Amino acid dipepetide frequency for Hahella chejuensis (strain KCTC 2396)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.361AlaAla: 10.361 ± 0.097	1.073AlaCys: 1.073 ± 0.026	5.309AlaAsp: 5.309 ± 0.058	6.355AlaGlu: 6.355 ± 0.063	3.628AlaPhe: 3.628 ± 0.042	7.171AlaGly: 7.171 ± 0.08	1.959AlaHis: 1.959 ± 0.033	5.263AlaIle: 5.263 ± 0.054	4.031AlaLys: 4.031 ± 0.05	11.3AlaLeu: 11.3 ± 0.107	2.755AlaMet: 2.755 ± 0.042	3.217AlaAsn: 3.217 ± 0.04	4.443AlaPro: 4.443 ± 0.065	4.379AlaGln: 4.379 ± 0.049	5.22AlaArg: 5.22 ± 0.057	5.966AlaSer: 5.966 ± 0.062	4.553AlaThr: 4.553 ± 0.05	6.333AlaVal: 6.333 ± 0.057	1.228AlaTrp: 1.228 ± 0.027	2.799AlaTyr: 2.799 ± 0.042	0.0AlaXaa: 0.0 ± 0.0
Cys	1.063CysAla: 1.063 ± 0.025	0.158CysCys: 0.158 ± 0.009	0.623CysAsp: 0.623 ± 0.015	0.606CysGlu: 0.606 ± 0.019	0.461CysPhe: 0.461 ± 0.016	0.993CysGly: 0.993 ± 0.024	0.269CysHis: 0.269 ± 0.011	0.509CysIle: 0.509 ± 0.018	0.38CysLys: 0.38 ± 0.012	1.137CysLeu: 1.137 ± 0.025	0.216CysMet: 0.216 ± 0.011	0.335CysAsn: 0.335 ± 0.011	0.492CysPro: 0.492 ± 0.019	0.364CysGln: 0.364 ± 0.013	0.679CysArg: 0.679 ± 0.019	0.663CysSer: 0.663 ± 0.019	0.371CysThr: 0.371 ± 0.016	0.702CysVal: 0.702 ± 0.018	0.146CysTrp: 0.146 ± 0.009	0.307CysTyr: 0.307 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	5.936AspAla: 5.936 ± 0.086	0.581AspCys: 0.581 ± 0.019	3.244AspAsp: 3.244 ± 0.058	3.67AspGlu: 3.67 ± 0.049	2.413AspPhe: 2.413 ± 0.032	4.391AspGly: 4.391 ± 0.065	1.152AspHis: 1.152 ± 0.022	3.67AspIle: 3.67 ± 0.04	2.691AspLys: 2.691 ± 0.042	5.656AspLeu: 5.656 ± 0.053	1.448AspMet: 1.448 ± 0.026	2.124AspAsn: 2.124 ± 0.039	2.637AspPro: 2.637 ± 0.05	2.037AspGln: 2.037 ± 0.035	2.985AspArg: 2.985 ± 0.038	3.322AspSer: 3.322 ± 0.049	2.39AspThr: 2.39 ± 0.04	3.868AspVal: 3.868 ± 0.042	0.973AspTrp: 0.973 ± 0.023	2.142AspTyr: 2.142 ± 0.036	0.0AspXaa: 0.0 ± 0.0
Glu	6.133GluAla: 6.133 ± 0.06	0.539GluCys: 0.539 ± 0.016	3.248GluAsp: 3.248 ± 0.046	4.266GluGlu: 4.266 ± 0.056	2.416GluPhe: 2.416 ± 0.037	4.094GluGly: 4.094 ± 0.053	1.453GluHis: 1.453 ± 0.027	3.644GluIle: 3.644 ± 0.049	3.451GluLys: 3.451 ± 0.051	6.865GluLeu: 6.865 ± 0.066	1.576GluMet: 1.576 ± 0.032	2.339GluAsn: 2.339 ± 0.038	2.428GluPro: 2.428 ± 0.042	3.294GluGln: 3.294 ± 0.041	4.301GluArg: 4.301 ± 0.051	3.92GluSer: 3.92 ± 0.041	3.288GluThr: 3.288 ± 0.046	4.174GluVal: 4.174 ± 0.049	0.896GluTrp: 0.896 ± 0.024	1.868GluTyr: 1.868 ± 0.034	0.0GluXaa: 0.0 ± 0.0
Phe	3.392PheAla: 3.392 ± 0.047	0.519PheCys: 0.519 ± 0.016	2.521PheAsp: 2.521 ± 0.03	2.258PheGlu: 2.258 ± 0.035	1.678PhePhe: 1.678 ± 0.03	2.937PheGly: 2.937 ± 0.041	0.853PheHis: 0.853 ± 0.023	2.303PheIle: 2.303 ± 0.036	1.705PheLys: 1.705 ± 0.031	3.555PheLeu: 3.555 ± 0.043	0.94PheMet: 0.94 ± 0.024	1.692PheAsn: 1.692 ± 0.03	1.597PhePro: 1.597 ± 0.027	1.365PheGln: 1.365 ± 0.026	1.939PheArg: 1.939 ± 0.025	3.15PheSer: 3.15 ± 0.043	2.146PheThr: 2.146 ± 0.038	2.617PheVal: 2.617 ± 0.036	0.564PheTrp: 0.564 ± 0.016	1.295PheTyr: 1.295 ± 0.026	0.0PheXaa: 0.0 ± 0.0
Gly	7.231GlyAla: 7.231 ± 0.086	0.913GlyCys: 0.913 ± 0.024	4.72GlyAsp: 4.72 ± 0.074	4.901GlyGlu: 4.901 ± 0.042	3.113GlyPhe: 3.113 ± 0.04	5.983GlyGly: 5.983 ± 0.103	1.486GlyHis: 1.486 ± 0.03	3.21GlyIle: 3.21 ± 0.048	3.511GlyLys: 3.511 ± 0.045	7.382GlyLeu: 7.382 ± 0.068	2.022GlyMet: 2.022 ± 0.034	2.185GlyAsn: 2.185 ± 0.051	2.169GlyPro: 2.169 ± 0.037	2.643GlyGln: 2.643 ± 0.044	4.2GlyArg: 4.2 ± 0.061	4.292GlySer: 4.292 ± 0.063	2.579GlyThr: 2.579 ± 0.054	6.54GlyVal: 6.54 ± 0.069	1.162GlyTrp: 1.162 ± 0.026	2.717GlyTyr: 2.717 ± 0.043	0.0GlyXaa: 0.0 ± 0.0
His	1.775HisAla: 1.775 ± 0.028	0.346HisCys: 0.346 ± 0.013	1.117HisAsp: 1.117 ± 0.02	1.189HisGlu: 1.189 ± 0.027	1.04HisPhe: 1.04 ± 0.024	1.592HisGly: 1.592 ± 0.027	0.628HisHis: 0.628 ± 0.02	1.263HisIle: 1.263 ± 0.024	0.879HisLys: 0.879 ± 0.021	2.196HisLeu: 2.196 ± 0.035	0.545HisMet: 0.545 ± 0.016	0.759HisAsn: 0.759 ± 0.021	1.265HisPro: 1.265 ± 0.024	0.868HisGln: 0.868 ± 0.021	1.341HisArg: 1.341 ± 0.026	1.367HisSer: 1.367 ± 0.028	0.995HisThr: 0.995 ± 0.022	1.221HisVal: 1.221 ± 0.022	0.37HisTrp: 0.37 ± 0.015	0.857HisTyr: 0.857 ± 0.02	0.0HisXaa: 0.0 ± 0.0
Ile	5.654IleAla: 5.654 ± 0.059	0.593IleCys: 0.593 ± 0.017	3.518IleAsp: 3.518 ± 0.04	3.699IleGlu: 3.699 ± 0.042	1.804IlePhe: 1.804 ± 0.036	3.92IleGly: 3.92 ± 0.051	1.133IleHis: 1.133 ± 0.025	2.729IleIle: 2.729 ± 0.047	2.526IleLys: 2.526 ± 0.04	4.701IleLeu: 4.701 ± 0.064	1.089IleMet: 1.089 ± 0.022	2.374IleAsn: 2.374 ± 0.036	2.488IlePro: 2.488 ± 0.039	1.931IleGln: 1.931 ± 0.03	3.101IleArg: 3.101 ± 0.035	3.864IleSer: 3.864 ± 0.049	2.832IleThr: 2.832 ± 0.043	3.494IleVal: 3.494 ± 0.041	0.614IleTrp: 0.614 ± 0.018	1.589IleTyr: 1.589 ± 0.029	0.0IleXaa: 0.0 ± 0.0
Lys	4.315LysAla: 4.315 ± 0.055	0.293LysCys: 0.293 ± 0.013	2.458LysAsp: 2.458 ± 0.037	3.078LysGlu: 3.078 ± 0.046	1.302LysPhe: 1.302 ± 0.02	3.072LysGly: 3.072 ± 0.045	0.966LysHis: 0.966 ± 0.019	2.311LysIle: 2.311 ± 0.033	2.387LysLys: 2.387 ± 0.044	4.65LysLeu: 4.65 ± 0.054	1.041LysMet: 1.041 ± 0.02	1.623LysAsn: 1.623 ± 0.031	2.173LysPro: 2.173 ± 0.055	2.079LysGln: 2.079 ± 0.034	2.687LysArg: 2.687 ± 0.039	2.772LysSer: 2.772 ± 0.041	2.43LysThr: 2.43 ± 0.041	3.334LysVal: 3.334 ± 0.042	0.492LysTrp: 0.492 ± 0.014	1.187LysTyr: 1.187 ± 0.022	0.0LysXaa: 0.0 ± 0.0
Leu	10.657LeuAla: 10.657 ± 0.098	1.187LeuCys: 1.187 ± 0.027	5.783LeuAsp: 5.783 ± 0.056	6.313LeuGlu: 6.313 ± 0.065	4.079LeuPhe: 4.079 ± 0.058	7.124LeuGly: 7.124 ± 0.07	2.159LeuHis: 2.159 ± 0.033	5.498LeuIle: 5.498 ± 0.064	4.871LeuLys: 4.871 ± 0.057	10.849LeuLeu: 10.849 ± 0.11	2.549LeuMet: 2.549 ± 0.039	4.139LeuAsn: 4.139 ± 0.047	4.877LeuPro: 4.877 ± 0.059	4.753LeuGln: 4.753 ± 0.054	6.361LeuArg: 6.361 ± 0.071	7.851LeuSer: 7.851 ± 0.068	6.028LeuThr: 6.028 ± 0.064	6.265LeuVal: 6.265 ± 0.064	1.278LeuTrp: 1.278 ± 0.028	2.794LeuTyr: 2.794 ± 0.039	0.0LeuXaa: 0.0 ± 0.0
Met	2.563MetAla: 2.563 ± 0.038	0.194MetCys: 0.194 ± 0.011	1.3MetAsp: 1.3 ± 0.025	1.484MetGlu: 1.484 ± 0.024	0.744MetPhe: 0.744 ± 0.019	1.647MetGly: 1.647 ± 0.031	0.481MetHis: 0.481 ± 0.016	1.199MetIle: 1.199 ± 0.024	1.265MetLys: 1.265 ± 0.026	2.661MetLeu: 2.661 ± 0.048	0.621MetMet: 0.621 ± 0.018	1.0MetAsn: 1.0 ± 0.021	1.116MetPro: 1.116 ± 0.025	1.153MetGln: 1.153 ± 0.021	1.511MetArg: 1.511 ± 0.028	1.846MetSer: 1.846 ± 0.028	1.507MetThr: 1.507 ± 0.027	1.458MetVal: 1.458 ± 0.027	0.2MetTrp: 0.2 ± 0.01	0.497MetTyr: 0.497 ± 0.019	0.0MetXaa: 0.0 ± 0.0
Asn	3.583AsnAla: 3.583 ± 0.039	0.362AsnCys: 0.362 ± 0.011	1.99AsnAsp: 1.99 ± 0.043	2.054AsnGlu: 2.054 ± 0.036	1.33AsnPhe: 1.33 ± 0.029	2.931AsnGly: 2.931 ± 0.051	0.829AsnHis: 0.829 ± 0.018	2.104AsnIle: 2.104 ± 0.033	1.559AsnLys: 1.559 ± 0.031	3.68AsnLeu: 3.68 ± 0.045	0.806AsnMet: 0.806 ± 0.019	1.386AsnAsn: 1.386 ± 0.032	2.082AsnPro: 2.082 ± 0.033	1.555AsnGln: 1.555 ± 0.029	2.129AsnArg: 2.129 ± 0.045	2.072AsnSer: 2.072 ± 0.036	1.682AsnThr: 1.682 ± 0.03	2.255AsnVal: 2.255 ± 0.036	0.557AsnTrp: 0.557 ± 0.016	1.202AsnTyr: 1.202 ± 0.024	0.0AsnXaa: 0.0 ± 0.0
Pro	4.19ProAla: 4.19 ± 0.056	0.348ProCys: 0.348 ± 0.015	3.041ProAsp: 3.041 ± 0.038	3.685ProGlu: 3.685 ± 0.048	1.779ProPhe: 1.779 ± 0.03	3.404ProGly: 3.404 ± 0.044	0.989ProHis: 0.989 ± 0.023	2.103ProIle: 2.103 ± 0.032	1.777ProLys: 1.777 ± 0.036	4.428ProLeu: 4.428 ± 0.056	1.008ProMet: 1.008 ± 0.023	1.534ProAsn: 1.534 ± 0.031	1.98ProPro: 1.98 ± 0.034	1.923ProGln: 1.923 ± 0.032	1.905ProArg: 1.905 ± 0.031	2.677ProSer: 2.677 ± 0.037	2.146ProThr: 2.146 ± 0.041	3.557ProVal: 3.557 ± 0.047	0.623ProTrp: 0.623 ± 0.02	1.325ProTyr: 1.325 ± 0.028	0.0ProXaa: 0.0 ± 0.0
Gln	4.509GlnAla: 4.509 ± 0.06	0.387GlnCys: 0.387 ± 0.014	2.096GlnAsp: 2.096 ± 0.033	2.696GlnGlu: 2.696 ± 0.035	1.456GlnPhe: 1.456 ± 0.027	3.078GlnGly: 3.078 ± 0.043	0.954GlnHis: 0.954 ± 0.02	2.106GlnIle: 2.106 ± 0.036	1.781GlnLys: 1.781 ± 0.032	4.301GlnLeu: 4.301 ± 0.053	1.015GlnMet: 1.015 ± 0.02	1.314GlnAsn: 1.314 ± 0.026	1.892GlnPro: 1.892 ± 0.035	2.274GlnGln: 2.274 ± 0.044	2.892GlnArg: 2.892 ± 0.04	2.573GlnSer: 2.573 ± 0.034	2.181GlnThr: 2.181 ± 0.041	2.903GlnVal: 2.903 ± 0.037	0.687GlnTrp: 0.687 ± 0.018	1.179GlnTyr: 1.179 ± 0.026	0.0GlnXaa: 0.0 ± 0.0
Arg	4.722ArgAla: 4.722 ± 0.05	0.583ArgCys: 0.583 ± 0.017	3.106ArgAsp: 3.106 ± 0.035	4.03ArgGlu: 4.03 ± 0.053	2.722ArgPhe: 2.722 ± 0.04	3.322ArgGly: 3.322 ± 0.045	1.534ArgHis: 1.534 ± 0.028	3.557ArgIle: 3.557 ± 0.039	2.773ArgLys: 2.773 ± 0.035	7.048ArgLeu: 7.048 ± 0.069	1.517ArgMet: 1.517 ± 0.027	2.24ArgAsn: 2.24 ± 0.035	2.35ArgPro: 2.35 ± 0.038	2.752ArgGln: 2.752 ± 0.042	4.128ArgArg: 4.128 ± 0.042	3.38ArgSer: 3.38 ± 0.038	2.5ArgThr: 2.5 ± 0.037	3.748ArgVal: 3.748 ± 0.044	0.906ArgTrp: 0.906 ± 0.021	2.242ArgTyr: 2.242 ± 0.047	0.0ArgXaa: 0.0 ± 0.0
Ser	6.281SerAla: 6.281 ± 0.061	0.644SerCys: 0.644 ± 0.019	3.703SerAsp: 3.703 ± 0.046	3.934SerGlu: 3.934 ± 0.048	2.594SerPhe: 2.594 ± 0.035	5.633SerGly: 5.633 ± 0.071	1.48SerHis: 1.48 ± 0.025	3.46SerIle: 3.46 ± 0.042	2.578SerLys: 2.578 ± 0.036	7.025SerLeu: 7.025 ± 0.063	1.575SerMet: 1.575 ± 0.026	2.131SerAsn: 2.131 ± 0.037	2.964SerPro: 2.964 ± 0.037	2.654SerGln: 2.654 ± 0.037	3.657SerArg: 3.657 ± 0.044	4.181SerSer: 4.181 ± 0.062	2.879SerThr: 2.879 ± 0.041	4.47SerVal: 4.47 ± 0.056	0.958SerTrp: 0.958 ± 0.026	2.012SerTyr: 2.012 ± 0.035	0.0SerXaa: 0.0 ± 0.0
Thr	4.569ThrAla: 4.569 ± 0.058	0.435ThrCys: 0.435 ± 0.015	2.76ThrAsp: 2.76 ± 0.056	2.885ThrGlu: 2.885 ± 0.05	1.835ThrPhe: 1.835 ± 0.036	3.922ThrGly: 3.922 ± 0.047	1.144ThrHis: 1.144 ± 0.021	2.446ThrIle: 2.446 ± 0.038	1.476ThrLys: 1.476 ± 0.032	6.202ThrLeu: 6.202 ± 0.07	0.965ThrMet: 0.965 ± 0.023	1.413ThrAsn: 1.413 ± 0.029	3.22ThrPro: 3.22 ± 0.04	2.167ThrGln: 2.167 ± 0.042	2.641ThrArg: 2.641 ± 0.043	2.94ThrSer: 2.94 ± 0.045	2.469ThrThr: 2.469 ± 0.041	3.393ThrVal: 3.393 ± 0.044	0.581ThrTrp: 0.581 ± 0.016	1.526ThrTyr: 1.526 ± 0.038	0.0ThrXaa: 0.0 ± 0.0
Val	6.755ValAla: 6.755 ± 0.073	0.817ValCys: 0.817 ± 0.02	4.172ValAsp: 4.172 ± 0.051	4.528ValGlu: 4.528 ± 0.054	2.66ValPhe: 2.66 ± 0.039	4.648ValGly: 4.648 ± 0.056	1.199ValHis: 1.199 ± 0.026	4.121ValIle: 4.121 ± 0.051	3.234ValLys: 3.234 ± 0.039	6.502ValLeu: 6.502 ± 0.065	1.732ValMet: 1.732 ± 0.031	2.751ValAsn: 2.751 ± 0.038	2.214ValPro: 2.214 ± 0.036	2.175ValGln: 2.175 ± 0.036	3.956ValArg: 3.956 ± 0.046	4.94ValSer: 4.94 ± 0.047	3.911ValThr: 3.911 ± 0.074	5.004ValVal: 5.004 ± 0.053	0.909ValTrp: 0.909 ± 0.025	1.991ValTyr: 1.991 ± 0.036	0.0ValXaa: 0.0 ± 0.0
Trp	1.017TrpAla: 1.017 ± 0.025	0.14TrpCys: 0.14 ± 0.008	0.661TrpAsp: 0.661 ± 0.018	0.749TrpGlu: 0.749 ± 0.018	0.563TrpPhe: 0.563 ± 0.018	0.905TrpGly: 0.905 ± 0.023	0.244TrpHis: 0.244 ± 0.012	0.716TrpIle: 0.716 ± 0.021	0.6TrpLys: 0.6 ± 0.018	1.865TrpLeu: 1.865 ± 0.037	0.397TrpMet: 0.397 ± 0.015	0.522TrpAsn: 0.522 ± 0.017	0.56TrpPro: 0.56 ± 0.017	0.416TrpGln: 0.416 ± 0.014	1.423TrpArg: 1.423 ± 0.027	0.97TrpSer: 0.97 ± 0.025	0.675TrpThr: 0.675 ± 0.023	0.9TrpVal: 0.9 ± 0.025	0.221TrpTrp: 0.221 ± 0.011	0.353TrpTyr: 0.353 ± 0.014	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.639TyrAla: 2.639 ± 0.034	0.363TyrCys: 0.363 ± 0.012	1.959TyrAsp: 1.959 ± 0.085	1.811TyrGlu: 1.811 ± 0.033	1.407TyrPhe: 1.407 ± 0.029	2.192TyrGly: 2.192 ± 0.035	0.704TyrHis: 0.704 ± 0.02	1.437TyrIle: 1.437 ± 0.027	1.178TyrLys: 1.178 ± 0.023	3.411TyrLeu: 3.411 ± 0.039	0.63TyrMet: 0.63 ± 0.019	1.071TyrAsn: 1.071 ± 0.028	1.476TyrPro: 1.476 ± 0.033	1.491TyrGln: 1.491 ± 0.029	2.103TyrArg: 2.103 ± 0.034	2.067TyrSer: 2.067 ± 0.038	1.43TyrThr: 1.43 ± 0.033	1.984TyrVal: 1.984 ± 0.041	0.532TyrTrp: 0.532 ± 0.015	1.099TyrTyr: 1.099 ± 0.025	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 6751 proteins (2111145 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---