Amino acid dipepetide frequency for Emergomyces pasteurianus Ep9510

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.198AlaAla: 8.198 ± 0.063	0.948AlaCys: 0.948 ± 0.015	3.914AlaAsp: 3.914 ± 0.033	4.942AlaGlu: 4.942 ± 0.043	2.851AlaPhe: 2.851 ± 0.033	5.462AlaGly: 5.462 ± 0.04	1.702AlaHis: 1.702 ± 0.022	4.125AlaIle: 4.125 ± 0.035	3.988AlaLys: 3.988 ± 0.037	7.168AlaLeu: 7.168 ± 0.041	1.702AlaMet: 1.702 ± 0.021	2.934AlaAsn: 2.934 ± 0.027	4.371AlaPro: 4.371 ± 0.043	3.069AlaGln: 3.069 ± 0.03	4.695AlaArg: 4.695 ± 0.04	6.93AlaSer: 6.93 ± 0.048	5.023AlaThr: 5.023 ± 0.037	4.895AlaVal: 4.895 ± 0.037	0.921AlaTrp: 0.921 ± 0.015	1.899AlaTyr: 1.899 ± 0.021	0.0AlaXaa: 0.0 ± 0.0
Cys	0.855CysAla: 0.855 ± 0.012	0.235CysCys: 0.235 ± 0.009	0.643CysAsp: 0.643 ± 0.014	0.629CysGlu: 0.629 ± 0.012	0.502CysPhe: 0.502 ± 0.011	0.9CysGly: 0.9 ± 0.015	0.344CysHis: 0.344 ± 0.011	0.683CysIle: 0.683 ± 0.013	0.532CysLys: 0.532 ± 0.011	1.237CysLeu: 1.237 ± 0.022	0.255CysMet: 0.255 ± 0.008	0.426CysAsn: 0.426 ± 0.01	0.668CysPro: 0.668 ± 0.014	0.452CysGln: 0.452 ± 0.01	0.762CysArg: 0.762 ± 0.014	0.947CysSer: 0.947 ± 0.018	0.647CysThr: 0.647 ± 0.013	0.74CysVal: 0.74 ± 0.014	0.187CysTrp: 0.187 ± 0.008	0.339CysTyr: 0.339 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	4.184AspAla: 4.184 ± 0.034	0.61AspCys: 0.61 ± 0.012	4.321AspAsp: 4.321 ± 0.051	4.423AspGlu: 4.423 ± 0.041	2.108AspPhe: 2.108 ± 0.022	4.038AspGly: 4.038 ± 0.031	1.231AspHis: 1.231 ± 0.021	3.415AspIle: 3.415 ± 0.033	2.396AspLys: 2.396 ± 0.026	4.879AspLeu: 4.879 ± 0.04	1.258AspMet: 1.258 ± 0.018	2.05AspAsn: 2.05 ± 0.024	3.315AspPro: 3.315 ± 0.032	1.812AspGln: 1.812 ± 0.023	3.143AspArg: 3.143 ± 0.035	4.225AspSer: 4.225 ± 0.034	2.961AspThr: 2.961 ± 0.029	3.501AspVal: 3.501 ± 0.033	0.774AspTrp: 0.774 ± 0.013	1.495AspTyr: 1.495 ± 0.02	0.0AspXaa: 0.0 ± 0.0
Glu	4.918GluAla: 4.918 ± 0.041	0.636GluCys: 0.636 ± 0.015	4.059GluAsp: 4.059 ± 0.04	5.481GluGlu: 5.481 ± 0.059	1.993GluPhe: 1.993 ± 0.022	3.782GluGly: 3.782 ± 0.031	1.421GluHis: 1.421 ± 0.019	3.265GluIle: 3.265 ± 0.028	3.901GluLys: 3.901 ± 0.038	5.297GluLeu: 5.297 ± 0.05	1.483GluMet: 1.483 ± 0.021	2.688GluAsn: 2.688 ± 0.025	2.805GluPro: 2.805 ± 0.035	2.501GluGln: 2.501 ± 0.026	4.109GluArg: 4.109 ± 0.04	4.418GluSer: 4.418 ± 0.034	3.41GluThr: 3.41 ± 0.033	3.361GluVal: 3.361 ± 0.032	0.846GluTrp: 0.846 ± 0.014	1.714GluTyr: 1.714 ± 0.022	0.0GluXaa: 0.0 ± 0.0
Phe	2.784PheAla: 2.784 ± 0.026	0.547PheCys: 0.547 ± 0.012	2.21PheAsp: 2.21 ± 0.023	2.167PheGlu: 2.167 ± 0.026	1.496PhePhe: 1.496 ± 0.023	2.683PheGly: 2.683 ± 0.031	0.936PheHis: 0.936 ± 0.016	1.813PheIle: 1.813 ± 0.022	1.561PheLys: 1.561 ± 0.021	3.433PheLeu: 3.433 ± 0.036	0.756PheMet: 0.756 ± 0.014	1.45PheAsn: 1.45 ± 0.021	2.075PhePro: 2.075 ± 0.025	1.381PheGln: 1.381 ± 0.02	2.07PheArg: 2.07 ± 0.023	3.213PheSer: 3.213 ± 0.027	2.078PheThr: 2.078 ± 0.024	2.234PheVal: 2.234 ± 0.02	0.562PheTrp: 0.562 ± 0.013	1.072PheTyr: 1.072 ± 0.015	0.0PheXaa: 0.0 ± 0.0
Gly	4.884GlyAla: 4.884 ± 0.042	0.797GlyCys: 0.797 ± 0.014	3.713GlyAsp: 3.713 ± 0.032	3.781GlyGlu: 3.781 ± 0.033	2.677GlyPhe: 2.677 ± 0.029	6.117GlyGly: 6.117 ± 0.062	1.607GlyHis: 1.607 ± 0.02	3.533GlyIle: 3.533 ± 0.033	3.629GlyLys: 3.629 ± 0.036	5.569GlyLeu: 5.569 ± 0.037	1.585GlyMet: 1.585 ± 0.02	2.735GlyAsn: 2.735 ± 0.03	3.223GlyPro: 3.223 ± 0.031	2.427GlyGln: 2.427 ± 0.028	4.213GlyArg: 4.213 ± 0.035	5.76GlySer: 5.76 ± 0.043	3.8GlyThr: 3.8 ± 0.039	4.198GlyVal: 4.198 ± 0.038	1.07GlyTrp: 1.07 ± 0.015	2.023GlyTyr: 2.023 ± 0.025	0.0GlyXaa: 0.0 ± 0.0
His	1.791HisAla: 1.791 ± 0.023	0.326HisCys: 0.326 ± 0.009	1.333HisAsp: 1.333 ± 0.017	1.321HisGlu: 1.321 ± 0.019	0.94HisPhe: 0.94 ± 0.015	1.706HisGly: 1.706 ± 0.022	1.004HisHis: 1.004 ± 0.026	1.334HisIle: 1.334 ± 0.018	0.926HisLys: 0.926 ± 0.017	2.302HisLeu: 2.302 ± 0.025	0.469HisMet: 0.469 ± 0.011	0.956HisAsn: 0.956 ± 0.016	1.858HisPro: 1.858 ± 0.025	1.147HisGln: 1.147 ± 0.02	1.631HisArg: 1.631 ± 0.023	2.126HisSer: 2.126 ± 0.027	1.34HisThr: 1.34 ± 0.019	1.369HisVal: 1.369 ± 0.018	0.303HisTrp: 0.303 ± 0.007	0.671HisTyr: 0.671 ± 0.013	0.0HisXaa: 0.0 ± 0.0
Ile	3.988IleAla: 3.988 ± 0.034	0.795IleCys: 0.795 ± 0.014	2.953IleAsp: 2.953 ± 0.028	2.975IleGlu: 2.975 ± 0.031	2.124IlePhe: 2.124 ± 0.027	3.066IleGly: 3.066 ± 0.03	1.328IleHis: 1.328 ± 0.017	2.659IleIle: 2.659 ± 0.034	2.303IleLys: 2.303 ± 0.023	4.829IleLeu: 4.829 ± 0.041	1.012IleMet: 1.012 ± 0.015	1.942IleAsn: 1.942 ± 0.022	3.403IlePro: 3.403 ± 0.029	1.966IleGln: 1.966 ± 0.02	2.957IleArg: 2.957 ± 0.025	4.54IleSer: 4.54 ± 0.036	2.892IleThr: 2.892 ± 0.025	3.082IleVal: 3.082 ± 0.032	0.686IleTrp: 0.686 ± 0.012	1.478IleTyr: 1.478 ± 0.02	0.0IleXaa: 0.0 ± 0.0
Lys	4.008LysAla: 4.008 ± 0.039	0.563LysCys: 0.563 ± 0.012	2.706LysAsp: 2.706 ± 0.026	3.472LysGlu: 3.472 ± 0.035	1.63LysPhe: 1.63 ± 0.02	3.068LysGly: 3.068 ± 0.029	1.22LysHis: 1.22 ± 0.017	2.546LysIle: 2.546 ± 0.026	3.491LysLys: 3.491 ± 0.048	4.387LysLeu: 4.387 ± 0.04	1.06LysMet: 1.06 ± 0.016	1.974LysAsn: 1.974 ± 0.02	2.997LysPro: 2.997 ± 0.032	2.004LysGln: 2.004 ± 0.023	3.776LysArg: 3.776 ± 0.039	3.882LysSer: 3.882 ± 0.032	2.795LysThr: 2.795 ± 0.03	2.785LysVal: 2.785 ± 0.026	0.646LysTrp: 0.646 ± 0.015	1.463LysTyr: 1.463 ± 0.021	0.0LysXaa: 0.0 ± 0.0
Leu	7.185LeuAla: 7.185 ± 0.048	1.177LeuCys: 1.177 ± 0.018	5.07LeuAsp: 5.07 ± 0.035	5.556LeuGlu: 5.556 ± 0.047	3.284LeuPhe: 3.284 ± 0.035	5.539LeuGly: 5.539 ± 0.042	2.313LeuHis: 2.313 ± 0.026	4.022LeuIle: 4.022 ± 0.037	4.54LeuLys: 4.54 ± 0.038	8.362LeuLeu: 8.362 ± 0.068	1.689LeuMet: 1.689 ± 0.02	3.399LeuAsn: 3.399 ± 0.027	5.584LeuPro: 5.584 ± 0.043	3.816LeuGln: 3.816 ± 0.036	5.858LeuArg: 5.858 ± 0.043	7.755LeuSer: 7.755 ± 0.048	4.753LeuThr: 4.753 ± 0.031	5.065LeuVal: 5.065 ± 0.049	1.075LeuTrp: 1.075 ± 0.017	2.295LeuTyr: 2.295 ± 0.027	0.0LeuXaa: 0.0 ± 0.0
Met	2.063MetAla: 2.063 ± 0.025	0.24MetCys: 0.24 ± 0.006	1.228MetAsp: 1.228 ± 0.021	1.353MetGlu: 1.353 ± 0.017	0.707MetPhe: 0.707 ± 0.015	1.414MetGly: 1.414 ± 0.02	0.436MetHis: 0.436 ± 0.012	0.999MetIle: 0.999 ± 0.016	1.105MetLys: 1.105 ± 0.014	1.76MetLeu: 1.76 ± 0.023	0.527MetMet: 0.527 ± 0.012	0.839MetAsn: 0.839 ± 0.015	1.189MetPro: 1.189 ± 0.018	0.813MetGln: 0.813 ± 0.013	1.219MetArg: 1.219 ± 0.018	1.78MetSer: 1.78 ± 0.018	1.244MetThr: 1.244 ± 0.02	1.222MetVal: 1.222 ± 0.016	0.248MetTrp: 0.248 ± 0.007	0.467MetTyr: 0.467 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	3.105AsnAla: 3.105 ± 0.029	0.474AsnCys: 0.474 ± 0.012	2.189AsnAsp: 2.189 ± 0.024	2.286AsnGlu: 2.286 ± 0.026	1.414AsnPhe: 1.414 ± 0.019	3.126AsnGly: 3.126 ± 0.033	0.994AsnHis: 0.994 ± 0.015	2.31AsnIle: 2.31 ± 0.022	1.742AsnLys: 1.742 ± 0.021	3.448AsnLeu: 3.448 ± 0.035	0.863AsnMet: 0.863 ± 0.014	2.058AsnAsn: 2.058 ± 0.034	2.729AsnPro: 2.729 ± 0.027	1.477AsnGln: 1.477 ± 0.019	2.2AsnArg: 2.2 ± 0.023	3.285AsnSer: 3.285 ± 0.031	2.341AsnThr: 2.341 ± 0.023	2.351AsnVal: 2.351 ± 0.024	0.494AsnTrp: 0.494 ± 0.012	1.061AsnTyr: 1.061 ± 0.015	0.0AsnXaa: 0.0 ± 0.0
Pro	4.97ProAla: 4.97 ± 0.044	0.533ProCys: 0.533 ± 0.013	3.21ProAsp: 3.21 ± 0.032	3.74ProGlu: 3.74 ± 0.034	2.13ProPhe: 2.13 ± 0.023	3.891ProGly: 3.891 ± 0.035	1.52ProHis: 1.52 ± 0.019	2.731ProIle: 2.731 ± 0.026	2.778ProLys: 2.778 ± 0.032	4.991ProLeu: 4.991 ± 0.035	1.028ProMet: 1.028 ± 0.019	2.526ProAsn: 2.526 ± 0.027	5.973ProPro: 5.973 ± 0.076	2.702ProGln: 2.702 ± 0.035	3.546ProArg: 3.546 ± 0.032	6.705ProSer: 6.705 ± 0.061	4.257ProThr: 4.257 ± 0.037	3.444ProVal: 3.444 ± 0.031	0.667ProTrp: 0.667 ± 0.014	1.515ProTyr: 1.515 ± 0.02	0.0ProXaa: 0.0 ± 0.0
Gln	3.125GlnAla: 3.125 ± 0.031	0.438GlnCys: 0.438 ± 0.01	1.941GlnAsp: 1.941 ± 0.024	2.381GlnGlu: 2.381 ± 0.025	1.309GlnPhe: 1.309 ± 0.017	2.289GlnGly: 2.289 ± 0.023	1.234GlnHis: 1.234 ± 0.025	1.949GlnIle: 1.949 ± 0.021	2.146GlnLys: 2.146 ± 0.025	3.546GlnLeu: 3.546 ± 0.032	0.843GlnMet: 0.843 ± 0.015	1.741GlnAsn: 1.741 ± 0.022	2.778GlnPro: 2.778 ± 0.034	3.025GlnGln: 3.025 ± 0.067	2.77GlnArg: 2.77 ± 0.031	3.294GlnSer: 3.294 ± 0.031	2.3GlnThr: 2.3 ± 0.026	1.998GlnVal: 1.998 ± 0.024	0.477GlnTrp: 0.477 ± 0.011	1.108GlnTyr: 1.108 ± 0.019	0.0GlnXaa: 0.0 ± 0.0
Arg	4.607ArgAla: 4.607 ± 0.041	0.734ArgCys: 0.734 ± 0.014	3.442ArgAsp: 3.442 ± 0.03	4.094ArgGlu: 4.094 ± 0.041	2.147ArgPhe: 2.147 ± 0.021	3.949ArgGly: 3.949 ± 0.042	1.627ArgHis: 1.627 ± 0.023	3.066ArgIle: 3.066 ± 0.027	3.802ArgLys: 3.802 ± 0.032	5.469ArgLeu: 5.469 ± 0.047	1.323ArgMet: 1.323 ± 0.019	2.536ArgAsn: 2.536 ± 0.026	3.614ArgPro: 3.614 ± 0.037	2.741ArgGln: 2.741 ± 0.028	5.419ArgArg: 5.419 ± 0.049	5.117ArgSer: 5.117 ± 0.049	3.371ArgThr: 3.371 ± 0.027	3.361ArgVal: 3.361 ± 0.029	0.865ArgTrp: 0.865 ± 0.016	1.692ArgTyr: 1.692 ± 0.019	0.0ArgXaa: 0.0 ± 0.0
Ser	6.599SerAla: 6.599 ± 0.043	0.891SerCys: 0.891 ± 0.015	4.315SerAsp: 4.315 ± 0.036	4.292SerGlu: 4.292 ± 0.036	3.111SerPhe: 3.111 ± 0.028	5.701SerGly: 5.701 ± 0.038	2.207SerHis: 2.207 ± 0.027	4.266SerIle: 4.266 ± 0.034	4.116SerLys: 4.116 ± 0.037	7.539SerLeu: 7.539 ± 0.045	1.735SerMet: 1.735 ± 0.018	3.519SerAsn: 3.519 ± 0.032	6.307SerPro: 6.307 ± 0.063	3.512SerGln: 3.512 ± 0.029	5.546SerArg: 5.546 ± 0.051	10.2SerSer: 10.2 ± 0.08	6.028SerThr: 6.028 ± 0.045	4.49SerVal: 4.49 ± 0.036	1.048SerTrp: 1.048 ± 0.015	2.065SerTyr: 2.065 ± 0.023	0.0SerXaa: 0.0 ± 0.0
Thr	4.961ThrAla: 4.961 ± 0.038	0.715ThrCys: 0.715 ± 0.016	2.848ThrAsp: 2.848 ± 0.029	3.076ThrGlu: 3.076 ± 0.027	2.188ThrPhe: 2.188 ± 0.025	4.025ThrGly: 4.025 ± 0.035	1.367ThrHis: 1.367 ± 0.018	3.135ThrIle: 3.135 ± 0.031	2.695ThrLys: 2.695 ± 0.029	5.133ThrLeu: 5.133 ± 0.043	1.104ThrMet: 1.104 ± 0.015	2.264ThrAsn: 2.264 ± 0.025	4.518ThrPro: 4.518 ± 0.042	2.089ThrGln: 2.089 ± 0.023	3.18ThrArg: 3.18 ± 0.03	5.733ThrSer: 5.733 ± 0.043	4.613ThrThr: 4.613 ± 0.048	3.477ThrVal: 3.477 ± 0.029	0.706ThrTrp: 0.706 ± 0.014	1.508ThrTyr: 1.508 ± 0.018	0.0ThrXaa: 0.0 ± 0.0
Val	4.621ValAla: 4.621 ± 0.038	0.756ValCys: 0.756 ± 0.015	3.636ValAsp: 3.636 ± 0.032	3.813ValGlu: 3.813 ± 0.032	2.271ValPhe: 2.271 ± 0.026	3.873ValGly: 3.873 ± 0.033	1.309ValHis: 1.309 ± 0.019	2.951ValIle: 2.951 ± 0.032	2.938ValLys: 2.938 ± 0.03	5.206ValLeu: 5.206 ± 0.042	1.242ValMet: 1.242 ± 0.018	2.254ValAsn: 2.254 ± 0.024	3.386ValPro: 3.386 ± 0.035	2.186ValGln: 2.186 ± 0.022	3.377ValArg: 3.377 ± 0.028	4.521ValSer: 4.521 ± 0.033	3.257ValThr: 3.257 ± 0.028	3.918ValVal: 3.918 ± 0.043	0.752ValTrp: 0.752 ± 0.014	1.546ValTyr: 1.546 ± 0.017	0.0ValXaa: 0.0 ± 0.0
Trp	0.983TrpAla: 0.983 ± 0.016	0.165TrpCys: 0.165 ± 0.006	0.8TrpAsp: 0.8 ± 0.016	0.82TrpGlu: 0.82 ± 0.014	0.459TrpPhe: 0.459 ± 0.012	0.818TrpGly: 0.818 ± 0.016	0.307TrpHis: 0.307 ± 0.008	0.704TrpIle: 0.704 ± 0.012	0.781TrpLys: 0.781 ± 0.014	1.186TrpLeu: 1.186 ± 0.015	0.33TrpMet: 0.33 ± 0.009	0.585TrpAsn: 0.585 ± 0.013	0.522TrpPro: 0.522 ± 0.012	0.488TrpGln: 0.488 ± 0.011	0.905TrpArg: 0.905 ± 0.016	0.943TrpSer: 0.943 ± 0.014	0.741TrpThr: 0.741 ± 0.014	0.793TrpVal: 0.793 ± 0.013	0.236TrpTrp: 0.236 ± 0.009	0.367TrpTyr: 0.367 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.904TyrAla: 1.904 ± 0.02	0.401TyrCys: 0.401 ± 0.01	1.606TyrAsp: 1.606 ± 0.018	1.486TyrGlu: 1.486 ± 0.022	1.179TyrPhe: 1.179 ± 0.018	1.898TyrGly: 1.898 ± 0.025	0.747TyrHis: 0.747 ± 0.015	1.472TyrIle: 1.472 ± 0.02	1.106TyrLys: 1.106 ± 0.015	2.597TyrLeu: 2.597 ± 0.031	0.588TyrMet: 0.588 ± 0.012	1.071TyrAsn: 1.071 ± 0.016	1.542TyrPro: 1.542 ± 0.021	1.083TyrGln: 1.083 ± 0.016	1.601TyrArg: 1.601 ± 0.018	2.114TyrSer: 2.114 ± 0.025	1.483TyrThr: 1.483 ± 0.019	1.526TyrVal: 1.526 ± 0.021	0.372TyrTrp: 0.372 ± 0.009	0.875TyrTyr: 0.875 ± 0.016	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 8944 proteins (4270530 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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