Amino acid dipepetide frequency for Avian metaavulavirus 7

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.148AlaAla: 6.148 ± 1.645
0.878AlaCys: 0.878 ± 0.485
3.953AlaAsp: 3.953 ± 0.601
2.635AlaGlu: 2.635 ± 0.754
1.537AlaPhe: 1.537 ± 0.573
3.513AlaGly: 3.513 ± 1.541
0.878AlaHis: 0.878 ± 0.408
3.513AlaIle: 3.513 ± 0.557
3.294AlaLys: 3.294 ± 1.022
9.223AlaLeu: 9.223 ± 1.594
2.415AlaMet: 2.415 ± 1.256
3.733AlaAsn: 3.733 ± 1.187
3.513AlaPro: 3.513 ± 1.103
3.074AlaGln: 3.074 ± 2.15
2.855AlaArg: 2.855 ± 1.044
7.246AlaSer: 7.246 ± 0.781
2.196AlaThr: 2.196 ± 1.206
4.392AlaVal: 4.392 ± 1.406
0.878AlaTrp: 0.878 ± 0.408
2.415AlaTyr: 2.415 ± 0.567
0.0AlaXaa: 0.0 ± 0.0
Cys
1.098CysAla: 1.098 ± 0.435
0.659CysCys: 0.659 ± 0.387
0.878CysAsp: 0.878 ± 0.36
0.878CysGlu: 0.878 ± 0.36
0.659CysPhe: 0.659 ± 0.291
0.0CysGly: 0.0 ± 0.0
0.22CysHis: 0.22 ± 0.272
0.878CysIle: 0.878 ± 0.528
1.098CysLys: 1.098 ± 0.365
2.196CysLeu: 2.196 ± 0.609
0.22CysMet: 0.22 ± 0.129
1.098CysAsn: 1.098 ± 0.325
0.878CysPro: 0.878 ± 0.291
1.976CysGln: 1.976 ± 0.712
1.318CysArg: 1.318 ± 0.578
2.635CysSer: 2.635 ± 0.951
0.659CysThr: 0.659 ± 0.339
1.318CysVal: 1.318 ± 0.624
0.0CysTrp: 0.0 ± 0.0
0.659CysTyr: 0.659 ± 0.291
0.0CysXaa: 0.0 ± 0.0
Asp
2.196AspAla: 2.196 ± 0.703
0.439AspCys: 0.439 ± 0.259
1.976AspAsp: 1.976 ± 0.532
3.733AspGlu: 3.733 ± 0.978
1.318AspPhe: 1.318 ± 0.578
1.318AspGly: 1.318 ± 0.43
0.439AspHis: 0.439 ± 0.365
4.611AspIle: 4.611 ± 0.788
2.635AspLys: 2.635 ± 0.661
6.368AspLeu: 6.368 ± 0.919
1.537AspMet: 1.537 ± 1.146
3.074AspAsn: 3.074 ± 0.837
3.294AspPro: 3.294 ± 0.95
3.513AspGln: 3.513 ± 0.56
0.659AspArg: 0.659 ± 0.325
2.855AspSer: 2.855 ± 0.717
3.513AspThr: 3.513 ± 1.295
2.635AspVal: 2.635 ± 0.842
0.22AspTrp: 0.22 ± 0.267
1.976AspTyr: 1.976 ± 0.764
0.0AspXaa: 0.0 ± 0.0
Glu
2.415GluAla: 2.415 ± 0.503
0.659GluCys: 0.659 ± 0.387
1.318GluAsp: 1.318 ± 0.481
1.537GluGlu: 1.537 ± 0.566
2.415GluPhe: 2.415 ± 0.348
2.855GluGly: 2.855 ± 0.705
0.439GluHis: 0.439 ± 0.258
2.196GluIle: 2.196 ± 0.795
3.074GluLys: 3.074 ± 0.875
6.588GluLeu: 6.588 ± 0.992
1.318GluMet: 1.318 ± 0.855
2.635GluAsn: 2.635 ± 0.721
1.537GluPro: 1.537 ± 0.546
2.415GluGln: 2.415 ± 0.774
1.098GluArg: 1.098 ± 0.533
5.49GluSer: 5.49 ± 0.882
3.074GluThr: 3.074 ± 0.859
3.513GluVal: 3.513 ± 0.748
0.439GluTrp: 0.439 ± 0.258
1.318GluTyr: 1.318 ± 0.379
0.0GluXaa: 0.0 ± 0.0
Phe
3.513PheAla: 3.513 ± 0.988
0.878PheCys: 0.878 ± 0.516
1.757PheAsp: 1.757 ± 0.816
1.537PheGlu: 1.537 ± 0.698
2.635PhePhe: 2.635 ± 0.651
0.878PheGly: 0.878 ± 0.336
0.659PheHis: 0.659 ± 0.277
2.855PheIle: 2.855 ± 0.687
3.074PheLys: 3.074 ± 1.157
3.294PheLeu: 3.294 ± 0.83
0.22PheMet: 0.22 ± 0.289
2.196PheAsn: 2.196 ± 0.635
1.537PhePro: 1.537 ± 0.7
0.878PheGln: 0.878 ± 0.339
1.098PheArg: 1.098 ± 0.289
2.635PheSer: 2.635 ± 0.39
1.976PheThr: 1.976 ± 0.47
1.757PheVal: 1.757 ± 0.227
0.439PheTrp: 0.439 ± 0.258
0.22PheTyr: 0.22 ± 0.267
0.0PheXaa: 0.0 ± 0.0
Gly
2.415GlyAla: 2.415 ± 0.688
1.318GlyCys: 1.318 ± 0.733
3.733GlyAsp: 3.733 ± 1.58
3.074GlyGlu: 3.074 ± 0.983
2.635GlyPhe: 2.635 ± 0.81
3.074GlyGly: 3.074 ± 0.653
0.439GlyHis: 0.439 ± 0.258
5.27GlyIle: 5.27 ± 0.803
3.733GlyLys: 3.733 ± 1.639
5.929GlyLeu: 5.929 ± 0.535
0.878GlyMet: 0.878 ± 0.309
1.976GlyAsn: 1.976 ± 0.406
1.318GlyPro: 1.318 ± 0.343
1.098GlyGln: 1.098 ± 0.365
3.074GlyArg: 3.074 ± 1.133
5.49GlySer: 5.49 ± 1.386
3.074GlyThr: 3.074 ± 0.871
4.392GlyVal: 4.392 ± 1.706
0.22GlyTrp: 0.22 ± 0.129
1.098GlyTyr: 1.098 ± 0.466
0.0GlyXaa: 0.0 ± 0.0
His
0.878HisAla: 0.878 ± 0.343
0.0HisCys: 0.0 ± 0.0
1.318HisAsp: 1.318 ± 0.56
0.22HisGlu: 0.22 ± 0.129
0.439HisPhe: 0.439 ± 0.278
0.439HisGly: 0.439 ± 0.258
0.22HisHis: 0.22 ± 0.129
0.22HisIle: 0.22 ± 0.129
0.22HisLys: 0.22 ± 0.317
1.537HisLeu: 1.537 ± 0.694
0.0HisMet: 0.0 ± 0.0
1.098HisAsn: 1.098 ± 0.449
1.318HisPro: 1.318 ± 0.575
0.878HisGln: 0.878 ± 0.408
0.22HisArg: 0.22 ± 0.129
1.098HisSer: 1.098 ± 0.307
1.318HisThr: 1.318 ± 0.423
1.318HisVal: 1.318 ± 0.649
0.439HisTrp: 0.439 ± 0.24
0.439HisTyr: 0.439 ± 0.242
0.0HisXaa: 0.0 ± 0.0
Ile
6.148IleAla: 6.148 ± 1.336
0.439IleCys: 0.439 ± 0.258
2.855IleAsp: 2.855 ± 0.572
3.733IleGlu: 3.733 ± 0.532
2.855IlePhe: 2.855 ± 0.795
5.709IleGly: 5.709 ± 0.596
2.635IleHis: 2.635 ± 0.732
7.466IleIle: 7.466 ± 1.818
3.733IleLys: 3.733 ± 0.949
7.905IleLeu: 7.905 ± 1.368
1.318IleMet: 1.318 ± 0.4
4.392IleAsn: 4.392 ± 1.554
5.051IlePro: 5.051 ± 1.245
6.368IleGln: 6.368 ± 1.576
3.953IleArg: 3.953 ± 0.811
8.783IleSer: 8.783 ± 1.923
5.27IleThr: 5.27 ± 1.237
2.855IleVal: 2.855 ± 0.946
0.659IleTrp: 0.659 ± 0.278
3.074IleTyr: 3.074 ± 0.923
0.0IleXaa: 0.0 ± 0.0
Lys
3.733LysAla: 3.733 ± 0.865
0.878LysCys: 0.878 ± 0.358
0.878LysAsp: 0.878 ± 0.343
2.196LysGlu: 2.196 ± 0.786
2.196LysPhe: 2.196 ± 0.583
2.855LysGly: 2.855 ± 0.791
1.318LysHis: 1.318 ± 0.578
4.831LysIle: 4.831 ± 1.064
3.074LysLys: 3.074 ± 1.58
4.392LysLeu: 4.392 ± 0.661
1.976LysMet: 1.976 ± 0.75
3.074LysAsn: 3.074 ± 0.884
1.757LysPro: 1.757 ± 1.207
1.537LysGln: 1.537 ± 0.832
1.757LysArg: 1.757 ± 0.685
5.49LysSer: 5.49 ± 1.13
1.318LysThr: 1.318 ± 0.592
4.831LysVal: 4.831 ± 1.209
0.439LysTrp: 0.439 ± 0.258
1.537LysTyr: 1.537 ± 0.573
0.0LysXaa: 0.0 ± 0.0
Leu
7.686LeuAla: 7.686 ± 1.484
3.294LeuCys: 3.294 ± 0.807
5.709LeuAsp: 5.709 ± 1.603
6.148LeuGlu: 6.148 ± 1.574
3.074LeuPhe: 3.074 ± 1.14
6.588LeuGly: 6.588 ± 0.863
1.537LeuHis: 1.537 ± 0.742
9.881LeuIle: 9.881 ± 1.709
4.611LeuLys: 4.611 ± 1.327
12.297LeuLeu: 12.297 ± 1.806
2.196LeuMet: 2.196 ± 0.42
7.246LeuAsn: 7.246 ± 1.338
2.415LeuPro: 2.415 ± 0.963
6.368LeuGln: 6.368 ± 1.127
4.611LeuArg: 4.611 ± 1.495
9.223LeuSer: 9.223 ± 1.689
7.686LeuThr: 7.686 ± 0.684
5.709LeuVal: 5.709 ± 1.019
2.196LeuTrp: 2.196 ± 0.679
5.49LeuTyr: 5.49 ± 0.787
0.0LeuXaa: 0.0 ± 0.0
Met
1.757MetAla: 1.757 ± 0.604
0.22MetCys: 0.22 ± 0.129
1.318MetAsp: 1.318 ± 0.649
1.537MetGlu: 1.537 ± 0.387
1.318MetPhe: 1.318 ± 0.623
1.757MetGly: 1.757 ± 1.124
0.0MetHis: 0.0 ± 0.0
1.537MetIle: 1.537 ± 0.44
0.22MetLys: 0.22 ± 0.129
2.196MetLeu: 2.196 ± 0.739
1.098MetMet: 1.098 ± 0.533
0.659MetAsn: 0.659 ± 0.313
1.318MetPro: 1.318 ± 0.551
0.659MetGln: 0.659 ± 0.555
1.976MetArg: 1.976 ± 0.555
2.415MetSer: 2.415 ± 0.757
1.537MetThr: 1.537 ± 0.791
0.659MetVal: 0.659 ± 0.356
0.22MetTrp: 0.22 ± 0.129
0.22MetTyr: 0.22 ± 0.129
0.0MetXaa: 0.0 ± 0.0
Asn
2.855AsnAla: 2.855 ± 0.978
0.439AsnCys: 0.439 ± 0.363
3.074AsnAsp: 3.074 ± 0.58
1.537AsnGlu: 1.537 ± 0.763
1.757AsnPhe: 1.757 ± 0.575
2.415AsnGly: 2.415 ± 0.877
0.22AsnHis: 0.22 ± 0.317
4.831AsnIle: 4.831 ± 0.639
2.196AsnLys: 2.196 ± 0.397
7.246AsnLeu: 7.246 ± 1.132
1.098AsnMet: 1.098 ± 0.426
0.878AsnAsn: 0.878 ± 0.566
4.172AsnPro: 4.172 ± 0.663
5.051AsnGln: 5.051 ± 1.882
1.537AsnArg: 1.537 ± 0.785
3.953AsnSer: 3.953 ± 0.683
3.294AsnThr: 3.294 ± 1.319
1.757AsnVal: 1.757 ± 0.653
0.439AsnTrp: 0.439 ± 0.258
1.757AsnTyr: 1.757 ± 0.484
0.0AsnXaa: 0.0 ± 0.0
Pro
3.733ProAla: 3.733 ± 1.128
0.22ProCys: 0.22 ± 0.129
2.415ProAsp: 2.415 ± 0.862
2.855ProGlu: 2.855 ± 0.742
0.878ProPhe: 0.878 ± 0.613
2.855ProGly: 2.855 ± 0.963
0.878ProHis: 0.878 ± 0.366
4.172ProIle: 4.172 ± 0.837
1.757ProLys: 1.757 ± 0.671
4.611ProLeu: 4.611 ± 0.714
0.0ProMet: 0.0 ± 0.0
1.537ProAsn: 1.537 ± 0.747
1.976ProPro: 1.976 ± 0.398
2.415ProGln: 2.415 ± 1.404
2.196ProArg: 2.196 ± 0.419
1.976ProSer: 1.976 ± 1.294
3.953ProThr: 3.953 ± 1.27
4.392ProVal: 4.392 ± 1.42
0.22ProTrp: 0.22 ± 0.129
1.757ProTyr: 1.757 ± 0.607
0.0ProXaa: 0.0 ± 0.0
Gln
4.172GlnAla: 4.172 ± 1.26
0.659GlnCys: 0.659 ± 0.36
2.855GlnAsp: 2.855 ± 0.853
2.635GlnGlu: 2.635 ± 0.598
1.757GlnPhe: 1.757 ± 0.853
3.953GlnGly: 3.953 ± 0.525
0.659GlnHis: 0.659 ± 0.574
3.513GlnIle: 3.513 ± 0.855
2.635GlnLys: 2.635 ± 0.704
4.831GlnLeu: 4.831 ± 0.788
1.098GlnMet: 1.098 ± 0.536
3.294GlnAsn: 3.294 ± 1.611
1.976GlnPro: 1.976 ± 0.844
5.49GlnGln: 5.49 ± 1.861
2.415GlnArg: 2.415 ± 1.005
4.392GlnSer: 4.392 ± 1.126
2.855GlnThr: 2.855 ± 0.5
3.294GlnVal: 3.294 ± 1.225
0.22GlnTrp: 0.22 ± 0.129
0.878GlnTyr: 0.878 ± 0.55
0.0GlnXaa: 0.0 ± 0.0
Arg
2.635ArgAla: 2.635 ± 0.973
0.878ArgCys: 0.878 ± 0.267
1.537ArgAsp: 1.537 ± 0.569
1.976ArgGlu: 1.976 ± 1.16
0.878ArgPhe: 0.878 ± 0.566
1.757ArgGly: 1.757 ± 0.628
0.439ArgHis: 0.439 ± 0.573
3.733ArgIle: 3.733 ± 0.731
1.976ArgLys: 1.976 ± 0.529
6.807ArgLeu: 6.807 ± 1.3
0.22ArgMet: 0.22 ± 0.267
2.196ArgAsn: 2.196 ± 0.598
1.318ArgPro: 1.318 ± 0.506
2.635ArgGln: 2.635 ± 0.855
1.976ArgArg: 1.976 ± 0.974
4.392ArgSer: 4.392 ± 0.493
2.415ArgThr: 2.415 ± 0.398
3.074ArgVal: 3.074 ± 0.798
0.22ArgTrp: 0.22 ± 0.286
0.878ArgTyr: 0.878 ± 0.332
0.0ArgXaa: 0.0 ± 0.0
Ser
4.392SerAla: 4.392 ± 1.826
3.513SerCys: 3.513 ± 0.651
3.953SerAsp: 3.953 ± 0.347
3.953SerGlu: 3.953 ± 0.748
3.074SerPhe: 3.074 ± 0.448
4.611SerGly: 4.611 ± 1.461
0.659SerHis: 0.659 ± 0.278
10.76SerIle: 10.76 ± 2.954
4.611SerLys: 4.611 ± 0.928
10.979SerLeu: 10.979 ± 1.027
2.855SerMet: 2.855 ± 0.54
2.855SerAsn: 2.855 ± 0.529
4.392SerPro: 4.392 ± 0.986
3.074SerGln: 3.074 ± 0.995
2.855SerArg: 2.855 ± 1.097
9.003SerSer: 9.003 ± 2.108
5.051SerThr: 5.051 ± 1.122
4.831SerVal: 4.831 ± 0.596
1.318SerTrp: 1.318 ± 0.437
2.855SerTyr: 2.855 ± 0.484
0.0SerXaa: 0.0 ± 0.0
Thr
4.611ThrAla: 4.611 ± 1.166
1.318ThrCys: 1.318 ± 0.578
3.294ThrAsp: 3.294 ± 0.619
2.855ThrGlu: 2.855 ± 0.506
1.976ThrPhe: 1.976 ± 0.718
3.513ThrGly: 3.513 ± 0.58
0.878ThrHis: 0.878 ± 0.336
5.709ThrIle: 5.709 ± 1.285
3.513ThrLys: 3.513 ± 1.064
5.709ThrLeu: 5.709 ± 1.115
1.976ThrMet: 1.976 ± 0.514
2.635ThrAsn: 2.635 ± 0.56
3.953ThrPro: 3.953 ± 1.029
2.196ThrGln: 2.196 ± 0.71
2.855ThrArg: 2.855 ± 0.581
3.733ThrSer: 3.733 ± 1.487
5.49ThrThr: 5.49 ± 1.2
3.513ThrVal: 3.513 ± 0.986
0.878ThrTrp: 0.878 ± 0.36
1.537ThrTyr: 1.537 ± 0.33
0.0ThrXaa: 0.0 ± 0.0
Val
4.831ValAla: 4.831 ± 0.568
1.098ValCys: 1.098 ± 0.754
2.635ValAsp: 2.635 ± 1.115
2.415ValGlu: 2.415 ± 0.865
1.098ValPhe: 1.098 ± 0.348
3.733ValGly: 3.733 ± 0.871
0.659ValHis: 0.659 ± 0.387
6.148ValIle: 6.148 ± 1.274
3.294ValLys: 3.294 ± 0.821
6.807ValLeu: 6.807 ± 0.703
1.098ValMet: 1.098 ± 0.365
3.294ValAsn: 3.294 ± 1.28
1.976ValPro: 1.976 ± 0.586
2.196ValGln: 2.196 ± 0.607
3.074ValArg: 3.074 ± 0.961
4.392ValSer: 4.392 ± 1.552
4.392ValThr: 4.392 ± 1.018
2.635ValVal: 2.635 ± 0.978
1.098ValTrp: 1.098 ± 0.461
1.976ValTyr: 1.976 ± 0.689
0.0ValXaa: 0.0 ± 0.0
Trp
1.318TrpAla: 1.318 ± 0.578
0.439TrpCys: 0.439 ± 0.24
0.439TrpAsp: 0.439 ± 0.27
0.22TrpGlu: 0.22 ± 0.317
0.878TrpPhe: 0.878 ± 0.358
0.439TrpGly: 0.439 ± 0.242
0.0TrpHis: 0.0 ± 0.0
0.439TrpIle: 0.439 ± 0.278
0.439TrpLys: 0.439 ± 0.258
1.537TrpLeu: 1.537 ± 0.647
0.22TrpMet: 0.22 ± 0.129
0.0TrpAsn: 0.0 ± 0.0
0.439TrpPro: 0.439 ± 0.24
0.22TrpGln: 0.22 ± 0.129
0.878TrpArg: 0.878 ± 0.48
0.878TrpSer: 0.878 ± 0.358
0.659TrpThr: 0.659 ± 0.387
0.659TrpVal: 0.659 ± 0.573
0.0TrpTrp: 0.0 ± 0.0
0.659TrpTyr: 0.659 ± 0.278
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.757TyrAla: 1.757 ± 0.812
1.098TyrCys: 1.098 ± 0.301
2.415TyrAsp: 2.415 ± 1.005
0.659TyrGlu: 0.659 ± 0.387
0.659TyrPhe: 0.659 ± 0.291
1.976TyrGly: 1.976 ± 0.492
0.439TyrHis: 0.439 ± 0.258
2.635TyrIle: 2.635 ± 0.641
0.878TyrLys: 0.878 ± 0.267
3.733TyrLeu: 3.733 ± 1.505
0.659TyrMet: 0.659 ± 0.315
2.635TyrAsn: 2.635 ± 0.758
0.659TyrPro: 0.659 ± 0.573
1.537TyrGln: 1.537 ± 0.805
1.537TyrArg: 1.537 ± 0.428
3.513TyrSer: 3.513 ± 0.647
2.415TyrThr: 2.415 ± 0.597
1.318TyrVal: 1.318 ± 0.552
0.22TyrTrp: 0.22 ± 0.267
1.098TyrTyr: 1.098 ± 0.479
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (4555 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski