Amino acid dipepetide frequency for Acinetobacter phage vB_AbaS_TRS1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.947AlaAla: 5.947 ± 1.176
0.861AlaCys: 0.861 ± 0.215
3.208AlaAsp: 3.208 ± 0.442
6.495AlaGlu: 6.495 ± 0.971
3.287AlaPhe: 3.287 ± 0.346
3.913AlaGly: 3.913 ± 0.743
1.174AlaHis: 1.174 ± 0.264
5.478AlaIle: 5.478 ± 0.81
6.573AlaLys: 6.573 ± 0.966
6.886AlaLeu: 6.886 ± 0.999
2.739AlaMet: 2.739 ± 0.533
4.539AlaAsn: 4.539 ± 0.543
1.565AlaPro: 1.565 ± 0.376
3.13AlaGln: 3.13 ± 0.82
3.365AlaArg: 3.365 ± 0.64
5.321AlaSer: 5.321 ± 0.696
5.321AlaThr: 5.321 ± 0.863
4.46AlaVal: 4.46 ± 0.605
1.409AlaTrp: 1.409 ± 0.296
3.13AlaTyr: 3.13 ± 0.512
0.0AlaXaa: 0.0 ± 0.0
Cys
0.861CysAla: 0.861 ± 0.265
0.313CysCys: 0.313 ± 0.144
0.548CysAsp: 0.548 ± 0.237
0.783CysGlu: 0.783 ± 0.222
0.235CysPhe: 0.235 ± 0.161
1.174CysGly: 1.174 ± 0.273
0.157CysHis: 0.157 ± 0.118
0.548CysIle: 0.548 ± 0.211
0.861CysLys: 0.861 ± 0.262
1.174CysLeu: 1.174 ± 0.301
0.704CysMet: 0.704 ± 0.249
0.626CysAsn: 0.626 ± 0.224
0.235CysPro: 0.235 ± 0.137
0.704CysGln: 0.704 ± 0.334
0.391CysArg: 0.391 ± 0.175
0.313CysSer: 0.313 ± 0.161
0.939CysThr: 0.939 ± 0.267
0.704CysVal: 0.704 ± 0.231
0.078CysTrp: 0.078 ± 0.072
0.313CysTyr: 0.313 ± 0.187
0.0CysXaa: 0.0 ± 0.0
Asp
5.086AspAla: 5.086 ± 0.708
0.861AspCys: 0.861 ± 0.266
3.208AspAsp: 3.208 ± 0.592
4.539AspGlu: 4.539 ± 0.764
2.426AspPhe: 2.426 ± 0.386
4.304AspGly: 4.304 ± 0.477
0.783AspHis: 0.783 ± 0.247
4.304AspIle: 4.304 ± 0.689
3.365AspLys: 3.365 ± 0.601
5.399AspLeu: 5.399 ± 0.591
1.487AspMet: 1.487 ± 0.292
2.035AspAsn: 2.035 ± 0.368
2.191AspPro: 2.191 ± 0.434
1.956AspGln: 1.956 ± 0.372
2.035AspArg: 2.035 ± 0.513
3.052AspSer: 3.052 ± 0.482
3.287AspThr: 3.287 ± 0.489
2.739AspVal: 2.739 ± 0.47
1.174AspTrp: 1.174 ± 0.275
2.739AspTyr: 2.739 ± 0.509
0.0AspXaa: 0.0 ± 0.0
Glu
7.669GluAla: 7.669 ± 0.779
0.704GluCys: 0.704 ± 0.243
2.504GluAsp: 2.504 ± 0.494
4.226GluGlu: 4.226 ± 0.6
2.739GluPhe: 2.739 ± 0.493
3.991GluGly: 3.991 ± 0.524
1.33GluHis: 1.33 ± 0.387
4.382GluIle: 4.382 ± 0.557
5.791GluLys: 5.791 ± 0.657
6.26GluLeu: 6.26 ± 0.679
1.722GluMet: 1.722 ± 0.406
3.208GluAsn: 3.208 ± 0.522
1.722GluPro: 1.722 ± 0.412
4.46GluGln: 4.46 ± 0.891
3.521GluArg: 3.521 ± 0.494
4.93GluSer: 4.93 ± 0.685
4.147GluThr: 4.147 ± 0.567
3.913GluVal: 3.913 ± 0.498
1.174GluTrp: 1.174 ± 0.297
3.052GluTyr: 3.052 ± 0.527
0.0GluXaa: 0.0 ± 0.0
Phe
2.504PheAla: 2.504 ± 0.494
0.626PheCys: 0.626 ± 0.223
2.895PheAsp: 2.895 ± 0.384
3.365PheGlu: 3.365 ± 0.554
1.722PhePhe: 1.722 ± 0.482
2.817PheGly: 2.817 ± 0.412
0.783PheHis: 0.783 ± 0.229
3.13PheIle: 3.13 ± 0.619
3.052PheLys: 3.052 ± 0.619
2.974PheLeu: 2.974 ± 0.55
0.626PheMet: 0.626 ± 0.276
2.113PheAsn: 2.113 ± 0.434
1.33PhePro: 1.33 ± 0.398
1.565PheGln: 1.565 ± 0.298
1.252PheArg: 1.252 ± 0.364
2.504PheSer: 2.504 ± 0.454
2.426PheThr: 2.426 ± 0.4
2.661PheVal: 2.661 ± 0.583
0.313PheTrp: 0.313 ± 0.138
1.096PheTyr: 1.096 ± 0.395
0.0PheXaa: 0.0 ± 0.0
Gly
4.773GlyAla: 4.773 ± 0.623
0.626GlyCys: 0.626 ± 0.2
3.208GlyAsp: 3.208 ± 0.541
5.947GlyGlu: 5.947 ± 0.5
3.052GlyPhe: 3.052 ± 0.569
4.617GlyGly: 4.617 ± 0.648
0.861GlyHis: 0.861 ± 0.259
3.13GlyIle: 3.13 ± 0.507
4.617GlyLys: 4.617 ± 0.598
5.165GlyLeu: 5.165 ± 0.531
1.956GlyMet: 1.956 ± 0.448
2.817GlyAsn: 2.817 ± 0.559
0.704GlyPro: 0.704 ± 0.226
2.739GlyGln: 2.739 ± 0.54
2.426GlyArg: 2.426 ± 0.495
4.304GlySer: 4.304 ± 0.786
4.147GlyThr: 4.147 ± 0.678
4.695GlyVal: 4.695 ± 0.668
0.939GlyTrp: 0.939 ± 0.294
2.269GlyTyr: 2.269 ± 0.503
0.0GlyXaa: 0.0 ± 0.0
His
1.722HisAla: 1.722 ± 0.343
0.47HisCys: 0.47 ± 0.191
0.783HisAsp: 0.783 ± 0.275
1.722HisGlu: 1.722 ± 0.396
0.861HisPhe: 0.861 ± 0.255
1.174HisGly: 1.174 ± 0.302
0.313HisHis: 0.313 ± 0.177
1.565HisIle: 1.565 ± 0.416
0.861HisLys: 0.861 ± 0.297
1.643HisLeu: 1.643 ± 0.427
0.157HisMet: 0.157 ± 0.116
0.939HisAsn: 0.939 ± 0.274
1.017HisPro: 1.017 ± 0.317
0.47HisGln: 0.47 ± 0.186
0.783HisArg: 0.783 ± 0.253
1.174HisSer: 1.174 ± 0.355
1.017HisThr: 1.017 ± 0.292
1.017HisVal: 1.017 ± 0.254
0.235HisTrp: 0.235 ± 0.176
0.783HisTyr: 0.783 ± 0.26
0.0HisXaa: 0.0 ± 0.0
Ile
4.93IleAla: 4.93 ± 0.495
0.861IleCys: 0.861 ± 0.212
4.852IleAsp: 4.852 ± 0.642
4.695IleGlu: 4.695 ± 0.514
1.8IlePhe: 1.8 ± 0.462
4.617IleGly: 4.617 ± 0.6
0.939IleHis: 0.939 ± 0.276
3.365IleIle: 3.365 ± 0.605
4.695IleLys: 4.695 ± 0.67
4.147IleLeu: 4.147 ± 0.56
1.017IleMet: 1.017 ± 0.313
5.478IleAsn: 5.478 ± 0.593
1.565IlePro: 1.565 ± 0.352
2.974IleGln: 2.974 ± 0.695
2.348IleArg: 2.348 ± 0.527
3.913IleSer: 3.913 ± 0.668
4.304IleThr: 4.304 ± 0.773
2.895IleVal: 2.895 ± 0.357
0.47IleTrp: 0.47 ± 0.191
2.426IleTyr: 2.426 ± 0.466
0.0IleXaa: 0.0 ± 0.0
Lys
6.652LysAla: 6.652 ± 0.711
1.096LysCys: 1.096 ± 0.478
4.695LysAsp: 4.695 ± 0.483
5.321LysGlu: 5.321 ± 0.566
2.895LysPhe: 2.895 ± 0.442
4.539LysGly: 4.539 ± 0.619
1.956LysHis: 1.956 ± 0.348
3.913LysIle: 3.913 ± 0.488
7.356LysLys: 7.356 ± 1.014
6.339LysLeu: 6.339 ± 0.828
2.191LysMet: 2.191 ± 0.376
2.661LysAsn: 2.661 ± 0.483
2.269LysPro: 2.269 ± 0.415
4.46LysGln: 4.46 ± 0.647
4.226LysArg: 4.226 ± 0.571
3.365LysSer: 3.365 ± 0.668
4.539LysThr: 4.539 ± 0.706
4.304LysVal: 4.304 ± 0.686
0.548LysTrp: 0.548 ± 0.216
2.035LysTyr: 2.035 ± 0.376
0.0LysXaa: 0.0 ± 0.0
Leu
6.965LeuAla: 6.965 ± 0.829
1.017LeuCys: 1.017 ± 0.343
6.26LeuAsp: 6.26 ± 0.7
6.495LeuGlu: 6.495 ± 0.736
2.504LeuPhe: 2.504 ± 0.457
5.321LeuGly: 5.321 ± 0.604
1.8LeuHis: 1.8 ± 0.386
5.634LeuIle: 5.634 ± 0.819
6.886LeuLys: 6.886 ± 0.669
6.182LeuLeu: 6.182 ± 0.692
1.878LeuMet: 1.878 ± 0.359
6.026LeuAsn: 6.026 ± 0.504
2.974LeuPro: 2.974 ± 0.553
3.443LeuGln: 3.443 ± 0.534
3.991LeuArg: 3.991 ± 0.521
5.634LeuSer: 5.634 ± 0.796
5.399LeuThr: 5.399 ± 0.581
4.773LeuVal: 4.773 ± 0.56
0.861LeuTrp: 0.861 ± 0.269
2.113LeuTyr: 2.113 ± 0.284
0.0LeuXaa: 0.0 ± 0.0
Met
2.113MetAla: 2.113 ± 0.484
0.235MetCys: 0.235 ± 0.129
1.252MetAsp: 1.252 ± 0.264
1.096MetGlu: 1.096 ± 0.264
1.174MetPhe: 1.174 ± 0.284
1.8MetGly: 1.8 ± 0.354
0.391MetHis: 0.391 ± 0.213
1.33MetIle: 1.33 ± 0.323
2.348MetLys: 2.348 ± 0.462
1.565MetLeu: 1.565 ± 0.338
0.783MetMet: 0.783 ± 0.32
1.8MetAsn: 1.8 ± 0.417
1.017MetPro: 1.017 ± 0.275
1.017MetGln: 1.017 ± 0.261
1.33MetArg: 1.33 ± 0.265
2.191MetSer: 2.191 ± 0.319
1.565MetThr: 1.565 ± 0.35
1.174MetVal: 1.174 ± 0.404
0.157MetTrp: 0.157 ± 0.117
0.47MetTyr: 0.47 ± 0.188
0.0MetXaa: 0.0 ± 0.0
Asn
4.304AsnAla: 4.304 ± 0.756
0.313AsnCys: 0.313 ± 0.157
2.895AsnAsp: 2.895 ± 0.551
3.913AsnGlu: 3.913 ± 0.508
1.878AsnPhe: 1.878 ± 0.369
3.913AsnGly: 3.913 ± 0.548
1.487AsnHis: 1.487 ± 0.35
2.661AsnIle: 2.661 ± 0.509
4.46AsnLys: 4.46 ± 0.604
4.695AsnLeu: 4.695 ± 0.608
1.565AsnMet: 1.565 ± 0.324
2.035AsnAsn: 2.035 ± 0.476
2.817AsnPro: 2.817 ± 0.615
2.504AsnGln: 2.504 ± 0.448
1.878AsnArg: 1.878 ± 0.332
2.582AsnSer: 2.582 ± 0.521
3.13AsnThr: 3.13 ± 0.506
3.208AsnVal: 3.208 ± 0.398
1.096AsnTrp: 1.096 ± 0.27
2.269AsnTyr: 2.269 ± 0.437
0.0AsnXaa: 0.0 ± 0.0
Pro
1.565ProAla: 1.565 ± 0.299
0.157ProCys: 0.157 ± 0.107
2.504ProAsp: 2.504 ± 0.593
2.191ProGlu: 2.191 ± 0.416
1.487ProPhe: 1.487 ± 0.382
0.157ProGly: 0.157 ± 0.102
0.235ProHis: 0.235 ± 0.154
1.878ProIle: 1.878 ± 0.372
1.252ProLys: 1.252 ± 0.312
2.974ProLeu: 2.974 ± 0.4
0.783ProMet: 0.783 ± 0.214
1.8ProAsn: 1.8 ± 0.515
1.33ProPro: 1.33 ± 0.334
2.113ProGln: 2.113 ± 0.487
1.487ProArg: 1.487 ± 0.369
2.661ProSer: 2.661 ± 0.467
2.895ProThr: 2.895 ± 0.584
2.895ProVal: 2.895 ± 0.46
0.235ProTrp: 0.235 ± 0.133
1.017ProTyr: 1.017 ± 0.293
0.0ProXaa: 0.0 ± 0.0
Gln
4.773GlnAla: 4.773 ± 0.614
0.391GlnCys: 0.391 ± 0.158
2.348GlnAsp: 2.348 ± 0.428
2.817GlnGlu: 2.817 ± 0.648
2.035GlnPhe: 2.035 ± 0.369
3.052GlnGly: 3.052 ± 0.491
0.861GlnHis: 0.861 ± 0.348
3.13GlnIle: 3.13 ± 0.523
3.6GlnLys: 3.6 ± 0.662
3.678GlnLeu: 3.678 ± 0.54
0.626GlnMet: 0.626 ± 0.214
1.8GlnAsn: 1.8 ± 0.389
1.174GlnPro: 1.174 ± 0.263
1.8GlnGln: 1.8 ± 0.356
2.348GlnArg: 2.348 ± 0.403
3.365GlnSer: 3.365 ± 0.515
2.582GlnThr: 2.582 ± 0.419
2.817GlnVal: 2.817 ± 0.478
0.078GlnTrp: 0.078 ± 0.082
1.956GlnTyr: 1.956 ± 0.374
0.0GlnXaa: 0.0 ± 0.0
Arg
3.6ArgAla: 3.6 ± 0.621
0.313ArgCys: 0.313 ± 0.152
2.504ArgAsp: 2.504 ± 0.527
2.582ArgGlu: 2.582 ± 0.556
1.722ArgPhe: 1.722 ± 0.394
2.661ArgGly: 2.661 ± 0.577
0.704ArgHis: 0.704 ± 0.23
3.678ArgIle: 3.678 ± 0.514
2.974ArgLys: 2.974 ± 0.596
5.086ArgLeu: 5.086 ± 0.681
1.017ArgMet: 1.017 ± 0.267
2.426ArgAsn: 2.426 ± 0.443
1.409ArgPro: 1.409 ± 0.418
1.565ArgGln: 1.565 ± 0.313
2.191ArgArg: 2.191 ± 0.452
2.191ArgSer: 2.191 ± 0.428
3.13ArgThr: 3.13 ± 0.516
2.426ArgVal: 2.426 ± 0.354
0.704ArgTrp: 0.704 ± 0.251
2.113ArgTyr: 2.113 ± 0.427
0.0ArgXaa: 0.0 ± 0.0
Ser
3.6SerAla: 3.6 ± 0.558
0.861SerCys: 0.861 ± 0.266
3.365SerAsp: 3.365 ± 0.607
3.443SerGlu: 3.443 ± 0.61
2.974SerPhe: 2.974 ± 0.422
4.539SerGly: 4.539 ± 0.577
1.643SerHis: 1.643 ± 0.355
3.991SerIle: 3.991 ± 0.768
5.478SerLys: 5.478 ± 0.664
5.947SerLeu: 5.947 ± 0.767
1.565SerMet: 1.565 ± 0.315
3.678SerAsn: 3.678 ± 0.535
2.035SerPro: 2.035 ± 0.436
2.191SerGln: 2.191 ± 0.366
2.582SerArg: 2.582 ± 0.38
4.147SerSer: 4.147 ± 0.783
3.443SerThr: 3.443 ± 0.53
4.617SerVal: 4.617 ± 0.803
0.626SerTrp: 0.626 ± 0.2
2.269SerTyr: 2.269 ± 0.522
0.0SerXaa: 0.0 ± 0.0
Thr
4.069ThrAla: 4.069 ± 0.557
0.704ThrCys: 0.704 ± 0.27
3.991ThrAsp: 3.991 ± 0.568
3.834ThrGlu: 3.834 ± 0.507
2.661ThrPhe: 2.661 ± 0.421
3.991ThrGly: 3.991 ± 0.498
1.409ThrHis: 1.409 ± 0.264
3.991ThrIle: 3.991 ± 0.784
3.756ThrLys: 3.756 ± 0.6
5.478ThrLeu: 5.478 ± 0.679
1.33ThrMet: 1.33 ± 0.336
3.756ThrAsn: 3.756 ± 0.549
2.191ThrPro: 2.191 ± 0.453
2.974ThrGln: 2.974 ± 0.467
3.052ThrArg: 3.052 ± 0.479
3.756ThrSer: 3.756 ± 0.72
4.46ThrThr: 4.46 ± 0.581
3.913ThrVal: 3.913 ± 0.682
0.704ThrTrp: 0.704 ± 0.232
2.269ThrTyr: 2.269 ± 0.432
0.0ThrXaa: 0.0 ± 0.0
Val
4.93ValAla: 4.93 ± 0.634
0.548ValCys: 0.548 ± 0.222
3.443ValAsp: 3.443 ± 0.459
4.382ValGlu: 4.382 ± 0.682
2.426ValPhe: 2.426 ± 0.449
3.756ValGly: 3.756 ± 0.593
0.939ValHis: 0.939 ± 0.268
3.991ValIle: 3.991 ± 0.558
3.678ValLys: 3.678 ± 0.58
5.321ValLeu: 5.321 ± 0.665
1.643ValMet: 1.643 ± 0.435
3.521ValAsn: 3.521 ± 0.471
2.269ValPro: 2.269 ± 0.371
2.582ValGln: 2.582 ± 0.463
2.582ValArg: 2.582 ± 0.446
3.6ValSer: 3.6 ± 0.449
3.287ValThr: 3.287 ± 0.754
4.46ValVal: 4.46 ± 0.507
0.783ValTrp: 0.783 ± 0.229
2.895ValTyr: 2.895 ± 0.567
0.0ValXaa: 0.0 ± 0.0
Trp
0.704TrpAla: 0.704 ± 0.227
0.391TrpCys: 0.391 ± 0.203
0.391TrpAsp: 0.391 ± 0.203
0.313TrpGlu: 0.313 ± 0.175
0.391TrpPhe: 0.391 ± 0.17
0.626TrpGly: 0.626 ± 0.194
0.235TrpHis: 0.235 ± 0.134
0.626TrpIle: 0.626 ± 0.24
1.252TrpLys: 1.252 ± 0.316
1.487TrpLeu: 1.487 ± 0.36
0.157TrpMet: 0.157 ± 0.121
0.783TrpAsn: 0.783 ± 0.275
0.235TrpPro: 0.235 ± 0.135
0.626TrpGln: 0.626 ± 0.243
1.017TrpArg: 1.017 ± 0.333
1.33TrpSer: 1.33 ± 0.332
0.704TrpThr: 0.704 ± 0.251
0.704TrpVal: 0.704 ± 0.214
0.157TrpTrp: 0.157 ± 0.118
0.313TrpTyr: 0.313 ± 0.127
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.035TyrAla: 2.035 ± 0.426
0.313TyrCys: 0.313 ± 0.176
2.113TyrAsp: 2.113 ± 0.356
3.365TyrGlu: 3.365 ± 0.658
1.487TyrPhe: 1.487 ± 0.412
2.035TyrGly: 2.035 ± 0.495
0.704TyrHis: 0.704 ± 0.209
1.565TyrIle: 1.565 ± 0.321
2.504TyrLys: 2.504 ± 0.436
3.756TyrLeu: 3.756 ± 0.541
0.783TyrMet: 0.783 ± 0.261
1.565TyrAsn: 1.565 ± 0.316
1.565TyrPro: 1.565 ± 0.423
1.956TyrGln: 1.956 ± 0.37
2.191TyrArg: 2.191 ± 0.379
2.661TyrSer: 2.661 ± 0.527
1.565TyrThr: 1.565 ± 0.396
2.661TyrVal: 2.661 ± 0.413
0.704TyrTrp: 0.704 ± 0.208
1.33TyrTyr: 1.33 ± 0.308
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 70 proteins (12780 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski