Amino acid dipepetide frequency for Sulfitobacter phage phiGT1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
14.981AlaAla: 14.981 ± 1.221
0.946AlaCys: 0.946 ± 0.32
5.992AlaAsp: 5.992 ± 0.854
7.569AlaGlu: 7.569 ± 1.086
3.627AlaPhe: 3.627 ± 0.404
8.515AlaGly: 8.515 ± 1.019
1.735AlaHis: 1.735 ± 0.393
5.992AlaIle: 5.992 ± 0.681
6.15AlaLys: 6.15 ± 0.892
9.777AlaLeu: 9.777 ± 0.786
4.1AlaMet: 4.1 ± 0.77
4.1AlaAsn: 4.1 ± 0.479
4.81AlaPro: 4.81 ± 0.765
4.652AlaGln: 4.652 ± 0.607
6.781AlaArg: 6.781 ± 0.753
6.387AlaSer: 6.387 ± 0.745
7.333AlaThr: 7.333 ± 1.088
6.544AlaVal: 6.544 ± 0.69
2.05AlaTrp: 2.05 ± 0.409
2.76AlaTyr: 2.76 ± 0.499
0.0AlaXaa: 0.0 ± 0.0
Cys
1.262CysAla: 1.262 ± 0.446
0.079CysCys: 0.079 ± 0.073
0.71CysAsp: 0.71 ± 0.212
0.631CysGlu: 0.631 ± 0.212
0.394CysPhe: 0.394 ± 0.171
1.025CysGly: 1.025 ± 0.306
0.631CysHis: 0.631 ± 0.268
0.473CysIle: 0.473 ± 0.206
0.631CysLys: 0.631 ± 0.264
0.552CysLeu: 0.552 ± 0.228
0.158CysMet: 0.158 ± 0.12
0.552CysAsn: 0.552 ± 0.178
0.394CysPro: 0.394 ± 0.192
0.237CysGln: 0.237 ± 0.132
0.71CysArg: 0.71 ± 0.22
0.473CysSer: 0.473 ± 0.173
0.71CysThr: 0.71 ± 0.294
1.183CysVal: 1.183 ± 0.355
0.315CysTrp: 0.315 ± 0.158
0.237CysTyr: 0.237 ± 0.132
0.0CysXaa: 0.0 ± 0.0
Asp
10.25AspAla: 10.25 ± 1.085
1.104AspCys: 1.104 ± 0.318
4.573AspAsp: 4.573 ± 0.715
3.785AspGlu: 3.785 ± 0.812
2.444AspPhe: 2.444 ± 0.431
6.465AspGly: 6.465 ± 0.725
1.104AspHis: 1.104 ± 0.287
2.602AspIle: 2.602 ± 0.364
3.233AspLys: 3.233 ± 0.62
4.652AspLeu: 4.652 ± 0.554
1.656AspMet: 1.656 ± 0.449
2.681AspAsn: 2.681 ± 0.393
2.917AspPro: 2.917 ± 0.524
2.287AspGln: 2.287 ± 0.442
2.681AspArg: 2.681 ± 0.552
2.76AspSer: 2.76 ± 0.415
2.996AspThr: 2.996 ± 0.472
4.652AspVal: 4.652 ± 0.588
1.025AspTrp: 1.025 ± 0.261
2.523AspTyr: 2.523 ± 0.406
0.0AspXaa: 0.0 ± 0.0
Glu
7.727GluAla: 7.727 ± 1.373
0.552GluCys: 0.552 ± 0.239
3.154GluAsp: 3.154 ± 0.556
2.602GluGlu: 2.602 ± 0.526
1.656GluPhe: 1.656 ± 0.363
4.179GluGly: 4.179 ± 0.575
1.025GluHis: 1.025 ± 0.324
2.917GluIle: 2.917 ± 0.545
3.075GluLys: 3.075 ± 0.591
3.39GluLeu: 3.39 ± 0.427
1.971GluMet: 1.971 ± 0.423
2.523GluAsn: 2.523 ± 0.447
1.735GluPro: 1.735 ± 0.399
3.312GluGln: 3.312 ± 0.766
4.258GluArg: 4.258 ± 0.742
2.76GluSer: 2.76 ± 0.393
2.917GluThr: 2.917 ± 0.472
3.627GluVal: 3.627 ± 0.538
1.419GluTrp: 1.419 ± 0.326
1.577GluTyr: 1.577 ± 0.305
0.0GluXaa: 0.0 ± 0.0
Phe
3.075PheAla: 3.075 ± 0.408
0.473PheCys: 0.473 ± 0.201
3.154PheAsp: 3.154 ± 0.614
1.656PheGlu: 1.656 ± 0.343
1.183PhePhe: 1.183 ± 0.258
3.548PheGly: 3.548 ± 0.491
0.71PheHis: 0.71 ± 0.256
1.971PheIle: 1.971 ± 0.508
1.34PheLys: 1.34 ± 0.283
1.813PheLeu: 1.813 ± 0.324
1.104PheMet: 1.104 ± 0.283
1.735PheAsn: 1.735 ± 0.393
1.104PhePro: 1.104 ± 0.286
0.867PheGln: 0.867 ± 0.288
1.971PheArg: 1.971 ± 0.452
2.287PheSer: 2.287 ± 0.397
1.735PheThr: 1.735 ± 0.337
2.129PheVal: 2.129 ± 0.354
0.552PheTrp: 0.552 ± 0.206
1.025PheTyr: 1.025 ± 0.338
0.0PheXaa: 0.0 ± 0.0
Gly
9.225GlyAla: 9.225 ± 1.113
0.946GlyCys: 0.946 ± 0.291
4.1GlyAsp: 4.1 ± 0.553
4.888GlyGlu: 4.888 ± 0.453
3.785GlyPhe: 3.785 ± 0.535
9.935GlyGly: 9.935 ± 1.617
1.813GlyHis: 1.813 ± 0.372
4.573GlyIle: 4.573 ± 0.708
3.942GlyLys: 3.942 ± 0.617
8.042GlyLeu: 8.042 ± 0.962
2.287GlyMet: 2.287 ± 0.453
4.494GlyAsn: 4.494 ± 0.89
3.154GlyPro: 3.154 ± 0.516
4.179GlyGln: 4.179 ± 0.692
4.021GlyArg: 4.021 ± 0.573
5.44GlySer: 5.44 ± 0.77
5.913GlyThr: 5.913 ± 0.854
6.623GlyVal: 6.623 ± 0.706
1.577GlyTrp: 1.577 ± 0.358
2.838GlyTyr: 2.838 ± 0.35
0.0GlyXaa: 0.0 ± 0.0
His
1.104HisAla: 1.104 ± 0.316
0.315HisCys: 0.315 ± 0.19
1.577HisAsp: 1.577 ± 0.415
0.946HisGlu: 0.946 ± 0.274
0.473HisPhe: 0.473 ± 0.186
1.735HisGly: 1.735 ± 0.417
0.473HisHis: 0.473 ± 0.212
1.183HisIle: 1.183 ± 0.358
1.183HisLys: 1.183 ± 0.31
0.867HisLeu: 0.867 ± 0.269
0.394HisMet: 0.394 ± 0.19
0.315HisAsn: 0.315 ± 0.168
0.788HisPro: 0.788 ± 0.295
0.394HisGln: 0.394 ± 0.212
1.735HisArg: 1.735 ± 0.52
0.788HisSer: 0.788 ± 0.308
0.867HisThr: 0.867 ± 0.223
0.946HisVal: 0.946 ± 0.25
0.394HisTrp: 0.394 ± 0.174
0.237HisTyr: 0.237 ± 0.154
0.0HisXaa: 0.0 ± 0.0
Ile
6.623IleAla: 6.623 ± 0.813
0.631IleCys: 0.631 ± 0.206
3.233IleAsp: 3.233 ± 0.451
4.021IleGlu: 4.021 ± 0.695
1.34IlePhe: 1.34 ± 0.347
5.756IleGly: 5.756 ± 0.665
0.552IleHis: 0.552 ± 0.224
1.892IleIle: 1.892 ± 0.4
1.813IleLys: 1.813 ± 0.426
2.602IleLeu: 2.602 ± 0.512
1.025IleMet: 1.025 ± 0.27
1.34IleAsn: 1.34 ± 0.325
1.892IlePro: 1.892 ± 0.406
1.577IleGln: 1.577 ± 0.356
2.681IleArg: 2.681 ± 0.525
3.469IleSer: 3.469 ± 0.49
2.602IleThr: 2.602 ± 0.501
2.838IleVal: 2.838 ± 0.549
1.025IleTrp: 1.025 ± 0.275
1.419IleTyr: 1.419 ± 0.359
0.0IleXaa: 0.0 ± 0.0
Lys
6.387LysAla: 6.387 ± 0.706
0.946LysCys: 0.946 ± 0.268
2.76LysAsp: 2.76 ± 0.46
1.656LysGlu: 1.656 ± 0.398
1.34LysPhe: 1.34 ± 0.362
3.233LysGly: 3.233 ± 0.636
0.788LysHis: 0.788 ± 0.274
1.813LysIle: 1.813 ± 0.344
2.365LysLys: 2.365 ± 0.464
3.233LysLeu: 3.233 ± 0.473
1.813LysMet: 1.813 ± 0.508
2.838LysAsn: 2.838 ± 0.51
3.706LysPro: 3.706 ± 0.677
1.971LysGln: 1.971 ± 0.449
3.312LysArg: 3.312 ± 0.476
2.917LysSer: 2.917 ± 0.527
3.154LysThr: 3.154 ± 0.475
2.996LysVal: 2.996 ± 0.492
0.867LysTrp: 0.867 ± 0.296
1.419LysTyr: 1.419 ± 0.354
0.0LysXaa: 0.0 ± 0.0
Leu
7.806LeuAla: 7.806 ± 0.749
0.71LeuCys: 0.71 ± 0.34
5.913LeuAsp: 5.913 ± 0.7
3.627LeuGlu: 3.627 ± 0.471
2.208LeuPhe: 2.208 ± 0.501
7.175LeuGly: 7.175 ± 1.099
1.104LeuHis: 1.104 ± 0.361
3.39LeuIle: 3.39 ± 0.46
2.838LeuLys: 2.838 ± 0.374
4.021LeuLeu: 4.021 ± 0.62
1.813LeuMet: 1.813 ± 0.368
3.312LeuAsn: 3.312 ± 0.527
3.39LeuPro: 3.39 ± 0.617
2.129LeuGln: 2.129 ± 0.434
6.544LeuArg: 6.544 ± 0.798
4.731LeuSer: 4.731 ± 0.642
4.573LeuThr: 4.573 ± 0.612
4.179LeuVal: 4.179 ± 0.661
0.71LeuTrp: 0.71 ± 0.222
1.656LeuTyr: 1.656 ± 0.367
0.0LeuXaa: 0.0 ± 0.0
Met
3.312MetAla: 3.312 ± 0.522
0.158MetCys: 0.158 ± 0.106
2.129MetAsp: 2.129 ± 0.486
1.183MetGlu: 1.183 ± 0.309
1.34MetPhe: 1.34 ± 0.324
2.838MetGly: 2.838 ± 0.597
0.079MetHis: 0.079 ± 0.079
1.577MetIle: 1.577 ± 0.362
1.262MetLys: 1.262 ± 0.333
1.813MetLeu: 1.813 ± 0.373
0.946MetMet: 0.946 ± 0.395
1.104MetAsn: 1.104 ± 0.291
1.498MetPro: 1.498 ± 0.411
1.892MetGln: 1.892 ± 0.464
2.287MetArg: 2.287 ± 0.4
2.208MetSer: 2.208 ± 0.382
2.208MetThr: 2.208 ± 0.487
1.104MetVal: 1.104 ± 0.374
0.237MetTrp: 0.237 ± 0.134
0.473MetTyr: 0.473 ± 0.211
0.0MetXaa: 0.0 ± 0.0
Asn
4.652AsnAla: 4.652 ± 0.61
0.473AsnCys: 0.473 ± 0.214
2.129AsnAsp: 2.129 ± 0.318
2.365AsnGlu: 2.365 ± 0.446
1.262AsnPhe: 1.262 ± 0.42
4.415AsnGly: 4.415 ± 0.572
0.631AsnHis: 0.631 ± 0.276
1.419AsnIle: 1.419 ± 0.289
1.498AsnLys: 1.498 ± 0.319
3.154AsnLeu: 3.154 ± 0.495
1.183AsnMet: 1.183 ± 0.32
1.813AsnAsn: 1.813 ± 0.489
2.996AsnPro: 2.996 ± 0.411
1.419AsnGln: 1.419 ± 0.368
1.892AsnArg: 1.892 ± 0.323
1.813AsnSer: 1.813 ± 0.399
2.365AsnThr: 2.365 ± 0.55
2.76AsnVal: 2.76 ± 0.557
1.104AsnTrp: 1.104 ± 0.344
0.867AsnTyr: 0.867 ± 0.233
0.0AsnXaa: 0.0 ± 0.0
Pro
4.652ProAla: 4.652 ± 0.67
0.394ProCys: 0.394 ± 0.208
3.469ProAsp: 3.469 ± 0.613
3.233ProGlu: 3.233 ± 0.547
1.419ProPhe: 1.419 ± 0.357
2.838ProGly: 2.838 ± 0.488
1.104ProHis: 1.104 ± 0.284
2.523ProIle: 2.523 ± 0.456
2.05ProLys: 2.05 ± 0.422
3.154ProLeu: 3.154 ± 0.48
1.419ProMet: 1.419 ± 0.308
2.444ProAsn: 2.444 ± 0.463
1.971ProPro: 1.971 ± 0.463
2.05ProGln: 2.05 ± 0.533
1.971ProArg: 1.971 ± 0.414
3.785ProSer: 3.785 ± 0.514
2.523ProThr: 2.523 ± 0.482
2.129ProVal: 2.129 ± 0.458
0.631ProTrp: 0.631 ± 0.226
0.552ProTyr: 0.552 ± 0.186
0.0ProXaa: 0.0 ± 0.0
Gln
5.283GlnAla: 5.283 ± 0.756
0.552GlnCys: 0.552 ± 0.201
2.287GlnAsp: 2.287 ± 0.447
2.681GlnGlu: 2.681 ± 0.498
1.498GlnPhe: 1.498 ± 0.312
3.469GlnGly: 3.469 ± 0.518
0.631GlnHis: 0.631 ± 0.184
2.287GlnIle: 2.287 ± 0.442
1.419GlnLys: 1.419 ± 0.337
3.548GlnLeu: 3.548 ± 0.65
1.656GlnMet: 1.656 ± 0.408
0.946GlnAsn: 0.946 ± 0.303
1.735GlnPro: 1.735 ± 0.393
2.365GlnGln: 2.365 ± 0.496
2.602GlnArg: 2.602 ± 0.507
3.075GlnSer: 3.075 ± 0.499
2.444GlnThr: 2.444 ± 0.414
2.05GlnVal: 2.05 ± 0.474
1.025GlnTrp: 1.025 ± 0.292
0.946GlnTyr: 0.946 ± 0.253
0.0GlnXaa: 0.0 ± 0.0
Arg
6.387ArgAla: 6.387 ± 0.719
0.473ArgCys: 0.473 ± 0.173
5.125ArgAsp: 5.125 ± 0.743
3.706ArgGlu: 3.706 ± 0.676
1.577ArgPhe: 1.577 ± 0.444
4.337ArgGly: 4.337 ± 0.537
1.025ArgHis: 1.025 ± 0.348
3.469ArgIle: 3.469 ± 0.511
4.888ArgLys: 4.888 ± 0.754
4.021ArgLeu: 4.021 ± 0.478
1.498ArgMet: 1.498 ± 0.438
2.602ArgAsn: 2.602 ± 0.491
1.892ArgPro: 1.892 ± 0.354
2.76ArgGln: 2.76 ± 0.579
4.021ArgArg: 4.021 ± 0.868
3.075ArgSer: 3.075 ± 0.447
3.39ArgThr: 3.39 ± 0.473
4.021ArgVal: 4.021 ± 0.587
0.788ArgTrp: 0.788 ± 0.239
1.104ArgTyr: 1.104 ± 0.338
0.0ArgXaa: 0.0 ± 0.0
Ser
5.913SerAla: 5.913 ± 0.991
0.394SerCys: 0.394 ± 0.197
3.785SerAsp: 3.785 ± 0.677
3.154SerGlu: 3.154 ± 0.567
2.208SerPhe: 2.208 ± 0.485
7.096SerGly: 7.096 ± 0.932
0.71SerHis: 0.71 ± 0.238
2.917SerIle: 2.917 ± 0.518
3.706SerLys: 3.706 ± 0.431
4.652SerLeu: 4.652 ± 0.552
1.735SerMet: 1.735 ± 0.435
2.05SerAsn: 2.05 ± 0.443
1.735SerPro: 1.735 ± 0.379
2.681SerGln: 2.681 ± 0.57
3.154SerArg: 3.154 ± 0.629
3.154SerSer: 3.154 ± 0.693
3.154SerThr: 3.154 ± 0.861
3.548SerVal: 3.548 ± 0.456
0.71SerTrp: 0.71 ± 0.216
1.419SerTyr: 1.419 ± 0.371
0.0SerXaa: 0.0 ± 0.0
Thr
6.623ThrAla: 6.623 ± 1.197
0.631ThrCys: 0.631 ± 0.276
4.1ThrAsp: 4.1 ± 0.582
3.154ThrGlu: 3.154 ± 0.432
1.892ThrPhe: 1.892 ± 0.426
7.175ThrGly: 7.175 ± 1.067
0.946ThrHis: 0.946 ± 0.286
2.129ThrIle: 2.129 ± 0.449
2.287ThrLys: 2.287 ± 0.457
4.81ThrLeu: 4.81 ± 0.705
1.577ThrMet: 1.577 ± 0.309
1.735ThrAsn: 1.735 ± 0.504
4.573ThrPro: 4.573 ± 0.532
2.05ThrGln: 2.05 ± 0.411
2.917ThrArg: 2.917 ± 0.45
2.208ThrSer: 2.208 ± 0.488
3.863ThrThr: 3.863 ± 0.717
4.258ThrVal: 4.258 ± 0.632
0.867ThrTrp: 0.867 ± 0.229
1.498ThrTyr: 1.498 ± 0.367
0.0ThrXaa: 0.0 ± 0.0
Val
6.15ValAla: 6.15 ± 0.798
0.867ValCys: 0.867 ± 0.233
4.494ValAsp: 4.494 ± 0.519
2.917ValGlu: 2.917 ± 0.554
2.129ValPhe: 2.129 ± 0.5
4.258ValGly: 4.258 ± 0.502
0.631ValHis: 0.631 ± 0.22
2.681ValIle: 2.681 ± 0.501
3.785ValLys: 3.785 ± 0.484
4.415ValLeu: 4.415 ± 0.73
2.129ValMet: 2.129 ± 0.462
2.208ValAsn: 2.208 ± 0.396
2.602ValPro: 2.602 ± 0.378
3.548ValGln: 3.548 ± 0.462
3.627ValArg: 3.627 ± 0.545
4.337ValSer: 4.337 ± 0.652
4.179ValThr: 4.179 ± 0.675
4.415ValVal: 4.415 ± 0.558
1.813ValTrp: 1.813 ± 0.426
1.262ValTyr: 1.262 ± 0.362
0.0ValXaa: 0.0 ± 0.0
Trp
1.025TrpAla: 1.025 ± 0.275
0.552TrpCys: 0.552 ± 0.18
1.419TrpAsp: 1.419 ± 0.376
1.262TrpGlu: 1.262 ± 0.323
0.473TrpPhe: 0.473 ± 0.2
1.498TrpGly: 1.498 ± 0.404
0.473TrpHis: 0.473 ± 0.2
1.025TrpIle: 1.025 ± 0.277
0.867TrpLys: 0.867 ± 0.242
1.656TrpLeu: 1.656 ± 0.399
0.71TrpMet: 0.71 ± 0.218
0.394TrpAsn: 0.394 ± 0.174
0.473TrpPro: 0.473 ± 0.184
0.946TrpGln: 0.946 ± 0.214
1.735TrpArg: 1.735 ± 0.383
0.946TrpSer: 0.946 ± 0.295
0.867TrpThr: 0.867 ± 0.232
0.71TrpVal: 0.71 ± 0.2
0.237TrpTrp: 0.237 ± 0.134
0.631TrpTyr: 0.631 ± 0.179
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.365TyrAla: 2.365 ± 0.482
0.158TyrCys: 0.158 ± 0.117
2.287TyrAsp: 2.287 ± 0.532
1.34TyrGlu: 1.34 ± 0.38
1.183TyrPhe: 1.183 ± 0.29
2.287TyrGly: 2.287 ± 0.437
0.552TyrHis: 0.552 ± 0.189
1.498TyrIle: 1.498 ± 0.437
1.183TyrLys: 1.183 ± 0.254
1.656TyrLeu: 1.656 ± 0.384
0.394TyrMet: 0.394 ± 0.167
1.025TyrAsn: 1.025 ± 0.282
0.946TyrPro: 0.946 ± 0.297
1.262TyrGln: 1.262 ± 0.373
1.262TyrArg: 1.262 ± 0.35
1.262TyrSer: 1.262 ± 0.309
1.498TyrThr: 1.498 ± 0.396
1.735TyrVal: 1.735 ± 0.426
0.552TyrTrp: 0.552 ± 0.185
0.71TyrTyr: 0.71 ± 0.243
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 69 proteins (12684 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski