3 ± 0.759
2.031ProThr: 2.031 ± 0.783
1.015ProVal: 1.015 ± 0.634
0.508ProTrp: 0.508 ± 0.317
1.015ProTyr: 1.015 ± 0.325
0.0ProXaa: 0.0 ± 0.0
Gln
1.523GlnAla: 1.523 ± 0.382
0.762GlnCys: 0.762 ± 0.667
1.777GlnAsp: 1.777 ± 0.783
1.523GlnGlu: 1.523 ± 0.661
2.539GlnPhe: 2.539 ± 0.697
1.523GlnGly: 1.523 ± 0.662
0.762GlnHis: 0.762 ± 0.331
3.3GlnIle: 3.3 ± 1.12
4.57GlnLys: 4.57 ± 1.069
1.777GlnLeu: 1.777 ± 0.537
0.762GlnMet: 0.762 ± 0.331
1.269GlnAsn: 1.269 ± 0.827
0.762GlnPro: 0.762 ± 0.191
0.508GlnGln: 0.508 ± 0.317
3.554GlnArg: 3.554 ± 1.075
1.523GlnSer: 1.523 ± 0.382
1.777GlnThr: 1.777 ± 0.409
2.539GlnVal: 2.539 ± 0.697
0.508GlnTrp: 0.508 ± 0.134
1.269GlnTyr: 1.269 ± 0.474
0.0GlnXaa: 0.0 ± 0.0
Arg
2.031ArgAla: 2.031 ± 0.649
0.762ArgCys: 0.762 ± 0.331
4.062ArgAsp: 4.062 ± 1.298
2.285ArgGlu: 2.285 ± 0.573
2.285ArgPhe: 2.285 ± 0.796
1.015ArgGly: 1.015 ± 0.325
1.523ArgHis: 1.523 ± 0.382
2.539ArgIle: 2.539 ± 1.304
3.554ArgLys: 3.554 ± 0.817
5.077ArgLeu: 5.077 ± 1.278
1.015ArgMet: 1.015 ± 0.268
3.808ArgAsn: 3.808 ± 1.156
1.523ArgPro: 1.523 ± 0.591
2.031ArgGln: 2.031 ± 0.472
4.316ArgArg: 4.316 ± 0.123
3.3ArgSer: 3.3 ± 1.41
1.777ArgThr: 1.777 ± 0.409
3.046ArgVal: 3.046 ± 0.356
0.0ArgTrp: 0.0 ± 0.0
2.031ArgTyr: 2.031 ± 0.528
0.0ArgXaa: 0.0 ± 0.0
Ser
2.539SerAla: 2.539 ± 0.661
3.3SerCys: 3.3 ± 0.974
3.3SerAsp: 3.3 ± 1.184
3.3SerGlu: 3.3 ± 0.974
2.793SerPhe: 2.793 ± 1.385
3.3SerGly: 3.3 ± 1.184
0.762SerHis: 0.762 ± 0.191
8.124SerIle: 8.124 ± 2.597
6.601SerLys: 6.601 ± 1.884
6.347SerLeu: 6.347 ± 0.549
2.285SerMet: 2.285 ± 0.796
3.046SerAsn: 3.046 ± 1.015
2.031SerPro: 2.031 ± 1.267
3.554SerGln: 3.554 ± 0.849
2.793SerArg: 2.793 ± 0.832
6.601SerSer: 6.601 ± 0.67
4.57SerThr: 4.57 ± 1.069
4.316SerVal: 4.316 ± 1.038
1.015SerTrp: 1.015 ± 0.788
3.046SerTyr: 3.046 ± 0.261
0.0SerXaa: 0.0 ± 0.0
Thr
3.808ThrAla: 3.808 ± 0.908
2.539ThrCys: 2.539 ± 1.536
1.015ThrAsp: 1.015 ± 0.268
4.316ThrGlu: 4.316 ± 0.253
2.539ThrPhe: 2.539 ± 0.579
3.046ThrGly: 3.046 ± 0.695
0.762ThrHis: 0.762 ± 0.331
4.316ThrIle: 4.316 ± 0.893
4.57ThrLys: 4.57 ± 0.475
4.062ThrLeu: 4.062 ± 2.307
0.762ThrMet: 0.762 ± 0.191
3.3ThrAsn: 3.3 ± 0.794
2.031ThrPro: 2.031 ± 0.535
1.015ThrGln: 1.015 ± 0.325
1.777ThrArg: 1.777 ± 0.509
5.331ThrSer: 5.331 ± 1.374
4.316ThrThr: 4.316 ± 2.411
3.554ThrVal: 3.554 ± 1.162
0.508ThrTrp: 0.508 ± 0.134
5.077ThrTyr: 5.077 ± 0.575
0.0ThrXaa: 0.0 ± 0.0
Val
2.539ValAla: 2.539 ± 1.456
1.523ValCys: 1.523 ± 0.662
2.031ValAsp: 2.031 ± 0.535
3.554ValGlu: 3.554 ± 0.817
2.539ValPhe: 2.539 ± 1.584
2.031ValGly: 2.031 ± 2.41
0.508ValHis: 0.508 ± 0.134
3.808ValIle: 3.808 ± 0.926
4.57ValLys: 4.57 ± 0.475
5.585ValLeu: 5.585 ± 0.752
1.015ValMet: 1.015 ± 0.268
2.793ValAsn: 2.793 ± 0.506
2.285ValPro: 2.285 ± 1.316
2.539ValGln: 2.539 ± 0.579
2.793ValArg: 2.793 ± 0.827
2.285ValSer: 2.285 ± 0.415
3.3ValThr: 3.3 ± 0.308
3.3ValVal: 3.3 ± 2.062
0.508ValTrp: 0.508 ± 0.317
2.539ValTyr: 2.539 ± 0.907
0.0ValXaa: 0.0 ± 0.0
Trp
0.254TrpAla: 0.254 ± 0.222
0.254TrpCys: 0.254 ± 0.222
0.254TrpAsp: 0.254 ± 0.158
0.254TrpGlu: 0.254 ± 0.158
1.777TrpPhe: 1.777 ± 0.509
0.508TrpGly: 0.508 ± 0.445
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.508TrpLys: 0.508 ± 0.823
1.269TrpLeu: 1.269 ± 0.678
0.254TrpMet: 0.254 ± 0.222
0.254TrpAsn: 0.254 ± 0.158
0.0TrpPro: 0.0 ± 0.0
0.762TrpGln: 0.762 ± 0.793
0.0TrpArg: 0.0 ± 0.0
1.523TrpSer: 1.523 ± 0.95
0.508TrpThr: 0.508 ± 0.317
0.762TrpVal: 0.762 ± 0.191
0.0TrpTrp: 0.0 ± 0.0
0.508TrpTyr: 0.508 ± 0.134
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.269TyrAla: 1.269 ± 0.289
0.508TyrCys: 0.508 ± 0.445
3.046TyrAsp: 3.046 ± 0.974
4.316TyrGlu: 4.316 ± 1.215
2.539TyrPhe: 2.539 ± 0.947
1.777TyrGly: 1.777 ± 0.581
1.015TyrHis: 1.015 ± 0.89
3.808TyrIle: 3.808 ± 1.106
3.808TyrLys: 3.808 ± 1.156
2.285TyrLeu: 2.285 ± 0.711
2.031TyrMet: 2.031 ± 1.07
3.3TyrAsn: 3.3 ± 0.637
0.508TyrPro: 0.508 ± 0.134
1.015TyrGln: 1.015 ± 0.548
1.015TyrArg: 1.015 ± 0.325
1.777TyrSer: 1.777 ± 0.509
3.554TyrThr: 3.554 ± 1.077
2.031TyrVal: 2.031 ± 0.939
0.508TyrTrp: 0.508 ± 0.134
0.762TyrTyr: 0.762 ± 0.667
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (3940 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski