Amino acid dipepetide frequency for Fusarium longipes

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.331AlaAla: 8.331 ± 0.057	1.065AlaCys: 1.065 ± 0.013	4.184AlaAsp: 4.184 ± 0.029	5.041AlaGlu: 5.041 ± 0.049	3.068AlaPhe: 3.068 ± 0.026	5.44AlaGly: 5.44 ± 0.037	1.667AlaHis: 1.667 ± 0.019	4.441AlaIle: 4.441 ± 0.033	4.177AlaLys: 4.177 ± 0.031	7.39AlaLeu: 7.39 ± 0.044	1.998AlaMet: 1.998 ± 0.018	2.962AlaAsn: 2.962 ± 0.024	4.676AlaPro: 4.676 ± 0.045	3.315AlaGln: 3.315 ± 0.03	4.5AlaArg: 4.5 ± 0.03	6.977AlaSer: 6.977 ± 0.037	5.185AlaThr: 5.185 ± 0.031	5.19AlaVal: 5.19 ± 0.035	1.18AlaTrp: 1.18 ± 0.014	2.101AlaTyr: 2.101 ± 0.021	0.0AlaXaa: 0.0 ± 0.0
Cys	0.917CysAla: 0.917 ± 0.013	0.24CysCys: 0.24 ± 0.008	0.698CysAsp: 0.698 ± 0.014	0.613CysGlu: 0.613 ± 0.012	0.557CysPhe: 0.557 ± 0.011	0.939CysGly: 0.939 ± 0.017	0.334CysHis: 0.334 ± 0.007	0.74CysIle: 0.74 ± 0.01	0.57CysLys: 0.57 ± 0.012	1.215CysLeu: 1.215 ± 0.017	0.268CysMet: 0.268 ± 0.006	0.47CysAsn: 0.47 ± 0.009	0.652CysPro: 0.652 ± 0.012	0.471CysGln: 0.471 ± 0.01	0.712CysArg: 0.712 ± 0.011	0.898CysSer: 0.898 ± 0.015	0.704CysThr: 0.704 ± 0.013	0.819CysVal: 0.819 ± 0.016	0.219CysTrp: 0.219 ± 0.007	0.369CysTyr: 0.369 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	4.722AspAla: 4.722 ± 0.034	0.671AspCys: 0.671 ± 0.013	4.695AspAsp: 4.695 ± 0.044	4.747AspGlu: 4.747 ± 0.036	2.318AspPhe: 2.318 ± 0.019	4.103AspGly: 4.103 ± 0.032	1.274AspHis: 1.274 ± 0.017	3.345AspIle: 3.345 ± 0.031	2.821AspLys: 2.821 ± 0.026	5.142AspLeu: 5.142 ± 0.035	1.396AspMet: 1.396 ± 0.015	2.154AspAsn: 2.154 ± 0.019	3.288AspPro: 3.288 ± 0.029	2.014AspGln: 2.014 ± 0.021	3.049AspArg: 3.049 ± 0.033	4.314AspSer: 4.314 ± 0.036	3.175AspThr: 3.175 ± 0.028	3.797AspVal: 3.797 ± 0.027	0.946AspTrp: 0.946 ± 0.014	1.667AspTyr: 1.667 ± 0.016	0.001AspXaa: 0.001 ± 0.0
Glu	5.509GluAla: 5.509 ± 0.044	0.658GluCys: 0.658 ± 0.013	4.348GluAsp: 4.348 ± 0.036	5.485GluGlu: 5.485 ± 0.058	2.048GluPhe: 2.048 ± 0.021	3.667GluGly: 3.667 ± 0.025	1.422GluHis: 1.422 ± 0.019	3.109GluIle: 3.109 ± 0.028	3.849GluLys: 3.849 ± 0.033	5.16GluLeu: 5.16 ± 0.035	1.488GluMet: 1.488 ± 0.015	2.46GluAsn: 2.46 ± 0.023	3.011GluPro: 3.011 ± 0.036	2.52GluGln: 2.52 ± 0.028	3.752GluArg: 3.752 ± 0.037	4.445GluSer: 4.445 ± 0.03	3.849GluThr: 3.849 ± 0.033	3.6GluVal: 3.6 ± 0.025	0.927GluTrp: 0.927 ± 0.013	1.7GluTyr: 1.7 ± 0.018	0.0GluXaa: 0.0 ± 0.0
Phe	2.967PheAla: 2.967 ± 0.024	0.568PheCys: 0.568 ± 0.012	2.377PheAsp: 2.377 ± 0.022	2.229PheGlu: 2.229 ± 0.022	1.654PhePhe: 1.654 ± 0.02	2.878PheGly: 2.878 ± 0.031	0.898PheHis: 0.898 ± 0.013	1.911PheIle: 1.911 ± 0.02	1.66PheLys: 1.66 ± 0.017	3.383PheLeu: 3.383 ± 0.032	0.831PheMet: 0.831 ± 0.013	1.535PheAsn: 1.535 ± 0.017	1.872PhePro: 1.872 ± 0.018	1.435PheGln: 1.435 ± 0.017	1.879PheArg: 1.879 ± 0.02	2.955PheSer: 2.955 ± 0.024	2.222PheThr: 2.222 ± 0.023	2.445PheVal: 2.445 ± 0.024	0.674PheTrp: 0.674 ± 0.013	1.128PheTyr: 1.128 ± 0.014	0.0PheXaa: 0.0 ± 0.0
Gly	5.02GlyAla: 5.02 ± 0.041	0.887GlyCys: 0.887 ± 0.013	3.741GlyAsp: 3.741 ± 0.032	3.518GlyGlu: 3.518 ± 0.028	2.813GlyPhe: 2.813 ± 0.025	5.392GlyGly: 5.392 ± 0.05	1.681GlyHis: 1.681 ± 0.021	3.631GlyIle: 3.631 ± 0.032	3.455GlyLys: 3.455 ± 0.029	5.991GlyLeu: 5.991 ± 0.042	1.561GlyMet: 1.561 ± 0.017	2.691GlyAsn: 2.691 ± 0.023	3.216GlyPro: 3.216 ± 0.029	2.601GlyGln: 2.601 ± 0.021	3.916GlyArg: 3.916 ± 0.029	5.62GlySer: 5.62 ± 0.041	3.988GlyThr: 3.988 ± 0.032	4.229GlyVal: 4.229 ± 0.032	1.183GlyTrp: 1.183 ± 0.016	2.186GlyTyr: 2.186 ± 0.021	0.0GlyXaa: 0.0 ± 0.0
His	1.689HisAla: 1.689 ± 0.017	0.322HisCys: 0.322 ± 0.007	1.44HisAsp: 1.44 ± 0.017	1.383HisGlu: 1.383 ± 0.016	0.899HisPhe: 0.899 ± 0.013	1.687HisGly: 1.687 ± 0.018	0.843HisHis: 0.843 ± 0.02	1.234HisIle: 1.234 ± 0.017	0.983HisLys: 0.983 ± 0.017	2.17HisLeu: 2.17 ± 0.023	0.514HisMet: 0.514 ± 0.01	0.885HisAsn: 0.885 ± 0.013	1.508HisPro: 1.508 ± 0.017	1.02HisGln: 1.02 ± 0.014	1.459HisArg: 1.459 ± 0.018	1.745HisSer: 1.745 ± 0.019	1.188HisThr: 1.188 ± 0.015	1.429HisVal: 1.429 ± 0.015	0.349HisTrp: 0.349 ± 0.008	0.71HisTyr: 0.71 ± 0.013	0.0HisXaa: 0.0 ± 0.0
Ile	4.298IleAla: 4.298 ± 0.031	0.776IleCys: 0.776 ± 0.013	3.1IleAsp: 3.1 ± 0.025	3.121IleGlu: 3.121 ± 0.024	2.037IlePhe: 2.037 ± 0.022	3.29IleGly: 3.29 ± 0.029	1.205IleHis: 1.205 ± 0.016	2.689IleIle: 2.689 ± 0.027	2.435IleLys: 2.435 ± 0.02	4.57IleLeu: 4.57 ± 0.035	1.104IleMet: 1.104 ± 0.015	1.98IleAsn: 1.98 ± 0.021	3.068IlePro: 3.068 ± 0.026	1.959IleGln: 1.959 ± 0.019	2.783IleArg: 2.783 ± 0.024	3.939IleSer: 3.939 ± 0.027	3.003IleThr: 3.003 ± 0.025	3.383IleVal: 3.383 ± 0.028	0.807IleTrp: 0.807 ± 0.012	1.462IleTyr: 1.462 ± 0.014	0.0IleXaa: 0.0 ± 0.0
Lys	4.394LysAla: 4.394 ± 0.035	0.546LysCys: 0.546 ± 0.013	3.206LysAsp: 3.206 ± 0.026	3.553LysGlu: 3.553 ± 0.033	1.558LysPhe: 1.558 ± 0.018	3.106LysGly: 3.106 ± 0.029	1.193LysHis: 1.193 ± 0.016	2.419LysIle: 2.419 ± 0.021	3.628LysLys: 3.628 ± 0.044	4.213LysLeu: 4.213 ± 0.026	1.07LysMet: 1.07 ± 0.015	1.972LysAsn: 1.972 ± 0.019	2.955LysPro: 2.955 ± 0.027	1.963LysGln: 1.963 ± 0.021	3.352LysArg: 3.352 ± 0.03	3.702LysSer: 3.702 ± 0.033	3.175LysThr: 3.175 ± 0.027	2.981LysVal: 2.981 ± 0.026	0.743LysTrp: 0.743 ± 0.012	1.453LysTyr: 1.453 ± 0.018	0.0LysXaa: 0.0 ± 0.0
Leu	7.456LeuAla: 7.456 ± 0.045	1.18LeuCys: 1.18 ± 0.016	5.221LeuAsp: 5.221 ± 0.039	5.482LeuGlu: 5.482 ± 0.035	3.277LeuPhe: 3.277 ± 0.032	5.749LeuGly: 5.749 ± 0.039	2.072LeuHis: 2.072 ± 0.023	4.065LeuIle: 4.065 ± 0.03	4.322LeuLys: 4.322 ± 0.03	7.803LeuLeu: 7.803 ± 0.057	1.814LeuMet: 1.814 ± 0.017	3.209LeuAsn: 3.209 ± 0.021	5.209LeuPro: 5.209 ± 0.031	3.635LeuGln: 3.635 ± 0.031	5.318LeuArg: 5.318 ± 0.035	7.034LeuSer: 7.034 ± 0.043	4.754LeuThr: 4.754 ± 0.033	5.408LeuVal: 5.408 ± 0.036	1.218LeuTrp: 1.218 ± 0.016	2.33LeuTyr: 2.33 ± 0.021	0.0LeuXaa: 0.0 ± 0.0
Met	2.257MetAla: 2.257 ± 0.021	0.244MetCys: 0.244 ± 0.007	1.305MetAsp: 1.305 ± 0.015	1.305MetGlu: 1.305 ± 0.014	0.786MetPhe: 0.786 ± 0.012	1.502MetGly: 1.502 ± 0.017	0.475MetHis: 0.475 ± 0.009	1.067MetIle: 1.067 ± 0.014	1.071MetLys: 1.071 ± 0.016	1.811MetLeu: 1.811 ± 0.018	0.63MetMet: 0.63 ± 0.01	0.859MetAsn: 0.859 ± 0.013	1.314MetPro: 1.314 ± 0.017	0.832MetGln: 0.832 ± 0.013	1.238MetArg: 1.238 ± 0.016	2.015MetSer: 2.015 ± 0.019	1.395MetThr: 1.395 ± 0.013	1.323MetVal: 1.323 ± 0.015	0.278MetTrp: 0.278 ± 0.007	0.539MetTyr: 0.539 ± 0.008	0.0MetXaa: 0.0 ± 0.0
Asn	3.107AsnAla: 3.107 ± 0.025	0.482AsnCys: 0.482 ± 0.01	2.233AsnAsp: 2.233 ± 0.021	2.186AsnGlu: 2.186 ± 0.024	1.436AsnPhe: 1.436 ± 0.017	3.091AsnGly: 3.091 ± 0.027	0.906AsnHis: 0.906 ± 0.014	2.157AsnIle: 2.157 ± 0.02	1.865AsnLys: 1.865 ± 0.02	3.298AsnLeu: 3.298 ± 0.025	0.941AsnMet: 0.941 ± 0.013	1.718AsnAsn: 1.718 ± 0.02	2.443AsnPro: 2.443 ± 0.021	1.438AsnGln: 1.438 ± 0.017	1.982AsnArg: 1.982 ± 0.02	2.931AsnSer: 2.931 ± 0.024	2.322AsnThr: 2.322 ± 0.021	2.39AsnVal: 2.39 ± 0.024	0.595AsnTrp: 0.595 ± 0.01	1.114AsnTyr: 1.114 ± 0.016	0.0AsnXaa: 0.0 ± 0.0
Pro	4.872ProAla: 4.872 ± 0.044	0.504ProCys: 0.504 ± 0.01	3.301ProAsp: 3.301 ± 0.027	4.001ProGlu: 4.001 ± 0.035	2.034ProPhe: 2.034 ± 0.021	3.892ProGly: 3.892 ± 0.042	1.242ProHis: 1.242 ± 0.015	2.596ProIle: 2.596 ± 0.023	2.861ProLys: 2.861 ± 0.027	4.449ProLeu: 4.449 ± 0.035	1.107ProMet: 1.107 ± 0.014	2.23ProAsn: 2.23 ± 0.02	4.667ProPro: 4.667 ± 0.065	2.491ProGln: 2.491 ± 0.03	3.219ProArg: 3.219 ± 0.032	5.677ProSer: 5.677 ± 0.047	3.904ProThr: 3.904 ± 0.039	3.654ProVal: 3.654 ± 0.032	0.755ProTrp: 0.755 ± 0.012	1.509ProTyr: 1.509 ± 0.017	0.0ProXaa: 0.0 ± 0.0
Gln	3.397GlnAla: 3.397 ± 0.028	0.433GlnCys: 0.433 ± 0.009	2.355GlnAsp: 2.355 ± 0.022	2.511GlnGlu: 2.511 ± 0.024	1.293GlnPhe: 1.293 ± 0.016	2.493GlnGly: 2.493 ± 0.023	1.063GlnHis: 1.063 ± 0.014	1.913GlnIle: 1.913 ± 0.019	2.041GlnLys: 2.041 ± 0.023	3.35GlnLeu: 3.35 ± 0.032	0.885GlnMet: 0.885 ± 0.014	1.64GlnAsn: 1.64 ± 0.021	2.58GlnPro: 2.58 ± 0.034	2.436GlnGln: 2.436 ± 0.052	2.505GlnArg: 2.505 ± 0.024	3.1GlnSer: 3.1 ± 0.029	2.337GlnThr: 2.337 ± 0.022	2.25GlnVal: 2.25 ± 0.021	0.596GlnTrp: 0.596 ± 0.01	1.167GlnTyr: 1.167 ± 0.014	0.0GlnXaa: 0.0 ± 0.0
Arg	4.265ArgAla: 4.265 ± 0.031	0.673ArgCys: 0.673 ± 0.012	3.431ArgAsp: 3.431 ± 0.034	3.633ArgGlu: 3.633 ± 0.031	2.087ArgPhe: 2.087 ± 0.019	3.531ArgGly: 3.531 ± 0.031	1.504ArgHis: 1.504 ± 0.02	2.843ArgIle: 2.843 ± 0.027	3.324ArgLys: 3.324 ± 0.027	5.143ArgLeu: 5.143 ± 0.038	1.279ArgMet: 1.279 ± 0.015	2.293ArgAsn: 2.293 ± 0.022	3.36ArgPro: 3.36 ± 0.032	2.531ArgGln: 2.531 ± 0.022	4.726ArgArg: 4.726 ± 0.053	4.534ArgSer: 4.534 ± 0.037	3.131ArgThr: 3.131 ± 0.026	3.233ArgVal: 3.233 ± 0.023	0.907ArgTrp: 0.907 ± 0.012	1.645ArgTyr: 1.645 ± 0.018	0.0ArgXaa: 0.0 ± 0.0
Ser	6.216SerAla: 6.216 ± 0.04	0.888SerCys: 0.888 ± 0.014	4.463SerAsp: 4.463 ± 0.032	4.337SerGlu: 4.337 ± 0.034	3.105SerPhe: 3.105 ± 0.024	5.42SerGly: 5.42 ± 0.035	1.931SerHis: 1.931 ± 0.019	4.166SerIle: 4.166 ± 0.028	3.983SerLys: 3.983 ± 0.033	6.952SerLeu: 6.952 ± 0.04	1.758SerMet: 1.758 ± 0.017	3.145SerAsn: 3.145 ± 0.026	5.186SerPro: 5.186 ± 0.046	3.344SerGln: 3.344 ± 0.031	4.793SerArg: 4.793 ± 0.037	8.265SerSer: 8.265 ± 0.067	5.52SerThr: 5.52 ± 0.048	4.602SerVal: 4.602 ± 0.031	1.189SerTrp: 1.189 ± 0.017	2.12SerTyr: 2.12 ± 0.021	0.0SerXaa: 0.0 ± 0.0
Thr	5.042ThrAla: 5.042 ± 0.033	0.784ThrCys: 0.784 ± 0.014	3.03ThrAsp: 3.03 ± 0.023	3.412ThrGlu: 3.412 ± 0.034	2.264ThrPhe: 2.264 ± 0.021	4.152ThrGly: 4.152 ± 0.033	1.259ThrHis: 1.259 ± 0.015	3.358ThrIle: 3.358 ± 0.035	2.92ThrLys: 2.92 ± 0.024	5.131ThrLeu: 5.131 ± 0.032	1.218ThrMet: 1.218 ± 0.015	2.269ThrAsn: 2.269 ± 0.02	4.259ThrPro: 4.259 ± 0.036	2.221ThrGln: 2.221 ± 0.027	3.105ThrArg: 3.105 ± 0.025	5.372ThrSer: 5.372 ± 0.05	4.594ThrThr: 4.594 ± 0.073	3.852ThrVal: 3.852 ± 0.039	0.924ThrTrp: 0.924 ± 0.014	1.641ThrTyr: 1.641 ± 0.017	0.0ThrXaa: 0.0 ± 0.0
Val	5.175ValAla: 5.175 ± 0.035	0.84ValCys: 0.84 ± 0.014	3.824ValAsp: 3.824 ± 0.028	3.958ValGlu: 3.958 ± 0.03	2.49ValPhe: 2.49 ± 0.026	3.903ValGly: 3.903 ± 0.036	1.359ValHis: 1.359 ± 0.016	3.101ValIle: 3.101 ± 0.029	3.111ValLys: 3.111 ± 0.029	5.43ValLeu: 5.43 ± 0.036	1.355ValMet: 1.355 ± 0.016	2.284ValAsn: 2.284 ± 0.021	3.612ValPro: 3.612 ± 0.034	2.367ValGln: 2.367 ± 0.021	3.249ValArg: 3.249 ± 0.026	4.699ValSer: 4.699 ± 0.033	3.738ValThr: 3.738 ± 0.036	4.313ValVal: 4.313 ± 0.035	0.877ValTrp: 0.877 ± 0.014	1.751ValTyr: 1.751 ± 0.017	0.0ValXaa: 0.0 ± 0.0
Trp	1.166TrpAla: 1.166 ± 0.019	0.21TrpCys: 0.21 ± 0.007	0.953TrpAsp: 0.953 ± 0.014	0.884TrpGlu: 0.884 ± 0.013	0.585TrpPhe: 0.585 ± 0.01	0.975TrpGly: 0.975 ± 0.013	0.366TrpHis: 0.366 ± 0.009	0.832TrpIle: 0.832 ± 0.014	0.868TrpLys: 0.868 ± 0.013	1.377TrpLeu: 1.377 ± 0.017	0.38TrpMet: 0.38 ± 0.01	0.672TrpAsn: 0.672 ± 0.01	0.632TrpPro: 0.632 ± 0.011	0.606TrpGln: 0.606 ± 0.011	0.912TrpArg: 0.912 ± 0.014	1.1TrpSer: 1.1 ± 0.015	0.976TrpThr: 0.976 ± 0.014	0.894TrpVal: 0.894 ± 0.013	0.293TrpTrp: 0.293 ± 0.008	0.455TrpTyr: 0.455 ± 0.01	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.088TyrAla: 2.088 ± 0.021	0.437TyrCys: 0.437 ± 0.009	1.733TyrAsp: 1.733 ± 0.019	1.607TyrGlu: 1.607 ± 0.018	1.191TyrPhe: 1.191 ± 0.014	2.112TyrGly: 2.112 ± 0.023	0.761TyrHis: 0.761 ± 0.012	1.392TyrIle: 1.392 ± 0.017	1.239TyrLys: 1.239 ± 0.018	2.58TyrLeu: 2.58 ± 0.024	0.648TyrMet: 0.648 ± 0.011	1.207TyrAsn: 1.207 ± 0.014	1.457TyrPro: 1.457 ± 0.019	1.145TyrGln: 1.145 ± 0.016	1.626TyrArg: 1.626 ± 0.018	2.06TyrSer: 2.06 ± 0.021	1.645TyrThr: 1.645 ± 0.019	1.643TyrVal: 1.643 ± 0.017	0.476TyrTrp: 0.476 ± 0.01	0.938TyrTyr: 0.938 ± 0.015	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.017XaaXaa: 0.017 ± 0.009

Statistics based on 11420 proteins (5842010 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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