Amino acid dipepetide frequency for Burkholderia phage BcepMu (isolate -/United States/Summer/2002) (Bacteriophage BcepMu)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
19.376AlaAla: 19.376 ± 2.108
1.09AlaCys: 1.09 ± 0.35
9.394AlaAsp: 9.394 ± 0.855
6.962AlaGlu: 6.962 ± 1.001
4.194AlaPhe: 4.194 ± 0.732
11.156AlaGly: 11.156 ± 1.258
1.258AlaHis: 1.258 ± 0.323
5.62AlaIle: 5.62 ± 0.762
5.536AlaLys: 5.536 ± 0.685
10.904AlaLeu: 10.904 ± 0.882
2.936AlaMet: 2.936 ± 0.424
3.691AlaAsn: 3.691 ± 0.545
4.949AlaPro: 4.949 ± 0.811
4.529AlaGln: 4.529 ± 0.538
7.968AlaArg: 7.968 ± 0.779
6.039AlaSer: 6.039 ± 0.778
8.22AlaThr: 8.22 ± 0.95
9.059AlaVal: 9.059 ± 0.739
1.09AlaTrp: 1.09 ± 0.262
3.187AlaTyr: 3.187 ± 0.566
0.0AlaXaa: 0.0 ± 0.0
Cys
0.587CysAla: 0.587 ± 0.241
0.084CysCys: 0.084 ± 0.089
0.168CysAsp: 0.168 ± 0.114
0.839CysGlu: 0.839 ± 0.248
0.336CysPhe: 0.336 ± 0.155
0.503CysGly: 0.503 ± 0.191
0.084CysHis: 0.084 ± 0.107
0.0CysIle: 0.0 ± 0.0
0.252CysLys: 0.252 ± 0.151
0.671CysLeu: 0.671 ± 0.26
0.168CysMet: 0.168 ± 0.115
0.084CysAsn: 0.084 ± 0.086
0.168CysPro: 0.168 ± 0.128
0.084CysGln: 0.084 ± 0.069
0.671CysArg: 0.671 ± 0.33
0.336CysSer: 0.336 ± 0.149
0.336CysThr: 0.336 ± 0.176
0.923CysVal: 0.923 ± 0.301
0.084CysTrp: 0.084 ± 0.079
0.084CysTyr: 0.084 ± 0.073
0.0CysXaa: 0.0 ± 0.0
Asp
9.059AspAla: 9.059 ± 0.833
0.587AspCys: 0.587 ± 0.222
3.104AspAsp: 3.104 ± 0.608
4.026AspGlu: 4.026 ± 0.467
1.929AspPhe: 1.929 ± 0.389
4.781AspGly: 4.781 ± 0.666
1.007AspHis: 1.007 ± 0.298
3.355AspIle: 3.355 ± 0.537
1.761AspLys: 1.761 ± 0.367
5.368AspLeu: 5.368 ± 0.601
1.342AspMet: 1.342 ± 0.375
1.51AspAsn: 1.51 ± 0.367
3.104AspPro: 3.104 ± 0.528
2.516AspGln: 2.516 ± 0.386
3.942AspArg: 3.942 ± 0.511
2.432AspSer: 2.432 ± 0.427
2.684AspThr: 2.684 ± 0.494
4.697AspVal: 4.697 ± 0.798
1.007AspTrp: 1.007 ± 0.34
1.845AspTyr: 1.845 ± 0.423
0.0AspXaa: 0.0 ± 0.0
Glu
6.039GluAla: 6.039 ± 0.894
0.419GluCys: 0.419 ± 0.183
2.6GluAsp: 2.6 ± 0.52
3.02GluGlu: 3.02 ± 0.478
2.265GluPhe: 2.265 ± 0.431
2.684GluGly: 2.684 ± 0.439
2.265GluHis: 2.265 ± 0.542
3.02GluIle: 3.02 ± 0.554
2.013GluLys: 2.013 ± 0.457
7.381GluLeu: 7.381 ± 0.736
1.174GluMet: 1.174 ± 0.338
1.342GluAsn: 1.342 ± 0.323
2.013GluPro: 2.013 ± 0.377
3.271GluGln: 3.271 ± 0.44
5.033GluArg: 5.033 ± 0.773
3.355GluSer: 3.355 ± 0.592
3.104GluThr: 3.104 ± 0.468
3.607GluVal: 3.607 ± 0.53
0.419GluTrp: 0.419 ± 0.17
1.594GluTyr: 1.594 ± 0.36
0.0GluXaa: 0.0 ± 0.0
Phe
4.11PheAla: 4.11 ± 0.565
0.084PheCys: 0.084 ± 0.077
2.013PheAsp: 2.013 ± 0.55
1.929PheGlu: 1.929 ± 0.338
0.755PhePhe: 0.755 ± 0.212
4.781PheGly: 4.781 ± 0.731
0.419PheHis: 0.419 ± 0.167
1.342PheIle: 1.342 ± 0.386
1.51PheLys: 1.51 ± 0.38
1.678PheLeu: 1.678 ± 0.513
0.839PheMet: 0.839 ± 0.337
1.007PheAsn: 1.007 ± 0.299
1.007PhePro: 1.007 ± 0.325
1.09PheGln: 1.09 ± 0.303
2.265PheArg: 2.265 ± 0.403
2.6PheSer: 2.6 ± 0.504
1.678PheThr: 1.678 ± 0.3
1.761PheVal: 1.761 ± 0.394
0.587PheTrp: 0.587 ± 0.229
0.839PheTyr: 0.839 ± 0.246
0.0PheXaa: 0.0 ± 0.0
Gly
10.065GlyAla: 10.065 ± 1.095
0.503GlyCys: 0.503 ± 0.182
4.278GlyAsp: 4.278 ± 0.509
5.284GlyGlu: 5.284 ± 0.804
2.6GlyPhe: 2.6 ± 0.392
6.039GlyGly: 6.039 ± 0.808
1.258GlyHis: 1.258 ± 0.282
2.768GlyIle: 2.768 ± 0.784
4.11GlyLys: 4.11 ± 0.682
5.955GlyLeu: 5.955 ± 0.737
2.432GlyMet: 2.432 ± 0.633
3.355GlyAsn: 3.355 ± 0.512
2.181GlyPro: 2.181 ± 0.477
3.942GlyGln: 3.942 ± 0.491
5.536GlyArg: 5.536 ± 0.965
5.117GlySer: 5.117 ± 1.081
3.775GlyThr: 3.775 ± 0.811
7.214GlyVal: 7.214 ± 0.769
1.426GlyTrp: 1.426 ± 0.383
3.271GlyTyr: 3.271 ± 0.465
0.0GlyXaa: 0.0 ± 0.0
His
2.097HisAla: 2.097 ± 0.52
0.168HisCys: 0.168 ± 0.118
1.09HisAsp: 1.09 ± 0.446
0.755HisGlu: 0.755 ± 0.238
0.503HisPhe: 0.503 ± 0.162
1.594HisGly: 1.594 ± 0.449
0.252HisHis: 0.252 ± 0.146
0.503HisIle: 0.503 ± 0.21
0.755HisLys: 0.755 ± 0.296
1.174HisLeu: 1.174 ± 0.324
0.671HisMet: 0.671 ± 0.203
0.671HisAsn: 0.671 ± 0.37
1.007HisPro: 1.007 ± 0.29
0.755HisGln: 0.755 ± 0.283
0.923HisArg: 0.923 ± 0.311
0.503HisSer: 0.503 ± 0.176
0.336HisThr: 0.336 ± 0.147
1.678HisVal: 1.678 ± 0.364
0.503HisTrp: 0.503 ± 0.216
0.168HisTyr: 0.168 ± 0.123
0.0HisXaa: 0.0 ± 0.0
Ile
5.955IleAla: 5.955 ± 0.833
0.336IleCys: 0.336 ± 0.162
3.691IleAsp: 3.691 ± 0.567
3.355IleGlu: 3.355 ± 0.528
1.258IlePhe: 1.258 ± 0.338
4.781IleGly: 4.781 ± 0.901
0.587IleHis: 0.587 ± 0.239
1.174IleIle: 1.174 ± 0.259
2.936IleLys: 2.936 ± 0.405
3.271IleLeu: 3.271 ± 0.564
0.839IleMet: 0.839 ± 0.263
1.51IleAsn: 1.51 ± 0.488
1.845IlePro: 1.845 ± 0.45
2.181IleGln: 2.181 ± 0.407
4.11IleArg: 4.11 ± 0.516
1.678IleSer: 1.678 ± 0.34
2.852IleThr: 2.852 ± 0.473
3.104IleVal: 3.104 ± 0.663
0.503IleTrp: 0.503 ± 0.215
1.007IleTyr: 1.007 ± 0.287
0.0IleXaa: 0.0 ± 0.0
Lys
5.788LysAla: 5.788 ± 0.677
0.084LysCys: 0.084 ± 0.095
2.097LysAsp: 2.097 ± 0.43
2.349LysGlu: 2.349 ± 0.48
1.761LysPhe: 1.761 ± 0.345
4.194LysGly: 4.194 ± 0.494
0.671LysHis: 0.671 ± 0.301
1.51LysIle: 1.51 ± 0.386
2.432LysLys: 2.432 ± 0.466
4.697LysLeu: 4.697 ± 0.777
0.419LysMet: 0.419 ± 0.173
1.09LysAsn: 1.09 ± 0.288
1.678LysPro: 1.678 ± 0.443
2.852LysGln: 2.852 ± 0.519
2.349LysArg: 2.349 ± 0.508
2.852LysSer: 2.852 ± 0.49
1.761LysThr: 1.761 ± 0.328
3.439LysVal: 3.439 ± 0.547
0.671LysTrp: 0.671 ± 0.217
0.923LysTyr: 0.923 ± 0.221
0.0LysXaa: 0.0 ± 0.0
Leu
11.575LeuAla: 11.575 ± 0.884
0.587LeuCys: 0.587 ± 0.281
6.375LeuAsp: 6.375 ± 0.945
4.865LeuGlu: 4.865 ± 0.807
1.594LeuPhe: 1.594 ± 0.425
7.214LeuGly: 7.214 ± 1.104
1.007LeuHis: 1.007 ± 0.296
4.278LeuIle: 4.278 ± 0.638
4.362LeuLys: 4.362 ± 0.629
6.626LeuLeu: 6.626 ± 0.909
2.097LeuMet: 2.097 ± 0.57
3.355LeuAsn: 3.355 ± 0.579
4.697LeuPro: 4.697 ± 0.632
3.691LeuGln: 3.691 ± 0.653
7.801LeuArg: 7.801 ± 0.752
6.123LeuSer: 6.123 ± 0.665
6.039LeuThr: 6.039 ± 0.57
6.375LeuVal: 6.375 ± 0.827
0.839LeuTrp: 0.839 ± 0.252
1.845LeuTyr: 1.845 ± 0.368
0.0LeuXaa: 0.0 ± 0.0
Met
2.432MetAla: 2.432 ± 0.44
0.252MetCys: 0.252 ± 0.152
1.007MetAsp: 1.007 ± 0.232
0.755MetGlu: 0.755 ± 0.235
0.755MetPhe: 0.755 ± 0.259
1.678MetGly: 1.678 ± 0.394
0.168MetHis: 0.168 ± 0.125
1.09MetIle: 1.09 ± 0.345
1.007MetLys: 1.007 ± 0.329
2.936MetLeu: 2.936 ± 0.647
0.252MetMet: 0.252 ± 0.135
1.007MetAsn: 1.007 ± 0.268
0.923MetPro: 0.923 ± 0.239
0.671MetGln: 0.671 ± 0.222
2.6MetArg: 2.6 ± 0.34
1.426MetSer: 1.426 ± 0.31
2.097MetThr: 2.097 ± 0.355
1.258MetVal: 1.258 ± 0.287
0.252MetTrp: 0.252 ± 0.121
0.336MetTyr: 0.336 ± 0.171
0.0MetXaa: 0.0 ± 0.0
Asn
4.278AsnAla: 4.278 ± 0.704
0.168AsnCys: 0.168 ± 0.121
0.839AsnAsp: 0.839 ± 0.229
1.007AsnGlu: 1.007 ± 0.27
1.09AsnPhe: 1.09 ± 0.304
3.187AsnGly: 3.187 ± 0.525
0.923AsnHis: 0.923 ± 0.233
1.761AsnIle: 1.761 ± 0.42
1.258AsnLys: 1.258 ± 0.302
3.858AsnLeu: 3.858 ± 0.496
0.923AsnMet: 0.923 ± 0.291
0.252AsnAsn: 0.252 ± 0.141
1.761AsnPro: 1.761 ± 0.383
1.678AsnGln: 1.678 ± 0.495
1.678AsnArg: 1.678 ± 0.362
1.761AsnSer: 1.761 ± 0.511
1.929AsnThr: 1.929 ± 0.366
2.013AsnVal: 2.013 ± 0.449
0.168AsnTrp: 0.168 ± 0.12
0.419AsnTyr: 0.419 ± 0.19
0.0AsnXaa: 0.0 ± 0.0
Pro
4.949ProAla: 4.949 ± 0.779
0.084ProCys: 0.084 ± 0.098
3.439ProAsp: 3.439 ± 0.561
3.187ProGlu: 3.187 ± 0.612
1.845ProPhe: 1.845 ± 0.382
3.104ProGly: 3.104 ± 0.489
0.755ProHis: 0.755 ± 0.233
1.929ProIle: 1.929 ± 0.353
2.181ProLys: 2.181 ± 0.524
3.523ProLeu: 3.523 ± 0.454
1.007ProMet: 1.007 ± 0.289
1.174ProAsn: 1.174 ± 0.332
2.265ProPro: 2.265 ± 0.514
1.174ProGln: 1.174 ± 0.315
2.684ProArg: 2.684 ± 0.468
2.432ProSer: 2.432 ± 0.445
1.929ProThr: 1.929 ± 0.392
4.529ProVal: 4.529 ± 0.706
0.419ProTrp: 0.419 ± 0.191
1.174ProTyr: 1.174 ± 0.279
0.0ProXaa: 0.0 ± 0.0
Gln
6.291GlnAla: 6.291 ± 0.735
0.168GlnCys: 0.168 ± 0.111
1.929GlnAsp: 1.929 ± 0.414
2.349GlnGlu: 2.349 ± 0.465
1.929GlnPhe: 1.929 ± 0.465
2.349GlnGly: 2.349 ± 0.701
0.419GlnHis: 0.419 ± 0.168
2.936GlnIle: 2.936 ± 0.47
1.426GlnLys: 1.426 ± 0.306
4.697GlnLeu: 4.697 ± 0.657
1.174GlnMet: 1.174 ± 0.437
0.755GlnAsn: 0.755 ± 0.213
2.097GlnPro: 2.097 ± 0.514
1.761GlnGln: 1.761 ± 0.433
2.936GlnArg: 2.936 ± 0.469
2.181GlnSer: 2.181 ± 0.429
2.265GlnThr: 2.265 ± 0.445
2.181GlnVal: 2.181 ± 0.393
0.671GlnTrp: 0.671 ± 0.216
1.51GlnTyr: 1.51 ± 0.359
0.0GlnXaa: 0.0 ± 0.0
Arg
8.472ArgAla: 8.472 ± 0.825
0.755ArgCys: 0.755 ± 0.247
4.194ArgAsp: 4.194 ± 0.675
4.529ArgGlu: 4.529 ± 0.848
2.516ArgPhe: 2.516 ± 0.497
3.942ArgGly: 3.942 ± 0.677
2.013ArgHis: 2.013 ± 0.457
3.858ArgIle: 3.858 ± 0.595
2.684ArgLys: 2.684 ± 0.53
5.955ArgLeu: 5.955 ± 0.747
2.013ArgMet: 2.013 ± 0.371
2.097ArgAsn: 2.097 ± 0.46
3.439ArgPro: 3.439 ± 0.591
2.265ArgGln: 2.265 ± 0.479
6.039ArgArg: 6.039 ± 1.049
4.278ArgSer: 4.278 ± 0.544
2.852ArgThr: 2.852 ± 0.432
5.452ArgVal: 5.452 ± 0.621
1.258ArgTrp: 1.258 ± 0.365
2.265ArgTyr: 2.265 ± 0.433
0.0ArgXaa: 0.0 ± 0.0
Ser
7.046SerAla: 7.046 ± 0.822
0.084SerCys: 0.084 ± 0.07
3.187SerAsp: 3.187 ± 0.456
2.516SerGlu: 2.516 ± 0.31
1.845SerPhe: 1.845 ± 0.379
4.194SerGly: 4.194 ± 0.809
0.755SerHis: 0.755 ± 0.302
2.852SerIle: 2.852 ± 0.464
2.432SerLys: 2.432 ± 0.544
4.446SerLeu: 4.446 ± 0.643
1.51SerMet: 1.51 ± 0.296
2.265SerAsn: 2.265 ± 0.441
2.516SerPro: 2.516 ± 0.461
2.013SerGln: 2.013 ± 0.539
3.607SerArg: 3.607 ± 0.6
3.942SerSer: 3.942 ± 0.812
3.775SerThr: 3.775 ± 0.582
4.446SerVal: 4.446 ± 0.688
0.587SerTrp: 0.587 ± 0.257
2.013SerTyr: 2.013 ± 0.434
0.0SerXaa: 0.0 ± 0.0
Thr
7.214ThrAla: 7.214 ± 0.986
0.168ThrCys: 0.168 ± 0.118
3.523ThrAsp: 3.523 ± 0.749
2.349ThrGlu: 2.349 ± 0.574
1.845ThrPhe: 1.845 ± 0.524
4.865ThrGly: 4.865 ± 0.649
0.839ThrHis: 0.839 ± 0.26
3.271ThrIle: 3.271 ± 0.684
2.013ThrLys: 2.013 ± 0.484
6.71ThrLeu: 6.71 ± 0.854
1.007ThrMet: 1.007 ± 0.223
2.349ThrAsn: 2.349 ± 0.511
2.852ThrPro: 2.852 ± 0.355
1.929ThrGln: 1.929 ± 0.45
3.439ThrArg: 3.439 ± 0.485
3.104ThrSer: 3.104 ± 0.6
4.865ThrThr: 4.865 ± 0.939
4.278ThrVal: 4.278 ± 0.615
0.419ThrTrp: 0.419 ± 0.178
1.678ThrTyr: 1.678 ± 0.516
0.0ThrXaa: 0.0 ± 0.0
Val
7.885ValAla: 7.885 ± 0.949
0.419ValCys: 0.419 ± 0.17
5.2ValAsp: 5.2 ± 0.976
4.697ValGlu: 4.697 ± 0.598
1.929ValPhe: 1.929 ± 0.329
6.039ValGly: 6.039 ± 0.81
0.755ValHis: 0.755 ± 0.235
4.446ValIle: 4.446 ± 0.656
3.187ValLys: 3.187 ± 0.48
6.794ValLeu: 6.794 ± 0.78
1.342ValMet: 1.342 ± 0.375
2.181ValAsn: 2.181 ± 0.444
3.775ValPro: 3.775 ± 0.583
3.355ValGln: 3.355 ± 0.483
4.278ValArg: 4.278 ± 0.608
3.858ValSer: 3.858 ± 0.641
6.123ValThr: 6.123 ± 0.581
4.278ValVal: 4.278 ± 0.646
0.839ValTrp: 0.839 ± 0.256
1.761ValTyr: 1.761 ± 0.414
0.0ValXaa: 0.0 ± 0.0
Trp
0.839TrpAla: 0.839 ± 0.309
0.084TrpCys: 0.084 ± 0.076
0.419TrpAsp: 0.419 ± 0.183
0.503TrpGlu: 0.503 ± 0.195
0.671TrpPhe: 0.671 ± 0.223
1.594TrpGly: 1.594 ± 0.382
0.252TrpHis: 0.252 ± 0.168
0.503TrpIle: 0.503 ± 0.177
0.252TrpLys: 0.252 ± 0.132
1.678TrpLeu: 1.678 ± 0.323
0.336TrpMet: 0.336 ± 0.175
0.168TrpAsn: 0.168 ± 0.111
0.252TrpPro: 0.252 ± 0.151
1.09TrpGln: 1.09 ± 0.418
0.923TrpArg: 0.923 ± 0.294
0.923TrpSer: 0.923 ± 0.24
0.671TrpThr: 0.671 ± 0.262
0.755TrpVal: 0.755 ± 0.233
0.419TrpTrp: 0.419 ± 0.172
0.503TrpTyr: 0.503 ± 0.198
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.104TyrAla: 3.104 ± 0.484
0.336TyrCys: 0.336 ± 0.184
1.594TyrAsp: 1.594 ± 0.344
1.342TyrGlu: 1.342 ± 0.279
0.671TyrPhe: 0.671 ± 0.234
2.432TyrGly: 2.432 ± 0.353
0.419TyrHis: 0.419 ± 0.184
0.755TyrIle: 0.755 ± 0.251
1.51TyrLys: 1.51 ± 0.275
3.02TyrLeu: 3.02 ± 0.47
0.336TyrMet: 0.336 ± 0.185
1.09TyrAsn: 1.09 ± 0.293
1.258TyrPro: 1.258 ± 0.321
1.174TyrGln: 1.174 ± 0.295
2.097TyrArg: 2.097 ± 0.346
1.09TyrSer: 1.09 ± 0.311
1.426TyrThr: 1.426 ± 0.394
2.097TyrVal: 2.097 ± 0.363
0.671TyrTrp: 0.671 ± 0.225
0.587TyrTyr: 0.587 ± 0.21
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 53 proteins (11923 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski