Amino acid dipepetide frequency for Rehmannia virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.025AlaAla: 5.025 ± 0.998
2.173AlaCys: 2.173 ± 0.383
4.074AlaAsp: 4.074 ± 0.481
3.667AlaGlu: 3.667 ± 0.446
2.852AlaPhe: 2.852 ± 0.426
2.852AlaGly: 2.852 ± 0.264
0.543AlaHis: 0.543 ± 0.471
4.618AlaIle: 4.618 ± 0.608
2.445AlaLys: 2.445 ± 0.472
6.655AlaLeu: 6.655 ± 0.584
1.494AlaMet: 1.494 ± 0.338
2.716AlaAsn: 2.716 ± 0.833
1.222AlaPro: 1.222 ± 0.244
1.766AlaGln: 1.766 ± 0.319
4.753AlaArg: 4.753 ± 0.42
5.433AlaSer: 5.433 ± 0.572
1.63AlaThr: 1.63 ± 0.214
3.667AlaVal: 3.667 ± 0.77
0.407AlaTrp: 0.407 ± 0.132
1.358AlaTyr: 1.358 ± 0.751
0.0AlaXaa: 0.0 ± 0.0
Cys
0.679CysAla: 0.679 ± 0.428
0.543CysCys: 0.543 ± 0.151
2.173CysAsp: 2.173 ± 0.33
2.445CysGlu: 2.445 ± 0.55
1.901CysPhe: 1.901 ± 0.348
2.173CysGly: 2.173 ± 0.246
0.679CysHis: 0.679 ± 0.195
0.136CysIle: 0.136 ± 0.151
1.766CysLys: 1.766 ± 0.372
2.852CysLeu: 2.852 ± 0.333
0.136CysMet: 0.136 ± 0.205
0.407CysAsn: 0.407 ± 0.321
1.358CysPro: 1.358 ± 0.378
0.136CysGln: 0.136 ± 0.151
2.309CysArg: 2.309 ± 0.573
2.037CysSer: 2.037 ± 0.281
1.222CysThr: 1.222 ± 0.308
1.087CysVal: 1.087 ± 0.16
0.136CysTrp: 0.136 ± 0.163
1.494CysTyr: 1.494 ± 0.316
0.0CysXaa: 0.0 ± 0.0
Asp
3.531AspAla: 3.531 ± 0.438
1.63AspCys: 1.63 ± 0.45
3.395AspAsp: 3.395 ± 0.504
3.531AspGlu: 3.531 ± 0.624
4.074AspPhe: 4.074 ± 0.75
3.803AspGly: 3.803 ± 0.612
1.358AspHis: 1.358 ± 0.324
5.025AspIle: 5.025 ± 0.478
2.852AspLys: 2.852 ± 0.807
7.47AspLeu: 7.47 ± 0.432
1.494AspMet: 1.494 ± 0.401
2.037AspAsn: 2.037 ± 0.403
1.222AspPro: 1.222 ± 0.399
0.136AspGln: 0.136 ± 0.163
3.803AspArg: 3.803 ± 0.306
5.976AspSer: 5.976 ± 0.798
2.58AspThr: 2.58 ± 0.401
5.568AspVal: 5.568 ± 0.612
0.407AspTrp: 0.407 ± 0.136
1.766AspTyr: 1.766 ± 0.537
0.0AspXaa: 0.0 ± 0.0
Glu
1.63GluAla: 1.63 ± 0.152
2.173GluCys: 2.173 ± 0.33
3.124GluAsp: 3.124 ± 1.002
1.901GluGlu: 1.901 ± 0.415
2.309GluPhe: 2.309 ± 0.363
1.494GluGly: 1.494 ± 0.202
0.679GluHis: 0.679 ± 0.433
3.531GluIle: 3.531 ± 0.523
3.803GluLys: 3.803 ± 0.673
7.47GluLeu: 7.47 ± 0.513
1.358GluMet: 1.358 ± 0.147
2.173GluAsn: 2.173 ± 0.233
2.309GluPro: 2.309 ± 0.372
1.358GluGln: 1.358 ± 0.492
4.346GluArg: 4.346 ± 0.478
4.074GluSer: 4.074 ± 0.289
2.445GluThr: 2.445 ± 0.379
4.889GluVal: 4.889 ± 0.61
0.815GluTrp: 0.815 ± 0.227
3.124GluTyr: 3.124 ± 0.267
0.0GluXaa: 0.0 ± 0.0
Phe
3.124PheAla: 3.124 ± 0.375
1.901PheCys: 1.901 ± 0.475
3.531PheAsp: 3.531 ± 0.529
5.161PheGlu: 5.161 ± 0.764
3.939PhePhe: 3.939 ± 0.506
4.074PheGly: 4.074 ± 0.605
1.766PheHis: 1.766 ± 0.283
2.852PheIle: 2.852 ± 1.178
4.074PheLys: 4.074 ± 0.676
4.482PheLeu: 4.482 ± 0.697
0.951PheMet: 0.951 ± 0.19
0.815PheAsn: 0.815 ± 0.189
0.951PhePro: 0.951 ± 0.302
1.087PheGln: 1.087 ± 0.326
2.58PheArg: 2.58 ± 0.401
8.692PheSer: 8.692 ± 1.008
2.309PheThr: 2.309 ± 0.371
5.161PheVal: 5.161 ± 1.1
0.0PheTrp: 0.0 ± 0.0
1.766PheTyr: 1.766 ± 0.276
0.0PheXaa: 0.0 ± 0.0
Gly
4.753GlyAla: 4.753 ± 0.428
1.358GlyCys: 1.358 ± 0.375
4.074GlyAsp: 4.074 ± 0.408
4.482GlyGlu: 4.482 ± 0.596
2.445GlyPhe: 2.445 ± 0.515
5.297GlyGly: 5.297 ± 1.183
1.63GlyHis: 1.63 ± 0.453
1.494GlyIle: 1.494 ± 0.534
4.21GlyLys: 4.21 ± 0.557
2.988GlyLeu: 2.988 ± 0.306
0.407GlyMet: 0.407 ± 0.252
1.901GlyAsn: 1.901 ± 0.407
1.087GlyPro: 1.087 ± 0.302
0.679GlyGln: 0.679 ± 0.147
2.173GlyArg: 2.173 ± 0.258
3.667GlySer: 3.667 ± 0.667
2.716GlyThr: 2.716 ± 0.751
5.704GlyVal: 5.704 ± 1.016
0.407GlyTrp: 0.407 ± 0.277
1.494GlyTyr: 1.494 ± 0.728
0.0GlyXaa: 0.0 ± 0.0
His
1.087HisAla: 1.087 ± 0.334
1.222HisCys: 1.222 ± 0.434
2.173HisAsp: 2.173 ± 0.46
0.951HisGlu: 0.951 ± 0.233
0.679HisPhe: 0.679 ± 0.158
0.951HisGly: 0.951 ± 0.19
0.407HisHis: 0.407 ± 0.137
2.037HisIle: 2.037 ± 0.208
0.543HisLys: 0.543 ± 0.16
2.173HisLeu: 2.173 ± 0.442
0.0HisMet: 0.0 ± 0.0
0.679HisAsn: 0.679 ± 0.168
1.087HisPro: 1.087 ± 0.302
0.679HisGln: 0.679 ± 0.168
0.543HisArg: 0.543 ± 0.278
3.26HisSer: 3.26 ± 0.379
0.815HisThr: 0.815 ± 0.274
1.222HisVal: 1.222 ± 0.332
0.272HisTrp: 0.272 ± 0.076
0.951HisTyr: 0.951 ± 0.26
0.0HisXaa: 0.0 ± 0.0
Ile
3.124IleAla: 3.124 ± 0.756
0.543IleCys: 0.543 ± 0.231
3.395IleAsp: 3.395 ± 0.509
2.852IleGlu: 2.852 ± 0.411
0.815IlePhe: 0.815 ± 0.189
3.803IleGly: 3.803 ± 0.745
1.087IleHis: 1.087 ± 0.321
4.21IleIle: 4.21 ± 0.712
2.445IleLys: 2.445 ± 0.589
3.26IleLeu: 3.26 ± 0.524
1.087IleMet: 1.087 ± 0.383
4.21IleAsn: 4.21 ± 0.658
2.445IlePro: 2.445 ± 0.6
1.087IleGln: 1.087 ± 0.229
4.482IleArg: 4.482 ± 0.562
6.655IleSer: 6.655 ± 0.557
2.445IleThr: 2.445 ± 0.504
5.84IleVal: 5.84 ± 0.859
0.136IleTrp: 0.136 ± 0.163
0.951IleTyr: 0.951 ± 0.191
0.0IleXaa: 0.0 ± 0.0
Lys
3.667LysAla: 3.667 ± 0.449
1.901LysCys: 1.901 ± 0.295
2.852LysAsp: 2.852 ± 0.455
2.173LysGlu: 2.173 ± 0.576
4.21LysPhe: 4.21 ± 0.487
2.173LysGly: 2.173 ± 0.462
1.222LysHis: 1.222 ± 0.275
2.037LysIle: 2.037 ± 0.498
3.124LysLys: 3.124 ± 0.357
7.741LysLeu: 7.741 ± 0.74
1.358LysMet: 1.358 ± 0.237
2.852LysAsn: 2.852 ± 0.327
1.358LysPro: 1.358 ± 0.298
1.087LysGln: 1.087 ± 0.3
4.618LysArg: 4.618 ± 0.474
3.531LysSer: 3.531 ± 0.554
2.716LysThr: 2.716 ± 0.624
4.482LysVal: 4.482 ± 0.355
0.272LysTrp: 0.272 ± 0.227
2.173LysTyr: 2.173 ± 0.694
0.0LysXaa: 0.0 ± 0.0
Leu
6.383LeuAla: 6.383 ± 0.648
2.173LeuCys: 2.173 ± 0.257
6.383LeuAsp: 6.383 ± 0.281
4.618LeuGlu: 4.618 ± 0.502
5.976LeuPhe: 5.976 ± 0.961
3.803LeuGly: 3.803 ± 1.013
1.358LeuHis: 1.358 ± 0.191
4.21LeuIle: 4.21 ± 0.614
5.297LeuLys: 5.297 ± 0.494
10.594LeuLeu: 10.594 ± 0.745
3.124LeuMet: 3.124 ± 0.374
4.889LeuAsn: 4.889 ± 1.494
5.704LeuPro: 5.704 ± 0.482
0.815LeuGln: 0.815 ± 0.321
6.655LeuArg: 6.655 ± 0.634
10.186LeuSer: 10.186 ± 0.596
5.161LeuThr: 5.161 ± 0.661
6.519LeuVal: 6.519 ± 1.242
0.815LeuTrp: 0.815 ± 0.172
3.803LeuTyr: 3.803 ± 0.419
0.0LeuXaa: 0.0 ± 0.0
Met
1.494MetAla: 1.494 ± 0.424
0.679MetCys: 0.679 ± 0.289
0.951MetAsp: 0.951 ± 0.238
0.543MetGlu: 0.543 ± 0.16
1.222MetPhe: 1.222 ± 0.226
0.815MetGly: 0.815 ± 0.274
0.679MetHis: 0.679 ± 0.162
2.037MetIle: 2.037 ± 0.416
0.543MetLys: 0.543 ± 0.294
2.037MetLeu: 2.037 ± 0.251
1.087MetMet: 1.087 ± 0.178
1.222MetAsn: 1.222 ± 0.277
0.543MetPro: 0.543 ± 0.265
0.543MetGln: 0.543 ± 0.155
0.951MetArg: 0.951 ± 0.191
0.815MetSer: 0.815 ± 0.177
1.494MetThr: 1.494 ± 0.25
2.852MetVal: 2.852 ± 0.441
0.0MetTrp: 0.0 ± 0.0
0.543MetTyr: 0.543 ± 0.22
0.0MetXaa: 0.0 ± 0.0
Asn
1.63AsnAla: 1.63 ± 0.403
0.815AsnCys: 0.815 ± 0.242
1.63AsnAsp: 1.63 ± 0.571
2.852AsnGlu: 2.852 ± 0.339
3.531AsnPhe: 3.531 ± 0.407
0.951AsnGly: 0.951 ± 0.208
1.766AsnHis: 1.766 ± 0.478
1.766AsnIle: 1.766 ± 0.486
1.901AsnLys: 1.901 ± 0.697
3.395AsnLeu: 3.395 ± 0.779
0.543AsnMet: 0.543 ± 0.213
1.222AsnAsn: 1.222 ± 0.452
1.63AsnPro: 1.63 ± 0.679
0.679AsnGln: 0.679 ± 0.192
3.26AsnArg: 3.26 ± 0.336
4.346AsnSer: 4.346 ± 0.426
2.309AsnThr: 2.309 ± 0.464
3.124AsnVal: 3.124 ± 0.852
0.0AsnTrp: 0.0 ± 0.0
0.951AsnTyr: 0.951 ± 0.261
0.0AsnXaa: 0.0 ± 0.0
Pro
2.445ProAla: 2.445 ± 0.406
0.407ProCys: 0.407 ± 0.132
1.766ProAsp: 1.766 ± 0.281
1.358ProGlu: 1.358 ± 0.22
3.26ProPhe: 3.26 ± 0.49
1.766ProGly: 1.766 ± 0.361
0.815ProHis: 0.815 ± 0.317
1.901ProIle: 1.901 ± 0.33
1.901ProLys: 1.901 ± 0.411
4.346ProLeu: 4.346 ± 0.617
0.543ProMet: 0.543 ± 0.151
0.951ProAsn: 0.951 ± 0.189
0.951ProPro: 0.951 ± 0.274
0.951ProGln: 0.951 ± 0.267
1.63ProArg: 1.63 ± 0.266
3.667ProSer: 3.667 ± 0.398
1.494ProThr: 1.494 ± 0.249
2.716ProVal: 2.716 ± 0.435
0.543ProTrp: 0.543 ± 0.151
1.63ProTyr: 1.63 ± 0.285
0.0ProXaa: 0.0 ± 0.0
Gln
1.222GlnAla: 1.222 ± 0.654
0.272GlnCys: 0.272 ± 0.076
1.358GlnAsp: 1.358 ± 0.23
1.358GlnGlu: 1.358 ± 0.274
1.222GlnPhe: 1.222 ± 0.25
0.951GlnGly: 0.951 ± 0.213
0.136GlnHis: 0.136 ± 0.205
0.679GlnIle: 0.679 ± 0.358
0.407GlnLys: 0.407 ± 0.132
2.309GlnLeu: 2.309 ± 0.489
0.679GlnMet: 0.679 ± 0.227
0.543GlnAsn: 0.543 ± 0.16
0.543GlnPro: 0.543 ± 0.151
1.358GlnGln: 1.358 ± 0.461
1.358GlnArg: 1.358 ± 0.299
1.63GlnSer: 1.63 ± 0.661
1.222GlnThr: 1.222 ± 0.571
0.679GlnVal: 0.679 ± 0.147
0.136GlnTrp: 0.136 ± 0.163
0.679GlnTyr: 0.679 ± 0.372
0.0GlnXaa: 0.0 ± 0.0
Arg
3.667ArgAla: 3.667 ± 1.1
2.309ArgCys: 2.309 ± 0.354
3.803ArgAsp: 3.803 ± 0.731
4.618ArgGlu: 4.618 ± 0.491
3.395ArgPhe: 3.395 ± 0.401
3.939ArgGly: 3.939 ± 0.278
1.087ArgHis: 1.087 ± 0.198
3.26ArgIle: 3.26 ± 0.464
4.21ArgLys: 4.21 ± 0.374
3.803ArgLeu: 3.803 ± 0.725
1.766ArgMet: 1.766 ± 0.217
2.037ArgAsn: 2.037 ± 0.411
1.63ArgPro: 1.63 ± 0.265
1.358ArgGln: 1.358 ± 0.295
5.025ArgArg: 5.025 ± 0.92
7.47ArgSer: 7.47 ± 0.57
3.124ArgThr: 3.124 ± 0.501
10.186ArgVal: 10.186 ± 1.861
0.136ArgTrp: 0.136 ± 0.151
0.679ArgTyr: 0.679 ± 0.209
0.0ArgXaa: 0.0 ± 0.0
Ser
7.47SerAla: 7.47 ± 1.013
1.901SerCys: 1.901 ± 0.344
4.074SerAsp: 4.074 ± 0.521
5.025SerGlu: 5.025 ± 0.526
6.791SerPhe: 6.791 ± 0.649
5.161SerGly: 5.161 ± 0.42
1.358SerHis: 1.358 ± 0.23
3.939SerIle: 3.939 ± 0.848
7.334SerLys: 7.334 ± 1.144
9.643SerLeu: 9.643 ± 0.763
1.222SerMet: 1.222 ± 0.188
3.395SerAsn: 3.395 ± 0.611
3.26SerPro: 3.26 ± 0.507
2.852SerGln: 2.852 ± 0.418
7.334SerArg: 7.334 ± 0.533
11.544SerSer: 11.544 ± 0.917
5.704SerThr: 5.704 ± 0.803
7.334SerVal: 7.334 ± 0.676
0.0SerTrp: 0.0 ± 0.0
5.433SerTyr: 5.433 ± 0.748
0.0SerXaa: 0.0 ± 0.0
Thr
2.716ThrAla: 2.716 ± 0.379
1.087ThrCys: 1.087 ± 0.225
2.173ThrAsp: 2.173 ± 0.651
2.309ThrGlu: 2.309 ± 0.975
4.482ThrPhe: 4.482 ± 0.635
1.766ThrGly: 1.766 ± 0.528
1.087ThrHis: 1.087 ± 0.302
3.939ThrIle: 3.939 ± 0.505
2.037ThrLys: 2.037 ± 0.568
3.667ThrLeu: 3.667 ± 0.791
2.037ThrMet: 2.037 ± 0.44
1.222ThrAsn: 1.222 ± 0.699
3.124ThrPro: 3.124 ± 0.513
0.272ThrGln: 0.272 ± 0.076
3.26ThrArg: 3.26 ± 0.451
4.21ThrSer: 4.21 ± 1.053
2.309ThrThr: 2.309 ± 0.572
3.395ThrVal: 3.395 ± 0.388
0.407ThrTrp: 0.407 ± 0.132
1.494ThrTyr: 1.494 ± 0.21
0.0ThrXaa: 0.0 ± 0.0
Val
3.939ValAla: 3.939 ± 0.447
2.445ValCys: 2.445 ± 0.413
6.927ValAsp: 6.927 ± 0.529
3.395ValGlu: 3.395 ± 0.503
3.803ValPhe: 3.803 ± 0.515
4.346ValGly: 4.346 ± 0.53
2.58ValHis: 2.58 ± 0.421
4.753ValIle: 4.753 ± 0.711
4.618ValLys: 4.618 ± 0.557
6.247ValLeu: 6.247 ± 0.962
0.815ValMet: 0.815 ± 0.228
3.531ValAsn: 3.531 ± 1.004
3.803ValPro: 3.803 ± 0.439
1.494ValGln: 1.494 ± 0.316
5.976ValArg: 5.976 ± 0.873
9.914ValSer: 9.914 ± 0.828
3.803ValThr: 3.803 ± 0.421
7.334ValVal: 7.334 ± 0.752
0.407ValTrp: 0.407 ± 0.193
4.482ValTyr: 4.482 ± 0.469
0.0ValXaa: 0.0 ± 0.0
Trp
0.272TrpAla: 0.272 ± 0.076
0.136TrpCys: 0.136 ± 0.163
0.407TrpAsp: 0.407 ± 0.171
0.0TrpGlu: 0.0 ± 0.0
0.407TrpPhe: 0.407 ± 0.136
0.272TrpGly: 0.272 ± 0.076
0.0TrpHis: 0.0 ± 0.0
0.815TrpIle: 0.815 ± 0.283
0.272TrpLys: 0.272 ± 0.291
0.679TrpLeu: 0.679 ± 0.147
0.407TrpMet: 0.407 ± 0.289
0.272TrpAsn: 0.272 ± 0.076
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.272TrpArg: 0.272 ± 0.076
0.407TrpSer: 0.407 ± 0.136
0.272TrpThr: 0.272 ± 0.076
0.272TrpVal: 0.272 ± 0.279
0.0TrpTrp: 0.0 ± 0.0
0.272TrpTyr: 0.272 ± 0.076
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.494TyrAla: 1.494 ± 0.223
0.0TyrCys: 0.0 ± 0.0
3.395TyrAsp: 3.395 ± 0.489
1.766TyrGlu: 1.766 ± 0.328
1.901TyrPhe: 1.901 ± 0.329
2.58TyrGly: 2.58 ± 0.346
1.494TyrHis: 1.494 ± 0.25
1.63TyrIle: 1.63 ± 0.295
1.766TyrLys: 1.766 ± 0.588
6.655TyrLeu: 6.655 ± 0.688
0.407TyrMet: 0.407 ± 0.193
1.222TyrAsn: 1.222 ± 0.295
0.815TyrPro: 0.815 ± 0.227
0.407TyrGln: 0.407 ± 0.315
2.173TyrArg: 2.173 ± 0.439
3.26TyrSer: 3.26 ± 0.808
1.222TyrThr: 1.222 ± 0.3
2.716TyrVal: 2.716 ± 0.218
0.136TyrTrp: 0.136 ± 0.205
2.037TyrTyr: 2.037 ± 0.394
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 9 proteins (7364 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski