Amino acid dipepetide frequency for Wenzhou bivalvia virus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
10.989AlaAla: 10.989 ± 0.214
1.047AlaCys: 1.047 ± 0.532
3.663AlaAsp: 3.663 ± 0.205
1.57AlaGlu: 1.57 ± 0.797
3.663AlaPhe: 3.663 ± 1.033
8.896AlaGly: 8.896 ± 2.105
1.57AlaHis: 1.57 ± 0.859
3.14AlaIle: 3.14 ± 0.061
4.71AlaLys: 4.71 ± 0.92
8.373AlaLeu: 8.373 ± 0.113
2.616AlaMet: 2.616 ± 1.155
2.616AlaAsn: 2.616 ± 0.501
4.186AlaPro: 4.186 ± 2.013
2.616AlaGln: 2.616 ± 0.327
2.616AlaArg: 2.616 ± 0.327
6.279AlaSer: 6.279 ± 0.706
2.616AlaThr: 2.616 ± 0.501
9.942AlaVal: 9.942 ± 0.083
2.093AlaTrp: 2.093 ± 1.063
3.663AlaTyr: 3.663 ± 0.205
0.0AlaXaa: 0.0 ± 0.0
Cys
1.57CysAla: 1.57 ± 0.797
0.0CysCys: 0.0 ± 0.0
1.047CysAsp: 1.047 ± 0.532
0.523CysGlu: 0.523 ± 0.266
0.523CysPhe: 0.523 ± 0.266
3.14CysGly: 3.14 ± 1.595
0.523CysHis: 0.523 ± 0.266
0.523CysIle: 0.523 ± 0.562
1.047CysLys: 1.047 ± 0.532
2.616CysLeu: 2.616 ± 1.155
0.0CysMet: 0.0 ± 0.0
1.047CysAsn: 1.047 ± 0.532
0.523CysPro: 0.523 ± 0.266
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
0.523CysSer: 0.523 ± 0.266
1.57CysThr: 1.57 ± 0.031
1.047CysVal: 1.047 ± 0.296
0.0CysTrp: 0.0 ± 0.0
2.093CysTyr: 2.093 ± 0.593
0.0CysXaa: 0.0 ± 0.0
Asp
5.756AspAla: 5.756 ± 1.268
2.093AspCys: 2.093 ± 1.063
3.663AspAsp: 3.663 ± 0.205
1.047AspGlu: 1.047 ± 0.532
1.57AspPhe: 1.57 ± 0.031
6.803AspGly: 6.803 ± 0.144
1.047AspHis: 1.047 ± 0.532
2.093AspIle: 2.093 ± 1.063
4.186AspLys: 4.186 ± 0.357
7.326AspLeu: 7.326 ± 0.409
0.523AspMet: 0.523 ± 0.266
1.047AspAsn: 1.047 ± 0.296
3.663AspPro: 3.663 ± 0.205
2.093AspGln: 2.093 ± 0.593
0.523AspArg: 0.523 ± 0.266
2.616AspSer: 2.616 ± 1.983
4.186AspThr: 4.186 ± 1.185
3.663AspVal: 3.663 ± 1.451
1.047AspTrp: 1.047 ± 0.296
2.093AspTyr: 2.093 ± 1.421
0.0AspXaa: 0.0 ± 0.0
Glu
2.093GluAla: 2.093 ± 0.235
1.047GluCys: 1.047 ± 0.532
3.663GluAsp: 3.663 ± 1.861
4.186GluGlu: 4.186 ± 2.126
1.57GluPhe: 1.57 ± 0.031
3.14GluGly: 3.14 ± 0.061
0.523GluHis: 0.523 ± 0.266
1.047GluIle: 1.047 ± 0.532
2.093GluLys: 2.093 ± 0.235
4.71GluLeu: 4.71 ± 0.736
1.047GluMet: 1.047 ± 0.532
2.093GluAsn: 2.093 ± 0.235
2.093GluPro: 2.093 ± 1.063
2.093GluGln: 2.093 ± 1.063
2.093GluArg: 2.093 ± 1.421
3.14GluSer: 3.14 ± 0.061
4.186GluThr: 4.186 ± 1.299
2.093GluVal: 2.093 ± 0.235
1.57GluTrp: 1.57 ± 0.031
3.14GluTyr: 3.14 ± 0.061
0.0GluXaa: 0.0 ± 0.0
Phe
2.093PheAla: 2.093 ± 0.593
0.0PheCys: 0.0 ± 0.0
2.616PheAsp: 2.616 ± 1.155
1.047PheGlu: 1.047 ± 0.532
2.093PhePhe: 2.093 ± 0.235
2.616PheGly: 2.616 ± 0.501
1.047PheHis: 1.047 ± 0.532
2.616PheIle: 2.616 ± 0.327
1.047PheLys: 1.047 ± 0.532
2.616PheLeu: 2.616 ± 1.155
1.047PheMet: 1.047 ± 0.296
0.523PheAsn: 0.523 ± 0.562
0.523PhePro: 0.523 ± 0.266
1.047PheGln: 1.047 ± 0.296
3.663PheArg: 3.663 ± 0.623
3.663PheSer: 3.663 ± 1.861
2.093PheThr: 2.093 ± 0.235
2.093PheVal: 2.093 ± 0.235
0.523PheTrp: 0.523 ± 0.266
2.093PheTyr: 2.093 ± 0.235
0.0PheXaa: 0.0 ± 0.0
Gly
9.942GlyAla: 9.942 ± 2.401
1.047GlyCys: 1.047 ± 0.296
4.71GlyAsp: 4.71 ± 0.736
3.14GlyGlu: 3.14 ± 0.889
3.14GlyPhe: 3.14 ± 0.061
0.523GlyGly: 0.523 ± 0.266
2.093GlyHis: 2.093 ± 1.063
2.616GlyIle: 2.616 ± 1.329
3.14GlyLys: 3.14 ± 0.889
9.942GlyLeu: 9.942 ± 0.745
2.093GlyMet: 2.093 ± 1.063
1.57GlyAsn: 1.57 ± 0.859
4.71GlyPro: 4.71 ± 0.736
3.14GlyGln: 3.14 ± 0.767
6.803GlyArg: 6.803 ± 1.8
2.616GlySer: 2.616 ± 0.327
4.71GlyThr: 4.71 ± 0.092
3.663GlyVal: 3.663 ± 1.033
0.523GlyTrp: 0.523 ± 0.266
2.616GlyTyr: 2.616 ± 0.501
0.0GlyXaa: 0.0 ± 0.0
His
3.663HisAla: 3.663 ± 1.451
0.523HisCys: 0.523 ± 0.266
1.57HisAsp: 1.57 ± 0.797
0.523HisGlu: 0.523 ± 0.266
1.047HisPhe: 1.047 ± 0.532
1.047HisGly: 1.047 ± 0.296
2.093HisHis: 2.093 ± 0.235
1.57HisIle: 1.57 ± 0.031
0.0HisLys: 0.0 ± 0.0
1.57HisLeu: 1.57 ± 0.031
0.523HisMet: 0.523 ± 0.266
0.523HisAsn: 0.523 ± 0.266
1.57HisPro: 1.57 ± 0.031
1.047HisGln: 1.047 ± 0.296
2.616HisArg: 2.616 ± 1.329
1.57HisSer: 1.57 ± 0.859
1.57HisThr: 1.57 ± 0.859
1.047HisVal: 1.047 ± 0.532
1.57HisTrp: 1.57 ± 0.031
0.523HisTyr: 0.523 ± 0.266
0.0HisXaa: 0.0 ± 0.0
Ile
5.233IleAla: 5.233 ± 1.002
2.093IleCys: 2.093 ± 0.593
2.093IleAsp: 2.093 ± 0.235
5.233IleGlu: 5.233 ± 1.002
2.093IlePhe: 2.093 ± 0.235
0.523IleGly: 0.523 ± 0.266
0.523IleHis: 0.523 ± 0.266
2.616IleIle: 2.616 ± 0.501
2.093IleLys: 2.093 ± 0.235
3.14IleLeu: 3.14 ± 0.889
2.093IleMet: 2.093 ± 1.063
1.047IleAsn: 1.047 ± 0.532
2.616IlePro: 2.616 ± 1.983
1.047IleGln: 1.047 ± 0.532
2.093IleArg: 2.093 ± 0.593
2.616IleSer: 2.616 ± 0.501
2.616IleThr: 2.616 ± 0.327
1.57IleVal: 1.57 ± 0.797
0.0IleTrp: 0.0 ± 0.0
0.523IleTyr: 0.523 ± 0.266
0.0IleXaa: 0.0 ± 0.0
Lys
2.616LysAla: 2.616 ± 0.327
1.047LysCys: 1.047 ± 0.296
1.57LysAsp: 1.57 ± 0.031
3.14LysGlu: 3.14 ± 1.717
2.616LysPhe: 2.616 ± 0.327
7.326LysGly: 7.326 ± 0.419
2.093LysHis: 2.093 ± 1.063
1.57LysIle: 1.57 ± 0.797
4.186LysLys: 4.186 ± 1.299
3.14LysLeu: 3.14 ± 0.767
2.616LysMet: 2.616 ± 1.213
2.093LysAsn: 2.093 ± 0.593
3.14LysPro: 3.14 ± 0.767
3.14LysGln: 3.14 ± 0.061
4.71LysArg: 4.71 ± 1.564
3.14LysSer: 3.14 ± 0.889
1.57LysThr: 1.57 ± 0.031
3.663LysVal: 3.663 ± 1.033
1.047LysTrp: 1.047 ± 0.532
1.57LysTyr: 1.57 ± 0.031
0.0LysXaa: 0.0 ± 0.0
Leu
6.803LeuAla: 6.803 ± 0.144
1.57LeuCys: 1.57 ± 0.859
9.942LeuAsp: 9.942 ± 4.057
6.803LeuGlu: 6.803 ± 2.628
3.14LeuPhe: 3.14 ± 0.061
6.279LeuGly: 6.279 ± 0.706
2.616LeuHis: 2.616 ± 0.327
4.186LeuIle: 4.186 ± 0.357
6.803LeuLys: 6.803 ± 0.972
6.279LeuLeu: 6.279 ± 0.95
1.57LeuMet: 1.57 ± 0.797
4.71LeuAsn: 4.71 ± 1.748
8.373LeuPro: 8.373 ± 0.715
3.14LeuGln: 3.14 ± 0.061
2.616LeuArg: 2.616 ± 0.327
6.803LeuSer: 6.803 ± 0.684
5.233LeuThr: 5.233 ± 0.654
6.803LeuVal: 6.803 ± 1.512
1.047LeuTrp: 1.047 ± 0.532
1.57LeuTyr: 1.57 ± 0.031
0.0LeuXaa: 0.0 ± 0.0
Met
2.616MetAla: 2.616 ± 1.329
0.0MetCys: 0.0 ± 0.0
1.57MetAsp: 1.57 ± 0.797
1.57MetGlu: 1.57 ± 0.031
0.523MetPhe: 0.523 ± 0.266
2.616MetGly: 2.616 ± 1.329
0.0MetHis: 0.0 ± 0.0
1.57MetIle: 1.57 ± 0.797
1.57MetLys: 1.57 ± 0.031
4.186MetLeu: 4.186 ± 0.357
0.0MetMet: 0.0 ± 0.0
0.523MetAsn: 0.523 ± 0.266
1.047MetPro: 1.047 ± 0.532
0.523MetGln: 0.523 ± 0.266
2.093MetArg: 2.093 ± 0.235
2.093MetSer: 2.093 ± 1.421
1.047MetThr: 1.047 ± 0.296
2.616MetVal: 2.616 ± 0.327
0.523MetTrp: 0.523 ± 0.266
1.047MetTyr: 1.047 ± 0.532
0.0MetXaa: 0.0 ± 0.0
Asn
2.093AsnAla: 2.093 ± 0.593
1.047AsnCys: 1.047 ± 0.296
0.523AsnAsp: 0.523 ± 0.562
2.093AsnGlu: 2.093 ± 0.235
0.0AsnPhe: 0.0 ± 0.0
2.616AsnGly: 2.616 ± 0.501
0.523AsnHis: 0.523 ± 0.562
2.616AsnIle: 2.616 ± 0.327
3.663AsnLys: 3.663 ± 0.623
4.186AsnLeu: 4.186 ± 0.471
0.523AsnMet: 0.523 ± 0.562
2.616AsnAsn: 2.616 ± 1.983
3.14AsnPro: 3.14 ± 1.717
0.0AsnGln: 0.0 ± 0.0
1.57AsnArg: 1.57 ± 0.797
1.57AsnSer: 1.57 ± 0.859
2.093AsnThr: 2.093 ± 0.235
3.663AsnVal: 3.663 ± 0.623
1.57AsnTrp: 1.57 ± 0.031
0.523AsnTyr: 0.523 ± 0.266
0.0AsnXaa: 0.0 ± 0.0
Pro
7.326ProAla: 7.326 ± 0.409
0.523ProCys: 0.523 ± 0.266
5.233ProAsp: 5.233 ± 0.174
3.14ProGlu: 3.14 ± 0.767
2.616ProPhe: 2.616 ± 1.155
5.233ProGly: 5.233 ± 0.654
0.523ProHis: 0.523 ± 0.266
1.047ProIle: 1.047 ± 0.296
4.186ProLys: 4.186 ± 1.299
3.14ProLeu: 3.14 ± 0.061
3.14ProMet: 3.14 ± 0.889
1.57ProAsn: 1.57 ± 0.859
8.896ProPro: 8.896 ± 2.035
1.57ProGln: 1.57 ± 0.797
3.663ProArg: 3.663 ± 1.033
3.663ProSer: 3.663 ± 0.205
4.71ProThr: 4.71 ± 0.092
4.71ProVal: 4.71 ± 0.92
1.57ProTrp: 1.57 ± 0.031
3.14ProTyr: 3.14 ± 0.767
0.0ProXaa: 0.0 ± 0.0
Gln
2.616GlnAla: 2.616 ± 0.327
1.047GlnCys: 1.047 ± 0.532
0.523GlnAsp: 0.523 ± 0.266
2.616GlnGlu: 2.616 ± 0.327
0.523GlnPhe: 0.523 ± 0.266
1.57GlnGly: 1.57 ± 0.797
1.047GlnHis: 1.047 ± 0.296
1.57GlnIle: 1.57 ± 0.797
3.14GlnLys: 3.14 ± 0.889
2.093GlnLeu: 2.093 ± 0.235
0.523GlnMet: 0.523 ± 0.266
1.57GlnAsn: 1.57 ± 0.859
2.616GlnPro: 2.616 ± 0.501
0.0GlnGln: 0.0 ± 0.0
0.0GlnArg: 0.0 ± 0.0
2.093GlnSer: 2.093 ± 0.593
3.14GlnThr: 3.14 ± 0.061
1.57GlnVal: 1.57 ± 0.031
0.523GlnTrp: 0.523 ± 0.266
1.047GlnTyr: 1.047 ± 0.532
0.0GlnXaa: 0.0 ± 0.0
Arg
5.233ArgAla: 5.233 ± 1.002
0.523ArgCys: 0.523 ± 0.562
2.616ArgAsp: 2.616 ± 0.501
2.093ArgGlu: 2.093 ± 1.063
2.616ArgPhe: 2.616 ± 0.501
4.71ArgGly: 4.71 ± 0.92
0.523ArgHis: 0.523 ± 0.266
2.093ArgIle: 2.093 ± 1.421
2.093ArgLys: 2.093 ± 0.235
7.326ArgLeu: 7.326 ± 0.419
2.093ArgMet: 2.093 ± 0.194
2.616ArgAsn: 2.616 ± 1.329
2.616ArgPro: 2.616 ± 0.501
2.616ArgGln: 2.616 ± 0.501
3.14ArgArg: 3.14 ± 1.595
2.093ArgSer: 2.093 ± 0.235
5.233ArgThr: 5.233 ± 1.482
3.663ArgVal: 3.663 ± 0.205
0.0ArgTrp: 0.0 ± 0.0
1.57ArgTyr: 1.57 ± 1.687
0.0ArgXaa: 0.0 ± 0.0
Ser
4.71SerAla: 4.71 ± 1.748
1.57SerCys: 1.57 ± 0.797
2.616SerAsp: 2.616 ± 0.501
1.57SerGlu: 1.57 ± 0.797
0.523SerPhe: 0.523 ± 0.562
5.233SerGly: 5.233 ± 0.174
1.047SerHis: 1.047 ± 0.296
2.616SerIle: 2.616 ± 0.501
2.616SerLys: 2.616 ± 0.501
6.279SerLeu: 6.279 ± 1.778
2.093SerMet: 2.093 ± 1.063
3.663SerAsn: 3.663 ± 0.623
3.663SerPro: 3.663 ± 1.033
1.57SerGln: 1.57 ± 0.031
6.279SerArg: 6.279 ± 0.95
2.093SerSer: 2.093 ± 0.593
4.186SerThr: 4.186 ± 2.841
4.71SerVal: 4.71 ± 1.748
0.523SerTrp: 0.523 ± 0.266
2.616SerTyr: 2.616 ± 0.501
0.0SerXaa: 0.0 ± 0.0
Thr
4.186ThrAla: 4.186 ± 1.185
0.0ThrCys: 0.0 ± 0.0
3.14ThrAsp: 3.14 ± 0.061
1.047ThrGlu: 1.047 ± 0.296
3.14ThrPhe: 3.14 ± 0.889
2.093ThrGly: 2.093 ± 1.421
3.663ThrHis: 3.663 ± 0.205
6.279ThrIle: 6.279 ± 0.95
1.57ThrLys: 1.57 ± 0.031
7.326ThrLeu: 7.326 ± 1.247
1.57ThrMet: 1.57 ± 0.797
2.093ThrAsn: 2.093 ± 0.235
5.233ThrPro: 5.233 ± 1.83
1.57ThrGln: 1.57 ± 0.031
2.093ThrArg: 2.093 ± 0.593
4.71ThrSer: 4.71 ± 0.092
2.093ThrThr: 2.093 ± 0.235
5.756ThrVal: 5.756 ± 2.044
1.57ThrTrp: 1.57 ± 0.031
2.093ThrTyr: 2.093 ± 1.421
0.0ThrXaa: 0.0 ± 0.0
Val
4.71ValAla: 4.71 ± 0.092
1.047ValCys: 1.047 ± 0.532
3.663ValAsp: 3.663 ± 2.279
3.14ValGlu: 3.14 ± 1.595
1.57ValPhe: 1.57 ± 0.797
6.279ValGly: 6.279 ± 2.362
2.616ValHis: 2.616 ± 1.155
1.57ValIle: 1.57 ± 0.797
3.14ValLys: 3.14 ± 0.061
7.326ValLeu: 7.326 ± 2.074
2.093ValMet: 2.093 ± 0.593
2.093ValAsn: 2.093 ± 1.421
6.803ValPro: 6.803 ± 0.972
1.57ValGln: 1.57 ± 0.859
6.279ValArg: 6.279 ± 0.95
5.233ValSer: 5.233 ± 0.654
4.71ValThr: 4.71 ± 0.092
3.14ValVal: 3.14 ± 0.889
0.523ValTrp: 0.523 ± 0.266
1.57ValTyr: 1.57 ± 0.859
0.0ValXaa: 0.0 ± 0.0
Trp
0.523TrpAla: 0.523 ± 0.266
0.523TrpCys: 0.523 ± 0.266
0.523TrpAsp: 0.523 ± 0.562
1.57TrpGlu: 1.57 ± 0.031
1.047TrpPhe: 1.047 ± 0.296
1.047TrpGly: 1.047 ± 0.296
0.523TrpHis: 0.523 ± 0.266
0.523TrpIle: 0.523 ± 0.266
1.57TrpLys: 1.57 ± 0.797
2.616TrpLeu: 2.616 ± 1.329
1.047TrpMet: 1.047 ± 0.532
0.0TrpAsn: 0.0 ± 0.0
1.047TrpPro: 1.047 ± 0.296
0.523TrpGln: 0.523 ± 0.266
0.523TrpArg: 0.523 ± 0.266
1.047TrpSer: 1.047 ± 0.296
1.57TrpThr: 1.57 ± 0.797
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.093TyrAla: 2.093 ± 0.235
1.57TyrCys: 1.57 ± 0.797
2.093TyrAsp: 2.093 ± 0.235
1.57TyrGlu: 1.57 ± 0.031
1.047TyrPhe: 1.047 ± 0.296
1.047TyrGly: 1.047 ± 0.532
1.57TyrHis: 1.57 ± 0.859
0.0TyrIle: 0.0 ± 0.0
3.14TyrLys: 3.14 ± 1.595
2.093TyrLeu: 2.093 ± 0.235
0.0TyrMet: 0.0 ± 0.0
2.616TyrAsn: 2.616 ± 0.327
3.14TyrPro: 3.14 ± 0.889
0.523TyrGln: 0.523 ± 0.562
2.616TyrArg: 2.616 ± 1.983
2.616TyrSer: 2.616 ± 0.501
2.093TyrThr: 2.093 ± 2.249
3.663TyrVal: 3.663 ± 1.033
0.0TyrTrp: 0.0 ± 0.0
2.616TyrTyr: 2.616 ± 1.155
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1912 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski