Amino acid dipepetide frequency for Coprococcus catus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.203AlaAla: 8.203 ± 0.123	1.209AlaCys: 1.209 ± 0.037	5.151AlaAsp: 5.151 ± 0.085	5.721AlaGlu: 5.721 ± 0.1	3.155AlaPhe: 3.155 ± 0.054	6.234AlaGly: 6.234 ± 0.094	1.251AlaHis: 1.251 ± 0.036	5.551AlaIle: 5.551 ± 0.092	4.605AlaLys: 4.605 ± 0.069	7.12AlaLeu: 7.12 ± 0.092	2.654AlaMet: 2.654 ± 0.05	2.673AlaAsn: 2.673 ± 0.058	1.997AlaPro: 1.997 ± 0.047	2.361AlaGln: 2.361 ± 0.057	3.071AlaArg: 3.071 ± 0.057	4.338AlaSer: 4.338 ± 0.07	3.175AlaThr: 3.175 ± 0.063	6.608AlaVal: 6.608 ± 0.086	0.689AlaTrp: 0.689 ± 0.025	2.958AlaTyr: 2.958 ± 0.054	0.0AlaXaa: 0.0 ± 0.0
Cys	1.013CysAla: 1.013 ± 0.031	0.301CysCys: 0.301 ± 0.021	0.891CysAsp: 0.891 ± 0.032	0.896CysGlu: 0.896 ± 0.033	0.631CysPhe: 0.631 ± 0.026	1.515CysGly: 1.515 ± 0.045	0.387CysHis: 0.387 ± 0.022	1.096CysIle: 1.096 ± 0.035	0.761CysLys: 0.761 ± 0.031	1.289CysLeu: 1.289 ± 0.038	0.523CysMet: 0.523 ± 0.022	0.548CysAsn: 0.548 ± 0.025	0.686CysPro: 0.686 ± 0.033	0.499CysGln: 0.499 ± 0.019	0.78CysArg: 0.78 ± 0.029	0.918CysSer: 0.918 ± 0.032	0.78CysThr: 0.78 ± 0.029	1.035CysVal: 1.035 ± 0.038	0.103CysTrp: 0.103 ± 0.01	0.571CysTyr: 0.571 ± 0.024	0.0CysXaa: 0.0 ± 0.0
Asp	4.735AspAla: 4.735 ± 0.076	0.837AspCys: 0.837 ± 0.031	3.39AspAsp: 3.39 ± 0.075	4.774AspGlu: 4.774 ± 0.084	2.617AspPhe: 2.617 ± 0.058	4.499AspGly: 4.499 ± 0.087	1.065AspHis: 1.065 ± 0.04	4.878AspIle: 4.878 ± 0.072	3.635AspLys: 3.635 ± 0.063	4.62AspLeu: 4.62 ± 0.075	2.056AspMet: 2.056 ± 0.048	2.299AspAsn: 2.299 ± 0.054	1.753AspPro: 1.753 ± 0.043	1.595AspGln: 1.595 ± 0.043	2.589AspArg: 2.589 ± 0.052	3.077AspSer: 3.077 ± 0.06	3.191AspThr: 3.191 ± 0.058	4.06AspVal: 4.06 ± 0.078	0.544AspTrp: 0.544 ± 0.023	3.022AspTyr: 3.022 ± 0.064	0.0AspXaa: 0.0 ± 0.0
Glu	5.802GluAla: 5.802 ± 0.093	0.837GluCys: 0.837 ± 0.027	4.381GluAsp: 4.381 ± 0.073	6.137GluGlu: 6.137 ± 0.112	2.172GluPhe: 2.172 ± 0.047	4.201GluGly: 4.201 ± 0.068	1.511GluHis: 1.511 ± 0.044	5.274GluIle: 5.274 ± 0.079	6.253GluLys: 6.253 ± 0.088	6.287GluLeu: 6.287 ± 0.092	2.603GluMet: 2.603 ± 0.056	3.969GluAsn: 3.969 ± 0.069	1.863GluPro: 1.863 ± 0.048	3.089GluGln: 3.089 ± 0.066	3.275GluArg: 3.275 ± 0.075	3.303GluSer: 3.303 ± 0.068	4.009GluThr: 4.009 ± 0.074	4.315GluVal: 4.315 ± 0.068	0.648GluTrp: 0.648 ± 0.029	2.761GluTyr: 2.761 ± 0.055	0.0GluXaa: 0.0 ± 0.0
Phe	2.889PheAla: 2.889 ± 0.06	0.773PheCys: 0.773 ± 0.026	2.551PheAsp: 2.551 ± 0.056	2.587PheGlu: 2.587 ± 0.056	1.611PhePhe: 1.611 ± 0.046	2.992PheGly: 2.992 ± 0.059	0.814PheHis: 0.814 ± 0.031	2.817PheIle: 2.817 ± 0.062	2.115PheLys: 2.115 ± 0.046	3.464PheLeu: 3.464 ± 0.069	1.172PheMet: 1.172 ± 0.038	1.582PheAsn: 1.582 ± 0.048	1.252PhePro: 1.252 ± 0.033	1.178PheGln: 1.178 ± 0.038	1.632PheArg: 1.632 ± 0.047	2.633PheSer: 2.633 ± 0.058	2.136PheThr: 2.136 ± 0.049	2.697PheVal: 2.697 ± 0.052	0.383PheTrp: 0.383 ± 0.021	1.641PheTyr: 1.641 ± 0.048	0.0PheXaa: 0.0 ± 0.0
Gly	5.026GlyAla: 5.026 ± 0.085	1.321GlyCys: 1.321 ± 0.04	3.558GlyAsp: 3.558 ± 0.069	4.437GlyGlu: 4.437 ± 0.074	2.938GlyPhe: 2.938 ± 0.051	4.909GlyGly: 4.909 ± 0.11	1.516GlyHis: 1.516 ± 0.045	5.969GlyIle: 5.969 ± 0.084	5.064GlyLys: 5.064 ± 0.071	5.911GlyLeu: 5.911 ± 0.078	2.577GlyMet: 2.577 ± 0.061	2.919GlyAsn: 2.919 ± 0.057	1.312GlyPro: 1.312 ± 0.041	2.386GlyGln: 2.386 ± 0.06	3.345GlyArg: 3.345 ± 0.059	4.062GlySer: 4.062 ± 0.075	4.184GlyThr: 4.184 ± 0.077	4.865GlyVal: 4.865 ± 0.083	0.687GlyTrp: 0.687 ± 0.027	3.238GlyTyr: 3.238 ± 0.063	0.0GlyXaa: 0.0 ± 0.0
His	1.254HisAla: 1.254 ± 0.039	0.322HisCys: 0.322 ± 0.02	1.003HisAsp: 1.003 ± 0.037	1.264HisGlu: 1.264 ± 0.039	0.884HisPhe: 0.884 ± 0.031	1.389HisGly: 1.389 ± 0.039	0.569HisHis: 0.569 ± 0.036	1.612HisIle: 1.612 ± 0.042	0.914HisLys: 0.914 ± 0.032	1.779HisLeu: 1.779 ± 0.05	0.68HisMet: 0.68 ± 0.028	0.731HisAsn: 0.731 ± 0.029	1.015HisPro: 1.015 ± 0.037	0.767HisGln: 0.767 ± 0.033	0.92HisArg: 0.92 ± 0.034	1.015HisSer: 1.015 ± 0.032	1.064HisThr: 1.064 ± 0.029	1.299HisVal: 1.299 ± 0.042	0.169HisTrp: 0.169 ± 0.014	0.9HisTyr: 0.9 ± 0.029	0.0HisXaa: 0.0 ± 0.0
Ile	5.961IleAla: 5.961 ± 0.089	1.411IleCys: 1.411 ± 0.038	4.164IleAsp: 4.164 ± 0.059	4.846IleGlu: 4.846 ± 0.079	2.927IlePhe: 2.927 ± 0.059	5.3IleGly: 5.3 ± 0.084	1.556IleHis: 1.556 ± 0.041	5.341IleIle: 5.341 ± 0.1	3.89IleLys: 3.89 ± 0.073	6.913IleLeu: 6.913 ± 0.111	2.123IleMet: 2.123 ± 0.049	2.816IleAsn: 2.816 ± 0.054	2.911IlePro: 2.911 ± 0.054	2.529IleGln: 2.529 ± 0.055	3.788IleArg: 3.788 ± 0.07	4.669IleSer: 4.669 ± 0.077	4.029IleThr: 4.029 ± 0.067	5.143IleVal: 5.143 ± 0.083	0.622IleTrp: 0.622 ± 0.026	2.862IleTyr: 2.862 ± 0.052	0.0IleXaa: 0.0 ± 0.0
Lys	5.464LysAla: 5.464 ± 0.08	0.727LysCys: 0.727 ± 0.032	3.898LysAsp: 3.898 ± 0.063	5.634LysGlu: 5.634 ± 0.081	1.695LysPhe: 1.695 ± 0.04	4.081LysGly: 4.081 ± 0.067	1.067LysHis: 1.067 ± 0.034	4.421LysIle: 4.421 ± 0.073	5.6LysLys: 5.6 ± 0.076	5.153LysLeu: 5.153 ± 0.07	2.353LysMet: 2.353 ± 0.048	3.329LysAsn: 3.329 ± 0.058	2.001LysPro: 2.001 ± 0.054	2.422LysGln: 2.422 ± 0.054	2.918LysArg: 2.918 ± 0.058	3.36LysSer: 3.36 ± 0.061	3.592LysThr: 3.592 ± 0.061	4.196LysVal: 4.196 ± 0.08	0.549LysTrp: 0.549 ± 0.025	2.735LysTyr: 2.735 ± 0.052	0.0LysXaa: 0.0 ± 0.0
Leu	6.737LeuAla: 6.737 ± 0.079	1.501LeuCys: 1.501 ± 0.032	5.102LeuAsp: 5.102 ± 0.078	5.717LeuGlu: 5.717 ± 0.083	3.657LeuPhe: 3.657 ± 0.075	5.723LeuGly: 5.723 ± 0.09	1.66LeuHis: 1.66 ± 0.048	6.171LeuIle: 6.171 ± 0.092	6.083LeuLys: 6.083 ± 0.077	8.42LeuLeu: 8.42 ± 0.121	2.952LeuMet: 2.952 ± 0.059	3.921LeuAsn: 3.921 ± 0.056	3.519LeuPro: 3.519 ± 0.063	2.85LeuGln: 2.85 ± 0.056	3.625LeuArg: 3.625 ± 0.064	6.221LeuSer: 6.221 ± 0.081	5.254LeuThr: 5.254 ± 0.08	5.394LeuVal: 5.394 ± 0.08	0.705LeuTrp: 0.705 ± 0.03	3.153LeuTyr: 3.153 ± 0.068	0.0LeuXaa: 0.0 ± 0.0
Met	2.865MetAla: 2.865 ± 0.05	0.406MetCys: 0.406 ± 0.024	2.116MetAsp: 2.116 ± 0.047	2.315MetGlu: 2.315 ± 0.053	0.97MetPhe: 0.97 ± 0.036	2.13MetGly: 2.13 ± 0.048	0.607MetHis: 0.607 ± 0.023	2.426MetIle: 2.426 ± 0.055	2.582MetLys: 2.582 ± 0.051	2.867MetLeu: 2.867 ± 0.056	1.187MetMet: 1.187 ± 0.039	1.761MetAsn: 1.761 ± 0.044	1.344MetPro: 1.344 ± 0.041	1.287MetGln: 1.287 ± 0.035	1.385MetArg: 1.385 ± 0.033	1.992MetSer: 1.992 ± 0.053	2.069MetThr: 2.069 ± 0.046	1.991MetVal: 1.991 ± 0.047	0.22MetTrp: 0.22 ± 0.016	0.969MetTyr: 0.969 ± 0.034	0.0MetXaa: 0.0 ± 0.0
Asn	3.186AsnAla: 3.186 ± 0.056	0.599AsnCys: 0.599 ± 0.024	2.24AsnAsp: 2.24 ± 0.051	2.782AsnGlu: 2.782 ± 0.052	1.529AsnPhe: 1.529 ± 0.041	3.465AsnGly: 3.465 ± 0.075	0.891AsnHis: 0.891 ± 0.028	3.382AsnIle: 3.382 ± 0.065	2.435AsnLys: 2.435 ± 0.05	3.645AsnLeu: 3.645 ± 0.06	1.412AsnMet: 1.412 ± 0.036	1.782AsnAsn: 1.782 ± 0.052	1.898AsnPro: 1.898 ± 0.051	1.54AsnGln: 1.54 ± 0.039	2.134AsnArg: 2.134 ± 0.076	2.197AsnSer: 2.197 ± 0.054	2.273AsnThr: 2.273 ± 0.056	2.888AsnVal: 2.888 ± 0.054	0.404AsnTrp: 0.404 ± 0.021	1.764AsnTyr: 1.764 ± 0.045	0.0AsnXaa: 0.0 ± 0.0
Pro	2.381ProAla: 2.381 ± 0.053	0.4ProCys: 0.4 ± 0.02	2.389ProAsp: 2.389 ± 0.054	3.395ProGlu: 3.395 ± 0.066	1.521ProPhe: 1.521 ± 0.041	2.348ProGly: 2.348 ± 0.051	0.612ProHis: 0.612 ± 0.029	2.116ProIle: 2.116 ± 0.047	1.878ProLys: 1.878 ± 0.048	2.607ProLeu: 2.607 ± 0.054	0.989ProMet: 0.989 ± 0.032	1.2ProAsn: 1.2 ± 0.038	0.739ProPro: 0.739 ± 0.032	1.025ProGln: 1.025 ± 0.033	0.988ProArg: 0.988 ± 0.034	1.77ProSer: 1.77 ± 0.047	1.663ProThr: 1.663 ± 0.045	2.975ProVal: 2.975 ± 0.047	0.305ProTrp: 0.305 ± 0.017	1.423ProTyr: 1.423 ± 0.039	0.0ProXaa: 0.0 ± 0.0
Gln	2.724GlnAla: 2.724 ± 0.057	0.392GlnCys: 0.392 ± 0.019	1.621GlnAsp: 1.621 ± 0.047	2.46GlnGlu: 2.46 ± 0.056	1.203GlnPhe: 1.203 ± 0.032	1.752GlnGly: 1.752 ± 0.041	0.641GlnHis: 0.641 ± 0.026	2.68GlnIle: 2.68 ± 0.061	2.716GlnLys: 2.716 ± 0.055	3.316GlnLeu: 3.316 ± 0.07	1.466GlnMet: 1.466 ± 0.038	1.585GlnAsn: 1.585 ± 0.048	1.062GlnPro: 1.062 ± 0.032	1.443GlnGln: 1.443 ± 0.039	1.551GlnArg: 1.551 ± 0.047	1.912GlnSer: 1.912 ± 0.06	1.919GlnThr: 1.919 ± 0.046	2.092GlnVal: 2.092 ± 0.048	0.391GlnTrp: 0.391 ± 0.021	1.528GlnTyr: 1.528 ± 0.039	0.0GlnXaa: 0.0 ± 0.0
Arg	2.788ArgAla: 2.788 ± 0.064	0.629ArgCys: 0.629 ± 0.028	2.333ArgAsp: 2.333 ± 0.056	3.636ArgGlu: 3.636 ± 0.067	1.75ArgPhe: 1.75 ± 0.044	2.347ArgGly: 2.347 ± 0.05	0.958ArgHis: 0.958 ± 0.035	3.478ArgIle: 3.478 ± 0.054	3.5ArgLys: 3.5 ± 0.067	3.984ArgLeu: 3.984 ± 0.069	1.737ArgMet: 1.737 ± 0.042	2.041ArgAsn: 2.041 ± 0.052	1.375ArgPro: 1.375 ± 0.031	1.972ArgGln: 1.972 ± 0.049	2.338ArgArg: 2.338 ± 0.059	2.178ArgSer: 2.178 ± 0.054	2.221ArgThr: 2.221 ± 0.045	2.77ArgVal: 2.77 ± 0.06	0.406ArgTrp: 0.406 ± 0.02	1.975ArgTyr: 1.975 ± 0.043	0.001ArgXaa: 0.001 ± 0.001
Ser	4.411SerAla: 4.411 ± 0.083	0.814SerCys: 0.814 ± 0.028	3.725SerAsp: 3.725 ± 0.066	4.235SerGlu: 4.235 ± 0.084	2.513SerPhe: 2.513 ± 0.059	4.895SerGly: 4.895 ± 0.076	1.098SerHis: 1.098 ± 0.032	3.83SerIle: 3.83 ± 0.064	3.209SerLys: 3.209 ± 0.067	4.924SerLeu: 4.924 ± 0.072	1.795SerMet: 1.795 ± 0.047	2.253SerAsn: 2.253 ± 0.049	1.658SerPro: 1.658 ± 0.04	1.964SerGln: 1.964 ± 0.047	2.694SerArg: 2.694 ± 0.063	3.401SerSer: 3.401 ± 0.079	2.74SerThr: 2.74 ± 0.055	4.291SerVal: 4.291 ± 0.064	0.55SerTrp: 0.55 ± 0.028	2.337SerTyr: 2.337 ± 0.048	0.0SerXaa: 0.0 ± 0.0
Thr	4.88ThrAla: 4.88 ± 0.083	0.674ThrCys: 0.674 ± 0.028	3.464ThrAsp: 3.464 ± 0.059	4.143ThrGlu: 4.143 ± 0.082	2.094ThrPhe: 2.094 ± 0.049	4.664ThrGly: 4.664 ± 0.08	0.928ThrHis: 0.928 ± 0.031	3.903ThrIle: 3.903 ± 0.076	2.871ThrLys: 2.871 ± 0.054	4.76ThrLeu: 4.76 ± 0.076	1.475ThrMet: 1.475 ± 0.038	2.001ThrAsn: 2.001 ± 0.046	2.075ThrPro: 2.075 ± 0.042	1.453ThrGln: 1.453 ± 0.039	1.887ThrArg: 1.887 ± 0.043	2.991ThrSer: 2.991 ± 0.061	2.947ThrThr: 2.947 ± 0.068	4.483ThrVal: 4.483 ± 0.08	0.516ThrTrp: 0.516 ± 0.027	2.05ThrTyr: 2.05 ± 0.05	0.0ThrXaa: 0.0 ± 0.0
Val	4.936ValAla: 4.936 ± 0.079	1.311ValCys: 1.311 ± 0.037	4.051ValAsp: 4.051 ± 0.07	4.202ValGlu: 4.202 ± 0.075	2.919ValPhe: 2.919 ± 0.061	4.231ValGly: 4.231 ± 0.081	1.241ValHis: 1.241 ± 0.037	5.372ValIle: 5.372 ± 0.081	4.236ValLys: 4.236 ± 0.076	6.755ValLeu: 6.755 ± 0.087	2.212ValMet: 2.212 ± 0.044	2.864ValAsn: 2.864 ± 0.055	2.574ValPro: 2.574 ± 0.051	2.104ValGln: 2.104 ± 0.047	3.082ValArg: 3.082 ± 0.061	4.6ValSer: 4.6 ± 0.071	4.188ValThr: 4.188 ± 0.061	4.885ValVal: 4.885 ± 0.092	0.582ValTrp: 0.582 ± 0.028	2.728ValTyr: 2.728 ± 0.055	0.0ValXaa: 0.0 ± 0.0
Trp	0.529TrpAla: 0.529 ± 0.025	0.145TrpCys: 0.145 ± 0.013	0.462TrpAsp: 0.462 ± 0.02	0.634TrpGlu: 0.634 ± 0.031	0.386TrpPhe: 0.386 ± 0.019	0.585TrpGly: 0.585 ± 0.028	0.24TrpHis: 0.24 ± 0.017	0.637TrpIle: 0.637 ± 0.024	0.665TrpLys: 0.665 ± 0.033	0.946TrpLeu: 0.946 ± 0.033	0.318TrpMet: 0.318 ± 0.017	0.446TrpAsn: 0.446 ± 0.023	0.255TrpPro: 0.255 ± 0.015	0.458TrpGln: 0.458 ± 0.024	0.376TrpArg: 0.376 ± 0.019	0.446TrpSer: 0.446 ± 0.021	0.432TrpThr: 0.432 ± 0.018	0.462TrpVal: 0.462 ± 0.022	0.101TrpTrp: 0.101 ± 0.011	0.408TrpTyr: 0.408 ± 0.025	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.942TyrAla: 2.942 ± 0.064	0.613TyrCys: 0.613 ± 0.024	2.744TyrAsp: 2.744 ± 0.06	2.875TyrGlu: 2.875 ± 0.055	1.746TyrPhe: 1.746 ± 0.052	2.963TyrGly: 2.963 ± 0.061	0.938TyrHis: 0.938 ± 0.032	2.845TyrIle: 2.845 ± 0.054	2.184TyrLys: 2.184 ± 0.046	3.607TyrLeu: 3.607 ± 0.065	1.204TyrMet: 1.204 ± 0.033	1.726TyrAsn: 1.726 ± 0.041	1.436TyrPro: 1.436 ± 0.036	1.53TyrGln: 1.53 ± 0.045	2.036TyrArg: 2.036 ± 0.046	2.257TyrSer: 2.257 ± 0.045	2.395TyrThr: 2.395 ± 0.056	2.625TyrVal: 2.625 ± 0.056	0.356TyrTrp: 0.356 ± 0.022	1.929TyrTyr: 1.929 ± 0.054	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.001XaaLys: 0.001 ± 0.001	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.002XaaXaa: 0.002 ± 0.002

Statistics based on 3079 proteins (982488 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---