Amino acid dipepetide frequency for Paspalum striate mosaic virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.937AlaAla: 3.937 ± 3.941
0.0AlaCys: 0.0 ± 0.0
4.921AlaAsp: 4.921 ± 0.811
8.858AlaGlu: 8.858 ± 1.941
2.953AlaPhe: 2.953 ± 2.148
0.984AlaGly: 0.984 ± 0.954
1.969AlaHis: 1.969 ± 0.761
1.969AlaIle: 1.969 ± 1.508
5.906AlaLys: 5.906 ± 1.572
6.89AlaLeu: 6.89 ± 2.061
0.0AlaMet: 0.0 ± 0.0
1.969AlaAsn: 1.969 ± 1.001
5.906AlaPro: 5.906 ± 0.735
1.969AlaGln: 1.969 ± 0.761
5.906AlaArg: 5.906 ± 1.745
4.921AlaSer: 4.921 ± 3.84
4.921AlaThr: 4.921 ± 1.408
5.906AlaVal: 5.906 ± 3.586
1.969AlaTrp: 1.969 ± 0.761
0.984AlaTyr: 0.984 ± 0.886
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.984CysCys: 0.984 ± 0.954
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
1.969CysPhe: 1.969 ± 0.761
0.984CysGly: 0.984 ± 0.789
0.0CysHis: 0.0 ± 0.0
3.937CysIle: 3.937 ± 1.362
2.953CysLys: 2.953 ± 0.551
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
3.937CysAsn: 3.937 ± 1.359
1.969CysPro: 1.969 ± 0.761
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
1.969CysSer: 1.969 ± 0.761
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
1.969CysTrp: 1.969 ± 1.001
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
7.874AspAla: 7.874 ± 1.319
0.0AspCys: 0.0 ± 0.0
0.984AspAsp: 0.984 ± 0.789
3.937AspGlu: 3.937 ± 1.362
1.969AspPhe: 1.969 ± 1.304
1.969AspGly: 1.969 ± 0.761
0.0AspHis: 0.0 ± 0.0
5.906AspIle: 5.906 ± 1.745
0.984AspLys: 0.984 ± 0.954
2.953AspLeu: 2.953 ± 1.656
0.0AspMet: 0.0 ± 0.0
0.984AspAsn: 0.984 ± 0.954
1.969AspPro: 1.969 ± 0.761
0.984AspGln: 0.984 ± 0.954
0.984AspArg: 0.984 ± 0.789
0.0AspSer: 0.0 ± 0.0
2.953AspThr: 2.953 ± 0.551
1.969AspVal: 1.969 ± 1.02
3.937AspTrp: 3.937 ± 1.975
2.953AspTyr: 2.953 ± 0.551
0.0AspXaa: 0.0 ± 0.0
Glu
6.89GluAla: 6.89 ± 0.887
0.0GluCys: 0.0 ± 0.0
5.906GluAsp: 5.906 ± 1.334
0.984GluGlu: 0.984 ± 0.886
1.969GluPhe: 1.969 ± 0.761
0.0GluGly: 0.0 ± 0.0
0.0GluHis: 0.0 ± 0.0
3.937GluIle: 3.937 ± 1.522
0.0GluLys: 0.0 ± 0.0
1.969GluLeu: 1.969 ± 0.761
0.0GluMet: 0.0 ± 0.0
0.984GluAsn: 0.984 ± 0.954
0.0GluPro: 0.0 ± 0.0
1.969GluGln: 1.969 ± 1.772
1.969GluArg: 1.969 ± 0.761
5.906GluSer: 5.906 ± 1.78
2.953GluThr: 2.953 ± 0.551
6.89GluVal: 6.89 ± 3.774
0.984GluTrp: 0.984 ± 0.954
4.921GluTyr: 4.921 ± 1.547
0.0GluXaa: 0.0 ± 0.0
Phe
2.953PheAla: 2.953 ± 2.674
0.0PheCys: 0.0 ± 0.0
4.921PheAsp: 4.921 ± 0.925
0.984PheGlu: 0.984 ± 0.789
2.953PhePhe: 2.953 ± 1.272
2.953PheGly: 2.953 ± 1.223
1.969PheHis: 1.969 ± 0.761
2.953PheIle: 2.953 ± 3.975
3.937PheLys: 3.937 ± 0.901
4.921PheLeu: 4.921 ± 1.942
0.0PheMet: 0.0 ± 0.0
1.969PheAsn: 1.969 ± 1.001
3.937PhePro: 3.937 ± 1.522
4.921PheGln: 4.921 ± 0.925
0.984PheArg: 0.984 ± 1.325
1.969PheSer: 1.969 ± 0.761
3.937PheThr: 3.937 ± 3.815
1.969PheVal: 1.969 ± 1.001
0.0PheTrp: 0.0 ± 0.0
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
3.937GlyAla: 3.937 ± 0.91
0.0GlyCys: 0.0 ± 0.0
0.0GlyAsp: 0.0 ± 0.0
1.969GlyGlu: 1.969 ± 1.001
0.984GlyPhe: 0.984 ± 1.325
3.937GlyGly: 3.937 ± 1.359
0.0GlyHis: 0.0 ± 0.0
1.969GlyIle: 1.969 ± 1.001
1.969GlyLys: 1.969 ± 1.578
4.921GlyLeu: 4.921 ± 2.669
1.969GlyMet: 1.969 ± 0.761
1.969GlyAsn: 1.969 ± 1.02
0.984GlyPro: 0.984 ± 0.789
2.953GlyGln: 2.953 ± 1.451
3.937GlyArg: 3.937 ± 0.91
8.858GlySer: 8.858 ± 2.088
0.0GlyThr: 0.0 ± 0.0
6.89GlyVal: 6.89 ± 2.088
0.0GlyTrp: 0.0 ± 0.0
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
1.969HisCys: 1.969 ± 0.761
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
0.0HisGly: 0.0 ± 0.0
1.969HisHis: 1.969 ± 0.761
0.0HisIle: 0.0 ± 0.0
1.969HisLys: 1.969 ± 0.761
1.969HisLeu: 1.969 ± 0.761
0.0HisMet: 0.0 ± 0.0
1.969HisAsn: 1.969 ± 0.761
3.937HisPro: 3.937 ± 1.522
0.0HisGln: 0.0 ± 0.0
0.984HisArg: 0.984 ± 0.954
0.984HisSer: 0.984 ± 0.789
0.0HisThr: 0.0 ± 0.0
0.984HisVal: 0.984 ± 0.789
0.0HisTrp: 0.0 ± 0.0
0.984HisTyr: 0.984 ± 0.789
0.0HisXaa: 0.0 ± 0.0
Ile
1.969IleAla: 1.969 ± 2.65
0.984IleCys: 0.984 ± 0.789
2.953IleAsp: 2.953 ± 1.272
0.0IleGlu: 0.0 ± 0.0
0.984IlePhe: 0.984 ± 0.954
1.969IleGly: 1.969 ± 0.761
0.984IleHis: 0.984 ± 0.886
4.921IleIle: 4.921 ± 1.942
7.874IleLys: 7.874 ± 1.319
1.969IleLeu: 1.969 ± 1.001
0.0IleMet: 0.0 ± 0.0
0.984IleAsn: 0.984 ± 0.954
4.921IlePro: 4.921 ± 2.367
2.953IleGln: 2.953 ± 1.272
0.0IleArg: 0.0 ± 0.0
3.937IleSer: 3.937 ± 1.522
4.921IleThr: 4.921 ± 1.408
0.984IleVal: 0.984 ± 1.325
0.0IleTrp: 0.0 ± 0.0
2.953IleTyr: 2.953 ± 1.223
0.0IleXaa: 0.0 ± 0.0
Lys
3.937LysAla: 3.937 ± 1.522
1.969LysCys: 1.969 ± 0.761
6.89LysAsp: 6.89 ± 1.268
3.937LysGlu: 3.937 ± 1.522
2.953LysPhe: 2.953 ± 1.272
2.953LysGly: 2.953 ± 1.789
0.0LysHis: 0.0 ± 0.0
0.0LysIle: 0.0 ± 0.0
11.811LysLys: 11.811 ± 3.41
0.984LysLeu: 0.984 ± 0.886
1.969LysMet: 1.969 ± 0.761
0.0LysAsn: 0.0 ± 0.0
0.984LysPro: 0.984 ± 0.954
0.0LysGln: 0.0 ± 0.0
7.874LysArg: 7.874 ± 3.973
9.843LysSer: 9.843 ± 2.355
1.969LysThr: 1.969 ± 1.304
5.906LysVal: 5.906 ± 2.226
0.984LysTrp: 0.984 ± 0.954
5.906LysTyr: 5.906 ± 1.334
0.0LysXaa: 0.0 ± 0.0
Leu
0.0LeuAla: 0.0 ± 0.0
0.984LeuCys: 0.984 ± 0.954
0.984LeuAsp: 0.984 ± 0.886
1.969LeuGlu: 1.969 ± 0.761
4.921LeuPhe: 4.921 ± 1.547
3.937LeuGly: 3.937 ± 1.359
2.953LeuHis: 2.953 ± 1.272
0.984LeuIle: 0.984 ± 1.325
3.937LeuLys: 3.937 ± 0.91
7.874LeuLeu: 7.874 ± 2.219
0.984LeuMet: 0.984 ± 0.622
0.984LeuAsn: 0.984 ± 0.886
0.984LeuPro: 0.984 ± 0.954
5.906LeuGln: 5.906 ± 1.102
1.969LeuArg: 1.969 ± 0.761
9.843LeuSer: 9.843 ± 3.104
6.89LeuThr: 6.89 ± 0.714
8.858LeuVal: 8.858 ± 2.732
0.0LeuTrp: 0.0 ± 0.0
3.937LeuTyr: 3.937 ± 0.901
0.0LeuXaa: 0.0 ± 0.0
Met
3.937MetAla: 3.937 ± 0.91
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
1.969MetGlu: 1.969 ± 0.761
0.0MetPhe: 0.0 ± 0.0
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.0MetLys: 0.0 ± 0.0
0.0MetLeu: 0.0 ± 0.0
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
3.937MetPro: 3.937 ± 1.522
0.984MetGln: 0.984 ± 0.789
0.0MetArg: 0.0 ± 0.0
2.953MetSer: 2.953 ± 1.451
0.0MetThr: 0.0 ± 0.0
1.969MetVal: 1.969 ± 0.761
0.0MetTrp: 0.0 ± 0.0
0.984MetTyr: 0.984 ± 0.789
0.0MetXaa: 0.0 ± 0.0
Asn
3.937AsnAla: 3.937 ± 2.217
0.0AsnCys: 0.0 ± 0.0
0.0AsnAsp: 0.0 ± 0.0
1.969AsnGlu: 1.969 ± 0.761
0.0AsnPhe: 0.0 ± 0.0
3.937AsnGly: 3.937 ± 1.359
0.0AsnHis: 0.0 ± 0.0
0.984AsnIle: 0.984 ± 0.886
1.969AsnLys: 1.969 ± 0.761
6.89AsnLeu: 6.89 ± 1.842
0.0AsnMet: 0.0 ± 0.0
0.0AsnAsn: 0.0 ± 0.0
2.953AsnPro: 2.953 ± 1.272
1.969AsnGln: 1.969 ± 1.908
0.984AsnArg: 0.984 ± 0.954
1.969AsnSer: 1.969 ± 0.761
0.984AsnThr: 0.984 ± 0.954
2.953AsnVal: 2.953 ± 1.272
0.984AsnTrp: 0.984 ± 0.954
0.984AsnTyr: 0.984 ± 0.789
0.0AsnXaa: 0.0 ± 0.0
Pro
1.969ProAla: 1.969 ± 1.508
1.969ProCys: 1.969 ± 1.578
0.0ProAsp: 0.0 ± 0.0
0.0ProGlu: 0.0 ± 0.0
5.906ProPhe: 5.906 ± 1.334
1.969ProGly: 1.969 ± 0.761
0.0ProHis: 0.0 ± 0.0
1.969ProIle: 1.969 ± 0.761
2.953ProLys: 2.953 ± 1.272
1.969ProLeu: 1.969 ± 1.508
0.0ProMet: 0.0 ± 0.0
1.969ProAsn: 1.969 ± 0.761
5.906ProPro: 5.906 ± 2.445
0.984ProGln: 0.984 ± 1.325
5.906ProArg: 5.906 ± 0.735
12.795ProSer: 12.795 ± 2.21
5.906ProThr: 5.906 ± 1.316
3.937ProVal: 3.937 ± 0.91
0.984ProTrp: 0.984 ± 0.886
2.953ProTyr: 2.953 ± 1.451
0.0ProXaa: 0.0 ± 0.0
Gln
2.953GlnAla: 2.953 ± 0.551
1.969GlnCys: 1.969 ± 0.761
2.953GlnAsp: 2.953 ± 1.223
7.874GlnGlu: 7.874 ± 3.227
4.921GlnPhe: 4.921 ± 1.547
0.0GlnGly: 0.0 ± 0.0
0.984GlnHis: 0.984 ± 0.789
0.0GlnIle: 0.0 ± 0.0
1.969GlnLys: 1.969 ± 1.001
0.0GlnLeu: 0.0 ± 0.0
3.937GlnMet: 3.937 ± 1.02
3.937GlnAsn: 3.937 ± 0.901
1.969GlnPro: 1.969 ± 1.001
3.937GlnGln: 3.937 ± 1.522
0.984GlnArg: 0.984 ± 0.954
2.953GlnSer: 2.953 ± 1.223
0.984GlnThr: 0.984 ± 0.954
0.984GlnVal: 0.984 ± 0.954
0.984GlnTrp: 0.984 ± 0.886
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
2.953ArgAla: 2.953 ± 0.551
0.0ArgCys: 0.0 ± 0.0
2.953ArgAsp: 2.953 ± 0.551
1.969ArgGlu: 1.969 ± 1.508
1.969ArgPhe: 1.969 ± 1.908
4.921ArgGly: 4.921 ± 2.283
0.0ArgHis: 0.0 ± 0.0
0.0ArgIle: 0.0 ± 0.0
6.89ArgLys: 6.89 ± 1.842
4.921ArgLeu: 4.921 ± 1.547
1.969ArgMet: 1.969 ± 0.761
1.969ArgAsn: 1.969 ± 0.761
1.969ArgPro: 1.969 ± 0.761
0.0ArgGln: 0.0 ± 0.0
4.921ArgArg: 4.921 ± 1.903
4.921ArgSer: 4.921 ± 2.061
6.89ArgThr: 6.89 ± 1.933
0.0ArgVal: 0.0 ± 0.0
0.984ArgTrp: 0.984 ± 0.954
1.969ArgTyr: 1.969 ± 1.001
0.0ArgXaa: 0.0 ± 0.0
Ser
10.827SerAla: 10.827 ± 3.601
2.953SerCys: 2.953 ± 0.551
2.953SerAsp: 2.953 ± 1.765
8.858SerGlu: 8.858 ± 3.423
3.937SerPhe: 3.937 ± 1.362
4.921SerGly: 4.921 ± 3.687
3.937SerHis: 3.937 ± 0.901
4.921SerIle: 4.921 ± 1.241
4.921SerLys: 4.921 ± 0.925
9.843SerLeu: 9.843 ± 3.077
1.969SerMet: 1.969 ± 0.761
3.937SerAsn: 3.937 ± 0.901
6.89SerPro: 6.89 ± 1.602
8.858SerGln: 8.858 ± 1.088
0.984SerArg: 0.984 ± 0.886
15.748SerSer: 15.748 ± 3.134
10.827SerThr: 10.827 ± 2.53
4.921SerVal: 4.921 ± 2.702
0.984SerTrp: 0.984 ± 0.789
1.969SerTyr: 1.969 ± 0.761
0.0SerXaa: 0.0 ± 0.0
Thr
7.874ThrAla: 7.874 ± 3.87
0.984ThrCys: 0.984 ± 1.325
2.953ThrAsp: 2.953 ± 1.789
2.953ThrGlu: 2.953 ± 0.551
2.953ThrPhe: 2.953 ± 2.148
2.953ThrGly: 2.953 ± 0.551
1.969ThrHis: 1.969 ± 0.761
0.984ThrIle: 0.984 ± 0.954
3.937ThrLys: 3.937 ± 1.359
0.984ThrLeu: 0.984 ± 0.954
0.0ThrMet: 0.0 ± 0.779
2.953ThrAsn: 2.953 ± 0.551
2.953ThrPro: 2.953 ± 0.551
0.984ThrGln: 0.984 ± 1.325
5.906ThrArg: 5.906 ± 1.132
9.843ThrSer: 9.843 ± 1.47
4.921ThrThr: 4.921 ± 1.438
2.953ThrVal: 2.953 ± 0.551
1.969ThrTrp: 1.969 ± 1.908
5.906ThrTyr: 5.906 ± 1.572
0.0ThrXaa: 0.0 ± 0.0
Val
2.953ValAla: 2.953 ± 0.551
0.984ValCys: 0.984 ± 0.954
2.953ValAsp: 2.953 ± 1.272
0.0ValGlu: 0.0 ± 0.0
4.921ValPhe: 4.921 ± 0.925
4.921ValGly: 4.921 ± 0.811
0.984ValHis: 0.984 ± 0.789
5.906ValIle: 5.906 ± 1.334
1.969ValLys: 1.969 ± 1.908
2.953ValLeu: 2.953 ± 1.498
0.984ValMet: 0.984 ± 1.088
1.969ValAsn: 1.969 ± 1.578
4.921ValPro: 4.921 ± 2.206
3.937ValGln: 3.937 ± 1.085
7.874ValArg: 7.874 ± 1.188
11.811ValSer: 11.811 ± 5.169
2.953ValThr: 2.953 ± 2.674
4.921ValVal: 4.921 ± 1.408
0.0ValTrp: 0.0 ± 0.0
1.969ValTyr: 1.969 ± 1.908
0.0ValXaa: 0.0 ± 0.0
Trp
2.953TrpAla: 2.953 ± 1.272
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
0.984TrpPhe: 0.984 ± 0.789
0.984TrpGly: 0.984 ± 0.954
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
2.953TrpLys: 2.953 ± 1.789
3.937TrpLeu: 3.937 ± 0.901
0.984TrpMet: 0.984 ± 0.886
0.0TrpAsn: 0.0 ± 0.0
1.969TrpPro: 1.969 ± 1.908
0.984TrpGln: 0.984 ± 0.789
0.0TrpArg: 0.0 ± 0.0
0.0TrpSer: 0.0 ± 0.0
1.969TrpThr: 1.969 ± 1.02
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.984TyrAla: 0.984 ± 0.886
4.921TyrCys: 4.921 ± 0.925
0.984TyrAsp: 0.984 ± 0.954
0.0TyrGlu: 0.0 ± 0.0
0.984TyrPhe: 0.984 ± 0.954
2.953TyrGly: 2.953 ± 1.272
0.0TyrHis: 0.0 ± 0.0
4.921TyrIle: 4.921 ± 1.942
1.969TyrLys: 1.969 ± 1.508
2.953TyrLeu: 2.953 ± 0.551
0.984TyrMet: 0.984 ± 0.789
0.984TyrAsn: 0.984 ± 0.789
0.984TyrPro: 0.984 ± 1.325
0.0TyrGln: 0.0 ± 0.0
0.0TyrArg: 0.0 ± 0.0
3.937TyrSer: 3.937 ± 1.522
3.937TyrThr: 3.937 ± 1.359
6.89TyrVal: 6.89 ± 2.867
0.984TyrTrp: 0.984 ± 0.789
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (1017 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski