Amino acid dipepetide frequency for Shahe yuevirus-like virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.441AlaAla: 7.441 ± 9.913
1.654AlaCys: 1.654 ± 0.713
2.894AlaAsp: 2.894 ± 1.62
3.721AlaGlu: 3.721 ± 2.721
4.547AlaPhe: 4.547 ± 0.648
3.307AlaGly: 3.307 ± 1.425
2.48AlaHis: 2.48 ± 1.814
5.788AlaIle: 5.788 ± 4.73
4.134AlaLys: 4.134 ± 1.943
7.854AlaLeu: 7.854 ± 0.778
2.067AlaMet: 2.067 ± 0.518
4.134AlaAsn: 4.134 ± 1.943
2.48AlaPro: 2.48 ± 3.304
0.827AlaGln: 0.827 ± 0.389
4.134AlaArg: 4.134 ± 1.037
7.028AlaSer: 7.028 ± 1.166
2.894AlaThr: 2.894 ± 1.36
6.201AlaVal: 6.201 ± 6.025
0.827AlaTrp: 0.827 ± 2.592
1.654AlaTyr: 1.654 ± 0.713
0.0AlaXaa: 0.0 ± 0.0
Cys
0.827CysAla: 0.827 ± 2.592
0.413CysCys: 0.413 ± 0.194
0.0CysAsp: 0.0 ± 0.0
0.413CysGlu: 0.413 ± 0.194
0.827CysPhe: 0.827 ± 1.101
0.827CysGly: 0.827 ± 0.389
0.0CysHis: 0.0 ± 0.0
0.827CysIle: 0.827 ± 2.592
0.0CysLys: 0.0 ± 0.0
0.413CysLeu: 0.413 ± 0.194
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.413CysPro: 0.413 ± 0.194
0.0CysGln: 0.0 ± 0.0
0.413CysArg: 0.413 ± 0.194
0.827CysSer: 0.827 ± 0.389
0.413CysThr: 0.413 ± 0.194
0.413CysVal: 0.413 ± 0.194
0.0CysTrp: 0.0 ± 0.0
0.827CysTyr: 0.827 ± 0.389
0.0CysXaa: 0.0 ± 0.0
Asp
5.788AspAla: 5.788 ± 1.749
0.0AspCys: 0.0 ± 0.0
2.894AspAsp: 2.894 ± 1.36
3.721AspGlu: 3.721 ± 1.749
1.654AspPhe: 1.654 ± 0.713
0.827AspGly: 0.827 ± 0.389
0.827AspHis: 0.827 ± 1.101
8.268AspIle: 8.268 ± 2.397
3.307AspLys: 3.307 ± 0.065
4.547AspLeu: 4.547 ± 0.648
2.48AspMet: 2.48 ± 1.166
0.827AspAsn: 0.827 ± 0.389
0.827AspPro: 0.827 ± 0.389
0.827AspGln: 0.827 ± 0.389
2.067AspArg: 2.067 ± 0.972
2.067AspSer: 2.067 ± 0.972
4.547AspThr: 4.547 ± 3.823
3.721AspVal: 3.721 ± 0.259
0.413AspTrp: 0.413 ± 1.296
1.654AspTyr: 1.654 ± 0.777
0.0AspXaa: 0.0 ± 0.0
Glu
6.614GluAla: 6.614 ± 0.129
0.0GluCys: 0.0 ± 0.0
2.067GluAsp: 2.067 ± 0.972
4.134GluGlu: 4.134 ± 0.453
3.721GluPhe: 3.721 ± 1.749
5.374GluGly: 5.374 ± 0.454
0.413GluHis: 0.413 ± 0.194
4.961GluIle: 4.961 ± 0.842
4.961GluLys: 4.961 ± 0.842
7.441GluLeu: 7.441 ± 0.518
2.067GluMet: 2.067 ± 0.647
2.48GluAsn: 2.48 ± 1.166
2.894GluPro: 2.894 ± 0.13
1.24GluGln: 1.24 ± 0.907
2.067GluArg: 2.067 ± 0.972
3.721GluSer: 3.721 ± 1.749
3.721GluThr: 3.721 ± 1.749
4.961GluVal: 4.961 ± 2.332
0.827GluTrp: 0.827 ± 0.389
3.721GluTyr: 3.721 ± 1.749
0.0GluXaa: 0.0 ± 0.0
Phe
0.413PheAla: 0.413 ± 0.194
0.413PheCys: 0.413 ± 0.194
2.48PheAsp: 2.48 ± 1.166
3.721PheGlu: 3.721 ± 1.749
1.24PhePhe: 1.24 ± 0.583
2.48PheGly: 2.48 ± 0.324
1.24PheHis: 1.24 ± 0.583
2.067PheIle: 2.067 ± 0.972
2.067PheLys: 2.067 ± 0.972
2.067PheLeu: 2.067 ± 0.972
0.413PheMet: 0.413 ± 0.194
1.654PheAsn: 1.654 ± 0.713
2.48PhePro: 2.48 ± 0.324
0.0PheGln: 0.0 ± 0.0
2.48PheArg: 2.48 ± 0.324
6.201PheSer: 6.201 ± 3.045
0.413PheThr: 0.413 ± 0.194
2.067PheVal: 2.067 ± 0.972
0.0PheTrp: 0.0 ± 0.0
4.547PheTyr: 4.547 ± 0.648
0.0PheXaa: 0.0 ± 0.0
Gly
2.48GlyAla: 2.48 ± 1.814
0.413GlyCys: 0.413 ± 1.296
2.894GlyAsp: 2.894 ± 1.36
4.134GlyGlu: 4.134 ± 0.453
2.48GlyPhe: 2.48 ± 0.324
4.547GlyGly: 4.547 ± 5.313
0.0GlyHis: 0.0 ± 0.0
4.961GlyIle: 4.961 ± 0.842
5.374GlyLys: 5.374 ± 2.527
4.134GlyLeu: 4.134 ± 0.453
2.067GlyMet: 2.067 ± 3.499
4.961GlyAsn: 4.961 ± 2.138
1.24GlyPro: 1.24 ± 0.583
0.413GlyGln: 0.413 ± 0.194
2.067GlyArg: 2.067 ± 0.972
2.067GlySer: 2.067 ± 0.518
1.24GlyThr: 1.24 ± 0.583
3.307GlyVal: 3.307 ± 0.065
0.827GlyTrp: 0.827 ± 2.592
1.654GlyTyr: 1.654 ± 0.713
0.0GlyXaa: 0.0 ± 0.0
His
1.24HisAla: 1.24 ± 0.583
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.827HisGlu: 0.827 ± 0.389
0.413HisPhe: 0.413 ± 0.194
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
1.24HisIle: 1.24 ± 0.907
1.24HisLys: 1.24 ± 0.583
2.894HisLeu: 2.894 ± 1.36
0.413HisMet: 0.413 ± 1.296
1.654HisAsn: 1.654 ± 0.713
2.067HisPro: 2.067 ± 0.518
0.0HisGln: 0.0 ± 0.0
1.24HisArg: 1.24 ± 0.583
0.827HisSer: 0.827 ± 1.101
0.413HisThr: 0.413 ± 0.194
1.24HisVal: 1.24 ± 0.907
0.0HisTrp: 0.0 ± 0.0
0.413HisTyr: 0.413 ± 0.194
0.0HisXaa: 0.0 ± 0.0
Ile
3.307IleAla: 3.307 ± 2.916
0.413IleCys: 0.413 ± 0.194
5.374IleAsp: 5.374 ± 0.454
4.961IleGlu: 4.961 ± 2.332
2.48IlePhe: 2.48 ± 1.166
3.721IleGly: 3.721 ± 0.259
2.894IleHis: 2.894 ± 1.36
4.134IleIle: 4.134 ± 1.037
4.134IleLys: 4.134 ± 2.527
6.614IleLeu: 6.614 ± 1.619
3.721IleMet: 3.721 ± 1.749
4.547IleAsn: 4.547 ± 0.648
4.134IlePro: 4.134 ± 1.037
1.654IleGln: 1.654 ± 0.777
4.134IleArg: 4.134 ± 0.453
6.614IleSer: 6.614 ± 1.619
6.201IleThr: 6.201 ± 0.065
5.788IleVal: 5.788 ± 1.749
0.0IleTrp: 0.0 ± 0.0
2.894IleTyr: 2.894 ± 1.36
0.0IleXaa: 0.0 ± 0.0
Lys
5.374LysAla: 5.374 ± 1.036
0.0LysCys: 0.0 ± 0.0
3.307LysAsp: 3.307 ± 0.065
6.614LysGlu: 6.614 ± 1.619
2.894LysPhe: 2.894 ± 1.36
3.307LysGly: 3.307 ± 1.425
0.827LysHis: 0.827 ± 0.389
4.547LysIle: 4.547 ± 2.138
3.721LysLys: 3.721 ± 1.749
6.201LysLeu: 6.201 ± 1.425
0.413LysMet: 0.413 ± 0.194
1.654LysAsn: 1.654 ± 0.713
2.067LysPro: 2.067 ± 0.518
0.413LysGln: 0.413 ± 0.194
3.307LysArg: 3.307 ± 1.555
4.547LysSer: 4.547 ± 2.138
5.374LysThr: 5.374 ± 1.036
3.721LysVal: 3.721 ± 0.259
0.827LysTrp: 0.827 ± 0.389
1.24LysTyr: 1.24 ± 0.583
0.0LysXaa: 0.0 ± 0.0
Leu
9.508LeuAla: 9.508 ± 2.98
1.24LeuCys: 1.24 ± 2.397
5.788LeuAsp: 5.788 ± 0.259
7.028LeuGlu: 7.028 ± 3.304
2.894LeuPhe: 2.894 ± 1.36
4.961LeuGly: 4.961 ± 0.842
1.24LeuHis: 1.24 ± 0.583
7.441LeuIle: 7.441 ± 0.518
4.961LeuLys: 4.961 ± 0.648
8.268LeuLeu: 8.268 ± 2.397
5.374LeuMet: 5.374 ± 1.036
4.134LeuAsn: 4.134 ± 1.943
4.134LeuPro: 4.134 ± 1.037
2.067LeuGln: 2.067 ± 0.518
5.788LeuArg: 5.788 ± 1.231
8.268LeuSer: 8.268 ± 0.907
7.028LeuThr: 7.028 ± 1.814
8.268LeuVal: 8.268 ± 2.073
0.413LeuTrp: 0.413 ± 0.194
0.413LeuTyr: 0.413 ± 0.194
0.0LeuXaa: 0.0 ± 0.0
Met
2.894MetAla: 2.894 ± 4.6
0.0MetCys: 0.0 ± 0.0
2.48MetAsp: 2.48 ± 1.166
2.067MetGlu: 2.067 ± 0.972
1.24MetPhe: 1.24 ± 0.907
2.48MetGly: 2.48 ± 0.324
0.827MetHis: 0.827 ± 0.389
1.654MetIle: 1.654 ± 0.777
0.827MetLys: 0.827 ± 0.389
3.307MetLeu: 3.307 ± 2.916
1.654MetMet: 1.654 ± 0.777
1.24MetAsn: 1.24 ± 0.907
1.24MetPro: 1.24 ± 0.583
0.413MetGln: 0.413 ± 0.194
2.48MetArg: 2.48 ± 0.324
4.547MetSer: 4.547 ± 0.842
2.067MetThr: 2.067 ± 0.972
2.48MetVal: 2.48 ± 0.324
0.413MetTrp: 0.413 ± 0.194
1.24MetTyr: 1.24 ± 0.583
0.0MetXaa: 0.0 ± 0.0
Asn
1.654AsnAla: 1.654 ± 0.713
0.413AsnCys: 0.413 ± 0.194
2.48AsnAsp: 2.48 ± 1.814
3.307AsnGlu: 3.307 ± 1.425
1.24AsnPhe: 1.24 ± 0.583
0.827AsnGly: 0.827 ± 0.389
0.0AsnHis: 0.0 ± 0.0
3.307AsnIle: 3.307 ± 0.065
2.894AsnLys: 2.894 ± 1.36
7.441AsnLeu: 7.441 ± 3.498
2.48AsnMet: 2.48 ± 1.166
2.48AsnAsn: 2.48 ± 1.166
3.721AsnPro: 3.721 ± 1.231
0.413AsnGln: 0.413 ± 1.296
0.827AsnArg: 0.827 ± 1.101
4.134AsnSer: 4.134 ± 1.943
2.894AsnThr: 2.894 ± 0.13
2.067AsnVal: 2.067 ± 0.518
0.413AsnTrp: 0.413 ± 0.194
3.721AsnTyr: 3.721 ± 1.749
0.0AsnXaa: 0.0 ± 0.0
Pro
3.721ProAla: 3.721 ± 1.231
0.0ProCys: 0.0 ± 0.0
2.067ProAsp: 2.067 ± 2.008
3.721ProGlu: 3.721 ± 0.259
1.24ProPhe: 1.24 ± 0.583
1.654ProGly: 1.654 ± 0.777
2.48ProHis: 2.48 ± 0.324
1.654ProIle: 1.654 ± 0.777
2.48ProLys: 2.48 ± 1.166
4.134ProLeu: 4.134 ± 4.017
1.24ProMet: 1.24 ± 0.583
1.654ProAsn: 1.654 ± 0.777
2.067ProPro: 2.067 ± 0.518
0.827ProGln: 0.827 ± 1.101
3.721ProArg: 3.721 ± 0.259
2.067ProSer: 2.067 ± 0.972
2.48ProThr: 2.48 ± 4.794
4.134ProVal: 4.134 ± 0.453
0.413ProTrp: 0.413 ± 1.296
2.48ProTyr: 2.48 ± 1.166
0.0ProXaa: 0.0 ± 0.0
Gln
1.654GlnAla: 1.654 ± 2.203
0.0GlnCys: 0.0 ± 0.0
0.827GlnAsp: 0.827 ± 0.389
0.827GlnGlu: 0.827 ± 0.389
0.827GlnPhe: 0.827 ± 0.389
0.827GlnGly: 0.827 ± 1.101
0.0GlnHis: 0.0 ± 0.0
1.24GlnIle: 1.24 ± 0.583
0.827GlnLys: 0.827 ± 0.389
1.654GlnLeu: 1.654 ± 0.713
0.0GlnMet: 0.0 ± 0.65
0.413GlnAsn: 0.413 ± 0.194
1.654GlnPro: 1.654 ± 0.713
1.24GlnGln: 1.24 ± 0.583
0.413GlnArg: 0.413 ± 0.194
2.067GlnSer: 2.067 ± 0.972
0.0GlnThr: 0.0 ± 0.0
2.48GlnVal: 2.48 ± 0.324
0.0GlnTrp: 0.0 ± 0.0
0.827GlnTyr: 0.827 ± 0.389
0.0GlnXaa: 0.0 ± 0.0
Arg
6.614ArgAla: 6.614 ± 2.851
0.413ArgCys: 0.413 ± 0.194
1.24ArgAsp: 1.24 ± 0.907
2.48ArgGlu: 2.48 ± 0.324
1.654ArgPhe: 1.654 ± 0.713
3.721ArgGly: 3.721 ± 1.749
0.0ArgHis: 0.0 ± 0.0
4.961ArgIle: 4.961 ± 0.648
2.48ArgLys: 2.48 ± 1.166
6.614ArgLeu: 6.614 ± 0.129
2.067ArgMet: 2.067 ± 0.972
2.48ArgAsn: 2.48 ± 1.166
1.654ArgPro: 1.654 ± 0.713
1.24ArgGln: 1.24 ± 0.583
3.307ArgArg: 3.307 ± 0.065
7.028ArgSer: 7.028 ± 0.324
2.48ArgThr: 2.48 ± 0.324
4.961ArgVal: 4.961 ± 2.332
0.0ArgTrp: 0.0 ± 0.0
2.067ArgTyr: 2.067 ± 0.518
0.0ArgXaa: 0.0 ± 0.0
Ser
5.374SerAla: 5.374 ± 4.924
0.413SerCys: 0.413 ± 0.194
4.961SerAsp: 4.961 ± 2.332
5.788SerGlu: 5.788 ± 1.231
2.48SerPhe: 2.48 ± 0.324
4.547SerGly: 4.547 ± 2.332
0.413SerHis: 0.413 ± 0.194
3.721SerIle: 3.721 ± 1.231
6.201SerLys: 6.201 ± 0.065
9.508SerLeu: 9.508 ± 4.47
2.48SerMet: 2.48 ± 0.324
4.134SerAsn: 4.134 ± 0.453
3.721SerPro: 3.721 ± 0.259
1.24SerGln: 1.24 ± 0.583
5.374SerArg: 5.374 ± 2.527
5.374SerSer: 5.374 ± 1.036
4.547SerThr: 4.547 ± 0.842
5.788SerVal: 5.788 ± 2.721
0.413SerTrp: 0.413 ± 0.194
2.894SerTyr: 2.894 ± 0.13
0.0SerXaa: 0.0 ± 0.0
Thr
4.961ThrAla: 4.961 ± 0.648
0.413ThrCys: 0.413 ± 0.194
4.547ThrAsp: 4.547 ± 0.842
4.134ThrGlu: 4.134 ± 0.453
2.894ThrPhe: 2.894 ± 0.13
1.24ThrGly: 1.24 ± 0.583
0.827ThrHis: 0.827 ± 1.101
6.201ThrIle: 6.201 ± 2.915
2.894ThrLys: 2.894 ± 1.36
4.134ThrLeu: 4.134 ± 0.453
2.48ThrMet: 2.48 ± 3.304
3.721ThrAsn: 3.721 ± 1.231
2.48ThrPro: 2.48 ± 0.324
1.654ThrGln: 1.654 ± 0.713
4.547ThrArg: 4.547 ± 3.823
3.721ThrSer: 3.721 ± 0.259
3.721ThrThr: 3.721 ± 0.259
2.067ThrVal: 2.067 ± 0.972
0.827ThrTrp: 0.827 ± 0.389
1.654ThrTyr: 1.654 ± 0.777
0.0ThrXaa: 0.0 ± 0.0
Val
4.547ValAla: 4.547 ± 2.332
1.654ValCys: 1.654 ± 0.713
2.894ValAsp: 2.894 ± 1.36
3.721ValGlu: 3.721 ± 1.749
2.067ValPhe: 2.067 ± 0.972
4.547ValGly: 4.547 ± 2.332
0.827ValHis: 0.827 ± 0.389
5.374ValIle: 5.374 ± 1.036
4.134ValLys: 4.134 ± 1.943
6.614ValLeu: 6.614 ± 0.129
2.067ValMet: 2.067 ± 0.518
2.067ValAsn: 2.067 ± 0.972
3.721ValPro: 3.721 ± 0.259
2.067ValGln: 2.067 ± 2.008
6.201ValArg: 6.201 ± 0.065
5.788ValSer: 5.788 ± 0.259
4.961ValThr: 4.961 ± 0.648
3.721ValVal: 3.721 ± 1.231
1.24ValTrp: 1.24 ± 0.583
2.067ValTyr: 2.067 ± 0.518
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.413TrpAsp: 0.413 ± 0.194
1.24TrpGlu: 1.24 ± 0.583
0.0TrpPhe: 0.0 ± 0.0
0.413TrpGly: 0.413 ± 1.296
0.0TrpHis: 0.0 ± 0.0
0.827TrpIle: 0.827 ± 1.101
0.413TrpLys: 0.413 ± 0.194
1.24TrpLeu: 1.24 ± 0.583
0.413TrpMet: 0.413 ± 1.296
0.413TrpAsn: 0.413 ± 0.194
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.413TrpArg: 0.413 ± 1.296
1.24TrpSer: 1.24 ± 0.907
0.413TrpThr: 0.413 ± 1.296
0.413TrpVal: 0.413 ± 0.194
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.654TyrAla: 1.654 ± 0.777
0.0TyrCys: 0.0 ± 0.0
1.654TyrAsp: 1.654 ± 0.777
0.827TyrGlu: 0.827 ± 0.389
1.654TyrPhe: 1.654 ± 0.713
1.654TyrGly: 1.654 ± 0.777
0.827TyrHis: 0.827 ± 1.101
4.547TyrIle: 4.547 ± 2.138
3.307TyrLys: 3.307 ± 0.065
4.134TyrLeu: 4.134 ± 1.943
1.24TyrMet: 1.24 ± 0.583
2.067TyrAsn: 2.067 ± 0.518
1.24TyrPro: 1.24 ± 0.583
1.654TyrGln: 1.654 ± 0.777
2.48TyrArg: 2.48 ± 0.324
1.24TyrSer: 1.24 ± 0.583
3.307TyrThr: 3.307 ± 0.065
2.48TyrVal: 2.48 ± 1.166
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2420 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski